data_ma-bak-cepc-0634 _entry.id ma-bak-cepc-0634 _entry.ma_collection_id ma-bak-cepc _struct.entry_id ma-bak-cepc-0634 _struct.title 'Predicted interaction between ALB1 and ARX1' _struct.pdbx_model_details ;Predicted interaction between Ribosome biogenesis protein ALB1 and Probable metalloprotease ARX1 (EC 3.-.-.-) (Associated with ribosomal export complex protein 1) Model generated using AlphaFold2 with a 200 residue separation between the chains starting from a paired Multiple Sequence Alignment(pMSA) ; _struct.pdbx_structure_determination_methodology computational loop_ _ma_data.content_type _ma_data.id _ma_data.name "model coordinates" 1 "Model 3" target 2 "ALB1" target 3 "ARX1" "coevolution MSA" 4 "Paired MSA for the dimer" _ma_data_group.ordinal_id 1 _ma_data_group.group_id 1 _ma_data_group.data_id 1 loop_ _software.pdbx_ordinal _software.name _software.description _software.date _software.classification _software.type _software.version _software.citation_id 1 AlphaFold "Structure prediction" ? 'model building' package 2.0.0 1 loop_ _ma_protocol_step.ordinal_id _ma_protocol_step.protocol_id _ma_protocol_step.step_id _ma_protocol_step.method_type _ma_protocol_step.details 1 1 1 "coevolution MSA" "Create paired MSAs for the dimers" 2 1 2 "modeling" "Model using AlphaFold with a 200 residue gap between the two chains" loop_ _audit_author.name _audit_author.pdbx_ordinal "Humphreys, Ian R." 1 "Pei, Jimin" 2 "Baek, Minkyung" 3 "Krishnakumar, Aditya" 4 "Anishchenko, Ivan" 5 "Ovchinnikov, Sergey" 6 "Zhang, Jing" 7 "Ness, Travis J." 8 "Banjade, Sudeep" 9 "Bagde, Saket R." 10 "Stancheva, Viktoriya G." 11 "Li, Xiao-Han" 12 "Liu, Kaixian" 13 "Zheng, Zhi" 14 "Barrero, Daniel J." 15 "Roy, Upasana" 16 "Kuper, Jochen" 17 "Fernandez, Israel S." 18 "Szakal, Barnabas" 19 "Branzei, Dana" 20 "Rizo, Josep" 21 "Kisker, Caroline" 22 "Greene, Eric C." 23 "Biggins, Sue" 24 "Keeney, Scott" 25 "Miller, Elizabeth A." 26 "Fromme, J. Christopher" 27 "Hendrickson, Tamara L." 28 "Cong, Qian" 29 "Baker, David" 30 loop_ _citation.id _citation.title _citation.book_publisher _citation.journal_full _citation.journal_id_ASTM _citation.journal_id_CSD _citation.journal_id_ISSN _citation.journal_volume _citation.page_first _citation.page_last _citation.pdbx_database_id_DOI _citation.pdbx_database_id_PubMed _citation.country _citation.year primary 'Computed structures of core eukaryotic protein complexes' ? Science ? ? 0036-8075 374 ? ? 10.1126/science.abm4805 34762488 US 2021 1 'Highly accurate protein structure prediction with AlphaFold.' ? Nature ? ? 0028-0836 596 583 589 10.1038/s41586-021-03819-2 34265844 ? 2021 loop_ _citation_author.citation_id _citation_author.name _citation_author.ordinal primary "Humphreys, Ian R." 1 primary "Pei, Jimin" 2 primary "Baek, Minkyung" 3 primary "Krishnakumar, Aditya" 4 primary "Anishchenko, Ivan" 5 primary "Ovchinnikov, Sergey" 6 primary "Zhang, Jing" 7 primary "Ness, Travis J." 8 primary "Banjade, Sudeep" 9 primary "Bagde, Saket R." 10 primary "Stancheva, Viktoriya G." 11 primary "Li, Xiao-Han" 12 primary "Liu, Kaixian" 13 primary "Zheng, Zhi" 14 primary "Barrero, Daniel J." 15 primary "Roy, Upasana" 16 primary "Kuper, Jochen" 17 primary "Fernandez, Israel S." 18 primary "Szakal, Barnabas" 19 primary "Branzei, Dana" 20 primary "Rizo, Josep" 21 primary "Kisker, Caroline" 22 primary "Greene, Eric C." 23 primary "Biggins, Sue" 24 primary "Keeney, Scott" 25 primary "Miller, Elizabeth A." 26 primary "Fromme, J. Christopher" 27 primary "Hendrickson, Tamara L." 28 primary "Cong, Qian" 29 primary "Baker, David" 30 1 'Jumper, J.' 31 1 'Evans, R.' 32 1 'Pritzel, A.' 33 1 'Green, T.' 34 1 'Figurnov, M.' 35 1 'Ronneberger, O.' 36 1 'Tunyasuvunakool, K.' 37 1 'Bates, R.' 38 1 'Zidek, A.' 39 1 'Potapenko, A.' 40 1 'Bridgland, A.' 41 1 'Meyer, C.' 42 1 'Kohl, S.A.A.' 43 1 'Ballard, A.J.' 44 1 'Cowie, A.' 45 1 'Romera-Paredes, B.' 46 1 'Nikolov, S.' 47 1 'Jain, R.' 48 1 'Adler, J.' 49 1 'Back, T.' 50 1 'Petersen, S.' 51 1 'Reiman, D.' 52 1 'Clancy, E.' 53 1 'Zielinski, M.' 54 1 'Steinegger, M.' 55 1 'Pacholska, M.' 56 1 'Berghammer, T.' 57 1 'Bodenstein, S.' 58 1 'Silver, D.' 59 1 'Vinyals, O.' 60 1 'Senior, A.W.' 61 1 'Kavukcuoglu, K.' 62 1 'Kohli, P.' 63 1 'Hassabis, D.' 64 _ma_software_group.group_id 1 _ma_software_group.ordinal_id 1 _ma_software_group.software_id 1 loop_ _ma_target_entity.data_id _ma_target_entity.entity_id _ma_target_entity.origin 2 1 "reference database" 3 2 "reference database" loop_ _ma_target_entity_instance.asym_id _ma_target_entity_instance.details _ma_target_entity_instance.entity_id A . 1 B . 2 loop_ _ma_target_ref_db_details.db_accession _ma_target_ref_db_details.db_code _ma_target_ref_db_details.db_name _ma_target_ref_db_details.ncbi_taxonomy_id _ma_target_ref_db_details.organism_scientific _ma_target_ref_db_details.seq_db_align_begin _ma_target_ref_db_details.seq_db_align_end _ma_target_ref_db_details.seq_db_isoform _ma_target_ref_db_details.target_entity_id 1294385_1:000ad5 . OrthoDB 1294385 "Saccharomyces cerevisiae YJM1573" 1 175 ? 1 1294385_1:00048b . OrthoDB 1294385 "Saccharomyces cerevisiae YJM1573" 1 593 ? 2 P47019 . UNP 559292 "Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)" 1 175 ? 1 Q03862 . UNP 559292 "Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)" 1 593 ? 2 loop_ _ma_entry_associated_files.id _ma_entry_associated_files.entry_id _ma_entry_associated_files.file_url _ma_entry_associated_files.file_type _ma_entry_associated_files.file_format _ma_entry_associated_files.file_content _ma_entry_associated_files.details 1 ma-bak-cepc-0634 https://modelarchive.org/api/projects/ma-bak-cepc-0634?type=materials_procedures__accompanying_data_file_name archive zip 'archive with multiple files' . loop_ _ma_associated_archive_file_details.id _ma_associated_archive_file_details.archive_file_id _ma_associated_archive_file_details.file_path _ma_associated_archive_file_details.file_format _ma_associated_archive_file_details.file_content _ma_associated_archive_file_details.description _ma_associated_archive_file_details.data_id 1 1 ma-bak-cepc-0634_predicted_aligned_error_v1.cif cif "local pairwise QA scores" ? . 2 1 P47019_Q03862.a3m a3m "multiple sequence alignments" ? 4 loop_ _ma_qa_metric.id _ma_qa_metric.mode _ma_qa_metric.name _ma_qa_metric.software_group_id _ma_qa_metric.type 1 global pLDDT 1 pLDDT 2 local pLDDT 1 pLDDT 3 local-pairwise PAE 1 PAE 4 local-pairwise "contact probability" 1 "contact probability" _ma_qa_metric_global.metric_id 1 _ma_qa_metric_global.metric_value 78.32 _ma_qa_metric_global.model_id 1 _ma_qa_metric_global.ordinal_id 1 loop_ _ma_qa_metric_local.label_asym_id _ma_qa_metric_local.label_comp_id _ma_qa_metric_local.label_seq_id _ma_qa_metric_local.metric_id _ma_qa_metric_local.metric_value _ma_qa_metric_local.model_id _ma_qa_metric_local.ordinal_id A MET 1 2 40.9 1 1 A PRO 2 2 44.0 1 2 A SER 3 2 45.6 1 3 A LYS 4 2 49.1 1 4 A ASN 5 2 52.1 1 5 A SER 6 2 49.4 1 6 A ILE 7 2 55.6 1 7 A ASN 8 2 46.9 1 8 A ARG 9 2 53.0 1 9 A PRO 10 2 56.9 1 10 A LYS 11 2 60.7 1 11 A LEU 12 2 61.7 1 12 A THR 13 2 71.0 1 13 A SER 14 2 73.2 1 14 A ASN 15 2 78.9 1 15 A LEU 16 2 78.7 1 16 A HIS 17 2 79.5 1 17 A HIS 18 2 81.9 1 18 A LYS 19 2 85.8 1 19 A VAL 20 2 85.4 1 20 A HIS 21 2 84.6 1 21 A SER 22 2 85.2 1 22 A LEU 23 2 84.4 1 23 A ASN 24 2 83.4 1 24 A LYS 25 2 84.9 1 25 A LYS 26 2 79.5 1 26 A ARG 27 2 77.9 1 27 A ALA 28 2 76.1 1 28 A GLN 29 2 72.5 1 29 A ARG 30 2 68.6 1 30 A GLU 31 2 71.1 1 31 A ARG 32 2 63.7 1 32 A ALA 33 2 62.4 1 33 A GLY 34 2 47.4 1 34 A LEU 35 2 49.6 1 35 A LEU 36 2 44.8 1 36 A LYS 37 2 51.3 1 37 A PRO 38 2 54.5 1 38 A ALA 39 2 55.8 1 39 A ARG 40 2 50.2 1 40 A SER 41 2 54.5 1 41 A SER 42 2 55.6 1 42 A VAL 43 2 56.0 1 43 A ASN 44 2 54.9 1 44 A SER 45 2 52.6 1 45 A LYS 46 2 54.9 1 46 A SER 47 2 51.4 1 47 A GLY 48 2 50.3 1 48 A GLU 49 2 49.1 1 49 A ILE 50 2 47.3 1 50 A LYS 51 2 45.1 1 51 A SER 52 2 47.7 1 52 A VAL 53 2 50.9 1 53 A ALA 54 2 51.4 1 54 A LEU 55 2 50.5 1 55 A ASP 56 2 50.4 1 56 A LEU 57 2 52.3 1 57 A TYR 58 2 47.1 1 58 A PHE 59 2 54.5 1 59 A GLN 60 2 44.7 1 60 A ASN 61 2 42.6 1 61 A LYS 62 2 39.3 1 62 A LYS 63 2 38.1 1 63 A ASN 64 2 36.3 1 64 A GLU 65 2 32.7 1 65 A SER 66 2 33.7 1 66 A GLN 67 2 31.8 1 67 A ASN 68 2 30.0 1 68 A SER 69 2 37.5 1 69 A THR 70 2 31.1 1 70 A ALA 71 2 29.3 1 71 A VAL 72 2 33.3 1 72 A THR 73 2 28.4 1 73 A LEU 74 2 31.8 1 74 A GLN 75 2 25.9 1 75 A ASN 76 2 27.2 1 76 A ALA 77 2 28.8 1 77 A SER 78 2 28.5 1 78 A SER 79 2 33.9 1 79 A SER 80 2 33.3 1 80 A PRO 81 2 39.3 1 81 A ALA 82 2 39.7 1 82 A SER 83 2 38.0 1 83 A ILE 84 2 42.9 1 84 A THR 85 2 44.3 1 85 A THR 86 2 39.7 1 86 A ARG 87 2 50.3 1 87 A THR 88 2 54.3 1 88 A LEU 89 2 57.3 1 89 A SER 90 2 78.3 1 90 A LYS 91 2 78.1 1 91 A LYS 92 2 77.5 1 92 A ARG 93 2 74.6 1 93 A ALA 94 2 78.4 1 94 A LYS 95 2 85.2 1 95 A LYS 96 2 86.4 1 96 A ILE 97 2 79.6 1 97 A GLU 98 2 83.8 1 98 A ARG 99 2 88.0 1 99 A ASN 100 2 84.6 1 100 A LEU 101 2 81.1 1 101 A LYS 102 2 84.7 1 102 A TYR 103 2 84.4 1 103 A ALA 104 2 80.2 1 104 A THR 105 2 79.0 1 105 A GLN 106 2 77.5 1 106 A ARG 107 2 77.9 1 107 A LYS 108 2 77.7 1 108 A LEU 109 2 75.5 1 109 A LEU 110 2 72.0 1 110 A VAL 111 2 75.6 1 111 A ASP 112 2 72.1 1 112 A ALA 113 2 66.4 1 113 A SER 114 2 62.4 1 114 A ALA 115 2 66.6 1 115 A LYS 116 2 58.3 1 116 A LEU 117 2 54.9 1 117 A GLU 118 2 53.6 1 118 A ASP 119 2 51.8 1 119 A GLU 120 2 45.8 1 120 A MET 121 2 38.9 1 121 A ASP 122 2 34.2 1 122 A ILE 123 2 33.9 1 123 A ASP 124 2 31.6 1 124 A LEU 125 2 29.8 1 125 A ASP 126 2 28.8 1 126 A GLY 127 2 28.6 1 127 A GLY 128 2 30.3 1 128 A LYS 129 2 32.6 1 129 A LYS 130 2 34.9 1 130 A VAL 131 2 41.7 1 131 A LYS 132 2 40.2 1 132 A GLU 133 2 41.5 1 133 A ASN 134 2 43.3 1 134 A GLU 135 2 51.1 1 135 A LYS 136 2 56.6 1 136 A LYS 137 2 63.2 1 137 A SER 138 2 73.7 1 138 A SER 139 2 75.4 1 139 A LEU 140 2 78.2 1 140 A THR 141 2 81.0 1 141 A LEU 142 2 82.0 1 142 A VAL 143 2 82.3 1 143 A LYS 144 2 83.0 1 144 A GLU 145 2 83.7 1 145 A ALA 146 2 82.2 1 146 A LEU 147 2 83.5 1 147 A TRP 148 2 86.0 1 148 A SER 149 2 83.8 1 149 A VAL 150 2 80.9 1 150 A ILE 151 2 81.7 1 151 A ASP 152 2 82.0 1 152 A ASP 153 2 75.0 1 153 A THR 154 2 69.6 1 154 A ALA 155 2 66.7 1 155 A SER 156 2 63.0 1 156 A GLN 157 2 54.4 1 157 A GLY 158 2 54.1 1 158 A LEU 159 2 54.8 1 159 A ILE 160 2 55.8 1 160 A ILE 161 2 58.0 1 161 A GLU 162 2 57.4 1 162 A ASN 163 2 52.7 1 163 A GLY 164 2 62.5 1 164 A GLN 165 2 78.8 1 165 A GLY 166 2 87.0 1 166 A THR 167 2 90.8 1 167 A THR 168 2 92.6 1 168 A LEU 169 2 91.6 1 169 A GLY 170 2 88.6 1 170 A GLY 171 2 86.7 1 171 A PRO 172 2 85.4 1 172 A PHE 173 2 83.6 1 173 A PHE 174 2 83.0 1 174 A PRO 175 2 70.8 1 175 B MET 1 2 42.8 1 176 B ALA 2 2 34.4 1 177 B LEU 3 2 39.8 1 178 B ALA 4 2 44.0 1 179 B ILE 5 2 50.8 1 180 B SER 6 2 60.2 1 181 B HIS 7 2 66.0 1 182 B GLU 8 2 68.8 1 183 B ASP 9 2 65.4 1 184 B THR 10 2 65.0 1 185 B GLN 11 2 67.8 1 186 B ILE 12 2 70.5 1 187 B LEU 13 2 66.3 1 188 B LEU 14 2 66.4 1 189 B LYS 15 2 71.4 1 190 B ASP 16 2 71.2 1 191 B LYS 17 2 74.9 1 192 B ASN 18 2 76.6 1 193 B ILE 19 2 82.0 1 194 B LEU 20 2 85.1 1 195 B GLN 21 2 86.7 1 196 B GLU 22 2 86.4 1 197 B SER 23 2 86.7 1 198 B VAL 24 2 88.9 1 199 B LEU 25 2 90.6 1 200 B ASN 26 2 90.5 1 201 B LYS 27 2 91.0 1 202 B TYR 28 2 92.3 1 203 B ARG 29 2 92.3 1 204 B THR 30 2 91.7 1 205 B ALA 31 2 92.9 1 206 B GLY 32 2 93.8 1 207 B GLN 33 2 93.6 1 208 B ILE 34 2 93.9 1 209 B ALA 35 2 95.0 1 210 B GLN 36 2 94.4 1 211 B THR 37 2 94.5 1 212 B ALA 38 2 95.1 1 213 B LEU 39 2 95.6 1 214 B LYS 40 2 94.7 1 215 B TYR 41 2 94.9 1 216 B VAL 42 2 95.1 1 217 B THR 43 2 94.7 1 218 B SER 44 2 93.7 1 219 B LEU 45 2 93.2 1 220 B ILE 46 2 94.2 1 221 B ASN 47 2 92.5 1 222 B ASP 48 2 91.5 1 223 B SER 49 2 91.3 1 224 B TYR 50 2 91.1 1 225 B HIS 51 2 89.2 1 226 B SER 52 2 87.8 1 227 B LYS 53 2 82.1 1 228 B THR 54 2 80.6 1 229 B THR 55 2 76.8 1 230 B GLN 56 2 74.7 1 231 B ARG 57 2 84.0 1 232 B GLN 58 2 85.5 1 233 B LEU 59 2 91.2 1 234 B THR 60 2 92.4 1 235 B VAL 61 2 94.2 1 236 B PRO 62 2 93.3 1 237 B GLU 63 2 92.6 1 238 B LEU 64 2 93.8 1 239 B CYS 65 2 94.6 1 240 B LEU 66 2 93.9 1 241 B LEU 67 2 93.1 1 242 B THR 68 2 94.5 1 243 B ASP 69 2 95.1 1 244 B SER 70 2 94.1 1 245 B PHE 71 2 93.8 1 246 B ILE 72 2 94.2 1 247 B LEU 73 2 92.5 1 248 B THR 74 2 90.7 1 249 B ARG 75 2 89.4 1 250 B LEU 76 2 89.7 1 251 B GLU 77 2 85.9 1 252 B GLN 78 2 82.9 1 253 B TYR 79 2 75.7 1 254 B TYR 80 2 71.5 1 255 B LYS 81 2 67.3 1 256 B ASN 82 2 66.1 1 257 B LYS 83 2 71.9 1 258 B VAL 84 2 74.2 1 259 B ASN 85 2 76.7 1 260 B GLU 86 2 83.3 1 261 B ARG 87 2 87.1 1 262 B GLY 88 2 90.3 1 263 B ILE 89 2 92.7 1 264 B ALA 90 2 91.7 1 265 B ILE 91 2 92.3 1 266 B PRO 92 2 93.7 1 267 B THR 93 2 95.5 1 268 B THR 94 2 95.1 1 269 B ILE 95 2 96.4 1 270 B ASP 96 2 96.0 1 271 B ILE 97 2 95.9 1 272 B ASP 98 2 95.0 1 273 B GLN 99 2 94.6 1 274 B ILE 100 2 95.4 1 275 B SER 101 2 93.6 1 276 B GLY 102 2 91.3 1 277 B GLY 103 2 86.4 1 278 B TRP 104 2 92.0 1 279 B CYS 105 2 87.8 1 280 B PRO 106 2 88.5 1 281 B GLU 107 2 91.1 1 282 B ILE 108 2 89.9 1 283 B ASP 109 2 87.9 1 284 B ASP 110 2 85.9 1 285 B THR 111 2 85.3 1 286 B GLN 112 2 87.1 1 287 B ASN 113 2 87.8 1 288 B LEU 114 2 89.4 1 289 B LEU 115 2 88.9 1 290 B ASN 116 2 88.4 1 291 B TRP 117 2 87.7 1 292 B ASN 118 2 86.5 1 293 B LYS 119 2 79.8 1 294 B GLY 120 2 71.7 1 295 B LYS 121 2 62.2 1 296 B ASP 122 2 66.9 1 297 B SER 123 2 73.1 1 298 B THR 124 2 83.0 1 299 B PHE 125 2 89.0 1 300 B ALA 126 2 89.3 1 301 B SER 127 2 92.2 1 302 B SER 128 2 91.7 1 303 B VAL 129 2 91.1 1 304 B THR 130 2 90.6 1 305 B GLY 131 2 90.3 1 306 B THR 132 2 92.7 1 307 B LEU 133 2 94.0 1 308 B ARG 134 2 93.2 1 309 B PRO 135 2 91.7 1 310 B GLY 136 2 92.3 1 311 B ASP 137 2 95.2 1 312 B LEU 138 2 96.1 1 313 B VAL 139 2 96.4 1 314 B LYS 140 2 97.0 1 315 B ILE 141 2 96.8 1 316 B THR 142 2 96.0 1 317 B LEU 143 2 95.1 1 318 B GLY 144 2 93.9 1 319 B VAL 145 2 93.8 1 320 B HIS 146 2 91.7 1 321 B ILE 147 2 90.7 1 322 B ASP 148 2 87.0 1 323 B GLY 149 2 86.0 1 324 B TYR 150 2 89.3 1 325 B THR 151 2 89.9 1 326 B SER 152 2 92.6 1 327 B GLU 153 2 93.3 1 328 B VAL 154 2 95.0 1 329 B SER 155 2 95.5 1 330 B HIS 156 2 96.3 1 331 B THR 157 2 96.3 1 332 B MET 158 2 94.8 1 333 B VAL 159 2 95.1 1 334 B ILE 160 2 94.7 1 335 B TYR 161 2 92.9 1 336 B PRO 162 2 89.1 1 337 B VAL 163 2 83.2 1 338 B ASP 164 2 80.3 1 339 B GLU 165 2 76.9 1 340 B THR 166 2 78.4 1 341 B LYS 167 2 75.1 1 342 B PRO 168 2 76.1 1 343 B ILE 169 2 80.5 1 344 B PRO 170 2 80.8 1 345 B GLN 171 2 83.8 1 346 B PRO 172 2 84.4 1 347 B THR 173 2 84.0 1 348 B GLY 174 2 76.0 1 349 B PRO 175 2 90.5 1 350 B LEU 176 2 93.3 1 351 B LEU 177 2 93.1 1 352 B GLY 178 2 91.6 1 353 B GLY 179 2 92.4 1 354 B LYS 180 2 95.6 1 355 B ALA 181 2 95.6 1 356 B ASP 182 2 95.3 1 357 B ALA 183 2 96.5 1 358 B VAL 184 2 96.7 1 359 B ALA 185 2 95.9 1 360 B ALA 186 2 96.6 1 361 B ALA 187 2 96.8 1 362 B HIS 188 2 95.7 1 363 B ILE 189 2 96.1 1 364 B ALA 190 2 97.1 1 365 B MET 191 2 96.4 1 366 B GLU 192 2 95.6 1 367 B THR 193 2 96.4 1 368 B VAL 194 2 97.0 1 369 B VAL 195 2 96.3 1 370 B ALA 196 2 95.6 1 371 B LEU 197 2 95.3 1 372 B LEU 198 2 95.1 1 373 B ALA 199 2 94.0 1 374 B CYS 200 2 93.3 1 375 B ALA 201 2 92.5 1 376 B LEU 202 2 92.2 1 377 B THR 203 2 89.8 1 378 B PRO 204 2 87.8 1 379 B GLU 205 2 89.1 1 380 B LYS 206 2 89.7 1 381 B LEU 207 2 90.7 1 382 B PRO 208 2 90.2 1 383 B ALA 209 2 88.7 1 384 B SER 210 2 87.3 1 385 B LEU 211 2 85.8 1 386 B GLY 212 2 69.2 1 387 B GLY 213 2 67.3 1 388 B THR 214 2 59.7 1 389 B SER 215 2 63.2 1 390 B SER 216 2 70.4 1 391 B GLY 217 2 82.3 1 392 B ILE 218 2 91.3 1 393 B THR 219 2 92.0 1 394 B GLY 220 2 92.1 1 395 B GLN 221 2 91.9 1 396 B LEU 222 2 93.5 1 397 B ILE 223 2 95.6 1 398 B ARG 224 2 95.0 1 399 B THR 225 2 94.1 1 400 B ILE 226 2 95.5 1 401 B VAL 227 2 97.0 1 402 B ASP 228 2 95.3 1 403 B THR 229 2 94.7 1 404 B ILE 230 2 96.2 1 405 B ALA 231 2 95.6 1 406 B ARG 232 2 93.0 1 407 B SER 233 2 92.8 1 408 B TYR 234 2 93.4 1 409 B ASN 235 2 92.8 1 410 B CYS 236 2 95.1 1 411 B GLY 237 2 94.7 1 412 B VAL 238 2 97.0 1 413 B VAL 239 2 96.7 1 414 B PRO 240 2 94.1 1 415 B GLY 241 2 89.7 1 416 B SER 242 2 95.5 1 417 B ARG 243 2 94.0 1 418 B VAL 244 2 94.9 1 419 B ARG 245 2 90.4 1 420 B ARG 246 2 90.1 1 421 B ILE 247 2 85.5 1 422 B ARG 248 2 78.8 1 423 B ARG 249 2 71.2 1 424 B PHE 250 2 60.6 1 425 B LEU 251 2 57.7 1 426 B ALA 252 2 50.3 1 427 B GLY 253 2 50.0 1 428 B GLN 254 2 57.7 1 429 B ASN 255 2 50.0 1 430 B GLU 256 2 54.4 1 431 B GLY 257 2 49.0 1 432 B ILE 258 2 55.7 1 433 B VAL 259 2 59.6 1 434 B ALA 260 2 60.6 1 435 B GLU 261 2 68.5 1 436 B ARG 262 2 70.6 1 437 B GLU 263 2 75.3 1 438 B TYR 264 2 82.5 1 439 B LYS 265 2 87.8 1 440 B GLY 266 2 89.6 1 441 B VAL 267 2 93.2 1 442 B VAL 268 2 92.3 1 443 B TRP 269 2 94.6 1 444 B THR 270 2 92.0 1 445 B GLU 271 2 92.6 1 446 B SER 272 2 90.4 1 447 B HIS 273 2 91.5 1 448 B GLN 274 2 92.3 1 449 B GLU 275 2 90.8 1 450 B ALA 276 2 89.2 1 451 B ASP 277 2 89.3 1 452 B LEU 278 2 86.5 1 453 B LEU 279 2 85.7 1 454 B SER 280 2 84.1 1 455 B ASN 281 2 79.8 1 456 B THR 282 2 74.1 1 457 B ASP 283 2 65.0 1 458 B ALA 284 2 57.4 1 459 B LYS 285 2 54.6 1 460 B ASP 286 2 49.5 1 461 B LEU 287 2 49.9 1 462 B THR 288 2 47.1 1 463 B VAL 289 2 41.8 1 464 B VAL 290 2 39.8 1 465 B ASP 291 2 41.3 1 466 B ARG 292 2 41.3 1 467 B GLY 293 2 37.7 1 468 B GLN 294 2 34.3 1 469 B SER 295 2 39.6 1 470 B THR 296 2 35.3 1 471 B PRO 297 2 41.3 1 472 B PHE 298 2 38.8 1 473 B THR 299 2 43.1 1 474 B ASN 300 2 45.7 1 475 B VAL 301 2 55.8 1 476 B SER 302 2 67.7 1 477 B ALA 303 2 73.3 1 478 B ILE 304 2 80.0 1 479 B PRO 305 2 81.1 1 480 B SER 306 2 83.8 1 481 B ASP 307 2 87.4 1 482 B ASP 308 2 86.5 1 483 B PHE 309 2 89.2 1 484 B VAL 310 2 90.5 1 485 B VAL 311 2 92.2 1 486 B GLN 312 2 90.7 1 487 B SER 313 2 89.3 1 488 B GLY 314 2 89.1 1 489 B GLU 315 2 91.0 1 490 B VAL 316 2 92.7 1 491 B TYR 317 2 94.6 1 492 B LEU 318 2 94.7 1 493 B ILE 319 2 96.7 1 494 B ASP 320 2 96.1 1 495 B LEU 321 2 97.9 1 496 B LYS 322 2 97.7 1 497 B MET 323 2 97.7 1 498 B ALA 324 2 97.0 1 499 B SER 325 2 94.2 1 500 B LEU 326 2 93.0 1 501 B GLU 327 2 90.7 1 502 B HIS 328 2 87.7 1 503 B CYS 329 2 88.1 1 504 B THR 330 2 82.9 1 505 B LYS 331 2 84.5 1 506 B LYS 332 2 86.8 1 507 B GLY 333 2 90.7 1 508 B LEU 334 2 94.0 1 509 B VAL 335 2 95.3 1 510 B THR 336 2 94.2 1 511 B LEU 337 2 93.0 1 512 B GLU 338 2 91.7 1 513 B THR 339 2 90.5 1 514 B VAL 340 2 89.7 1 515 B ASP 341 2 85.2 1 516 B SER 342 2 82.6 1 517 B TYR 343 2 79.2 1 518 B THR 344 2 67.4 1 519 B GLY 345 2 61.4 1 520 B LYS 346 2 61.7 1 521 B SER 347 2 57.8 1 522 B HIS 348 2 59.3 1 523 B LYS 349 2 66.7 1 524 B ALA 350 2 65.7 1 525 B GLY 351 2 70.2 1 526 B GLU 352 2 80.7 1 527 B LEU 353 2 87.4 1 528 B ILE 354 2 89.2 1 529 B ALA 355 2 90.3 1 530 B ARG 356 2 89.1 1 531 B PRO 357 2 89.7 1 532 B GLY 358 2 88.8 1 533 B ALA 359 2 90.6 1 534 B TYR 360 2 90.5 1 535 B VAL 361 2 87.6 1 536 B ARG 362 2 87.0 1 537 B ASP 363 2 81.3 1 538 B PHE 364 2 76.8 1 539 B ALA 365 2 72.0 1 540 B GLN 366 2 74.6 1 541 B THR 367 2 77.5 1 542 B HIS 368 2 83.0 1 543 B ILE 369 2 85.3 1 544 B LEU 370 2 89.4 1 545 B LYS 371 2 91.4 1 546 B LEU 372 2 91.4 1 547 B LYS 373 2 92.1 1 548 B THR 374 2 91.9 1 549 B SER 375 2 93.6 1 550 B ARG 376 2 92.9 1 551 B GLN 377 2 92.6 1 552 B LEU 378 2 93.6 1 553 B LEU 379 2 92.1 1 554 B THR 380 2 91.7 1 555 B LYS 381 2 92.5 1 556 B ILE 382 2 91.6 1 557 B ASP 383 2 87.8 1 558 B LYS 384 2 86.5 1 559 B GLN 385 2 81.0 1 560 B GLY 386 2 76.3 1 561 B VAL 387 2 81.2 1 562 B TYR 388 2 87.5 1 563 B PRO 389 2 89.7 1 564 B PHE 390 2 91.9 1 565 B LYS 391 2 94.2 1 566 B LEU 392 2 93.7 1 567 B SER 393 2 93.4 1 568 B HIS 394 2 93.2 1 569 B LEU 395 2 92.4 1 570 B SER 396 2 92.3 1 571 B SER 397 2 89.4 1 572 B ASN 398 2 88.3 1 573 B PHE 399 2 88.5 1 574 B PRO 400 2 86.1 1 575 B PHE 401 2 79.1 1 576 B VAL 402 2 69.8 1 577 B HIS 403 2 68.8 1 578 B GLU 404 2 70.5 1 579 B ASN 405 2 78.6 1 580 B GLU 406 2 83.0 1 581 B GLU 407 2 86.7 1 582 B GLU 408 2 86.9 1 583 B LEU 409 2 86.9 1 584 B GLN 410 2 89.6 1 585 B SER 411 2 91.1 1 586 B LEU 412 2 92.0 1 587 B LYS 413 2 92.1 1 588 B LYS 414 2 92.1 1 589 B ASP 415 2 92.6 1 590 B LEU 416 2 93.1 1 591 B LYS 417 2 91.8 1 592 B SER 418 2 91.8 1 593 B PHE 419 2 94.0 1 594 B ARG 420 2 91.2 1 595 B LEU 421 2 91.4 1 596 B GLY 422 2 92.5 1 597 B MET 423 2 93.5 1 598 B SER 424 2 91.5 1 599 B GLU 425 2 92.9 1 600 B ILE 426 2 92.3 1 601 B SER 427 2 91.1 1 602 B ASN 428 2 89.6 1 603 B ASN 429 2 89.9 1 604 B TYR 430 2 87.2 1 605 B LEU 431 2 89.5 1 606 B CYS 432 2 88.8 1 607 B VAL 433 2 87.1 1 608 B GLU 434 2 88.1 1 609 B SER 435 2 88.7 1 610 B PRO 436 2 89.2 1 611 B ILE 437 2 92.3 1 612 B GLN 438 2 93.0 1 613 B ILE 439 2 94.2 1 614 B ALA 440 2 95.0 1 615 B ARG 441 2 94.0 1 616 B TRP 442 2 94.6 1 617 B VAL 443 2 93.7 1 618 B PRO 444 2 92.1 1 619 B TRP 445 2 91.3 1 620 B ASP 446 2 90.0 1 621 B HIS 447 2 88.6 1 622 B ILE 448 2 90.0 1 623 B LEU 449 2 87.8 1 624 B LYS 450 2 87.9 1 625 B ALA 451 2 83.2 1 626 B THR 452 2 70.5 1 627 B ASN 453 2 73.4 1 628 B PRO 454 2 68.6 1 629 B ASN 455 2 71.5 1 630 B GLY 456 2 67.6 1 631 B ASN 457 2 68.1 1 632 B LEU 458 2 68.9 1 633 B SER 459 2 62.9 1 634 B TYR 460 2 67.2 1 635 B ASP 461 2 64.1 1 636 B ALA 462 2 60.1 1 637 B THR 463 2 59.7 1 638 B SER 464 2 63.2 1 639 B THR 465 2 55.1 1 640 B LEU 466 2 62.8 1 641 B THR 467 2 70.0 1 642 B LEU 468 2 75.4 1 643 B PRO 469 2 75.6 1 644 B GLY 470 2 77.3 1 645 B HIS 471 2 81.2 1 646 B GLU 472 2 80.5 1 647 B LEU 473 2 84.9 1 648 B PRO 474 2 87.0 1 649 B LEU 475 2 88.2 1 650 B PRO 476 2 83.8 1 651 B LYS 477 2 84.1 1 652 B LEU 478 2 84.8 1 653 B GLY 479 2 80.9 1 654 B VAL 480 2 86.6 1 655 B SER 481 2 86.1 1 656 B ALA 482 2 85.8 1 657 B ILE 483 2 85.8 1 658 B LYS 484 2 87.6 1 659 B LEU 485 2 88.5 1 660 B LYS 486 2 88.5 1 661 B SER 487 2 88.2 1 662 B LEU 488 2 88.8 1 663 B MET 489 2 89.3 1 664 B ASN 490 2 84.8 1 665 B SER 491 2 84.3 1 666 B THR 492 2 82.2 1 667 B LYS 493 2 83.3 1 668 B GLU 494 2 86.2 1 669 B SER 495 2 89.0 1 670 B ILE 496 2 91.4 1 671 B SER 497 2 92.3 1 672 B LEU 498 2 94.6 1 673 B PRO 499 2 94.9 1 674 B VAL 500 2 96.7 1 675 B ALA 501 2 97.4 1 676 B ARG 502 2 96.8 1 677 B GLU 503 2 97.0 1 678 B CYS 504 2 95.8 1 679 B ASN 505 2 95.2 1 680 B THR 506 2 95.2 1 681 B ILE 507 2 95.5 1 682 B VAL 508 2 95.0 1 683 B LEU 509 2 94.5 1 684 B CYS 510 2 93.1 1 685 B ASP 511 2 90.4 1 686 B SER 512 2 87.8 1 687 B SER 513 2 85.4 1 688 B VAL 514 2 84.1 1 689 B SER 515 2 80.7 1 690 B THR 516 2 77.1 1 691 B THR 517 2 80.0 1 692 B ASP 518 2 81.8 1 693 B ARG 519 2 87.3 1 694 B PRO 520 2 90.1 1 695 B GLU 521 2 93.1 1 696 B LEU 522 2 94.7 1 697 B LEU 523 2 94.5 1 698 B ARG 524 2 94.6 1 699 B LEU 525 2 94.0 1 700 B THR 526 2 93.3 1 701 B GLY 527 2 87.7 1 702 B GLY 528 2 84.4 1 703 B SER 529 2 85.8 1 704 B LYS 530 2 86.2 1 705 B THR 531 2 86.2 1 706 B CYS 532 2 90.5 1 707 B GLN 533 2 90.6 1 708 B PRO 534 2 88.8 1 709 B SER 535 2 91.8 1 710 B TRP 536 2 94.0 1 711 B ILE 537 2 94.7 1 712 B HIS 538 2 94.4 1 713 B SER 539 2 93.6 1 714 B GLN 540 2 91.8 1 715 B HIS 541 2 91.6 1 716 B GLU 542 2 90.9 1 717 B LEU 543 2 89.7 1 718 B ASN 544 2 88.3 1 719 B PRO 545 2 86.9 1 720 B GLN 546 2 87.7 1 721 B ASP 547 2 89.2 1 722 B SER 548 2 91.1 1 723 B ILE 549 2 93.1 1 724 B VAL 550 2 92.3 1 725 B GLN 551 2 92.9 1 726 B GLY 552 2 93.3 1 727 B ILE 553 2 94.1 1 728 B PHE 554 2 94.4 1 729 B GLN 555 2 93.7 1 730 B LEU 556 2 93.9 1 731 B ALA 557 2 92.9 1 732 B THR 558 2 93.8 1 733 B LEU 559 2 93.4 1 734 B ALA 560 2 91.9 1 735 B LYS 561 2 89.5 1 736 B ASP 562 2 88.9 1 737 B LYS 563 2 84.6 1 738 B ARG 564 2 84.0 1 739 B PHE 565 2 84.7 1 740 B GLY 566 2 88.8 1 741 B LEU 567 2 91.2 1 742 B LEU 568 2 92.5 1 743 B LEU 569 2 92.4 1 744 B LYS 570 2 92.0 1 745 B GLU 571 2 92.2 1 746 B THR 572 2 91.9 1 747 B GLN 573 2 90.1 1 748 B PRO 574 2 87.9 1 749 B MET 575 2 85.7 1 750 B LYS 576 2 79.5 1 751 B GLN 577 2 64.0 1 752 B LYS 578 2 56.4 1 753 B SER 579 2 40.1 1 754 B VAL 580 2 37.4 1 755 B GLU 581 2 32.2 1 756 B THR 582 2 32.0 1 757 B SER 583 2 30.1 1 758 B ASN 584 2 33.0 1 759 B GLY 585 2 28.7 1 760 B GLY 586 2 25.5 1 761 B VAL 587 2 26.5 1 762 B GLU 588 2 24.9 1 763 B GLU 589 2 27.6 1 764 B THR 590 2 30.5 1 765 B MET 591 2 27.2 1 766 B LYS 592 2 26.0 1 767 B MET 593 2 35.0 1 768 loop_ _entity_poly_seq.entity_id _entity_poly_seq.num _entity_poly_seq.mon_id _entity_poly_seq.hetero 1 1 MET n 1 2 PRO n 1 3 SER n 1 4 LYS n 1 5 ASN n 1 6 SER n 1 7 ILE n 1 8 ASN n 1 9 ARG n 1 10 PRO n 1 11 LYS n 1 12 LEU n 1 13 THR n 1 14 SER n 1 15 ASN n 1 16 LEU n 1 17 HIS n 1 18 HIS n 1 19 LYS n 1 20 VAL n 1 21 HIS n 1 22 SER n 1 23 LEU n 1 24 ASN n 1 25 LYS n 1 26 LYS n 1 27 ARG n 1 28 ALA n 1 29 GLN n 1 30 ARG n 1 31 GLU n 1 32 ARG n 1 33 ALA n 1 34 GLY n 1 35 LEU n 1 36 LEU n 1 37 LYS n 1 38 PRO n 1 39 ALA n 1 40 ARG n 1 41 SER n 1 42 SER n 1 43 VAL n 1 44 ASN n 1 45 SER n 1 46 LYS n 1 47 SER n 1 48 GLY n 1 49 GLU n 1 50 ILE n 1 51 LYS n 1 52 SER n 1 53 VAL n 1 54 ALA n 1 55 LEU n 1 56 ASP n 1 57 LEU n 1 58 TYR n 1 59 PHE n 1 60 GLN n 1 61 ASN n 1 62 LYS n 1 63 LYS n 1 64 ASN n 1 65 GLU n 1 66 SER n 1 67 GLN n 1 68 ASN n 1 69 SER n 1 70 THR n 1 71 ALA n 1 72 VAL n 1 73 THR n 1 74 LEU n 1 75 GLN n 1 76 ASN n 1 77 ALA n 1 78 SER n 1 79 SER n 1 80 SER n 1 81 PRO n 1 82 ALA n 1 83 SER n 1 84 ILE n 1 85 THR n 1 86 THR n 1 87 ARG n 1 88 THR n 1 89 LEU n 1 90 SER n 1 91 LYS n 1 92 LYS n 1 93 ARG n 1 94 ALA n 1 95 LYS n 1 96 LYS n 1 97 ILE n 1 98 GLU n 1 99 ARG n 1 100 ASN n 1 101 LEU n 1 102 LYS n 1 103 TYR n 1 104 ALA n 1 105 THR n 1 106 GLN n 1 107 ARG n 1 108 LYS n 1 109 LEU n 1 110 LEU n 1 111 VAL n 1 112 ASP n 1 113 ALA n 1 114 SER n 1 115 ALA n 1 116 LYS n 1 117 LEU n 1 118 GLU n 1 119 ASP n 1 120 GLU n 1 121 MET n 1 122 ASP n 1 123 ILE n 1 124 ASP n 1 125 LEU n 1 126 ASP n 1 127 GLY n 1 128 GLY n 1 129 LYS n 1 130 LYS n 1 131 VAL n 1 132 LYS n 1 133 GLU n 1 134 ASN n 1 135 GLU n 1 136 LYS n 1 137 LYS n 1 138 SER n 1 139 SER n 1 140 LEU n 1 141 THR n 1 142 LEU n 1 143 VAL n 1 144 LYS n 1 145 GLU n 1 146 ALA n 1 147 LEU n 1 148 TRP n 1 149 SER n 1 150 VAL n 1 151 ILE n 1 152 ASP n 1 153 ASP n 1 154 THR n 1 155 ALA n 1 156 SER n 1 157 GLN n 1 158 GLY n 1 159 LEU n 1 160 ILE n 1 161 ILE n 1 162 GLU n 1 163 ASN n 1 164 GLY n 1 165 GLN n 1 166 GLY n 1 167 THR n 1 168 THR n 1 169 LEU n 1 170 GLY n 1 171 GLY n 1 172 PRO n 1 173 PHE n 1 174 PHE n 1 175 PRO n 2 1 MET n 2 2 ALA n 2 3 LEU n 2 4 ALA n 2 5 ILE n 2 6 SER n 2 7 HIS n 2 8 GLU n 2 9 ASP n 2 10 THR n 2 11 GLN n 2 12 ILE n 2 13 LEU n 2 14 LEU n 2 15 LYS n 2 16 ASP n 2 17 LYS n 2 18 ASN n 2 19 ILE n 2 20 LEU n 2 21 GLN n 2 22 GLU n 2 23 SER n 2 24 VAL n 2 25 LEU n 2 26 ASN n 2 27 LYS n 2 28 TYR n 2 29 ARG n 2 30 THR n 2 31 ALA n 2 32 GLY n 2 33 GLN n 2 34 ILE n 2 35 ALA n 2 36 GLN n 2 37 THR n 2 38 ALA n 2 39 LEU n 2 40 LYS n 2 41 TYR n 2 42 VAL n 2 43 THR n 2 44 SER n 2 45 LEU n 2 46 ILE n 2 47 ASN n 2 48 ASP n 2 49 SER n 2 50 TYR n 2 51 HIS n 2 52 SER n 2 53 LYS n 2 54 THR n 2 55 THR n 2 56 GLN n 2 57 ARG n 2 58 GLN n 2 59 LEU n 2 60 THR n 2 61 VAL n 2 62 PRO n 2 63 GLU n 2 64 LEU n 2 65 CYS n 2 66 LEU n 2 67 LEU n 2 68 THR n 2 69 ASP n 2 70 SER n 2 71 PHE n 2 72 ILE n 2 73 LEU n 2 74 THR n 2 75 ARG n 2 76 LEU n 2 77 GLU n 2 78 GLN n 2 79 TYR n 2 80 TYR n 2 81 LYS n 2 82 ASN n 2 83 LYS n 2 84 VAL n 2 85 ASN n 2 86 GLU n 2 87 ARG n 2 88 GLY n 2 89 ILE n 2 90 ALA n 2 91 ILE n 2 92 PRO n 2 93 THR n 2 94 THR n 2 95 ILE n 2 96 ASP n 2 97 ILE n 2 98 ASP n 2 99 GLN n 2 100 ILE n 2 101 SER n 2 102 GLY n 2 103 GLY n 2 104 TRP n 2 105 CYS n 2 106 PRO n 2 107 GLU n 2 108 ILE n 2 109 ASP n 2 110 ASP n 2 111 THR n 2 112 GLN n 2 113 ASN n 2 114 LEU n 2 115 LEU n 2 116 ASN n 2 117 TRP n 2 118 ASN n 2 119 LYS n 2 120 GLY n 2 121 LYS n 2 122 ASP n 2 123 SER n 2 124 THR n 2 125 PHE n 2 126 ALA n 2 127 SER n 2 128 SER n 2 129 VAL n 2 130 THR n 2 131 GLY n 2 132 THR n 2 133 LEU n 2 134 ARG n 2 135 PRO n 2 136 GLY n 2 137 ASP n 2 138 LEU n 2 139 VAL n 2 140 LYS n 2 141 ILE n 2 142 THR n 2 143 LEU n 2 144 GLY n 2 145 VAL n 2 146 HIS n 2 147 ILE n 2 148 ASP n 2 149 GLY n 2 150 TYR n 2 151 THR n 2 152 SER n 2 153 GLU n 2 154 VAL n 2 155 SER n 2 156 HIS n 2 157 THR n 2 158 MET n 2 159 VAL n 2 160 ILE n 2 161 TYR n 2 162 PRO n 2 163 VAL n 2 164 ASP n 2 165 GLU n 2 166 THR n 2 167 LYS n 2 168 PRO n 2 169 ILE n 2 170 PRO n 2 171 GLN n 2 172 PRO n 2 173 THR n 2 174 GLY n 2 175 PRO n 2 176 LEU n 2 177 LEU n 2 178 GLY n 2 179 GLY n 2 180 LYS n 2 181 ALA n 2 182 ASP n 2 183 ALA n 2 184 VAL n 2 185 ALA n 2 186 ALA n 2 187 ALA n 2 188 HIS n 2 189 ILE n 2 190 ALA n 2 191 MET n 2 192 GLU n 2 193 THR n 2 194 VAL n 2 195 VAL n 2 196 ALA n 2 197 LEU n 2 198 LEU n 2 199 ALA n 2 200 CYS n 2 201 ALA n 2 202 LEU n 2 203 THR n 2 204 PRO n 2 205 GLU n 2 206 LYS n 2 207 LEU n 2 208 PRO n 2 209 ALA n 2 210 SER n 2 211 LEU n 2 212 GLY n 2 213 GLY n 2 214 THR n 2 215 SER n 2 216 SER n 2 217 GLY n 2 218 ILE n 2 219 THR n 2 220 GLY n 2 221 GLN n 2 222 LEU n 2 223 ILE n 2 224 ARG n 2 225 THR n 2 226 ILE n 2 227 VAL n 2 228 ASP n 2 229 THR n 2 230 ILE n 2 231 ALA n 2 232 ARG n 2 233 SER n 2 234 TYR n 2 235 ASN n 2 236 CYS n 2 237 GLY n 2 238 VAL n 2 239 VAL n 2 240 PRO n 2 241 GLY n 2 242 SER n 2 243 ARG n 2 244 VAL n 2 245 ARG n 2 246 ARG n 2 247 ILE n 2 248 ARG n 2 249 ARG n 2 250 PHE n 2 251 LEU n 2 252 ALA n 2 253 GLY n 2 254 GLN n 2 255 ASN n 2 256 GLU n 2 257 GLY n 2 258 ILE n 2 259 VAL n 2 260 ALA n 2 261 GLU n 2 262 ARG n 2 263 GLU n 2 264 TYR n 2 265 LYS n 2 266 GLY n 2 267 VAL n 2 268 VAL n 2 269 TRP n 2 270 THR n 2 271 GLU n 2 272 SER n 2 273 HIS n 2 274 GLN n 2 275 GLU n 2 276 ALA n 2 277 ASP n 2 278 LEU n 2 279 LEU n 2 280 SER n 2 281 ASN n 2 282 THR n 2 283 ASP n 2 284 ALA n 2 285 LYS n 2 286 ASP n 2 287 LEU n 2 288 THR n 2 289 VAL n 2 290 VAL n 2 291 ASP n 2 292 ARG n 2 293 GLY n 2 294 GLN n 2 295 SER n 2 296 THR n 2 297 PRO n 2 298 PHE n 2 299 THR n 2 300 ASN n 2 301 VAL n 2 302 SER n 2 303 ALA n 2 304 ILE n 2 305 PRO n 2 306 SER n 2 307 ASP n 2 308 ASP n 2 309 PHE n 2 310 VAL n 2 311 VAL n 2 312 GLN n 2 313 SER n 2 314 GLY n 2 315 GLU n 2 316 VAL n 2 317 TYR n 2 318 LEU n 2 319 ILE n 2 320 ASP n 2 321 LEU n 2 322 LYS n 2 323 MET n 2 324 ALA n 2 325 SER n 2 326 LEU n 2 327 GLU n 2 328 HIS n 2 329 CYS n 2 330 THR n 2 331 LYS n 2 332 LYS n 2 333 GLY n 2 334 LEU n 2 335 VAL n 2 336 THR n 2 337 LEU n 2 338 GLU n 2 339 THR n 2 340 VAL n 2 341 ASP n 2 342 SER n 2 343 TYR n 2 344 THR n 2 345 GLY n 2 346 LYS n 2 347 SER n 2 348 HIS n 2 349 LYS n 2 350 ALA n 2 351 GLY n 2 352 GLU n 2 353 LEU n 2 354 ILE n 2 355 ALA n 2 356 ARG n 2 357 PRO n 2 358 GLY n 2 359 ALA n 2 360 TYR n 2 361 VAL n 2 362 ARG n 2 363 ASP n 2 364 PHE n 2 365 ALA n 2 366 GLN n 2 367 THR n 2 368 HIS n 2 369 ILE n 2 370 LEU n 2 371 LYS n 2 372 LEU n 2 373 LYS n 2 374 THR n 2 375 SER n 2 376 ARG n 2 377 GLN n 2 378 LEU n 2 379 LEU n 2 380 THR n 2 381 LYS n 2 382 ILE n 2 383 ASP n 2 384 LYS n 2 385 GLN n 2 386 GLY n 2 387 VAL n 2 388 TYR n 2 389 PRO n 2 390 PHE n 2 391 LYS n 2 392 LEU n 2 393 SER n 2 394 HIS n 2 395 LEU n 2 396 SER n 2 397 SER n 2 398 ASN n 2 399 PHE n 2 400 PRO n 2 401 PHE n 2 402 VAL n 2 403 HIS n 2 404 GLU n 2 405 ASN n 2 406 GLU n 2 407 GLU n 2 408 GLU n 2 409 LEU n 2 410 GLN n 2 411 SER n 2 412 LEU n 2 413 LYS n 2 414 LYS n 2 415 ASP n 2 416 LEU n 2 417 LYS n 2 418 SER n 2 419 PHE n 2 420 ARG n 2 421 LEU n 2 422 GLY n 2 423 MET n 2 424 SER n 2 425 GLU n 2 426 ILE n 2 427 SER n 2 428 ASN n 2 429 ASN n 2 430 TYR n 2 431 LEU n 2 432 CYS n 2 433 VAL n 2 434 GLU n 2 435 SER n 2 436 PRO n 2 437 ILE n 2 438 GLN n 2 439 ILE n 2 440 ALA n 2 441 ARG n 2 442 TRP n 2 443 VAL n 2 444 PRO n 2 445 TRP n 2 446 ASP n 2 447 HIS n 2 448 ILE n 2 449 LEU n 2 450 LYS n 2 451 ALA n 2 452 THR n 2 453 ASN n 2 454 PRO n 2 455 ASN n 2 456 GLY n 2 457 ASN n 2 458 LEU n 2 459 SER n 2 460 TYR n 2 461 ASP n 2 462 ALA n 2 463 THR n 2 464 SER n 2 465 THR n 2 466 LEU n 2 467 THR n 2 468 LEU n 2 469 PRO n 2 470 GLY n 2 471 HIS n 2 472 GLU n 2 473 LEU n 2 474 PRO n 2 475 LEU n 2 476 PRO n 2 477 LYS n 2 478 LEU n 2 479 GLY n 2 480 VAL n 2 481 SER n 2 482 ALA n 2 483 ILE n 2 484 LYS n 2 485 LEU n 2 486 LYS n 2 487 SER n 2 488 LEU n 2 489 MET n 2 490 ASN n 2 491 SER n 2 492 THR n 2 493 LYS n 2 494 GLU n 2 495 SER n 2 496 ILE n 2 497 SER n 2 498 LEU n 2 499 PRO n 2 500 VAL n 2 501 ALA n 2 502 ARG n 2 503 GLU n 2 504 CYS n 2 505 ASN n 2 506 THR n 2 507 ILE n 2 508 VAL n 2 509 LEU n 2 510 CYS n 2 511 ASP n 2 512 SER n 2 513 SER n 2 514 VAL n 2 515 SER n 2 516 THR n 2 517 THR n 2 518 ASP n 2 519 ARG n 2 520 PRO n 2 521 GLU n 2 522 LEU n 2 523 LEU n 2 524 ARG n 2 525 LEU n 2 526 THR n 2 527 GLY n 2 528 GLY n 2 529 SER n 2 530 LYS n 2 531 THR n 2 532 CYS n 2 533 GLN n 2 534 PRO n 2 535 SER n 2 536 TRP n 2 537 ILE n 2 538 HIS n 2 539 SER n 2 540 GLN n 2 541 HIS n 2 542 GLU n 2 543 LEU n 2 544 ASN n 2 545 PRO n 2 546 GLN n 2 547 ASP n 2 548 SER n 2 549 ILE n 2 550 VAL n 2 551 GLN n 2 552 GLY n 2 553 ILE n 2 554 PHE n 2 555 GLN n 2 556 LEU n 2 557 ALA n 2 558 THR n 2 559 LEU n 2 560 ALA n 2 561 LYS n 2 562 ASP n 2 563 LYS n 2 564 ARG n 2 565 PHE n 2 566 GLY n 2 567 LEU n 2 568 LEU n 2 569 LEU n 2 570 LYS n 2 571 GLU n 2 572 THR n 2 573 GLN n 2 574 PRO n 2 575 MET n 2 576 LYS n 2 577 GLN n 2 578 LYS n 2 579 SER n 2 580 VAL n 2 581 GLU n 2 582 THR n 2 583 SER n 2 584 ASN n 2 585 GLY n 2 586 GLY n 2 587 VAL n 2 588 GLU n 2 589 GLU n 2 590 THR n 2 591 MET n 2 592 LYS n 2 593 MET n loop_ _entity.id _entity.type _entity.src_method _entity.pdbx_description _entity.formula_weight _entity.pdbx_number_of_molecules _entity.pdbx_ec _entity.pdbx_mutation _entity.pdbx_fragment _entity.details 1 polymer man "ALB1" 19322.037 1 ? ? ? ? 2 polymer man "ARX1" 65274.297 1 ? ? ? ? loop_ _pdbx_poly_seq_scheme.asym_id _pdbx_poly_seq_scheme.entity_id _pdbx_poly_seq_scheme.seq_id _pdbx_poly_seq_scheme.mon_id _pdbx_poly_seq_scheme.ndb_seq_num _pdbx_poly_seq_scheme.pdb_seq_num _pdbx_poly_seq_scheme.auth_seq_num _pdbx_poly_seq_scheme.pdb_mon_id _pdbx_poly_seq_scheme.auth_mon_id _pdbx_poly_seq_scheme.pdb_strand_id _pdbx_poly_seq_scheme.pdb_ins_code _pdbx_poly_seq_scheme.hetero A 1 1 MET 1 1 1 MET MET A . n A 1 2 PRO 2 2 2 PRO PRO A . n A 1 3 SER 3 3 3 SER SER A . n A 1 4 LYS 4 4 4 LYS LYS A . n A 1 5 ASN 5 5 5 ASN ASN A . n A 1 6 SER 6 6 6 SER SER A . n A 1 7 ILE 7 7 7 ILE ILE A . n A 1 8 ASN 8 8 8 ASN ASN A . n A 1 9 ARG 9 9 9 ARG ARG A . n A 1 10 PRO 10 10 10 PRO PRO A . n A 1 11 LYS 11 11 11 LYS LYS A . n A 1 12 LEU 12 12 12 LEU LEU A . n A 1 13 THR 13 13 13 THR THR A . n A 1 14 SER 14 14 14 SER SER A . n A 1 15 ASN 15 15 15 ASN ASN A . n A 1 16 LEU 16 16 16 LEU LEU A . n A 1 17 HIS 17 17 17 HIS HIS A . n A 1 18 HIS 18 18 18 HIS HIS A . n A 1 19 LYS 19 19 19 LYS LYS A . n A 1 20 VAL 20 20 20 VAL VAL A . n A 1 21 HIS 21 21 21 HIS HIS A . n A 1 22 SER 22 22 22 SER SER A . n A 1 23 LEU 23 23 23 LEU LEU A . n A 1 24 ASN 24 24 24 ASN ASN A . n A 1 25 LYS 25 25 25 LYS LYS A . n A 1 26 LYS 26 26 26 LYS LYS A . n A 1 27 ARG 27 27 27 ARG ARG A . n A 1 28 ALA 28 28 28 ALA ALA A . n A 1 29 GLN 29 29 29 GLN GLN A . n A 1 30 ARG 30 30 30 ARG ARG A . n A 1 31 GLU 31 31 31 GLU GLU A . n A 1 32 ARG 32 32 32 ARG ARG A . n A 1 33 ALA 33 33 33 ALA ALA A . n A 1 34 GLY 34 34 34 GLY GLY A . n A 1 35 LEU 35 35 35 LEU LEU A . n A 1 36 LEU 36 36 36 LEU LEU A . n A 1 37 LYS 37 37 37 LYS LYS A . n A 1 38 PRO 38 38 38 PRO PRO A . n A 1 39 ALA 39 39 39 ALA ALA A . n A 1 40 ARG 40 40 40 ARG ARG A . n A 1 41 SER 41 41 41 SER SER A . n A 1 42 SER 42 42 42 SER SER A . n A 1 43 VAL 43 43 43 VAL VAL A . n A 1 44 ASN 44 44 44 ASN ASN A . n A 1 45 SER 45 45 45 SER SER A . n A 1 46 LYS 46 46 46 LYS LYS A . n A 1 47 SER 47 47 47 SER SER A . n A 1 48 GLY 48 48 48 GLY GLY A . n A 1 49 GLU 49 49 49 GLU GLU A . n A 1 50 ILE 50 50 50 ILE ILE A . n A 1 51 LYS 51 51 51 LYS LYS A . n A 1 52 SER 52 52 52 SER SER A . n A 1 53 VAL 53 53 53 VAL VAL A . n A 1 54 ALA 54 54 54 ALA ALA A . n A 1 55 LEU 55 55 55 LEU LEU A . n A 1 56 ASP 56 56 56 ASP ASP A . n A 1 57 LEU 57 57 57 LEU LEU A . n A 1 58 TYR 58 58 58 TYR TYR A . n A 1 59 PHE 59 59 59 PHE PHE A . n A 1 60 GLN 60 60 60 GLN GLN A . n A 1 61 ASN 61 61 61 ASN ASN A . n A 1 62 LYS 62 62 62 LYS LYS A . n A 1 63 LYS 63 63 63 LYS LYS A . n A 1 64 ASN 64 64 64 ASN ASN A . n A 1 65 GLU 65 65 65 GLU GLU A . n A 1 66 SER 66 66 66 SER SER A . n A 1 67 GLN 67 67 67 GLN GLN A . n A 1 68 ASN 68 68 68 ASN ASN A . n A 1 69 SER 69 69 69 SER SER A . n A 1 70 THR 70 70 70 THR THR A . n A 1 71 ALA 71 71 71 ALA ALA A . n A 1 72 VAL 72 72 72 VAL VAL A . n A 1 73 THR 73 73 73 THR THR A . n A 1 74 LEU 74 74 74 LEU LEU A . n A 1 75 GLN 75 75 75 GLN GLN A . n A 1 76 ASN 76 76 76 ASN ASN A . n A 1 77 ALA 77 77 77 ALA ALA A . n A 1 78 SER 78 78 78 SER SER A . n A 1 79 SER 79 79 79 SER SER A . n A 1 80 SER 80 80 80 SER SER A . n A 1 81 PRO 81 81 81 PRO PRO A . n A 1 82 ALA 82 82 82 ALA ALA A . n A 1 83 SER 83 83 83 SER SER A . n A 1 84 ILE 84 84 84 ILE ILE A . n A 1 85 THR 85 85 85 THR THR A . n A 1 86 THR 86 86 86 THR THR A . n A 1 87 ARG 87 87 87 ARG ARG A . n A 1 88 THR 88 88 88 THR THR A . n A 1 89 LEU 89 89 89 LEU LEU A . n A 1 90 SER 90 90 90 SER SER A . n A 1 91 LYS 91 91 91 LYS LYS A . n A 1 92 LYS 92 92 92 LYS LYS A . n A 1 93 ARG 93 93 93 ARG ARG A . n A 1 94 ALA 94 94 94 ALA ALA A . n A 1 95 LYS 95 95 95 LYS LYS A . n A 1 96 LYS 96 96 96 LYS LYS A . n A 1 97 ILE 97 97 97 ILE ILE A . n A 1 98 GLU 98 98 98 GLU GLU A . n A 1 99 ARG 99 99 99 ARG ARG A . n A 1 100 ASN 100 100 100 ASN ASN A . n A 1 101 LEU 101 101 101 LEU LEU A . n A 1 102 LYS 102 102 102 LYS LYS A . n A 1 103 TYR 103 103 103 TYR TYR A . n A 1 104 ALA 104 104 104 ALA ALA A . n A 1 105 THR 105 105 105 THR THR A . n A 1 106 GLN 106 106 106 GLN GLN A . n A 1 107 ARG 107 107 107 ARG ARG A . n A 1 108 LYS 108 108 108 LYS LYS A . n A 1 109 LEU 109 109 109 LEU LEU A . n A 1 110 LEU 110 110 110 LEU LEU A . n A 1 111 VAL 111 111 111 VAL VAL A . n A 1 112 ASP 112 112 112 ASP ASP A . n A 1 113 ALA 113 113 113 ALA ALA A . n A 1 114 SER 114 114 114 SER SER A . n A 1 115 ALA 115 115 115 ALA ALA A . n A 1 116 LYS 116 116 116 LYS LYS A . n A 1 117 LEU 117 117 117 LEU LEU A . n A 1 118 GLU 118 118 118 GLU GLU A . n A 1 119 ASP 119 119 119 ASP ASP A . n A 1 120 GLU 120 120 120 GLU GLU A . n A 1 121 MET 121 121 121 MET MET A . n A 1 122 ASP 122 122 122 ASP ASP A . n A 1 123 ILE 123 123 123 ILE ILE A . n A 1 124 ASP 124 124 124 ASP ASP A . n A 1 125 LEU 125 125 125 LEU LEU A . n A 1 126 ASP 126 126 126 ASP ASP A . n A 1 127 GLY 127 127 127 GLY GLY A . n A 1 128 GLY 128 128 128 GLY GLY A . n A 1 129 LYS 129 129 129 LYS LYS A . n A 1 130 LYS 130 130 130 LYS LYS A . n A 1 131 VAL 131 131 131 VAL VAL A . n A 1 132 LYS 132 132 132 LYS LYS A . n A 1 133 GLU 133 133 133 GLU GLU A . n A 1 134 ASN 134 134 134 ASN ASN A . n A 1 135 GLU 135 135 135 GLU GLU A . n A 1 136 LYS 136 136 136 LYS LYS A . n A 1 137 LYS 137 137 137 LYS LYS A . n A 1 138 SER 138 138 138 SER SER A . n A 1 139 SER 139 139 139 SER SER A . n A 1 140 LEU 140 140 140 LEU LEU A . n A 1 141 THR 141 141 141 THR THR A . n A 1 142 LEU 142 142 142 LEU LEU A . n A 1 143 VAL 143 143 143 VAL VAL A . n A 1 144 LYS 144 144 144 LYS LYS A . n A 1 145 GLU 145 145 145 GLU GLU A . n A 1 146 ALA 146 146 146 ALA ALA A . n A 1 147 LEU 147 147 147 LEU LEU A . n A 1 148 TRP 148 148 148 TRP TRP A . n A 1 149 SER 149 149 149 SER SER A . n A 1 150 VAL 150 150 150 VAL VAL A . n A 1 151 ILE 151 151 151 ILE ILE A . n A 1 152 ASP 152 152 152 ASP ASP A . n A 1 153 ASP 153 153 153 ASP ASP A . n A 1 154 THR 154 154 154 THR THR A . n A 1 155 ALA 155 155 155 ALA ALA A . n A 1 156 SER 156 156 156 SER SER A . n A 1 157 GLN 157 157 157 GLN GLN A . n A 1 158 GLY 158 158 158 GLY GLY A . n A 1 159 LEU 159 159 159 LEU LEU A . n A 1 160 ILE 160 160 160 ILE ILE A . n A 1 161 ILE 161 161 161 ILE ILE A . n A 1 162 GLU 162 162 162 GLU GLU A . n A 1 163 ASN 163 163 163 ASN ASN A . n A 1 164 GLY 164 164 164 GLY GLY A . n A 1 165 GLN 165 165 165 GLN GLN A . n A 1 166 GLY 166 166 166 GLY GLY A . n A 1 167 THR 167 167 167 THR THR A . n A 1 168 THR 168 168 168 THR THR A . n A 1 169 LEU 169 169 169 LEU LEU A . n A 1 170 GLY 170 170 170 GLY GLY A . n A 1 171 GLY 171 171 171 GLY GLY A . n A 1 172 PRO 172 172 172 PRO PRO A . n A 1 173 PHE 173 173 173 PHE PHE A . n A 1 174 PHE 174 174 174 PHE PHE A . n A 1 175 PRO 175 175 175 PRO PRO A . n B 2 1 MET 1 1 1 MET MET B . n B 2 2 ALA 2 2 2 ALA ALA B . n B 2 3 LEU 3 3 3 LEU LEU B . n B 2 4 ALA 4 4 4 ALA ALA B . n B 2 5 ILE 5 5 5 ILE ILE B . n B 2 6 SER 6 6 6 SER SER B . n B 2 7 HIS 7 7 7 HIS HIS B . n B 2 8 GLU 8 8 8 GLU GLU B . n B 2 9 ASP 9 9 9 ASP ASP B . n B 2 10 THR 10 10 10 THR THR B . n B 2 11 GLN 11 11 11 GLN GLN B . n B 2 12 ILE 12 12 12 ILE ILE B . n B 2 13 LEU 13 13 13 LEU LEU B . n B 2 14 LEU 14 14 14 LEU LEU B . n B 2 15 LYS 15 15 15 LYS LYS B . n B 2 16 ASP 16 16 16 ASP ASP B . n B 2 17 LYS 17 17 17 LYS LYS B . n B 2 18 ASN 18 18 18 ASN ASN B . n B 2 19 ILE 19 19 19 ILE ILE B . n B 2 20 LEU 20 20 20 LEU LEU B . n B 2 21 GLN 21 21 21 GLN GLN B . n B 2 22 GLU 22 22 22 GLU GLU B . n B 2 23 SER 23 23 23 SER SER B . n B 2 24 VAL 24 24 24 VAL VAL B . n B 2 25 LEU 25 25 25 LEU LEU B . n B 2 26 ASN 26 26 26 ASN ASN B . n B 2 27 LYS 27 27 27 LYS LYS B . n B 2 28 TYR 28 28 28 TYR TYR B . n B 2 29 ARG 29 29 29 ARG ARG B . n B 2 30 THR 30 30 30 THR THR B . n B 2 31 ALA 31 31 31 ALA ALA B . n B 2 32 GLY 32 32 32 GLY GLY B . n B 2 33 GLN 33 33 33 GLN GLN B . n B 2 34 ILE 34 34 34 ILE ILE B . n B 2 35 ALA 35 35 35 ALA ALA B . n B 2 36 GLN 36 36 36 GLN GLN B . n B 2 37 THR 37 37 37 THR THR B . n B 2 38 ALA 38 38 38 ALA ALA B . n B 2 39 LEU 39 39 39 LEU LEU B . n B 2 40 LYS 40 40 40 LYS LYS B . n B 2 41 TYR 41 41 41 TYR TYR B . n B 2 42 VAL 42 42 42 VAL VAL B . n B 2 43 THR 43 43 43 THR THR B . n B 2 44 SER 44 44 44 SER SER B . n B 2 45 LEU 45 45 45 LEU LEU B . n B 2 46 ILE 46 46 46 ILE ILE B . n B 2 47 ASN 47 47 47 ASN ASN B . n B 2 48 ASP 48 48 48 ASP ASP B . n B 2 49 SER 49 49 49 SER SER B . n B 2 50 TYR 50 50 50 TYR TYR B . n B 2 51 HIS 51 51 51 HIS HIS B . n B 2 52 SER 52 52 52 SER SER B . n B 2 53 LYS 53 53 53 LYS LYS B . n B 2 54 THR 54 54 54 THR THR B . n B 2 55 THR 55 55 55 THR THR B . n B 2 56 GLN 56 56 56 GLN GLN B . n B 2 57 ARG 57 57 57 ARG ARG B . n B 2 58 GLN 58 58 58 GLN GLN B . n B 2 59 LEU 59 59 59 LEU LEU B . n B 2 60 THR 60 60 60 THR THR B . n B 2 61 VAL 61 61 61 VAL VAL B . n B 2 62 PRO 62 62 62 PRO PRO B . n B 2 63 GLU 63 63 63 GLU GLU B . n B 2 64 LEU 64 64 64 LEU LEU B . n B 2 65 CYS 65 65 65 CYS CYS B . n B 2 66 LEU 66 66 66 LEU LEU B . n B 2 67 LEU 67 67 67 LEU LEU B . n B 2 68 THR 68 68 68 THR THR B . n B 2 69 ASP 69 69 69 ASP ASP B . n B 2 70 SER 70 70 70 SER SER B . n B 2 71 PHE 71 71 71 PHE PHE B . n B 2 72 ILE 72 72 72 ILE ILE B . n B 2 73 LEU 73 73 73 LEU LEU B . n B 2 74 THR 74 74 74 THR THR B . n B 2 75 ARG 75 75 75 ARG ARG B . n B 2 76 LEU 76 76 76 LEU LEU B . n B 2 77 GLU 77 77 77 GLU GLU B . n B 2 78 GLN 78 78 78 GLN GLN B . n B 2 79 TYR 79 79 79 TYR TYR B . n B 2 80 TYR 80 80 80 TYR TYR B . n B 2 81 LYS 81 81 81 LYS LYS B . n B 2 82 ASN 82 82 82 ASN ASN B . n B 2 83 LYS 83 83 83 LYS LYS B . n B 2 84 VAL 84 84 84 VAL VAL B . n B 2 85 ASN 85 85 85 ASN ASN B . n B 2 86 GLU 86 86 86 GLU GLU B . n B 2 87 ARG 87 87 87 ARG ARG B . n B 2 88 GLY 88 88 88 GLY GLY B . n B 2 89 ILE 89 89 89 ILE ILE B . n B 2 90 ALA 90 90 90 ALA ALA B . n B 2 91 ILE 91 91 91 ILE ILE B . n B 2 92 PRO 92 92 92 PRO PRO B . n B 2 93 THR 93 93 93 THR THR B . n B 2 94 THR 94 94 94 THR THR B . n B 2 95 ILE 95 95 95 ILE ILE B . n B 2 96 ASP 96 96 96 ASP ASP B . n B 2 97 ILE 97 97 97 ILE ILE B . n B 2 98 ASP 98 98 98 ASP ASP B . n B 2 99 GLN 99 99 99 GLN GLN B . n B 2 100 ILE 100 100 100 ILE ILE B . n B 2 101 SER 101 101 101 SER SER B . n B 2 102 GLY 102 102 102 GLY GLY B . n B 2 103 GLY 103 103 103 GLY GLY B . n B 2 104 TRP 104 104 104 TRP TRP B . n B 2 105 CYS 105 105 105 CYS CYS B . n B 2 106 PRO 106 106 106 PRO PRO B . n B 2 107 GLU 107 107 107 GLU GLU B . n B 2 108 ILE 108 108 108 ILE ILE B . n B 2 109 ASP 109 109 109 ASP ASP B . n B 2 110 ASP 110 110 110 ASP ASP B . n B 2 111 THR 111 111 111 THR THR B . n B 2 112 GLN 112 112 112 GLN GLN B . n B 2 113 ASN 113 113 113 ASN ASN B . n B 2 114 LEU 114 114 114 LEU LEU B . n B 2 115 LEU 115 115 115 LEU LEU B . n B 2 116 ASN 116 116 116 ASN ASN B . n B 2 117 TRP 117 117 117 TRP TRP B . n B 2 118 ASN 118 118 118 ASN ASN B . n B 2 119 LYS 119 119 119 LYS LYS B . n B 2 120 GLY 120 120 120 GLY GLY B . n B 2 121 LYS 121 121 121 LYS LYS B . n B 2 122 ASP 122 122 122 ASP ASP B . n B 2 123 SER 123 123 123 SER SER B . n B 2 124 THR 124 124 124 THR THR B . n B 2 125 PHE 125 125 125 PHE PHE B . n B 2 126 ALA 126 126 126 ALA ALA B . n B 2 127 SER 127 127 127 SER SER B . n B 2 128 SER 128 128 128 SER SER B . n B 2 129 VAL 129 129 129 VAL VAL B . n B 2 130 THR 130 130 130 THR THR B . n B 2 131 GLY 131 131 131 GLY GLY B . n B 2 132 THR 132 132 132 THR THR B . n B 2 133 LEU 133 133 133 LEU LEU B . n B 2 134 ARG 134 134 134 ARG ARG B . n B 2 135 PRO 135 135 135 PRO PRO B . n B 2 136 GLY 136 136 136 GLY GLY B . n B 2 137 ASP 137 137 137 ASP ASP B . n B 2 138 LEU 138 138 138 LEU LEU B . n B 2 139 VAL 139 139 139 VAL VAL B . n B 2 140 LYS 140 140 140 LYS LYS B . n B 2 141 ILE 141 141 141 ILE ILE B . n B 2 142 THR 142 142 142 THR THR B . n B 2 143 LEU 143 143 143 LEU LEU B . n B 2 144 GLY 144 144 144 GLY GLY B . n B 2 145 VAL 145 145 145 VAL VAL B . n B 2 146 HIS 146 146 146 HIS HIS B . n B 2 147 ILE 147 147 147 ILE ILE B . n B 2 148 ASP 148 148 148 ASP ASP B . n B 2 149 GLY 149 149 149 GLY GLY B . n B 2 150 TYR 150 150 150 TYR TYR B . n B 2 151 THR 151 151 151 THR THR B . n B 2 152 SER 152 152 152 SER SER B . n B 2 153 GLU 153 153 153 GLU GLU B . n B 2 154 VAL 154 154 154 VAL VAL B . n B 2 155 SER 155 155 155 SER SER B . n B 2 156 HIS 156 156 156 HIS HIS B . n B 2 157 THR 157 157 157 THR THR B . n B 2 158 MET 158 158 158 MET MET B . n B 2 159 VAL 159 159 159 VAL VAL B . n B 2 160 ILE 160 160 160 ILE ILE B . n B 2 161 TYR 161 161 161 TYR TYR B . n B 2 162 PRO 162 162 162 PRO PRO B . n B 2 163 VAL 163 163 163 VAL VAL B . n B 2 164 ASP 164 164 164 ASP ASP B . n B 2 165 GLU 165 165 165 GLU GLU B . n B 2 166 THR 166 166 166 THR THR B . n B 2 167 LYS 167 167 167 LYS LYS B . n B 2 168 PRO 168 168 168 PRO PRO B . n B 2 169 ILE 169 169 169 ILE ILE B . n B 2 170 PRO 170 170 170 PRO PRO B . n B 2 171 GLN 171 171 171 GLN GLN B . n B 2 172 PRO 172 172 172 PRO PRO B . n B 2 173 THR 173 173 173 THR THR B . n B 2 174 GLY 174 174 174 GLY GLY B . n B 2 175 PRO 175 175 175 PRO PRO B . n B 2 176 LEU 176 176 176 LEU LEU B . n B 2 177 LEU 177 177 177 LEU LEU B . n B 2 178 GLY 178 178 178 GLY GLY B . n B 2 179 GLY 179 179 179 GLY GLY B . n B 2 180 LYS 180 180 180 LYS LYS B . n B 2 181 ALA 181 181 181 ALA ALA B . n B 2 182 ASP 182 182 182 ASP ASP B . n B 2 183 ALA 183 183 183 ALA ALA B . n B 2 184 VAL 184 184 184 VAL VAL B . n B 2 185 ALA 185 185 185 ALA ALA B . n B 2 186 ALA 186 186 186 ALA ALA B . n B 2 187 ALA 187 187 187 ALA ALA B . n B 2 188 HIS 188 188 188 HIS HIS B . n B 2 189 ILE 189 189 189 ILE ILE B . n B 2 190 ALA 190 190 190 ALA ALA B . n B 2 191 MET 191 191 191 MET MET B . n B 2 192 GLU 192 192 192 GLU GLU B . n B 2 193 THR 193 193 193 THR THR B . n B 2 194 VAL 194 194 194 VAL VAL B . n B 2 195 VAL 195 195 195 VAL VAL B . n B 2 196 ALA 196 196 196 ALA ALA B . n B 2 197 LEU 197 197 197 LEU LEU B . n B 2 198 LEU 198 198 198 LEU LEU B . n B 2 199 ALA 199 199 199 ALA ALA B . n B 2 200 CYS 200 200 200 CYS CYS B . n B 2 201 ALA 201 201 201 ALA ALA B . n B 2 202 LEU 202 202 202 LEU LEU B . n B 2 203 THR 203 203 203 THR THR B . n B 2 204 PRO 204 204 204 PRO PRO B . n B 2 205 GLU 205 205 205 GLU GLU B . n B 2 206 LYS 206 206 206 LYS LYS B . n B 2 207 LEU 207 207 207 LEU LEU B . n B 2 208 PRO 208 208 208 PRO PRO B . n B 2 209 ALA 209 209 209 ALA ALA B . n B 2 210 SER 210 210 210 SER SER B . n B 2 211 LEU 211 211 211 LEU LEU B . n B 2 212 GLY 212 212 212 GLY GLY B . n B 2 213 GLY 213 213 213 GLY GLY B . n B 2 214 THR 214 214 214 THR THR B . n B 2 215 SER 215 215 215 SER SER B . n B 2 216 SER 216 216 216 SER SER B . n B 2 217 GLY 217 217 217 GLY GLY B . n B 2 218 ILE 218 218 218 ILE ILE B . n B 2 219 THR 219 219 219 THR THR B . n B 2 220 GLY 220 220 220 GLY GLY B . n B 2 221 GLN 221 221 221 GLN GLN B . n B 2 222 LEU 222 222 222 LEU LEU B . n B 2 223 ILE 223 223 223 ILE ILE B . n B 2 224 ARG 224 224 224 ARG ARG B . n B 2 225 THR 225 225 225 THR THR B . n B 2 226 ILE 226 226 226 ILE ILE B . n B 2 227 VAL 227 227 227 VAL VAL B . n B 2 228 ASP 228 228 228 ASP ASP B . n B 2 229 THR 229 229 229 THR THR B . n B 2 230 ILE 230 230 230 ILE ILE B . n B 2 231 ALA 231 231 231 ALA ALA B . n B 2 232 ARG 232 232 232 ARG ARG B . n B 2 233 SER 233 233 233 SER SER B . n B 2 234 TYR 234 234 234 TYR TYR B . n B 2 235 ASN 235 235 235 ASN ASN B . n B 2 236 CYS 236 236 236 CYS CYS B . n B 2 237 GLY 237 237 237 GLY GLY B . n B 2 238 VAL 238 238 238 VAL VAL B . n B 2 239 VAL 239 239 239 VAL VAL B . n B 2 240 PRO 240 240 240 PRO PRO B . n B 2 241 GLY 241 241 241 GLY GLY B . n B 2 242 SER 242 242 242 SER SER B . n B 2 243 ARG 243 243 243 ARG ARG B . n B 2 244 VAL 244 244 244 VAL VAL B . n B 2 245 ARG 245 245 245 ARG ARG B . n B 2 246 ARG 246 246 246 ARG ARG B . n B 2 247 ILE 247 247 247 ILE ILE B . n B 2 248 ARG 248 248 248 ARG ARG B . n B 2 249 ARG 249 249 249 ARG ARG B . n B 2 250 PHE 250 250 250 PHE PHE B . n B 2 251 LEU 251 251 251 LEU LEU B . n B 2 252 ALA 252 252 252 ALA ALA B . n B 2 253 GLY 253 253 253 GLY GLY B . n B 2 254 GLN 254 254 254 GLN GLN B . n B 2 255 ASN 255 255 255 ASN ASN B . n B 2 256 GLU 256 256 256 GLU GLU B . n B 2 257 GLY 257 257 257 GLY GLY B . n B 2 258 ILE 258 258 258 ILE ILE B . n B 2 259 VAL 259 259 259 VAL VAL B . n B 2 260 ALA 260 260 260 ALA ALA B . n B 2 261 GLU 261 261 261 GLU GLU B . n B 2 262 ARG 262 262 262 ARG ARG B . n B 2 263 GLU 263 263 263 GLU GLU B . n B 2 264 TYR 264 264 264 TYR TYR B . n B 2 265 LYS 265 265 265 LYS LYS B . n B 2 266 GLY 266 266 266 GLY GLY B . n B 2 267 VAL 267 267 267 VAL VAL B . n B 2 268 VAL 268 268 268 VAL VAL B . n B 2 269 TRP 269 269 269 TRP TRP B . n B 2 270 THR 270 270 270 THR THR B . n B 2 271 GLU 271 271 271 GLU GLU B . n B 2 272 SER 272 272 272 SER SER B . n B 2 273 HIS 273 273 273 HIS HIS B . n B 2 274 GLN 274 274 274 GLN GLN B . n B 2 275 GLU 275 275 275 GLU GLU B . n B 2 276 ALA 276 276 276 ALA ALA B . n B 2 277 ASP 277 277 277 ASP ASP B . n B 2 278 LEU 278 278 278 LEU LEU B . n B 2 279 LEU 279 279 279 LEU LEU B . n B 2 280 SER 280 280 280 SER SER B . n B 2 281 ASN 281 281 281 ASN ASN B . n B 2 282 THR 282 282 282 THR THR B . n B 2 283 ASP 283 283 283 ASP ASP B . n B 2 284 ALA 284 284 284 ALA ALA B . n B 2 285 LYS 285 285 285 LYS LYS B . n B 2 286 ASP 286 286 286 ASP ASP B . n B 2 287 LEU 287 287 287 LEU LEU B . n B 2 288 THR 288 288 288 THR THR B . n B 2 289 VAL 289 289 289 VAL VAL B . n B 2 290 VAL 290 290 290 VAL VAL B . n B 2 291 ASP 291 291 291 ASP ASP B . n B 2 292 ARG 292 292 292 ARG ARG B . n B 2 293 GLY 293 293 293 GLY GLY B . n B 2 294 GLN 294 294 294 GLN GLN B . n B 2 295 SER 295 295 295 SER SER B . n B 2 296 THR 296 296 296 THR THR B . n B 2 297 PRO 297 297 297 PRO PRO B . n B 2 298 PHE 298 298 298 PHE PHE B . n B 2 299 THR 299 299 299 THR THR B . n B 2 300 ASN 300 300 300 ASN ASN B . n B 2 301 VAL 301 301 301 VAL VAL B . n B 2 302 SER 302 302 302 SER SER B . n B 2 303 ALA 303 303 303 ALA ALA B . n B 2 304 ILE 304 304 304 ILE ILE B . n B 2 305 PRO 305 305 305 PRO PRO B . n B 2 306 SER 306 306 306 SER SER B . n B 2 307 ASP 307 307 307 ASP ASP B . n B 2 308 ASP 308 308 308 ASP ASP B . n B 2 309 PHE 309 309 309 PHE PHE B . n B 2 310 VAL 310 310 310 VAL VAL B . n B 2 311 VAL 311 311 311 VAL VAL B . n B 2 312 GLN 312 312 312 GLN GLN B . n B 2 313 SER 313 313 313 SER SER B . n B 2 314 GLY 314 314 314 GLY GLY B . n B 2 315 GLU 315 315 315 GLU GLU B . n B 2 316 VAL 316 316 316 VAL VAL B . n B 2 317 TYR 317 317 317 TYR TYR B . n B 2 318 LEU 318 318 318 LEU LEU B . n B 2 319 ILE 319 319 319 ILE ILE B . n B 2 320 ASP 320 320 320 ASP ASP B . n B 2 321 LEU 321 321 321 LEU LEU B . n B 2 322 LYS 322 322 322 LYS LYS B . n B 2 323 MET 323 323 323 MET MET B . n B 2 324 ALA 324 324 324 ALA ALA B . n B 2 325 SER 325 325 325 SER SER B . n B 2 326 LEU 326 326 326 LEU LEU B . n B 2 327 GLU 327 327 327 GLU GLU B . n B 2 328 HIS 328 328 328 HIS HIS B . n B 2 329 CYS 329 329 329 CYS CYS B . n B 2 330 THR 330 330 330 THR THR B . n B 2 331 LYS 331 331 331 LYS LYS B . n B 2 332 LYS 332 332 332 LYS LYS B . n B 2 333 GLY 333 333 333 GLY GLY B . n B 2 334 LEU 334 334 334 LEU LEU B . n B 2 335 VAL 335 335 335 VAL VAL B . n B 2 336 THR 336 336 336 THR THR B . n B 2 337 LEU 337 337 337 LEU LEU B . n B 2 338 GLU 338 338 338 GLU GLU B . n B 2 339 THR 339 339 339 THR THR B . n B 2 340 VAL 340 340 340 VAL VAL B . n B 2 341 ASP 341 341 341 ASP ASP B . n B 2 342 SER 342 342 342 SER SER B . n B 2 343 TYR 343 343 343 TYR TYR B . n B 2 344 THR 344 344 344 THR THR B . n B 2 345 GLY 345 345 345 GLY GLY B . n B 2 346 LYS 346 346 346 LYS LYS B . n B 2 347 SER 347 347 347 SER SER B . n B 2 348 HIS 348 348 348 HIS HIS B . n B 2 349 LYS 349 349 349 LYS LYS B . n B 2 350 ALA 350 350 350 ALA ALA B . n B 2 351 GLY 351 351 351 GLY GLY B . n B 2 352 GLU 352 352 352 GLU GLU B . n B 2 353 LEU 353 353 353 LEU LEU B . n B 2 354 ILE 354 354 354 ILE ILE B . n B 2 355 ALA 355 355 355 ALA ALA B . n B 2 356 ARG 356 356 356 ARG ARG B . n B 2 357 PRO 357 357 357 PRO PRO B . n B 2 358 GLY 358 358 358 GLY GLY B . n B 2 359 ALA 359 359 359 ALA ALA B . n B 2 360 TYR 360 360 360 TYR TYR B . n B 2 361 VAL 361 361 361 VAL VAL B . n B 2 362 ARG 362 362 362 ARG ARG B . n B 2 363 ASP 363 363 363 ASP ASP B . n B 2 364 PHE 364 364 364 PHE PHE B . n B 2 365 ALA 365 365 365 ALA ALA B . n B 2 366 GLN 366 366 366 GLN GLN B . n B 2 367 THR 367 367 367 THR THR B . n B 2 368 HIS 368 368 368 HIS HIS B . n B 2 369 ILE 369 369 369 ILE ILE B . n B 2 370 LEU 370 370 370 LEU LEU B . n B 2 371 LYS 371 371 371 LYS LYS B . n B 2 372 LEU 372 372 372 LEU LEU B . n B 2 373 LYS 373 373 373 LYS LYS B . n B 2 374 THR 374 374 374 THR THR B . n B 2 375 SER 375 375 375 SER SER B . n B 2 376 ARG 376 376 376 ARG ARG B . n B 2 377 GLN 377 377 377 GLN GLN B . n B 2 378 LEU 378 378 378 LEU LEU B . n B 2 379 LEU 379 379 379 LEU LEU B . n B 2 380 THR 380 380 380 THR THR B . n B 2 381 LYS 381 381 381 LYS LYS B . n B 2 382 ILE 382 382 382 ILE ILE B . n B 2 383 ASP 383 383 383 ASP ASP B . n B 2 384 LYS 384 384 384 LYS LYS B . n B 2 385 GLN 385 385 385 GLN GLN B . n B 2 386 GLY 386 386 386 GLY GLY B . n B 2 387 VAL 387 387 387 VAL VAL B . n B 2 388 TYR 388 388 388 TYR TYR B . n B 2 389 PRO 389 389 389 PRO PRO B . n B 2 390 PHE 390 390 390 PHE PHE B . n B 2 391 LYS 391 391 391 LYS LYS B . n B 2 392 LEU 392 392 392 LEU LEU B . n B 2 393 SER 393 393 393 SER SER B . n B 2 394 HIS 394 394 394 HIS HIS B . n B 2 395 LEU 395 395 395 LEU LEU B . n B 2 396 SER 396 396 396 SER SER B . n B 2 397 SER 397 397 397 SER SER B . n B 2 398 ASN 398 398 398 ASN ASN B . n B 2 399 PHE 399 399 399 PHE PHE B . n B 2 400 PRO 400 400 400 PRO PRO B . n B 2 401 PHE 401 401 401 PHE PHE B . n B 2 402 VAL 402 402 402 VAL VAL B . n B 2 403 HIS 403 403 403 HIS HIS B . n B 2 404 GLU 404 404 404 GLU GLU B . n B 2 405 ASN 405 405 405 ASN ASN B . n B 2 406 GLU 406 406 406 GLU GLU B . n B 2 407 GLU 407 407 407 GLU GLU B . n B 2 408 GLU 408 408 408 GLU GLU B . n B 2 409 LEU 409 409 409 LEU LEU B . n B 2 410 GLN 410 410 410 GLN GLN B . n B 2 411 SER 411 411 411 SER SER B . n B 2 412 LEU 412 412 412 LEU LEU B . n B 2 413 LYS 413 413 413 LYS LYS B . n B 2 414 LYS 414 414 414 LYS LYS B . n B 2 415 ASP 415 415 415 ASP ASP B . n B 2 416 LEU 416 416 416 LEU LEU B . n B 2 417 LYS 417 417 417 LYS LYS B . n B 2 418 SER 418 418 418 SER SER B . n B 2 419 PHE 419 419 419 PHE PHE B . n B 2 420 ARG 420 420 420 ARG ARG B . n B 2 421 LEU 421 421 421 LEU LEU B . n B 2 422 GLY 422 422 422 GLY GLY B . n B 2 423 MET 423 423 423 MET MET B . n B 2 424 SER 424 424 424 SER SER B . n B 2 425 GLU 425 425 425 GLU GLU B . n B 2 426 ILE 426 426 426 ILE ILE B . n B 2 427 SER 427 427 427 SER SER B . n B 2 428 ASN 428 428 428 ASN ASN B . n B 2 429 ASN 429 429 429 ASN ASN B . n B 2 430 TYR 430 430 430 TYR TYR B . n B 2 431 LEU 431 431 431 LEU LEU B . n B 2 432 CYS 432 432 432 CYS CYS B . n B 2 433 VAL 433 433 433 VAL VAL B . n B 2 434 GLU 434 434 434 GLU GLU B . n B 2 435 SER 435 435 435 SER SER B . n B 2 436 PRO 436 436 436 PRO PRO B . n B 2 437 ILE 437 437 437 ILE ILE B . n B 2 438 GLN 438 438 438 GLN GLN B . n B 2 439 ILE 439 439 439 ILE ILE B . n B 2 440 ALA 440 440 440 ALA ALA B . n B 2 441 ARG 441 441 441 ARG ARG B . n B 2 442 TRP 442 442 442 TRP TRP B . n B 2 443 VAL 443 443 443 VAL VAL B . n B 2 444 PRO 444 444 444 PRO PRO B . n B 2 445 TRP 445 445 445 TRP TRP B . n B 2 446 ASP 446 446 446 ASP ASP B . n B 2 447 HIS 447 447 447 HIS HIS B . n B 2 448 ILE 448 448 448 ILE ILE B . n B 2 449 LEU 449 449 449 LEU LEU B . n B 2 450 LYS 450 450 450 LYS LYS B . n B 2 451 ALA 451 451 451 ALA ALA B . n B 2 452 THR 452 452 452 THR THR B . n B 2 453 ASN 453 453 453 ASN ASN B . n B 2 454 PRO 454 454 454 PRO PRO B . n B 2 455 ASN 455 455 455 ASN ASN B . n B 2 456 GLY 456 456 456 GLY GLY B . n B 2 457 ASN 457 457 457 ASN ASN B . n B 2 458 LEU 458 458 458 LEU LEU B . n B 2 459 SER 459 459 459 SER SER B . n B 2 460 TYR 460 460 460 TYR TYR B . n B 2 461 ASP 461 461 461 ASP ASP B . n B 2 462 ALA 462 462 462 ALA ALA B . n B 2 463 THR 463 463 463 THR THR B . n B 2 464 SER 464 464 464 SER SER B . n B 2 465 THR 465 465 465 THR THR B . n B 2 466 LEU 466 466 466 LEU LEU B . n B 2 467 THR 467 467 467 THR THR B . n B 2 468 LEU 468 468 468 LEU LEU B . n B 2 469 PRO 469 469 469 PRO PRO B . n B 2 470 GLY 470 470 470 GLY GLY B . n B 2 471 HIS 471 471 471 HIS HIS B . n B 2 472 GLU 472 472 472 GLU GLU B . n B 2 473 LEU 473 473 473 LEU LEU B . n B 2 474 PRO 474 474 474 PRO PRO B . n B 2 475 LEU 475 475 475 LEU LEU B . n B 2 476 PRO 476 476 476 PRO PRO B . n B 2 477 LYS 477 477 477 LYS LYS B . n B 2 478 LEU 478 478 478 LEU LEU B . n B 2 479 GLY 479 479 479 GLY GLY B . n B 2 480 VAL 480 480 480 VAL VAL B . n B 2 481 SER 481 481 481 SER SER B . n B 2 482 ALA 482 482 482 ALA ALA B . n B 2 483 ILE 483 483 483 ILE ILE B . n B 2 484 LYS 484 484 484 LYS LYS B . n B 2 485 LEU 485 485 485 LEU LEU B . n B 2 486 LYS 486 486 486 LYS LYS B . n B 2 487 SER 487 487 487 SER SER B . n B 2 488 LEU 488 488 488 LEU LEU B . n B 2 489 MET 489 489 489 MET MET B . n B 2 490 ASN 490 490 490 ASN ASN B . n B 2 491 SER 491 491 491 SER SER B . n B 2 492 THR 492 492 492 THR THR B . n B 2 493 LYS 493 493 493 LYS LYS B . n B 2 494 GLU 494 494 494 GLU GLU B . n B 2 495 SER 495 495 495 SER SER B . n B 2 496 ILE 496 496 496 ILE ILE B . n B 2 497 SER 497 497 497 SER SER B . n B 2 498 LEU 498 498 498 LEU LEU B . n B 2 499 PRO 499 499 499 PRO PRO B . n B 2 500 VAL 500 500 500 VAL VAL B . n B 2 501 ALA 501 501 501 ALA ALA B . n B 2 502 ARG 502 502 502 ARG ARG B . n B 2 503 GLU 503 503 503 GLU GLU B . n B 2 504 CYS 504 504 504 CYS CYS B . n B 2 505 ASN 505 505 505 ASN ASN B . n B 2 506 THR 506 506 506 THR THR B . n B 2 507 ILE 507 507 507 ILE ILE B . n B 2 508 VAL 508 508 508 VAL VAL B . n B 2 509 LEU 509 509 509 LEU LEU B . n B 2 510 CYS 510 510 510 CYS CYS B . n B 2 511 ASP 511 511 511 ASP ASP B . n B 2 512 SER 512 512 512 SER SER B . n B 2 513 SER 513 513 513 SER SER B . n B 2 514 VAL 514 514 514 VAL VAL B . n B 2 515 SER 515 515 515 SER SER B . n B 2 516 THR 516 516 516 THR THR B . n B 2 517 THR 517 517 517 THR THR B . n B 2 518 ASP 518 518 518 ASP ASP B . n B 2 519 ARG 519 519 519 ARG ARG B . n B 2 520 PRO 520 520 520 PRO PRO B . n B 2 521 GLU 521 521 521 GLU GLU B . n B 2 522 LEU 522 522 522 LEU LEU B . n B 2 523 LEU 523 523 523 LEU LEU B . n B 2 524 ARG 524 524 524 ARG ARG B . n B 2 525 LEU 525 525 525 LEU LEU B . n B 2 526 THR 526 526 526 THR THR B . n B 2 527 GLY 527 527 527 GLY GLY B . n B 2 528 GLY 528 528 528 GLY GLY B . n B 2 529 SER 529 529 529 SER SER B . n B 2 530 LYS 530 530 530 LYS LYS B . n B 2 531 THR 531 531 531 THR THR B . n B 2 532 CYS 532 532 532 CYS CYS B . n B 2 533 GLN 533 533 533 GLN GLN B . n B 2 534 PRO 534 534 534 PRO PRO B . n B 2 535 SER 535 535 535 SER SER B . n B 2 536 TRP 536 536 536 TRP TRP B . n B 2 537 ILE 537 537 537 ILE ILE B . n B 2 538 HIS 538 538 538 HIS HIS B . n B 2 539 SER 539 539 539 SER SER B . n B 2 540 GLN 540 540 540 GLN GLN B . n B 2 541 HIS 541 541 541 HIS HIS B . n B 2 542 GLU 542 542 542 GLU GLU B . n B 2 543 LEU 543 543 543 LEU LEU B . n B 2 544 ASN 544 544 544 ASN ASN B . n B 2 545 PRO 545 545 545 PRO PRO B . n B 2 546 GLN 546 546 546 GLN GLN B . n B 2 547 ASP 547 547 547 ASP ASP B . n B 2 548 SER 548 548 548 SER SER B . n B 2 549 ILE 549 549 549 ILE ILE B . n B 2 550 VAL 550 550 550 VAL VAL B . n B 2 551 GLN 551 551 551 GLN GLN B . n B 2 552 GLY 552 552 552 GLY GLY B . n B 2 553 ILE 553 553 553 ILE ILE B . n B 2 554 PHE 554 554 554 PHE PHE B . n B 2 555 GLN 555 555 555 GLN GLN B . n B 2 556 LEU 556 556 556 LEU LEU B . n B 2 557 ALA 557 557 557 ALA ALA B . n B 2 558 THR 558 558 558 THR THR B . n B 2 559 LEU 559 559 559 LEU LEU B . n B 2 560 ALA 560 560 560 ALA ALA B . n B 2 561 LYS 561 561 561 LYS LYS B . n B 2 562 ASP 562 562 562 ASP ASP B . n B 2 563 LYS 563 563 563 LYS LYS B . n B 2 564 ARG 564 564 564 ARG ARG B . n B 2 565 PHE 565 565 565 PHE PHE B . n B 2 566 GLY 566 566 566 GLY GLY B . n B 2 567 LEU 567 567 567 LEU LEU B . n B 2 568 LEU 568 568 568 LEU LEU B . n B 2 569 LEU 569 569 569 LEU LEU B . n B 2 570 LYS 570 570 570 LYS LYS B . n B 2 571 GLU 571 571 571 GLU GLU B . n B 2 572 THR 572 572 572 THR THR B . n B 2 573 GLN 573 573 573 GLN GLN B . n B 2 574 PRO 574 574 574 PRO PRO B . n B 2 575 MET 575 575 575 MET MET B . n B 2 576 LYS 576 576 576 LYS LYS B . n B 2 577 GLN 577 577 577 GLN GLN B . n B 2 578 LYS 578 578 578 LYS LYS B . n B 2 579 SER 579 579 579 SER SER B . n B 2 580 VAL 580 580 580 VAL VAL B . n B 2 581 GLU 581 581 581 GLU GLU B . n B 2 582 THR 582 582 582 THR THR B . n B 2 583 SER 583 583 583 SER SER B . n B 2 584 ASN 584 584 584 ASN ASN B . n B 2 585 GLY 585 585 585 GLY GLY B . n B 2 586 GLY 586 586 586 GLY GLY B . n B 2 587 VAL 587 587 587 VAL VAL B . n B 2 588 GLU 588 588 588 GLU GLU B . n B 2 589 GLU 589 589 589 GLU GLU B . n B 2 590 THR 590 590 590 THR THR B . n B 2 591 MET 591 591 591 MET MET B . n B 2 592 LYS 592 592 592 LYS LYS B . n B 2 593 MET 593 593 593 MET MET B . n loop_ _chem_comp.id _chem_comp.type _chem_comp.mon_nstd_flag _chem_comp.name _chem_comp.pdbx_synonyms _chem_comp.formula _chem_comp.formula_weight ALA "L-peptide linking" y ALANINE ? "C3 H7 N O2" 89.093 ARG "L-peptide linking" y ARGININE ? "C6 H15 N4 O2 1" 175.209 ASN "L-peptide linking" y ASPARAGINE ? "C4 H8 N2 O3" 132.118 ASP "L-peptide linking" y "ASPARTIC ACID" ? "C4 H7 N O4" 133.103 CYS "L-peptide linking" y CYSTEINE ? "C3 H7 N O2 S" 121.158 GLN "L-peptide linking" y GLUTAMINE ? "C5 H10 N2 O3" 146.144 GLU "L-peptide linking" y "GLUTAMIC ACID" ? "C5 H9 N O4" 147.129 GLY "peptide linking" y GLYCINE ? "C2 H5 N O2" 75.067 HIS "L-peptide linking" y HISTIDINE ? "C6 H10 N3 O2 1" 156.162 ILE "L-peptide linking" y ISOLEUCINE ? "C6 H13 N O2" 131.173 LEU "L-peptide linking" y LEUCINE ? "C6 H13 N O2" 131.173 LYS "L-peptide linking" y LYSINE ? "C6 H15 N2 O2 1" 147.195 MET "L-peptide linking" y METHIONINE ? "C5 H11 N O2 S" 149.211 PHE "L-peptide linking" y PHENYLALANINE ? "C9 H11 N O2" 165.189 PRO "L-peptide linking" y PROLINE ? "C5 H9 N O2" 115.130 SER "L-peptide linking" y SERINE ? "C3 H7 N O3" 105.093 THR "L-peptide linking" y THREONINE ? "C4 H9 N O3" 119.119 TRP "L-peptide linking" y TRYPTOPHAN ? "C11 H12 N2 O2" 204.225 TYR "L-peptide linking" y TYROSINE ? "C9 H11 N O3" 181.189 VAL "L-peptide linking" y VALINE ? "C5 H11 N O2" 117.146 loop_ _struct_asym.id _struct_asym.pdbx_PDB_id _struct_asym.pdbx_alt_id _struct_asym.pdbx_blank_PDB_chainid_flag _struct_asym.pdbx_type _struct_asym.pdbx_order _struct_asym.pdbx_modified _struct_asym.entity_id _struct_asym.details A A A N ATOMP 1 N 1 ? B B B N ATOMP 2 N 2 ? _struct_mon_prot_cis.pdbx_id 1 _struct_mon_prot_cis.label_comp_id PHE _struct_mon_prot_cis.label_seq_id 399 _struct_mon_prot_cis.label_asym_id B _struct_mon_prot_cis.label_alt_id . _struct_mon_prot_cis.pdbx_PDB_ins_code ? _struct_mon_prot_cis.auth_comp_id PHE _struct_mon_prot_cis.auth_seq_id 399 _struct_mon_prot_cis.auth_asym_id B _struct_mon_prot_cis.pdbx_label_comp_id_2 PRO _struct_mon_prot_cis.pdbx_label_seq_id_2 400 _struct_mon_prot_cis.pdbx_label_asym_id_2 B _struct_mon_prot_cis.pdbx_PDB_ins_code_2 ? _struct_mon_prot_cis.pdbx_auth_comp_id_2 PRO _struct_mon_prot_cis.pdbx_auth_seq_id_2 400 _struct_mon_prot_cis.pdbx_auth_asym_id_2 B _struct_mon_prot_cis.pdbx_PDB_model_num 1 _struct_mon_prot_cis.pdbx_omega_angle 17.77 _atom_sites.entry_id ma-bak-cepc-0634 _atom_sites.fract_transf_matrix[1][1] 1.000000 _atom_sites.fract_transf_matrix[1][2] 0.000000 _atom_sites.fract_transf_matrix[1][3] 0.000000 _atom_sites.fract_transf_matrix[2][1] 0.000000 _atom_sites.fract_transf_matrix[2][2] 1.000000 _atom_sites.fract_transf_matrix[2][3] 0.000000 _atom_sites.fract_transf_matrix[3][1] 0.000000 _atom_sites.fract_transf_matrix[3][2] 0.000000 _atom_sites.fract_transf_matrix[3][3] 1.000000 _atom_sites.fract_transf_vector[1] 0.00000 _atom_sites.fract_transf_vector[2] 0.00000 _atom_sites.fract_transf_vector[3] 0.00000 loop_ _pdbx_validate_close_contact.id _pdbx_validate_close_contact.PDB_model_num _pdbx_validate_close_contact.auth_atom_id_1 _pdbx_validate_close_contact.auth_asym_id_1 _pdbx_validate_close_contact.auth_comp_id_1 _pdbx_validate_close_contact.auth_seq_id_1 _pdbx_validate_close_contact.PDB_ins_code_1 _pdbx_validate_close_contact.label_alt_id_1 _pdbx_validate_close_contact.auth_atom_id_2 _pdbx_validate_close_contact.auth_asym_id_2 _pdbx_validate_close_contact.auth_comp_id_2 _pdbx_validate_close_contact.auth_seq_id_2 _pdbx_validate_close_contact.PDB_ins_code_2 _pdbx_validate_close_contact.label_alt_id_2 _pdbx_validate_close_contact.dist 1 1 NH2 B ARG 245 ? ? OE1 B GLU 256 ? ? 0.63 2 1 NZ B LYS 349 ? ? O B ASN 490 ? ? 1.41 3 1 NH2 B ARG 246 ? ? NH2 B ARG 248 ? ? 1.42 4 1 CZ B ARG 245 ? ? OE1 B GLU 256 ? ? 1.50 5 1 NH1 B ARG 362 ? ? O B ASP 363 ? ? 1.66 6 1 O B SER 295 ? ? N B THR 296 ? ? 1.75 7 1 O B ALA 2 ? ? N B LEU 3 ? ? 1.76 8 1 SG B CYS 105 ? ? CE B LYS 391 ? ? 1.77 9 1 O B VAL 290 ? ? N B ASP 291 ? ? 1.80 10 1 NH2 B ARG 245 ? ? CD B GLU 256 ? ? 1.87 11 1 CG2 B THR 30 ? ? OH B TYR 80 ? ? 1.92 12 1 ND2 B ASN 505 ? ? NH2 B ARG 524 ? ? 1.94 13 1 O B PHE 250 ? ? CD B GLN 254 ? ? 1.98 14 1 NH2 B ARG 246 ? ? CZ B ARG 248 ? ? 1.98 15 1 O B PHE 250 ? ? OE1 B GLN 254 ? ? 2.01 16 1 OG B SER 347 ? ? OE2 B GLU 352 ? ? 2.05 17 1 NH2 B ARG 243 ? ? OE2 B GLU 256 ? ? 2.06 18 1 NH1 B ARG 243 ? ? OE2 B GLU 256 ? ? 2.08 19 1 O B PHE 298 ? ? N B ASN 300 ? ? 2.08 20 1 CG2 B THR 30 ? ? CZ B TYR 80 ? ? 2.10 21 1 OD1 B ASP 461 ? ? OG1 B THR 463 ? ? 2.14 22 1 CD B LYS 17 ? ? NH1 B ARG 249 ? ? 2.15 23 1 NH2 B ARG 246 ? ? NE B ARG 248 ? ? 2.16 loop_ _pdbx_validate_rmsd_bond.id _pdbx_validate_rmsd_bond.PDB_model_num _pdbx_validate_rmsd_bond.auth_atom_id_1 _pdbx_validate_rmsd_bond.auth_asym_id_1 _pdbx_validate_rmsd_bond.auth_comp_id_1 _pdbx_validate_rmsd_bond.auth_seq_id_1 _pdbx_validate_rmsd_bond.PDB_ins_code_1 _pdbx_validate_rmsd_bond.label_alt_id_1 _pdbx_validate_rmsd_bond.auth_atom_id_2 _pdbx_validate_rmsd_bond.auth_asym_id_2 _pdbx_validate_rmsd_bond.auth_comp_id_2 _pdbx_validate_rmsd_bond.auth_seq_id_2 _pdbx_validate_rmsd_bond.PDB_ins_code_2 _pdbx_validate_rmsd_bond.label_alt_id_2 _pdbx_validate_rmsd_bond.bond_value _pdbx_validate_rmsd_bond.bond_target_value _pdbx_validate_rmsd_bond.bond_deviation _pdbx_validate_rmsd_bond.bond_standard_deviation _pdbx_validate_rmsd_bond.linker_flag 1 1 C A MET 1 ? ? N A PRO 2 ? ? 1.218 1.338 -0.120 0.019 Y 2 1 CD A PRO 10 ? ? N A PRO 10 ? ? 1.332 1.474 -0.142 0.014 N 3 1 CD A PRO 38 ? ? N A PRO 38 ? ? 1.364 1.474 -0.110 0.014 N 4 1 CD A PRO 175 ? ? N A PRO 175 ? ? 1.385 1.474 -0.089 0.014 N 5 1 C B GLN 254 ? ? N B ASN 255 ? ? 1.536 1.336 0.200 0.023 Y 6 1 C B GLU 263 ? ? N B TYR 264 ? ? 1.189 1.336 -0.147 0.023 Y 7 1 C B GLY 386 ? ? N B VAL 387 ? ? 1.190 1.336 -0.146 0.023 Y 8 1 C B PHE 399 ? ? N B PRO 400 ? ? 1.482 1.338 0.144 0.019 Y 9 1 CD B PRO 436 ? ? N B PRO 436 ? ? 1.573 1.474 0.099 0.014 N loop_ _pdbx_validate_rmsd_angle.id _pdbx_validate_rmsd_angle.PDB_model_num _pdbx_validate_rmsd_angle.auth_atom_id_1 _pdbx_validate_rmsd_angle.auth_asym_id_1 _pdbx_validate_rmsd_angle.auth_comp_id_1 _pdbx_validate_rmsd_angle.auth_seq_id_1 _pdbx_validate_rmsd_angle.PDB_ins_code_1 _pdbx_validate_rmsd_angle.label_alt_id_1 _pdbx_validate_rmsd_angle.auth_atom_id_2 _pdbx_validate_rmsd_angle.auth_asym_id_2 _pdbx_validate_rmsd_angle.auth_comp_id_2 _pdbx_validate_rmsd_angle.auth_seq_id_2 _pdbx_validate_rmsd_angle.PDB_ins_code_2 _pdbx_validate_rmsd_angle.label_alt_id_2 _pdbx_validate_rmsd_angle.auth_atom_id_3 _pdbx_validate_rmsd_angle.auth_asym_id_3 _pdbx_validate_rmsd_angle.auth_comp_id_3 _pdbx_validate_rmsd_angle.auth_seq_id_3 _pdbx_validate_rmsd_angle.PDB_ins_code_3 _pdbx_validate_rmsd_angle.label_alt_id_3 _pdbx_validate_rmsd_angle.angle_value _pdbx_validate_rmsd_angle.angle_target_value _pdbx_validate_rmsd_angle.angle_deviation _pdbx_validate_rmsd_angle.angle_standard_deviation _pdbx_validate_rmsd_angle.linker_flag 1 1 O A PRO 2 ? ? C A PRO 2 ? ? N A SER 3 ? ? 108.60 122.70 -14.10 1.60 Y 2 1 C A PRO 2 ? ? N A SER 3 ? ? CA A SER 3 ? ? 151.04 121.70 29.34 2.50 Y 3 1 C A SER 3 ? ? N A LYS 4 ? ? CA A LYS 4 ? ? 137.46 121.70 15.76 2.50 Y 4 1 O A SER 6 ? ? C A SER 6 ? ? N A ILE 7 ? ? 101.10 122.70 -21.60 1.60 Y 5 1 C A SER 6 ? ? N A ILE 7 ? ? CA A ILE 7 ? ? 147.97 121.70 26.27 2.50 Y 6 1 O A ILE 7 ? ? C A ILE 7 ? ? N A ASN 8 ? ? 105.54 122.70 -17.16 1.60 Y 7 1 C A ARG 9 ? ? N A PRO 10 ? ? CA A PRO 10 ? ? 130.78 119.30 11.48 1.50 Y 8 1 C A ARG 9 ? ? N A PRO 10 ? ? CD A PRO 10 ? ? 108.92 128.40 -19.48 2.10 Y 9 1 O A GLY 34 ? ? C A GLY 34 ? ? N A LEU 35 ? ? 108.24 122.70 -14.46 1.60 Y 10 1 C A GLY 34 ? ? N A LEU 35 ? ? CA A LEU 35 ? ? 143.45 121.70 21.75 2.50 Y 11 1 O A SER 47 ? ? C A SER 47 ? ? N A GLY 48 ? ? 103.36 123.20 -19.84 1.70 Y 12 1 O A ILE 50 ? ? C A ILE 50 ? ? N A LYS 51 ? ? 107.94 122.70 -14.76 1.60 Y 13 1 O A LYS 51 ? ? C A LYS 51 ? ? N A SER 52 ? ? 111.39 122.70 -11.31 1.60 Y 14 1 O A GLN 60 ? ? C A GLN 60 ? ? N A ASN 61 ? ? 105.95 122.70 -16.75 1.60 Y 15 1 O A LYS 63 ? ? C A LYS 63 ? ? N A ASN 64 ? ? 104.88 122.70 -17.82 1.60 Y 16 1 O A ASN 64 ? ? C A ASN 64 ? ? N A GLU 65 ? ? 99.58 122.70 -23.12 1.60 Y 17 1 O A GLU 65 ? ? C A GLU 65 ? ? N A SER 66 ? ? 100.02 122.70 -22.68 1.60 Y 18 1 O A SER 66 ? ? C A SER 66 ? ? N A GLN 67 ? ? 105.22 122.70 -17.48 1.60 Y 19 1 O A GLN 67 ? ? C A GLN 67 ? ? N A ASN 68 ? ? 101.27 122.70 -21.43 1.60 Y 20 1 O A ASN 68 ? ? C A ASN 68 ? ? N A SER 69 ? ? 106.39 122.70 -16.31 1.60 Y 21 1 O A SER 69 ? ? C A SER 69 ? ? N A THR 70 ? ? 96.49 122.70 -26.21 1.60 Y 22 1 C A SER 69 ? ? N A THR 70 ? ? CA A THR 70 ? ? 142.60 121.70 20.90 2.50 Y 23 1 O A THR 70 ? ? C A THR 70 ? ? N A ALA 71 ? ? 112.58 122.70 -10.12 1.60 Y 24 1 O A VAL 72 ? ? C A VAL 72 ? ? N A THR 73 ? ? 107.69 122.70 -15.01 1.60 Y 25 1 C A VAL 72 ? ? N A THR 73 ? ? CA A THR 73 ? ? 141.34 121.70 19.64 2.50 Y 26 1 O A LEU 74 ? ? C A LEU 74 ? ? N A GLN 75 ? ? 107.25 122.70 -15.45 1.60 Y 27 1 C A LEU 74 ? ? N A GLN 75 ? ? CA A GLN 75 ? ? 146.17 121.70 24.47 2.50 Y 28 1 C A GLN 75 ? ? N A ASN 76 ? ? CA A ASN 76 ? ? 139.55 121.70 17.85 2.50 Y 29 1 O A ALA 77 ? ? C A ALA 77 ? ? N A SER 78 ? ? 107.79 122.70 -14.91 1.60 Y 30 1 O A SER 78 ? ? C A SER 78 ? ? N A SER 79 ? ? 104.00 122.70 -18.70 1.60 Y 31 1 O A SER 79 ? ? C A SER 79 ? ? N A SER 80 ? ? 96.58 122.70 -26.12 1.60 Y 32 1 C A SER 80 ? ? N A PRO 81 ? ? CA A PRO 81 ? ? 131.50 119.30 12.20 1.50 Y 33 1 C A SER 80 ? ? N A PRO 81 ? ? CD A PRO 81 ? ? 112.05 128.40 -16.35 2.10 Y 34 1 O A PRO 81 ? ? C A PRO 81 ? ? N A ALA 82 ? ? 96.98 122.70 -25.72 1.60 Y 35 1 O A ALA 82 ? ? C A ALA 82 ? ? N A SER 83 ? ? 100.32 122.70 -22.38 1.60 Y 36 1 C A ALA 82 ? ? N A SER 83 ? ? CA A SER 83 ? ? 137.02 121.70 15.32 2.50 Y 37 1 O A SER 83 ? ? C A SER 83 ? ? N A ILE 84 ? ? 97.98 122.70 -24.72 1.60 Y 38 1 O A ILE 84 ? ? C A ILE 84 ? ? N A THR 85 ? ? 111.36 122.70 -11.34 1.60 Y 39 1 C A ILE 84 ? ? N A THR 85 ? ? CA A THR 85 ? ? 141.68 121.70 19.98 2.50 Y 40 1 O A THR 85 ? ? C A THR 85 ? ? N A THR 86 ? ? 112.05 122.70 -10.65 1.60 Y 41 1 C A THR 85 ? ? N A THR 86 ? ? CA A THR 86 ? ? 140.99 121.70 19.29 2.50 Y 42 1 O A ARG 87 ? ? C A ARG 87 ? ? N A THR 88 ? ? 108.43 122.70 -14.27 1.60 Y 43 1 O A GLU 120 ? ? C A GLU 120 ? ? N A MET 121 ? ? 112.55 122.70 -10.15 1.60 Y 44 1 O A MET 121 ? ? C A MET 121 ? ? N A ASP 122 ? ? 104.10 122.70 -18.60 1.60 Y 45 1 C A ILE 123 ? ? N A ASP 124 ? ? CA A ASP 124 ? ? 143.09 121.70 21.39 2.50 Y 46 1 O A GLY 127 ? ? C A GLY 127 ? ? N A GLY 128 ? ? 109.31 123.20 -13.89 1.70 Y 47 1 C A GLY 127 ? ? N A GLY 128 ? ? CA A GLY 128 ? ? 135.90 122.30 13.60 2.10 Y 48 1 O A GLY 128 ? ? C A GLY 128 ? ? N A LYS 129 ? ? 107.82 122.70 -14.88 1.60 Y 49 1 O A LYS 129 ? ? C A LYS 129 ? ? N A LYS 130 ? ? 99.60 122.70 -23.10 1.60 Y 50 1 O A LYS 130 ? ? C A LYS 130 ? ? N A VAL 131 ? ? 100.10 122.70 -22.60 1.60 Y 51 1 O A VAL 131 ? ? C A VAL 131 ? ? N A LYS 132 ? ? 95.89 122.70 -26.81 1.60 Y 52 1 O A LYS 132 ? ? C A LYS 132 ? ? N A GLU 133 ? ? 94.29 122.70 -28.41 1.60 Y 53 1 O A GLU 133 ? ? C A GLU 133 ? ? N A ASN 134 ? ? 97.40 122.70 -25.30 1.60 Y 54 1 O A ASN 134 ? ? C A ASN 134 ? ? N A GLU 135 ? ? 99.76 122.70 -22.94 1.60 Y 55 1 O A GLU 135 ? ? C A GLU 135 ? ? N A LYS 136 ? ? 98.21 122.70 -24.49 1.60 Y 56 1 O A LYS 136 ? ? C A LYS 136 ? ? N A LYS 137 ? ? 103.79 122.70 -18.91 1.60 Y 57 1 O A GLN 157 ? ? C A GLN 157 ? ? N A GLY 158 ? ? 111.93 123.20 -11.27 1.70 Y 58 1 O A GLY 158 ? ? C A GLY 158 ? ? N A LEU 159 ? ? 105.95 122.70 -16.75 1.60 Y 59 1 O A LEU 159 ? ? C A LEU 159 ? ? N A ILE 160 ? ? 110.11 122.70 -12.59 1.60 Y 60 1 O A ASN 163 ? ? C A ASN 163 ? ? N A GLY 164 ? ? 110.91 123.20 -12.29 1.70 Y 61 1 O B MET 1 ? ? C B MET 1 ? ? N B ALA 2 ? ? 112.06 122.70 -10.64 1.60 Y 62 1 C B MET 1 ? ? N B ALA 2 ? ? CA B ALA 2 ? ? 148.65 121.70 26.95 2.50 Y 63 1 O B ALA 2 ? ? C B ALA 2 ? ? N B LEU 3 ? ? 84.58 122.70 -38.12 1.60 Y 64 1 O B LEU 3 ? ? C B LEU 3 ? ? N B ALA 4 ? ? 100.35 122.70 -22.35 1.60 Y 65 1 O B ALA 4 ? ? C B ALA 4 ? ? N B ILE 5 ? ? 98.55 122.70 -24.15 1.60 Y 66 1 O B ILE 5 ? ? C B ILE 5 ? ? N B SER 6 ? ? 112.22 122.70 -10.48 1.60 Y 67 1 O B THR 173 ? ? C B THR 173 ? ? N B GLY 174 ? ? 110.07 123.20 -13.13 1.70 Y 68 1 O B GLY 212 ? ? C B GLY 212 ? ? N B GLY 213 ? ? 108.72 123.20 -14.48 1.70 Y 69 1 O B ALA 252 ? ? C B ALA 252 ? ? N B GLY 253 ? ? 101.16 123.20 -22.04 1.70 Y 70 1 O B ARG 262 ? ? C B ARG 262 ? ? N B GLU 263 ? ? 110.22 122.70 -12.48 1.60 Y 71 1 O B ALA 284 ? ? C B ALA 284 ? ? N B LYS 285 ? ? 105.31 122.70 -17.39 1.60 Y 72 1 O B VAL 290 ? ? C B VAL 290 ? ? N B ASP 291 ? ? 85.36 122.70 -37.34 1.60 Y 73 1 O B ASP 291 ? ? C B ASP 291 ? ? N B ARG 292 ? ? 94.75 122.70 -27.95 1.60 Y 74 1 O B ARG 292 ? ? C B ARG 292 ? ? N B GLY 293 ? ? 96.77 123.20 -26.43 1.70 Y 75 1 O B GLY 293 ? ? C B GLY 293 ? ? N B GLN 294 ? ? 92.24 122.70 -30.46 1.60 Y 76 1 O B GLN 294 ? ? C B GLN 294 ? ? N B SER 295 ? ? 95.28 122.70 -27.42 1.60 Y 77 1 O B SER 295 ? ? C B SER 295 ? ? N B THR 296 ? ? 85.90 122.70 -36.80 1.60 Y 78 1 C B THR 296 ? ? N B PRO 297 ? ? CD B PRO 297 ? ? 108.94 128.40 -19.46 2.10 Y 79 1 O B PHE 298 ? ? C B PHE 298 ? ? N B THR 299 ? ? 90.45 122.70 -32.25 1.60 Y 80 1 O B THR 299 ? ? C B THR 299 ? ? N B ASN 300 ? ? 91.73 122.70 -30.97 1.60 Y 81 1 O B ASN 300 ? ? C B ASN 300 ? ? N B VAL 301 ? ? 97.72 122.70 -24.98 1.60 Y 82 1 O B VAL 301 ? ? C B VAL 301 ? ? N B SER 302 ? ? 109.07 122.70 -13.63 1.60 Y 83 1 C B PHE 399 ? ? N B PRO 400 ? ? CD B PRO 400 ? ? 106.51 120.60 -14.09 2.20 Y 84 1 O B SER 459 ? ? C B SER 459 ? ? N B TYR 460 ? ? 110.10 122.70 -12.60 1.60 Y 85 1 O B SER 464 ? ? C B SER 464 ? ? N B THR 465 ? ? 110.88 122.70 -11.82 1.60 Y 86 1 C B SER 464 ? ? N B THR 465 ? ? CA B THR 465 ? ? 139.19 121.70 17.49 2.50 Y 87 1 O B THR 465 ? ? C B THR 465 ? ? N B LEU 466 ? ? 110.01 122.70 -12.69 1.60 Y 88 1 O B GLN 577 ? ? C B GLN 577 ? ? N B LYS 578 ? ? 110.87 122.70 -11.83 1.60 Y 89 1 O B LYS 578 ? ? C B LYS 578 ? ? N B SER 579 ? ? 102.11 122.70 -20.59 1.60 Y 90 1 O B SER 579 ? ? C B SER 579 ? ? N B VAL 580 ? ? 92.49 122.70 -30.21 1.60 Y 91 1 O B VAL 580 ? ? C B VAL 580 ? ? N B GLU 581 ? ? 92.12 122.70 -30.58 1.60 Y 92 1 O B GLU 581 ? ? C B GLU 581 ? ? N B THR 582 ? ? 96.80 122.70 -25.90 1.60 Y 93 1 O B THR 582 ? ? C B THR 582 ? ? N B SER 583 ? ? 94.88 122.70 -27.82 1.60 Y 94 1 O B SER 583 ? ? C B SER 583 ? ? N B ASN 584 ? ? 101.85 122.70 -20.85 1.60 Y 95 1 O B ASN 584 ? ? C B ASN 584 ? ? N B GLY 585 ? ? 98.25 123.20 -24.95 1.70 Y 96 1 O B GLY 585 ? ? C B GLY 585 ? ? N B GLY 586 ? ? 106.79 123.20 -16.41 1.70 Y 97 1 O B THR 590 ? ? C B THR 590 ? ? N B MET 591 ? ? 112.64 122.70 -10.06 1.60 Y 98 1 C B LYS 592 ? ? N B MET 593 ? ? CA B MET 593 ? ? 140.10 121.70 18.40 2.50 Y loop_ _pdbx_validate_torsion.id _pdbx_validate_torsion.PDB_model_num _pdbx_validate_torsion.auth_comp_id _pdbx_validate_torsion.auth_asym_id _pdbx_validate_torsion.auth_seq_id _pdbx_validate_torsion.PDB_ins_code _pdbx_validate_torsion.label_alt_id _pdbx_validate_torsion.phi _pdbx_validate_torsion.psi 1 1 SER A 3 ? ? 13.59 91.78 2 1 LYS A 4 ? ? -42.26 16.49 3 1 ILE A 7 ? ? -38.15 31.93 4 1 ASN A 8 ? ? -144.32 52.25 5 1 PRO A 10 ? ? -41.89 -6.65 6 1 LEU A 35 ? ? -28.97 11.11 7 1 ARG A 40 ? ? -31.40 -19.91 8 1 ILE A 50 ? ? -41.49 83.34 9 1 GLN A 60 ? ? -10.30 87.77 10 1 LYS A 62 ? ? -79.64 35.46 11 1 ASN A 64 ? ? -144.63 56.01 12 1 GLU A 65 ? ? -156.04 54.28 13 1 SER A 66 ? ? -59.95 72.01 14 1 ASN A 68 ? ? 120.67 84.51 15 1 SER A 69 ? ? 176.91 91.15 16 1 THR A 70 ? ? 51.56 104.06 17 1 ALA A 71 ? ? 116.15 105.96 18 1 VAL A 72 ? ? 179.02 85.25 19 1 THR A 73 ? ? -9.35 95.24 20 1 GLN A 75 ? ? 2.47 115.22 21 1 ASN A 76 ? ? 80.41 102.33 22 1 ALA A 77 ? ? -168.69 92.96 23 1 SER A 78 ? ? 15.99 65.95 24 1 SER A 80 ? ? 35.99 118.12 25 1 PRO A 81 ? ? -59.91 75.75 26 1 ALA A 82 ? ? -33.43 86.77 27 1 SER A 83 ? ? 10.80 68.44 28 1 THR A 86 ? ? -67.96 20.97 29 1 THR A 88 ? ? -53.00 107.96 30 1 SER A 90 ? ? -37.76 139.48 31 1 ASP A 122 ? ? -44.21 87.07 32 1 ASP A 124 ? ? 21.76 113.25 33 1 LEU A 125 ? ? 135.78 109.84 34 1 ASP A 126 ? ? 86.83 101.85 35 1 LYS A 129 ? ? -157.98 73.13 36 1 LYS A 130 ? ? 14.86 55.80 37 1 VAL A 131 ? ? -56.36 58.67 38 1 LYS A 132 ? ? -5.64 59.78 39 1 GLU A 133 ? ? 9.90 62.50 40 1 ASN A 134 ? ? -12.27 51.62 41 1 GLU A 135 ? ? -32.14 78.37 42 1 LYS A 136 ? ? -12.77 72.65 43 1 LYS A 137 ? ? -34.11 124.20 44 1 LEU A 159 ? ? -36.64 89.89 45 1 ILE A 160 ? ? -60.70 89.52 46 1 GLN A 165 ? ? -52.61 -5.97 47 1 PRO A 172 ? ? -71.60 49.73 48 1 ALA B 2 ? ? -51.69 66.31 49 1 LEU B 3 ? ? -0.34 77.69 50 1 ALA B 4 ? ? -18.10 41.72 51 1 ILE B 5 ? ? -59.02 103.89 52 1 SER B 6 ? ? -27.36 124.72 53 1 HIS B 7 ? ? -34.56 -37.65 54 1 ASN B 82 ? ? 99.02 -3.74 55 1 ASP B 98 ? ? 56.84 -101.46 56 1 THR B 124 ? ? -57.51 -6.05 57 1 SER B 216 ? ? -63.64 13.91 58 1 PHE B 250 ? ? 90.40 -21.53 59 1 ASN B 255 ? ? 169.16 20.91 60 1 GLU B 256 ? ? -51.24 92.49 61 1 GLU B 263 ? ? 99.32 60.41 62 1 ASP B 283 ? ? -64.67 1.84 63 1 LYS B 285 ? ? -41.78 -15.46 64 1 ASP B 291 ? ? -35.63 71.47 65 1 ARG B 292 ? ? -9.26 70.42 66 1 GLN B 294 ? ? 36.31 55.71 67 1 SER B 295 ? ? -14.68 51.06 68 1 THR B 296 ? ? -15.38 104.47 69 1 PRO B 297 ? ? -41.20 22.42 70 1 THR B 299 ? ? 9.01 40.79 71 1 ASN B 300 ? ? -64.46 76.11 72 1 VAL B 301 ? ? -7.90 69.78 73 1 GLU B 404 ? ? -62.99 63.14 74 1 SER B 464 ? ? -67.42 92.78 75 1 THR B 465 ? ? -68.99 10.99 76 1 LEU B 466 ? ? -158.24 35.96 77 1 ASP B 518 ? ? 56.31 11.05 78 1 TRP B 536 ? ? -69.35 98.61 79 1 GLN B 577 ? ? -62.92 98.94 80 1 LYS B 578 ? ? -46.82 80.79 81 1 SER B 579 ? ? -32.23 69.59 82 1 VAL B 580 ? ? -24.12 57.98 83 1 GLU B 581 ? ? -20.00 66.68 84 1 THR B 582 ? ? -24.23 61.37 85 1 SER B 583 ? ? -28.28 57.20 86 1 VAL B 587 ? ? 110.08 112.81 87 1 GLU B 588 ? ? 106.86 111.73 88 1 GLU B 589 ? ? 74.08 113.49 89 1 THR B 590 ? ? 99.05 105.18 90 1 MET B 591 ? ? -172.60 101.63 91 1 LYS B 592 ? ? 88.97 103.96 loop_ _pdbx_validate_peptide_omega.id _pdbx_validate_peptide_omega.PDB_model_num _pdbx_validate_peptide_omega.auth_comp_id_1 _pdbx_validate_peptide_omega.auth_asym_id_1 _pdbx_validate_peptide_omega.auth_seq_id_1 _pdbx_validate_peptide_omega.PDB_ins_code_1 _pdbx_validate_peptide_omega.label_alt_id_1 _pdbx_validate_peptide_omega.auth_comp_id_2 _pdbx_validate_peptide_omega.auth_asym_id_2 _pdbx_validate_peptide_omega.auth_seq_id_2 _pdbx_validate_peptide_omega.PDB_ins_code_2 _pdbx_validate_peptide_omega.label_alt_id_2 _pdbx_validate_peptide_omega.omega 1 1 GLN A 60 ? ? ASN A 61 ? ? 125.55 2 1 ASN A 64 ? ? GLU A 65 ? ? 149.19 3 1 GLU A 65 ? ? SER A 66 ? ? 147.49 4 1 SER A 66 ? ? GLN A 67 ? ? 140.04 5 1 GLN A 67 ? ? ASN A 68 ? ? 132.13 6 1 ASN A 68 ? ? SER A 69 ? ? 134.55 7 1 SER A 69 ? ? THR A 70 ? ? 121.08 8 1 THR A 70 ? ? ALA A 71 ? ? 115.21 9 1 ALA A 71 ? ? VAL A 72 ? ? 116.48 10 1 VAL A 72 ? ? THR A 73 ? ? 128.98 11 1 THR A 73 ? ? LEU A 74 ? ? 141.66 12 1 LEU A 74 ? ? GLN A 75 ? ? 123.14 13 1 GLN A 75 ? ? ASN A 76 ? ? 106.08 14 1 ASN A 76 ? ? ALA A 77 ? ? 131.64 15 1 ALA A 77 ? ? SER A 78 ? ? 131.09 16 1 SER A 79 ? ? SER A 80 ? ? 143.38 17 1 ALA A 82 ? ? SER A 83 ? ? 148.36 18 1 MET A 121 ? ? ASP A 122 ? ? 149.01 19 1 ILE A 123 ? ? ASP A 124 ? ? 120.06 20 1 ASP A 124 ? ? LEU A 125 ? ? 115.25 21 1 LEU A 125 ? ? ASP A 126 ? ? 107.76 22 1 ASP A 126 ? ? GLY A 127 ? ? 123.80 23 1 GLY A 127 ? ? GLY A 128 ? ? 120.13 24 1 GLY A 128 ? ? LYS A 129 ? ? 148.75 25 1 LYS A 129 ? ? LYS A 130 ? ? 146.82 26 1 LYS A 132 ? ? GLU A 133 ? ? 140.53 27 1 ARG B 292 ? ? GLY B 293 ? ? 136.34 28 1 GLY B 293 ? ? GLN B 294 ? ? 130.14 29 1 THR B 582 ? ? SER B 583 ? ? 145.50 30 1 ASN B 584 ? ? GLY B 585 ? ? 136.39 31 1 GLY B 585 ? ? GLY B 586 ? ? 127.04 32 1 GLY B 586 ? ? VAL B 587 ? ? 114.76 33 1 VAL B 587 ? ? GLU B 588 ? ? 112.37 34 1 GLU B 588 ? ? GLU B 589 ? ? 107.07 35 1 GLU B 589 ? ? THR B 590 ? ? 116.40 36 1 THR B 590 ? ? MET B 591 ? ? 138.29 37 1 MET B 591 ? ? LYS B 592 ? ? 110.41 38 1 LYS B 592 ? ? MET B 593 ? ? 129.93 loop_ _pdbx_validate_main_chain_plane.id _pdbx_validate_main_chain_plane.PDB_model_num _pdbx_validate_main_chain_plane.auth_comp_id _pdbx_validate_main_chain_plane.auth_asym_id _pdbx_validate_main_chain_plane.auth_seq_id _pdbx_validate_main_chain_plane.PDB_ins_code _pdbx_validate_main_chain_plane.label_alt_id _pdbx_validate_main_chain_plane.improper_torsion_angle 1 1 PRO A 2 ? ? 23.54 2 1 SER A 3 ? ? 21.50 3 1 LYS A 4 ? ? -11.20 4 1 SER A 6 ? ? 28.76 5 1 ILE A 7 ? ? -23.70 6 1 ARG A 9 ? ? 12.02 7 1 PRO A 10 ? ? -13.18 8 1 ALA A 33 ? ? -11.98 9 1 GLY A 34 ? ? 19.87 10 1 LEU A 35 ? ? -11.37 11 1 LYS A 37 ? ? 10.63 12 1 PRO A 38 ? ? 14.25 13 1 ALA A 39 ? ? 13.48 14 1 SER A 45 ? ? 12.95 15 1 SER A 47 ? ? 26.40 16 1 GLU A 49 ? ? 17.65 17 1 ILE A 50 ? ? 23.00 18 1 LYS A 51 ? ? 17.40 19 1 SER A 52 ? ? 15.69 20 1 GLN A 60 ? ? 24.06 21 1 LYS A 62 ? ? -10.76 22 1 LYS A 63 ? ? -24.76 23 1 ASN A 64 ? ? 30.24 24 1 GLU A 65 ? ? 30.25 25 1 SER A 66 ? ? 23.79 26 1 GLN A 67 ? ? 27.97 27 1 ASN A 68 ? ? 19.42 28 1 SER A 69 ? ? 28.95 29 1 THR A 70 ? ? 14.56 30 1 ALA A 71 ? ? 10.45 31 1 VAL A 72 ? ? 21.52 32 1 THR A 73 ? ? 13.75 33 1 LEU A 74 ? ? 20.13 34 1 ALA A 77 ? ? 22.30 35 1 SER A 78 ? ? 22.99 36 1 SER A 79 ? ? 31.34 37 1 SER A 80 ? ? 11.00 38 1 PRO A 81 ? ? 32.14 39 1 ALA A 82 ? ? 28.97 40 1 SER A 83 ? ? 30.78 41 1 ILE A 84 ? ? 19.38 42 1 THR A 85 ? ? 15.10 43 1 ARG A 87 ? ? 21.12 44 1 THR A 88 ? ? 17.57 45 1 LEU A 89 ? ? 15.44 46 1 GLU A 120 ? ? -18.16 47 1 MET A 121 ? ? 25.47 48 1 ASP A 122 ? ? 12.98 49 1 ILE A 123 ? ? 14.80 50 1 LEU A 125 ? ? 10.01 51 1 GLY A 127 ? ? 17.38 52 1 GLY A 128 ? ? 20.59 53 1 LYS A 129 ? ? 29.98 54 1 LYS A 130 ? ? 28.52 55 1 VAL A 131 ? ? 32.55 56 1 LYS A 132 ? ? 34.00 57 1 GLU A 133 ? ? 30.72 58 1 ASN A 134 ? ? 28.56 59 1 GLU A 135 ? ? 30.04 60 1 LYS A 136 ? ? 27.29 61 1 LYS A 137 ? ? 10.69 62 1 SER A 138 ? ? 10.72 63 1 GLN A 157 ? ? -18.02 64 1 GLY A 158 ? ? 22.43 65 1 LEU A 159 ? ? 19.12 66 1 ILE A 160 ? ? 14.42 67 1 ILE A 161 ? ? 13.21 68 1 GLU A 162 ? ? 11.49 69 1 ASN A 163 ? ? 16.77 70 1 GLY A 164 ? ? 12.95 71 1 MET B 1 ? ? 16.89 72 1 ALA B 2 ? ? 39.43 73 1 LEU B 3 ? ? 29.60 74 1 ALA B 4 ? ? 30.33 75 1 ILE B 5 ? ? 19.59 76 1 SER B 6 ? ? 13.49 77 1 LYS B 81 ? ? 12.94 78 1 THR B 173 ? ? 21.05 79 1 GLY B 212 ? ? -22.77 80 1 SER B 215 ? ? 15.24 81 1 SER B 216 ? ? -10.23 82 1 ALA B 252 ? ? 26.77 83 1 GLN B 254 ? ? -11.87 84 1 ASN B 255 ? ? 15.13 85 1 GLU B 256 ? ? 19.26 86 1 ARG B 262 ? ? 20.18 87 1 ALA B 284 ? ? 24.15 88 1 VAL B 289 ? ? -12.54 89 1 VAL B 290 ? ? 39.58 90 1 ASP B 291 ? ? 32.03 91 1 ARG B 292 ? ? 32.14 92 1 GLY B 293 ? ? 35.23 93 1 GLN B 294 ? ? 33.37 94 1 SER B 295 ? ? 39.88 95 1 THR B 296 ? ? 19.77 96 1 PHE B 298 ? ? 36.36 97 1 THR B 299 ? ? 34.85 98 1 ASN B 300 ? ? 31.20 99 1 VAL B 301 ? ? 23.24 100 1 THR B 344 ? ? 10.36 101 1 SER B 347 ? ? 10.58 102 1 ALA B 350 ? ? 16.19 103 1 GLN B 385 ? ? 12.85 104 1 GLU B 404 ? ? 12.51 105 1 ALA B 451 ? ? 10.35 106 1 SER B 459 ? ? 23.07 107 1 TYR B 460 ? ? 10.07 108 1 SER B 464 ? ? 17.20 109 1 THR B 465 ? ? -22.31 110 1 GLY B 527 ? ? 10.59 111 1 GLN B 577 ? ? 19.42 112 1 LYS B 578 ? ? 27.34 113 1 SER B 579 ? ? 35.18 114 1 VAL B 580 ? ? 34.76 115 1 GLU B 581 ? ? 31.75 116 1 THR B 582 ? ? 32.95 117 1 SER B 583 ? ? 28.03 118 1 ASN B 584 ? ? 29.13 119 1 GLY B 585 ? ? 23.73 120 1 GLY B 586 ? ? 16.42 121 1 GLU B 589 ? ? 10.08 122 1 THR B 590 ? ? 16.39 123 1 MET B 591 ? ? 16.32 124 1 LYS B 592 ? ? 14.21 loop_ _pdbx_validate_polymer_linkage.id _pdbx_validate_polymer_linkage.PDB_model_num _pdbx_validate_polymer_linkage.auth_atom_id_1 _pdbx_validate_polymer_linkage.auth_asym_id_1 _pdbx_validate_polymer_linkage.auth_comp_id_1 _pdbx_validate_polymer_linkage.auth_seq_id_1 _pdbx_validate_polymer_linkage.PDB_ins_code_1 _pdbx_validate_polymer_linkage.label_alt_id_1 _pdbx_validate_polymer_linkage.auth_atom_id_2 _pdbx_validate_polymer_linkage.auth_asym_id_2 _pdbx_validate_polymer_linkage.auth_comp_id_2 _pdbx_validate_polymer_linkage.auth_seq_id_2 _pdbx_validate_polymer_linkage.PDB_ins_code_2 _pdbx_validate_polymer_linkage.label_alt_id_2 _pdbx_validate_polymer_linkage.dist 1 1 C B GLU 263 ? ? N B TYR 264 ? ? 1.19 2 1 C B GLY 386 ? ? N B VAL 387 ? ? 1.19 loop_ _atom_type.symbol C N O S loop_ _atom_site.group_PDB _atom_site.id _atom_site.type_symbol _atom_site.label_atom_id _atom_site.label_alt_id _atom_site.label_comp_id _atom_site.label_asym_id _atom_site.label_entity_id _atom_site.label_seq_id _atom_site.pdbx_PDB_ins_code _atom_site.Cartn_x _atom_site.Cartn_y _atom_site.Cartn_z _atom_site.occupancy _atom_site.B_iso_or_equiv _atom_site.pdbx_formal_charge _atom_site.auth_seq_id _atom_site.auth_comp_id _atom_site.auth_asym_id _atom_site.auth_atom_id _atom_site.pdbx_auth_seq_id _atom_site.pdbx_auth_comp_id _atom_site.pdbx_auth_asym_id _atom_site.pdbx_auth_atom_name _atom_site.pdbx_PDB_model_num ATOM 1 N N . MET A 1 1 ? -47.030 24.666 -5.959 1.00 41.00 ? 1 MET A N 1 MET A N 1 ATOM 2 C CA . MET A 1 1 ? -47.351 24.861 -7.370 1.00 41.00 ? 1 MET A CA 1 MET A CA 1 ATOM 3 C C . MET A 1 1 ? -46.762 26.169 -7.887 1.00 41.00 ? 1 MET A C 1 MET A C 1 ATOM 4 O O . MET A 1 1 ? -47.209 27.251 -7.502 1.00 41.00 ? 1 MET A O 1 MET A O 1 ATOM 5 C CB . MET A 1 1 ? -48.866 24.849 -7.584 1.00 41.00 ? 1 MET A CB 1 MET A CB 1 ATOM 6 C CG . MET A 1 1 ? -49.465 23.453 -7.648 1.00 41.00 ? 1 MET A CG 1 MET A CG 1 ATOM 7 S SD . MET A 1 1 ? -51.133 23.439 -8.413 1.00 41.00 ? 1 MET A SD 1 MET A SD 1 ATOM 8 C CE . MET A 1 1 ? -51.354 21.656 -8.665 1.00 41.00 ? 1 MET A CE 1 MET A CE 1 ATOM 9 N N . PRO A 1 2 ? -45.677 26.179 -8.440 1.00 44.01 ? 2 PRO A N 2 PRO A N 1 ATOM 10 C CA . PRO A 1 2 ? -45.215 27.324 -9.228 1.00 44.01 ? 2 PRO A CA 2 PRO A CA 1 ATOM 11 C C . PRO A 1 2 ? -45.385 27.113 -10.731 1.00 44.01 ? 2 PRO A C 2 PRO A C 1 ATOM 12 O O . PRO A 1 2 ? -45.190 26.001 -11.228 1.00 44.01 ? 2 PRO A O 2 PRO A O 1 ATOM 13 C CB . PRO A 1 2 ? -43.734 27.433 -8.856 1.00 44.01 ? 2 PRO A CB 2 PRO A CB 1 ATOM 14 C CG . PRO A 1 2 ? -43.386 26.099 -8.278 1.00 44.01 ? 2 PRO A CG 2 PRO A CG 1 ATOM 15 C CD . PRO A 1 2 ? -44.590 25.207 -8.379 1.00 44.01 ? 2 PRO A CD 2 PRO A CD 1 ATOM 16 N N . SER A 1 3 ? -46.476 27.658 -11.310 1.00 45.63 ? 3 SER A N 3 SER A N 1 ATOM 17 C CA . SER A 1 3 ? -47.153 28.238 -12.465 1.00 45.63 ? 3 SER A CA 3 SER A CA 1 ATOM 18 C C . SER A 1 3 ? -46.366 27.995 -13.748 1.00 45.63 ? 3 SER A C 3 SER A C 1 ATOM 19 O O . SER A 1 3 ? -45.151 28.202 -13.785 1.00 45.63 ? 3 SER A O 3 SER A O 1 ATOM 20 C CB . SER A 1 3 ? -47.365 29.740 -12.264 1.00 45.63 ? 3 SER A CB 3 SER A CB 1 ATOM 21 O OG . SER A 1 3 ? -46.317 30.480 -12.865 1.00 45.63 ? 3 SER A OG 3 SER A OG 1 ATOM 22 N N . LYS A 1 4 ? -46.736 26.889 -14.361 1.00 49.18 ? 4 LYS A N 4 LYS A N 1 ATOM 23 C CA . LYS A 1 4 ? -46.465 26.220 -15.631 1.00 49.18 ? 4 LYS A CA 4 LYS A CA 1 ATOM 24 C C . LYS A 1 4 ? -46.444 27.218 -16.785 1.00 49.18 ? 4 LYS A C 4 LYS A C 1 ATOM 25 O O . LYS A 1 4 ? -46.144 26.852 -17.923 1.00 49.18 ? 4 LYS A O 4 LYS A O 1 ATOM 26 C CB . LYS A 1 4 ? -47.507 25.132 -15.897 1.00 49.18 ? 4 LYS A CB 4 LYS A CB 1 ATOM 27 C CG . LYS A 1 4 ? -47.304 23.867 -15.077 1.00 49.18 ? 4 LYS A CG 4 LYS A CG 1 ATOM 28 C CD . LYS A 1 4 ? -48.278 22.771 -15.490 1.00 49.18 ? 4 LYS A CD 4 LYS A CD 1 ATOM 29 C CE . LYS A 1 4 ? -48.075 21.503 -14.672 1.00 49.18 ? 4 LYS A CE 4 LYS A CE 1 ATOM 30 N NZ . LYS A 1 4 ? -49.024 20.423 -15.078 1.00 49.18 ? 4 LYS A NZ 4 LYS A NZ 1 ATOM 31 N N . ASN A 1 5 ? -46.316 28.607 -16.441 1.00 52.15 ? 5 ASN A N 5 ASN A N 1 ATOM 32 C CA . ASN A 1 5 ? -46.266 29.450 -17.631 1.00 52.15 ? 5 ASN A CA 5 ASN A CA 1 ATOM 33 C C . ASN A 1 5 ? -45.040 30.359 -17.623 1.00 52.15 ? 5 ASN A C 5 ASN A C 1 ATOM 34 O O . ASN A 1 5 ? -45.100 31.493 -18.101 1.00 52.15 ? 5 ASN A O 5 ASN A O 1 ATOM 35 C CB . ASN A 1 5 ? -47.544 30.283 -17.754 1.00 52.15 ? 5 ASN A CB 5 ASN A CB 1 ATOM 36 C CG . ASN A 1 5 ? -48.679 29.519 -18.406 1.00 52.15 ? 5 ASN A CG 5 ASN A CG 1 ATOM 37 O OD1 . ASN A 1 5 ? -48.479 28.426 -18.944 1.00 52.15 ? 5 ASN A OD1 5 ASN A OD1 1 ATOM 38 N ND2 . ASN A 1 5 ? -49.878 30.087 -18.364 1.00 52.15 ? 5 ASN A ND2 5 ASN A ND2 1 ATOM 39 N N . SER A 1 6 ? -43.857 29.968 -17.181 1.00 49.42 ? 6 SER A N 6 SER A N 1 ATOM 40 C CA . SER A 1 6 ? -42.716 30.859 -17.362 1.00 49.42 ? 6 SER A CA 6 SER A CA 1 ATOM 41 C C . SER A 1 6 ? -41.969 30.544 -18.654 1.00 49.42 ? 6 SER A C 6 SER A C 1 ATOM 42 O O . SER A 1 6 ? -41.738 29.377 -18.975 1.00 49.42 ? 6 SER A O 6 SER A O 1 ATOM 43 C CB . SER A 1 6 ? -41.761 30.756 -16.172 1.00 49.42 ? 6 SER A CB 6 SER A CB 1 ATOM 44 O OG . SER A 1 6 ? -40.941 29.606 -16.284 1.00 49.42 ? 6 SER A OG 6 SER A OG 1 ATOM 45 N N . ILE A 1 7 ? -42.418 31.044 -19.808 1.00 55.66 ? 7 ILE A N 7 ILE A N 1 ATOM 46 C CA . ILE A 1 7 ? -42.185 31.276 -21.229 1.00 55.66 ? 7 ILE A CA 7 ILE A CA 1 ATOM 47 C C . ILE A 1 7 ? -40.717 31.627 -21.461 1.00 55.66 ? 7 ILE A C 7 ILE A C 1 ATOM 48 O O . ILE A 1 7 ? -40.249 31.644 -22.602 1.00 55.66 ? 7 ILE A O 7 ILE A O 1 ATOM 49 C CB . ILE A 1 7 ? -43.097 32.397 -21.776 1.00 55.66 ? 7 ILE A CB 7 ILE A CB 1 ATOM 50 C CG1 . ILE A 1 7 ? -44.568 31.974 -21.699 1.00 55.66 ? 7 ILE A CG1 7 ILE A CG1 1 ATOM 51 C CG2 . ILE A 1 7 ? -42.705 32.759 -23.212 1.00 55.66 ? 7 ILE A CG2 7 ILE A CG2 1 ATOM 52 C CD1 . ILE A 1 7 ? -45.553 33.121 -21.883 1.00 55.66 ? 7 ILE A CD1 7 ILE A CD1 1 ATOM 53 N N . ASN A 1 8 ? -39.718 31.094 -20.657 1.00 46.94 ? 8 ASN A N 8 ASN A N 1 ATOM 54 C CA . ASN A 1 8 ? -38.376 31.285 -21.196 1.00 46.94 ? 8 ASN A CA 8 ASN A CA 1 ATOM 55 C C . ASN A 1 8 ? -37.475 30.091 -20.895 1.00 46.94 ? 8 ASN A C 8 ASN A C 1 ATOM 56 O O . ASN A 1 8 ? -36.471 30.227 -20.195 1.00 46.94 ? 8 ASN A O 8 ASN A O 1 ATOM 57 C CB . ASN A 1 8 ? -37.755 32.571 -20.647 1.00 46.94 ? 8 ASN A CB 8 ASN A CB 1 ATOM 58 C CG . ASN A 1 8 ? -37.857 33.731 -21.618 1.00 46.94 ? 8 ASN A CG 8 ASN A CG 1 ATOM 59 O OD1 . ASN A 1 8 ? -38.169 33.543 -22.797 1.00 46.94 ? 8 ASN A OD1 8 ASN A OD1 1 ATOM 60 N ND2 . ASN A 1 8 ? -37.596 34.938 -21.130 1.00 46.94 ? 8 ASN A ND2 8 ASN A ND2 1 ATOM 61 N N . ARG A 1 9 ? -37.928 28.825 -21.239 1.00 53.05 ? 9 ARG A N 9 ARG A N 1 ATOM 62 C CA . ARG A 1 9 ? -36.912 27.785 -21.110 1.00 53.05 ? 9 ARG A CA 9 ARG A CA 1 ATOM 63 C C . ARG A 1 9 ? -36.357 27.390 -22.474 1.00 53.05 ? 9 ARG A C 9 ARG A C 1 ATOM 64 O O . ARG A 1 9 ? -37.113 27.016 -23.374 1.00 53.05 ? 9 ARG A O 9 ARG A O 1 ATOM 65 C CB . ARG A 1 9 ? -37.487 26.556 -20.402 1.00 53.05 ? 9 ARG A CB 9 ARG A CB 1 ATOM 66 C CG . ARG A 1 9 ? -37.611 26.715 -18.895 1.00 53.05 ? 9 ARG A CG 9 ARG A CG 1 ATOM 67 C CD . ARG A 1 9 ? -37.893 25.385 -18.210 1.00 53.05 ? 9 ARG A CD 9 ARG A CD 1 ATOM 68 N NE . ARG A 1 9 ? -38.061 25.547 -16.768 1.00 53.05 ? 9 ARG A NE 9 ARG A NE 1 ATOM 69 C CZ . ARG A 1 9 ? -38.189 24.545 -15.903 1.00 53.05 ? 9 ARG A CZ 9 ARG A CZ 1 ATOM 70 N NH1 . ARG A 1 9 ? -38.172 23.284 -16.318 1.00 53.05 ? 9 ARG A NH1 9 ARG A NH1 1 ATOM 71 N NH2 . ARG A 1 9 ? -38.336 24.806 -14.612 1.00 53.05 ? 9 ARG A NH2 9 ARG A NH2 1 ATOM 72 N N . PRO A 1 10 ? -35.171 27.775 -22.955 1.00 56.94 ? 10 PRO A N 10 PRO A N 1 ATOM 73 C CA . PRO A 1 10 ? -34.431 27.336 -24.141 1.00 56.94 ? 10 PRO A CA 10 PRO A CA 1 ATOM 74 C C . PRO A 1 10 ? -34.481 25.824 -24.342 1.00 56.94 ? 10 PRO A C 10 PRO A C 1 ATOM 75 O O . PRO A 1 10 ? -34.458 25.347 -25.480 1.00 56.94 ? 10 PRO A O 10 PRO A O 1 ATOM 76 C CB . PRO A 1 10 ? -33.001 27.802 -23.856 1.00 56.94 ? 10 PRO A CB 10 PRO A CB 1 ATOM 77 C CG . PRO A 1 10 ? -33.020 28.241 -22.427 1.00 56.94 ? 10 PRO A CG 10 PRO A CG 1 ATOM 78 C CD . PRO A 1 10 ? -34.446 28.284 -21.960 1.00 56.94 ? 10 PRO A CD 10 PRO A CD 1 ATOM 79 N N . LYS A 1 11 ? -35.112 25.044 -23.265 1.00 60.74 ? 11 LYS A N 11 LYS A N 1 ATOM 80 C CA . LYS A 1 11 ? -34.975 23.595 -23.381 1.00 60.74 ? 11 LYS A CA 11 LYS A CA 1 ATOM 81 C C . LYS A 1 11 ? -36.219 22.974 -24.010 1.00 60.74 ? 11 LYS A C 11 LYS A C 1 ATOM 82 O O . LYS A 1 11 ? -36.135 21.937 -24.671 1.00 60.74 ? 11 LYS A O 11 LYS A O 1 ATOM 83 C CB . LYS A 1 11 ? -34.712 22.969 -22.011 1.00 60.74 ? 11 LYS A CB 11 LYS A CB 1 ATOM 84 C CG . LYS A 1 11 ? -33.284 23.143 -21.514 1.00 60.74 ? 11 LYS A CG 11 LYS A CG 1 ATOM 85 C CD . LYS A 1 11 ? -33.019 22.304 -20.271 1.00 60.74 ? 11 LYS A CD 11 LYS A CD 1 ATOM 86 C CE . LYS A 1 11 ? -31.596 22.493 -19.762 1.00 60.74 ? 11 LYS A CE 11 LYS A CE 1 ATOM 87 N NZ . LYS A 1 11 ? -31.316 21.634 -18.572 1.00 60.74 ? 11 LYS A NZ 11 LYS A NZ 1 ATOM 88 N N . LEU A 1 12 ? -37.364 23.791 -24.032 1.00 61.71 ? 12 LEU A N 12 LEU A N 1 ATOM 89 C CA . LEU A 1 12 ? -38.582 23.264 -24.637 1.00 61.71 ? 12 LEU A CA 12 LEU A CA 1 ATOM 90 C C . LEU A 1 12 ? -38.508 23.336 -26.159 1.00 61.71 ? 12 LEU A C 12 LEU A C 1 ATOM 91 O O . LEU A 1 12 ? -38.917 22.399 -26.849 1.00 61.71 ? 12 LEU A O 12 LEU A O 1 ATOM 92 C CB . LEU A 1 12 ? -39.806 24.035 -24.137 1.00 61.71 ? 12 LEU A CB 12 LEU A CB 1 ATOM 93 C CG . LEU A 1 12 ? -40.853 23.223 -23.373 1.00 61.71 ? 12 LEU A CG 12 LEU A CG 1 ATOM 94 C CD1 . LEU A 1 12 ? -41.404 24.034 -22.205 1.00 61.71 ? 12 LEU A CD1 12 LEU A CD1 1 ATOM 95 C CD2 . LEU A 1 12 ? -41.979 22.789 -24.306 1.00 61.71 ? 12 LEU A CD2 12 LEU A CD2 1 ATOM 96 N N . THR A 1 13 ? -37.857 24.429 -26.687 1.00 71.02 ? 13 THR A N 13 THR A N 1 ATOM 97 C CA . THR A 1 13 ? -37.718 24.527 -28.136 1.00 71.02 ? 13 THR A CA 13 THR A CA 1 ATOM 98 C C . THR A 1 13 ? -36.789 23.439 -28.665 1.00 71.02 ? 13 THR A C 13 THR A C 1 ATOM 99 O O . THR A 1 13 ? -37.073 22.817 -29.691 1.00 71.02 ? 13 THR A O 13 THR A O 1 ATOM 100 C CB . THR A 1 13 ? -37.184 25.910 -28.553 1.00 71.02 ? 13 THR A CB 13 THR A CB 1 ATOM 101 O OG1 . THR A 1 13 ? -36.092 26.271 -27.698 1.00 71.02 ? 13 THR A OG1 13 THR A OG1 1 ATOM 102 C CG2 . THR A 1 13 ? -38.270 26.975 -28.447 1.00 71.02 ? 13 THR A CG2 13 THR A CG2 1 ATOM 103 N N . SER A 1 14 ? -35.709 23.165 -27.829 1.00 73.22 ? 14 SER A N 14 SER A N 1 ATOM 104 C CA . SER A 1 14 ? -34.769 22.132 -28.252 1.00 73.22 ? 14 SER A CA 14 SER A CA 1 ATOM 105 C C . SER A 1 14 ? -35.396 20.745 -28.163 1.00 73.22 ? 14 SER A C 14 SER A C 1 ATOM 106 O O . SER A 1 14 ? -35.210 19.915 -29.056 1.00 73.22 ? 14 SER A O 14 SER A O 1 ATOM 107 C CB . SER A 1 14 ? -33.499 22.182 -27.402 1.00 73.22 ? 14 SER A CB 14 SER A CB 1 ATOM 108 O OG . SER A 1 14 ? -33.745 21.681 -26.100 1.00 73.22 ? 14 SER A OG 14 SER A OG 1 ATOM 109 N N . ASN A 1 15 ? -36.213 20.562 -27.119 1.00 78.90 ? 15 ASN A N 15 ASN A N 1 ATOM 110 C CA . ASN A 1 15 ? -36.872 19.270 -26.965 1.00 78.90 ? 15 ASN A CA 15 ASN A CA 1 ATOM 111 C C . ASN A 1 15 ? -37.949 19.060 -28.026 1.00 78.90 ? 15 ASN A C 15 ASN A C 1 ATOM 112 O O . ASN A 1 15 ? -38.092 17.960 -28.562 1.00 78.90 ? 15 ASN A O 15 ASN A O 1 ATOM 113 C CB . ASN A 1 15 ? -37.474 19.137 -25.564 1.00 78.90 ? 15 ASN A CB 15 ASN A CB 1 ATOM 114 C CG . ASN A 1 15 ? -36.423 18.901 -24.498 1.00 78.90 ? 15 ASN A CG 15 ASN A CG 1 ATOM 115 O OD1 . ASN A 1 15 ? -35.353 18.352 -24.774 1.00 78.90 ? 15 ASN A OD1 15 ASN A OD1 1 ATOM 116 N ND2 . ASN A 1 15 ? -36.719 19.315 -23.271 1.00 78.90 ? 15 ASN A ND2 15 ASN A ND2 1 ATOM 117 N N . LEU A 1 16 ? -38.680 20.178 -28.372 1.00 78.78 ? 16 LEU A N 16 LEU A N 1 ATOM 118 C CA . LEU A 1 16 ? -39.696 20.095 -29.415 1.00 78.78 ? 16 LEU A CA 16 LEU A CA 1 ATOM 119 C C . LEU A 1 16 ? -39.056 19.884 -30.783 1.00 78.78 ? 16 LEU A C 16 LEU A C 1 ATOM 120 O O . LEU A 1 16 ? -39.569 19.116 -31.601 1.00 78.78 ? 16 LEU A O 16 LEU A O 1 ATOM 121 C CB . LEU A 1 16 ? -40.554 21.364 -29.430 1.00 78.78 ? 16 LEU A CB 16 LEU A CB 1 ATOM 122 C CG . LEU A 1 16 ? -41.862 21.307 -28.639 1.00 78.78 ? 16 LEU A CG 16 LEU A CG 1 ATOM 123 C CD1 . LEU A 1 16 ? -42.425 22.711 -28.447 1.00 78.78 ? 16 LEU A CD1 16 LEU A CD1 1 ATOM 124 C CD2 . LEU A 1 16 ? -42.875 20.411 -29.343 1.00 78.78 ? 16 LEU A CD2 16 LEU A CD2 1 ATOM 125 N N . HIS A 1 17 ? -37.830 20.563 -30.946 1.00 79.58 ? 17 HIS A N 17 HIS A N 1 ATOM 126 C CA . HIS A 1 17 ? -37.093 20.378 -32.191 1.00 79.58 ? 17 HIS A CA 17 HIS A CA 1 ATOM 127 C C . HIS A 1 17 ? -36.578 18.948 -32.319 1.00 79.58 ? 17 HIS A C 17 HIS A C 1 ATOM 128 O O . HIS A 1 17 ? -36.628 18.360 -33.402 1.00 79.58 ? 17 HIS A O 17 HIS A O 1 ATOM 129 C CB . HIS A 1 17 ? -35.927 21.365 -32.276 1.00 79.58 ? 17 HIS A CB 17 HIS A CB 1 ATOM 130 C CG . HIS A 1 17 ? -35.609 21.800 -33.671 1.00 79.58 ? 17 HIS A CG 17 HIS A CG 1 ATOM 131 N ND1 . HIS A 1 17 ? -34.697 21.140 -34.466 1.00 79.58 ? 17 HIS A ND1 17 HIS A ND1 1 ATOM 132 C CD2 . HIS A 1 17 ? -36.086 22.828 -34.412 1.00 79.58 ? 17 HIS A CD2 17 HIS A CD2 1 ATOM 133 C CE1 . HIS A 1 17 ? -34.626 21.746 -35.640 1.00 79.58 ? 17 HIS A CE1 17 HIS A CE1 1 ATOM 134 N NE2 . HIS A 1 17 ? -35.459 22.773 -35.632 1.00 79.58 ? 17 HIS A NE2 17 HIS A NE2 1 ATOM 135 N N . HIS A 1 18 ? -36.139 18.362 -31.133 1.00 81.97 ? 18 HIS A N 18 HIS A N 1 ATOM 136 C CA . HIS A 1 18 ? -35.677 16.978 -31.134 1.00 81.97 ? 18 HIS A CA 18 HIS A CA 1 ATOM 137 C C . HIS A 1 18 ? -36.826 16.014 -31.410 1.00 81.97 ? 18 HIS A C 18 HIS A C 1 ATOM 138 O O . HIS A 1 18 ? -36.661 15.041 -32.149 1.00 81.97 ? 18 HIS A O 18 HIS A O 1 ATOM 139 C CB . HIS A 1 18 ? -35.011 16.634 -29.801 1.00 81.97 ? 18 HIS A CB 18 HIS A CB 1 ATOM 140 C CG . HIS A 1 18 ? -33.531 16.853 -29.795 1.00 81.97 ? 18 HIS A CG 18 HIS A CG 1 ATOM 141 N ND1 . HIS A 1 18 ? -32.660 16.068 -30.519 1.00 81.97 ? 18 HIS A ND1 18 HIS A ND1 1 ATOM 142 C CD2 . HIS A 1 18 ? -32.771 17.772 -29.155 1.00 81.97 ? 18 HIS A CD2 18 HIS A CD2 1 ATOM 143 C CE1 . HIS A 1 18 ? -31.424 16.496 -30.322 1.00 81.97 ? 18 HIS A CE1 18 HIS A CE1 1 ATOM 144 N NE2 . HIS A 1 18 ? -31.464 17.529 -29.498 1.00 81.97 ? 18 HIS A NE2 18 HIS A NE2 1 ATOM 145 N N . LYS A 1 19 ? -38.008 16.366 -30.844 1.00 85.89 ? 19 LYS A N 19 LYS A N 1 ATOM 146 C CA . LYS A 1 19 ? -39.188 15.538 -31.076 1.00 85.89 ? 19 LYS A CA 19 LYS A CA 1 ATOM 147 C C . LYS A 1 19 ? -39.641 15.622 -32.530 1.00 85.89 ? 19 LYS A C 19 LYS A C 1 ATOM 148 O O . LYS A 1 19 ? -39.976 14.605 -33.141 1.00 85.89 ? 19 LYS A O 19 LYS A O 1 ATOM 149 C CB . LYS A 1 19 ? -40.329 15.957 -30.147 1.00 85.89 ? 19 LYS A CB 19 LYS A CB 1 ATOM 150 C CG . LYS A 1 19 ? -41.357 14.863 -29.897 1.00 85.89 ? 19 LYS A CG 19 LYS A CG 1 ATOM 151 C CD . LYS A 1 19 ? -42.375 15.282 -28.844 1.00 85.89 ? 19 LYS A CD 19 LYS A CD 1 ATOM 152 C CE . LYS A 1 19 ? -43.454 14.224 -28.656 1.00 85.89 ? 19 LYS A CE 19 LYS A CE 1 ATOM 153 N NZ . LYS A 1 19 ? -44.426 14.608 -27.589 1.00 85.89 ? 19 LYS A NZ 19 LYS A NZ 1 ATOM 154 N N . VAL A 1 20 ? -39.715 16.790 -33.157 1.00 85.43 ? 20 VAL A N 20 VAL A N 1 ATOM 155 C CA . VAL A 1 20 ? -40.104 16.985 -34.550 1.00 85.43 ? 20 VAL A CA 20 VAL A CA 1 ATOM 156 C C . VAL A 1 20 ? -39.112 16.275 -35.468 1.00 85.43 ? 20 VAL A C 20 VAL A C 1 ATOM 157 O O . VAL A 1 20 ? -39.508 15.638 -36.447 1.00 85.43 ? 20 VAL A O 20 VAL A O 1 ATOM 158 C CB . VAL A 1 20 ? -40.185 18.485 -34.912 1.00 85.43 ? 20 VAL A CB 20 VAL A CB 1 ATOM 159 C CG1 . VAL A 1 20 ? -40.344 18.668 -36.420 1.00 85.43 ? 20 VAL A CG1 20 VAL A CG1 1 ATOM 160 C CG2 . VAL A 1 20 ? -41.339 19.152 -34.165 1.00 85.43 ? 20 VAL A CG2 20 VAL A CG2 1 ATOM 161 N N . HIS A 1 21 ? -37.774 16.286 -35.091 1.00 84.61 ? 21 HIS A N 21 HIS A N 1 ATOM 162 C CA . HIS A 1 21 ? -36.748 15.609 -35.876 1.00 84.61 ? 21 HIS A CA 21 HIS A CA 1 ATOM 163 C C . HIS A 1 21 ? -36.918 14.095 -35.817 1.00 84.61 ? 21 HIS A C 21 HIS A C 1 ATOM 164 O O . HIS A 1 21 ? -36.767 13.409 -36.830 1.00 84.61 ? 21 HIS A O 21 HIS A O 1 ATOM 165 C CB . HIS A 1 21 ? -35.353 16.000 -35.385 1.00 84.61 ? 21 HIS A CB 21 HIS A CB 1 ATOM 166 C CG . HIS A 1 21 ? -34.284 15.830 -36.418 1.00 84.61 ? 21 HIS A CG 21 HIS A CG 1 ATOM 167 N ND1 . HIS A 1 21 ? -33.816 14.594 -36.808 1.00 84.61 ? 21 HIS A ND1 21 HIS A ND1 1 ATOM 168 C CD2 . HIS A 1 21 ? -33.595 16.743 -37.142 1.00 84.61 ? 21 HIS A CD2 21 HIS A CD2 1 ATOM 169 C CE1 . HIS A 1 21 ? -32.882 14.755 -37.731 1.00 84.61 ? 21 HIS A CE1 21 HIS A CE1 1 ATOM 170 N NE2 . HIS A 1 21 ? -32.729 16.050 -37.951 1.00 84.61 ? 21 HIS A NE2 21 HIS A NE2 1 ATOM 171 N N . SER A 1 22 ? -37.280 13.559 -34.654 1.00 85.29 ? 22 SER A N 22 SER A N 1 ATOM 172 C CA . SER A 1 22 ? -37.529 12.130 -34.498 1.00 85.29 ? 22 SER A CA 22 SER A CA 1 ATOM 173 C C . SER A 1 22 ? -38.755 11.692 -35.292 1.00 85.29 ? 22 SER A C 22 SER A C 1 ATOM 174 O O . SER A 1 22 ? -38.737 10.647 -35.945 1.00 85.29 ? 22 SER A O 22 SER A O 1 ATOM 175 C CB . SER A 1 22 ? -37.716 11.776 -33.022 1.00 85.29 ? 22 SER A CB 22 SER A CB 1 ATOM 176 O OG . SER A 1 22 ? -38.488 10.596 -32.881 1.00 85.29 ? 22 SER A OG 22 SER A OG 1 ATOM 177 N N . LEU A 1 23 ? -39.845 12.513 -35.278 1.00 84.45 ? 23 LEU A N 23 LEU A N 1 ATOM 178 C CA . LEU A 1 23 ? -41.065 12.191 -36.011 1.00 84.45 ? 23 LEU A CA 23 LEU A CA 1 ATOM 179 C C . LEU A 1 23 ? -40.835 12.283 -37.516 1.00 84.45 ? 23 LEU A C 23 LEU A C 1 ATOM 180 O O . LEU A 1 23 ? -41.356 11.466 -38.279 1.00 84.45 ? 23 LEU A O 23 LEU A O 1 ATOM 181 C CB . LEU A 1 23 ? -42.202 13.129 -35.598 1.00 84.45 ? 23 LEU A CB 23 LEU A CB 1 ATOM 182 C CG . LEU A 1 23 ? -42.900 12.807 -34.276 1.00 84.45 ? 23 LEU A CG 23 LEU A CG 1 ATOM 183 C CD1 . LEU A 1 23 ? -43.888 13.912 -33.916 1.00 84.45 ? 23 LEU A CD1 23 LEU A CD1 1 ATOM 184 C CD2 . LEU A 1 23 ? -43.605 11.458 -34.357 1.00 84.45 ? 23 LEU A CD2 23 LEU A CD2 1 ATOM 185 N N . ASN A 1 24 ? -40.056 13.288 -37.987 1.00 83.49 ? 24 ASN A N 24 ASN A N 1 ATOM 186 C CA . ASN A 1 24 ? -39.708 13.401 -39.399 1.00 83.49 ? 24 ASN A CA 24 ASN A CA 1 ATOM 187 C C . ASN A 1 24 ? -38.905 12.195 -39.878 1.00 83.49 ? 24 ASN A C 24 ASN A C 1 ATOM 188 O O . ASN A 1 24 ? -39.101 11.719 -40.997 1.00 83.49 ? 24 ASN A O 24 ASN A O 1 ATOM 189 C CB . ASN A 1 24 ? -38.930 14.693 -39.658 1.00 83.49 ? 24 ASN A CB 24 ASN A CB 1 ATOM 190 C CG . ASN A 1 24 ? -39.834 15.902 -39.798 1.00 83.49 ? 24 ASN A CG 24 ASN A CG 1 ATOM 191 O OD1 . ASN A 1 24 ? -41.052 15.768 -39.938 1.00 83.49 ? 24 ASN A OD1 24 ASN A OD1 1 ATOM 192 N ND2 . ASN A 1 24 ? -39.245 17.091 -39.759 1.00 83.49 ? 24 ASN A ND2 24 ASN A ND2 1 ATOM 193 N N . LYS A 1 25 ? -37.993 11.663 -39.030 1.00 84.94 ? 25 LYS A N 25 LYS A N 1 ATOM 194 C CA . LYS A 1 25 ? -37.216 10.477 -39.380 1.00 84.94 ? 25 LYS A CA 25 LYS A CA 1 ATOM 195 C C . LYS A 1 25 ? -38.116 9.254 -39.525 1.00 84.94 ? 25 LYS A C 25 LYS A C 1 ATOM 196 O O . LYS A 1 25 ? -37.931 8.446 -40.438 1.00 84.94 ? 25 LYS A O 25 LYS A O 1 ATOM 197 C CB . LYS A 1 25 ? -36.138 10.213 -38.328 1.00 84.94 ? 25 LYS A CB 25 LYS A CB 1 ATOM 198 C CG . LYS A 1 25 ? -34.844 10.977 -38.563 1.00 84.94 ? 25 LYS A CG 25 LYS A CG 1 ATOM 199 C CD . LYS A 1 25 ? -33.765 10.569 -37.568 1.00 84.94 ? 25 LYS A CD 25 LYS A CD 1 ATOM 200 C CE . LYS A 1 25 ? -32.498 11.395 -37.744 1.00 84.94 ? 25 LYS A CE 25 LYS A CE 1 ATOM 201 N NZ . LYS A 1 25 ? -31.433 10.990 -36.778 1.00 84.94 ? 25 LYS A NZ 25 LYS A NZ 1 ATOM 202 N N . LYS A 1 26 ? -39.137 9.151 -38.670 1.00 79.59 ? 26 LYS A N 26 LYS A N 1 ATOM 203 C CA . LYS A 1 26 ? -40.086 8.044 -38.752 1.00 79.59 ? 26 LYS A CA 26 LYS A CA 1 ATOM 204 C C . LYS A 1 26 ? -40.923 8.131 -40.025 1.00 79.59 ? 26 LYS A C 26 LYS A C 1 ATOM 205 O O . LYS A 1 26 ? -41.165 7.118 -40.685 1.00 79.59 ? 26 LYS A O 26 LYS A O 1 ATOM 206 C CB . LYS A 1 26 ? -40.999 8.027 -37.525 1.00 79.59 ? 26 LYS A CB 26 LYS A CB 1 ATOM 207 C CG . LYS A 1 26 ? -40.367 7.398 -36.292 1.00 79.59 ? 26 LYS A CG 26 LYS A CG 1 ATOM 208 C CD . LYS A 1 26 ? -41.367 7.284 -35.149 1.00 79.59 ? 26 LYS A CD 26 LYS A CD 1 ATOM 209 C CE . LYS A 1 26 ? -40.717 6.722 -33.891 1.00 79.59 ? 26 LYS A CE 26 LYS A CE 1 ATOM 210 N NZ . LYS A 1 26 ? -41.686 6.638 -32.758 1.00 79.59 ? 26 LYS A NZ 26 LYS A NZ 1 ATOM 211 N N . ARG A 1 27 ? -41.368 9.399 -40.355 1.00 77.93 ? 27 ARG A N 27 ARG A N 1 ATOM 212 C CA . ARG A 1 27 ? -42.121 9.602 -41.588 1.00 77.93 ? 27 ARG A CA 27 ARG A CA 1 ATOM 213 C C . ARG A 1 27 ? -41.266 9.283 -42.810 1.00 77.93 ? 27 ARG A C 27 ARG A C 1 ATOM 214 O O . ARG A 1 27 ? -41.745 8.670 -43.766 1.00 77.93 ? 27 ARG A O 27 ARG A O 1 ATOM 215 C CB . ARG A 1 27 ? -42.639 11.040 -41.672 1.00 77.93 ? 27 ARG A CB 27 ARG A CB 1 ATOM 216 C CG . ARG A 1 27 ? -44.154 11.153 -41.613 1.00 77.93 ? 27 ARG A CG 27 ARG A CG 1 ATOM 217 C CD . ARG A 1 27 ? -44.620 12.589 -41.806 1.00 77.93 ? 27 ARG A CD 27 ARG A CD 1 ATOM 218 N NE . ARG A 1 27 ? -44.739 13.293 -40.532 1.00 77.93 ? 27 ARG A NE 27 ARG A NE 1 ATOM 219 C CZ . ARG A 1 27 ? -44.914 14.605 -40.404 1.00 77.93 ? 27 ARG A CZ 27 ARG A CZ 1 ATOM 220 N NH1 . ARG A 1 27 ? -44.994 15.386 -41.476 1.00 77.93 ? 27 ARG A NH1 27 ARG A NH1 1 ATOM 221 N NH2 . ARG A 1 27 ? -45.010 15.141 -39.196 1.00 77.93 ? 27 ARG A NH2 27 ARG A NH2 1 ATOM 222 N N . ALA A 1 28 ? -39.961 9.729 -42.791 1.00 76.16 ? 28 ALA A N 28 ALA A N 1 ATOM 223 C CA . ALA A 1 28 ? -39.045 9.435 -43.891 1.00 76.16 ? 28 ALA A CA 28 ALA A CA 1 ATOM 224 C C . ALA A 1 28 ? -38.816 7.932 -44.026 1.00 76.16 ? 28 ALA A C 28 ALA A C 1 ATOM 225 O O . ALA A 1 28 ? -38.726 7.410 -45.140 1.00 76.16 ? 28 ALA A O 28 ALA A O 1 ATOM 226 C CB . ALA A 1 28 ? -37.716 10.156 -43.684 1.00 76.16 ? 28 ALA A CB 28 ALA A CB 1 ATOM 227 N N . GLN A 1 29 ? -38.693 7.208 -42.854 1.00 72.55 ? 29 GLN A N 29 GLN A N 1 ATOM 228 C CA . GLN A 1 29 ? -38.501 5.762 -42.866 1.00 72.55 ? 29 GLN A CA 29 GLN A CA 1 ATOM 229 C C . GLN A 1 29 ? -39.718 5.050 -43.450 1.00 72.55 ? 29 GLN A C 29 GLN A C 1 ATOM 230 O O . GLN A 1 29 ? -39.576 4.080 -44.198 1.00 72.55 ? 29 GLN A O 29 GLN A O 1 ATOM 231 C CB . GLN A 1 29 ? -38.218 5.245 -41.455 1.00 72.55 ? 29 GLN A CB 29 GLN A CB 1 ATOM 232 C CG . GLN A 1 29 ? -36.792 4.748 -41.256 1.00 72.55 ? 29 GLN A CG 29 GLN A CG 1 ATOM 233 C CD . GLN A 1 29 ? -36.528 4.274 -39.839 1.00 72.55 ? 29 GLN A CD 29 GLN A CD 1 ATOM 234 O OE1 . GLN A 1 29 ? -37.424 4.284 -38.990 1.00 72.55 ? 29 GLN A OE1 29 GLN A OE1 1 ATOM 235 N NE2 . GLN A 1 29 ? -35.294 3.857 -39.574 1.00 72.55 ? 29 GLN A NE2 29 GLN A NE2 1 ATOM 236 N N . ARG A 1 30 ? -40.916 5.595 -43.115 1.00 68.66 ? 30 ARG A N 30 ARG A N 1 ATOM 237 C CA . ARG A 1 30 ? -42.145 5.042 -43.675 1.00 68.66 ? 30 ARG A CA 30 ARG A CA 1 ATOM 238 C C . ARG A 1 30 ? -42.217 5.281 -45.179 1.00 68.66 ? 30 ARG A C 30 ARG A C 1 ATOM 239 O O . ARG A 1 30 ? -42.659 4.410 -45.931 1.00 68.66 ? 30 ARG A O 30 ARG A O 1 ATOM 240 C CB . ARG A 1 30 ? -43.370 5.650 -42.989 1.00 68.66 ? 30 ARG A CB 30 ARG A CB 1 ATOM 241 C CG . ARG A 1 30 ? -44.026 4.730 -41.971 1.00 68.66 ? 30 ARG A CG 30 ARG A CG 1 ATOM 242 C CD . ARG A 1 30 ? -45.321 5.318 -41.430 1.00 68.66 ? 30 ARG A CD 30 ARG A CD 1 ATOM 243 N NE . ARG A 1 30 ? -45.128 5.934 -40.120 1.00 68.66 ? 30 ARG A NE 30 ARG A NE 1 ATOM 244 C CZ . ARG A 1 30 ? -45.995 6.753 -39.532 1.00 68.66 ? 30 ARG A CZ 30 ARG A CZ 1 ATOM 245 N NH1 . ARG A 1 30 ? -47.137 7.073 -40.129 1.00 68.66 ? 30 ARG A NH1 30 ARG A NH1 1 ATOM 246 N NH2 . ARG A 1 30 ? -45.718 7.257 -38.338 1.00 68.66 ? 30 ARG A NH2 30 ARG A NH2 1 ATOM 247 N N . GLU A 1 31 ? -41.774 6.546 -45.569 1.00 71.11 ? 31 GLU A N 31 GLU A N 1 ATOM 248 C CA . GLU A 1 31 ? -41.735 6.855 -46.995 1.00 71.11 ? 31 GLU A CA 31 GLU A CA 1 ATOM 249 C C . GLU A 1 31 ? -40.694 6.003 -47.716 1.00 71.11 ? 31 GLU A C 31 GLU A C 1 ATOM 250 O O . GLU A 1 31 ? -40.936 5.528 -48.827 1.00 71.11 ? 31 GLU A O 31 GLU A O 1 ATOM 251 C CB . GLU A 1 31 ? -41.441 8.341 -47.215 1.00 71.11 ? 31 GLU A CB 31 GLU A CB 1 ATOM 252 C CG . GLU A 1 31 ? -41.752 8.828 -48.623 1.00 71.11 ? 31 GLU A CG 31 GLU A CG 1 ATOM 253 C CD . GLU A 1 31 ? -41.519 10.319 -48.808 1.00 71.11 ? 31 GLU A CD 31 GLU A CD 1 ATOM 254 O OE1 . GLU A 1 31 ? -41.610 10.810 -49.956 1.00 71.11 ? 31 GLU A OE1 31 GLU A OE1 1 ATOM 255 O OE2 . GLU A 1 31 ? -41.242 11.002 -47.796 1.00 71.11 ? 31 GLU A OE2 31 GLU A OE2 1 ATOM 256 N N . ARG A 1 32 ? -39.446 5.793 -47.018 1.00 63.75 ? 32 ARG A N 32 ARG A N 1 ATOM 257 C CA . ARG A 1 32 ? -38.367 4.992 -47.588 1.00 63.75 ? 32 ARG A CA 32 ARG A CA 1 ATOM 258 C C . ARG A 1 32 ? -38.760 3.521 -47.663 1.00 63.75 ? 32 ARG A C 32 ARG A C 1 ATOM 259 O O . ARG A 1 32 ? -38.385 2.821 -48.606 1.00 63.75 ? 32 ARG A O 32 ARG A O 1 ATOM 260 C CB . ARG A 1 32 ? -37.087 5.152 -46.765 1.00 63.75 ? 32 ARG A CB 32 ARG A CB 1 ATOM 261 C CG . ARG A 1 32 ? -35.832 5.327 -47.607 1.00 63.75 ? 32 ARG A CG 32 ARG A CG 1 ATOM 262 C CD . ARG A 1 32 ? -34.599 5.545 -46.742 1.00 63.75 ? 32 ARG A CD 32 ARG A CD 1 ATOM 263 N NE . ARG A 1 32 ? -33.410 5.797 -47.551 1.00 63.75 ? 32 ARG A NE 32 ARG A NE 1 ATOM 264 C CZ . ARG A 1 32 ? -32.353 6.496 -47.148 1.00 63.75 ? 32 ARG A CZ 32 ARG A CZ 1 ATOM 265 N NH1 . ARG A 1 32 ? -32.315 7.028 -45.932 1.00 63.75 ? 32 ARG A NH1 32 ARG A NH1 1 ATOM 266 N NH2 . ARG A 1 32 ? -31.325 6.664 -47.967 1.00 63.75 ? 32 ARG A NH2 32 ARG A NH2 1 ATOM 267 N N . ALA A 1 33 ? -39.501 3.113 -46.626 1.00 62.50 ? 33 ALA A N 33 ALA A N 1 ATOM 268 C CA . ALA A 1 33 ? -39.916 1.712 -46.607 1.00 62.50 ? 33 ALA A CA 33 ALA A CA 1 ATOM 269 C C . ALA A 1 33 ? -41.028 1.456 -47.620 1.00 62.50 ? 33 ALA A C 33 ALA A C 1 ATOM 270 O O . ALA A 1 33 ? -41.427 0.309 -47.837 1.00 62.50 ? 33 ALA A O 33 ALA A O 1 ATOM 271 C CB . ALA A 1 33 ? -40.372 1.311 -45.207 1.00 62.50 ? 33 ALA A CB 33 ALA A CB 1 ATOM 272 N N . GLY A 1 34 ? -41.230 2.460 -48.638 1.00 47.43 ? 34 GLY A N 34 GLY A N 1 ATOM 273 C CA . GLY A 1 34 ? -41.929 2.309 -49.904 1.00 47.43 ? 34 GLY A CA 34 GLY A CA 1 ATOM 274 C C . GLY A 1 34 ? -43.368 1.858 -49.742 1.00 47.43 ? 34 GLY A C 34 GLY A C 1 ATOM 275 O O . GLY A 1 34 ? -43.678 1.062 -48.853 1.00 47.43 ? 34 GLY A O 34 GLY A O 1 ATOM 276 N N . LEU A 1 35 ? -44.458 2.723 -49.959 1.00 49.68 ? 35 LEU A N 35 LEU A N 1 ATOM 277 C CA . LEU A 1 35 ? -45.896 2.758 -50.201 1.00 49.68 ? 35 LEU A CA 35 LEU A CA 1 ATOM 278 C C . LEU A 1 35 ? -46.355 1.498 -50.928 1.00 49.68 ? 35 LEU A C 35 LEU A C 1 ATOM 279 O O . LEU A 1 35 ? -47.557 1.252 -51.053 1.00 49.68 ? 35 LEU A O 35 LEU A O 1 ATOM 280 C CB . LEU A 1 35 ? -46.273 3.997 -51.017 1.00 49.68 ? 35 LEU A CB 35 LEU A CB 1 ATOM 281 C CG . LEU A 1 35 ? -47.010 5.106 -50.264 1.00 49.68 ? 35 LEU A CG 35 LEU A CG 1 ATOM 282 C CD1 . LEU A 1 35 ? -46.030 6.184 -49.814 1.00 49.68 ? 35 LEU A CD1 35 LEU A CD1 1 ATOM 283 C CD2 . LEU A 1 35 ? -48.109 5.705 -51.136 1.00 49.68 ? 35 LEU A CD2 35 LEU A CD2 1 ATOM 284 N N . LEU A 1 36 ? -45.420 0.426 -51.029 1.00 44.84 ? 36 LEU A N 36 LEU A N 1 ATOM 285 C CA . LEU A 1 36 ? -45.934 -0.696 -51.806 1.00 44.84 ? 36 LEU A CA 36 LEU A CA 1 ATOM 286 C C . LEU A 1 36 ? -46.031 -1.953 -50.948 1.00 44.84 ? 36 LEU A C 36 LEU A C 1 ATOM 287 O O . LEU A 1 36 ? -45.775 -3.060 -51.429 1.00 44.84 ? 36 LEU A O 36 LEU A O 1 ATOM 288 C CB . LEU A 1 36 ? -45.041 -0.961 -53.021 1.00 44.84 ? 36 LEU A CB 36 LEU A CB 1 ATOM 289 C CG . LEU A 1 36 ? -45.242 -0.039 -54.225 1.00 44.84 ? 36 LEU A CG 36 LEU A CG 1 ATOM 290 C CD1 . LEU A 1 36 ? -43.964 0.038 -55.053 1.00 44.84 ? 36 LEU A CD1 36 LEU A CD1 1 ATOM 291 C CD2 . LEU A 1 36 ? -46.411 -0.519 -55.078 1.00 44.84 ? 36 LEU A CD2 36 LEU A CD2 1 ATOM 292 N N . LYS A 1 37 ? -46.240 -1.792 -49.573 1.00 51.35 ? 37 LYS A N 37 LYS A N 1 ATOM 293 C CA . LYS A 1 37 ? -46.587 -3.041 -48.903 1.00 51.35 ? 37 LYS A CA 37 LYS A CA 1 ATOM 294 C C . LYS A 1 37 ? -48.076 -3.346 -49.046 1.00 51.35 ? 37 LYS A C 37 LYS A C 1 ATOM 295 O O . LYS A 1 37 ? -48.901 -2.431 -49.088 1.00 51.35 ? 37 LYS A O 37 LYS A O 1 ATOM 296 C CB . LYS A 1 37 ? -46.204 -2.983 -47.424 1.00 51.35 ? 37 LYS A CB 37 LYS A CB 1 ATOM 297 C CG . LYS A 1 37 ? -44.704 -3.020 -47.171 1.00 51.35 ? 37 LYS A CG 37 LYS A CG 1 ATOM 298 C CD . LYS A 1 37 ? -44.391 -3.278 -45.703 1.00 51.35 ? 37 LYS A CD 37 LYS A CD 1 ATOM 299 C CE . LYS A 1 37 ? -42.891 -3.378 -45.459 1.00 51.35 ? 37 LYS A CE 37 LYS A CE 1 ATOM 300 N NZ . LYS A 1 37 ? -42.576 -3.566 -44.012 1.00 51.35 ? 37 LYS A NZ 37 LYS A NZ 1 ATOM 301 N N . PRO A 1 38 ? -48.400 -4.598 -49.547 1.00 54.51 ? 38 PRO A N 38 PRO A N 1 ATOM 302 C CA . PRO A 1 38 ? -49.792 -5.009 -49.749 1.00 54.51 ? 38 PRO A CA 38 PRO A CA 1 ATOM 303 C C . PRO A 1 38 ? -50.650 -4.821 -48.500 1.00 54.51 ? 38 PRO A C 38 PRO A C 1 ATOM 304 O O . PRO A 1 38 ? -50.121 -4.763 -47.387 1.00 54.51 ? 38 PRO A O 38 PRO A O 1 ATOM 305 C CB . PRO A 1 38 ? -49.673 -6.491 -50.112 1.00 54.51 ? 38 PRO A CB 38 PRO A CB 1 ATOM 306 C CG . PRO A 1 38 ? -48.284 -6.872 -49.710 1.00 54.51 ? 38 PRO A CG 38 PRO A CG 1 ATOM 307 C CD . PRO A 1 38 ? -47.497 -5.617 -49.467 1.00 54.51 ? 38 PRO A CD 38 PRO A CD 1 ATOM 308 N N . ALA A 1 39 ? -51.779 -4.212 -48.692 1.00 55.82 ? 39 ALA A N 39 ALA A N 1 ATOM 309 C CA . ALA A 1 39 ? -52.807 -3.927 -47.694 1.00 55.82 ? 39 ALA A CA 39 ALA A CA 1 ATOM 310 C C . ALA A 1 39 ? -53.014 -5.118 -46.764 1.00 55.82 ? 39 ALA A C 39 ALA A C 1 ATOM 311 O O . ALA A 1 39 ? -52.827 -6.268 -47.167 1.00 55.82 ? 39 ALA A O 39 ALA A O 1 ATOM 312 C CB . ALA A 1 39 ? -54.121 -3.553 -48.376 1.00 55.82 ? 39 ALA A CB 39 ALA A CB 1 ATOM 313 N N . ARG A 1 40 ? -52.893 -4.891 -45.510 1.00 50.22 ? 40 ARG A N 40 ARG A N 1 ATOM 314 C CA . ARG A 1 40 ? -52.992 -5.819 -44.389 1.00 50.22 ? 40 ARG A CA 40 ARG A CA 1 ATOM 315 C C . ARG A 1 40 ? -53.973 -6.946 -44.695 1.00 50.22 ? 40 ARG A C 40 ARG A C 1 ATOM 316 O O . ARG A 1 40 ? -53.781 -8.081 -44.254 1.00 50.22 ? 40 ARG A O 40 ARG A O 1 ATOM 317 C CB . ARG A 1 40 ? -53.420 -5.084 -43.117 1.00 50.22 ? 40 ARG A CB 40 ARG A CB 1 ATOM 318 C CG . ARG A 1 40 ? -52.485 -5.299 -41.937 1.00 50.22 ? 40 ARG A CG 40 ARG A CG 1 ATOM 319 C CD . ARG A 1 40 ? -52.946 -4.532 -40.705 1.00 50.22 ? 40 ARG A CD 40 ARG A CD 1 ATOM 320 N NE . ARG A 1 40 ? -52.223 -4.951 -39.508 1.00 50.22 ? 40 ARG A NE 40 ARG A NE 1 ATOM 321 C CZ . ARG A 1 40 ? -52.382 -4.416 -38.300 1.00 50.22 ? 40 ARG A CZ 40 ARG A CZ 1 ATOM 322 N NH1 . ARG A 1 40 ? -53.247 -3.427 -38.105 1.00 50.22 ? 40 ARG A NH1 40 ARG A NH1 1 ATOM 323 N NH2 . ARG A 1 40 ? -51.673 -4.874 -37.280 1.00 50.22 ? 40 ARG A NH2 40 ARG A NH2 1 ATOM 324 N N . SER A 1 41 ? -54.831 -6.715 -45.648 1.00 54.53 ? 41 SER A N 41 SER A N 1 ATOM 325 C CA . SER A 1 41 ? -55.813 -7.766 -45.896 1.00 54.53 ? 41 SER A CA 41 SER A CA 1 ATOM 326 C C . SER A 1 41 ? -55.353 -8.700 -47.011 1.00 54.53 ? 41 SER A C 41 SER A C 1 ATOM 327 O O . SER A 1 41 ? -55.999 -9.714 -47.285 1.00 54.53 ? 41 SER A O 41 SER A O 1 ATOM 328 C CB . SER A 1 41 ? -57.170 -7.159 -46.255 1.00 54.53 ? 41 SER A CB 41 SER A CB 1 ATOM 329 O OG . SER A 1 41 ? -57.062 -6.330 -47.399 1.00 54.53 ? 41 SER A OG 41 SER A OG 1 ATOM 330 N N . SER A 1 42 ? -54.227 -8.342 -47.648 1.00 55.66 ? 42 SER A N 42 SER A N 1 ATOM 331 C CA . SER A 1 42 ? -53.796 -9.196 -48.750 1.00 55.66 ? 42 SER A CA 42 SER A CA 1 ATOM 332 C C . SER A 1 42 ? -53.168 -10.487 -48.236 1.00 55.66 ? 42 SER A C 42 SER A C 1 ATOM 333 O O . SER A 1 42 ? -52.664 -10.534 -47.112 1.00 55.66 ? 42 SER A O 42 SER A O 1 ATOM 334 C CB . SER A 1 42 ? -52.801 -8.456 -49.644 1.00 55.66 ? 42 SER A CB 42 SER A CB 1 ATOM 335 O OG . SER A 1 42 ? -51.488 -8.544 -49.117 1.00 55.66 ? 42 SER A OG 42 SER A OG 1 ATOM 336 N N . VAL A 1 43 ? -53.566 -11.537 -48.908 1.00 56.09 ? 43 VAL A N 43 VAL A N 1 ATOM 337 C CA . VAL A 1 43 ? -53.120 -12.882 -48.560 1.00 56.09 ? 43 VAL A CA 43 VAL A CA 1 ATOM 338 C C . VAL A 1 43 ? -51.594 -12.930 -48.533 1.00 56.09 ? 43 VAL A C 43 VAL A C 1 ATOM 339 O O . VAL A 1 43 ? -51.003 -13.678 -47.751 1.00 56.09 ? 43 VAL A O 43 VAL A O 1 ATOM 340 C CB . VAL A 1 43 ? -53.669 -13.936 -49.547 1.00 56.09 ? 43 VAL A CB 43 VAL A CB 1 ATOM 341 C CG1 . VAL A 1 43 ? -53.198 -15.336 -49.159 1.00 56.09 ? 43 VAL A CG1 43 VAL A CG1 1 ATOM 342 C CG2 . VAL A 1 43 ? -55.195 -13.877 -49.595 1.00 56.09 ? 43 VAL A CG2 43 VAL A CG2 1 ATOM 343 N N . ASN A 1 44 ? -50.992 -11.867 -49.206 1.00 54.97 ? 44 ASN A N 44 ASN A N 1 ATOM 344 C CA . ASN A 1 44 ? -49.535 -11.850 -49.125 1.00 54.97 ? 44 ASN A CA 44 ASN A CA 1 ATOM 345 C C . ASN A 1 44 ? -49.044 -10.873 -48.060 1.00 54.97 ? 44 ASN A C 44 ASN A C 1 ATOM 346 O O . ASN A 1 44 ? -47.840 -10.651 -47.923 1.00 54.97 ? 44 ASN A O 44 ASN A O 1 ATOM 347 C CB . ASN A 1 44 ? -48.925 -11.503 -50.485 1.00 54.97 ? 44 ASN A CB 44 ASN A CB 1 ATOM 348 C CG . ASN A 1 44 ? -48.958 -12.669 -51.453 1.00 54.97 ? 44 ASN A CG 44 ASN A CG 1 ATOM 349 O OD1 . ASN A 1 44 ? -49.278 -13.798 -51.074 1.00 54.97 ? 44 ASN A OD1 44 ASN A OD1 1 ATOM 350 N ND2 . ASN A 1 44 ? -48.627 -12.403 -52.712 1.00 54.97 ? 44 ASN A ND2 44 ASN A ND2 1 ATOM 351 N N . SER A 1 45 ? -50.067 -10.403 -47.218 1.00 52.70 ? 45 SER A N 45 SER A N 1 ATOM 352 C CA . SER A 1 45 ? -49.721 -9.426 -46.191 1.00 52.70 ? 45 SER A CA 45 SER A CA 1 ATOM 353 C C . SER A 1 45 ? -49.294 -10.112 -44.897 1.00 52.70 ? 45 SER A C 45 SER A C 1 ATOM 354 O O . SER A 1 45 ? -49.918 -11.086 -44.469 1.00 52.70 ? 45 SER A O 45 SER A O 1 ATOM 355 C CB . SER A 1 45 ? -50.901 -8.494 -45.918 1.00 52.70 ? 45 SER A CB 45 SER A CB 1 ATOM 356 O OG . SER A 1 45 ? -50.656 -7.693 -44.774 1.00 52.70 ? 45 SER A OG 45 SER A OG 1 ATOM 357 N N . LYS A 1 46 ? -48.001 -9.975 -44.528 1.00 54.98 ? 46 LYS A N 46 LYS A N 1 ATOM 358 C CA . LYS A 1 46 ? -47.402 -10.570 -43.337 1.00 54.98 ? 46 LYS A CA 46 LYS A CA 1 ATOM 359 C C . LYS A 1 46 ? -47.656 -9.708 -42.104 1.00 54.98 ? 46 LYS A C 46 LYS A C 1 ATOM 360 O O . LYS A 1 46 ? -47.035 -9.911 -41.059 1.00 54.98 ? 46 LYS A O 46 LYS A O 1 ATOM 361 C CB . LYS A 1 46 ? -45.899 -10.771 -43.535 1.00 54.98 ? 46 LYS A CB 46 LYS A CB 1 ATOM 362 C CG . LYS A 1 46 ? -45.547 -11.835 -44.565 1.00 54.98 ? 46 LYS A CG 46 LYS A CG 1 ATOM 363 C CD . LYS A 1 46 ? -44.060 -12.165 -44.542 1.00 54.98 ? 46 LYS A CD 46 LYS A CD 1 ATOM 364 C CE . LYS A 1 46 ? -43.715 -13.260 -45.542 1.00 54.98 ? 46 LYS A CE 46 LYS A CE 1 ATOM 365 N NZ . LYS A 1 46 ? -42.264 -13.612 -45.499 1.00 54.98 ? 46 LYS A NZ 46 LYS A NZ 1 ATOM 366 N N . SER A 1 47 ? -48.624 -8.712 -42.260 1.00 51.47 ? 47 SER A N 47 SER A N 1 ATOM 367 C CA . SER A 1 47 ? -48.985 -7.788 -41.189 1.00 51.47 ? 47 SER A CA 47 SER A CA 1 ATOM 368 C C . SER A 1 47 ? -49.893 -8.459 -40.163 1.00 51.47 ? 47 SER A C 47 SER A C 1 ATOM 369 O O . SER A 1 47 ? -50.887 -9.090 -40.525 1.00 51.47 ? 47 SER A O 47 SER A O 1 ATOM 370 C CB . SER A 1 47 ? -49.676 -6.549 -41.760 1.00 51.47 ? 47 SER A CB 47 SER A CB 1 ATOM 371 O OG . SER A 1 47 ? -50.958 -6.877 -42.267 1.00 51.47 ? 47 SER A OG 47 SER A OG 1 ATOM 372 N N . GLY A 1 48 ? -49.414 -9.174 -39.240 1.00 50.35 ? 48 GLY A N 48 GLY A N 1 ATOM 373 C CA . GLY A 1 48 ? -49.958 -9.786 -38.038 1.00 50.35 ? 48 GLY A CA 48 GLY A CA 1 ATOM 374 C C . GLY A 1 48 ? -49.254 -11.073 -37.652 1.00 50.35 ? 48 GLY A C 48 GLY A C 1 ATOM 375 O O . GLY A 1 48 ? -49.601 -11.700 -36.649 1.00 50.35 ? 48 GLY A O 48 GLY A O 1 ATOM 376 N N . GLU A 1 49 ? -48.263 -11.415 -38.482 1.00 49.11 ? 49 GLU A N 49 GLU A N 1 ATOM 377 C CA . GLU A 1 49 ? -47.477 -12.581 -38.089 1.00 49.11 ? 49 GLU A CA 49 GLU A CA 1 ATOM 378 C C . GLU A 1 49 ? -46.293 -12.179 -37.214 1.00 49.11 ? 49 GLU A C 49 GLU A C 1 ATOM 379 O O . GLU A 1 49 ? -45.748 -11.083 -37.363 1.00 49.11 ? 49 GLU A O 49 GLU A O 1 ATOM 380 C CB . GLU A 1 49 ? -46.985 -13.339 -39.325 1.00 49.11 ? 49 GLU A CB 49 GLU A CB 1 ATOM 381 C CG . GLU A 1 49 ? -48.070 -14.143 -40.026 1.00 49.11 ? 49 GLU A CG 49 GLU A CG 1 ATOM 382 C CD . GLU A 1 49 ? -47.542 -14.995 -41.169 1.00 49.11 ? 49 GLU A CD 49 GLU A CD 1 ATOM 383 O OE1 . GLU A 1 49 ? -48.310 -15.815 -41.720 1.00 49.11 ? 49 GLU A OE1 49 GLU A OE1 1 ATOM 384 O OE2 . GLU A 1 49 ? -46.349 -14.841 -41.516 1.00 49.11 ? 49 GLU A OE2 49 GLU A OE2 1 ATOM 385 N N . ILE A 1 50 ? -46.288 -12.635 -35.938 1.00 47.34 ? 50 ILE A N 50 ILE A N 1 ATOM 386 C CA . ILE A 1 50 ? -45.342 -12.449 -34.843 1.00 47.34 ? 50 ILE A CA 50 ILE A CA 1 ATOM 387 C C . ILE A 1 50 ? -43.914 -12.551 -35.373 1.00 47.34 ? 50 ILE A C 50 ILE A C 1 ATOM 388 O O . ILE A 1 50 ? -43.558 -13.532 -36.030 1.00 47.34 ? 50 ILE A O 50 ILE A O 1 ATOM 389 C CB . ILE A 1 50 ? -45.572 -13.481 -33.716 1.00 47.34 ? 50 ILE A CB 50 ILE A CB 1 ATOM 390 C CG1 . ILE A 1 50 ? -46.998 -13.364 -33.168 1.00 47.34 ? 50 ILE A CG1 50 ILE A CG1 1 ATOM 391 C CG2 . ILE A 1 50 ? -44.539 -13.300 -32.600 1.00 47.34 ? 50 ILE A CG2 50 ILE A CG2 1 ATOM 392 C CD1 . ILE A 1 50 ? -47.462 -14.585 -32.385 1.00 47.34 ? 50 ILE A CD1 50 ILE A CD1 1 ATOM 393 N N . LYS A 1 51 ? -43.341 -11.428 -35.940 1.00 45.12 ? 51 LYS A N 51 LYS A N 1 ATOM 394 C CA . LYS A 1 51 ? -42.023 -11.299 -36.553 1.00 45.12 ? 51 LYS A CA 51 LYS A CA 1 ATOM 395 C C . LYS A 1 51 ? -40.937 -11.137 -35.493 1.00 45.12 ? 51 LYS A C 51 LYS A C 1 ATOM 396 O O . LYS A 1 51 ? -41.091 -10.352 -34.554 1.00 45.12 ? 51 LYS A O 51 LYS A O 1 ATOM 397 C CB . LYS A 1 51 ? -41.993 -10.114 -37.519 1.00 45.12 ? 51 LYS A CB 51 LYS A CB 1 ATOM 398 C CG . LYS A 1 51 ? -42.530 -10.433 -38.907 1.00 45.12 ? 51 LYS A CG 51 LYS A CG 1 ATOM 399 C CD . LYS A 1 51 ? -42.405 -9.238 -39.843 1.00 45.12 ? 51 LYS A CD 51 LYS A CD 1 ATOM 400 C CE . LYS A 1 51 ? -42.920 -9.563 -41.238 1.00 45.12 ? 51 LYS A CE 51 LYS A CE 1 ATOM 401 N NZ . LYS A 1 51 ? -42.774 -8.403 -42.167 1.00 45.12 ? 51 LYS A NZ 51 LYS A NZ 1 ATOM 402 N N . SER A 1 52 ? -40.178 -12.114 -35.165 1.00 47.72 ? 52 SER A N 52 SER A N 1 ATOM 403 C CA . SER A 1 52 ? -38.891 -11.888 -34.515 1.00 47.72 ? 52 SER A CA 52 SER A CA 1 ATOM 404 C C . SER A 1 52 ? -37.788 -11.654 -35.541 1.00 47.72 ? 52 SER A C 52 SER A C 1 ATOM 405 O O . SER A 1 52 ? -37.571 -12.482 -36.428 1.00 47.72 ? 52 SER A O 52 SER A O 1 ATOM 406 C CB . SER A 1 52 ? -38.525 -13.074 -33.622 1.00 47.72 ? 52 SER A CB 52 SER A CB 1 ATOM 407 O OG . SER A 1 52 ? -38.212 -14.214 -34.403 1.00 47.72 ? 52 SER A OG 52 SER A OG 1 ATOM 408 N N . VAL A 1 53 ? -37.481 -10.392 -35.856 1.00 50.98 ? 53 VAL A N 53 VAL A N 1 ATOM 409 C CA . VAL A 1 53 ? -36.411 -9.907 -36.721 1.00 50.98 ? 53 VAL A CA 53 VAL A CA 1 ATOM 410 C C . VAL A 1 53 ? -35.094 -10.581 -36.342 1.00 50.98 ? 53 VAL A C 53 VAL A C 1 ATOM 411 O O . VAL A 1 53 ? -34.312 -10.965 -37.215 1.00 50.98 ? 53 VAL A O 53 VAL A O 1 ATOM 412 C CB . VAL A 1 53 ? -36.267 -8.371 -36.639 1.00 50.98 ? 53 VAL A CB 53 VAL A CB 1 ATOM 413 C CG1 . VAL A 1 53 ? -35.063 -7.897 -37.452 1.00 50.98 ? 53 VAL A CG1 53 VAL A CG1 1 ATOM 414 C CG2 . VAL A 1 53 ? -37.545 -7.689 -37.125 1.00 50.98 ? 53 VAL A CG2 53 VAL A CG2 1 ATOM 415 N N . ALA A 1 54 ? -34.982 -11.028 -35.025 1.00 51.43 ? 54 ALA A N 54 ALA A N 1 ATOM 416 C CA . ALA A 1 54 ? -33.704 -11.601 -34.611 1.00 51.43 ? 54 ALA A CA 54 ALA A CA 1 ATOM 417 C C . ALA A 1 54 ? -33.578 -13.050 -35.072 1.00 51.43 ? 54 ALA A C 54 ALA A C 1 ATOM 418 O O . ALA A 1 54 ? -32.503 -13.483 -35.493 1.00 51.43 ? 54 ALA A O 54 ALA A O 1 ATOM 419 C CB . ALA A 1 54 ? -33.548 -11.513 -33.095 1.00 51.43 ? 54 ALA A CB 54 ALA A CB 1 ATOM 420 N N . LEU A 1 55 ? -34.814 -13.708 -35.154 1.00 50.52 ? 55 LEU A N 55 LEU A N 1 ATOM 421 C CA . LEU A 1 55 ? -34.793 -15.096 -35.601 1.00 50.52 ? 55 LEU A CA 55 LEU A CA 1 ATOM 422 C C . LEU A 1 55 ? -34.743 -15.176 -37.123 1.00 50.52 ? 55 LEU A C 55 LEU A C 1 ATOM 423 O O . LEU A 1 55 ? -34.099 -16.068 -37.681 1.00 50.52 ? 55 LEU A O 55 LEU A O 1 ATOM 424 C CB . LEU A 1 55 ? -36.022 -15.845 -35.080 1.00 50.52 ? 55 LEU A CB 55 LEU A CB 1 ATOM 425 C CG . LEU A 1 55 ? -35.925 -16.400 -33.658 1.00 50.52 ? 55 LEU A CG 55 LEU A CG 1 ATOM 426 C CD1 . LEU A 1 55 ? -37.317 -16.681 -33.102 1.00 50.52 ? 55 LEU A CD1 55 LEU A CD1 1 ATOM 427 C CD2 . LEU A 1 55 ? -35.070 -17.662 -33.633 1.00 50.52 ? 55 LEU A CD2 55 LEU A CD2 1 ATOM 428 N N . ASP A 1 56 ? -35.362 -14.202 -37.799 1.00 50.50 ? 56 ASP A N 56 ASP A N 1 ATOM 429 C CA . ASP A 1 56 ? -35.282 -14.140 -39.255 1.00 50.50 ? 56 ASP A CA 56 ASP A CA 1 ATOM 430 C C . ASP A 1 56 ? -33.868 -13.792 -39.714 1.00 50.50 ? 56 ASP A C 56 ASP A C 1 ATOM 431 O O . ASP A 1 56 ? -33.390 -14.317 -40.722 1.00 50.50 ? 56 ASP A O 56 ASP A O 1 ATOM 432 C CB . ASP A 1 56 ? -36.280 -13.118 -39.804 1.00 50.50 ? 56 ASP A CB 56 ASP A CB 1 ATOM 433 C CG . ASP A 1 56 ? -37.637 -13.723 -40.117 1.00 50.50 ? 56 ASP A CG 56 ASP A CG 1 ATOM 434 O OD1 . ASP A 1 56 ? -37.786 -14.961 -40.037 1.00 50.50 ? 56 ASP A OD1 56 ASP A OD1 1 ATOM 435 O OD2 . ASP A 1 56 ? -38.565 -12.954 -40.450 1.00 50.50 ? 56 ASP A OD2 56 ASP A OD2 1 ATOM 436 N N . LEU A 1 57 ? -33.150 -12.964 -38.900 1.00 52.32 ? 57 LEU A N 57 LEU A N 1 ATOM 437 C CA . LEU A 1 57 ? -31.760 -12.633 -39.194 1.00 52.32 ? 57 LEU A CA 57 LEU A CA 1 ATOM 438 C C . LEU A 1 57 ? -30.842 -13.809 -38.878 1.00 52.32 ? 57 LEU A C 57 LEU A C 1 ATOM 439 O O . LEU A 1 57 ? -29.863 -14.047 -39.589 1.00 52.32 ? 57 LEU A O 57 LEU A O 1 ATOM 440 C CB . LEU A 1 57 ? -31.322 -11.400 -38.398 1.00 52.32 ? 57 LEU A CB 57 LEU A CB 1 ATOM 441 C CG . LEU A 1 57 ? -31.256 -10.082 -39.172 1.00 52.32 ? 57 LEU A CG 57 LEU A CG 1 ATOM 442 C CD1 . LEU A 1 57 ? -32.032 -8.996 -38.434 1.00 52.32 ? 57 LEU A CD1 57 LEU A CD1 1 ATOM 443 C CD2 . LEU A 1 57 ? -29.807 -9.660 -39.386 1.00 52.32 ? 57 LEU A CD2 57 LEU A CD2 1 ATOM 444 N N . TYR A 1 58 ? -31.228 -14.561 -37.753 1.00 47.18 ? 58 TYR A N 58 TYR A N 1 ATOM 445 C CA . TYR A 1 58 ? -30.418 -15.682 -37.288 1.00 47.18 ? 58 TYR A CA 58 TYR A CA 1 ATOM 446 C C . TYR A 1 58 ? -30.626 -16.908 -38.169 1.00 47.18 ? 58 TYR A C 58 TYR A C 1 ATOM 447 O O . TYR A 1 58 ? -29.668 -17.608 -38.505 1.00 47.18 ? 58 TYR A O 58 TYR A O 1 ATOM 448 C CB . TYR A 1 58 ? -30.756 -16.022 -35.833 1.00 47.18 ? 58 TYR A CB 58 TYR A CB 1 ATOM 449 C CG . TYR A 1 58 ? -29.710 -16.869 -35.149 1.00 47.18 ? 58 TYR A CG 58 TYR A CG 1 ATOM 450 C CD1 . TYR A 1 58 ? -29.893 -18.241 -34.990 1.00 47.18 ? 58 TYR A CD1 58 TYR A CD1 1 ATOM 451 C CD2 . TYR A 1 58 ? -28.539 -16.301 -34.661 1.00 47.18 ? 58 TYR A CD2 58 TYR A CD2 1 ATOM 452 C CE1 . TYR A 1 58 ? -28.933 -19.026 -34.359 1.00 47.18 ? 58 TYR A CE1 58 TYR A CE1 1 ATOM 453 C CE2 . TYR A 1 58 ? -27.572 -17.075 -34.029 1.00 47.18 ? 58 TYR A CE2 58 TYR A CE2 1 ATOM 454 C CZ . TYR A 1 58 ? -27.778 -18.435 -33.883 1.00 47.18 ? 58 TYR A CZ 58 TYR A CZ 1 ATOM 455 O OH . TYR A 1 58 ? -26.824 -19.207 -33.257 1.00 47.18 ? 58 TYR A OH 58 TYR A OH 1 ATOM 456 N N . PHE A 1 59 ? -31.873 -17.065 -38.823 1.00 54.52 ? 59 PHE A N 59 PHE A N 1 ATOM 457 C CA . PHE A 1 59 ? -32.090 -18.252 -39.643 1.00 54.52 ? 59 PHE A CA 59 PHE A CA 1 ATOM 458 C C . PHE A 1 59 ? -32.267 -17.873 -41.108 1.00 54.52 ? 59 PHE A C 59 PHE A C 1 ATOM 459 O O . PHE A 1 59 ? -32.626 -18.715 -41.934 1.00 54.52 ? 59 PHE A O 59 PHE A O 1 ATOM 460 C CB . PHE A 1 59 ? -33.314 -19.030 -39.150 1.00 54.52 ? 59 PHE A CB 59 PHE A CB 1 ATOM 461 C CG . PHE A 1 59 ? -33.114 -19.694 -37.814 1.00 54.52 ? 59 PHE A CG 59 PHE A CG 1 ATOM 462 C CD1 . PHE A 1 59 ? -32.280 -20.799 -37.690 1.00 54.52 ? 59 PHE A CD1 59 PHE A CD1 1 ATOM 463 C CD2 . PHE A 1 59 ? -33.760 -19.214 -36.683 1.00 54.52 ? 59 PHE A CD2 59 PHE A CD2 1 ATOM 464 C CE1 . PHE A 1 59 ? -32.092 -21.415 -36.455 1.00 54.52 ? 59 PHE A CE1 59 PHE A CE1 1 ATOM 465 C CE2 . PHE A 1 59 ? -33.578 -19.825 -35.446 1.00 54.52 ? 59 PHE A CE2 59 PHE A CE2 1 ATOM 466 C CZ . PHE A 1 59 ? -32.744 -20.926 -35.334 1.00 54.52 ? 59 PHE A CZ 59 PHE A CZ 1 ATOM 467 N N . GLN A 1 60 ? -31.872 -16.534 -41.495 1.00 44.72 ? 60 GLN A N 60 GLN A N 1 ATOM 468 C CA . GLN A 1 60 ? -31.907 -16.175 -42.909 1.00 44.72 ? 60 GLN A CA 60 GLN A CA 1 ATOM 469 C C . GLN A 1 60 ? -32.133 -17.405 -43.783 1.00 44.72 ? 60 GLN A C 60 GLN A C 1 ATOM 470 O O . GLN A 1 60 ? -31.482 -18.435 -43.596 1.00 44.72 ? 60 GLN A O 60 GLN A O 1 ATOM 471 C CB . GLN A 1 60 ? -30.612 -15.472 -43.317 1.00 44.72 ? 60 GLN A CB 60 GLN A CB 1 ATOM 472 C CG . GLN A 1 60 ? -30.653 -13.959 -43.147 1.00 44.72 ? 60 GLN A CG 60 GLN A CG 1 ATOM 473 C CD . GLN A 1 60 ? -29.417 -13.273 -43.697 1.00 44.72 ? 60 GLN A CD 60 GLN A CD 1 ATOM 474 O OE1 . GLN A 1 60 ? -28.544 -13.917 -44.287 1.00 44.72 ? 60 GLN A OE1 60 GLN A OE1 1 ATOM 475 N NE2 . GLN A 1 60 ? -29.335 -11.960 -43.508 1.00 44.72 ? 60 GLN A NE2 60 GLN A NE2 1 ATOM 476 N N . ASN A 1 61 ? -33.437 -17.821 -44.068 1.00 42.65 ? 61 ASN A N 61 ASN A N 1 ATOM 477 C CA . ASN A 1 61 ? -33.947 -18.025 -45.420 1.00 42.65 ? 61 ASN A CA 61 ASN A CA 1 ATOM 478 C C . ASN A 1 61 ? -33.227 -19.172 -46.124 1.00 42.65 ? 61 ASN A C 61 ASN A C 1 ATOM 479 O O . ASN A 1 61 ? -32.627 -18.978 -47.182 1.00 42.65 ? 61 ASN A O 61 ASN A O 1 ATOM 480 C CB . ASN A 1 61 ? -33.823 -16.738 -46.240 1.00 42.65 ? 61 ASN A CB 61 ASN A CB 1 ATOM 481 C CG . ASN A 1 61 ? -35.077 -15.889 -46.186 1.00 42.65 ? 61 ASN A CG 61 ASN A CG 1 ATOM 482 O OD1 . ASN A 1 61 ? -36.121 -16.330 -45.698 1.00 42.65 ? 61 ASN A OD1 61 ASN A OD1 1 ATOM 483 N ND2 . ASN A 1 61 ? -34.985 -14.663 -46.688 1.00 42.65 ? 61 ASN A ND2 61 ASN A ND2 1 ATOM 484 N N . LYS A 1 62 ? -32.969 -20.338 -45.400 1.00 39.30 ? 62 LYS A N 62 LYS A N 1 ATOM 485 C CA . LYS A 1 62 ? -32.789 -21.567 -46.166 1.00 39.30 ? 62 LYS A CA 62 LYS A CA 1 ATOM 486 C C . LYS A 1 62 ? -34.132 -22.154 -46.590 1.00 39.30 ? 62 LYS A C 62 LYS A C 1 ATOM 487 O O . LYS A 1 62 ? -34.209 -23.315 -46.995 1.00 39.30 ? 62 LYS A O 62 LYS A O 1 ATOM 488 C CB . LYS A 1 62 ? -32.001 -22.596 -45.354 1.00 39.30 ? 62 LYS A CB 62 LYS A CB 1 ATOM 489 C CG . LYS A 1 62 ? -30.493 -22.510 -45.542 1.00 39.30 ? 62 LYS A CG 62 LYS A CG 1 ATOM 490 C CD . LYS A 1 62 ? -29.785 -23.713 -44.933 1.00 39.30 ? 62 LYS A CD 62 LYS A CD 1 ATOM 491 C CE . LYS A 1 62 ? -28.274 -23.616 -45.098 1.00 39.30 ? 62 LYS A CE 62 LYS A CE 1 ATOM 492 N NZ . LYS A 1 62 ? -27.572 -24.773 -44.466 1.00 39.30 ? 62 LYS A NZ 62 LYS A NZ 1 ATOM 493 N N . LYS A 1 63 ? -35.065 -21.266 -46.890 1.00 38.19 ? 63 LYS A N 63 LYS A N 1 ATOM 494 C CA . LYS A 1 63 ? -36.150 -21.980 -47.557 1.00 38.19 ? 63 LYS A CA 63 LYS A CA 1 ATOM 495 C C . LYS A 1 63 ? -36.380 -21.440 -48.965 1.00 38.19 ? 63 LYS A C 63 LYS A C 1 ATOM 496 O O . LYS A 1 63 ? -37.178 -21.993 -49.725 1.00 38.19 ? 63 LYS A O 63 LYS A O 1 ATOM 497 C CB . LYS A 1 63 ? -37.440 -21.881 -46.741 1.00 38.19 ? 63 LYS A CB 63 LYS A CB 1 ATOM 498 C CG . LYS A 1 63 ? -37.743 -23.119 -45.909 1.00 38.19 ? 63 LYS A CG 63 LYS A CG 1 ATOM 499 C CD . LYS A 1 63 ? -39.089 -23.003 -45.205 1.00 38.19 ? 63 LYS A CD 63 LYS A CD 1 ATOM 500 C CE . LYS A 1 63 ? -39.386 -24.235 -44.361 1.00 38.19 ? 63 LYS A CE 63 LYS A CE 1 ATOM 501 N NZ . LYS A 1 63 ? -40.691 -24.113 -43.644 1.00 38.19 ? 63 LYS A NZ 63 LYS A NZ 1 ATOM 502 N N . ASN A 1 64 ? -35.358 -21.096 -49.736 1.00 36.36 ? 64 ASN A N 64 ASN A N 1 ATOM 503 C CA . ASN A 1 64 ? -35.734 -21.082 -51.145 1.00 36.36 ? 64 ASN A CA 64 ASN A CA 1 ATOM 504 C C . ASN A 1 64 ? -34.587 -21.548 -52.037 1.00 36.36 ? 64 ASN A C 64 ASN A C 1 ATOM 505 O O . ASN A 1 64 ? -33.565 -20.867 -52.147 1.00 36.36 ? 64 ASN A O 64 ASN A O 1 ATOM 506 C CB . ASN A 1 64 ? -36.199 -19.685 -51.563 1.00 36.36 ? 64 ASN A CB 64 ASN A CB 1 ATOM 507 C CG . ASN A 1 64 ? -37.607 -19.374 -51.096 1.00 36.36 ? 64 ASN A CG 64 ASN A CG 1 ATOM 508 O OD1 . ASN A 1 64 ? -38.382 -20.279 -50.775 1.00 36.36 ? 64 ASN A OD1 64 ASN A OD1 1 ATOM 509 N ND2 . ASN A 1 64 ? -37.948 -18.092 -51.055 1.00 36.36 ? 64 ASN A ND2 64 ASN A ND2 1 ATOM 510 N N . GLU A 1 65 ? -34.043 -22.726 -51.821 1.00 32.72 ? 65 GLU A N 65 GLU A N 1 ATOM 511 C CA . GLU A 1 65 ? -33.544 -23.320 -53.058 1.00 32.72 ? 65 GLU A CA 65 GLU A CA 1 ATOM 512 C C . GLU A 1 65 ? -33.465 -24.840 -52.948 1.00 32.72 ? 65 GLU A C 65 GLU A C 1 ATOM 513 O O . GLU A 1 65 ? -32.641 -25.371 -52.200 1.00 32.72 ? 65 GLU A O 65 GLU A O 1 ATOM 514 C CB . GLU A 1 65 ? -32.170 -22.747 -53.415 1.00 32.72 ? 65 GLU A CB 65 GLU A CB 1 ATOM 515 C CG . GLU A 1 65 ? -32.212 -21.680 -54.500 1.00 32.72 ? 65 GLU A CG 65 GLU A CG 1 ATOM 516 C CD . GLU A 1 65 ? -30.835 -21.169 -54.892 1.00 32.72 ? 65 GLU A CD 65 GLU A CD 1 ATOM 517 O OE1 . GLU A 1 65 ? -30.742 -20.310 -55.797 1.00 32.72 ? 65 GLU A OE1 65 GLU A OE1 1 ATOM 518 O OE2 . GLU A 1 65 ? -29.841 -21.633 -54.290 1.00 32.72 ? 65 GLU A OE2 65 GLU A OE2 1 ATOM 519 N N . SER A 1 66 ? -34.552 -25.492 -52.591 1.00 33.77 ? 66 SER A N 66 SER A N 1 ATOM 520 C CA . SER A 1 66 ? -34.856 -26.833 -53.080 1.00 33.77 ? 66 SER A CA 66 SER A CA 1 ATOM 521 C C . SER A 1 66 ? -34.974 -26.853 -54.600 1.00 33.77 ? 66 SER A C 66 SER A C 1 ATOM 522 O O . SER A 1 66 ? -35.869 -26.223 -55.167 1.00 33.77 ? 66 SER A O 66 SER A O 1 ATOM 523 C CB . SER A 1 66 ? -36.150 -27.352 -52.453 1.00 33.77 ? 66 SER A CB 66 SER A CB 1 ATOM 524 O OG . SER A 1 66 ? -37.237 -26.496 -52.760 1.00 33.77 ? 66 SER A OG 66 SER A OG 1 ATOM 525 N N . GLN A 1 67 ? -33.897 -26.728 -55.394 1.00 31.82 ? 67 GLN A N 67 GLN A N 1 ATOM 526 C CA . GLN A 1 67 ? -33.792 -27.540 -56.601 1.00 31.82 ? 67 GLN A CA 67 GLN A CA 1 ATOM 527 C C . GLN A 1 67 ? -32.435 -28.234 -56.681 1.00 31.82 ? 67 GLN A C 67 GLN A C 1 ATOM 528 O O . GLN A 1 67 ? -31.400 -27.616 -56.426 1.00 31.82 ? 67 GLN A O 67 GLN A O 1 ATOM 529 C CB . GLN A 1 67 ? -34.016 -26.682 -57.847 1.00 31.82 ? 67 GLN A CB 67 GLN A CB 1 ATOM 530 C CG . GLN A 1 67 ? -35.484 -26.432 -58.165 1.00 31.82 ? 67 GLN A CG 67 GLN A CG 1 ATOM 531 C CD . GLN A 1 67 ? -35.693 -25.838 -59.546 1.00 31.82 ? 67 GLN A CD 67 GLN A CD 1 ATOM 532 O OE1 . GLN A 1 67 ? -34.732 -25.471 -60.230 1.00 31.82 ? 67 GLN A OE1 67 GLN A OE1 1 ATOM 533 N NE2 . GLN A 1 67 ? -36.950 -25.739 -59.965 1.00 31.82 ? 67 GLN A NE2 67 GLN A NE2 1 ATOM 534 N N . ASN A 1 68 ? -32.215 -29.402 -56.025 1.00 30.08 ? 68 ASN A N 68 ASN A N 1 ATOM 535 C CA . ASN A 1 68 ? -31.620 -30.658 -56.468 1.00 30.08 ? 68 ASN A CA 68 ASN A CA 1 ATOM 536 C C . ASN A 1 68 ? -30.394 -31.022 -55.636 1.00 30.08 ? 68 ASN A C 68 ASN A C 1 ATOM 537 O O . ASN A 1 68 ? -29.414 -30.275 -55.608 1.00 30.08 ? 68 ASN A O 68 ASN A O 1 ATOM 538 C CB . ASN A 1 68 ? -31.253 -30.585 -57.951 1.00 30.08 ? 68 ASN A CB 68 ASN A CB 1 ATOM 539 C CG . ASN A 1 68 ? -32.374 -31.058 -58.855 1.00 30.08 ? 68 ASN A CG 68 ASN A CG 1 ATOM 540 O OD1 . ASN A 1 68 ? -33.422 -31.506 -58.382 1.00 30.08 ? 68 ASN A OD1 68 ASN A OD1 1 ATOM 541 N ND2 . ASN A 1 68 ? -32.163 -30.961 -60.162 1.00 30.08 ? 68 ASN A ND2 68 ASN A ND2 1 ATOM 542 N N . SER A 1 69 ? -30.413 -31.673 -54.447 1.00 37.57 ? 69 SER A N 69 SER A N 1 ATOM 543 C CA . SER A 1 69 ? -29.473 -32.765 -54.218 1.00 37.57 ? 69 SER A CA 69 SER A CA 1 ATOM 544 C C . SER A 1 69 ? -29.600 -33.316 -52.801 1.00 37.57 ? 69 SER A C 69 SER A C 1 ATOM 545 O O . SER A 1 69 ? -29.816 -32.560 -51.852 1.00 37.57 ? 69 SER A O 69 SER A O 1 ATOM 546 C CB . SER A 1 69 ? -28.038 -32.298 -54.465 1.00 37.57 ? 69 SER A CB 69 SER A CB 1 ATOM 547 O OG . SER A 1 69 ? -27.674 -31.282 -53.547 1.00 37.57 ? 69 SER A OG 69 SER A OG 1 ATOM 548 N N . THR A 1 70 ? -30.388 -34.335 -52.368 1.00 31.16 ? 70 THR A N 70 THR A N 1 ATOM 549 C CA . THR A 1 70 ? -30.342 -35.639 -51.715 1.00 31.16 ? 70 THR A CA 70 THR A CA 1 ATOM 550 C C . THR A 1 70 ? -29.535 -35.568 -50.422 1.00 31.16 ? 70 THR A C 70 THR A C 1 ATOM 551 O O . THR A 1 70 ? -28.417 -35.048 -50.410 1.00 31.16 ? 70 THR A O 70 THR A O 1 ATOM 552 C CB . THR A 1 70 ? -29.738 -36.708 -52.644 1.00 31.16 ? 70 THR A CB 70 THR A CB 1 ATOM 553 O OG1 . THR A 1 70 ? -29.640 -36.179 -53.972 1.00 31.16 ? 70 THR A OG1 70 THR A OG1 1 ATOM 554 C CG2 . THR A 1 70 ? -30.601 -37.964 -52.672 1.00 31.16 ? 70 THR A CG2 70 THR A CG2 1 ATOM 555 N N . ALA A 1 71 ? -30.124 -35.556 -49.211 1.00 29.37 ? 71 ALA A N 71 ALA A N 1 ATOM 556 C CA . ALA A 1 71 ? -30.120 -36.482 -48.081 1.00 29.37 ? 71 ALA A CA 71 ALA A CA 1 ATOM 557 C C . ALA A 1 71 ? -29.482 -35.844 -46.851 1.00 29.37 ? 71 ALA A C 71 ALA A C 1 ATOM 558 O O . ALA A 1 71 ? -28.348 -35.361 -46.912 1.00 29.37 ? 71 ALA A O 71 ALA A O 1 ATOM 559 C CB . ALA A 1 71 ? -29.386 -37.769 -48.451 1.00 29.37 ? 71 ALA A CB 71 ALA A CB 1 ATOM 560 N N . VAL A 1 72 ? -30.311 -35.450 -45.818 1.00 33.33 ? 72 VAL A N 72 VAL A N 1 ATOM 561 C CA . VAL A 1 72 ? -30.400 -35.911 -44.437 1.00 33.33 ? 72 VAL A CA 72 VAL A CA 1 ATOM 562 C C . VAL A 1 72 ? -31.479 -35.123 -43.697 1.00 33.33 ? 72 VAL A C 72 VAL A C 1 ATOM 563 O O . VAL A 1 72 ? -31.442 -33.891 -43.661 1.00 33.33 ? 72 VAL A O 72 VAL A O 1 ATOM 564 C CB . VAL A 1 72 ? -29.045 -35.776 -43.705 1.00 33.33 ? 72 VAL A CB 72 VAL A CB 1 ATOM 565 C CG1 . VAL A 1 72 ? -29.182 -36.176 -42.237 1.00 33.33 ? 72 VAL A CG1 72 VAL A CG1 1 ATOM 566 C CG2 . VAL A 1 72 ? -27.979 -36.624 -44.397 1.00 33.33 ? 72 VAL A CG2 72 VAL A CG2 1 ATOM 567 N N . THR A 1 73 ? -32.765 -35.490 -43.748 1.00 28.40 ? 73 THR A N 73 THR A N 1 ATOM 568 C CA . THR A 1 73 ? -33.905 -35.769 -42.882 1.00 28.40 ? 73 THR A CA 73 THR A CA 1 ATOM 569 C C . THR A 1 73 ? -33.475 -35.814 -41.419 1.00 28.40 ? 73 THR A C 73 THR A C 1 ATOM 570 O O . THR A 1 73 ? -32.633 -36.630 -41.039 1.00 28.40 ? 73 THR A O 73 THR A O 1 ATOM 571 C CB . THR A 1 73 ? -34.584 -37.098 -43.262 1.00 28.40 ? 73 THR A CB 73 THR A CB 1 ATOM 572 O OG1 . THR A 1 73 ? -34.637 -37.210 -44.690 1.00 28.40 ? 73 THR A OG1 73 THR A OG1 1 ATOM 573 C CG2 . THR A 1 73 ? -36.002 -37.171 -42.705 1.00 28.40 ? 73 THR A CG2 73 THR A CG2 1 ATOM 574 N N . LEU A 1 74 ? -33.578 -34.783 -40.673 1.00 31.85 ? 74 LEU A N 74 LEU A N 1 ATOM 575 C CA . LEU A 1 74 ? -33.981 -34.856 -39.273 1.00 31.85 ? 74 LEU A CA 74 LEU A CA 1 ATOM 576 C C . LEU A 1 74 ? -35.380 -34.281 -39.079 1.00 31.85 ? 74 LEU A C 74 LEU A C 1 ATOM 577 O O . LEU A 1 74 ? -35.642 -33.135 -39.453 1.00 31.85 ? 74 LEU A O 74 LEU A O 1 ATOM 578 C CB . LEU A 1 74 ? -32.981 -34.107 -38.388 1.00 31.85 ? 74 LEU A CB 74 LEU A CB 1 ATOM 579 C CG . LEU A 1 74 ? -31.738 -34.889 -37.958 1.00 31.85 ? 74 LEU A CG 74 LEU A CG 1 ATOM 580 C CD1 . LEU A 1 74 ? -30.498 -34.007 -38.057 1.00 31.85 ? 74 LEU A CD1 74 LEU A CD1 1 ATOM 581 C CD2 . LEU A 1 74 ? -31.907 -35.425 -36.541 1.00 31.85 ? 74 LEU A CD2 74 LEU A CD2 1 ATOM 582 N N . GLN A 1 75 ? -36.518 -35.013 -39.196 1.00 25.92 ? 75 GLN A N 75 GLN A N 1 ATOM 583 C CA . GLN A 1 75 ? -37.745 -35.457 -38.545 1.00 25.92 ? 75 GLN A CA 75 GLN A CA 1 ATOM 584 C C . GLN A 1 75 ? -37.883 -34.845 -37.154 1.00 25.92 ? 75 GLN A C 75 GLN A C 1 ATOM 585 O O . GLN A 1 75 ? -36.935 -34.861 -36.366 1.00 25.92 ? 75 GLN A O 75 GLN A O 1 ATOM 586 C CB . GLN A 1 75 ? -37.782 -36.984 -38.452 1.00 25.92 ? 75 GLN A CB 75 GLN A CB 1 ATOM 587 C CG . GLN A 1 75 ? -38.426 -37.657 -39.657 1.00 25.92 ? 75 GLN A CG 75 GLN A CG 1 ATOM 588 C CD . GLN A 1 75 ? -38.454 -39.170 -39.538 1.00 25.92 ? 75 GLN A CD 75 GLN A CD 1 ATOM 589 O OE1 . GLN A 1 75 ? -37.934 -39.740 -38.574 1.00 25.92 ? 75 GLN A OE1 75 GLN A OE1 1 ATOM 590 N NE2 . GLN A 1 75 ? -39.059 -39.830 -40.519 1.00 25.92 ? 75 GLN A NE2 75 GLN A NE2 1 ATOM 591 N N . ASN A 1 76 ? -38.863 -33.983 -36.807 1.00 27.21 ? 76 ASN A N 76 ASN A N 1 ATOM 592 C CA . ASN A 1 76 ? -40.094 -33.958 -36.024 1.00 27.21 ? 76 ASN A CA 76 ASN A CA 1 ATOM 593 C C . ASN A 1 76 ? -39.808 -33.804 -34.533 1.00 27.21 ? 76 ASN A C 76 ASN A C 1 ATOM 594 O O . ASN A 1 76 ? -39.156 -34.658 -33.931 1.00 27.21 ? 76 ASN A O 76 ASN A O 1 ATOM 595 C CB . ASN A 1 76 ? -40.918 -35.222 -36.279 1.00 27.21 ? 76 ASN A CB 76 ASN A CB 1 ATOM 596 C CG . ASN A 1 76 ? -41.817 -35.099 -37.494 1.00 27.21 ? 76 ASN A CG 76 ASN A CG 1 ATOM 597 O OD1 . ASN A 1 76 ? -41.947 -34.021 -38.078 1.00 27.21 ? 76 ASN A OD1 76 ASN A OD1 1 ATOM 598 N ND2 . ASN A 1 76 ? -42.442 -36.204 -37.883 1.00 27.21 ? 76 ASN A ND2 76 ASN A ND2 1 ATOM 599 N N . ALA A 1 77 ? -39.941 -32.663 -33.855 1.00 28.83 ? 77 ALA A N 77 ALA A N 1 ATOM 600 C CA . ALA A 1 77 ? -40.658 -32.613 -32.583 1.00 28.83 ? 77 ALA A CA 77 ALA A CA 1 ATOM 601 C C . ALA A 1 77 ? -40.910 -31.171 -32.152 1.00 28.83 ? 77 ALA A C 77 ALA A C 1 ATOM 602 O O . ALA A 1 77 ? -40.008 -30.331 -32.214 1.00 28.83 ? 77 ALA A O 77 ALA A O 1 ATOM 603 C CB . ALA A 1 77 ? -39.878 -33.359 -31.503 1.00 28.83 ? 77 ALA A CB 77 ALA A CB 1 ATOM 604 N N . SER A 1 78 ? -42.064 -30.561 -32.484 1.00 28.52 ? 78 SER A N 78 SER A N 1 ATOM 605 C CA . SER A 1 78 ? -43.085 -29.781 -31.792 1.00 28.52 ? 78 SER A CA 78 SER A CA 1 ATOM 606 C C . SER A 1 78 ? -42.581 -29.287 -30.440 1.00 28.52 ? 78 SER A C 78 SER A C 1 ATOM 607 O O . SER A 1 78 ? -42.441 -30.072 -29.500 1.00 28.52 ? 78 SER A O 78 SER A O 1 ATOM 608 C CB . SER A 1 78 ? -44.355 -30.610 -31.600 1.00 28.52 ? 78 SER A CB 78 SER A CB 1 ATOM 609 O OG . SER A 1 78 ? -44.090 -31.764 -30.821 1.00 28.52 ? 78 SER A OG 78 SER A OG 1 ATOM 610 N N . SER A 1 79 ? -41.558 -28.375 -30.269 1.00 33.94 ? 79 SER A N 79 SER A N 1 ATOM 611 C CA . SER A 1 79 ? -41.255 -27.759 -28.982 1.00 33.94 ? 79 SER A CA 79 SER A CA 1 ATOM 612 C C . SER A 1 79 ? -41.836 -26.352 -28.891 1.00 33.94 ? 79 SER A C 79 SER A C 1 ATOM 613 O O . SER A 1 79 ? -41.840 -25.612 -29.877 1.00 33.94 ? 79 SER A O 79 SER A O 1 ATOM 614 C CB . SER A 1 79 ? -39.743 -27.710 -28.753 1.00 33.94 ? 79 SER A CB 79 SER A CB 1 ATOM 615 O OG . SER A 1 79 ? -39.117 -26.870 -29.707 1.00 33.94 ? 79 SER A OG 79 SER A OG 1 ATOM 616 N N . SER A 1 80 ? -43.133 -26.121 -28.516 1.00 33.36 ? 80 SER A N 80 SER A N 1 ATOM 617 C CA . SER A 1 80 ? -43.787 -25.084 -27.725 1.00 33.36 ? 80 SER A CA 80 SER A CA 1 ATOM 618 C C . SER A 1 80 ? -43.139 -23.722 -27.955 1.00 33.36 ? 80 SER A C 80 SER A C 1 ATOM 619 O O . SER A 1 80 ? -41.913 -23.617 -28.027 1.00 33.36 ? 80 SER A O 80 SER A O 1 ATOM 620 C CB . SER A 1 80 ? -43.740 -25.435 -26.237 1.00 33.36 ? 80 SER A CB 80 SER A CB 1 ATOM 621 O OG . SER A 1 80 ? -42.404 -25.628 -25.808 1.00 33.36 ? 80 SER A OG 80 SER A OG 1 ATOM 622 N N . PRO A 1 81 ? -43.873 -22.677 -28.494 1.00 39.40 ? 81 PRO A N 81 PRO A N 1 ATOM 623 C CA . PRO A 1 81 ? -43.473 -21.344 -28.950 1.00 39.40 ? 81 PRO A CA 81 PRO A CA 1 ATOM 624 C C . PRO A 1 81 ? -42.836 -20.508 -27.843 1.00 39.40 ? 81 PRO A C 81 PRO A C 1 ATOM 625 O O . PRO A 1 81 ? -43.336 -20.486 -26.715 1.00 39.40 ? 81 PRO A O 81 PRO A O 1 ATOM 626 C CB . PRO A 1 81 ? -44.792 -20.720 -29.414 1.00 39.40 ? 81 PRO A CB 81 PRO A CB 1 ATOM 627 C CG . PRO A 1 81 ? -45.849 -21.443 -28.642 1.00 39.40 ? 81 PRO A CG 81 PRO A CG 1 ATOM 628 C CD . PRO A 1 81 ? -45.194 -22.529 -27.839 1.00 39.40 ? 81 PRO A CD 81 PRO A CD 1 ATOM 629 N N . ALA A 1 82 ? -41.576 -20.762 -27.458 1.00 39.75 ? 82 ALA A N 82 ALA A N 1 ATOM 630 C CA . ALA A 1 82 ? -40.651 -19.972 -26.649 1.00 39.75 ? 82 ALA A CA 82 ALA A CA 1 ATOM 631 C C . ALA A 1 82 ? -40.859 -18.478 -26.878 1.00 39.75 ? 82 ALA A C 82 ALA A C 1 ATOM 632 O O . ALA A 1 82 ? -41.103 -18.045 -28.007 1.00 39.75 ? 82 ALA A O 82 ALA A O 1 ATOM 633 C CB . ALA A 1 82 ? -39.208 -20.360 -26.961 1.00 39.75 ? 82 ALA A CB 82 ALA A CB 1 ATOM 634 N N . SER A 1 83 ? -41.786 -17.797 -26.150 1.00 38.06 ? 83 SER A N 83 SER A N 1 ATOM 635 C CA . SER A 1 83 ? -41.950 -16.444 -25.628 1.00 38.06 ? 83 SER A CA 83 SER A CA 1 ATOM 636 C C . SER A 1 83 ? -40.910 -15.495 -26.214 1.00 38.06 ? 83 SER A C 83 SER A C 1 ATOM 637 O O . SER A 1 83 ? -39.709 -15.769 -26.154 1.00 38.06 ? 83 SER A O 83 SER A O 1 ATOM 638 C CB . SER A 1 83 ? -41.852 -16.441 -24.102 1.00 38.06 ? 83 SER A CB 83 SER A CB 1 ATOM 639 O OG . SER A 1 83 ? -41.591 -15.136 -23.617 1.00 38.06 ? 83 SER A OG 83 SER A OG 1 ATOM 640 N N . ILE A 1 84 ? -40.964 -15.153 -27.574 1.00 42.94 ? 84 ILE A N 84 ILE A N 1 ATOM 641 C CA . ILE A 1 84 ? -40.169 -14.299 -28.450 1.00 42.94 ? 84 ILE A CA 84 ILE A CA 1 ATOM 642 C C . ILE A 1 84 ? -40.443 -12.832 -28.129 1.00 42.94 ? 84 ILE A C 84 ILE A C 1 ATOM 643 O O . ILE A 1 84 ? -41.599 -12.428 -27.977 1.00 42.94 ? 84 ILE A O 84 ILE A O 1 ATOM 644 C CB . ILE A 1 84 ? -40.466 -14.586 -29.939 1.00 42.94 ? 84 ILE A CB 84 ILE A CB 1 ATOM 645 C CG1 . ILE A 1 84 ? -40.123 -16.040 -30.282 1.00 42.94 ? 84 ILE A CG1 84 ILE A CG1 1 ATOM 646 C CG2 . ILE A 1 84 ? -39.698 -13.615 -30.840 1.00 42.94 ? 84 ILE A CG2 84 ILE A CG2 1 ATOM 647 C CD1 . ILE A 1 84 ? -40.670 -16.506 -31.624 1.00 42.94 ? 84 ILE A CD1 84 ILE A CD1 1 ATOM 648 N N . THR A 1 85 ? -39.621 -12.194 -27.374 1.00 44.31 ? 85 THR A N 85 THR A N 1 ATOM 649 C CA . THR A 1 85 ? -39.340 -10.858 -26.860 1.00 44.31 ? 85 THR A CA 85 THR A CA 1 ATOM 650 C C . THR A 1 85 ? -39.202 -9.857 -28.004 1.00 44.31 ? 85 THR A C 85 THR A C 1 ATOM 651 O O . THR A 1 85 ? -38.714 -10.202 -29.082 1.00 44.31 ? 85 THR A O 85 THR A O 1 ATOM 652 C CB . THR A 1 85 ? -38.060 -10.845 -26.005 1.00 44.31 ? 85 THR A CB 85 THR A CB 1 ATOM 653 O OG1 . THR A 1 85 ? -37.040 -10.109 -26.692 1.00 44.31 ? 85 THR A OG1 85 THR A OG1 1 ATOM 654 C CG2 . THR A 1 85 ? -37.559 -12.262 -25.744 1.00 44.31 ? 85 THR A CG2 85 THR A CG2 1 ATOM 655 N N . THR A 1 86 ? -40.055 -8.768 -28.142 1.00 39.77 ? 86 THR A N 86 THR A N 1 ATOM 656 C CA . THR A 1 86 ? -40.233 -7.562 -28.943 1.00 39.77 ? 86 THR A CA 86 THR A CA 1 ATOM 657 C C . THR A 1 86 ? -39.127 -6.552 -28.654 1.00 39.77 ? 86 THR A C 86 THR A C 1 ATOM 658 O O . THR A 1 86 ? -39.202 -5.400 -29.087 1.00 39.77 ? 86 THR A O 86 THR A O 1 ATOM 659 C CB . THR A 1 86 ? -41.605 -6.914 -28.681 1.00 39.77 ? 86 THR A CB 86 THR A CB 1 ATOM 660 O OG1 . THR A 1 86 ? -41.819 -6.817 -27.267 1.00 39.77 ? 86 THR A OG1 86 THR A OG1 1 ATOM 661 C CG2 . THR A 1 86 ? -42.730 -7.739 -29.297 1.00 39.77 ? 86 THR A CG2 86 THR A CG2 1 ATOM 662 N N . ARG A 1 87 ? -37.981 -6.999 -28.113 1.00 50.36 ? 87 ARG A N 87 ARG A N 1 ATOM 663 C CA . ARG A 1 87 ? -37.006 -5.942 -27.867 1.00 50.36 ? 87 ARG A CA 87 ARG A CA 1 ATOM 664 C C . ARG A 1 87 ? -36.135 -5.704 -29.095 1.00 50.36 ? 87 ARG A C 87 ARG A C 1 ATOM 665 O O . ARG A 1 87 ? -35.659 -6.655 -29.719 1.00 50.36 ? 87 ARG A O 87 ARG A O 1 ATOM 666 C CB . ARG A 1 87 ? -36.129 -6.289 -26.661 1.00 50.36 ? 87 ARG A CB 87 ARG A CB 1 ATOM 667 C CG . ARG A 1 87 ? -36.740 -5.901 -25.324 1.00 50.36 ? 87 ARG A CG 87 ARG A CG 1 ATOM 668 C CD . ARG A 1 87 ? -35.722 -5.985 -24.194 1.00 50.36 ? 87 ARG A CD 87 ARG A CD 1 ATOM 669 N NE . ARG A 1 87 ? -36.229 -5.379 -22.966 1.00 50.36 ? 87 ARG A NE 87 ARG A NE 1 ATOM 670 C CZ . ARG A 1 87 ? -35.677 -5.525 -21.765 1.00 50.36 ? 87 ARG A CZ 87 ARG A CZ 1 ATOM 671 N NH1 . ARG A 1 87 ? -34.585 -6.264 -21.606 1.00 50.36 ? 87 ARG A NH1 87 ARG A NH1 1 ATOM 672 N NH2 . ARG A 1 87 ? -36.222 -4.929 -20.714 1.00 50.36 ? 87 ARG A NH2 87 ARG A NH2 1 ATOM 673 N N . THR A 1 88 ? -36.421 -4.746 -29.951 1.00 54.36 ? 88 THR A N 88 THR A N 1 ATOM 674 C CA . THR A 1 88 ? -35.621 -4.196 -31.040 1.00 54.36 ? 88 THR A CA 88 THR A CA 1 ATOM 675 C C . THR A 1 88 ? -34.246 -3.766 -30.537 1.00 54.36 ? 88 THR A C 88 THR A C 1 ATOM 676 O O . THR A 1 88 ? -34.121 -3.237 -29.430 1.00 54.36 ? 88 THR A O 88 THR A O 1 ATOM 677 C CB . THR A 1 88 ? -36.326 -2.997 -31.701 1.00 54.36 ? 88 THR A CB 88 THR A CB 1 ATOM 678 O OG1 . THR A 1 88 ? -36.840 -2.131 -30.682 1.00 54.36 ? 88 THR A OG1 88 THR A OG1 1 ATOM 679 C CG2 . THR A 1 88 ? -37.476 -3.457 -32.590 1.00 54.36 ? 88 THR A CG2 88 THR A CG2 1 ATOM 680 N N . LEU A 1 89 ? -33.237 -4.582 -30.948 1.00 57.35 ? 89 LEU A N 89 LEU A N 1 ATOM 681 C CA . LEU A 1 89 ? -31.841 -4.286 -30.645 1.00 57.35 ? 89 LEU A CA 89 LEU A CA 1 ATOM 682 C C . LEU A 1 89 ? -31.465 -2.889 -31.126 1.00 57.35 ? 89 LEU A C 89 LEU A C 1 ATOM 683 O O . LEU A 1 89 ? -32.033 -2.389 -32.099 1.00 57.35 ? 89 LEU A O 89 LEU A O 1 ATOM 684 C CB . LEU A 1 89 ? -30.920 -5.326 -31.290 1.00 57.35 ? 89 LEU A CB 89 LEU A CB 1 ATOM 685 C CG . LEU A 1 89 ? -30.974 -6.737 -30.701 1.00 57.35 ? 89 LEU A CG 89 LEU A CG 1 ATOM 686 C CD1 . LEU A 1 89 ? -30.317 -7.732 -31.652 1.00 57.35 ? 89 LEU A CD1 89 LEU A CD1 1 ATOM 687 C CD2 . LEU A 1 89 ? -30.301 -6.772 -29.333 1.00 57.35 ? 89 LEU A CD2 89 LEU A CD2 1 ATOM 688 N N . SER A 1 90 ? -31.013 -2.056 -30.275 1.00 78.33 ? 90 SER A N 90 SER A N 1 ATOM 689 C CA . SER A 1 90 ? -30.362 -0.783 -30.568 1.00 78.33 ? 90 SER A CA 90 SER A CA 1 ATOM 690 C C . SER A 1 90 ? -29.468 -0.891 -31.799 1.00 78.33 ? 90 SER A C 90 SER A C 1 ATOM 691 O O . SER A 1 90 ? -29.017 -1.983 -32.152 1.00 78.33 ? 90 SER A O 90 SER A O 1 ATOM 692 C CB . SER A 1 90 ? -29.537 -0.314 -29.369 1.00 78.33 ? 90 SER A CB 90 SER A CB 1 ATOM 693 O OG . SER A 1 90 ? -28.469 0.518 -29.788 1.00 78.33 ? 90 SER A OG 90 SER A OG 1 ATOM 694 N N . LYS A 1 91 ? -29.471 0.123 -32.652 1.00 78.15 ? 91 LYS A N 91 LYS A N 1 ATOM 695 C CA . LYS A 1 91 ? -28.655 0.262 -33.855 1.00 78.15 ? 91 LYS A CA 91 LYS A CA 1 ATOM 696 C C . LYS A 1 91 ? -27.215 -0.171 -33.595 1.00 78.15 ? 91 LYS A C 91 LYS A C 1 ATOM 697 O O . LYS A 1 91 ? -26.596 -0.822 -34.439 1.00 78.15 ? 91 LYS A O 91 LYS A O 1 ATOM 698 C CB . LYS A 1 91 ? -28.686 1.705 -34.361 1.00 78.15 ? 91 LYS A CB 91 LYS A CB 1 ATOM 699 C CG . LYS A 1 91 ? -29.913 2.044 -35.194 1.00 78.15 ? 91 LYS A CG 91 LYS A CG 1 ATOM 700 C CD . LYS A 1 91 ? -29.842 3.463 -35.742 1.00 78.15 ? 91 LYS A CD 91 LYS A CD 1 ATOM 701 C CE . LYS A 1 91 ? -31.122 3.845 -36.474 1.00 78.15 ? 91 LYS A CE 91 LYS A CE 1 ATOM 702 N NZ . LYS A 1 91 ? -31.083 5.258 -36.957 1.00 78.15 ? 91 LYS A NZ 91 LYS A NZ 1 ATOM 703 N N . LYS A 1 92 ? -26.818 0.066 -32.421 1.00 77.50 ? 92 LYS A N 92 LYS A N 1 ATOM 704 C CA . LYS A 1 92 ? -25.436 -0.280 -32.102 1.00 77.50 ? 92 LYS A CA 92 LYS A CA 1 ATOM 705 C C . LYS A 1 92 ? -25.262 -1.791 -31.981 1.00 77.50 ? 92 LYS A C 92 LYS A C 1 ATOM 706 O O . LYS A 1 92 ? -24.290 -2.352 -32.490 1.00 77.50 ? 92 LYS A O 92 LYS A O 1 ATOM 707 C CB . LYS A 1 92 ? -24.997 0.404 -30.807 1.00 77.50 ? 92 LYS A CB 92 LYS A CB 1 ATOM 708 C CG . LYS A 1 92 ? -24.621 1.869 -30.977 1.00 77.50 ? 92 LYS A CG 92 LYS A CG 1 ATOM 709 C CD . LYS A 1 92 ? -24.048 2.452 -29.692 1.00 77.50 ? 92 LYS A CD 92 LYS A CD 1 ATOM 710 C CE . LYS A 1 92 ? -23.734 3.934 -29.840 1.00 77.50 ? 92 LYS A CE 92 LYS A CE 1 ATOM 711 N NZ . LYS A 1 92 ? -23.154 4.506 -28.588 1.00 77.50 ? 92 LYS A NZ 92 LYS A NZ 1 ATOM 712 N N . ARG A 1 93 ? -26.176 -2.385 -31.355 1.00 74.63 ? 93 ARG A N 93 ARG A N 1 ATOM 713 C CA . ARG A 1 93 ? -26.136 -3.833 -31.182 1.00 74.63 ? 93 ARG A CA 93 ARG A CA 1 ATOM 714 C C . ARG A 1 93 ? -26.332 -4.549 -32.514 1.00 74.63 ? 93 ARG A C 93 ARG A C 1 ATOM 715 O O . ARG A 1 93 ? -25.669 -5.551 -32.790 1.00 74.63 ? 93 ARG A O 93 ARG A O 1 ATOM 716 C CB . ARG A 1 93 ? -27.203 -4.285 -30.183 1.00 74.63 ? 93 ARG A CB 93 ARG A CB 1 ATOM 717 C CG . ARG A 1 93 ? -26.637 -4.824 -28.879 1.00 74.63 ? 93 ARG A CG 93 ARG A CG 1 ATOM 718 C CD . ARG A 1 93 ? -27.737 -5.304 -27.942 1.00 74.63 ? 93 ARG A CD 93 ARG A CD 1 ATOM 719 N NE . ARG A 1 93 ? -27.193 -5.785 -26.674 1.00 74.63 ? 93 ARG A NE 93 ARG A NE 1 ATOM 720 C CZ . ARG A 1 93 ? -27.857 -6.539 -25.802 1.00 74.63 ? 93 ARG A CZ 93 ARG A CZ 1 ATOM 721 N NH1 . ARG A 1 93 ? -29.108 -6.915 -26.045 1.00 74.63 ? 93 ARG A NH1 93 ARG A NH1 1 ATOM 722 N NH2 . ARG A 1 93 ? -27.266 -6.920 -24.679 1.00 74.63 ? 93 ARG A NH2 93 ARG A NH2 1 ATOM 723 N N . ALA A 1 94 ? -27.170 -4.008 -33.368 1.00 78.42 ? 94 ALA A N 94 ALA A N 1 ATOM 724 C CA . ALA A 1 94 ? -27.413 -4.558 -34.699 1.00 78.42 ? 94 ALA A CA 94 ALA A CA 1 ATOM 725 C C . ALA A 1 94 ? -26.161 -4.470 -35.567 1.00 78.42 ? 94 ALA A C 94 ALA A C 1 ATOM 726 O O . ALA A 1 94 ? -25.833 -5.411 -36.293 1.00 78.42 ? 94 ALA A O 94 ALA A O 1 ATOM 727 C CB . ALA A 1 94 ? -28.575 -3.831 -35.372 1.00 78.42 ? 94 ALA A CB 94 ALA A CB 1 ATOM 728 N N . LYS A 1 95 ? -25.470 -3.281 -35.455 1.00 85.24 ? 95 LYS A N 95 LYS A N 1 ATOM 729 C CA . LYS A 1 95 ? -24.225 -3.109 -36.198 1.00 85.24 ? 95 LYS A CA 95 LYS A CA 1 ATOM 730 C C . LYS A 1 95 ? -23.151 -4.073 -35.703 1.00 85.24 ? 95 LYS A C 95 LYS A C 1 ATOM 731 O O . LYS A 1 95 ? -22.392 -4.628 -36.500 1.00 85.24 ? 95 LYS A O 95 LYS A O 1 ATOM 732 C CB . LYS A 1 95 ? -23.727 -1.667 -36.086 1.00 85.24 ? 95 LYS A CB 95 LYS A CB 1 ATOM 733 C CG . LYS A 1 95 ? -24.286 -0.734 -37.150 1.00 85.24 ? 95 LYS A CG 95 LYS A CG 1 ATOM 734 C CD . LYS A 1 95 ? -23.686 0.662 -37.041 1.00 85.24 ? 95 LYS A CD 95 LYS A CD 1 ATOM 735 C CE . LYS A 1 95 ? -24.354 1.635 -38.003 1.00 85.24 ? 95 LYS A CE 95 LYS A CE 1 ATOM 736 N NZ . LYS A 1 95 ? -23.765 3.004 -37.903 1.00 85.24 ? 95 LYS A NZ 95 LYS A NZ 1 ATOM 737 N N . LYS A 1 96 ? -23.115 -4.324 -34.389 1.00 86.41 ? 96 LYS A N 96 LYS A N 1 ATOM 738 C CA . LYS A 1 96 ? -22.180 -5.283 -33.807 1.00 86.41 ? 96 LYS A CA 96 LYS A CA 1 ATOM 739 C C . LYS A 1 96 ? -22.459 -6.697 -34.309 1.00 86.41 ? 96 LYS A C 96 LYS A C 1 ATOM 740 O O . LYS A 1 96 ? -21.532 -7.430 -34.661 1.00 86.41 ? 96 LYS A O 96 LYS A O 1 ATOM 741 C CB . LYS A 1 96 ? -22.253 -5.245 -32.280 1.00 86.41 ? 96 LYS A CB 96 LYS A CB 1 ATOM 742 C CG . LYS A 1 96 ? -21.138 -6.015 -31.588 1.00 86.41 ? 96 LYS A CG 96 LYS A CG 1 ATOM 743 C CD . LYS A 1 96 ? -21.184 -5.827 -30.077 1.00 86.41 ? 96 LYS A CD 96 LYS A CD 1 ATOM 744 C CE . LYS A 1 96 ? -20.050 -6.572 -29.386 1.00 86.41 ? 96 LYS A CE 96 LYS A CE 1 ATOM 745 N NZ . LYS A 1 96 ? -20.147 -6.472 -27.899 1.00 86.41 ? 96 LYS A NZ 96 LYS A NZ 1 ATOM 746 N N . ILE A 1 97 ? -23.680 -7.064 -34.351 1.00 79.67 ? 97 ILE A N 97 ILE A N 1 ATOM 747 C CA . ILE A 1 97 ? -24.077 -8.390 -34.812 1.00 79.67 ? 97 ILE A CA 97 ILE A CA 1 ATOM 748 C C . ILE A 1 97 ? -23.737 -8.545 -36.293 1.00 79.67 ? 97 ILE A C 97 ILE A C 1 ATOM 749 O O . ILE A 1 97 ? -23.248 -9.595 -36.717 1.00 79.67 ? 97 ILE A O 97 ILE A O 1 ATOM 750 C CB . ILE A 1 97 ? -25.584 -8.642 -34.579 1.00 79.67 ? 97 ILE A CB 97 ILE A CB 1 ATOM 751 C CG1 . ILE A 1 97 ? -25.887 -8.718 -33.079 1.00 79.67 ? 97 ILE A CG1 97 ILE A CG1 1 ATOM 752 C CG2 . ILE A 1 97 ? -26.035 -9.919 -35.295 1.00 79.67 ? 97 ILE A CG2 97 ILE A CG2 1 ATOM 753 C CD1 . ILE A 1 97 ? -27.372 -8.771 -32.749 1.00 79.67 ? 97 ILE A CD1 97 ILE A CD1 1 ATOM 754 N N . GLU A 1 98 ? -23.961 -7.475 -37.051 1.00 83.89 ? 98 GLU A N 98 GLU A N 1 ATOM 755 C CA . GLU A 1 98 ? -23.617 -7.491 -38.470 1.00 83.89 ? 98 GLU A CA 98 GLU A CA 1 ATOM 756 C C . GLU A 1 98 ? -22.111 -7.630 -38.671 1.00 83.89 ? 98 GLU A C 98 GLU A C 1 ATOM 757 O O . GLU A 1 98 ? -21.663 -8.380 -39.541 1.00 83.89 ? 98 GLU A O 98 GLU A O 1 ATOM 758 C CB . GLU A 1 98 ? -24.126 -6.223 -39.161 1.00 83.89 ? 98 GLU A CB 98 GLU A CB 1 ATOM 759 C CG . GLU A 1 98 ? -24.155 -6.320 -40.679 1.00 83.89 ? 98 GLU A CG 98 GLU A CG 1 ATOM 760 C CD . GLU A 1 98 ? -24.681 -5.062 -41.351 1.00 83.89 ? 98 GLU A CD 98 GLU A CD 1 ATOM 761 O OE1 . GLU A 1 98 ? -24.678 -4.994 -42.601 1.00 83.89 ? 98 GLU A OE1 98 GLU A OE1 1 ATOM 762 O OE2 . GLU A 1 98 ? -25.099 -4.135 -40.621 1.00 83.89 ? 98 GLU A OE2 98 GLU A OE2 1 ATOM 763 N N . ARG A 1 99 ? -21.359 -6.897 -37.872 1.00 88.06 ? 99 ARG A N 99 ARG A N 1 ATOM 764 C CA . ARG A 1 99 ? -19.905 -7.006 -37.949 1.00 88.06 ? 99 ARG A CA 99 ARG A CA 1 ATOM 765 C C . ARG A 1 99 ? -19.442 -8.415 -37.593 1.00 88.06 ? 99 ARG A C 99 ARG A C 1 ATOM 766 O O . ARG A 1 99 ? -18.562 -8.969 -38.255 1.00 88.06 ? 99 ARG A O 99 ARG A O 1 ATOM 767 C CB . ARG A 1 99 ? -19.240 -5.986 -37.022 1.00 88.06 ? 99 ARG A CB 99 ARG A CB 1 ATOM 768 C CG . ARG A 1 99 ? -18.836 -4.695 -37.716 1.00 88.06 ? 99 ARG A CG 99 ARG A CG 1 ATOM 769 C CD . ARG A 1 99 ? -18.027 -3.790 -36.797 1.00 88.06 ? 99 ARG A CD 99 ARG A CD 1 ATOM 770 N NE . ARG A 1 99 ? -18.873 -3.140 -35.800 1.00 88.06 ? 99 ARG A NE 99 ARG A NE 1 ATOM 771 C CZ . ARG A 1 99 ? -18.422 -2.417 -34.778 1.00 88.06 ? 99 ARG A CZ 99 ARG A CZ 1 ATOM 772 N NH1 . ARG A 1 99 ? -17.119 -2.238 -34.597 1.00 88.06 ? 99 ARG A NH1 99 ARG A NH1 1 ATOM 773 N NH2 . ARG A 1 99 ? -19.281 -1.870 -33.930 1.00 88.06 ? 99 ARG A NH2 99 ARG A NH2 1 ATOM 774 N N . ASN A 1 100 ? -20.003 -9.029 -36.524 1.00 84.65 ? 100 ASN A N 100 ASN A N 1 ATOM 775 C CA . ASN A 1 100 ? -19.656 -10.382 -36.103 1.00 84.65 ? 100 ASN A CA 100 ASN A CA 1 ATOM 776 C C . ASN A 1 100 ? -20.013 -11.411 -37.171 1.00 84.65 ? 100 ASN A C 100 ASN A C 1 ATOM 777 O O . ASN A 1 100 ? -19.272 -12.371 -37.386 1.00 84.65 ? 100 ASN A O 100 ASN A O 1 ATOM 778 C CB . ASN A 1 100 ? -20.347 -10.726 -34.782 1.00 84.65 ? 100 ASN A CB 100 ASN A CB 1 ATOM 779 C CG . ASN A 1 100 ? -19.620 -10.161 -33.577 1.00 84.65 ? 100 ASN A CG 100 ASN A CG 1 ATOM 780 O OD1 . ASN A 1 100 ? -18.406 -9.947 -33.614 1.00 84.65 ? 100 ASN A OD1 100 ASN A OD1 1 ATOM 781 N ND2 . ASN A 1 100 ? -20.358 -9.914 -32.501 1.00 84.65 ? 100 ASN A ND2 100 ASN A ND2 1 ATOM 782 N N . LEU A 1 101 ? -21.067 -11.207 -37.868 1.00 81.15 ? 101 LEU A N 101 LEU A N 1 ATOM 783 C CA . LEU A 1 101 ? -21.476 -12.088 -38.956 1.00 81.15 ? 101 LEU A CA 101 LEU A CA 1 ATOM 784 C C . LEU A 1 101 ? -20.497 -12.002 -40.123 1.00 81.15 ? 101 LEU A C 101 LEU A C 1 ATOM 785 O O . LEU A 1 101 ? -20.176 -13.017 -40.745 1.00 81.15 ? 101 LEU A O 101 LEU A O 1 ATOM 786 C CB . LEU A 1 101 ? -22.887 -11.733 -39.432 1.00 81.15 ? 101 LEU A CB 101 LEU A CB 1 ATOM 787 C CG . LEU A 1 101 ? -24.036 -12.507 -38.784 1.00 81.15 ? 101 LEU A CG 101 LEU A CG 1 ATOM 788 C CD1 . LEU A 1 101 ? -25.362 -11.797 -39.035 1.00 81.15 ? 101 LEU A CD1 101 LEU A CD1 1 ATOM 789 C CD2 . LEU A 1 101 ? -24.081 -13.938 -39.310 1.00 81.15 ? 101 LEU A CD2 101 LEU A CD2 1 ATOM 790 N N . LYS A 1 102 ? -20.073 -10.789 -40.365 1.00 84.76 ? 102 LYS A N 102 LYS A N 1 ATOM 791 C CA . LYS A 1 102 ? -19.073 -10.616 -41.415 1.00 84.76 ? 102 LYS A CA 102 LYS A CA 1 ATOM 792 C C . LYS A 1 102 ? -17.783 -11.355 -41.073 1.00 84.76 ? 102 LYS A C 102 LYS A C 1 ATOM 793 O O . LYS A 1 102 ? -17.178 -11.991 -41.938 1.00 84.76 ? 102 LYS A O 102 LYS A O 1 ATOM 794 C CB . LYS A 1 102 ? -18.782 -9.131 -41.640 1.00 84.76 ? 102 LYS A CB 102 LYS A CB 1 ATOM 795 C CG . LYS A 1 102 ? -19.772 -8.440 -42.566 1.00 84.76 ? 102 LYS A CG 102 LYS A CG 1 ATOM 796 C CD . LYS A 1 102 ? -19.341 -7.013 -42.880 1.00 84.76 ? 102 LYS A CD 102 LYS A CD 1 ATOM 797 C CE . LYS A 1 102 ? -20.379 -6.287 -43.725 1.00 84.76 ? 102 LYS A CE 102 LYS A CE 1 ATOM 798 N NZ . LYS A 1 102 ? -19.973 -4.879 -44.013 1.00 84.76 ? 102 LYS A NZ 102 LYS A NZ 1 ATOM 799 N N . TYR A 1 103 ? -17.399 -11.337 -39.782 1.00 84.42 ? 103 TYR A N 103 TYR A N 1 ATOM 800 C CA . TYR A 1 103 ? -16.193 -12.018 -39.323 1.00 84.42 ? 103 TYR A CA 103 TYR A CA 1 ATOM 801 C C . TYR A 1 103 ? -16.358 -13.531 -39.399 1.00 84.42 ? 103 TYR A C 103 TYR A C 1 ATOM 802 O O . TYR A 1 103 ? -15.430 -14.244 -39.789 1.00 84.42 ? 103 TYR A O 103 TYR A O 1 ATOM 803 C CB . TYR A 1 103 ? -15.854 -11.601 -37.888 1.00 84.42 ? 103 TYR A CB 103 TYR A CB 1 ATOM 804 C CG . TYR A 1 103 ? -15.312 -10.197 -37.776 1.00 84.42 ? 103 TYR A CG 103 TYR A CG 1 ATOM 805 C CD1 . TYR A 1 103 ? -14.346 -9.730 -38.664 1.00 84.42 ? 103 TYR A CD1 103 TYR A CD1 1 ATOM 806 C CD2 . TYR A 1 103 ? -15.762 -9.336 -36.781 1.00 84.42 ? 103 TYR A CD2 103 TYR A CD2 1 ATOM 807 C CE1 . TYR A 1 103 ? -13.842 -8.437 -38.563 1.00 84.42 ? 103 TYR A CE1 103 TYR A CE1 1 ATOM 808 C CE2 . TYR A 1 103 ? -15.265 -8.042 -36.670 1.00 84.42 ? 103 TYR A CE2 103 TYR A CE2 1 ATOM 809 C CZ . TYR A 1 103 ? -14.307 -7.602 -37.565 1.00 84.42 ? 103 TYR A CZ 103 TYR A CZ 1 ATOM 810 O OH . TYR A 1 103 ? -13.811 -6.322 -37.461 1.00 84.42 ? 103 TYR A OH 103 TYR A OH 1 ATOM 811 N N . ALA A 1 104 ? -17.469 -13.958 -39.035 1.00 80.30 ? 104 ALA A N 104 ALA A N 1 ATOM 812 C CA . ALA A 1 104 ? -17.763 -15.388 -39.084 1.00 80.30 ? 104 ALA A CA 104 ALA A CA 1 ATOM 813 C C . ALA A 1 104 ? -17.760 -15.900 -40.522 1.00 80.30 ? 104 ALA A C 104 ALA A C 1 ATOM 814 O O . ALA A 1 104 ? -17.255 -16.991 -40.798 1.00 80.30 ? 104 ALA A O 104 ALA A O 1 ATOM 815 C CB . ALA A 1 104 ? -19.108 -15.678 -38.422 1.00 80.30 ? 104 ALA A CB 104 ALA A CB 1 ATOM 816 N N . THR A 1 105 ? -18.350 -15.151 -41.435 1.00 79.05 ? 105 THR A N 105 THR A N 1 ATOM 817 C CA . THR A 1 105 ? -18.344 -15.516 -42.847 1.00 79.05 ? 105 THR A CA 105 THR A CA 1 ATOM 818 C C . THR A 1 105 ? -16.921 -15.530 -43.397 1.00 79.05 ? 105 THR A C 105 THR A C 1 ATOM 819 O O . THR A 1 105 ? -16.565 -16.403 -44.191 1.00 79.05 ? 105 THR A O 105 THR A O 1 ATOM 820 C CB . THR A 1 105 ? -19.209 -14.549 -43.677 1.00 79.05 ? 105 THR A CB 105 THR A CB 1 ATOM 821 O OG1 . THR A 1 105 ? -18.780 -13.204 -43.433 1.00 79.05 ? 105 THR A OG1 105 THR A OG1 1 ATOM 822 C CG2 . THR A 1 105 ? -20.683 -14.675 -43.309 1.00 79.05 ? 105 THR A CG2 105 THR A CG2 1 ATOM 823 N N . GLN A 1 106 ? -16.113 -14.571 -43.028 1.00 77.56 ? 106 GLN A N 106 GLN A N 1 ATOM 824 C CA . GLN A 1 106 ? -14.724 -14.529 -43.474 1.00 77.56 ? 106 GLN A CA 106 GLN A CA 1 ATOM 825 C C . GLN A 1 106 ? -13.942 -15.731 -42.952 1.00 77.56 ? 106 GLN A C 106 GLN A C 1 ATOM 826 O O . GLN A 1 106 ? -13.106 -16.291 -43.664 1.00 77.56 ? 106 GLN A O 106 GLN A O 1 ATOM 827 C CB . GLN A 1 106 ? -14.054 -13.230 -43.022 1.00 77.56 ? 106 GLN A CB 106 GLN A CB 1 ATOM 828 C CG . GLN A 1 106 ? -14.452 -12.014 -43.847 1.00 77.56 ? 106 GLN A CG 106 GLN A CG 1 ATOM 829 C CD . GLN A 1 106 ? -13.777 -10.739 -43.377 1.00 77.56 ? 106 GLN A CD 106 GLN A CD 1 ATOM 830 O OE1 . GLN A 1 106 ? -13.038 -10.741 -42.387 1.00 77.56 ? 106 GLN A OE1 106 GLN A OE1 1 ATOM 831 N NE2 . GLN A 1 106 ? -14.027 -9.641 -44.081 1.00 77.56 ? 106 GLN A NE2 106 GLN A NE2 1 ATOM 832 N N . ARG A 1 107 ? -14.158 -16.101 -41.732 1.00 77.94 ? 107 ARG A N 107 ARG A N 1 ATOM 833 C CA . ARG A 1 107 ? -13.520 -17.278 -41.151 1.00 77.94 ? 107 ARG A CA 107 ARG A CA 1 ATOM 834 C C . ARG A 1 107 ? -13.948 -18.548 -41.878 1.00 77.94 ? 107 ARG A C 107 ARG A C 1 ATOM 835 O O . ARG A 1 107 ? -13.132 -19.442 -42.110 1.00 77.94 ? 107 ARG A O 107 ARG A O 1 ATOM 836 C CB . ARG A 1 107 ? -13.852 -17.389 -39.662 1.00 77.94 ? 107 ARG A CB 107 ARG A CB 1 ATOM 837 C CG . ARG A 1 107 ? -12.817 -18.159 -38.856 1.00 77.94 ? 107 ARG A CG 107 ARG A CG 1 ATOM 838 C CD . ARG A 1 107 ? -13.108 -18.102 -37.363 1.00 77.94 ? 107 ARG A CD 107 ARG A CD 1 ATOM 839 N NE . ARG A 1 107 ? -12.127 -18.862 -36.593 1.00 77.94 ? 107 ARG A NE 107 ARG A NE 1 ATOM 840 C CZ . ARG A 1 107 ? -12.139 -18.994 -35.270 1.00 77.94 ? 107 ARG A CZ 107 ARG A CZ 1 ATOM 841 N NH1 . ARG A 1 107 ? -13.087 -18.416 -34.540 1.00 77.94 ? 107 ARG A NH1 107 ARG A NH1 1 ATOM 842 N NH2 . ARG A 1 107 ? -11.198 -19.709 -34.671 1.00 77.94 ? 107 ARG A NH2 107 ARG A NH2 1 ATOM 843 N N . LYS A 1 108 ? -15.218 -18.665 -42.163 1.00 77.76 ? 108 LYS A N 108 LYS A N 1 ATOM 844 C CA . LYS A 1 108 ? -15.723 -19.815 -42.906 1.00 77.76 ? 108 LYS A CA 108 LYS A CA 1 ATOM 845 C C . LYS A 1 108 ? -15.133 -19.865 -44.312 1.00 77.76 ? 108 LYS A C 108 LYS A C 1 ATOM 846 O O . LYS A 1 108 ? -14.802 -20.941 -44.815 1.00 77.76 ? 108 LYS A O 108 LYS A O 1 ATOM 847 C CB . LYS A 1 108 ? -17.251 -19.778 -42.980 1.00 77.76 ? 108 LYS A CB 108 LYS A CB 1 ATOM 848 C CG . LYS A 1 108 ? -17.893 -21.138 -43.208 1.00 77.76 ? 108 LYS A CG 108 LYS A CG 1 ATOM 849 C CD . LYS A 1 108 ? -19.414 -21.045 -43.205 1.00 77.76 ? 108 LYS A CD 108 LYS A CD 1 ATOM 850 C CE . LYS A 1 108 ? -20.056 -22.377 -43.570 1.00 77.76 ? 108 LYS A CE 108 LYS A CE 1 ATOM 851 N NZ . LYS A 1 108 ? -21.547 -22.289 -43.577 1.00 77.76 ? 108 LYS A NZ 108 LYS A NZ 1 ATOM 852 N N . LEU A 1 109 ? -15.029 -18.697 -44.990 1.00 75.59 ? 109 LEU A N 109 LEU A N 1 ATOM 853 C CA . LEU A 1 109 ? -14.410 -18.638 -46.310 1.00 75.59 ? 109 LEU A CA 109 LEU A CA 1 ATOM 854 C C . LEU A 1 109 ? -12.949 -19.072 -46.245 1.00 75.59 ? 109 LEU A C 109 LEU A C 1 ATOM 855 O O . LEU A 1 109 ? -12.468 -19.780 -47.133 1.00 75.59 ? 109 LEU A O 109 LEU A O 1 ATOM 856 C CB . LEU A 1 109 ? -14.509 -17.224 -46.887 1.00 75.59 ? 109 LEU A CB 109 LEU A CB 1 ATOM 857 C CG . LEU A 1 109 ? -15.100 -17.104 -48.292 1.00 75.59 ? 109 LEU A CG 109 LEU A CG 1 ATOM 858 C CD1 . LEU A 1 109 ? -15.873 -15.797 -48.433 1.00 75.59 ? 109 LEU A CD1 109 LEU A CD1 1 ATOM 859 C CD2 . LEU A 1 109 ? -14.001 -17.197 -49.345 1.00 75.59 ? 109 LEU A CD2 109 LEU A CD2 1 ATOM 860 N N . LEU A 1 110 ? -12.234 -18.713 -45.184 1.00 72.08 ? 110 LEU A N 110 LEU A N 1 ATOM 861 C CA . LEU A 1 110 ? -10.839 -19.110 -45.026 1.00 72.08 ? 110 LEU A CA 110 LEU A CA 1 ATOM 862 C C . LEU A 1 110 ? -10.727 -20.609 -44.769 1.00 72.08 ? 110 LEU A C 110 LEU A C 1 ATOM 863 O O . LEU A 1 110 ? -9.824 -21.267 -45.292 1.00 72.08 ? 110 LEU A O 110 LEU A O 1 ATOM 864 C CB . LEU A 1 110 ? -10.187 -18.333 -43.879 1.00 72.08 ? 110 LEU A CB 110 LEU A CB 1 ATOM 865 C CG . LEU A 1 110 ? -9.674 -16.932 -44.214 1.00 72.08 ? 110 LEU A CG 110 LEU A CG 1 ATOM 866 C CD1 . LEU A 1 110 ? -9.415 -16.142 -42.936 1.00 72.08 ? 110 LEU A CD1 110 LEU A CD1 1 ATOM 867 C CD2 . LEU A 1 110 ? -8.410 -17.014 -45.063 1.00 72.08 ? 110 LEU A CD2 110 LEU A CD2 1 ATOM 868 N N . VAL A 1 111 ? -11.707 -21.113 -44.047 1.00 75.61 ? 111 VAL A N 111 VAL A N 1 ATOM 869 C CA . VAL A 1 111 ? -11.742 -22.546 -43.778 1.00 75.61 ? 111 VAL A CA 111 VAL A CA 1 ATOM 870 C C . VAL A 1 111 ? -12.089 -23.305 -45.056 1.00 75.61 ? 111 VAL A C 111 VAL A C 1 ATOM 871 O O . VAL A 1 111 ? -11.475 -24.329 -45.364 1.00 75.61 ? 111 VAL A O 111 VAL A O 1 ATOM 872 C CB . VAL A 1 111 ? -12.754 -22.890 -42.662 1.00 75.61 ? 111 VAL A CB 111 VAL A CB 1 ATOM 873 C CG1 . VAL A 1 111 ? -12.934 -24.402 -42.544 1.00 75.61 ? 111 VAL A CG1 111 VAL A CG1 1 ATOM 874 C CG2 . VAL A 1 111 ? -12.301 -22.296 -41.330 1.00 75.61 ? 111 VAL A CG2 111 VAL A CG2 1 ATOM 875 N N . ASP A 1 112 ? -13.047 -22.779 -45.788 1.00 72.19 ? 112 ASP A N 112 ASP A N 1 ATOM 876 C CA . ASP A 1 112 ? -13.439 -23.416 -47.042 1.00 72.19 ? 112 ASP A CA 112 ASP A CA 1 ATOM 877 C C . ASP A 1 112 ? -12.325 -23.314 -48.081 1.00 72.19 ? 112 ASP A C 112 ASP A C 1 ATOM 878 O O . ASP A 1 112 ? -12.106 -24.245 -48.859 1.00 72.19 ? 112 ASP A O 112 ASP A O 1 ATOM 879 C CB . ASP A 1 112 ? -14.724 -22.787 -47.584 1.00 72.19 ? 112 ASP A CB 112 ASP A CB 1 ATOM 880 C CG . ASP A 1 112 ? -15.963 -23.219 -46.821 1.00 72.19 ? 112 ASP A CG 112 ASP A CG 1 ATOM 881 O OD1 . ASP A 1 112 ? -15.892 -24.197 -46.046 1.00 72.19 ? 112 ASP A OD1 112 ASP A OD1 1 ATOM 882 O OD2 . ASP A 1 112 ? -17.021 -22.578 -46.999 1.00 72.19 ? 112 ASP A OD2 112 ASP A OD2 1 ATOM 883 N N . ALA A 1 113 ? -11.634 -22.116 -48.128 1.00 66.40 ? 113 ALA A N 113 ALA A N 1 ATOM 884 C CA . ALA A 1 113 ? -10.501 -21.951 -49.035 1.00 66.40 ? 113 ALA A CA 113 ALA A CA 1 ATOM 885 C C . ALA A 1 113 ? -9.375 -22.920 -48.687 1.00 66.40 ? 113 ALA A C 113 ALA A C 1 ATOM 886 O O . ALA A 1 113 ? -8.723 -23.470 -49.578 1.00 66.40 ? 113 ALA A O 113 ALA A O 1 ATOM 887 C CB . ALA A 1 113 ? -9.992 -20.512 -48.994 1.00 66.40 ? 113 ALA A CB 113 ALA A CB 1 ATOM 888 N N . SER A 1 114 ? -9.199 -23.167 -47.404 1.00 62.47 ? 114 SER A N 114 SER A N 1 ATOM 889 C CA . SER A 1 114 ? -8.179 -24.119 -46.978 1.00 62.47 ? 114 SER A CA 114 SER A CA 1 ATOM 890 C C . SER A 1 114 ? -8.607 -25.554 -47.268 1.00 62.47 ? 114 SER A C 114 SER A C 1 ATOM 891 O O . SER A 1 114 ? -7.778 -26.395 -47.621 1.00 62.47 ? 114 SER A O 114 SER A O 1 ATOM 892 C CB . SER A 1 114 ? -7.883 -23.958 -45.487 1.00 62.47 ? 114 SER A CB 114 SER A CB 1 ATOM 893 O OG . SER A 1 114 ? -9.050 -24.187 -44.715 1.00 62.47 ? 114 SER A OG 114 SER A OG 1 ATOM 894 N N . ALA A 1 115 ? -9.892 -25.801 -47.121 1.00 66.63 ? 115 ALA A N 115 ALA A N 1 ATOM 895 C CA . ALA A 1 115 ? -10.431 -27.122 -47.435 1.00 66.63 ? 115 ALA A CA 115 ALA A CA 1 ATOM 896 C C . ALA A 1 115 ? -10.393 -27.387 -48.937 1.00 66.63 ? 115 ALA A C 115 ALA A C 1 ATOM 897 O O . ALA A 1 115 ? -10.134 -28.513 -49.368 1.00 66.63 ? 115 ALA A O 115 ALA A O 1 ATOM 898 C CB . ALA A 1 115 ? -11.859 -27.252 -46.910 1.00 66.63 ? 115 ALA A CB 115 ALA A CB 1 ATOM 899 N N . LYS A 1 116 ? -10.618 -26.333 -49.810 1.00 58.39 ? 116 LYS A N 116 LYS A N 1 ATOM 900 C CA . LYS A 1 116 ? -10.568 -26.481 -51.262 1.00 58.39 ? 116 LYS A CA 116 LYS A CA 1 ATOM 901 C C . LYS A 1 116 ? -9.132 -26.660 -51.746 1.00 58.39 ? 116 LYS A C 116 LYS A C 1 ATOM 902 O O . LYS A 1 116 ? -8.884 -27.377 -52.718 1.00 58.39 ? 116 LYS A O 116 LYS A O 1 ATOM 903 C CB . LYS A 1 116 ? -11.205 -25.271 -51.948 1.00 58.39 ? 116 LYS A CB 116 LYS A CB 1 ATOM 904 C CG . LYS A 1 116 ? -12.726 -25.269 -51.910 1.00 58.39 ? 116 LYS A CG 116 LYS A CG 1 ATOM 905 C CD . LYS A 1 116 ? -13.303 -24.124 -52.732 1.00 58.39 ? 116 LYS A CD 116 LYS A CD 1 ATOM 906 C CE . LYS A 1 116 ? -14.823 -24.086 -52.650 1.00 58.39 ? 116 LYS A CE 116 LYS A CE 1 ATOM 907 N NZ . LYS A 1 116 ? -15.396 -22.988 -53.485 1.00 58.39 ? 116 LYS A NZ 116 LYS A NZ 1 ATOM 908 N N . LEU A 1 117 ? -8.137 -26.094 -51.031 1.00 54.94 ? 117 LEU A N 117 LEU A N 1 ATOM 909 C CA . LEU A 1 117 ? -6.730 -26.273 -51.370 1.00 54.94 ? 117 LEU A CA 117 LEU A CA 1 ATOM 910 C C . LEU A 1 117 ? -6.270 -27.692 -51.049 1.00 54.94 ? 117 LEU A C 117 LEU A C 1 ATOM 911 O O . LEU A 1 117 ? -5.441 -28.257 -51.765 1.00 54.94 ? 117 LEU A O 117 LEU A O 1 ATOM 912 C CB . LEU A 1 117 ? -5.864 -25.261 -50.616 1.00 54.94 ? 117 LEU A CB 117 LEU A CB 1 ATOM 913 C CG . LEU A 1 117 ? -5.262 -24.129 -51.450 1.00 54.94 ? 117 LEU A CG 117 LEU A CG 1 ATOM 914 C CD1 . LEU A 1 117 ? -5.355 -22.807 -50.696 1.00 54.94 ? 117 LEU A CD1 117 LEU A CD1 1 ATOM 915 C CD2 . LEU A 1 117 ? -3.814 -24.443 -51.813 1.00 54.94 ? 117 LEU A CD2 117 LEU A CD2 1 ATOM 916 N N . GLU A 1 118 ? -6.975 -28.370 -50.209 1.00 53.66 ? 118 GLU A N 118 GLU A N 1 ATOM 917 C CA . GLU A 1 118 ? -6.618 -29.727 -49.807 1.00 53.66 ? 118 GLU A CA 118 GLU A CA 1 ATOM 918 C C . GLU A 1 118 ? -7.275 -30.762 -50.716 1.00 53.66 ? 118 GLU A C 118 GLU A C 1 ATOM 919 O O . GLU A 1 118 ? -6.704 -31.826 -50.967 1.00 53.66 ? 118 GLU A O 118 GLU A O 1 ATOM 920 C CB . GLU A 1 118 ? -7.015 -29.979 -48.350 1.00 53.66 ? 118 GLU A CB 118 GLU A CB 1 ATOM 921 C CG . GLU A 1 118 ? -6.080 -29.333 -47.338 1.00 53.66 ? 118 GLU A CG 118 GLU A CG 1 ATOM 922 C CD . GLU A 1 118 ? -6.279 -29.850 -45.922 1.00 53.66 ? 118 GLU A CD 118 GLU A CD 1 ATOM 923 O OE1 . GLU A 1 118 ? -5.472 -29.503 -45.030 1.00 53.66 ? 118 GLU A OE1 118 GLU A OE1 1 ATOM 924 O OE2 . GLU A 1 118 ? -7.250 -30.608 -45.703 1.00 53.66 ? 118 GLU A OE2 118 GLU A OE2 1 ATOM 925 N N . ASP A 1 119 ? -8.412 -30.355 -51.362 1.00 51.85 ? 119 ASP A N 119 ASP A N 1 ATOM 926 C CA . ASP A 1 119 ? -9.088 -31.274 -52.272 1.00 51.85 ? 119 ASP A CA 119 ASP A CA 1 ATOM 927 C C . ASP A 1 119 ? -8.389 -31.316 -53.629 1.00 51.85 ? 119 ASP A C 119 ASP A C 1 ATOM 928 O O . ASP A 1 119 ? -8.501 -32.301 -54.361 1.00 51.85 ? 119 ASP A O 119 ASP A O 1 ATOM 929 C CB . ASP A 1 119 ? -10.554 -30.875 -52.448 1.00 51.85 ? 119 ASP A CB 119 ASP A CB 1 ATOM 930 C CG . ASP A 1 119 ? -11.482 -31.584 -51.476 1.00 51.85 ? 119 ASP A CG 119 ASP A CG 1 ATOM 931 O OD1 . ASP A 1 119 ? -11.033 -32.514 -50.772 1.00 51.85 ? 119 ASP A OD1 119 ASP A OD1 1 ATOM 932 O OD2 . ASP A 1 119 ? -12.674 -31.211 -51.417 1.00 51.85 ? 119 ASP A OD2 119 ASP A OD2 1 ATOM 933 N N . GLU A 1 120 ? -7.407 -30.436 -53.921 1.00 45.86 ? 120 GLU A N 120 GLU A N 1 ATOM 934 C CA . GLU A 1 120 ? -6.706 -30.491 -55.201 1.00 45.86 ? 120 GLU A CA 120 GLU A CA 1 ATOM 935 C C . GLU A 1 120 ? -5.333 -31.139 -55.051 1.00 45.86 ? 120 GLU A C 120 GLU A C 1 ATOM 936 O O . GLU A 1 120 ? -4.664 -31.426 -56.046 1.00 45.86 ? 120 GLU A O 120 GLU A O 1 ATOM 937 C CB . GLU A 1 120 ? -6.563 -29.088 -55.797 1.00 45.86 ? 120 GLU A CB 120 GLU A CB 1 ATOM 938 C CG . GLU A 1 120 ? -6.689 -29.048 -57.313 1.00 45.86 ? 120 GLU A CG 120 GLU A CG 1 ATOM 939 C CD . GLU A 1 120 ? -6.535 -27.650 -57.891 1.00 45.86 ? 120 GLU A CD 120 GLU A CD 1 ATOM 940 O OE1 . GLU A 1 120 ? -6.524 -27.506 -59.135 1.00 45.86 ? 120 GLU A OE1 120 GLU A OE1 1 ATOM 941 O OE2 . GLU A 1 120 ? -6.423 -26.692 -57.094 1.00 45.86 ? 120 GLU A OE2 120 GLU A OE2 1 ATOM 942 N N . MET A 1 121 ? -5.127 -31.995 -54.022 1.00 38.92 ? 121 MET A N 121 MET A N 1 ATOM 943 C CA . MET A 1 121 ? -3.878 -32.740 -54.158 1.00 38.92 ? 121 MET A CA 121 MET A CA 1 ATOM 944 C C . MET A 1 121 ? -4.101 -34.227 -53.907 1.00 38.92 ? 121 MET A C 121 MET A C 1 ATOM 945 O O . MET A 1 121 ? -4.357 -34.638 -52.774 1.00 38.92 ? 121 MET A O 121 MET A O 1 ATOM 946 C CB . MET A 1 121 ? -2.821 -32.199 -53.194 1.00 38.92 ? 121 MET A CB 121 MET A CB 1 ATOM 947 C CG . MET A 1 121 ? -2.170 -30.907 -53.660 1.00 38.92 ? 121 MET A CG 121 MET A CG 1 ATOM 948 S SD . MET A 1 121 ? -0.774 -30.395 -52.583 1.00 38.92 ? 121 MET A SD 121 MET A SD 1 ATOM 949 C CE . MET A 1 121 ? -0.290 -32.005 -51.900 1.00 38.92 ? 121 MET A CE 121 MET A CE 1 ATOM 950 N N . ASP A 1 122 ? -4.898 -34.943 -54.700 1.00 34.28 ? 122 ASP A N 122 ASP A N 1 ATOM 951 C CA . ASP A 1 122 ? -4.925 -36.336 -55.135 1.00 34.28 ? 122 ASP A CA 122 ASP A CA 1 ATOM 952 C C . ASP A 1 122 ? -3.530 -36.816 -55.527 1.00 34.28 ? 122 ASP A C 122 ASP A C 1 ATOM 953 O O . ASP A 1 122 ? -2.980 -36.382 -56.542 1.00 34.28 ? 122 ASP A O 122 ASP A O 1 ATOM 954 C CB . ASP A 1 122 ? -5.891 -36.513 -56.308 1.00 34.28 ? 122 ASP A CB 122 ASP A CB 1 ATOM 955 C CG . ASP A 1 122 ? -7.282 -36.939 -55.871 1.00 34.28 ? 122 ASP A CG 122 ASP A CG 1 ATOM 956 O OD1 . ASP A 1 122 ? -7.457 -37.342 -54.701 1.00 34.28 ? 122 ASP A OD1 122 ASP A OD1 1 ATOM 957 O OD2 . ASP A 1 122 ? -8.210 -36.875 -56.705 1.00 34.28 ? 122 ASP A OD2 122 ASP A OD2 1 ATOM 958 N N . ILE A 1 123 ? -2.718 -37.302 -54.655 1.00 33.94 ? 123 ILE A N 123 ILE A N 1 ATOM 959 C CA . ILE A 1 123 ? -1.700 -38.290 -54.996 1.00 33.94 ? 123 ILE A CA 123 ILE A CA 1 ATOM 960 C C . ILE A 1 123 ? -1.828 -39.502 -54.076 1.00 33.94 ? 123 ILE A C 123 ILE A C 1 ATOM 961 O O . ILE A 1 123 ? -1.863 -39.359 -52.852 1.00 33.94 ? 123 ILE A O 123 ILE A O 1 ATOM 962 C CB . ILE A 1 123 ? -0.278 -37.692 -54.901 1.00 33.94 ? 123 ILE A CB 123 ILE A CB 1 ATOM 963 C CG1 . ILE A 1 123 ? -0.126 -36.517 -55.873 1.00 33.94 ? 123 ILE A CG1 123 ILE A CG1 1 ATOM 964 C CG2 . ILE A 1 123 ? 0.779 -38.767 -55.171 1.00 33.94 ? 123 ILE A CG2 123 ILE A CG2 1 ATOM 965 C CD1 . ILE A 1 123 ? 1.155 -35.717 -55.683 1.00 33.94 ? 123 ILE A CD1 123 ILE A CD1 1 ATOM 966 N N . ASP A 1 124 ? -2.447 -40.592 -54.558 1.00 31.68 ? 124 ASP A N 124 ASP A N 1 ATOM 967 C CA . ASP A 1 124 ? -2.256 -42.009 -54.850 1.00 31.68 ? 124 ASP A CA 124 ASP A CA 1 ATOM 968 C C . ASP A 1 124 ? -1.102 -42.587 -54.035 1.00 31.68 ? 124 ASP A C 124 ASP A C 1 ATOM 969 O O . ASP A 1 124 ? 0.003 -42.040 -54.039 1.00 31.68 ? 124 ASP A O 124 ASP A O 1 ATOM 970 C CB . ASP A 1 124 ? -2.002 -42.220 -56.344 1.00 31.68 ? 124 ASP A CB 124 ASP A CB 1 ATOM 971 C CG . ASP A 1 124 ? -3.253 -42.616 -57.108 1.00 31.68 ? 124 ASP A CG 124 ASP A CG 1 ATOM 972 O OD1 . ASP A 1 124 ? -4.283 -42.930 -56.473 1.00 31.68 ? 124 ASP A OD1 124 ASP A OD1 1 ATOM 973 O OD2 . ASP A 1 124 ? -3.208 -42.618 -58.358 1.00 31.68 ? 124 ASP A OD2 124 ASP A OD2 1 ATOM 974 N N . LEU A 1 125 ? -1.291 -43.503 -53.079 1.00 29.82 ? 125 LEU A N 125 LEU A N 1 ATOM 975 C CA . LEU A 1 125 ? -0.843 -44.889 -53.002 1.00 29.82 ? 125 LEU A CA 125 LEU A CA 1 ATOM 976 C C . LEU A 1 125 ? -0.293 -45.207 -51.615 1.00 29.82 ? 125 LEU A C 125 LEU A C 1 ATOM 977 O O . LEU A 1 125 ? 0.574 -44.492 -51.108 1.00 29.82 ? 125 LEU A O 125 LEU A O 1 ATOM 978 C CB . LEU A 1 125 ? 0.226 -45.167 -54.063 1.00 29.82 ? 125 LEU A CB 125 LEU A CB 1 ATOM 979 C CG . LEU A 1 125 ? -0.283 -45.568 -55.448 1.00 29.82 ? 125 LEU A CG 125 LEU A CG 1 ATOM 980 C CD1 . LEU A 1 125 ? 0.712 -45.142 -56.522 1.00 29.82 ? 125 LEU A CD1 125 LEU A CD1 1 ATOM 981 C CD2 . LEU A 1 125 ? -0.535 -47.071 -55.511 1.00 29.82 ? 125 LEU A CD2 125 LEU A CD2 1 ATOM 982 N N . ASP A 1 126 ? -0.919 -46.024 -50.716 1.00 28.87 ? 126 ASP A N 126 ASP A N 1 ATOM 983 C CA . ASP A 1 126 ? -0.702 -47.365 -50.182 1.00 28.87 ? 126 ASP A CA 126 ASP A CA 1 ATOM 984 C C . ASP A 1 126 ? 0.237 -47.331 -48.978 1.00 28.87 ? 126 ASP A C 126 ASP A C 1 ATOM 985 O O . ASP A 1 126 ? 1.385 -46.898 -49.092 1.00 28.87 ? 126 ASP A O 126 ASP A O 1 ATOM 986 C CB . ASP A 1 126 ? -0.138 -48.289 -51.263 1.00 28.87 ? 126 ASP A CB 126 ASP A CB 1 ATOM 987 C CG . ASP A 1 126 ? -1.183 -49.222 -51.850 1.00 28.87 ? 126 ASP A CG 126 ASP A CG 1 ATOM 988 O OD1 . ASP A 1 126 ? -2.324 -49.258 -51.340 1.00 28.87 ? 126 ASP A OD1 126 ASP A OD1 1 ATOM 989 O OD2 . ASP A 1 126 ? -0.862 -49.929 -52.829 1.00 28.87 ? 126 ASP A OD2 126 ASP A OD2 1 ATOM 990 N N . GLY A 1 127 ? -0.207 -47.419 -47.685 1.00 28.67 ? 127 GLY A N 127 GLY A N 1 ATOM 991 C CA . GLY A 1 127 ? 0.155 -48.360 -46.637 1.00 28.67 ? 127 GLY A CA 127 GLY A CA 1 ATOM 992 C C . GLY A 1 127 ? 0.384 -47.696 -45.293 1.00 28.67 ? 127 GLY A C 127 GLY A C 1 ATOM 993 O O . GLY A 1 127 ? 1.160 -46.744 -45.188 1.00 28.67 ? 127 GLY A O 127 GLY A O 1 ATOM 994 N N . GLY A 1 128 ? -0.578 -47.608 -44.316 1.00 30.36 ? 128 GLY A N 128 GLY A N 1 ATOM 995 C CA . GLY A 1 128 ? -0.714 -48.060 -42.941 1.00 30.36 ? 128 GLY A CA 128 GLY A CA 1 ATOM 996 C C . GLY A 1 128 ? 0.196 -47.322 -41.977 1.00 30.36 ? 128 GLY A C 128 GLY A C 1 ATOM 997 O O . GLY A 1 128 ? 1.420 -47.453 -42.048 1.00 30.36 ? 128 GLY A O 128 GLY A O 1 ATOM 998 N N . LYS A 1 129 ? -0.063 -46.056 -41.559 1.00 32.64 ? 129 LYS A N 129 LYS A N 1 ATOM 999 C CA . LYS A 1 129 ? 0.311 -45.535 -40.247 1.00 32.64 ? 129 LYS A CA 129 LYS A CA 1 ATOM 1000 C C . LYS A 1 129 ? -0.549 -44.334 -39.867 1.00 32.64 ? 129 LYS A C 129 LYS A C 1 ATOM 1001 O O . LYS A 1 129 ? -0.686 -43.390 -40.648 1.00 32.64 ? 129 LYS A O 129 LYS A O 1 ATOM 1002 C CB . LYS A 1 129 ? 1.791 -45.148 -40.225 1.00 32.64 ? 129 LYS A CB 129 LYS A CB 1 ATOM 1003 C CG . LYS A 1 129 ? 2.733 -46.318 -39.978 1.00 32.64 ? 129 LYS A CG 129 LYS A CG 1 ATOM 1004 C CD . LYS A 1 129 ? 4.175 -45.852 -39.830 1.00 32.64 ? 129 LYS A CD 129 LYS A CD 1 ATOM 1005 C CE . LYS A 1 129 ? 5.124 -47.024 -39.621 1.00 32.64 ? 129 LYS A CE 129 LYS A CE 1 ATOM 1006 N NZ . LYS A 1 129 ? 6.541 -46.573 -39.480 1.00 32.64 ? 129 LYS A NZ 129 LYS A NZ 1 ATOM 1007 N N . LYS A 1 130 ? -1.808 -44.516 -39.519 1.00 34.98 ? 130 LYS A N 130 LYS A N 1 ATOM 1008 C CA . LYS A 1 130 ? -2.580 -43.747 -38.546 1.00 34.98 ? 130 LYS A CA 130 LYS A CA 1 ATOM 1009 C C . LYS A 1 130 ? -1.878 -42.436 -38.201 1.00 34.98 ? 130 LYS A C 130 LYS A C 1 ATOM 1010 O O . LYS A 1 130 ? -0.855 -42.436 -37.513 1.00 34.98 ? 130 LYS A O 130 LYS A O 1 ATOM 1011 C CB . LYS A 1 130 ? -2.813 -44.566 -37.276 1.00 34.98 ? 130 LYS A CB 130 LYS A CB 1 ATOM 1012 C CG . LYS A 1 130 ? -3.834 -45.683 -37.439 1.00 34.98 ? 130 LYS A CG 130 LYS A CG 1 ATOM 1013 C CD . LYS A 1 130 ? -4.280 -46.233 -36.091 1.00 34.98 ? 130 LYS A CD 130 LYS A CD 1 ATOM 1014 C CE . LYS A 1 130 ? -5.329 -47.325 -36.251 1.00 34.98 ? 130 LYS A CE 130 LYS A CE 1 ATOM 1015 N NZ . LYS A 1 130 ? -5.771 -47.867 -34.931 1.00 34.98 ? 130 LYS A NZ 130 LYS A NZ 1 ATOM 1016 N N . VAL A 1 131 ? -1.535 -41.554 -39.127 1.00 41.70 ? 131 VAL A N 131 VAL A N 1 ATOM 1017 C CA . VAL A 1 131 ? -1.163 -40.162 -38.899 1.00 41.70 ? 131 VAL A CA 131 VAL A CA 1 ATOM 1018 C C . VAL A 1 131 ? -2.284 -39.443 -38.150 1.00 41.70 ? 131 VAL A C 131 VAL A C 1 ATOM 1019 O O . VAL A 1 131 ? -3.415 -39.368 -38.637 1.00 41.70 ? 131 VAL A O 131 VAL A O 1 ATOM 1020 C CB . VAL A 1 131 ? -0.855 -39.432 -40.225 1.00 41.70 ? 131 VAL A CB 131 VAL A CB 1 ATOM 1021 C CG1 . VAL A 1 131 ? -0.468 -37.977 -39.964 1.00 41.70 ? 131 VAL A CG1 131 VAL A CG1 1 ATOM 1022 C CG2 . VAL A 1 131 ? 0.255 -40.155 -40.986 1.00 41.70 ? 131 VAL A CG2 131 VAL A CG2 1 ATOM 1023 N N . LYS A 1 132 ? -2.689 -39.904 -36.924 1.00 40.30 ? 132 LYS A N 132 LYS A N 1 ATOM 1024 C CA . LYS A 1 132 ? -3.278 -39.032 -35.911 1.00 40.30 ? 132 LYS A CA 132 LYS A CA 1 ATOM 1025 C C . LYS A 1 132 ? -3.241 -37.572 -36.353 1.00 40.30 ? 132 LYS A C 132 LYS A C 1 ATOM 1026 O O . LYS A 1 132 ? -2.169 -37.025 -36.618 1.00 40.30 ? 132 LYS A O 132 LYS A O 1 ATOM 1027 C CB . LYS A 1 132 ? -2.550 -39.194 -34.575 1.00 40.30 ? 132 LYS A CB 132 LYS A CB 1 ATOM 1028 C CG . LYS A 1 132 ? -2.931 -40.453 -33.811 1.00 40.30 ? 132 LYS A CG 132 LYS A CG 1 ATOM 1029 C CD . LYS A 1 132 ? -2.347 -40.452 -32.404 1.00 40.30 ? 132 LYS A CD 132 LYS A CD 1 ATOM 1030 C CE . LYS A 1 132 ? -2.741 -41.704 -31.632 1.00 40.30 ? 132 LYS A CE 132 LYS A CE 1 ATOM 1031 N NZ . LYS A 1 132 ? -2.153 -41.717 -30.260 1.00 40.30 ? 132 LYS A NZ 132 LYS A NZ 1 ATOM 1032 N N . GLU A 1 133 ? -3.803 -37.178 -37.383 1.00 41.50 ? 133 GLU A N 133 GLU A N 1 ATOM 1033 C CA . GLU A 1 133 ? -4.556 -35.963 -37.679 1.00 41.50 ? 133 GLU A CA 133 GLU A CA 1 ATOM 1034 C C . GLU A 1 133 ? -4.428 -34.945 -36.549 1.00 41.50 ? 133 GLU A C 133 GLU A C 1 ATOM 1035 O O . GLU A 1 133 ? -4.824 -35.217 -35.414 1.00 41.50 ? 133 GLU A O 133 GLU A O 1 ATOM 1036 C CB . GLU A 1 133 ? -6.030 -36.291 -37.927 1.00 41.50 ? 133 GLU A CB 133 GLU A CB 1 ATOM 1037 C CG . GLU A 1 133 ? -6.380 -36.475 -39.397 1.00 41.50 ? 133 GLU A CG 133 GLU A CG 1 ATOM 1038 C CD . GLU A 1 133 ? -7.868 -36.677 -39.639 1.00 41.50 ? 133 GLU A CD 133 GLU A CD 1 ATOM 1039 O OE1 . GLU A 1 133 ? -8.280 -36.802 -40.814 1.00 41.50 ? 133 GLU A OE1 133 GLU A OE1 1 ATOM 1040 O OE2 . GLU A 1 133 ? -8.627 -36.710 -38.644 1.00 41.50 ? 133 GLU A OE2 133 GLU A OE2 1 ATOM 1041 N N . ASN A 1 134 ? -3.261 -34.406 -36.199 1.00 43.37 ? 134 ASN A N 134 ASN A N 1 ATOM 1042 C CA . ASN A 1 134 ? -2.840 -33.136 -35.617 1.00 43.37 ? 134 ASN A CA 134 ASN A CA 1 ATOM 1043 C C . ASN A 1 134 ? -3.971 -32.112 -35.630 1.00 43.37 ? 134 ASN A C 134 ASN A C 1 ATOM 1044 O O . ASN A 1 134 ? -4.283 -31.538 -36.676 1.00 43.37 ? 134 ASN A O 134 ASN A O 1 ATOM 1045 C CB . ASN A 1 134 ? -1.617 -32.587 -36.354 1.00 43.37 ? 134 ASN A CB 134 ASN A CB 1 ATOM 1046 C CG . ASN A 1 134 ? -0.310 -33.066 -35.755 1.00 43.37 ? 134 ASN A CG 134 ASN A CG 1 ATOM 1047 O OD1 . ASN A 1 134 ? -0.284 -33.620 -34.653 1.00 43.37 ? 134 ASN A OD1 134 ASN A OD1 1 ATOM 1048 N ND2 . ASN A 1 134 ? 0.785 -32.858 -36.476 1.00 43.37 ? 134 ASN A ND2 134 ASN A ND2 1 ATOM 1049 N N . GLU A 1 135 ? -5.188 -32.373 -35.143 1.00 51.20 ? 135 GLU A N 135 GLU A N 1 ATOM 1050 C CA . GLU A 1 135 ? -6.179 -31.374 -34.755 1.00 51.20 ? 135 GLU A CA 135 GLU A CA 1 ATOM 1051 C C . GLU A 1 135 ? -5.510 -30.113 -34.216 1.00 51.20 ? 135 GLU A C 135 GLU A C 1 ATOM 1052 O O . GLU A 1 135 ? -4.605 -30.192 -33.382 1.00 51.20 ? 135 GLU A O 135 GLU A O 1 ATOM 1053 C CB . GLU A 1 135 ? -7.140 -31.947 -33.710 1.00 51.20 ? 135 GLU A CB 135 GLU A CB 1 ATOM 1054 C CG . GLU A 1 135 ? -8.282 -32.758 -34.305 1.00 51.20 ? 135 GLU A CG 135 GLU A CG 1 ATOM 1055 C CD . GLU A 1 135 ? -9.305 -33.201 -33.271 1.00 51.20 ? 135 GLU A CD 135 GLU A CD 1 ATOM 1056 O OE1 . GLU A 1 135 ? -10.335 -33.801 -33.654 1.00 51.20 ? 135 GLU A OE1 135 GLU A OE1 1 ATOM 1057 O OE2 . GLU A 1 135 ? -9.075 -32.946 -32.068 1.00 51.20 ? 135 GLU A OE2 135 GLU A OE2 1 ATOM 1058 N N . LYS A 1 136 ? -4.980 -29.216 -34.979 1.00 56.65 ? 136 LYS A N 136 LYS A N 1 ATOM 1059 C CA . LYS A 1 136 ? -4.517 -27.870 -34.656 1.00 56.65 ? 136 LYS A CA 136 LYS A CA 1 ATOM 1060 C C . LYS A 1 136 ? -5.004 -27.438 -33.275 1.00 56.65 ? 136 LYS A C 136 LYS A C 1 ATOM 1061 O O . LYS A 1 136 ? -6.208 -27.432 -33.009 1.00 56.65 ? 136 LYS A O 136 LYS A O 1 ATOM 1062 C CB . LYS A 1 136 ? -4.989 -26.871 -35.714 1.00 56.65 ? 136 LYS A CB 136 LYS A CB 1 ATOM 1063 C CG . LYS A 1 136 ? -4.225 -26.953 -37.027 1.00 56.65 ? 136 LYS A CG 136 LYS A CG 1 ATOM 1064 C CD . LYS A 1 136 ? -4.632 -25.837 -37.981 1.00 56.65 ? 136 LYS A CD 136 LYS A CD 1 ATOM 1065 C CE . LYS A 1 136 ? -3.909 -25.951 -39.316 1.00 56.65 ? 136 LYS A CE 136 LYS A CE 1 ATOM 1066 N NZ . LYS A 1 136 ? -4.270 -24.833 -40.239 1.00 56.65 ? 136 LYS A NZ 136 LYS A NZ 1 ATOM 1067 N N . LYS A 1 137 ? -4.477 -27.961 -32.264 1.00 63.26 ? 137 LYS A N 137 LYS A N 1 ATOM 1068 C CA . LYS A 1 137 ? -4.694 -27.612 -30.863 1.00 63.26 ? 137 LYS A CA 137 LYS A CA 1 ATOM 1069 C C . LYS A 1 137 ? -4.939 -26.114 -30.701 1.00 63.26 ? 137 LYS A C 137 LYS A C 1 ATOM 1070 O O . LYS A 1 137 ? -4.347 -25.302 -31.416 1.00 63.26 ? 137 LYS A O 137 LYS A O 1 ATOM 1071 C CB . LYS A 1 137 ? -3.500 -28.043 -30.010 1.00 63.26 ? 137 LYS A CB 137 LYS A CB 1 ATOM 1072 C CG . LYS A 1 137 ? -3.327 -29.551 -29.904 1.00 63.26 ? 137 LYS A CG 137 LYS A CG 1 ATOM 1073 C CD . LYS A 1 137 ? -2.156 -29.917 -29.001 1.00 63.26 ? 137 LYS A CD 137 LYS A CD 1 ATOM 1074 C CE . LYS A 1 137 ? -1.941 -31.424 -28.947 1.00 63.26 ? 137 LYS A CE 137 LYS A CE 1 ATOM 1075 N NZ . LYS A 1 137 ? -0.775 -31.786 -28.087 1.00 63.26 ? 137 LYS A NZ 137 LYS A NZ 1 ATOM 1076 N N . SER A 1 138 ? -6.096 -25.765 -30.075 1.00 73.72 ? 138 SER A N 138 SER A N 1 ATOM 1077 C CA . SER A 1 138 ? -6.450 -24.397 -29.708 1.00 73.72 ? 138 SER A CA 138 SER A CA 1 ATOM 1078 C C . SER A 1 138 ? -5.331 -23.730 -28.916 1.00 73.72 ? 138 SER A C 138 SER A C 1 ATOM 1079 O O . SER A 1 138 ? -4.527 -24.409 -28.275 1.00 73.72 ? 138 SER A O 138 SER A O 1 ATOM 1080 C CB . SER A 1 138 ? -7.744 -24.379 -28.892 1.00 73.72 ? 138 SER A CB 138 SER A CB 1 ATOM 1081 O OG . SER A 1 138 ? -7.943 -23.110 -28.293 1.00 73.72 ? 138 SER A OG 138 SER A OG 1 ATOM 1082 N N . SER A 1 139 ? -4.979 -22.513 -29.202 1.00 75.47 ? 139 SER A N 139 SER A N 1 ATOM 1083 C CA . SER A 1 139 ? -3.990 -21.664 -28.546 1.00 75.47 ? 139 SER A CA 139 SER A CA 1 ATOM 1084 C C . SER A 1 139 ? -4.053 -21.811 -27.029 1.00 75.47 ? 139 SER A C 139 SER A C 1 ATOM 1085 O O . SER A 1 139 ? -3.018 -21.864 -26.362 1.00 75.47 ? 139 SER A O 139 SER A O 1 ATOM 1086 C CB . SER A 1 139 ? -4.199 -20.199 -28.933 1.00 75.47 ? 139 SER A CB 139 SER A CB 1 ATOM 1087 O OG . SER A 1 139 ? -5.453 -19.730 -28.469 1.00 75.47 ? 139 SER A OG 139 SER A OG 1 ATOM 1088 N N . LEU A 1 140 ? -5.232 -21.860 -26.403 1.00 78.22 ? 140 LEU A N 140 LEU A N 1 ATOM 1089 C CA . LEU A 1 140 ? -5.435 -22.002 -24.965 1.00 78.22 ? 140 LEU A CA 140 LEU A CA 1 ATOM 1090 C C . LEU A 1 140 ? -4.909 -23.346 -24.472 1.00 78.22 ? 140 LEU A C 140 LEU A C 1 ATOM 1091 O O . LEU A 1 140 ? -4.267 -23.418 -23.421 1.00 78.22 ? 140 LEU A O 140 LEU A O 1 ATOM 1092 C CB . LEU A 1 140 ? -6.919 -21.863 -24.616 1.00 78.22 ? 140 LEU A CB 140 LEU A CB 1 ATOM 1093 C CG . LEU A 1 140 ? -7.261 -21.783 -23.127 1.00 78.22 ? 140 LEU A CG 140 LEU A CG 1 ATOM 1094 C CD1 . LEU A 1 140 ? -8.535 -20.971 -22.919 1.00 78.22 ? 140 LEU A CD1 140 LEU A CD1 1 ATOM 1095 C CD2 . LEU A 1 140 ? -7.408 -23.181 -22.537 1.00 78.22 ? 140 LEU A CD2 140 LEU A CD2 1 ATOM 1096 N N . THR A 1 141 ? -5.155 -24.389 -25.237 1.00 81.06 ? 141 THR A N 141 THR A N 1 ATOM 1097 C CA . THR A 1 141 ? -4.695 -25.724 -24.873 1.00 81.06 ? 141 THR A CA 141 THR A CA 1 ATOM 1098 C C . THR A 1 141 ? -3.172 -25.804 -24.924 1.00 81.06 ? 141 THR A C 141 THR A C 1 ATOM 1099 O O . THR A 1 141 ? -2.550 -26.451 -24.078 1.00 81.06 ? 141 THR A O 141 THR A O 1 ATOM 1100 C CB . THR A 1 141 ? -5.298 -26.796 -25.800 1.00 81.06 ? 141 THR A CB 141 THR A CB 1 ATOM 1101 O OG1 . THR A 1 141 ? -5.086 -26.413 -27.165 1.00 81.06 ? 141 THR A OG1 141 THR A OG1 1 ATOM 1102 C CG2 . THR A 1 141 ? -6.796 -26.954 -25.556 1.00 81.06 ? 141 THR A CG2 141 THR A CG2 1 ATOM 1103 N N . LEU A 1 142 ? -2.613 -25.119 -25.824 1.00 82.01 ? 142 LEU A N 142 LEU A N 1 ATOM 1104 C CA . LEU A 1 142 ? -1.160 -25.069 -25.940 1.00 82.01 ? 142 LEU A CA 142 LEU A CA 1 ATOM 1105 C C . LEU A 1 142 ? -0.541 -24.386 -24.725 1.00 82.01 ? 142 LEU A C 142 LEU A C 1 ATOM 1106 O O . LEU A 1 142 ? 0.480 -24.841 -24.205 1.00 82.01 ? 142 LEU A O 142 LEU A O 1 ATOM 1107 C CB . LEU A 1 142 ? -0.749 -24.333 -27.218 1.00 82.01 ? 142 LEU A CB 142 LEU A CB 1 ATOM 1108 C CG . LEU A 1 142 ? -0.987 -25.074 -28.534 1.00 82.01 ? 142 LEU A CG 142 LEU A CG 1 ATOM 1109 C CD1 . LEU A 1 142 ? -0.678 -24.165 -29.719 1.00 82.01 ? 142 LEU A CD1 142 LEU A CD1 1 ATOM 1110 C CD2 . LEU A 1 142 ? -0.143 -26.343 -28.594 1.00 82.01 ? 142 LEU A CD2 142 LEU A CD2 1 ATOM 1111 N N . VAL A 1 143 ? -1.204 -23.320 -24.299 1.00 82.39 ? 143 VAL A N 143 VAL A N 1 ATOM 1112 C CA . VAL A 1 143 ? -0.741 -22.569 -23.136 1.00 82.39 ? 143 VAL A CA 143 VAL A CA 1 ATOM 1113 C C . VAL A 1 143 ? -0.869 -23.429 -21.881 1.00 82.39 ? 143 VAL A C 143 VAL A C 1 ATOM 1114 O O . VAL A 1 143 ? 0.052 -23.486 -21.063 1.00 82.39 ? 143 VAL A O 143 VAL A O 1 ATOM 1115 C CB . VAL A 1 143 ? -1.527 -21.251 -22.962 1.00 82.39 ? 143 VAL A CB 143 VAL A CB 1 ATOM 1116 C CG1 . VAL A 1 143 ? -1.150 -20.567 -21.649 1.00 82.39 ? 143 VAL A CG1 143 VAL A CG1 1 ATOM 1117 C CG2 . VAL A 1 143 ? -1.275 -20.319 -24.145 1.00 82.39 ? 143 VAL A CG2 143 VAL A CG2 1 ATOM 1118 N N . LYS A 1 144 ? -1.965 -24.077 -21.707 1.00 83.08 ? 144 LYS A N 144 LYS A N 1 ATOM 1119 C CA . LYS A 1 144 ? -2.198 -24.953 -20.562 1.00 83.08 ? 144 LYS A CA 144 LYS A CA 1 ATOM 1120 C C . LYS A 1 144 ? -1.162 -26.071 -20.506 1.00 83.08 ? 144 LYS A C 144 LYS A C 1 ATOM 1121 O O . LYS A 1 144 ? -0.643 -26.391 -19.434 1.00 83.08 ? 144 LYS A O 144 LYS A O 1 ATOM 1122 C CB . LYS A 1 144 ? -3.607 -25.546 -20.617 1.00 83.08 ? 144 LYS A CB 144 LYS A CB 1 ATOM 1123 C CG . LYS A 1 144 ? -4.705 -24.570 -20.221 1.00 83.08 ? 144 LYS A CG 144 LYS A CG 1 ATOM 1124 C CD . LYS A 1 144 ? -6.059 -25.261 -20.124 1.00 83.08 ? 144 LYS A CD 144 LYS A CD 1 ATOM 1125 C CE . LYS A 1 144 ? -7.144 -24.304 -19.649 1.00 83.08 ? 144 LYS A CE 144 LYS A CE 1 ATOM 1126 N NZ . LYS A 1 144 ? -8.474 -24.976 -19.558 1.00 83.08 ? 144 LYS A NZ 144 LYS A NZ 1 ATOM 1127 N N . GLU A 1 145 ? -0.850 -26.668 -21.607 1.00 83.71 ? 145 GLU A N 145 GLU A N 1 ATOM 1128 C CA . GLU A 1 145 ? 0.132 -27.746 -21.674 1.00 83.71 ? 145 GLU A CA 145 GLU A CA 1 ATOM 1129 C C . GLU A 1 145 ? 1.528 -27.243 -21.317 1.00 83.71 ? 145 GLU A C 145 GLU A C 1 ATOM 1130 O O . GLU A 1 145 ? 2.281 -27.928 -20.622 1.00 83.71 ? 145 GLU A O 145 GLU A O 1 ATOM 1131 C CB . GLU A 1 145 ? 0.141 -28.380 -23.067 1.00 83.71 ? 145 GLU A CB 145 GLU A CB 1 ATOM 1132 C CG . GLU A 1 145 ? -1.029 -29.318 -23.324 1.00 83.71 ? 145 GLU A CG 145 GLU A CG 1 ATOM 1133 C CD . GLU A 1 145 ? -1.004 -29.943 -24.709 1.00 83.71 ? 145 GLU A CD 145 GLU A CD 1 ATOM 1134 O OE1 . GLU A 1 145 ? -1.922 -30.730 -25.037 1.00 83.71 ? 145 GLU A OE1 145 GLU A OE1 1 ATOM 1135 O OE2 . GLU A 1 145 ? -0.059 -29.645 -25.473 1.00 83.71 ? 145 GLU A OE2 145 GLU A OE2 1 ATOM 1136 N N . ALA A 1 146 ? 1.792 -26.084 -21.835 1.00 82.21 ? 146 ALA A N 146 ALA A N 1 ATOM 1137 C CA . ALA A 1 146 ? 3.085 -25.479 -21.523 1.00 82.21 ? 146 ALA A CA 146 ALA A CA 1 ATOM 1138 C C . ALA A 1 146 ? 3.224 -25.226 -20.024 1.00 82.21 ? 146 ALA A C 146 ALA A C 1 ATOM 1139 O O . ALA A 1 146 ? 4.274 -25.499 -19.438 1.00 82.21 ? 146 ALA A O 146 ALA A O 1 ATOM 1140 C CB . ALA A 1 146 ? 3.264 -24.177 -22.298 1.00 82.21 ? 146 ALA A CB 146 ALA A CB 1 ATOM 1141 N N . LEU A 1 147 ? 2.148 -24.731 -19.454 1.00 83.56 ? 147 LEU A N 147 LEU A N 1 ATOM 1142 C CA . LEU A 1 147 ? 2.157 -24.420 -18.029 1.00 83.56 ? 147 LEU A CA 147 LEU A CA 1 ATOM 1143 C C . LEU A 1 147 ? 2.215 -25.696 -17.195 1.00 83.56 ? 147 LEU A C 147 LEU A C 1 ATOM 1144 O O . LEU A 1 147 ? 2.923 -25.751 -16.187 1.00 83.56 ? 147 LEU A O 147 LEU A O 1 ATOM 1145 C CB . LEU A 1 147 ? 0.917 -23.605 -17.650 1.00 83.56 ? 147 LEU A CB 147 LEU A CB 1 ATOM 1146 C CG . LEU A 1 147 ? 0.902 -22.144 -18.102 1.00 83.56 ? 147 LEU A CG 147 LEU A CG 1 ATOM 1147 C CD1 . LEU A 1 147 ? -0.468 -21.524 -17.846 1.00 83.56 ? 147 LEU A CD1 147 LEU A CD1 1 ATOM 1148 C CD2 . LEU A 1 147 ? 1.994 -21.353 -17.391 1.00 83.56 ? 147 LEU A CD2 147 LEU A CD2 1 ATOM 1149 N N . TRP A 1 148 ? 1.532 -26.736 -17.665 1.00 86.08 ? 148 TRP A N 148 TRP A N 1 ATOM 1150 C CA . TRP A 1 148 ? 1.570 -28.020 -16.973 1.00 86.08 ? 148 TRP A CA 148 TRP A CA 1 ATOM 1151 C C . TRP A 1 148 ? 2.981 -28.601 -16.980 1.00 86.08 ? 148 TRP A C 148 TRP A C 1 ATOM 1152 O O . TRP A 1 148 ? 3.406 -29.227 -16.007 1.00 86.08 ? 148 TRP A O 148 TRP A O 1 ATOM 1153 C CB . TRP A 1 148 ? 0.595 -29.009 -17.618 1.00 86.08 ? 148 TRP A CB 148 TRP A CB 1 ATOM 1154 C CG . TRP A 1 148 ? -0.764 -29.025 -16.984 1.00 86.08 ? 148 TRP A CG 148 TRP A CG 1 ATOM 1155 C CD1 . TRP A 1 148 ? -1.942 -28.622 -17.549 1.00 86.08 ? 148 TRP A CD1 148 TRP A CD1 1 ATOM 1156 C CD2 . TRP A 1 148 ? -1.083 -29.463 -15.660 1.00 86.08 ? 148 TRP A CD2 148 TRP A CD2 1 ATOM 1157 N NE1 . TRP A 1 148 ? -2.975 -28.784 -16.656 1.00 86.08 ? 148 TRP A NE1 148 TRP A NE1 1 ATOM 1158 C CE2 . TRP A 1 148 ? -2.475 -29.298 -15.489 1.00 86.08 ? 148 TRP A CE2 148 TRP A CE2 1 ATOM 1159 C CE3 . TRP A 1 148 ? -0.326 -29.980 -14.600 1.00 86.08 ? 148 TRP A CE3 148 TRP A CE3 1 ATOM 1160 C CZ2 . TRP A 1 148 ? -3.127 -29.632 -14.300 1.00 86.08 ? 148 TRP A CZ2 148 TRP A CZ2 1 ATOM 1161 C CZ3 . TRP A 1 148 ? -0.976 -30.312 -13.417 1.00 86.08 ? 148 TRP A CZ3 148 TRP A CZ3 1 ATOM 1162 C CH2 . TRP A 1 148 ? -2.363 -30.136 -13.279 1.00 86.08 ? 148 TRP A CH2 148 TRP A CH2 1 ATOM 1163 N N . SER A 1 149 ? 3.654 -28.394 -18.050 1.00 83.81 ? 149 SER A N 149 SER A N 1 ATOM 1164 C CA . SER A 1 149 ? 5.013 -28.910 -18.177 1.00 83.81 ? 149 SER A CA 149 SER A CA 1 ATOM 1165 C C . SER A 1 149 ? 5.945 -28.272 -17.152 1.00 83.81 ? 149 SER A C 149 SER A C 1 ATOM 1166 O O . SER A 1 149 ? 6.792 -28.951 -16.568 1.00 83.81 ? 149 SER A O 149 SER A O 1 ATOM 1167 C CB . SER A 1 149 ? 5.550 -28.665 -19.588 1.00 83.81 ? 149 SER A CB 149 SER A CB 1 ATOM 1168 O OG . SER A 1 149 ? 5.772 -27.283 -19.809 1.00 83.81 ? 149 SER A OG 149 SER A OG 1 ATOM 1169 N N . VAL A 1 150 ? 5.751 -27.020 -16.929 1.00 80.97 ? 150 VAL A N 150 VAL A N 1 ATOM 1170 C CA . VAL A 1 150 ? 6.581 -26.282 -15.982 1.00 80.97 ? 150 VAL A CA 150 VAL A CA 1 ATOM 1171 C C . VAL A 1 150 ? 6.282 -26.750 -14.559 1.00 80.97 ? 150 VAL A C 150 VAL A C 1 ATOM 1172 O O . VAL A 1 150 ? 7.198 -26.935 -13.754 1.00 80.97 ? 150 VAL A O 150 VAL A O 1 ATOM 1173 C CB . VAL A 1 150 ? 6.359 -24.758 -16.100 1.00 80.97 ? 150 VAL A CB 150 VAL A CB 1 ATOM 1174 C CG1 . VAL A 1 150 ? 7.115 -24.015 -15.000 1.00 80.97 ? 150 VAL A CG1 150 VAL A CG1 1 ATOM 1175 C CG2 . VAL A 1 150 ? 6.791 -24.261 -17.478 1.00 80.97 ? 150 VAL A CG2 150 VAL A CG2 1 ATOM 1176 N N . ILE A 1 151 ? 5.056 -26.915 -14.296 1.00 81.78 ? 151 ILE A N 151 ILE A N 1 ATOM 1177 C CA . ILE A 1 151 ? 4.625 -27.343 -12.969 1.00 81.78 ? 151 ILE A CA 151 ILE A CA 1 ATOM 1178 C C . ILE A 1 151 ? 5.162 -28.743 -12.679 1.00 81.78 ? 151 ILE A C 151 ILE A C 1 ATOM 1179 O O . ILE A 1 151 ? 5.628 -29.018 -11.571 1.00 81.78 ? 151 ILE A O 151 ILE A O 1 ATOM 1180 C CB . ILE A 1 151 ? 3.086 -27.322 -12.840 1.00 81.78 ? 151 ILE A CB 151 ILE A CB 1 ATOM 1181 C CG1 . ILE A 1 151 ? 2.564 -25.882 -12.909 1.00 81.78 ? 151 ILE A CG1 151 ILE A CG1 1 ATOM 1182 C CG2 . ILE A 1 151 ? 2.643 -28.003 -11.542 1.00 81.78 ? 151 ILE A CG2 151 ILE A CG2 1 ATOM 1183 C CD1 . ILE A 1 151 ? 1.048 -25.776 -12.995 1.00 81.78 ? 151 ILE A CD1 151 ILE A CD1 1 ATOM 1184 N N . ASP A 1 152 ? 5.146 -29.641 -13.706 1.00 82.01 ? 152 ASP A N 152 ASP A N 1 ATOM 1185 C CA . ASP A 1 152 ? 5.611 -31.016 -13.555 1.00 82.01 ? 152 ASP A CA 152 ASP A CA 1 ATOM 1186 C C . ASP A 1 152 ? 7.128 -31.068 -13.385 1.00 82.01 ? 152 ASP A C 152 ASP A C 1 ATOM 1187 O O . ASP A 1 152 ? 7.644 -31.880 -12.615 1.00 82.01 ? 152 ASP A O 152 ASP A O 1 ATOM 1188 C CB . ASP A 1 152 ? 5.188 -31.862 -14.758 1.00 82.01 ? 152 ASP A CB 152 ASP A CB 1 ATOM 1189 C CG . ASP A 1 152 ? 3.725 -32.266 -14.713 1.00 82.01 ? 152 ASP A CG 152 ASP A CG 1 ATOM 1190 O OD1 . ASP A 1 152 ? 3.104 -32.190 -13.631 1.00 82.01 ? 152 ASP A OD1 152 ASP A OD1 1 ATOM 1191 O OD2 . ASP A 1 152 ? 3.189 -32.667 -15.769 1.00 82.01 ? 152 ASP A OD2 152 ASP A OD2 1 ATOM 1192 N N . ASP A 1 153 ? 7.804 -30.142 -14.103 1.00 75.05 ? 153 ASP A N 153 ASP A N 1 ATOM 1193 C CA . ASP A 1 153 ? 9.259 -30.079 -14.009 1.00 75.05 ? 153 ASP A CA 153 ASP A CA 1 ATOM 1194 C C . ASP A 1 153 ? 9.700 -29.617 -12.622 1.00 75.05 ? 153 ASP A C 153 ASP A C 1 ATOM 1195 O O . ASP A 1 153 ? 10.681 -30.126 -12.075 1.00 75.05 ? 153 ASP A O 153 ASP A O 1 ATOM 1196 C CB . ASP A 1 153 ? 9.826 -29.144 -15.080 1.00 75.05 ? 153 ASP A CB 153 ASP A CB 1 ATOM 1197 C CG . ASP A 1 153 ? 9.776 -29.742 -16.475 1.00 75.05 ? 153 ASP A CG 153 ASP A CG 1 ATOM 1198 O OD1 . ASP A 1 153 ? 9.529 -30.960 -16.609 1.00 75.05 ? 153 ASP A OD1 153 ASP A OD1 1 ATOM 1199 O OD2 . ASP A 1 153 ? 9.989 -28.988 -17.449 1.00 75.05 ? 153 ASP A OD2 153 ASP A OD2 1 ATOM 1200 N N . THR A 1 154 ? 8.973 -28.641 -12.116 1.00 69.68 ? 154 THR A N 154 THR A N 1 ATOM 1201 C CA . THR A 1 154 ? 9.309 -28.102 -10.803 1.00 69.68 ? 154 THR A CA 154 THR A CA 1 ATOM 1202 C C . THR A 1 154 ? 9.011 -29.123 -9.708 1.00 69.68 ? 154 THR A C 154 THR A C 1 ATOM 1203 O O . THR A 1 154 ? 9.725 -29.190 -8.705 1.00 69.68 ? 154 THR A O 154 THR A O 1 ATOM 1204 C CB . THR A 1 154 ? 8.536 -26.801 -10.519 1.00 69.68 ? 154 THR A CB 154 THR A CB 1 ATOM 1205 O OG1 . THR A 1 154 ? 7.138 -27.024 -10.740 1.00 69.68 ? 154 THR A OG1 154 THR A OG1 1 ATOM 1206 C CG2 . THR A 1 154 ? 9.009 -25.671 -11.427 1.00 69.68 ? 154 THR A CG2 154 THR A CG2 1 ATOM 1207 N N . ALA A 1 155 ? 7.901 -29.803 -9.859 1.00 66.78 ? 155 ALA A N 155 ALA A N 1 ATOM 1208 C CA . ALA A 1 155 ? 7.547 -30.844 -8.897 1.00 66.78 ? 155 ALA A CA 155 ALA A CA 1 ATOM 1209 C C . ALA A 1 155 ? 8.602 -31.947 -8.870 1.00 66.78 ? 155 ALA A C 155 ALA A C 1 ATOM 1210 O O . ALA A 1 155 ? 8.882 -32.520 -7.814 1.00 66.78 ? 155 ALA A O 155 ALA A O 1 ATOM 1211 C CB . ALA A 1 155 ? 6.177 -31.431 -9.228 1.00 66.78 ? 155 ALA A CB 155 ALA A CB 1 ATOM 1212 N N . SER A 1 156 ? 9.287 -32.163 -10.027 1.00 63.04 ? 156 SER A N 156 SER A N 1 ATOM 1213 C CA . SER A 1 156 ? 10.261 -33.243 -10.148 1.00 63.04 ? 156 SER A CA 156 SER A CA 1 ATOM 1214 C C . SER A 1 156 ? 11.626 -32.818 -9.618 1.00 63.04 ? 156 SER A C 156 SER A C 1 ATOM 1215 O O . SER A 1 156 ? 12.346 -33.624 -9.025 1.00 63.04 ? 156 SER A O 156 SER A O 1 ATOM 1216 C CB . SER A 1 156 ? 10.386 -33.691 -11.604 1.00 63.04 ? 156 SER A CB 156 SER A CB 1 ATOM 1217 O OG . SER A 1 156 ? 10.704 -32.593 -12.442 1.00 63.04 ? 156 SER A OG 156 SER A OG 1 ATOM 1218 N N . GLN A 1 157 ? 11.949 -31.467 -9.749 1.00 54.41 ? 157 GLN A N 157 GLN A N 1 ATOM 1219 C CA . GLN A 1 157 ? 13.282 -30.961 -9.441 1.00 54.41 ? 157 GLN A CA 157 GLN A CA 1 ATOM 1220 C C . GLN A 1 157 ? 13.342 -30.390 -8.027 1.00 54.41 ? 157 GLN A C 157 GLN A C 1 ATOM 1221 O O . GLN A 1 157 ? 14.401 -30.386 -7.398 1.00 54.41 ? 157 GLN A O 157 GLN A O 1 ATOM 1222 C CB . GLN A 1 157 ? 13.699 -29.895 -10.456 1.00 54.41 ? 157 GLN A CB 157 GLN A CB 1 ATOM 1223 C CG . GLN A 1 157 ? 14.010 -30.450 -11.839 1.00 54.41 ? 157 GLN A CG 157 GLN A CG 1 ATOM 1224 C CD . GLN A 1 157 ? 14.383 -29.369 -12.836 1.00 54.41 ? 157 GLN A CD 157 GLN A CD 1 ATOM 1225 O OE1 . GLN A 1 157 ? 14.347 -28.175 -12.519 1.00 54.41 ? 157 GLN A OE1 157 GLN A OE1 1 ATOM 1226 N NE2 . GLN A 1 157 ? 14.744 -29.778 -14.047 1.00 54.41 ? 157 GLN A NE2 157 GLN A NE2 1 ATOM 1227 N N . GLY A 1 158 ? 12.257 -30.515 -7.201 1.00 54.13 ? 158 GLY A N 158 GLY A N 1 ATOM 1228 C CA . GLY A 1 158 ? 12.270 -29.924 -5.872 1.00 54.13 ? 158 GLY A CA 158 GLY A CA 1 ATOM 1229 C C . GLY A 1 158 ? 12.797 -28.502 -5.857 1.00 54.13 ? 158 GLY A C 158 GLY A C 1 ATOM 1230 O O . GLY A 1 158 ? 13.633 -28.136 -6.685 1.00 54.13 ? 158 GLY A O 158 GLY A O 1 ATOM 1231 N N . LEU A 1 159 ? 11.997 -27.428 -5.635 1.00 54.83 ? 159 LEU A N 159 LEU A N 1 ATOM 1232 C CA . LEU A 1 159 ? 12.393 -26.030 -5.513 1.00 54.83 ? 159 LEU A CA 159 LEU A CA 1 ATOM 1233 C C . LEU A 1 159 ? 13.731 -25.905 -4.791 1.00 54.83 ? 159 LEU A C 159 LEU A C 1 ATOM 1234 O O . LEU A 1 159 ? 13.888 -26.406 -3.675 1.00 54.83 ? 159 LEU A O 159 LEU A O 1 ATOM 1235 C CB . LEU A 1 159 ? 11.321 -25.231 -4.767 1.00 54.83 ? 159 LEU A CB 159 LEU A CB 1 ATOM 1236 C CG . LEU A 1 159 ? 11.214 -23.747 -5.117 1.00 54.83 ? 159 LEU A CG 159 LEU A CG 1 ATOM 1237 C CD1 . LEU A 1 159 ? 10.071 -23.515 -6.100 1.00 54.83 ? 159 LEU A CD1 159 LEU A CD1 1 ATOM 1238 C CD2 . LEU A 1 159 ? 11.019 -22.912 -3.856 1.00 54.83 ? 159 LEU A CD2 159 LEU A CD2 1 ATOM 1239 N N . ILE A 1 160 ? 14.867 -25.918 -5.457 1.00 55.84 ? 160 ILE A N 160 ILE A N 1 ATOM 1240 C CA . ILE A 1 160 ? 16.158 -25.744 -4.799 1.00 55.84 ? 160 ILE A CA 160 ILE A CA 1 ATOM 1241 C C . ILE A 1 160 ? 16.207 -24.382 -4.111 1.00 55.84 ? 160 ILE A C 160 ILE A C 1 ATOM 1242 O O . ILE A 1 160 ? 16.144 -23.343 -4.773 1.00 55.84 ? 160 ILE A O 160 ILE A O 1 ATOM 1243 C CB . ILE A 1 160 ? 17.326 -25.881 -5.802 1.00 55.84 ? 160 ILE A CB 160 ILE A CB 1 ATOM 1244 C CG1 . ILE A 1 160 ? 17.269 -27.241 -6.506 1.00 55.84 ? 160 ILE A CG1 160 ILE A CG1 1 ATOM 1245 C CG2 . ILE A 1 160 ? 18.670 -25.687 -5.094 1.00 55.84 ? 160 ILE A CG2 160 ILE A CG2 1 ATOM 1246 C CD1 . ILE A 1 160 ? 18.193 -27.354 -7.711 1.00 55.84 ? 160 ILE A CD1 160 ILE A CD1 1 ATOM 1247 N N . ILE A 1 161 ? 15.789 -24.301 -2.869 1.00 58.08 ? 161 ILE A N 161 ILE A N 1 ATOM 1248 C CA . ILE A 1 161 ? 15.957 -23.085 -2.079 1.00 58.08 ? 161 ILE A CA 161 ILE A CA 1 ATOM 1249 C C . ILE A 1 161 ? 17.276 -23.146 -1.313 1.00 58.08 ? 161 ILE A C 161 ILE A C 1 ATOM 1250 O O . ILE A 1 161 ? 17.553 -24.127 -0.618 1.00 58.08 ? 161 ILE A O 161 ILE A O 1 ATOM 1251 C CB . ILE A 1 161 ? 14.778 -22.879 -1.102 1.00 58.08 ? 161 ILE A CB 161 ILE A CB 1 ATOM 1252 C CG1 . ILE A 1 161 ? 13.448 -22.869 -1.865 1.00 58.08 ? 161 ILE A CG1 161 ILE A CG1 1 ATOM 1253 C CG2 . ILE A 1 161 ? 14.960 -21.587 -0.301 1.00 58.08 ? 161 ILE A CG2 161 ILE A CG2 1 ATOM 1254 C CD1 . ILE A 1 161 ? 12.219 -22.920 -0.967 1.00 58.08 ? 161 ILE A CD1 161 ILE A CD1 1 ATOM 1255 N N . GLU A 1 162 ? 18.282 -22.455 -1.712 1.00 57.42 ? 162 GLU A N 162 GLU A N 1 ATOM 1256 C CA . GLU A 1 162 ? 19.615 -22.416 -1.119 1.00 57.42 ? 162 GLU A CA 162 GLU A CA 1 ATOM 1257 C C . GLU A 1 162 ? 19.561 -21.946 0.331 1.00 57.42 ? 162 GLU A C 162 GLU A C 1 ATOM 1258 O O . GLU A 1 162 ? 18.860 -20.984 0.652 1.00 57.42 ? 162 GLU A O 162 GLU A O 1 ATOM 1259 C CB . GLU A 1 162 ? 20.540 -21.506 -1.933 1.00 57.42 ? 162 GLU A CB 162 GLU A CB 1 ATOM 1260 C CG . GLU A 1 162 ? 20.890 -22.056 -3.308 1.00 57.42 ? 162 GLU A CG 162 GLU A CG 1 ATOM 1261 C CD . GLU A 1 162 ? 21.887 -21.193 -4.063 1.00 57.42 ? 162 GLU A CD 162 GLU A CD 1 ATOM 1262 O OE1 . GLU A 1 162 ? 22.311 -21.585 -5.174 1.00 57.42 ? 162 GLU A OE1 162 GLU A OE1 1 ATOM 1263 O OE2 . GLU A 1 162 ? 22.248 -20.115 -3.540 1.00 57.42 ? 162 GLU A OE2 162 GLU A OE2 1 ATOM 1264 N N . ASN A 1 163 ? 19.920 -22.853 1.298 1.00 52.71 ? 163 ASN A N 163 ASN A N 1 ATOM 1265 C CA . ASN A 1 163 ? 20.006 -22.639 2.739 1.00 52.71 ? 163 ASN A CA 163 ASN A CA 1 ATOM 1266 C C . ASN A 1 163 ? 21.306 -21.938 3.124 1.00 52.71 ? 163 ASN A C 163 ASN A C 1 ATOM 1267 O O . ASN A 1 163 ? 22.395 -22.431 2.824 1.00 52.71 ? 163 ASN A O 163 ASN A O 1 ATOM 1268 C CB . ASN A 1 163 ? 19.877 -23.967 3.488 1.00 52.71 ? 163 ASN A CB 163 ASN A CB 1 ATOM 1269 C CG . ASN A 1 163 ? 18.465 -24.519 3.457 1.00 52.71 ? 163 ASN A CG 163 ASN A CG 1 ATOM 1270 O OD1 . ASN A 1 163 ? 17.508 -23.794 3.175 1.00 52.71 ? 163 ASN A OD1 163 ASN A OD1 1 ATOM 1271 N ND2 . ASN A 1 163 ? 18.326 -25.807 3.747 1.00 52.71 ? 163 ASN A ND2 163 ASN A ND2 1 ATOM 1272 N N . GLY A 1 164 ? 21.399 -20.548 3.225 1.00 62.53 ? 164 GLY A N 164 GLY A N 1 ATOM 1273 C CA . GLY A 1 164 ? 22.497 -19.814 3.836 1.00 62.53 ? 164 GLY A CA 164 GLY A CA 1 ATOM 1274 C C . GLY A 1 164 ? 22.312 -19.595 5.326 1.00 62.53 ? 164 GLY A C 164 GLY A C 1 ATOM 1275 O O . GLY A 1 164 ? 21.559 -20.322 5.977 1.00 62.53 ? 164 GLY A O 164 GLY A O 1 ATOM 1276 N N . GLN A 1 165 ? 23.310 -18.930 6.133 1.00 78.81 ? 165 GLN A N 165 GLN A N 1 ATOM 1277 C CA . GLN A 1 165 ? 23.328 -18.577 7.549 1.00 78.81 ? 165 GLN A CA 165 GLN A CA 1 ATOM 1278 C C . GLN A 1 165 ? 22.079 -17.790 7.936 1.00 78.81 ? 165 GLN A C 165 GLN A C 1 ATOM 1279 O O . GLN A 1 165 ? 21.743 -17.690 9.117 1.00 78.81 ? 165 GLN A O 165 GLN A O 1 ATOM 1280 C CB . GLN A 1 165 ? 24.583 -17.769 7.885 1.00 78.81 ? 165 GLN A CB 165 GLN A CB 1 ATOM 1281 C CG . GLN A 1 165 ? 25.875 -18.568 7.780 1.00 78.81 ? 165 GLN A CG 165 GLN A CG 1 ATOM 1282 C CD . GLN A 1 165 ? 25.936 -19.718 8.769 1.00 78.81 ? 165 GLN A CD 165 GLN A CD 1 ATOM 1283 O OE1 . GLN A 1 165 ? 25.386 -19.635 9.872 1.00 78.81 ? 165 GLN A OE1 165 GLN A OE1 1 ATOM 1284 N NE2 . GLN A 1 165 ? 26.607 -20.797 8.382 1.00 78.81 ? 165 GLN A NE2 165 GLN A NE2 1 ATOM 1285 N N . GLY A 1 166 ? 21.265 -17.449 6.960 1.00 87.00 ? 166 GLY A N 166 GLY A N 1 ATOM 1286 C CA . GLY A 1 166 ? 20.068 -16.657 7.196 1.00 87.00 ? 166 GLY A CA 166 GLY A CA 1 ATOM 1287 C C . GLY A 1 166 ? 20.341 -15.166 7.250 1.00 87.00 ? 166 GLY A C 166 GLY A C 1 ATOM 1288 O O . GLY A 1 166 ? 21.488 -14.734 7.123 1.00 87.00 ? 166 GLY A O 166 GLY A O 1 ATOM 1289 N N . THR A 1 167 ? 19.286 -14.360 7.164 1.00 90.81 ? 167 THR A N 167 THR A N 1 ATOM 1290 C CA . THR A 1 167 ? 19.324 -12.902 7.188 1.00 90.81 ? 167 THR A CA 167 THR A CA 1 ATOM 1291 C C . THR A 1 167 ? 18.655 -12.364 8.449 1.00 90.81 ? 167 THR A C 167 THR A C 1 ATOM 1292 O O . THR A 1 167 ? 17.509 -12.709 8.746 1.00 90.81 ? 167 THR A O 167 THR A O 1 ATOM 1293 C CB . THR A 1 167 ? 18.638 -12.305 5.945 1.00 90.81 ? 167 THR A CB 167 THR A CB 1 ATOM 1294 O OG1 . THR A 1 167 ? 19.245 -12.846 4.765 1.00 90.81 ? 167 THR A OG1 167 THR A OG1 1 ATOM 1295 C CG2 . THR A 1 167 ? 18.771 -10.786 5.920 1.00 90.81 ? 167 THR A CG2 167 THR A CG2 1 ATOM 1296 N N . THR A 1 168 ? 19.430 -11.577 9.244 1.00 92.69 ? 168 THR A N 168 THR A N 1 ATOM 1297 C CA . THR A 1 168 ? 18.903 -10.923 10.437 1.00 92.69 ? 168 THR A CA 168 THR A CA 1 ATOM 1298 C C . THR A 1 168 ? 18.833 -9.412 10.238 1.00 92.69 ? 168 THR A C 168 THR A C 1 ATOM 1299 O O . THR A 1 168 ? 19.792 -8.797 9.769 1.00 92.69 ? 168 THR A O 168 THR A O 1 ATOM 1300 C CB . THR A 1 168 ? 19.763 -11.241 11.675 1.00 92.69 ? 168 THR A CB 168 THR A CB 1 ATOM 1301 O OG1 . THR A 1 168 ? 19.824 -12.662 11.854 1.00 92.69 ? 168 THR A OG1 168 THR A OG1 1 ATOM 1302 C CG2 . THR A 1 168 ? 19.174 -10.607 12.931 1.00 92.69 ? 168 THR A CG2 168 THR A CG2 1 ATOM 1303 N N . LEU A 1 169 ? 17.599 -8.861 10.466 1.00 91.65 ? 169 LEU A N 169 LEU A N 1 ATOM 1304 C CA . LEU A 1 169 ? 17.397 -7.418 10.393 1.00 91.65 ? 169 LEU A CA 169 LEU A CA 1 ATOM 1305 C C . LEU A 1 169 ? 16.970 -6.860 11.747 1.00 91.65 ? 169 LEU A C 169 LEU A C 1 ATOM 1306 O O . LEU A 1 169 ? 16.359 -7.568 12.550 1.00 91.65 ? 169 LEU A O 169 LEU A O 1 ATOM 1307 C CB . LEU A 1 169 ? 16.347 -7.077 9.333 1.00 91.65 ? 169 LEU A CB 169 LEU A CB 1 ATOM 1308 C CG . LEU A 1 169 ? 16.661 -7.516 7.902 1.00 91.65 ? 169 LEU A CG 169 LEU A CG 1 ATOM 1309 C CD1 . LEU A 1 169 ? 15.492 -7.190 6.979 1.00 91.65 ? 169 LEU A CD1 169 LEU A CD1 1 ATOM 1310 C CD2 . LEU A 1 169 ? 17.941 -6.850 7.407 1.00 91.65 ? 169 LEU A CD2 169 LEU A CD2 1 ATOM 1311 N N . GLY A 1 170 ? 17.361 -5.594 12.021 1.00 88.68 ? 170 GLY A N 170 GLY A N 1 ATOM 1312 C CA . GLY A 1 170 ? 16.947 -4.918 13.240 1.00 88.68 ? 170 GLY A CA 170 GLY A CA 1 ATOM 1313 C C . GLY A 1 170 ? 17.696 -5.394 14.470 1.00 88.68 ? 170 GLY A C 170 GLY A C 1 ATOM 1314 O O . GLY A 1 170 ? 18.766 -5.995 14.358 1.00 88.68 ? 170 GLY A O 170 GLY A O 1 ATOM 1315 N N . GLY A 1 171 ? 17.224 -4.956 15.664 1.00 86.79 ? 171 GLY A N 171 GLY A N 1 ATOM 1316 C CA . GLY A 1 171 ? 17.822 -5.300 16.944 1.00 86.79 ? 171 GLY A CA 171 GLY A CA 1 ATOM 1317 C C . GLY A 1 171 ? 16.799 -5.509 18.044 1.00 86.79 ? 171 GLY A C 171 GLY A C 1 ATOM 1318 O O . GLY A 1 171 ? 15.595 -5.375 17.813 1.00 86.79 ? 171 GLY A O 171 GLY A O 1 ATOM 1319 N N . PRO A 1 172 ? 17.305 -5.991 19.201 1.00 85.44 ? 172 PRO A N 172 PRO A N 1 ATOM 1320 C CA . PRO A 1 172 ? 16.417 -6.311 20.321 1.00 85.44 ? 172 PRO A CA 172 PRO A CA 1 ATOM 1321 C C . PRO A 1 172 ? 15.841 -5.067 20.992 1.00 85.44 ? 172 PRO A C 172 PRO A C 1 ATOM 1322 O O . PRO A 1 172 ? 16.071 -4.840 22.183 1.00 85.44 ? 172 PRO A O 172 PRO A O 1 ATOM 1323 C CB . PRO A 1 172 ? 17.326 -7.079 21.284 1.00 85.44 ? 172 PRO A CB 172 PRO A CB 1 ATOM 1324 C CG . PRO A 1 172 ? 18.691 -6.514 21.053 1.00 85.44 ? 172 PRO A CG 172 PRO A CG 1 ATOM 1325 C CD . PRO A 1 172 ? 18.803 -6.114 19.610 1.00 85.44 ? 172 PRO A CD 172 PRO A CD 1 ATOM 1326 N N . PHE A 1 173 ? 15.281 -4.143 20.157 1.00 83.66 ? 173 PHE A N 173 PHE A N 1 ATOM 1327 C CA . PHE A 1 173 ? 14.568 -2.988 20.688 1.00 83.66 ? 173 PHE A CA 173 PHE A CA 1 ATOM 1328 C C . PHE A 1 173 ? 13.254 -2.774 19.945 1.00 83.66 ? 173 PHE A C 173 PHE A C 1 ATOM 1329 O O . PHE A 1 173 ? 13.063 -3.301 18.847 1.00 83.66 ? 173 PHE A O 173 PHE A O 1 ATOM 1330 C CB . PHE A 1 173 ? 15.435 -1.728 20.593 1.00 83.66 ? 173 PHE A CB 173 PHE A CB 1 ATOM 1331 C CG . PHE A 1 173 ? 15.884 -1.405 19.194 1.00 83.66 ? 173 PHE A CG 173 PHE A CG 1 ATOM 1332 C CD1 . PHE A 1 173 ? 17.071 -1.925 18.692 1.00 83.66 ? 173 PHE A CD1 173 PHE A CD1 1 ATOM 1333 C CD2 . PHE A 1 173 ? 15.120 -0.579 18.380 1.00 83.66 ? 173 PHE A CD2 173 PHE A CD2 1 ATOM 1334 C CE1 . PHE A 1 173 ? 17.489 -1.628 17.397 1.00 83.66 ? 173 PHE A CE1 173 PHE A CE1 1 ATOM 1335 C CE2 . PHE A 1 173 ? 15.531 -0.277 17.085 1.00 83.66 ? 173 PHE A CE2 173 PHE A CE2 1 ATOM 1336 C CZ . PHE A 1 173 ? 16.717 -0.802 16.596 1.00 83.66 ? 173 PHE A CZ 173 PHE A CZ 1 ATOM 1337 N N . PHE A 1 174 ? 12.283 -2.181 20.591 1.00 83.03 ? 174 PHE A N 174 PHE A N 1 ATOM 1338 C CA . PHE A 1 174 ? 11.002 -1.876 19.967 1.00 83.03 ? 174 PHE A CA 174 PHE A CA 1 ATOM 1339 C C . PHE A 1 174 ? 11.134 -0.698 19.008 1.00 83.03 ? 174 PHE A C 174 PHE A C 1 ATOM 1340 O O . PHE A 1 174 ? 11.614 0.371 19.392 1.00 83.03 ? 174 PHE A O 174 PHE A O 1 ATOM 1341 C CB . PHE A 1 174 ? 9.943 -1.570 21.031 1.00 83.03 ? 174 PHE A CB 174 PHE A CB 1 ATOM 1342 C CG . PHE A 1 174 ? 9.719 -2.696 22.004 1.00 83.03 ? 174 PHE A CG 174 PHE A CG 1 ATOM 1343 C CD1 . PHE A 1 174 ? 9.362 -3.962 21.555 1.00 83.03 ? 174 PHE A CD1 174 PHE A CD1 1 ATOM 1344 C CD2 . PHE A 1 174 ? 9.865 -2.488 23.370 1.00 83.03 ? 174 PHE A CD2 174 PHE A CD2 1 ATOM 1345 C CE1 . PHE A 1 174 ? 9.154 -5.005 22.454 1.00 83.03 ? 174 PHE A CE1 174 PHE A CE1 1 ATOM 1346 C CE2 . PHE A 1 174 ? 9.658 -3.526 24.274 1.00 83.03 ? 174 PHE A CE2 174 PHE A CE2 1 ATOM 1347 C CZ . PHE A 1 174 ? 9.302 -4.783 23.814 1.00 83.03 ? 174 PHE A CZ 174 PHE A CZ 1 ATOM 1348 N N . PRO A 1 175 ? 10.984 -0.946 17.652 1.00 70.84 ? 175 PRO A N 175 PRO A N 1 ATOM 1349 C CA . PRO A 1 175 ? 11.112 0.142 16.680 1.00 70.84 ? 175 PRO A CA 175 PRO A CA 1 ATOM 1350 C C . PRO A 1 175 ? 10.178 1.312 16.978 1.00 70.84 ? 175 PRO A C 175 PRO A C 1 ATOM 1351 O O . PRO A 1 175 ? 9.198 1.154 17.712 1.00 70.84 ? 175 PRO A O 175 PRO A O 1 ATOM 1352 C CB . PRO A 1 175 ? 10.744 -0.526 15.353 1.00 70.84 ? 175 PRO A CB 175 PRO A CB 1 ATOM 1353 C CG . PRO A 1 175 ? 10.046 -1.789 15.741 1.00 70.84 ? 175 PRO A CG 175 PRO A CG 1 ATOM 1354 C CD . PRO A 1 175 ? 10.378 -2.096 17.173 1.00 70.84 ? 175 PRO A CD 175 PRO A CD 1 ATOM 1355 N N . MET B 2 1 ? -14.974 8.034 -19.199 1.00 42.89 ? 1 MET B N 1 MET B N 1 ATOM 1356 C CA . MET B 2 1 ? -15.525 9.375 -19.021 1.00 42.89 ? 1 MET B CA 1 MET B CA 1 ATOM 1357 C C . MET B 2 1 ? -14.649 10.204 -18.087 1.00 42.89 ? 1 MET B C 1 MET B C 1 ATOM 1358 O O . MET B 2 1 ? -14.394 9.803 -16.950 1.00 42.89 ? 1 MET B O 1 MET B O 1 ATOM 1359 C CB . MET B 2 1 ? -16.951 9.302 -18.473 1.00 42.89 ? 1 MET B CB 1 MET B CB 1 ATOM 1360 C CG . MET B 2 1 ? -18.022 9.265 -19.552 1.00 42.89 ? 1 MET B CG 1 MET B CG 1 ATOM 1361 S SD . MET B 2 1 ? -19.479 10.298 -19.133 1.00 42.89 ? 1 MET B SD 1 MET B SD 1 ATOM 1362 C CE . MET B 2 1 ? -20.618 9.018 -18.536 1.00 42.89 ? 1 MET B CE 1 MET B CE 1 ATOM 1363 N N . ALA B 2 2 ? -13.592 11.039 -18.619 1.00 34.46 ? 2 ALA B N 2 ALA B N 1 ATOM 1364 C CA . ALA B 2 2 ? -12.524 12.005 -18.376 1.00 34.46 ? 2 ALA B CA 2 ALA B CA 1 ATOM 1365 C C . ALA B 2 2 ? -13.028 13.186 -17.552 1.00 34.46 ? 2 ALA B C 2 ALA B C 1 ATOM 1366 O O . ALA B 2 2 ? -14.109 13.718 -17.814 1.00 34.46 ? 2 ALA B O 2 ALA B O 1 ATOM 1367 C CB . ALA B 2 2 ? -11.939 12.494 -19.699 1.00 34.46 ? 2 ALA B CB 2 ALA B CB 1 ATOM 1368 N N . LEU B 2 3 ? -13.472 13.231 -16.243 1.00 39.88 ? 3 LEU B N 3 LEU B N 1 ATOM 1369 C CA . LEU B 2 3 ? -13.612 14.559 -15.658 1.00 39.88 ? 3 LEU B CA 3 LEU B CA 1 ATOM 1370 C C . LEU B 2 3 ? -13.214 15.639 -16.658 1.00 39.88 ? 3 LEU B C 3 LEU B C 1 ATOM 1371 O O . LEU B 2 3 ? -12.165 15.541 -17.299 1.00 39.88 ? 3 LEU B O 3 LEU B O 1 ATOM 1372 C CB . LEU B 2 3 ? -12.758 14.680 -14.392 1.00 39.88 ? 3 LEU B CB 3 LEU B CB 1 ATOM 1373 C CG . LEU B 2 3 ? -13.514 14.677 -13.062 1.00 39.88 ? 3 LEU B CG 3 LEU B CG 1 ATOM 1374 C CD1 . LEU B 2 3 ? -12.961 13.594 -12.142 1.00 39.88 ? 3 LEU B CD1 3 LEU B CD1 1 ATOM 1375 C CD2 . LEU B 2 3 ? -13.430 16.046 -12.396 1.00 39.88 ? 3 LEU B CD2 3 LEU B CD2 1 ATOM 1376 N N . ALA B 2 4 ? -14.025 15.972 -17.593 1.00 44.03 ? 4 ALA B N 4 ALA B N 1 ATOM 1377 C CA . ALA B 2 4 ? -13.984 17.101 -18.519 1.00 44.03 ? 4 ALA B CA 4 ALA B CA 1 ATOM 1378 C C . ALA B 2 4 ? -13.047 18.192 -18.012 1.00 44.03 ? 4 ALA B C 4 ALA B C 1 ATOM 1379 O O . ALA B 2 4 ? -13.424 18.995 -17.155 1.00 44.03 ? 4 ALA B O 4 ALA B O 1 ATOM 1380 C CB . ALA B 2 4 ? -15.387 17.665 -18.732 1.00 44.03 ? 4 ALA B CB 4 ALA B CB 1 ATOM 1381 N N . ILE B 2 5 ? -11.826 17.845 -17.447 1.00 50.84 ? 5 ILE B N 5 ILE B N 1 ATOM 1382 C CA . ILE B 2 5 ? -10.855 18.920 -17.277 1.00 50.84 ? 5 ILE B CA 5 ILE B CA 1 ATOM 1383 C C . ILE B 2 5 ? -10.538 19.549 -18.632 1.00 50.84 ? 5 ILE B C 5 ILE B C 1 ATOM 1384 O O . ILE B 2 5 ? -10.417 18.844 -19.637 1.00 50.84 ? 5 ILE B O 5 ILE B O 1 ATOM 1385 C CB . ILE B 2 5 ? -9.560 18.411 -16.605 1.00 50.84 ? 5 ILE B CB 5 ILE B CB 1 ATOM 1386 C CG1 . ILE B 2 5 ? -9.882 17.736 -15.268 1.00 50.84 ? 5 ILE B CG1 5 ILE B CG1 1 ATOM 1387 C CG2 . ILE B 2 5 ? -8.564 19.559 -16.414 1.00 50.84 ? 5 ILE B CG2 5 ILE B CG2 1 ATOM 1388 C CD1 . ILE B 2 5 ? -8.731 16.921 -14.693 1.00 50.84 ? 5 ILE B CD1 5 ILE B CD1 1 ATOM 1389 N N . SER B 2 6 ? -11.060 20.680 -18.897 1.00 60.28 ? 6 SER B N 6 SER B N 1 ATOM 1390 C CA . SER B 2 6 ? -10.660 21.410 -20.096 1.00 60.28 ? 6 SER B CA 6 SER B CA 1 ATOM 1391 C C . SER B 2 6 ? -9.236 21.054 -20.510 1.00 60.28 ? 6 SER B C 6 SER B C 1 ATOM 1392 O O . SER B 2 6 ? -8.400 20.730 -19.663 1.00 60.28 ? 6 SER B O 6 SER B O 1 ATOM 1393 C CB . SER B 2 6 ? -10.772 22.918 -19.869 1.00 60.28 ? 6 SER B CB 6 SER B CB 1 ATOM 1394 O OG . SER B 2 6 ? -9.619 23.415 -19.212 1.00 60.28 ? 6 SER B OG 6 SER B OG 1 ATOM 1395 N N . HIS B 2 7 ? -9.047 20.617 -21.733 1.00 66.02 ? 7 HIS B N 7 HIS B N 1 ATOM 1396 C CA . HIS B 2 7 ? -7.753 20.323 -22.340 1.00 66.02 ? 7 HIS B CA 7 HIS B CA 1 ATOM 1397 C C . HIS B 2 7 ? -6.679 21.283 -21.840 1.00 66.02 ? 7 HIS B C 7 HIS B C 1 ATOM 1398 O O . HIS B 2 7 ? -5.553 20.868 -21.555 1.00 66.02 ? 7 HIS B O 7 HIS B O 1 ATOM 1399 C CB . HIS B 2 7 ? -7.850 20.390 -23.865 1.00 66.02 ? 7 HIS B CB 7 HIS B CB 1 ATOM 1400 C CG . HIS B 2 7 ? -6.638 19.864 -24.566 1.00 66.02 ? 7 HIS B CG 7 HIS B CG 1 ATOM 1401 N ND1 . HIS B 2 7 ? -6.210 18.560 -24.437 1.00 66.02 ? 7 HIS B ND1 7 HIS B ND1 1 ATOM 1402 C CD2 . HIS B 2 7 ? -5.764 20.468 -25.406 1.00 66.02 ? 7 HIS B CD2 7 HIS B CD2 1 ATOM 1403 C CE1 . HIS B 2 7 ? -5.123 18.385 -25.169 1.00 66.02 ? 7 HIS B CE1 7 HIS B CE1 1 ATOM 1404 N NE2 . HIS B 2 7 ? -4.831 19.528 -25.767 1.00 66.02 ? 7 HIS B NE2 7 HIS B NE2 1 ATOM 1405 N N . GLU B 2 8 ? -7.038 22.578 -21.640 1.00 68.83 ? 8 GLU B N 8 GLU B N 1 ATOM 1406 C CA . GLU B 2 8 ? -6.098 23.593 -21.173 1.00 68.83 ? 8 GLU B CA 8 GLU B CA 1 ATOM 1407 C C . GLU B 2 8 ? -5.658 23.319 -19.738 1.00 68.83 ? 8 GLU B C 8 GLU B C 1 ATOM 1408 O O . GLU B 2 8 ? -4.477 23.450 -19.409 1.00 68.83 ? 8 GLU B O 8 GLU B O 1 ATOM 1409 C CB . GLU B 2 8 ? -6.720 24.988 -21.274 1.00 68.83 ? 8 GLU B CB 8 GLU B CB 1 ATOM 1410 C CG . GLU B 2 8 ? -6.862 25.496 -22.702 1.00 68.83 ? 8 GLU B CG 8 GLU B CG 1 ATOM 1411 C CD . GLU B 2 8 ? -7.499 26.873 -22.789 1.00 68.83 ? 8 GLU B CD 8 GLU B CD 1 ATOM 1412 O OE1 . GLU B 2 8 ? -7.691 27.384 -23.916 1.00 68.83 ? 8 GLU B OE1 8 GLU B OE1 1 ATOM 1413 O OE2 . GLU B 2 8 ? -7.809 27.447 -21.721 1.00 68.83 ? 8 GLU B OE2 8 GLU B OE2 1 ATOM 1414 N N . ASP B 2 9 ? -6.602 22.958 -18.917 1.00 65.42 ? 9 ASP B N 9 ASP B N 1 ATOM 1415 C CA . ASP B 2 9 ? -6.325 22.670 -17.513 1.00 65.42 ? 9 ASP B CA 9 ASP B CA 1 ATOM 1416 C C . ASP B 2 9 ? -5.481 21.406 -17.369 1.00 65.42 ? 9 ASP B C 9 ASP B C 1 ATOM 1417 O O . ASP B 2 9 ? -4.605 21.334 -16.504 1.00 65.42 ? 9 ASP B O 9 ASP B O 1 ATOM 1418 C CB . ASP B 2 9 ? -7.630 22.523 -16.728 1.00 65.42 ? 9 ASP B CB 9 ASP B CB 1 ATOM 1419 C CG . ASP B 2 9 ? -8.312 23.853 -16.457 1.00 65.42 ? 9 ASP B CG 9 ASP B CG 1 ATOM 1420 O OD1 . ASP B 2 9 ? -7.690 24.914 -16.678 1.00 65.42 ? 9 ASP B OD1 9 ASP B OD1 1 ATOM 1421 O OD2 . ASP B 2 9 ? -9.481 23.839 -16.015 1.00 65.42 ? 9 ASP B OD2 9 ASP B OD2 1 ATOM 1422 N N . THR B 2 10 ? -5.736 20.457 -18.238 1.00 65.02 ? 10 THR B N 10 THR B N 1 ATOM 1423 C CA . THR B 2 10 ? -4.958 19.224 -18.225 1.00 65.02 ? 10 THR B CA 10 THR B CA 1 ATOM 1424 C C . THR B 2 10 ? -3.486 19.509 -18.511 1.00 65.02 ? 10 THR B C 10 THR B C 1 ATOM 1425 O O . THR B 2 10 ? -2.602 18.948 -17.862 1.00 65.02 ? 10 THR B O 10 THR B O 1 ATOM 1426 C CB . THR B 2 10 ? -5.497 18.213 -19.254 1.00 65.02 ? 10 THR B CB 10 THR B CB 1 ATOM 1427 O OG1 . THR B 2 10 ? -6.911 18.068 -19.078 1.00 65.02 ? 10 THR B OG1 10 THR B OG1 1 ATOM 1428 C CG2 . THR B 2 10 ? -4.833 16.850 -19.086 1.00 65.02 ? 10 THR B CG2 10 THR B CG2 1 ATOM 1429 N N . GLN B 2 11 ? -3.292 20.387 -19.470 1.00 67.83 ? 11 GLN B N 11 GLN B N 1 ATOM 1430 C CA . GLN B 2 11 ? -1.928 20.739 -19.848 1.00 67.83 ? 11 GLN B CA 11 GLN B CA 1 ATOM 1431 C C . GLN B 2 11 ? -1.209 21.457 -18.709 1.00 67.83 ? 11 GLN B C 11 GLN B C 1 ATOM 1432 O O . GLN B 2 11 ? -0.033 21.195 -18.447 1.00 67.83 ? 11 GLN B O 11 GLN B O 1 ATOM 1433 C CB . GLN B 2 11 ? -1.926 21.613 -21.104 1.00 67.83 ? 11 GLN B CB 11 GLN B CB 1 ATOM 1434 C CG . GLN B 2 11 ? -2.278 20.858 -22.379 1.00 67.83 ? 11 GLN B CG 11 GLN B CG 1 ATOM 1435 C CD . GLN B 2 11 ? -1.250 19.802 -22.738 1.00 67.83 ? 11 GLN B CD 11 GLN B CD 1 ATOM 1436 O OE1 . GLN B 2 11 ? -0.099 19.860 -22.293 1.00 67.83 ? 11 GLN B OE1 11 GLN B OE1 1 ATOM 1437 N NE2 . GLN B 2 11 ? -1.657 18.829 -23.546 1.00 67.83 ? 11 GLN B NE2 11 GLN B NE2 1 ATOM 1438 N N . ILE B 2 12 ? -1.958 22.347 -18.112 1.00 70.52 ? 12 ILE B N 12 ILE B N 1 ATOM 1439 C CA . ILE B 2 12 ? -1.376 23.092 -17.002 1.00 70.52 ? 12 ILE B CA 12 ILE B CA 1 ATOM 1440 C C . ILE B 2 12 ? -1.065 22.142 -15.848 1.00 70.52 ? 12 ILE B C 12 ILE B C 1 ATOM 1441 O O . ILE B 2 12 ? 0.022 22.193 -15.268 1.00 70.52 ? 12 ILE B O 12 ILE B O 1 ATOM 1442 C CB . ILE B 2 12 ? -2.314 24.224 -16.526 1.00 70.52 ? 12 ILE B CB 12 ILE B CB 1 ATOM 1443 C CG1 . ILE B 2 12 ? -2.463 25.289 -17.619 1.00 70.52 ? 12 ILE B CG1 12 ILE B CG1 1 ATOM 1444 C CG2 . ILE B 2 12 ? -1.797 24.844 -15.225 1.00 70.52 ? 12 ILE B CG2 12 ILE B CG2 1 ATOM 1445 C CD1 . ILE B 2 12 ? -3.538 26.328 -17.329 1.00 70.52 ? 12 ILE B CD1 12 ILE B CD1 1 ATOM 1446 N N . LEU B 2 13 ? -1.954 21.284 -15.624 1.00 66.30 ? 13 LEU B N 13 LEU B N 1 ATOM 1447 C CA . LEU B 2 13 ? -1.833 20.387 -14.481 1.00 66.30 ? 13 LEU B CA 13 LEU B CA 1 ATOM 1448 C C . LEU B 2 13 ? -0.775 19.319 -14.738 1.00 66.30 ? 13 LEU B C 13 LEU B C 1 ATOM 1449 O O . LEU B 2 13 ? 0.006 18.984 -13.844 1.00 66.30 ? 13 LEU B O 13 LEU B O 1 ATOM 1450 C CB . LEU B 2 13 ? -3.179 19.724 -14.173 1.00 66.30 ? 13 LEU B CB 13 LEU B CB 1 ATOM 1451 C CG . LEU B 2 13 ? -4.259 20.629 -13.577 1.00 66.30 ? 13 LEU B CG 13 LEU B CG 1 ATOM 1452 C CD1 . LEU B 2 13 ? -5.595 19.896 -13.526 1.00 66.30 ? 13 LEU B CD1 13 LEU B CD1 1 ATOM 1453 C CD2 . LEU B 2 13 ? -3.851 21.105 -12.187 1.00 66.30 ? 13 LEU B CD2 13 LEU B CD2 1 ATOM 1454 N N . LEU B 2 14 ? -0.721 18.770 -15.968 1.00 66.47 ? 14 LEU B N 14 LEU B N 1 ATOM 1455 C CA . LEU B 2 14 ? 0.167 17.661 -16.298 1.00 66.47 ? 14 LEU B CA 14 LEU B CA 1 ATOM 1456 C C . LEU B 2 14 ? 1.566 18.167 -16.637 1.00 66.47 ? 14 LEU B C 14 LEU B C 1 ATOM 1457 O O . LEU B 2 14 ? 2.563 17.547 -16.260 1.00 66.47 ? 14 LEU B O 14 LEU B O 1 ATOM 1458 C CB . LEU B 2 14 ? -0.395 16.855 -17.473 1.00 66.47 ? 14 LEU B CB 14 LEU B CB 1 ATOM 1459 C CG . LEU B 2 14 ? -1.625 15.995 -17.178 1.00 66.47 ? 14 LEU B CG 14 LEU B CG 1 ATOM 1460 C CD1 . LEU B 2 14 ? -2.195 15.424 -18.472 1.00 66.47 ? 14 LEU B CD1 14 LEU B CD1 1 ATOM 1461 C CD2 . LEU B 2 14 ? -1.274 14.877 -16.202 1.00 66.47 ? 14 LEU B CD2 14 LEU B CD2 1 ATOM 1462 N N . LYS B 2 15 ? 1.621 19.343 -17.210 1.00 71.46 ? 15 LYS B N 15 LYS B N 1 ATOM 1463 C CA . LYS B 2 15 ? 2.929 19.756 -17.709 1.00 71.46 ? 15 LYS B CA 15 LYS B CA 1 ATOM 1464 C C . LYS B 2 15 ? 3.561 20.803 -16.795 1.00 71.46 ? 15 LYS B C 15 LYS B C 1 ATOM 1465 O O . LYS B 2 15 ? 4.737 20.695 -16.440 1.00 71.46 ? 15 LYS B O 15 LYS B O 1 ATOM 1466 C CB . LYS B 2 15 ? 2.813 20.305 -19.132 1.00 71.46 ? 15 LYS B CB 15 LYS B CB 1 ATOM 1467 C CG . LYS B 2 15 ? 2.591 19.236 -20.192 1.00 71.46 ? 15 LYS B CG 15 LYS B CG 1 ATOM 1468 C CD . LYS B 2 15 ? 2.670 19.818 -21.597 1.00 71.46 ? 15 LYS B CD 15 LYS B CD 1 ATOM 1469 C CE . LYS B 2 15 ? 2.476 18.744 -22.659 1.00 71.46 ? 15 LYS B CE 15 LYS B CE 1 ATOM 1470 N NZ . LYS B 2 15 ? 2.570 19.306 -24.040 1.00 71.46 ? 15 LYS B NZ 15 LYS B NZ 1 ATOM 1471 N N . ASP B 2 16 ? 2.794 21.801 -16.347 1.00 71.28 ? 16 ASP B N 16 ASP B N 1 ATOM 1472 C CA . ASP B 2 16 ? 3.377 22.960 -15.678 1.00 71.28 ? 16 ASP B CA 16 ASP B CA 1 ATOM 1473 C C . ASP B 2 16 ? 3.505 22.720 -14.175 1.00 71.28 ? 16 ASP B C 16 ASP B C 1 ATOM 1474 O O . ASP B 2 16 ? 4.522 23.065 -13.570 1.00 71.28 ? 16 ASP B O 16 ASP B O 1 ATOM 1475 C CB . ASP B 2 16 ? 2.537 24.211 -15.941 1.00 71.28 ? 16 ASP B CB 16 ASP B CB 1 ATOM 1476 C CG . ASP B 2 16 ? 2.639 24.703 -17.374 1.00 71.28 ? 16 ASP B CG 16 ASP B CG 1 ATOM 1477 O OD1 . ASP B 2 16 ? 3.552 24.264 -18.107 1.00 71.28 ? 16 ASP B OD1 16 ASP B OD1 1 ATOM 1478 O OD2 . ASP B 2 16 ? 1.800 25.539 -17.774 1.00 71.28 ? 16 ASP B OD2 16 ASP B OD2 1 ATOM 1479 N N . LYS B 2 17 ? 2.546 22.064 -13.591 1.00 74.99 ? 17 LYS B N 17 LYS B N 1 ATOM 1480 C CA . LYS B 2 17 ? 2.512 21.969 -12.135 1.00 74.99 ? 17 LYS B CA 17 LYS B CA 1 ATOM 1481 C C . LYS B 2 17 ? 3.252 20.726 -11.648 1.00 74.99 ? 17 LYS B C 17 LYS B C 1 ATOM 1482 O O . LYS B 2 17 ? 3.553 20.603 -10.459 1.00 74.99 ? 17 LYS B O 17 LYS B O 1 ATOM 1483 C CB . LYS B 2 17 ? 1.068 21.951 -11.631 1.00 74.99 ? 17 LYS B CB 17 LYS B CB 1 ATOM 1484 C CG . LYS B 2 17 ? 0.352 23.287 -11.755 1.00 74.99 ? 17 LYS B CG 17 LYS B CG 1 ATOM 1485 C CD . LYS B 2 17 ? -0.877 23.349 -10.857 1.00 74.99 ? 17 LYS B CD 17 LYS B CD 1 ATOM 1486 C CE . LYS B 2 17 ? -1.546 24.715 -10.916 1.00 74.99 ? 17 LYS B CE 17 LYS B CE 1 ATOM 1487 N NZ . LYS B 2 17 ? -2.712 24.801 -9.987 1.00 74.99 ? 17 LYS B NZ 17 LYS B NZ 1 ATOM 1488 N N . ASN B 2 18 ? 3.621 19.826 -12.546 1.00 76.67 ? 18 ASN B N 18 ASN B N 1 ATOM 1489 C CA . ASN B 2 18 ? 4.315 18.600 -12.164 1.00 76.67 ? 18 ASN B CA 18 ASN B CA 1 ATOM 1490 C C . ASN B 2 18 ? 5.826 18.740 -12.317 1.00 76.67 ? 18 ASN B C 18 ASN B C 1 ATOM 1491 O O . ASN B 2 18 ? 6.560 17.757 -12.201 1.00 76.67 ? 18 ASN B O 18 ASN B O 1 ATOM 1492 C CB . ASN B 2 18 ? 3.805 17.416 -12.988 1.00 76.67 ? 18 ASN B CB 18 ASN B CB 1 ATOM 1493 C CG . ASN B 2 18 ? 2.442 16.932 -12.534 1.00 76.67 ? 18 ASN B CG 18 ASN B CG 1 ATOM 1494 O OD1 . ASN B 2 18 ? 2.116 16.983 -11.345 1.00 76.67 ? 18 ASN B OD1 18 ASN B OD1 1 ATOM 1495 N ND2 . ASN B 2 18 ? 1.636 16.459 -13.477 1.00 76.67 ? 18 ASN B ND2 18 ASN B ND2 1 ATOM 1496 N N . ILE B 2 19 ? 6.256 20.018 -12.568 1.00 82.10 ? 19 ILE B N 19 ILE B N 1 ATOM 1497 C CA . ILE B 2 19 ? 7.687 20.287 -12.652 1.00 82.10 ? 19 ILE B CA 19 ILE B CA 1 ATOM 1498 C C . ILE B 2 19 ? 8.244 20.563 -11.257 1.00 82.10 ? 19 ILE B C 19 ILE B C 1 ATOM 1499 O O . ILE B 2 19 ? 7.677 21.357 -10.502 1.00 82.10 ? 19 ILE B O 19 ILE B O 1 ATOM 1500 C CB . ILE B 2 19 ? 7.985 21.475 -13.593 1.00 82.10 ? 19 ILE B CB 19 ILE B CB 1 ATOM 1501 C CG1 . ILE B 2 19 ? 7.461 21.183 -15.004 1.00 82.10 ? 19 ILE B CG1 19 ILE B CG1 1 ATOM 1502 C CG2 . ILE B 2 19 ? 9.485 21.782 -13.618 1.00 82.10 ? 19 ILE B CG2 19 ILE B CG2 1 ATOM 1503 C CD1 . ILE B 2 19 ? 7.454 22.396 -15.925 1.00 82.10 ? 19 ILE B CD1 19 ILE B CD1 1 ATOM 1504 N N . LEU B 2 20 ? 9.272 19.829 -10.914 1.00 85.16 ? 20 LEU B N 20 LEU B N 1 ATOM 1505 C CA . LEU B 2 20 ? 9.875 19.959 -9.592 1.00 85.16 ? 20 LEU B CA 20 LEU B CA 1 ATOM 1506 C C . LEU B 2 20 ? 10.629 21.279 -9.466 1.00 85.16 ? 20 LEU B C 20 LEU B C 1 ATOM 1507 O O . LEU B 2 20 ? 11.618 21.502 -10.167 1.00 85.16 ? 20 LEU B O 20 LEU B O 1 ATOM 1508 C CB . LEU B 2 20 ? 10.822 18.788 -9.316 1.00 85.16 ? 20 LEU B CB 20 LEU B CB 1 ATOM 1509 C CG . LEU B 2 20 ? 11.248 18.589 -7.861 1.00 85.16 ? 20 LEU B CG 20 LEU B CG 1 ATOM 1510 C CD1 . LEU B 2 20 ? 10.060 18.141 -7.017 1.00 85.16 ? 20 LEU B CD1 20 LEU B CD1 1 ATOM 1511 C CD2 . LEU B 2 20 ? 12.386 17.578 -7.771 1.00 85.16 ? 20 LEU B CD2 20 LEU B CD2 1 ATOM 1512 N N . GLN B 2 21 ? 10.063 22.207 -8.710 1.00 86.72 ? 21 GLN B N 21 GLN B N 1 ATOM 1513 C CA . GLN B 2 21 ? 10.665 23.468 -8.289 1.00 86.72 ? 21 GLN B CA 21 GLN B CA 1 ATOM 1514 C C . GLN B 2 21 ? 10.864 23.505 -6.777 1.00 86.72 ? 21 GLN B C 21 GLN B C 1 ATOM 1515 O O . GLN B 2 21 ? 10.339 22.655 -6.055 1.00 86.72 ? 21 GLN B O 21 GLN B O 1 ATOM 1516 C CB . GLN B 2 21 ? 9.803 24.650 -8.735 1.00 86.72 ? 21 GLN B CB 21 GLN B CB 1 ATOM 1517 C CG . GLN B 2 21 ? 9.618 24.742 -10.243 1.00 86.72 ? 21 GLN B CG 21 GLN B CG 1 ATOM 1518 C CD . GLN B 2 21 ? 8.687 25.868 -10.653 1.00 86.72 ? 21 GLN B CD 21 GLN B CD 1 ATOM 1519 O OE1 . GLN B 2 21 ? 7.951 26.415 -9.825 1.00 86.72 ? 21 GLN B OE1 21 GLN B OE1 1 ATOM 1520 N NE2 . GLN B 2 21 ? 8.712 26.221 -11.933 1.00 86.72 ? 21 GLN B NE2 21 GLN B NE2 1 ATOM 1521 N N . GLU B 2 22 ? 11.582 24.452 -6.367 1.00 86.44 ? 22 GLU B N 22 GLU B N 1 ATOM 1522 C CA . GLU B 2 22 ? 11.880 24.546 -4.942 1.00 86.44 ? 22 GLU B CA 22 GLU B CA 1 ATOM 1523 C C . GLU B 2 22 ? 10.604 24.696 -4.119 1.00 86.44 ? 22 GLU B C 22 GLU B C 1 ATOM 1524 O O . GLU B 2 22 ? 10.480 24.107 -3.043 1.00 86.44 ? 22 GLU B O 22 GLU B O 1 ATOM 1525 C CB . GLU B 2 22 ? 12.824 25.719 -4.666 1.00 86.44 ? 22 GLU B CB 22 GLU B CB 1 ATOM 1526 C CG . GLU B 2 22 ? 13.341 25.771 -3.236 1.00 86.44 ? 22 GLU B CG 22 GLU B CG 1 ATOM 1527 C CD . GLU B 2 22 ? 14.467 26.773 -3.040 1.00 86.44 ? 22 GLU B CD 22 GLU B CD 1 ATOM 1528 O OE1 . GLU B 2 22 ? 15.022 26.852 -1.920 1.00 86.44 ? 22 GLU B OE1 22 GLU B OE1 1 ATOM 1529 O OE2 . GLU B 2 22 ? 14.796 27.487 -4.013 1.00 86.44 ? 22 GLU B OE2 22 GLU B OE2 1 ATOM 1530 N N . SER B 2 23 ? 9.639 25.473 -4.606 1.00 86.75 ? 23 SER B N 23 SER B N 1 ATOM 1531 C CA . SER B 2 23 ? 8.380 25.669 -3.896 1.00 86.75 ? 23 SER B CA 23 SER B CA 1 ATOM 1532 C C . SER B 2 23 ? 7.586 24.370 -3.808 1.00 86.75 ? 23 SER B C 23 SER B C 1 ATOM 1533 O O . SER B 2 23 ? 6.967 24.082 -2.782 1.00 86.75 ? 23 SER B O 23 SER B O 1 ATOM 1534 C CB . SER B 2 23 ? 7.538 26.745 -4.584 1.00 86.75 ? 23 SER B CB 23 SER B CB 1 ATOM 1535 O OG . SER B 2 23 ? 7.209 26.356 -5.907 1.00 86.75 ? 23 SER B OG 23 SER B OG 1 ATOM 1536 N N . VAL B 2 24 ? 7.603 23.607 -4.899 1.00 88.91 ? 24 VAL B N 24 VAL B N 1 ATOM 1537 C CA . VAL B 2 24 ? 6.909 22.324 -4.950 1.00 88.91 ? 24 VAL B CA 24 VAL B CA 1 ATOM 1538 C C . VAL B 2 24 ? 7.605 21.323 -4.031 1.00 88.91 ? 24 VAL B C 24 VAL B C 1 ATOM 1539 O O . VAL B 2 24 ? 6.946 20.579 -3.301 1.00 88.91 ? 24 VAL B O 24 VAL B O 1 ATOM 1540 C CB . VAL B 2 24 ? 6.846 21.770 -6.391 1.00 88.91 ? 24 VAL B CB 24 VAL B CB 1 ATOM 1541 C CG1 . VAL B 2 24 ? 6.241 20.368 -6.405 1.00 88.91 ? 24 VAL B CG1 24 VAL B CG1 1 ATOM 1542 C CG2 . VAL B 2 24 ? 6.044 22.711 -7.289 1.00 88.91 ? 24 VAL B CG2 24 VAL B CG2 1 ATOM 1543 N N . LEU B 2 25 ? 8.934 21.326 -4.073 1.00 90.63 ? 25 LEU B N 25 LEU B N 1 ATOM 1544 C CA . LEU B 2 25 ? 9.728 20.448 -3.221 1.00 90.63 ? 25 LEU B CA 25 LEU B CA 1 ATOM 1545 C C . LEU B 2 25 ? 9.403 20.679 -1.749 1.00 90.63 ? 25 LEU B C 25 LEU B C 1 ATOM 1546 O O . LEU B 2 25 ? 9.299 19.726 -0.974 1.00 90.63 ? 25 LEU B O 25 LEU B O 1 ATOM 1547 C CB . LEU B 2 25 ? 11.222 20.670 -3.467 1.00 90.63 ? 25 LEU B CB 25 LEU B CB 1 ATOM 1548 C CG . LEU B 2 25 ? 12.180 19.769 -2.684 1.00 90.63 ? 25 LEU B CG 25 LEU B CG 1 ATOM 1549 C CD1 . LEU B 2 25 ? 11.971 18.309 -3.074 1.00 90.63 ? 25 LEU B CD1 25 LEU B CD1 1 ATOM 1550 C CD2 . LEU B 2 25 ? 13.626 20.190 -2.923 1.00 90.63 ? 25 LEU B CD2 25 LEU B CD2 1 ATOM 1551 N N . ASN B 2 26 ? 9.218 21.925 -1.363 1.00 90.58 ? 26 ASN B N 26 ASN B N 1 ATOM 1552 C CA . ASN B 2 26 ? 8.888 22.265 0.018 1.00 90.58 ? 26 ASN B CA 26 ASN B CA 1 ATOM 1553 C C . ASN B 2 26 ? 7.537 21.688 0.429 1.00 90.58 ? 26 ASN B C 26 ASN B C 1 ATOM 1554 O O . ASN B 2 26 ? 7.364 21.254 1.570 1.00 90.58 ? 26 ASN B O 26 ASN B O 1 ATOM 1555 C CB . ASN B 2 26 ? 8.899 23.782 0.214 1.00 90.58 ? 26 ASN B CB 26 ASN B CB 1 ATOM 1556 C CG . ASN B 2 26 ? 10.302 24.351 0.291 1.00 90.58 ? 26 ASN B CG 26 ASN B CG 1 ATOM 1557 O OD1 . ASN B 2 26 ? 11.262 23.631 0.578 1.00 90.58 ? 26 ASN B OD1 26 ASN B OD1 1 ATOM 1558 N ND2 . ASN B 2 26 ? 10.432 25.647 0.033 1.00 90.58 ? 26 ASN B ND2 26 ASN B ND2 1 ATOM 1559 N N . LYS B 2 27 ? 6.632 21.693 -0.465 1.00 91.06 ? 27 LYS B N 27 LYS B N 1 ATOM 1560 C CA . LYS B 2 27 ? 5.315 21.122 -0.198 1.00 91.06 ? 27 LYS B CA 27 LYS B CA 1 ATOM 1561 C C . LYS B 2 27 ? 5.405 19.616 0.027 1.00 91.06 ? 27 LYS B C 27 LYS B C 1 ATOM 1562 O O . LYS B 2 27 ? 4.776 19.081 0.942 1.00 91.06 ? 27 LYS B O 27 LYS B O 1 ATOM 1563 C CB . LYS B 2 27 ? 4.355 21.424 -1.349 1.00 91.06 ? 27 LYS B CB 27 LYS B CB 1 ATOM 1564 C CG . LYS B 2 27 ? 3.996 22.897 -1.486 1.00 91.06 ? 27 LYS B CG 27 LYS B CG 1 ATOM 1565 C CD . LYS B 2 27 ? 3.042 23.134 -2.649 1.00 91.06 ? 27 LYS B CD 27 LYS B CD 1 ATOM 1566 C CE . LYS B 2 27 ? 2.684 24.607 -2.788 1.00 91.06 ? 27 LYS B CE 27 LYS B CE 1 ATOM 1567 N NZ . LYS B 2 27 ? 1.813 24.856 -3.976 1.00 91.06 ? 27 LYS B NZ 27 LYS B NZ 1 ATOM 1568 N N . TYR B 2 28 ? 6.188 18.892 -0.815 1.00 92.35 ? 28 TYR B N 28 TYR B N 1 ATOM 1569 C CA . TYR B 2 28 ? 6.426 17.467 -0.613 1.00 92.35 ? 28 TYR B CA 28 TYR B CA 1 ATOM 1570 C C . TYR B 2 28 ? 7.117 17.213 0.721 1.00 92.35 ? 28 TYR B C 28 TYR B C 1 ATOM 1571 O O . TYR B 2 28 ? 6.752 16.288 1.450 1.00 92.35 ? 28 TYR B O 28 TYR B O 1 ATOM 1572 C CB . TYR B 2 28 ? 7.270 16.896 -1.756 1.00 92.35 ? 28 TYR B CB 28 TYR B CB 1 ATOM 1573 C CG . TYR B 2 28 ? 6.464 16.509 -2.972 1.00 92.35 ? 28 TYR B CG 28 TYR B CG 1 ATOM 1574 C CD1 . TYR B 2 28 ? 5.501 15.505 -2.903 1.00 92.35 ? 28 TYR B CD1 28 TYR B CD1 1 ATOM 1575 C CD2 . TYR B 2 28 ? 6.663 17.146 -4.192 1.00 92.35 ? 28 TYR B CD2 28 TYR B CD2 1 ATOM 1576 C CE1 . TYR B 2 28 ? 4.757 15.143 -4.021 1.00 92.35 ? 28 TYR B CE1 28 TYR B CE1 1 ATOM 1577 C CE2 . TYR B 2 28 ? 5.924 16.793 -5.317 1.00 92.35 ? 28 TYR B CE2 28 TYR B CE2 1 ATOM 1578 C CZ . TYR B 2 28 ? 4.975 15.792 -5.221 1.00 92.35 ? 28 TYR B CZ 28 TYR B CZ 1 ATOM 1579 O OH . TYR B 2 28 ? 4.241 15.439 -6.332 1.00 92.35 ? 28 TYR B OH 28 TYR B OH 1 ATOM 1580 N N . ARG B 2 29 ? 8.079 18.070 1.006 1.00 92.36 ? 29 ARG B N 29 ARG B N 1 ATOM 1581 C CA . ARG B 2 29 ? 8.848 17.927 2.238 1.00 92.36 ? 29 ARG B CA 29 ARG B CA 1 ATOM 1582 C C . ARG B 2 29 ? 7.951 18.068 3.463 1.00 92.36 ? 29 ARG B C 29 ARG B C 1 ATOM 1583 O O . ARG B 2 29 ? 8.046 17.276 4.403 1.00 92.36 ? 29 ARG B O 29 ARG B O 1 ATOM 1584 C CB . ARG B 2 29 ? 9.975 18.960 2.292 1.00 92.36 ? 29 ARG B CB 29 ARG B CB 1 ATOM 1585 C CG . ARG B 2 29 ? 11.201 18.578 1.478 1.00 92.36 ? 29 ARG B CG 29 ARG B CG 1 ATOM 1586 C CD . ARG B 2 29 ? 12.341 19.567 1.676 1.00 92.36 ? 29 ARG B CD 29 ARG B CD 1 ATOM 1587 N NE . ARG B 2 29 ? 13.408 19.363 0.701 1.00 92.36 ? 29 ARG B NE 29 ARG B NE 1 ATOM 1588 C CZ . ARG B 2 29 ? 14.301 20.284 0.350 1.00 92.36 ? 29 ARG B CZ 29 ARG B CZ 1 ATOM 1589 N NH1 . ARG B 2 29 ? 14.273 21.496 0.891 1.00 92.36 ? 29 ARG B NH1 29 ARG B NH1 1 ATOM 1590 N NH2 . ARG B 2 29 ? 15.230 19.991 -0.548 1.00 92.36 ? 29 ARG B NH2 29 ARG B NH2 1 ATOM 1591 N N . THR B 2 30 ? 7.132 19.072 3.394 1.00 91.72 ? 30 THR B N 30 THR B N 1 ATOM 1592 C CA . THR B 2 30 ? 6.227 19.314 4.513 1.00 91.72 ? 30 THR B CA 30 THR B CA 1 ATOM 1593 C C . THR B 2 30 ? 5.251 18.152 4.679 1.00 91.72 ? 30 THR B C 30 THR B C 1 ATOM 1594 O O . THR B 2 30 ? 5.000 17.701 5.799 1.00 91.72 ? 30 THR B O 30 THR B O 1 ATOM 1595 C CB . THR B 2 30 ? 5.440 20.624 4.322 1.00 91.72 ? 30 THR B CB 30 THR B CB 1 ATOM 1596 O OG1 . THR B 2 30 ? 6.363 21.711 4.179 1.00 91.72 ? 30 THR B OG1 30 THR B OG1 1 ATOM 1597 C CG2 . THR B 2 30 ? 4.531 20.898 5.516 1.00 91.72 ? 30 THR B CG2 30 THR B CG2 1 ATOM 1598 N N . ALA B 2 31 ? 4.677 17.737 3.557 1.00 92.92 ? 31 ALA B N 31 ALA B N 1 ATOM 1599 C CA . ALA B 2 31 ? 3.770 16.593 3.599 1.00 92.92 ? 31 ALA B CA 31 ALA B CA 1 ATOM 1600 C C . ALA B 2 31 ? 4.470 15.359 4.163 1.00 92.92 ? 31 ALA B C 31 ALA B C 1 ATOM 1601 O O . ALA B 2 31 ? 3.901 14.637 4.985 1.00 92.92 ? 31 ALA B O 31 ALA B O 1 ATOM 1602 C CB . ALA B 2 31 ? 3.220 16.299 2.206 1.00 92.92 ? 31 ALA B CB 31 ALA B CB 1 ATOM 1603 N N . GLY B 2 32 ? 5.709 15.128 3.727 1.00 93.88 ? 32 GLY B N 32 GLY B N 1 ATOM 1604 C CA . GLY B 2 32 ? 6.505 14.019 4.231 1.00 93.88 ? 32 GLY B CA 32 GLY B CA 1 ATOM 1605 C C . GLY B 2 32 ? 6.834 14.143 5.707 1.00 93.88 ? 32 GLY B C 32 GLY B C 1 ATOM 1606 O O . GLY B 2 32 ? 6.778 13.158 6.445 1.00 93.88 ? 32 GLY B O 32 GLY B O 1 ATOM 1607 N N . GLN B 2 33 ? 7.155 15.307 6.171 1.00 93.65 ? 33 GLN B N 33 GLN B N 1 ATOM 1608 C CA . GLN B 2 33 ? 7.495 15.554 7.569 1.00 93.65 ? 33 GLN B CA 33 GLN B CA 1 ATOM 1609 C C . GLN B 2 33 ? 6.318 15.236 8.486 1.00 93.65 ? 33 GLN B C 33 GLN B C 1 ATOM 1610 O O . GLN B 2 33 ? 6.491 14.608 9.532 1.00 93.65 ? 33 GLN B O 33 GLN B O 1 ATOM 1611 C CB . GLN B 2 33 ? 7.937 17.005 7.765 1.00 93.65 ? 33 GLN B CB 33 GLN B CB 1 ATOM 1612 C CG . GLN B 2 33 ? 9.355 17.286 7.288 1.00 93.65 ? 33 GLN B CG 33 GLN B CG 1 ATOM 1613 C CD . GLN B 2 33 ? 9.767 18.732 7.491 1.00 93.65 ? 33 GLN B CD 33 GLN B CD 1 ATOM 1614 O OE1 . GLN B 2 33 ? 8.936 19.590 7.806 1.00 93.65 ? 33 GLN B OE1 33 GLN B OE1 1 ATOM 1615 N NE2 . GLN B 2 33 ? 11.053 19.014 7.311 1.00 93.65 ? 33 GLN B NE2 33 GLN B NE2 1 ATOM 1616 N N . ILE B 2 34 ? 5.123 15.650 8.124 1.00 93.96 ? 34 ILE B N 34 ILE B N 1 ATOM 1617 C CA . ILE B 2 34 ? 3.917 15.407 8.909 1.00 93.96 ? 34 ILE B CA 34 ILE B CA 1 ATOM 1618 C C . ILE B 2 34 ? 3.601 13.913 8.919 1.00 93.96 ? 34 ILE B C 34 ILE B C 1 ATOM 1619 O O . ILE B 2 34 ? 3.253 13.352 9.961 1.00 93.96 ? 34 ILE B O 34 ILE B O 1 ATOM 1620 C CB . ILE B 2 34 ? 2.714 16.205 8.360 1.00 93.96 ? 34 ILE B CB 34 ILE B CB 1 ATOM 1621 C CG1 . ILE B 2 34 ? 2.963 17.711 8.505 1.00 93.96 ? 34 ILE B CG1 34 ILE B CG1 1 ATOM 1622 C CG2 . ILE B 2 34 ? 1.422 15.793 9.072 1.00 93.96 ? 34 ILE B CG2 34 ILE B CG2 1 ATOM 1623 C CD1 . ILE B 2 34 ? 1.908 18.580 7.832 1.00 93.96 ? 34 ILE B CD1 34 ILE B CD1 1 ATOM 1624 N N . ALA B 2 35 ? 3.715 13.313 7.739 1.00 95.01 ? 35 ALA B N 35 ALA B N 1 ATOM 1625 C CA . ALA B 2 35 ? 3.446 11.881 7.638 1.00 95.01 ? 35 ALA B CA 35 ALA B CA 1 ATOM 1626 C C . ALA B 2 35 ? 4.391 11.081 8.530 1.00 95.01 ? 35 ALA B C 35 ALA B C 1 ATOM 1627 O O . ALA B 2 35 ? 3.961 10.167 9.238 1.00 95.01 ? 35 ALA B O 35 ALA B O 1 ATOM 1628 C CB . ALA B 2 35 ? 3.569 11.418 6.188 1.00 95.01 ? 35 ALA B CB 35 ALA B CB 1 ATOM 1629 N N . GLN B 2 36 ? 5.672 11.407 8.568 1.00 94.50 ? 36 GLN B N 36 GLN B N 1 ATOM 1630 C CA . GLN B 2 36 ? 6.672 10.722 9.379 1.00 94.50 ? 36 GLN B CA 36 GLN B CA 1 ATOM 1631 C C . GLN B 2 36 ? 6.427 10.955 10.867 1.00 94.50 ? 36 GLN B C 36 GLN B C 1 ATOM 1632 O O . GLN B 2 36 ? 6.597 10.043 11.680 1.00 94.50 ? 36 GLN B O 36 GLN B O 1 ATOM 1633 C CB . GLN B 2 36 ? 8.080 11.185 9.000 1.00 94.50 ? 36 GLN B CB 36 GLN B CB 1 ATOM 1634 C CG . GLN B 2 36 ? 8.565 10.646 7.661 1.00 94.50 ? 36 GLN B CG 36 GLN B CG 1 ATOM 1635 C CD . GLN B 2 36 ? 10.050 10.867 7.442 1.00 94.50 ? 36 GLN B CD 36 GLN B CD 1 ATOM 1636 O OE1 . GLN B 2 36 ? 10.814 11.032 8.398 1.00 94.50 ? 36 GLN B OE1 36 GLN B OE1 1 ATOM 1637 N NE2 . GLN B 2 36 ? 10.469 10.872 6.181 1.00 94.50 ? 36 GLN B NE2 36 GLN B NE2 1 ATOM 1638 N N . THR B 2 37 ? 6.050 12.184 11.159 1.00 94.57 ? 37 THR B N 37 THR B N 1 ATOM 1639 C CA . THR B 2 37 ? 5.738 12.510 12.546 1.00 94.57 ? 37 THR B CA 37 THR B CA 1 ATOM 1640 C C . THR B 2 37 ? 4.536 11.707 13.034 1.00 94.57 ? 37 THR B C 37 THR B C 1 ATOM 1641 O O . THR B 2 37 ? 4.528 11.216 14.165 1.00 94.57 ? 37 THR B O 37 THR B O 1 ATOM 1642 C CB . THR B 2 37 ? 5.457 14.015 12.716 1.00 94.57 ? 37 THR B CB 37 THR B CB 1 ATOM 1643 O OG1 . THR B 2 37 ? 6.580 14.762 12.235 1.00 94.57 ? 37 THR B OG1 37 THR B OG1 1 ATOM 1644 C CG2 . THR B 2 37 ? 5.216 14.367 14.181 1.00 94.57 ? 37 THR B CG2 37 THR B CG2 1 ATOM 1645 N N . ALA B 2 38 ? 3.590 11.602 12.183 1.00 95.18 ? 38 ALA B N 38 ALA B N 1 ATOM 1646 C CA . ALA B 2 38 ? 2.392 10.834 12.512 1.00 95.18 ? 38 ALA B CA 38 ALA B CA 1 ATOM 1647 C C . ALA B 2 38 ? 2.718 9.351 12.669 1.00 95.18 ? 38 ALA B C 38 ALA B C 1 ATOM 1648 O O . ALA B 2 38 ? 2.188 8.684 13.561 1.00 95.18 ? 38 ALA B O 38 ALA B O 1 ATOM 1649 C CB . ALA B 2 38 ? 1.323 11.030 11.440 1.00 95.18 ? 38 ALA B CB 38 ALA B CB 1 ATOM 1650 N N . LEU B 2 39 ? 3.543 8.826 11.784 1.00 95.70 ? 39 LEU B N 39 LEU B N 1 ATOM 1651 C CA . LEU B 2 39 ? 3.961 7.432 11.883 1.00 95.70 ? 39 LEU B CA 39 LEU B CA 1 ATOM 1652 C C . LEU B 2 39 ? 4.680 7.173 13.203 1.00 95.70 ? 39 LEU B C 39 LEU B C 1 ATOM 1653 O O . LEU B 2 39 ? 4.433 6.159 13.860 1.00 95.70 ? 39 LEU B O 39 LEU B O 1 ATOM 1654 C CB . LEU B 2 39 ? 4.873 7.061 10.711 1.00 95.70 ? 39 LEU B CB 39 LEU B CB 1 ATOM 1655 C CG . LEU B 2 39 ? 5.363 5.613 10.665 1.00 95.70 ? 39 LEU B CG 39 LEU B CG 1 ATOM 1656 C CD1 . LEU B 2 39 ? 4.179 4.656 10.572 1.00 95.70 ? 39 LEU B CD1 39 LEU B CD1 1 ATOM 1657 C CD2 . LEU B 2 39 ? 6.317 5.408 9.493 1.00 95.70 ? 39 LEU B CD2 39 LEU B CD2 1 ATOM 1658 N N . LYS B 2 40 ? 5.530 8.050 13.606 1.00 94.75 ? 40 LYS B N 40 LYS B N 1 ATOM 1659 C CA . LYS B 2 40 ? 6.223 7.932 14.885 1.00 94.75 ? 40 LYS B CA 40 LYS B CA 1 ATOM 1660 C C . LYS B 2 40 ? 5.237 7.960 16.049 1.00 94.75 ? 40 LYS B C 40 LYS B C 1 ATOM 1661 O O . LYS B 2 40 ? 5.403 7.228 17.028 1.00 94.75 ? 40 LYS B O 40 LYS B O 1 ATOM 1662 C CB . LYS B 2 40 ? 7.252 9.053 15.043 1.00 94.75 ? 40 LYS B CB 40 LYS B CB 1 ATOM 1663 C CG . LYS B 2 40 ? 8.212 8.853 16.207 1.00 94.75 ? 40 LYS B CG 40 LYS B CG 1 ATOM 1664 C CD . LYS B 2 40 ? 9.294 9.924 16.229 1.00 94.75 ? 40 LYS B CD 40 LYS B CD 1 ATOM 1665 C CE . LYS B 2 40 ? 10.222 9.758 17.425 1.00 94.75 ? 40 LYS B CE 40 LYS B CE 1 ATOM 1666 N NZ . LYS B 2 40 ? 11.316 10.775 17.423 1.00 94.75 ? 40 LYS B NZ 40 LYS B NZ 1 ATOM 1667 N N . TYR B 2 41 ? 4.292 8.804 15.914 1.00 94.95 ? 41 TYR B N 41 TYR B N 1 ATOM 1668 C CA . TYR B 2 41 ? 3.261 8.940 16.938 1.00 94.95 ? 41 TYR B CA 41 TYR B CA 1 ATOM 1669 C C . TYR B 2 41 ? 2.509 7.629 17.132 1.00 94.95 ? 41 TYR B C 41 TYR B C 1 ATOM 1670 O O . TYR B 2 41 ? 2.365 7.149 18.259 1.00 94.95 ? 41 TYR B O 41 TYR B O 1 ATOM 1671 C CB . TYR B 2 41 ? 2.280 10.056 16.567 1.00 94.95 ? 41 TYR B CB 41 TYR B CB 1 ATOM 1672 C CG . TYR B 2 41 ? 1.117 10.182 17.521 1.00 94.95 ? 41 TYR B CG 41 TYR B CG 1 ATOM 1673 C CD1 . TYR B 2 41 ? -0.168 9.803 17.139 1.00 94.95 ? 41 TYR B CD1 41 TYR B CD1 1 ATOM 1674 C CD2 . TYR B 2 41 ? 1.300 10.683 18.806 1.00 94.95 ? 41 TYR B CD2 41 TYR B CD2 1 ATOM 1675 C CE1 . TYR B 2 41 ? -1.243 9.920 18.013 1.00 94.95 ? 41 TYR B CE1 41 TYR B CE1 1 ATOM 1676 C CE2 . TYR B 2 41 ? 0.232 10.804 19.689 1.00 94.95 ? 41 TYR B CE2 41 TYR B CE2 1 ATOM 1677 C CZ . TYR B 2 41 ? -1.033 10.420 19.285 1.00 94.95 ? 41 TYR B CZ 41 TYR B CZ 1 ATOM 1678 O OH . TYR B 2 41 ? -2.094 10.538 20.155 1.00 94.95 ? 41 TYR B OH 41 TYR B OH 1 ATOM 1679 N N . VAL B 2 42 ? 2.011 7.043 16.070 1.00 95.17 ? 42 VAL B N 42 VAL B N 1 ATOM 1680 C CA . VAL B 2 42 ? 1.209 5.827 16.162 1.00 95.17 ? 42 VAL B CA 42 VAL B CA 1 ATOM 1681 C C . VAL B 2 42 ? 2.089 4.660 16.607 1.00 95.17 ? 42 VAL B C 42 VAL B C 1 ATOM 1682 O O . VAL B 2 42 ? 1.660 3.819 17.401 1.00 95.17 ? 42 VAL B O 42 VAL B O 1 ATOM 1683 C CB . VAL B 2 42 ? 0.525 5.495 14.816 1.00 95.17 ? 42 VAL B CB 42 VAL B CB 1 ATOM 1684 C CG1 . VAL B 2 42 ? 1.562 5.098 13.767 1.00 95.17 ? 42 VAL B CG1 42 VAL B CG1 1 ATOM 1685 C CG2 . VAL B 2 42 ? -0.505 4.383 15.002 1.00 95.17 ? 42 VAL B CG2 42 VAL B CG2 1 ATOM 1686 N N . THR B 2 43 ? 3.308 4.593 16.073 1.00 94.78 ? 43 THR B N 43 THR B N 1 ATOM 1687 C CA . THR B 2 43 ? 4.234 3.549 16.497 1.00 94.78 ? 43 THR B CA 43 THR B CA 1 ATOM 1688 C C . THR B 2 43 ? 4.504 3.642 17.996 1.00 94.78 ? 43 THR B C 43 THR B C 1 ATOM 1689 O O . THR B 2 43 ? 4.593 2.620 18.680 1.00 94.78 ? 43 THR B O 43 THR B O 1 ATOM 1690 C CB . THR B 2 43 ? 5.565 3.636 15.727 1.00 94.78 ? 43 THR B CB 43 THR B CB 1 ATOM 1691 O OG1 . THR B 2 43 ? 6.103 4.957 15.863 1.00 94.78 ? 43 THR B OG1 43 THR B OG1 1 ATOM 1692 C CG2 . THR B 2 43 ? 5.365 3.332 14.246 1.00 94.78 ? 43 THR B CG2 43 THR B CG2 1 ATOM 1693 N N . SER B 2 44 ? 4.655 4.854 18.477 1.00 93.76 ? 44 SER B N 44 SER B N 1 ATOM 1694 C CA . SER B 2 44 ? 4.858 5.073 19.905 1.00 93.76 ? 44 SER B CA 44 SER B CA 1 ATOM 1695 C C . SER B 2 44 ? 3.643 4.628 20.712 1.00 93.76 ? 44 SER B C 44 SER B C 1 ATOM 1696 O O . SER B 2 44 ? 3.786 4.028 21.779 1.00 93.76 ? 44 SER B O 44 SER B O 1 ATOM 1697 C CB . SER B 2 44 ? 5.154 6.547 20.185 1.00 93.76 ? 44 SER B CB 44 SER B CB 1 ATOM 1698 O OG . SER B 2 44 ? 5.279 6.780 21.578 1.00 93.76 ? 44 SER B OG 44 SER B OG 1 ATOM 1699 N N . LEU B 2 45 ? 2.483 4.929 20.235 1.00 93.26 ? 45 LEU B N 45 LEU B N 1 ATOM 1700 C CA . LEU B 2 45 ? 1.257 4.504 20.902 1.00 93.26 ? 45 LEU B CA 45 LEU B CA 1 ATOM 1701 C C . LEU B 2 45 ? 1.173 2.983 20.969 1.00 93.26 ? 45 LEU B C 45 LEU B C 1 ATOM 1702 O O . LEU B 2 45 ? 0.787 2.423 21.998 1.00 93.26 ? 45 LEU B O 45 LEU B O 1 ATOM 1703 C CB . LEU B 2 45 ? 0.030 5.063 20.175 1.00 93.26 ? 45 LEU B CB 45 LEU B CB 1 ATOM 1704 C CG . LEU B 2 45 ? -0.231 6.561 20.339 1.00 93.26 ? 45 LEU B CG 45 LEU B CG 1 ATOM 1705 C CD1 . LEU B 2 45 ? -1.434 6.983 19.502 1.00 93.26 ? 45 LEU B CD1 45 LEU B CD1 1 ATOM 1706 C CD2 . LEU B 2 45 ? -0.446 6.908 21.808 1.00 93.26 ? 45 LEU B CD2 45 LEU B CD2 1 ATOM 1707 N N . ILE B 2 46 ? 1.547 2.337 19.897 1.00 94.25 ? 46 ILE B N 46 ILE B N 1 ATOM 1708 C CA . ILE B 2 46 ? 1.510 0.880 19.847 1.00 94.25 ? 46 ILE B CA 46 ILE B CA 1 ATOM 1709 C C . ILE B 2 46 ? 2.535 0.304 20.822 1.00 94.25 ? 46 ILE B C 46 ILE B C 1 ATOM 1710 O O . ILE B 2 46 ? 2.230 -0.621 21.579 1.00 94.25 ? 46 ILE B O 46 ILE B O 1 ATOM 1711 C CB . ILE B 2 46 ? 1.776 0.356 18.418 1.00 94.25 ? 46 ILE B CB 46 ILE B CB 1 ATOM 1712 C CG1 . ILE B 2 46 ? 0.615 0.727 17.489 1.00 94.25 ? 46 ILE B CG1 46 ILE B CG1 1 ATOM 1713 C CG2 . ILE B 2 46 ? 2.004 -1.158 18.432 1.00 94.25 ? 46 ILE B CG2 46 ILE B CG2 1 ATOM 1714 C CD1 . ILE B 2 46 ? 0.860 0.386 16.025 1.00 94.25 ? 46 ILE B CD1 46 ILE B CD1 1 ATOM 1715 N N . ASN B 2 47 ? 3.711 0.871 20.786 1.00 92.59 ? 47 ASN B N 47 ASN B N 1 ATOM 1716 C CA . ASN B 2 47 ? 4.753 0.412 21.699 1.00 92.59 ? 47 ASN B CA 47 ASN B CA 1 ATOM 1717 C C . ASN B 2 47 ? 4.340 0.595 23.157 1.00 92.59 ? 47 ASN B C 47 ASN B C 1 ATOM 1718 O O . ASN B 2 47 ? 4.553 -0.295 23.982 1.00 92.59 ? 47 ASN B O 47 ASN B O 1 ATOM 1719 C CB . ASN B 2 47 ? 6.068 1.144 21.424 1.00 92.59 ? 47 ASN B CB 47 ASN B CB 1 ATOM 1720 C CG . ASN B 2 47 ? 6.767 0.640 20.177 1.00 92.59 ? 47 ASN B CG 47 ASN B CG 1 ATOM 1721 O OD1 . ASN B 2 47 ? 6.563 -0.501 19.754 1.00 92.59 ? 47 ASN B OD1 47 ASN B OD1 1 ATOM 1722 N ND2 . ASN B 2 47 ? 7.597 1.486 19.578 1.00 92.59 ? 47 ASN B ND2 47 ASN B ND2 1 ATOM 1723 N N . ASP B 2 48 ? 3.739 1.732 23.469 1.00 91.57 ? 48 ASP B N 48 ASP B N 1 ATOM 1724 C CA . ASP B 2 48 ? 3.316 2.034 24.833 1.00 91.57 ? 48 ASP B CA 48 ASP B CA 1 ATOM 1725 C C . ASP B 2 48 ? 2.182 1.111 25.274 1.00 91.57 ? 48 ASP B C 48 ASP B C 1 ATOM 1726 O O . ASP B 2 48 ? 2.160 0.648 26.416 1.00 91.57 ? 48 ASP B O 48 ASP B O 1 ATOM 1727 C CB . ASP B 2 48 ? 2.878 3.496 24.948 1.00 91.57 ? 48 ASP B CB 48 ASP B CB 1 ATOM 1728 C CG . ASP B 2 48 ? 4.037 4.472 24.844 1.00 91.57 ? 48 ASP B CG 48 ASP B CG 1 ATOM 1729 O OD1 . ASP B 2 48 ? 5.207 4.041 24.932 1.00 91.57 ? 48 ASP B OD1 48 ASP B OD1 1 ATOM 1730 O OD2 . ASP B 2 48 ? 3.778 5.683 24.674 1.00 91.57 ? 48 ASP B OD2 48 ASP B OD2 1 ATOM 1731 N N . SER B 2 49 ? 1.299 0.772 24.365 1.00 91.33 ? 49 SER B N 49 SER B N 1 ATOM 1732 C CA . SER B 2 49 ? 0.096 0.016 24.696 1.00 91.33 ? 49 SER B CA 49 SER B CA 1 ATOM 1733 C C . SER B 2 49 ? 0.368 -1.485 24.696 1.00 91.33 ? 49 SER B C 49 SER B C 1 ATOM 1734 O O . SER B 2 49 ? -0.130 -2.211 25.558 1.00 91.33 ? 49 SER B O 49 SER B O 1 ATOM 1735 C CB . SER B 2 49 ? -1.029 0.338 23.711 1.00 91.33 ? 49 SER B CB 49 SER B CB 1 ATOM 1736 O OG . SER B 2 49 ? -1.465 1.678 23.867 1.00 91.33 ? 49 SER B OG 49 SER B OG 1 ATOM 1737 N N . TYR B 2 50 ? 1.248 -1.998 23.788 1.00 91.18 ? 50 TYR B N 50 TYR B N 1 ATOM 1738 C CA . TYR B 2 50 ? 1.351 -3.438 23.583 1.00 91.18 ? 50 TYR B CA 50 TYR B CA 1 ATOM 1739 C C . TYR B 2 50 ? 2.720 -3.953 24.009 1.00 91.18 ? 50 TYR B C 50 TYR B C 1 ATOM 1740 O O . TYR B 2 50 ? 2.855 -5.104 24.429 1.00 91.18 ? 50 TYR B O 50 TYR B O 1 ATOM 1741 C CB . TYR B 2 50 ? 1.093 -3.792 22.115 1.00 91.18 ? 50 TYR B CB 50 TYR B CB 1 ATOM 1742 C CG . TYR B 2 50 ? -0.343 -3.602 21.688 1.00 91.18 ? 50 TYR B CG 50 TYR B CG 1 ATOM 1743 C CD1 . TYR B 2 50 ? -1.276 -4.625 21.837 1.00 91.18 ? 50 TYR B CD1 50 TYR B CD1 1 ATOM 1744 C CD2 . TYR B 2 50 ? -0.768 -2.399 21.134 1.00 91.18 ? 50 TYR B CD2 50 TYR B CD2 1 ATOM 1745 C CE1 . TYR B 2 50 ? -2.599 -4.455 21.443 1.00 91.18 ? 50 TYR B CE1 50 TYR B CE1 1 ATOM 1746 C CE2 . TYR B 2 50 ? -2.088 -2.218 20.737 1.00 91.18 ? 50 TYR B CE2 50 TYR B CE2 1 ATOM 1747 C CZ . TYR B 2 50 ? -2.995 -3.249 20.895 1.00 91.18 ? 50 TYR B CZ 50 TYR B CZ 1 ATOM 1748 O OH . TYR B 2 50 ? -4.304 -3.075 20.504 1.00 91.18 ? 50 TYR B OH 50 TYR B OH 1 ATOM 1749 N N . HIS B 2 51 ? 3.752 -3.185 23.959 1.00 89.27 ? 51 HIS B N 51 HIS B N 1 ATOM 1750 C CA . HIS B 2 51 ? 5.085 -3.652 24.324 1.00 89.27 ? 51 HIS B CA 51 HIS B CA 1 ATOM 1751 C C . HIS B 2 51 ? 5.458 -3.206 25.734 1.00 89.27 ? 51 HIS B C 51 HIS B C 1 ATOM 1752 O O . HIS B 2 51 ? 5.747 -4.039 26.596 1.00 89.27 ? 51 HIS B O 51 HIS B O 1 ATOM 1753 C CB . HIS B 2 51 ? 6.123 -3.145 23.321 1.00 89.27 ? 51 HIS B CB 51 HIS B CB 1 ATOM 1754 C CG . HIS B 2 51 ? 6.011 -3.777 21.970 1.00 89.27 ? 51 HIS B CG 51 HIS B CG 1 ATOM 1755 N ND1 . HIS B 2 51 ? 6.459 -3.162 20.822 1.00 89.27 ? 51 HIS B ND1 51 HIS B ND1 1 ATOM 1756 C CD2 . HIS B 2 51 ? 5.503 -4.972 21.587 1.00 89.27 ? 51 HIS B CD2 51 HIS B CD2 1 ATOM 1757 C CE1 . HIS B 2 51 ? 6.230 -3.954 19.787 1.00 89.27 ? 51 HIS B CE1 51 HIS B CE1 1 ATOM 1758 N NE2 . HIS B 2 51 ? 5.651 -5.058 20.225 1.00 89.27 ? 51 HIS B NE2 51 HIS B NE2 1 ATOM 1759 N N . SER B 2 52 ? 5.366 -1.844 25.973 1.00 87.87 ? 52 SER B N 52 SER B N 1 ATOM 1760 C CA . SER B 2 52 ? 5.801 -1.303 27.257 1.00 87.87 ? 52 SER B CA 52 SER B CA 1 ATOM 1761 C C . SER B 2 52 ? 4.688 -1.385 28.297 1.00 87.87 ? 52 SER B C 52 SER B C 1 ATOM 1762 O O . SER B 2 52 ? 4.955 -1.399 29.500 1.00 87.87 ? 52 SER B O 52 SER B O 1 ATOM 1763 C CB . SER B 2 52 ? 6.258 0.148 27.100 1.00 87.87 ? 52 SER B CB 52 SER B CB 1 ATOM 1764 O OG . SER B 2 52 ? 7.337 0.239 26.187 1.00 87.87 ? 52 SER B OG 52 SER B OG 1 ATOM 1765 N N . LYS B 2 53 ? 3.470 -1.526 27.858 1.00 82.17 ? 53 LYS B N 53 LYS B N 1 ATOM 1766 C CA . LYS B 2 53 ? 2.282 -1.603 28.703 1.00 82.17 ? 53 LYS B CA 53 LYS B CA 1 ATOM 1767 C C . LYS B 2 53 ? 2.241 -0.449 29.700 1.00 82.17 ? 53 LYS B C 53 LYS B C 1 ATOM 1768 O O . LYS B 2 53 ? 1.916 -0.646 30.873 1.00 82.17 ? 53 LYS B O 53 LYS B O 1 ATOM 1769 C CB . LYS B 2 53 ? 2.237 -2.939 29.446 1.00 82.17 ? 53 LYS B CB 53 LYS B CB 1 ATOM 1770 C CG . LYS B 2 53 ? 2.100 -4.150 28.534 1.00 82.17 ? 53 LYS B CG 53 LYS B CG 1 ATOM 1771 C CD . LYS B 2 53 ? 1.953 -5.438 29.334 1.00 82.17 ? 53 LYS B CD 53 LYS B CD 1 ATOM 1772 C CE . LYS B 2 53 ? 1.842 -6.653 28.424 1.00 82.17 ? 53 LYS B CE 53 LYS B CE 1 ATOM 1773 N NZ . LYS B 2 53 ? 1.705 -7.919 29.204 1.00 82.17 ? 53 LYS B NZ 53 LYS B NZ 1 ATOM 1774 N N . THR B 2 54 ? 2.718 0.706 29.278 1.00 80.62 ? 54 THR B N 54 THR B N 1 ATOM 1775 C CA . THR B 2 54 ? 2.720 1.912 30.098 1.00 80.62 ? 54 THR B CA 54 THR B CA 1 ATOM 1776 C C . THR B 2 54 ? 1.324 2.525 30.162 1.00 80.62 ? 54 THR B C 54 THR B C 1 ATOM 1777 O O . THR B 2 54 ? 0.988 3.217 31.125 1.00 80.62 ? 54 THR B O 54 THR B O 1 ATOM 1778 C CB . THR B 2 54 ? 3.717 2.954 29.556 1.00 80.62 ? 54 THR B CB 54 THR B CB 1 ATOM 1779 O OG1 . THR B 2 54 ? 3.454 3.180 28.166 1.00 80.62 ? 54 THR B OG1 54 THR B OG1 1 ATOM 1780 C CG2 . THR B 2 54 ? 5.156 2.475 29.718 1.00 80.62 ? 54 THR B CG2 54 THR B CG2 1 ATOM 1781 N N . THR B 2 55 ? 0.555 2.241 29.207 1.00 76.84 ? 55 THR B N 55 THR B N 1 ATOM 1782 C CA . THR B 2 55 ? -0.803 2.773 29.175 1.00 76.84 ? 55 THR B CA 55 THR B CA 1 ATOM 1783 C C . THR B 2 55 ? -1.761 1.856 29.929 1.00 76.84 ? 55 THR B C 55 THR B C 1 ATOM 1784 O O . THR B 2 55 ? -1.590 0.635 29.927 1.00 76.84 ? 55 THR B O 55 THR B O 1 ATOM 1785 C CB . THR B 2 55 ? -1.297 2.958 27.728 1.00 76.84 ? 55 THR B CB 55 THR B CB 1 ATOM 1786 O OG1 . THR B 2 55 ? -0.333 3.723 26.994 1.00 76.84 ? 55 THR B OG1 55 THR B OG1 1 ATOM 1787 C CG2 . THR B 2 55 ? -2.638 3.684 27.693 1.00 76.84 ? 55 THR B CG2 55 THR B CG2 1 ATOM 1788 N N . GLN B 2 56 ? -2.669 2.480 30.686 1.00 74.78 ? 56 GLN B N 56 GLN B N 1 ATOM 1789 C CA . GLN B 2 56 ? -3.618 1.770 31.537 1.00 74.78 ? 56 GLN B CA 56 GLN B CA 1 ATOM 1790 C C . GLN B 2 56 ? -4.539 0.878 30.709 1.00 74.78 ? 56 GLN B C 56 GLN B C 1 ATOM 1791 O O . GLN B 2 56 ? -4.858 -0.241 31.116 1.00 74.78 ? 56 GLN B O 56 GLN B O 1 ATOM 1792 C CB . GLN B 2 56 ? -4.446 2.759 32.360 1.00 74.78 ? 56 GLN B CB 56 GLN B CB 1 ATOM 1793 C CG . GLN B 2 56 ? -3.677 3.396 33.510 1.00 74.78 ? 56 GLN B CG 56 GLN B CG 1 ATOM 1794 C CD . GLN B 2 56 ? -4.513 4.388 34.296 1.00 74.78 ? 56 GLN B CD 56 GLN B CD 1 ATOM 1795 O OE1 . GLN B 2 56 ? -5.681 4.629 33.974 1.00 74.78 ? 56 GLN B OE1 56 GLN B OE1 1 ATOM 1796 N NE2 . GLN B 2 56 ? -3.922 4.971 35.333 1.00 74.78 ? 56 GLN B NE2 56 GLN B NE2 1 ATOM 1797 N N . ARG B 2 57 ? -4.783 1.422 29.477 1.00 84.06 ? 57 ARG B N 57 ARG B N 1 ATOM 1798 C CA . ARG B 2 57 ? -5.731 0.718 28.621 1.00 84.06 ? 57 ARG B CA 57 ARG B CA 1 ATOM 1799 C C . ARG B 2 57 ? -5.115 0.406 27.262 1.00 84.06 ? 57 ARG B C 57 ARG B C 1 ATOM 1800 O O . ARG B 2 57 ? -4.458 1.259 26.661 1.00 84.06 ? 57 ARG B O 57 ARG B O 1 ATOM 1801 C CB . ARG B 2 57 ? -7.007 1.544 28.440 1.00 84.06 ? 57 ARG B CB 57 ARG B CB 1 ATOM 1802 C CG . ARG B 2 57 ? -8.047 0.882 27.549 1.00 84.06 ? 57 ARG B CG 57 ARG B CG 1 ATOM 1803 C CD . ARG B 2 57 ? -9.289 1.749 27.392 1.00 84.06 ? 57 ARG B CD 57 ARG B CD 1 ATOM 1804 N NE . ARG B 2 57 ? -9.111 2.763 26.357 1.00 84.06 ? 57 ARG B NE 57 ARG B NE 1 ATOM 1805 C CZ . ARG B 2 57 ? -9.976 3.004 25.375 1.00 84.06 ? 57 ARG B CZ 57 ARG B CZ 1 ATOM 1806 N NH1 . ARG B 2 57 ? -11.101 2.305 25.276 1.00 84.06 ? 57 ARG B NH1 57 ARG B NH1 1 ATOM 1807 N NH2 . ARG B 2 57 ? -9.715 3.951 24.486 1.00 84.06 ? 57 ARG B NH2 57 ARG B NH2 1 ATOM 1808 N N . GLN B 2 58 ? -5.339 -0.874 26.854 1.00 85.50 ? 58 GLN B N 58 GLN B N 1 ATOM 1809 C CA . GLN B 2 58 ? -4.893 -1.267 25.522 1.00 85.50 ? 58 GLN B CA 58 GLN B CA 1 ATOM 1810 C C . GLN B 2 58 ? -5.784 -0.661 24.441 1.00 85.50 ? 58 GLN B C 58 GLN B C 1 ATOM 1811 O O . GLN B 2 58 ? -6.987 -0.928 24.399 1.00 85.50 ? 58 GLN B O 58 GLN B O 1 ATOM 1812 C CB . GLN B 2 58 ? -4.871 -2.791 25.390 1.00 85.50 ? 58 GLN B CB 58 GLN B CB 1 ATOM 1813 C CG . GLN B 2 58 ? -3.775 -3.463 26.206 1.00 85.50 ? 58 GLN B CG 58 GLN B CG 1 ATOM 1814 C CD . GLN B 2 58 ? -3.759 -4.971 26.038 1.00 85.50 ? 58 GLN B CD 58 GLN B CD 1 ATOM 1815 O OE1 . GLN B 2 58 ? -4.698 -5.558 25.491 1.00 85.50 ? 58 GLN B OE1 58 GLN B OE1 1 ATOM 1816 N NE2 . GLN B 2 58 ? -2.693 -5.609 26.509 1.00 85.50 ? 58 GLN B NE2 58 GLN B NE2 1 ATOM 1817 N N . LEU B 2 59 ? -5.151 0.141 23.669 1.00 91.28 ? 59 LEU B N 59 LEU B N 1 ATOM 1818 C CA . LEU B 2 59 ? -5.881 0.804 22.593 1.00 91.28 ? 59 LEU B CA 59 LEU B CA 1 ATOM 1819 C C . LEU B 2 59 ? -6.168 -0.167 21.453 1.00 91.28 ? 59 LEU B C 59 LEU B C 1 ATOM 1820 O O . LEU B 2 59 ? -5.298 -0.950 21.064 1.00 91.28 ? 59 LEU B O 59 LEU B O 1 ATOM 1821 C CB . LEU B 2 59 ? -5.090 2.005 22.069 1.00 91.28 ? 59 LEU B CB 59 LEU B CB 1 ATOM 1822 C CG . LEU B 2 59 ? -4.845 3.142 23.062 1.00 91.28 ? 59 LEU B CG 59 LEU B CG 1 ATOM 1823 C CD1 . LEU B 2 59 ? -3.845 4.140 22.489 1.00 91.28 ? 59 LEU B CD1 59 LEU B CD1 1 ATOM 1824 C CD2 . LEU B 2 59 ? -6.157 3.835 23.416 1.00 91.28 ? 59 LEU B CD2 59 LEU B CD2 1 ATOM 1825 N N . THR B 2 60 ? -7.397 -0.124 20.973 1.00 92.50 ? 60 THR B N 60 THR B N 1 ATOM 1826 C CA . THR B 2 60 ? -7.789 -0.967 19.849 1.00 92.50 ? 60 THR B CA 60 THR B CA 1 ATOM 1827 C C . THR B 2 60 ? -7.348 -0.344 18.527 1.00 92.50 ? 60 THR B C 60 THR B C 1 ATOM 1828 O O . THR B 2 60 ? -6.989 0.834 18.478 1.00 92.50 ? 60 THR B O 60 THR B O 1 ATOM 1829 C CB . THR B 2 60 ? -9.312 -1.197 19.828 1.00 92.50 ? 60 THR B CB 60 THR B CB 1 ATOM 1830 O OG1 . THR B 2 60 ? -9.976 0.056 19.626 1.00 92.50 ? 60 THR B OG1 60 THR B OG1 1 ATOM 1831 C CG2 . THR B 2 60 ? -9.793 -1.810 21.139 1.00 92.50 ? 60 THR B CG2 60 THR B CG2 1 ATOM 1832 N N . VAL B 2 61 ? -7.350 -1.088 17.489 1.00 94.24 ? 61 VAL B N 61 VAL B N 1 ATOM 1833 C CA . VAL B 2 61 ? -6.886 -0.668 16.171 1.00 94.24 ? 61 VAL B CA 61 VAL B CA 1 ATOM 1834 C C . VAL B 2 61 ? -7.707 0.527 15.691 1.00 94.24 ? 61 VAL B C 61 VAL B C 1 ATOM 1835 O O . VAL B 2 61 ? -7.149 1.531 15.242 1.00 94.24 ? 61 VAL B O 61 VAL B O 1 ATOM 1836 C CB . VAL B 2 61 ? -6.971 -1.820 15.145 1.00 94.24 ? 61 VAL B CB 61 VAL B CB 1 ATOM 1837 C CG1 . VAL B 2 61 ? -6.731 -1.300 13.729 1.00 94.24 ? 61 VAL B CG1 61 VAL B CG1 1 ATOM 1838 C CG2 . VAL B 2 61 ? -5.968 -2.918 15.492 1.00 94.24 ? 61 VAL B CG2 61 VAL B CG2 1 ATOM 1839 N N . PRO B 2 62 ? -9.072 0.475 15.783 1.00 93.38 ? 62 PRO B N 62 PRO B N 1 ATOM 1840 C CA . PRO B 2 62 ? -9.848 1.641 15.355 1.00 93.38 ? 62 PRO B CA 62 PRO B CA 1 ATOM 1841 C C . PRO B 2 62 ? -9.508 2.900 16.149 1.00 93.38 ? 62 PRO B C 62 PRO B C 1 ATOM 1842 O O . PRO B 2 62 ? -9.473 3.998 15.588 1.00 93.38 ? 62 PRO B O 62 PRO B O 1 ATOM 1843 C CB . PRO B 2 62 ? -11.296 1.213 15.604 1.00 93.38 ? 62 PRO B CB 62 PRO B CB 1 ATOM 1844 C CG . PRO B 2 62 ? -11.263 -0.281 15.572 1.00 93.38 ? 62 PRO B CG 62 PRO B CG 1 ATOM 1845 C CD . PRO B 2 62 ? -9.916 -0.739 16.055 1.00 93.38 ? 62 PRO B CD 62 PRO B CD 1 ATOM 1846 N N . GLU B 2 63 ? -9.210 2.731 17.439 1.00 92.61 ? 63 GLU B N 63 GLU B N 1 ATOM 1847 C CA . GLU B 2 63 ? -8.850 3.865 18.285 1.00 92.61 ? 63 GLU B CA 63 GLU B CA 1 ATOM 1848 C C . GLU B 2 63 ? -7.500 4.451 17.878 1.00 92.61 ? 63 GLU B C 63 GLU B C 1 ATOM 1849 O O . GLU B 2 63 ? -7.337 5.672 17.831 1.00 92.61 ? 63 GLU B O 63 GLU B O 1 ATOM 1850 C CB . GLU B 2 63 ? -8.820 3.449 19.758 1.00 92.61 ? 63 GLU B CB 63 GLU B CB 1 ATOM 1851 C CG . GLU B 2 63 ? -10.197 3.191 20.352 1.00 92.61 ? 63 GLU B CG 63 GLU B CG 1 ATOM 1852 C CD . GLU B 2 63 ? -10.145 2.612 21.757 1.00 92.61 ? 63 GLU B CD 63 GLU B CD 1 ATOM 1853 O OE1 . GLU B 2 63 ? -11.200 2.555 22.429 1.00 92.61 ? 63 GLU B OE1 63 GLU B OE1 1 ATOM 1854 O OE2 . GLU B 2 63 ? -9.041 2.214 22.190 1.00 92.61 ? 63 GLU B OE2 63 GLU B OE2 1 ATOM 1855 N N . LEU B 2 64 ? -6.603 3.581 17.630 1.00 93.89 ? 64 LEU B N 64 LEU B N 1 ATOM 1856 C CA . LEU B 2 64 ? -5.281 4.014 17.191 1.00 93.89 ? 64 LEU B CA 64 LEU B CA 1 ATOM 1857 C C . LEU B 2 64 ? -5.374 4.820 15.900 1.00 93.89 ? 64 LEU B C 64 LEU B C 1 ATOM 1858 O O . LEU B 2 64 ? -4.732 5.864 15.767 1.00 93.89 ? 64 LEU B O 64 LEU B O 1 ATOM 1859 C CB . LEU B 2 64 ? -4.361 2.807 16.990 1.00 93.89 ? 64 LEU B CB 64 LEU B CB 1 ATOM 1860 C CG . LEU B 2 64 ? -3.897 2.089 18.258 1.00 93.89 ? 64 LEU B CG 64 LEU B CG 1 ATOM 1861 C CD1 . LEU B 2 64 ? -3.265 0.747 17.905 1.00 93.89 ? 64 LEU B CD1 64 LEU B CD1 1 ATOM 1862 C CD2 . LEU B 2 64 ? -2.917 2.959 19.037 1.00 93.89 ? 64 LEU B CD2 64 LEU B CD2 1 ATOM 1863 N N . CYS B 2 65 ? -6.172 4.316 14.960 1.00 94.67 ? 65 CYS B N 65 CYS B N 1 ATOM 1864 C CA . CYS B 2 65 ? -6.335 4.987 13.675 1.00 94.67 ? 65 CYS B CA 65 CYS B CA 1 ATOM 1865 C C . CYS B 2 65 ? -7.002 6.346 13.850 1.00 94.67 ? 65 CYS B C 65 CYS B C 1 ATOM 1866 O O . CYS B 2 65 ? -6.589 7.329 13.232 1.00 94.67 ? 65 CYS B O 65 CYS B O 1 ATOM 1867 C CB . CYS B 2 65 ? -7.158 4.124 12.720 1.00 94.67 ? 65 CYS B CB 65 CYS B CB 1 ATOM 1868 S SG . CYS B 2 65 ? -6.308 2.626 12.176 1.00 94.67 ? 65 CYS B SG 65 CYS B SG 1 ATOM 1869 N N . LEU B 2 66 ? -8.017 6.408 14.680 1.00 93.92 ? 66 LEU B N 66 LEU B N 1 ATOM 1870 C CA . LEU B 2 66 ? -8.747 7.644 14.939 1.00 93.92 ? 66 LEU B CA 66 LEU B CA 1 ATOM 1871 C C . LEU B 2 66 ? -7.838 8.690 15.575 1.00 93.92 ? 66 LEU B C 66 LEU B C 1 ATOM 1872 O O . LEU B 2 66 ? -7.836 9.851 15.161 1.00 93.92 ? 66 LEU B O 66 LEU B O 1 ATOM 1873 C CB . LEU B 2 66 ? -9.950 7.376 15.847 1.00 93.92 ? 66 LEU B CB 66 LEU B CB 1 ATOM 1874 C CG . LEU B 2 66 ? -10.854 8.572 16.147 1.00 93.92 ? 66 LEU B CG 66 LEU B CG 1 ATOM 1875 C CD1 . LEU B 2 66 ? -11.506 9.078 14.864 1.00 93.92 ? 66 LEU B CD1 66 LEU B CD1 1 ATOM 1876 C CD2 . LEU B 2 66 ? -11.912 8.199 17.179 1.00 93.92 ? 66 LEU B CD2 66 LEU B CD2 1 ATOM 1877 N N . LEU B 2 67 ? -7.077 8.316 16.546 1.00 93.12 ? 67 LEU B N 67 LEU B N 1 ATOM 1878 C CA . LEU B 2 67 ? -6.183 9.222 17.258 1.00 93.12 ? 67 LEU B CA 67 LEU B CA 1 ATOM 1879 C C . LEU B 2 67 ? -5.099 9.758 16.329 1.00 93.12 ? 67 LEU B C 67 LEU B C 1 ATOM 1880 O O . LEU B 2 67 ? -4.749 10.939 16.394 1.00 93.12 ? 67 LEU B O 67 LEU B O 1 ATOM 1881 C CB . LEU B 2 67 ? -5.541 8.511 18.453 1.00 93.12 ? 67 LEU B CB 67 LEU B CB 1 ATOM 1882 C CG . LEU B 2 67 ? -6.462 8.208 19.636 1.00 93.12 ? 67 LEU B CG 67 LEU B CG 1 ATOM 1883 C CD1 . LEU B 2 67 ? -5.737 7.348 20.666 1.00 93.12 ? 67 LEU B CD1 67 LEU B CD1 1 ATOM 1884 C CD2 . LEU B 2 67 ? -6.963 9.501 20.270 1.00 93.12 ? 67 LEU B CD2 67 LEU B CD2 1 ATOM 1885 N N . THR B 2 68 ? -4.603 8.863 15.534 1.00 94.57 ? 68 THR B N 68 THR B N 1 ATOM 1886 C CA . THR B 2 68 ? -3.559 9.266 14.598 1.00 94.57 ? 68 THR B CA 68 THR B CA 1 ATOM 1887 C C . THR B 2 68 ? -4.101 10.263 13.579 1.00 94.57 ? 68 THR B C 68 THR B C 1 ATOM 1888 O O . THR B 2 68 ? -3.455 11.270 13.283 1.00 94.57 ? 68 THR B O 68 THR B O 1 ATOM 1889 C CB . THR B 2 68 ? -2.966 8.048 13.865 1.00 94.57 ? 68 THR B CB 68 THR B CB 1 ATOM 1890 O OG1 . THR B 2 68 ? -2.485 7.104 14.830 1.00 94.57 ? 68 THR B OG1 68 THR B OG1 1 ATOM 1891 C CG2 . THR B 2 68 ? -1.813 8.461 12.956 1.00 94.57 ? 68 THR B CG2 68 THR B CG2 1 ATOM 1892 N N . ASP B 2 69 ? -5.262 9.978 13.024 1.00 95.15 ? 69 ASP B N 69 ASP B N 1 ATOM 1893 C CA . ASP B 2 69 ? -5.874 10.896 12.068 1.00 95.15 ? 69 ASP B CA 69 ASP B CA 1 ATOM 1894 C C . ASP B 2 69 ? -6.146 12.255 12.707 1.00 95.15 ? 69 ASP B C 69 ASP B C 1 ATOM 1895 O O . ASP B 2 69 ? -5.956 13.295 12.073 1.00 95.15 ? 69 ASP B O 69 ASP B O 1 ATOM 1896 C CB . ASP B 2 69 ? -7.173 10.306 11.514 1.00 95.15 ? 69 ASP B CB 69 ASP B CB 1 ATOM 1897 C CG . ASP B 2 69 ? -6.938 9.188 10.513 1.00 95.15 ? 69 ASP B CG 69 ASP B CG 1 ATOM 1898 O OD1 . ASP B 2 69 ? -5.801 9.047 10.013 1.00 95.15 ? 69 ASP B OD1 69 ASP B OD1 1 ATOM 1899 O OD2 . ASP B 2 69 ? -7.899 8.445 10.219 1.00 95.15 ? 69 ASP B OD2 69 ASP B OD2 1 ATOM 1900 N N . SER B 2 70 ? -6.597 12.247 13.906 1.00 94.18 ? 70 SER B N 70 SER B N 1 ATOM 1901 C CA . SER B 2 70 ? -6.825 13.489 14.637 1.00 94.18 ? 70 SER B CA 70 SER B CA 1 ATOM 1902 C C . SER B 2 70 ? -5.523 14.259 14.837 1.00 94.18 ? 70 SER B C 70 SER B C 1 ATOM 1903 O O . SER B 2 70 ? -5.491 15.483 14.688 1.00 94.18 ? 70 SER B O 70 SER B O 1 ATOM 1904 C CB . SER B 2 70 ? -7.470 13.203 15.994 1.00 94.18 ? 70 SER B CB 70 SER B CB 1 ATOM 1905 O OG . SER B 2 70 ? -8.776 12.678 15.829 1.00 94.18 ? 70 SER B OG 70 SER B OG 1 ATOM 1906 N N . PHE B 2 71 ? -4.512 13.494 15.152 1.00 93.84 ? 71 PHE B N 71 PHE B N 1 ATOM 1907 C CA . PHE B 2 71 ? -3.190 14.076 15.353 1.00 93.84 ? 71 PHE B CA 71 PHE B CA 1 ATOM 1908 C C . PHE B 2 71 ? -2.686 14.731 14.073 1.00 93.84 ? 71 PHE B C 71 PHE B C 1 ATOM 1909 O O . PHE B 2 71 ? -2.154 15.842 14.105 1.00 93.84 ? 71 PHE B O 71 PHE B O 1 ATOM 1910 C CB . PHE B 2 71 ? -2.197 13.009 15.824 1.00 93.84 ? 71 PHE B CB 71 PHE B CB 1 ATOM 1911 C CG . PHE B 2 71 ? -0.795 13.524 16.008 1.00 93.84 ? 71 PHE B CG 71 PHE B CG 1 ATOM 1912 C CD1 . PHE B 2 71 ? 0.189 13.255 15.065 1.00 93.84 ? 71 PHE B CD1 71 PHE B CD1 1 ATOM 1913 C CD2 . PHE B 2 71 ? -0.461 14.278 17.126 1.00 93.84 ? 71 PHE B CD2 71 PHE B CD2 1 ATOM 1914 C CE1 . PHE B 2 71 ? 1.487 13.731 15.232 1.00 93.84 ? 71 PHE B CE1 71 PHE B CE1 1 ATOM 1915 C CE2 . PHE B 2 71 ? 0.835 14.757 17.300 1.00 93.84 ? 71 PHE B CE2 71 PHE B CE2 1 ATOM 1916 C CZ . PHE B 2 71 ? 1.807 14.481 16.353 1.00 93.84 ? 71 PHE B CZ 71 PHE B CZ 1 ATOM 1917 N N . ILE B 2 72 ? -2.847 14.124 12.984 1.00 94.29 ? 72 ILE B N 72 ILE B N 1 ATOM 1918 C CA . ILE B 2 72 ? -2.407 14.629 11.688 1.00 94.29 ? 72 ILE B CA 72 ILE B CA 1 ATOM 1919 C C . ILE B 2 72 ? -3.096 15.959 11.391 1.00 94.29 ? 72 ILE B C 72 ILE B C 1 ATOM 1920 O O . ILE B 2 72 ? -2.443 16.932 11.006 1.00 94.29 ? 72 ILE B O 72 ILE B O 1 ATOM 1921 C CB . ILE B 2 72 ? -2.692 13.613 10.559 1.00 94.29 ? 72 ILE B CB 72 ILE B CB 1 ATOM 1922 C CG1 . ILE B 2 72 ? -1.809 12.371 10.723 1.00 94.29 ? 72 ILE B CG1 72 ILE B CG1 1 ATOM 1923 C CG2 . ILE B 2 72 ? -2.481 14.258 9.186 1.00 94.29 ? 72 ILE B CG2 72 ILE B CG2 1 ATOM 1924 C CD1 . ILE B 2 72 ? -2.158 11.234 9.773 1.00 94.29 ? 72 ILE B CD1 72 ILE B CD1 1 ATOM 1925 N N . LEU B 2 73 ? -4.390 16.004 11.593 1.00 92.50 ? 73 LEU B N 73 LEU B N 1 ATOM 1926 C CA . LEU B 2 73 ? -5.160 17.205 11.289 1.00 92.50 ? 73 LEU B CA 73 LEU B CA 1 ATOM 1927 C C . LEU B 2 73 ? -4.762 18.354 12.210 1.00 92.50 ? 73 LEU B C 73 LEU B C 1 ATOM 1928 O O . LEU B 2 73 ? -4.679 19.505 11.774 1.00 92.50 ? 73 LEU B O 73 LEU B O 1 ATOM 1929 C CB . LEU B 2 73 ? -6.660 16.928 11.420 1.00 92.50 ? 73 LEU B CB 73 LEU B CB 1 ATOM 1930 C CG . LEU B 2 73 ? -7.328 16.236 10.230 1.00 92.50 ? 73 LEU B CG 73 LEU B CG 1 ATOM 1931 C CD1 . LEU B 2 73 ? -8.789 15.933 10.544 1.00 92.50 ? 73 LEU B CD1 73 LEU B CD1 1 ATOM 1932 C CD2 . LEU B 2 73 ? -7.213 17.097 8.977 1.00 92.50 ? 73 LEU B CD2 73 LEU B CD2 1 ATOM 1933 N N . THR B 2 74 ? -4.539 18.023 13.480 1.00 90.78 ? 74 THR B N 74 THR B N 1 ATOM 1934 C CA . THR B 2 74 ? -4.114 19.043 14.433 1.00 90.78 ? 74 THR B CA 74 THR B CA 1 ATOM 1935 C C . THR B 2 74 ? -2.766 19.633 14.028 1.00 90.78 ? 74 THR B C 74 THR B C 1 ATOM 1936 O O . THR B 2 74 ? -2.561 20.845 14.117 1.00 90.78 ? 74 THR B O 74 THR B O 1 ATOM 1937 C CB . THR B 2 74 ? -4.020 18.471 15.859 1.00 90.78 ? 74 THR B CB 74 THR B CB 1 ATOM 1938 O OG1 . THR B 2 74 ? -5.292 17.930 16.236 1.00 90.78 ? 74 THR B OG1 74 THR B OG1 1 ATOM 1939 C CG2 . THR B 2 74 ? -3.623 19.551 16.860 1.00 90.78 ? 74 THR B CG2 74 THR B CG2 1 ATOM 1940 N N . ARG B 2 75 ? -1.895 18.781 13.585 1.00 89.43 ? 75 ARG B N 75 ARG B N 1 ATOM 1941 C CA . ARG B 2 75 ? -0.578 19.235 13.153 1.00 89.43 ? 75 ARG B CA 75 ARG B CA 1 ATOM 1942 C C . ARG B 2 75 ? -0.677 20.072 11.881 1.00 89.43 ? 75 ARG B C 75 ARG B C 1 ATOM 1943 O O . ARG B 2 75 ? 0.048 21.057 11.722 1.00 89.43 ? 75 ARG B O 75 ARG B O 1 ATOM 1944 C CB . ARG B 2 75 ? 0.355 18.044 12.924 1.00 89.43 ? 75 ARG B CB 75 ARG B CB 1 ATOM 1945 C CG . ARG B 2 75 ? 0.793 17.351 14.205 1.00 89.43 ? 75 ARG B CG 75 ARG B CG 1 ATOM 1946 C CD . ARG B 2 75 ? 1.561 18.293 15.122 1.00 89.43 ? 75 ARG B CD 75 ARG B CD 1 ATOM 1947 N NE . ARG B 2 75 ? 1.738 17.723 16.454 1.00 89.43 ? 75 ARG B NE 75 ARG B NE 1 ATOM 1948 C CZ . ARG B 2 75 ? 2.221 18.383 17.503 1.00 89.43 ? 75 ARG B CZ 75 ARG B CZ 1 ATOM 1949 N NH1 . ARG B 2 75 ? 2.584 19.656 17.394 1.00 89.43 ? 75 ARG B NH1 75 ARG B NH1 1 ATOM 1950 N NH2 . ARG B 2 75 ? 2.340 17.767 18.670 1.00 89.43 ? 75 ARG B NH2 75 ARG B NH2 1 ATOM 1951 N N . LEU B 2 76 ? -1.509 19.659 10.982 1.00 89.73 ? 76 LEU B N 76 LEU B N 1 ATOM 1952 C CA . LEU B 2 76 ? -1.712 20.402 9.742 1.00 89.73 ? 76 LEU B CA 76 LEU B CA 1 ATOM 1953 C C . LEU B 2 76 ? -2.243 21.802 10.029 1.00 89.73 ? 76 LEU B C 76 LEU B C 1 ATOM 1954 O O . LEU B 2 76 ? -1.836 22.769 9.382 1.00 89.73 ? 76 LEU B O 76 LEU B O 1 ATOM 1955 C CB . LEU B 2 76 ? -2.680 19.654 8.822 1.00 89.73 ? 76 LEU B CB 76 LEU B CB 1 ATOM 1956 C CG . LEU B 2 76 ? -2.098 18.476 8.039 1.00 89.73 ? 76 LEU B CG 76 LEU B CG 1 ATOM 1957 C CD1 . LEU B 2 76 ? -3.216 17.669 7.388 1.00 89.73 ? 76 LEU B CD1 76 LEU B CD1 1 ATOM 1958 C CD2 . LEU B 2 76 ? -1.106 18.967 6.992 1.00 89.73 ? 76 LEU B CD2 76 LEU B CD2 1 ATOM 1959 N N . GLU B 2 77 ? -3.025 21.913 11.057 1.00 85.96 ? 77 GLU B N 77 GLU B N 1 ATOM 1960 C CA . GLU B 2 77 ? -3.612 23.196 11.429 1.00 85.96 ? 77 GLU B CA 77 GLU B CA 1 ATOM 1961 C C . GLU B 2 77 ? -2.589 24.091 12.124 1.00 85.96 ? 77 GLU B C 77 GLU B C 1 ATOM 1962 O O . GLU B 2 77 ? -2.578 25.306 11.917 1.00 85.96 ? 77 GLU B O 77 GLU B O 1 ATOM 1963 C CB . GLU B 2 77 ? -4.830 22.989 12.334 1.00 85.96 ? 77 GLU B CB 77 GLU B CB 1 ATOM 1964 C CG . GLU B 2 77 ? -6.064 22.488 11.599 1.00 85.96 ? 77 GLU B CG 77 GLU B CG 1 ATOM 1965 C CD . GLU B 2 77 ? -7.248 22.233 12.518 1.00 85.96 ? 77 GLU B CD 77 GLU B CD 1 ATOM 1966 O OE1 . GLU B 2 77 ? -8.338 21.872 12.018 1.00 85.96 ? 77 GLU B OE1 77 GLU B OE1 1 ATOM 1967 O OE2 . GLU B 2 77 ? -7.085 22.396 13.748 1.00 85.96 ? 77 GLU B OE2 77 GLU B OE2 1 ATOM 1968 N N . GLN B 2 78 ? -1.709 23.537 12.913 1.00 82.90 ? 78 GLN B N 78 GLN B N 1 ATOM 1969 C CA . GLN B 2 78 ? -0.720 24.277 13.690 1.00 82.90 ? 78 GLN B CA 78 GLN B CA 1 ATOM 1970 C C . GLN B 2 78 ? 0.365 24.859 12.788 1.00 82.90 ? 78 GLN B C 78 GLN B C 1 ATOM 1971 O O . GLN B 2 78 ? 0.767 26.012 12.956 1.00 82.90 ? 78 GLN B O 78 GLN B O 1 ATOM 1972 C CB . GLN B 2 78 ? -0.090 23.377 14.754 1.00 82.90 ? 78 GLN B CB 78 GLN B CB 1 ATOM 1973 C CG . GLN B 2 78 ? -1.018 23.060 15.920 1.00 82.90 ? 78 GLN B CG 78 GLN B CG 1 ATOM 1974 C CD . GLN B 2 78 ? -0.388 22.125 16.934 1.00 82.90 ? 78 GLN B CD 78 GLN B CD 1 ATOM 1975 O OE1 . GLN B 2 78 ? 0.706 21.595 16.715 1.00 82.90 ? 78 GLN B OE1 78 GLN B OE1 1 ATOM 1976 N NE2 . GLN B 2 78 ? -1.074 21.914 18.052 1.00 82.90 ? 78 GLN B NE2 78 GLN B NE2 1 ATOM 1977 N N . TYR B 2 79 ? 0.852 24.155 11.846 1.00 75.72 ? 79 TYR B N 79 TYR B N 1 ATOM 1978 C CA . TYR B 2 79 ? 2.047 24.557 11.112 1.00 75.72 ? 79 TYR B CA 79 TYR B CA 1 ATOM 1979 C C . TYR B 2 79 ? 1.679 25.201 9.781 1.00 75.72 ? 79 TYR B C 79 TYR B C 1 ATOM 1980 O O . TYR B 2 79 ? 2.417 26.045 9.267 1.00 75.72 ? 79 TYR B O 79 TYR B O 1 ATOM 1981 C CB . TYR B 2 79 ? 2.962 23.352 10.873 1.00 75.72 ? 79 TYR B CB 79 TYR B CB 1 ATOM 1982 C CG . TYR B 2 79 ? 3.785 22.966 12.078 1.00 75.72 ? 79 TYR B CG 79 TYR B CG 1 ATOM 1983 C CD1 . TYR B 2 79 ? 4.994 23.601 12.352 1.00 75.72 ? 79 TYR B CD1 79 TYR B CD1 1 ATOM 1984 C CD2 . TYR B 2 79 ? 3.356 21.967 12.945 1.00 75.72 ? 79 TYR B CD2 79 TYR B CD2 1 ATOM 1985 C CE1 . TYR B 2 79 ? 5.757 23.248 13.461 1.00 75.72 ? 79 TYR B CE1 79 TYR B CE1 1 ATOM 1986 C CE2 . TYR B 2 79 ? 4.110 21.605 14.056 1.00 75.72 ? 79 TYR B CE2 79 TYR B CE2 1 ATOM 1987 C CZ . TYR B 2 79 ? 5.307 22.251 14.306 1.00 75.72 ? 79 TYR B CZ 79 TYR B CZ 1 ATOM 1988 O OH . TYR B 2 79 ? 6.058 21.897 15.404 1.00 75.72 ? 79 TYR B OH 79 TYR B OH 1 ATOM 1989 N N . TYR B 2 80 ? 0.445 24.990 9.335 1.00 71.57 ? 80 TYR B N 80 TYR B N 1 ATOM 1990 C CA . TYR B 2 80 ? 0.222 25.443 7.967 1.00 71.57 ? 80 TYR B CA 80 TYR B CA 1 ATOM 1991 C C . TYR B 2 80 ? -1.142 26.108 7.828 1.00 71.57 ? 80 TYR B C 80 TYR B C 1 ATOM 1992 O O . TYR B 2 80 ? -1.728 26.116 6.742 1.00 71.57 ? 80 TYR B O 80 TYR B O 1 ATOM 1993 C CB . TYR B 2 80 ? 0.333 24.270 6.988 1.00 71.57 ? 80 TYR B CB 80 TYR B CB 1 ATOM 1994 C CG . TYR B 2 80 ? 1.723 23.691 6.888 1.00 71.57 ? 80 TYR B CG 80 TYR B CG 1 ATOM 1995 C CD1 . TYR B 2 80 ? 2.703 24.311 6.116 1.00 71.57 ? 80 TYR B CD1 80 TYR B CD1 1 ATOM 1996 C CD2 . TYR B 2 80 ? 2.060 22.524 7.565 1.00 71.57 ? 80 TYR B CD2 80 TYR B CD2 1 ATOM 1997 C CE1 . TYR B 2 80 ? 3.985 23.781 6.019 1.00 71.57 ? 80 TYR B CE1 80 TYR B CE1 1 ATOM 1998 C CE2 . TYR B 2 80 ? 3.339 21.985 7.476 1.00 71.57 ? 80 TYR B CE2 80 TYR B CE2 1 ATOM 1999 C CZ . TYR B 2 80 ? 4.294 22.620 6.702 1.00 71.57 ? 80 TYR B CZ 80 TYR B CZ 1 ATOM 2000 O OH . TYR B 2 80 ? 5.561 22.090 6.611 1.00 71.57 ? 80 TYR B OH 80 TYR B OH 1 ATOM 2001 N N . LYS B 2 81 ? -1.518 26.653 8.964 1.00 67.33 ? 81 LYS B N 81 LYS B N 1 ATOM 2002 C CA . LYS B 2 81 ? -2.750 27.436 8.905 1.00 67.33 ? 81 LYS B CA 81 LYS B CA 1 ATOM 2003 C C . LYS B 2 81 ? -2.552 28.710 8.089 1.00 67.33 ? 81 LYS B C 81 LYS B C 1 ATOM 2004 O O . LYS B 2 81 ? -1.583 29.443 8.298 1.00 67.33 ? 81 LYS B O 81 LYS B O 1 ATOM 2005 C CB . LYS B 2 81 ? -3.233 27.784 10.313 1.00 67.33 ? 81 LYS B CB 81 LYS B CB 1 ATOM 2006 C CG . LYS B 2 81 ? -4.665 28.297 10.367 1.00 67.33 ? 81 LYS B CG 81 LYS B CG 1 ATOM 2007 C CD . LYS B 2 81 ? -5.117 28.543 11.801 1.00 67.33 ? 81 LYS B CD 81 LYS B CD 1 ATOM 2008 C CE . LYS B 2 81 ? -6.522 29.128 11.852 1.00 67.33 ? 81 LYS B CE 81 LYS B CE 1 ATOM 2009 N NZ . LYS B 2 81 ? -6.974 29.359 13.257 1.00 67.33 ? 81 LYS B NZ 81 LYS B NZ 1 ATOM 2010 N N . ASN B 2 82 ? -3.125 28.820 6.814 1.00 66.16 ? 82 ASN B N 82 ASN B N 1 ATOM 2011 C CA . ASN B 2 82 ? -3.221 30.026 5.999 1.00 66.16 ? 82 ASN B CA 82 ASN B CA 1 ATOM 2012 C C . ASN B 2 82 ? -2.120 30.078 4.943 1.00 66.16 ? 82 ASN B C 82 ASN B C 1 ATOM 2013 O O . ASN B 2 82 ? -2.068 31.011 4.140 1.00 66.16 ? 82 ASN B O 82 ASN B O 1 ATOM 2014 C CB . ASN B 2 82 ? -3.169 31.276 6.881 1.00 66.16 ? 82 ASN B CB 82 ASN B CB 1 ATOM 2015 C CG . ASN B 2 82 ? -4.353 31.376 7.822 1.00 66.16 ? 82 ASN B CG 82 ASN B CG 1 ATOM 2016 O OD1 . ASN B 2 82 ? -5.468 30.970 7.483 1.00 66.16 ? 82 ASN B OD1 82 ASN B OD1 1 ATOM 2017 N ND2 . ASN B 2 82 ? -4.120 31.916 9.013 1.00 66.16 ? 82 ASN B ND2 82 ASN B ND2 1 ATOM 2018 N N . LYS B 2 83 ? -1.217 29.079 4.980 1.00 71.95 ? 83 LYS B N 83 LYS B N 1 ATOM 2019 C CA . LYS B 2 83 ? -0.120 29.153 4.019 1.00 71.95 ? 83 LYS B CA 83 LYS B CA 1 ATOM 2020 C C . LYS B 2 83 ? -0.468 28.416 2.729 1.00 71.95 ? 83 LYS B C 83 LYS B C 1 ATOM 2021 O O . LYS B 2 83 ? 0.001 28.786 1.651 1.00 71.95 ? 83 LYS B O 83 LYS B O 1 ATOM 2022 C CB . LYS B 2 83 ? 1.162 28.579 4.622 1.00 71.95 ? 83 LYS B CB 83 LYS B CB 1 ATOM 2023 C CG . LYS B 2 83 ? 1.822 29.484 5.651 1.00 71.95 ? 83 LYS B CG 83 LYS B CG 1 ATOM 2024 C CD . LYS B 2 83 ? 3.173 28.937 6.093 1.00 71.95 ? 83 LYS B CD 83 LYS B CD 1 ATOM 2025 C CE . LYS B 2 83 ? 3.819 29.824 7.149 1.00 71.95 ? 83 LYS B CE 83 LYS B CE 1 ATOM 2026 N NZ . LYS B 2 83 ? 5.166 29.319 7.548 1.00 71.95 ? 83 LYS B NZ 83 LYS B NZ 1 ATOM 2027 N N . VAL B 2 84 ? -1.416 27.536 2.924 1.00 74.24 ? 84 VAL B N 84 VAL B N 1 ATOM 2028 C CA . VAL B 2 84 ? -1.708 26.698 1.765 1.00 74.24 ? 84 VAL B CA 84 VAL B CA 1 ATOM 2029 C C . VAL B 2 84 ? -3.216 26.648 1.530 1.00 74.24 ? 84 VAL B C 84 VAL B C 1 ATOM 2030 O O . VAL B 2 84 ? -4.002 26.801 2.468 1.00 74.24 ? 84 VAL B O 84 VAL B O 1 ATOM 2031 C CB . VAL B 2 84 ? -1.148 25.269 1.943 1.00 74.24 ? 84 VAL B CB 84 VAL B CB 1 ATOM 2032 C CG1 . VAL B 2 84 ? -1.349 24.448 0.670 1.00 74.24 ? 84 VAL B CG1 84 VAL B CG1 1 ATOM 2033 C CG2 . VAL B 2 84 ? 0.331 25.320 2.322 1.00 74.24 ? 84 VAL B CG2 84 VAL B CG2 1 ATOM 2034 N N . ASN B 2 85 ? -3.610 26.559 0.253 1.00 76.73 ? 85 ASN B N 85 ASN B N 1 ATOM 2035 C CA . ASN B 2 85 ? -5.005 26.577 -0.174 1.00 76.73 ? 85 ASN B CA 85 ASN B CA 1 ATOM 2036 C C . ASN B 2 85 ? -5.741 25.312 0.259 1.00 76.73 ? 85 ASN B C 85 ASN B C 1 ATOM 2037 O O . ASN B 2 85 ? -6.866 25.383 0.756 1.00 76.73 ? 85 ASN B O 85 ASN B O 1 ATOM 2038 C CB . ASN B 2 85 ? -5.100 26.753 -1.691 1.00 76.73 ? 85 ASN B CB 85 ASN B CB 1 ATOM 2039 C CG . ASN B 2 85 ? -4.680 28.138 -2.146 1.00 76.73 ? 85 ASN B CG 85 ASN B CG 1 ATOM 2040 O OD1 . ASN B 2 85 ? -4.752 29.103 -1.381 1.00 76.73 ? 85 ASN B OD1 85 ASN B OD1 1 ATOM 2041 N ND2 . ASN B 2 85 ? -4.239 28.244 -3.393 1.00 76.73 ? 85 ASN B ND2 85 ASN B ND2 1 ATOM 2042 N N . GLU B 2 86 ? -5.010 24.130 0.093 1.00 83.34 ? 86 GLU B N 86 GLU B N 1 ATOM 2043 C CA . GLU B 2 86 ? -5.617 22.838 0.400 1.00 83.34 ? 86 GLU B CA 86 GLU B CA 1 ATOM 2044 C C . GLU B 2 86 ? -4.651 21.946 1.175 1.00 83.34 ? 86 GLU B C 86 GLU B C 1 ATOM 2045 O O . GLU B 2 86 ? -3.476 21.839 0.820 1.00 83.34 ? 86 GLU B O 86 GLU B O 1 ATOM 2046 C CB . GLU B 2 86 ? -6.066 22.137 -0.884 1.00 83.34 ? 86 GLU B CB 86 GLU B CB 1 ATOM 2047 C CG . GLU B 2 86 ? -6.897 20.885 -0.642 1.00 83.34 ? 86 GLU B CG 86 GLU B CG 1 ATOM 2048 C CD . GLU B 2 86 ? -7.339 20.201 -1.926 1.00 83.34 ? 86 GLU B CD 86 GLU B CD 1 ATOM 2049 O OE1 . GLU B 2 86 ? -8.060 19.179 -1.853 1.00 83.34 ? 86 GLU B OE1 86 GLU B OE1 1 ATOM 2050 O OE2 . GLU B 2 86 ? -6.961 20.689 -3.014 1.00 83.34 ? 86 GLU B OE2 86 GLU B OE2 1 ATOM 2051 N N . ARG B 2 87 ? -5.213 21.357 2.296 1.00 87.16 ? 87 ARG B N 87 ARG B N 1 ATOM 2052 C CA . ARG B 2 87 ? -4.427 20.438 3.114 1.00 87.16 ? 87 ARG B CA 87 ARG B CA 1 ATOM 2053 C C . ARG B 2 87 ? -5.321 19.397 3.780 1.00 87.16 ? 87 ARG B C 87 ARG B C 1 ATOM 2054 O O . ARG B 2 87 ? -6.507 19.644 4.008 1.00 87.16 ? 87 ARG B O 87 ARG B O 1 ATOM 2055 C CB . ARG B 2 87 ? -3.634 21.205 4.174 1.00 87.16 ? 87 ARG B CB 87 ARG B CB 1 ATOM 2056 C CG . ARG B 2 87 ? -4.504 21.892 5.216 1.00 87.16 ? 87 ARG B CG 87 ARG B CG 1 ATOM 2057 C CD . ARG B 2 87 ? -3.700 22.864 6.068 1.00 87.16 ? 87 ARG B CD 87 ARG B CD 1 ATOM 2058 N NE . ARG B 2 87 ? -4.520 23.468 7.114 1.00 87.16 ? 87 ARG B NE 87 ARG B NE 1 ATOM 2059 C CZ . ARG B 2 87 ? -5.058 24.683 7.049 1.00 87.16 ? 87 ARG B CZ 87 ARG B CZ 1 ATOM 2060 N NH1 . ARG B 2 87 ? -4.872 25.451 5.981 1.00 87.16 ? 87 ARG B NH1 87 ARG B NH1 1 ATOM 2061 N NH2 . ARG B 2 87 ? -5.788 25.134 8.059 1.00 87.16 ? 87 ARG B NH2 87 ARG B NH2 1 ATOM 2062 N N . GLY B 2 88 ? -4.740 18.355 3.940 1.00 90.37 ? 88 GLY B N 88 GLY B N 1 ATOM 2063 C CA . GLY B 2 88 ? -5.538 17.351 4.627 1.00 90.37 ? 88 GLY B CA 88 GLY B CA 1 ATOM 2064 C C . GLY B 2 88 ? -4.953 15.955 4.530 1.00 90.37 ? 88 GLY B C 88 GLY B C 1 ATOM 2065 O O . GLY B 2 88 ? -3.778 15.791 4.195 1.00 90.37 ? 88 GLY B O 88 GLY B O 1 ATOM 2066 N N . ILE B 2 89 ? -5.729 15.046 4.992 1.00 92.79 ? 89 ILE B N 89 ILE B N 1 ATOM 2067 C CA . ILE B 2 89 ? -5.347 13.638 4.977 1.00 92.79 ? 89 ILE B CA 89 ILE B CA 1 ATOM 2068 C C . ILE B 2 89 ? -5.529 13.069 3.572 1.00 92.79 ? 89 ILE B C 89 ILE B C 1 ATOM 2069 O O . ILE B 2 89 ? -6.626 13.122 3.011 1.00 92.79 ? 89 ILE B O 89 ILE B O 1 ATOM 2070 C CB . ILE B 2 89 ? -6.169 12.819 5.998 1.00 92.79 ? 89 ILE B CB 89 ILE B CB 1 ATOM 2071 C CG1 . ILE B 2 89 ? -5.967 13.372 7.413 1.00 92.79 ? 89 ILE B CG1 89 ILE B CG1 1 ATOM 2072 C CG2 . ILE B 2 89 ? -5.791 11.336 5.930 1.00 92.79 ? 89 ILE B CG2 89 ILE B CG2 1 ATOM 2073 C CD1 . ILE B 2 89 ? -6.916 12.785 8.448 1.00 92.79 ? 89 ILE B CD1 89 ILE B CD1 1 ATOM 2074 N N . ALA B 2 90 ? -4.456 12.625 2.982 1.00 91.77 ? 90 ALA B N 90 ALA B N 1 ATOM 2075 C CA . ALA B 2 90 ? -4.520 11.990 1.668 1.00 91.77 ? 90 ALA B CA 90 ALA B CA 1 ATOM 2076 C C . ALA B 2 90 ? -4.990 10.543 1.780 1.00 91.77 ? 90 ALA B C 90 ALA B C 1 ATOM 2077 O O . ALA B 2 90 ? -5.822 10.091 0.990 1.00 91.77 ? 90 ALA B O 90 ALA B O 1 ATOM 2078 C CB . ALA B 2 90 ? -3.159 12.053 0.980 1.00 91.77 ? 90 ALA B CB 90 ALA B CB 1 ATOM 2079 N N . ILE B 2 91 ? -4.462 9.816 2.750 1.00 92.38 ? 91 ILE B N 91 ILE B N 1 ATOM 2080 C CA . ILE B 2 91 ? -4.826 8.439 3.066 1.00 92.38 ? 91 ILE B CA 91 ILE B CA 1 ATOM 2081 C C . ILE B 2 91 ? -5.094 8.307 4.563 1.00 92.38 ? 91 ILE B C 91 ILE B C 1 ATOM 2082 O O . ILE B 2 91 ? -4.186 8.475 5.380 1.00 92.38 ? 91 ILE B O 91 ILE B O 1 ATOM 2083 C CB . ILE B 2 91 ? -3.723 7.449 2.630 1.00 92.38 ? 91 ILE B CB 91 ILE B CB 1 ATOM 2084 C CG1 . ILE B 2 91 ? -3.453 7.579 1.126 1.00 92.38 ? 91 ILE B CG1 91 ILE B CG1 1 ATOM 2085 C CG2 . ILE B 2 91 ? -4.112 6.013 2.994 1.00 92.38 ? 91 ILE B CG2 91 ILE B CG2 1 ATOM 2086 C CD1 . ILE B 2 91 ? -2.220 6.822 0.652 1.00 92.38 ? 91 ILE B CD1 91 ILE B CD1 1 ATOM 2087 N N . PRO B 2 92 ? -6.375 8.003 4.826 1.00 93.77 ? 92 PRO B N 92 PRO B N 1 ATOM 2088 C CA . PRO B 2 92 ? -6.625 7.788 6.253 1.00 93.77 ? 92 PRO B CA 92 PRO B CA 1 ATOM 2089 C C . PRO B 2 92 ? -5.795 6.645 6.832 1.00 93.77 ? 92 PRO B C 92 PRO B C 1 ATOM 2090 O O . PRO B 2 92 ? -5.403 5.730 6.103 1.00 93.77 ? 92 PRO B O 92 PRO B O 1 ATOM 2091 C CB . PRO B 2 92 ? -8.119 7.458 6.303 1.00 93.77 ? 92 PRO B CB 92 PRO B CB 1 ATOM 2092 C CG . PRO B 2 92 ? -8.667 7.968 5.009 1.00 93.77 ? 92 PRO B CG 92 PRO B CG 1 ATOM 2093 C CD . PRO B 2 92 ? -7.569 7.946 3.984 1.00 93.77 ? 92 PRO B CD 92 PRO B CD 1 ATOM 2094 N N . THR B 2 93 ? -5.524 6.784 8.120 1.00 95.55 ? 93 THR B N 93 THR B N 1 ATOM 2095 C CA . THR B 2 93 ? -4.687 5.791 8.784 1.00 95.55 ? 93 THR B CA 93 THR B CA 1 ATOM 2096 C C . THR B 2 93 ? -5.361 4.422 8.775 1.00 95.55 ? 93 THR B C 93 THR B C 1 ATOM 2097 O O . THR B 2 93 ? -6.529 4.296 9.147 1.00 95.55 ? 93 THR B O 93 THR B O 1 ATOM 2098 C CB . THR B 2 93 ? -4.376 6.203 10.235 1.00 95.55 ? 93 THR B CB 93 THR B CB 1 ATOM 2099 O OG1 . THR B 2 93 ? -3.778 7.505 10.238 1.00 95.55 ? 93 THR B OG1 93 THR B OG1 1 ATOM 2100 C CG2 . THR B 2 93 ? -3.418 5.215 10.894 1.00 95.55 ? 93 THR B CG2 93 THR B CG2 1 ATOM 2101 N N . THR B 2 94 ? -4.621 3.454 8.223 1.00 95.12 ? 94 THR B N 94 THR B N 1 ATOM 2102 C CA . THR B 2 94 ? -5.080 2.069 8.208 1.00 95.12 ? 94 THR B CA 94 THR B CA 1 ATOM 2103 C C . THR B 2 94 ? -4.036 1.146 8.830 1.00 95.12 ? 94 THR B C 94 THR B C 1 ATOM 2104 O O . THR B 2 94 ? -2.836 1.318 8.605 1.00 95.12 ? 94 THR B O 94 THR B O 1 ATOM 2105 C CB . THR B 2 94 ? -5.395 1.601 6.775 1.00 95.12 ? 94 THR B CB 94 THR B CB 1 ATOM 2106 O OG1 . THR B 2 94 ? -4.200 1.661 5.986 1.00 95.12 ? 94 THR B OG1 94 THR B OG1 1 ATOM 2107 C CG2 . THR B 2 94 ? -6.461 2.481 6.130 1.00 95.12 ? 94 THR B CG2 94 THR B CG2 1 ATOM 2108 N N . ILE B 2 95 ? -4.509 0.235 9.680 1.00 96.40 ? 95 ILE B N 95 ILE B N 1 ATOM 2109 C CA . ILE B 2 95 ? -3.641 -0.776 10.275 1.00 96.40 ? 95 ILE B CA 95 ILE B CA 1 ATOM 2110 C C . ILE B 2 95 ? -4.090 -2.166 9.832 1.00 96.40 ? 95 ILE B C 95 ILE B C 1 ATOM 2111 O O . ILE B 2 95 ? -5.107 -2.678 10.307 1.00 96.40 ? 95 ILE B O 95 ILE B O 1 ATOM 2112 C CB . ILE B 2 95 ? -3.637 -0.679 11.817 1.00 96.40 ? 95 ILE B CB 95 ILE B CB 1 ATOM 2113 C CG1 . ILE B 2 95 ? -3.111 0.689 12.265 1.00 96.40 ? 95 ILE B CG1 95 ILE B CG1 1 ATOM 2114 C CG2 . ILE B 2 95 ? -2.805 -1.812 12.426 1.00 96.40 ? 95 ILE B CG2 95 ILE B CG2 1 ATOM 2115 C CD1 . ILE B 2 95 ? -3.176 0.915 13.769 1.00 96.40 ? 95 ILE B CD1 95 ILE B CD1 1 ATOM 2116 N N . ASP B 2 96 ? -3.337 -2.722 8.921 1.00 96.08 ? 96 ASP B N 96 ASP B N 1 ATOM 2117 C CA . ASP B 2 96 ? -3.588 -4.068 8.414 1.00 96.08 ? 96 ASP B CA 96 ASP B CA 1 ATOM 2118 C C . ASP B 2 96 ? -2.762 -5.104 9.173 1.00 96.08 ? 96 ASP B C 96 ASP B C 1 ATOM 2119 O O . ASP B 2 96 ? -1.578 -4.888 9.439 1.00 96.08 ? 96 ASP B O 96 ASP B O 1 ATOM 2120 C CB . ASP B 2 96 ? -3.280 -4.144 6.917 1.00 96.08 ? 96 ASP B CB 96 ASP B CB 1 ATOM 2121 C CG . ASP B 2 96 ? -4.016 -3.092 6.106 1.00 96.08 ? 96 ASP B CG 96 ASP B CG 1 ATOM 2122 O OD1 . ASP B 2 96 ? -5.261 -3.019 6.190 1.00 96.08 ? 96 ASP B OD1 96 ASP B OD1 1 ATOM 2123 O OD2 . ASP B 2 96 ? -3.346 -2.332 5.374 1.00 96.08 ? 96 ASP B OD2 96 ASP B OD2 1 ATOM 2124 N N . ILE B 2 97 ? -3.448 -6.238 9.425 1.00 95.92 ? 97 ILE B N 97 ILE B N 1 ATOM 2125 C CA . ILE B 2 97 ? -2.779 -7.224 10.268 1.00 95.92 ? 97 ILE B CA 97 ILE B CA 1 ATOM 2126 C C . ILE B 2 97 ? -2.588 -8.524 9.490 1.00 95.92 ? 97 ILE B C 97 ILE B C 1 ATOM 2127 O O . ILE B 2 97 ? -3.541 -9.059 8.919 1.00 95.92 ? 97 ILE B O 97 ILE B O 1 ATOM 2128 C CB . ILE B 2 97 ? -3.573 -7.489 11.567 1.00 95.92 ? 97 ILE B CB 97 ILE B CB 1 ATOM 2129 C CG1 . ILE B 2 97 ? -3.807 -6.178 12.326 1.00 95.92 ? 97 ILE B CG1 97 ILE B CG1 1 ATOM 2130 C CG2 . ILE B 2 97 ? -2.845 -8.509 12.447 1.00 95.92 ? 97 ILE B CG2 97 ILE B CG2 1 ATOM 2131 C CD1 . ILE B 2 97 ? -4.896 -6.263 13.387 1.00 95.92 ? 97 ILE B CD1 97 ILE B CD1 1 ATOM 2132 N N . ASP B 2 98 ? -1.421 -9.048 9.447 1.00 95.08 ? 98 ASP B N 98 ASP B N 1 ATOM 2133 C CA . ASP B 2 98 ? -1.040 -10.362 8.940 1.00 95.08 ? 98 ASP B CA 98 ASP B CA 1 ATOM 2134 C C . ASP B 2 98 ? -1.471 -10.535 7.485 1.00 95.08 ? 98 ASP B C 98 ASP B C 1 ATOM 2135 O O . ASP B 2 98 ? -0.913 -9.900 6.588 1.00 95.08 ? 98 ASP B O 98 ASP B O 1 ATOM 2136 C CB . ASP B 2 98 ? -1.649 -11.468 9.804 1.00 95.08 ? 98 ASP B CB 98 ASP B CB 1 ATOM 2137 C CG . ASP B 2 98 ? -0.976 -11.602 11.159 1.00 95.08 ? 98 ASP B CG 98 ASP B CG 1 ATOM 2138 O OD1 . ASP B 2 98 ? 0.256 -11.407 11.249 1.00 95.08 ? 98 ASP B OD1 98 ASP B OD1 1 ATOM 2139 O OD2 . ASP B 2 98 ? -1.682 -11.907 12.144 1.00 95.08 ? 98 ASP B OD2 98 ASP B OD2 1 ATOM 2140 N N . GLN B 2 99 ? -2.610 -11.276 7.217 1.00 94.66 ? 99 GLN B N 99 GLN B N 1 ATOM 2141 C CA . GLN B 2 99 ? -3.012 -11.700 5.880 1.00 94.66 ? 99 GLN B CA 99 GLN B CA 1 ATOM 2142 C C . GLN B 2 99 ? -3.711 -10.569 5.131 1.00 94.66 ? 99 GLN B C 99 GLN B C 1 ATOM 2143 O O . GLN B 2 99 ? -3.800 -10.593 3.902 1.00 94.66 ? 99 GLN B O 99 GLN B O 1 ATOM 2144 C CB . GLN B 2 99 ? -3.928 -12.923 5.957 1.00 94.66 ? 99 GLN B CB 99 GLN B CB 1 ATOM 2145 C CG . GLN B 2 99 ? -3.292 -14.125 6.643 1.00 94.66 ? 99 GLN B CG 99 GLN B CG 1 ATOM 2146 C CD . GLN B 2 99 ? -3.472 -14.104 8.149 1.00 94.66 ? 99 GLN B CD 99 GLN B CD 1 ATOM 2147 O OE1 . GLN B 2 99 ? -4.054 -13.167 8.705 1.00 94.66 ? 99 GLN B OE1 99 GLN B OE1 1 ATOM 2148 N NE2 . GLN B 2 99 ? -2.973 -15.136 8.820 1.00 94.66 ? 99 GLN B NE2 99 GLN B NE2 1 ATOM 2149 N N . ILE B 2 100 ? -4.195 -9.576 5.878 1.00 95.46 ? 100 ILE B N 100 ILE B N 1 ATOM 2150 C CA . ILE B 2 100 ? -4.882 -8.457 5.242 1.00 95.46 ? 100 ILE B CA 100 ILE B CA 1 ATOM 2151 C C . ILE B 2 100 ? -3.876 -7.601 4.478 1.00 95.46 ? 100 ILE B C 100 ILE B C 1 ATOM 2152 O O . ILE B 2 100 ? -2.965 -7.021 5.074 1.00 95.46 ? 100 ILE B O 100 ILE B O 1 ATOM 2153 C CB . ILE B 2 100 ? -5.641 -7.597 6.277 1.00 95.46 ? 100 ILE B CB 100 ILE B CB 1 ATOM 2154 C CG1 . ILE B 2 100 ? -6.725 -8.430 6.972 1.00 95.46 ? 100 ILE B CG1 100 ILE B CG1 1 ATOM 2155 C CG2 . ILE B 2 100 ? -6.246 -6.358 5.611 1.00 95.46 ? 100 ILE B CG2 100 ILE B CG2 1 ATOM 2156 C CD1 . ILE B 2 100 ? -7.433 -7.702 8.107 1.00 95.46 ? 100 ILE B CD1 100 ILE B CD1 1 ATOM 2157 N N . SER B 2 101 ? -3.999 -7.574 3.158 1.00 93.65 ? 101 SER B N 101 SER B N 1 ATOM 2158 C CA . SER B 2 101 ? -3.059 -6.856 2.304 1.00 93.65 ? 101 SER B CA 101 SER B CA 1 ATOM 2159 C C . SER B 2 101 ? -3.291 -5.350 2.371 1.00 93.65 ? 101 SER B C 101 SER B C 1 ATOM 2160 O O . SER B 2 101 ? -2.336 -4.570 2.400 1.00 93.65 ? 101 SER B O 101 SER B O 1 ATOM 2161 C CB . SER B 2 101 ? -3.177 -7.334 0.856 1.00 93.65 ? 101 SER B CB 101 SER B CB 1 ATOM 2162 O OG . SER B 2 101 ? -2.330 -6.579 0.007 1.00 93.65 ? 101 SER B OG 101 SER B OG 1 ATOM 2163 N N . GLY B 2 102 ? -4.597 -4.959 2.463 1.00 91.36 ? 102 GLY B N 102 GLY B N 1 ATOM 2164 C CA . GLY B 2 102 ? -4.924 -3.542 2.477 1.00 91.36 ? 102 GLY B CA 102 GLY B CA 1 ATOM 2165 C C . GLY B 2 102 ? -6.413 -3.274 2.583 1.00 91.36 ? 102 GLY B C 102 GLY B C 1 ATOM 2166 O O . GLY B 2 102 ? -7.224 -4.199 2.491 1.00 91.36 ? 102 GLY B O 102 GLY B O 1 ATOM 2167 N N . GLY B 2 103 ? -6.708 -2.056 3.029 1.00 86.41 ? 103 GLY B N 103 GLY B N 1 ATOM 2168 C CA . GLY B 2 103 ? -8.083 -1.583 3.019 1.00 86.41 ? 103 GLY B CA 103 GLY B CA 1 ATOM 2169 C C . GLY B 2 103 ? -8.786 -1.766 4.351 1.00 86.41 ? 103 GLY B C 103 GLY B C 1 ATOM 2170 O O . GLY B 2 103 ? -9.965 -1.431 4.487 1.00 86.41 ? 103 GLY B O 103 GLY B O 1 ATOM 2171 N N . TRP B 2 104 ? -8.066 -2.298 5.290 1.00 92.07 ? 104 TRP B N 104 TRP B N 1 ATOM 2172 C CA . TRP B 2 104 ? -8.667 -2.519 6.602 1.00 92.07 ? 104 TRP B CA 104 TRP B CA 1 ATOM 2173 C C . TRP B 2 104 ? -8.714 -1.224 7.404 1.00 92.07 ? 104 TRP B C 104 TRP B C 1 ATOM 2174 O O . TRP B 2 104 ? -7.685 -0.750 7.891 1.00 92.07 ? 104 TRP B O 104 TRP B O 1 ATOM 2175 C CB . TRP B 2 104 ? -7.890 -3.587 7.377 1.00 92.07 ? 104 TRP B CB 104 TRP B CB 1 ATOM 2176 C CG . TRP B 2 104 ? -8.557 -4.025 8.646 1.00 92.07 ? 104 TRP B CG 104 TRP B CG 1 ATOM 2177 C CD1 . TRP B 2 104 ? -8.256 -3.621 9.917 1.00 92.07 ? 104 TRP B CD1 104 TRP B CD1 1 ATOM 2178 C CD2 . TRP B 2 104 ? -9.637 -4.956 8.766 1.00 92.07 ? 104 TRP B CD2 104 TRP B CD2 1 ATOM 2179 N NE1 . TRP B 2 104 ? -9.085 -4.245 10.820 1.00 92.07 ? 104 TRP B NE1 104 TRP B NE1 1 ATOM 2180 C CE2 . TRP B 2 104 ? -9.941 -5.069 10.141 1.00 92.07 ? 104 TRP B CE2 104 TRP B CE2 1 ATOM 2181 C CE3 . TRP B 2 104 ? -10.378 -5.706 7.843 1.00 92.07 ? 104 TRP B CE3 104 TRP B CE3 1 ATOM 2182 C CZ2 . TRP B 2 104 ? -10.956 -5.903 10.615 1.00 92.07 ? 104 TRP B CZ2 104 TRP B CZ2 1 ATOM 2183 C CZ3 . TRP B 2 104 ? -11.388 -6.536 8.317 1.00 92.07 ? 104 TRP B CZ3 104 TRP B CZ3 1 ATOM 2184 C CH2 . TRP B 2 104 ? -11.666 -6.626 9.691 1.00 92.07 ? 104 TRP B CH2 104 TRP B CH2 1 ATOM 2185 N N . CYS B 2 105 ? -9.822 -0.642 7.498 1.00 87.84 ? 105 CYS B N 105 CYS B N 1 ATOM 2186 C CA . CYS B 2 105 ? -10.001 0.621 8.206 1.00 87.84 ? 105 CYS B CA 105 CYS B CA 1 ATOM 2187 C C . CYS B 2 105 ? -11.326 0.643 8.958 1.00 87.84 ? 105 CYS B C 105 CYS B C 1 ATOM 2188 O O . CYS B 2 105 ? -12.247 1.369 8.581 1.00 87.84 ? 105 CYS B O 105 CYS B O 1 ATOM 2189 C CB . CYS B 2 105 ? -9.939 1.796 7.230 1.00 87.84 ? 105 CYS B CB 105 CYS B CB 1 ATOM 2190 S SG . CYS B 2 105 ? -9.969 3.413 8.034 1.00 87.84 ? 105 CYS B SG 105 CYS B SG 1 ATOM 2191 N N . PRO B 2 106 ? -11.390 -0.137 10.032 1.00 88.59 ? 106 PRO B N 106 PRO B N 1 ATOM 2192 C CA . PRO B 2 106 ? -12.675 -0.179 10.735 1.00 88.59 ? 106 PRO B CA 106 PRO B CA 1 ATOM 2193 C C . PRO B 2 106 ? -12.956 1.096 11.527 1.00 88.59 ? 106 PRO B C 106 PRO B C 1 ATOM 2194 O O . PRO B 2 106 ? -12.023 1.773 11.965 1.00 88.59 ? 106 PRO B O 106 PRO B O 1 ATOM 2195 C CB . PRO B 2 106 ? -12.526 -1.381 11.670 1.00 88.59 ? 106 PRO B CB 106 PRO B CB 1 ATOM 2196 C CG . PRO B 2 106 ? -11.059 -1.474 11.943 1.00 88.59 ? 106 PRO B CG 106 PRO B CG 1 ATOM 2197 C CD . PRO B 2 106 ? -10.317 -1.031 10.715 1.00 88.59 ? 106 PRO B CD 106 PRO B CD 1 ATOM 2198 N N . GLU B 2 107 ? -14.188 1.454 11.652 1.00 91.11 ? 107 GLU B N 107 GLU B N 1 ATOM 2199 C CA . GLU B 2 107 ? -14.628 2.595 12.449 1.00 91.11 ? 107 GLU B CA 107 GLU B CA 1 ATOM 2200 C C . GLU B 2 107 ? -14.849 2.199 13.906 1.00 91.11 ? 107 GLU B C 107 GLU B C 1 ATOM 2201 O O . GLU B 2 107 ? -14.935 1.011 14.226 1.00 91.11 ? 107 GLU B O 107 GLU B O 1 ATOM 2202 C CB . GLU B 2 107 ? -15.911 3.195 11.867 1.00 91.11 ? 107 GLU B CB 107 GLU B CB 1 ATOM 2203 C CG . GLU B 2 107 ? -15.742 3.764 10.466 1.00 91.11 ? 107 GLU B CG 107 GLU B CG 1 ATOM 2204 C CD . GLU B 2 107 ? -15.126 5.154 10.453 1.00 91.11 ? 107 GLU B CD 107 GLU B CD 1 ATOM 2205 O OE1 . GLU B 2 107 ? -15.013 5.758 9.362 1.00 91.11 ? 107 GLU B OE1 107 GLU B OE1 1 ATOM 2206 O OE2 . GLU B 2 107 ? -14.752 5.643 11.543 1.00 91.11 ? 107 GLU B OE2 107 GLU B OE2 1 ATOM 2207 N N . ILE B 2 108 ? -14.889 3.100 14.843 1.00 89.93 ? 108 ILE B N 108 ILE B N 1 ATOM 2208 C CA . ILE B 2 108 ? -14.958 2.880 16.283 1.00 89.93 ? 108 ILE B CA 108 ILE B CA 1 ATOM 2209 C C . ILE B 2 108 ? -16.260 2.163 16.634 1.00 89.93 ? 108 ILE B C 108 ILE B C 1 ATOM 2210 O O . ILE B 2 108 ? -16.314 1.399 17.600 1.00 89.93 ? 108 ILE B O 108 ILE B O 1 ATOM 2211 C CB . ILE B 2 108 ? -14.850 4.209 17.064 1.00 89.93 ? 108 ILE B CB 108 ILE B CB 1 ATOM 2212 C CG1 . ILE B 2 108 ? -14.364 3.949 18.495 1.00 89.93 ? 108 ILE B CG1 108 ILE B CG1 1 ATOM 2213 C CG2 . ILE B 2 108 ? -16.194 4.943 17.067 1.00 89.93 ? 108 ILE B CG2 108 ILE B CG2 1 ATOM 2214 C CD1 . ILE B 2 108 ? -12.849 3.951 18.643 1.00 89.93 ? 108 ILE B CD1 108 ILE B CD1 1 ATOM 2215 N N . ASP B 2 109 ? -17.298 2.304 15.948 1.00 87.98 ? 109 ASP B N 109 ASP B N 1 ATOM 2216 C CA . ASP B 2 109 ? -18.583 1.701 16.288 1.00 87.98 ? 109 ASP B CA 109 ASP B CA 1 ATOM 2217 C C . ASP B 2 109 ? -18.682 0.277 15.745 1.00 87.98 ? 109 ASP B C 109 ASP B C 1 ATOM 2218 O O . ASP B 2 109 ? -19.647 -0.436 16.030 1.00 87.98 ? 109 ASP B O 109 ASP B O 1 ATOM 2219 C CB . ASP B 2 109 ? -19.735 2.551 15.746 1.00 87.98 ? 109 ASP B CB 109 ASP B CB 1 ATOM 2220 C CG . ASP B 2 109 ? -19.723 2.670 14.232 1.00 87.98 ? 109 ASP B CG 109 ASP B CG 1 ATOM 2221 O OD1 . ASP B 2 109 ? -18.628 2.748 13.635 1.00 87.98 ? 109 ASP B OD1 109 ASP B OD1 1 ATOM 2222 O OD2 . ASP B 2 109 ? -20.819 2.690 13.632 1.00 87.98 ? 109 ASP B OD2 109 ASP B OD2 1 ATOM 2223 N N . ASP B 2 110 ? -17.607 -0.185 14.931 1.00 85.97 ? 110 ASP B N 110 ASP B N 1 ATOM 2224 C CA . ASP B 2 110 ? -17.637 -1.465 14.230 1.00 85.97 ? 110 ASP B CA 110 ASP B CA 1 ATOM 2225 C C . ASP B 2 110 ? -17.151 -2.597 15.133 1.00 85.97 ? 110 ASP B C 110 ASP B C 1 ATOM 2226 O O . ASP B 2 110 ? -17.328 -3.774 14.812 1.00 85.97 ? 110 ASP B O 110 ASP B O 1 ATOM 2227 C CB . ASP B 2 110 ? -16.786 -1.403 12.960 1.00 85.97 ? 110 ASP B CB 110 ASP B CB 1 ATOM 2228 C CG . ASP B 2 110 ? -17.485 -0.696 11.812 1.00 85.97 ? 110 ASP B CG 110 ASP B CG 1 ATOM 2229 O OD1 . ASP B 2 110 ? -18.728 -0.567 11.842 1.00 85.97 ? 110 ASP B OD1 110 ASP B OD1 1 ATOM 2230 O OD2 . ASP B 2 110 ? -16.787 -0.268 10.868 1.00 85.97 ? 110 ASP B OD2 110 ASP B OD2 1 ATOM 2231 N N . THR B 2 111 ? -16.640 -2.294 16.238 1.00 85.30 ? 111 THR B N 111 THR B N 1 ATOM 2232 C CA . THR B 2 111 ? -15.968 -3.305 17.046 1.00 85.30 ? 111 THR B CA 111 THR B CA 1 ATOM 2233 C C . THR B 2 111 ? -16.943 -4.404 17.458 1.00 85.30 ? 111 THR B C 111 THR B C 1 ATOM 2234 O O . THR B 2 111 ? -16.644 -5.592 17.316 1.00 85.30 ? 111 THR B O 111 THR B O 1 ATOM 2235 C CB . THR B 2 111 ? -15.331 -2.683 18.303 1.00 85.30 ? 111 THR B CB 111 THR B CB 1 ATOM 2236 O OG1 . THR B 2 111 ? -16.308 -1.883 18.980 1.00 85.30 ? 111 THR B OG1 111 THR B OG1 1 ATOM 2237 C CG2 . THR B 2 111 ? -14.137 -1.806 17.938 1.00 85.30 ? 111 THR B CG2 111 THR B CG2 1 ATOM 2238 N N . GLN B 2 112 ? -18.122 -4.030 17.857 1.00 87.11 ? 112 GLN B N 112 GLN B N 1 ATOM 2239 C CA . GLN B 2 112 ? -19.118 -4.995 18.310 1.00 87.11 ? 112 GLN B CA 112 GLN B CA 1 ATOM 2240 C C . GLN B 2 112 ? -19.716 -5.762 17.134 1.00 87.11 ? 112 GLN B C 112 GLN B C 1 ATOM 2241 O O . GLN B 2 112 ? -19.915 -6.976 17.215 1.00 87.11 ? 112 GLN B O 112 GLN B O 1 ATOM 2242 C CB . GLN B 2 112 ? -20.226 -4.294 19.098 1.00 87.11 ? 112 GLN B CB 112 GLN B CB 1 ATOM 2243 C CG . GLN B 2 112 ? -19.769 -3.734 20.438 1.00 87.11 ? 112 GLN B CG 112 GLN B CG 1 ATOM 2244 C CD . GLN B 2 112 ? -20.883 -3.036 21.194 1.00 87.11 ? 112 GLN B CD 112 GLN B CD 1 ATOM 2245 O OE1 . GLN B 2 112 ? -21.960 -2.782 20.644 1.00 87.11 ? 112 GLN B OE1 112 GLN B OE1 1 ATOM 2246 N NE2 . GLN B 2 112 ? -20.634 -2.720 22.460 1.00 87.11 ? 112 GLN B NE2 112 GLN B NE2 1 ATOM 2247 N N . ASN B 2 113 ? -19.928 -5.093 16.054 1.00 87.87 ? 113 ASN B N 113 ASN B N 1 ATOM 2248 C CA . ASN B 2 113 ? -20.480 -5.703 14.849 1.00 87.87 ? 113 ASN B CA 113 ASN B CA 1 ATOM 2249 C C . ASN B 2 113 ? -19.513 -6.714 14.239 1.00 87.87 ? 113 ASN B C 113 ASN B C 1 ATOM 2250 O O . ASN B 2 113 ? -19.926 -7.788 13.800 1.00 87.87 ? 113 ASN B O 113 ASN B O 1 ATOM 2251 C CB . ASN B 2 113 ? -20.844 -4.630 13.822 1.00 87.87 ? 113 ASN B CB 113 ASN B CB 1 ATOM 2252 C CG . ASN B 2 113 ? -22.019 -3.777 14.259 1.00 87.87 ? 113 ASN B CG 113 ASN B CG 1 ATOM 2253 O OD1 . ASN B 2 113 ? -22.879 -4.227 15.021 1.00 87.87 ? 113 ASN B OD1 113 ASN B OD1 1 ATOM 2254 N ND2 . ASN B 2 113 ? -22.065 -2.540 13.780 1.00 87.87 ? 113 ASN B ND2 113 ASN B ND2 1 ATOM 2255 N N . LEU B 2 114 ? -18.315 -6.376 14.311 1.00 89.44 ? 114 LEU B N 114 LEU B N 1 ATOM 2256 C CA . LEU B 2 114 ? -17.298 -7.262 13.755 1.00 89.44 ? 114 LEU B CA 114 LEU B CA 1 ATOM 2257 C C . LEU B 2 114 ? -17.221 -8.565 14.544 1.00 89.44 ? 114 LEU B C 114 LEU B C 1 ATOM 2258 O O . LEU B 2 114 ? -17.095 -9.643 13.959 1.00 89.44 ? 114 LEU B O 114 LEU B O 1 ATOM 2259 C CB . LEU B 2 114 ? -15.931 -6.573 13.750 1.00 89.44 ? 114 LEU B CB 114 LEU B CB 1 ATOM 2260 C CG . LEU B 2 114 ? -15.714 -5.505 12.677 1.00 89.44 ? 114 LEU B CG 114 LEU B CG 1 ATOM 2261 C CD1 . LEU B 2 114 ? -14.414 -4.750 12.936 1.00 89.44 ? 114 LEU B CD1 114 LEU B CD1 1 ATOM 2262 C CD2 . LEU B 2 114 ? -15.703 -6.137 11.289 1.00 89.44 ? 114 LEU B CD2 114 LEU B CD2 1 ATOM 2263 N N . LEU B 2 115 ? -17.332 -8.462 15.840 1.00 88.92 ? 115 LEU B N 115 LEU B N 1 ATOM 2264 C CA . LEU B 2 115 ? -17.316 -9.635 16.708 1.00 88.92 ? 115 LEU B CA 115 LEU B CA 1 ATOM 2265 C C . LEU B 2 115 ? -18.534 -10.516 16.454 1.00 88.92 ? 115 LEU B C 115 LEU B C 1 ATOM 2266 O O . LEU B 2 115 ? -18.418 -11.742 16.398 1.00 88.92 ? 115 LEU B O 115 LEU B O 1 ATOM 2267 C CB . LEU B 2 115 ? -17.275 -9.212 18.179 1.00 88.92 ? 115 LEU B CB 115 LEU B CB 1 ATOM 2268 C CG . LEU B 2 115 ? -15.945 -8.653 18.687 1.00 88.92 ? 115 LEU B CG 115 LEU B CG 1 ATOM 2269 C CD1 . LEU B 2 115 ? -16.115 -8.068 20.085 1.00 88.92 ? 115 LEU B CD1 115 LEU B CD1 1 ATOM 2270 C CD2 . LEU B 2 115 ? -14.872 -9.737 18.682 1.00 88.92 ? 115 LEU B CD2 115 LEU B CD2 1 ATOM 2271 N N . ASN B 2 116 ? -19.631 -9.841 16.231 1.00 88.42 ? 116 ASN B N 116 ASN B N 1 ATOM 2272 C CA . ASN B 2 116 ? -20.889 -10.546 16.012 1.00 88.42 ? 116 ASN B CA 116 ASN B CA 1 ATOM 2273 C C . ASN B 2 116 ? -20.914 -11.240 14.654 1.00 88.42 ? 116 ASN B C 116 ASN B C 1 ATOM 2274 O O . ASN B 2 116 ? -21.389 -12.372 14.539 1.00 88.42 ? 116 ASN B O 116 ASN B O 1 ATOM 2275 C CB . ASN B 2 116 ? -22.072 -9.583 16.138 1.00 88.42 ? 116 ASN B CB 116 ASN B CB 1 ATOM 2276 C CG . ASN B 2 116 ? -22.309 -9.132 17.566 1.00 88.42 ? 116 ASN B CG 116 ASN B CG 1 ATOM 2277 O OD1 . ASN B 2 116 ? -21.814 -9.747 18.514 1.00 88.42 ? 116 ASN B OD1 116 ASN B OD1 1 ATOM 2278 N ND2 . ASN B 2 116 ? -23.066 -8.054 17.729 1.00 88.42 ? 116 ASN B ND2 116 ASN B ND2 1 ATOM 2279 N N . TRP B 2 117 ? -20.333 -10.603 13.663 1.00 87.72 ? 117 TRP B N 117 TRP B N 1 ATOM 2280 C CA . TRP B 2 117 ? -20.379 -11.117 12.298 1.00 87.72 ? 117 TRP B CA 117 TRP B CA 1 ATOM 2281 C C . TRP B 2 117 ? -19.384 -12.258 12.111 1.00 87.72 ? 117 TRP B C 117 TRP B C 1 ATOM 2282 O O . TRP B 2 117 ? -19.581 -13.128 11.260 1.00 87.72 ? 117 TRP B O 117 TRP B O 1 ATOM 2283 C CB . TRP B 2 117 ? -20.088 -10.000 11.292 1.00 87.72 ? 117 TRP B CB 117 TRP B CB 1 ATOM 2284 C CG . TRP B 2 117 ? -21.128 -8.920 11.263 1.00 87.72 ? 117 TRP B CG 117 TRP B CG 1 ATOM 2285 C CD1 . TRP B 2 117 ? -22.439 -9.029 11.636 1.00 87.72 ? 117 TRP B CD1 117 TRP B CD1 1 ATOM 2286 C CD2 . TRP B 2 117 ? -20.944 -7.568 10.834 1.00 87.72 ? 117 TRP B CD2 117 TRP B CD2 1 ATOM 2287 N NE1 . TRP B 2 117 ? -23.081 -7.824 11.464 1.00 87.72 ? 117 TRP B NE1 117 TRP B NE1 1 ATOM 2288 C CE2 . TRP B 2 117 ? -22.187 -6.912 10.974 1.00 87.72 ? 117 TRP B CE2 117 TRP B CE2 1 ATOM 2289 C CE3 . TRP B 2 117 ? -19.847 -6.846 10.345 1.00 87.72 ? 117 TRP B CE3 117 TRP B CE3 1 ATOM 2290 C CZ2 . TRP B 2 117 ? -22.362 -5.566 10.641 1.00 87.72 ? 117 TRP B CZ2 117 TRP B CZ2 1 ATOM 2291 C CZ3 . TRP B 2 117 ? -20.024 -5.507 10.015 1.00 87.72 ? 117 TRP B CZ3 117 TRP B CZ3 1 ATOM 2292 C CH2 . TRP B 2 117 ? -21.273 -4.883 10.165 1.00 87.72 ? 117 TRP B CH2 117 TRP B CH2 1 ATOM 2293 N N . ASN B 2 118 ? -18.352 -12.272 12.977 1.00 86.56 ? 118 ASN B N 118 ASN B N 1 ATOM 2294 C CA . ASN B 2 118 ? -17.269 -13.239 12.836 1.00 86.56 ? 118 ASN B CA 118 ASN B CA 1 ATOM 2295 C C . ASN B 2 118 ? -17.138 -14.119 14.076 1.00 86.56 ? 118 ASN B C 118 ASN B C 1 ATOM 2296 O O . ASN B 2 118 ? -16.192 -13.970 14.851 1.00 86.56 ? 118 ASN B O 118 ASN B O 1 ATOM 2297 C CB . ASN B 2 118 ? -15.947 -12.526 12.549 1.00 86.56 ? 118 ASN B CB 118 ASN B CB 1 ATOM 2298 C CG . ASN B 2 118 ? -15.964 -11.771 11.234 1.00 86.56 ? 118 ASN B CG 118 ASN B CG 1 ATOM 2299 O OD1 . ASN B 2 118 ? -15.826 -12.365 10.161 1.00 86.56 ? 118 ASN B OD1 118 ASN B OD1 1 ATOM 2300 N ND2 . ASN B 2 118 ? -16.134 -10.457 11.307 1.00 86.56 ? 118 ASN B ND2 118 ASN B ND2 1 ATOM 2301 N N . LYS B 2 119 ? -18.038 -15.027 14.356 1.00 79.82 ? 119 LYS B N 119 LYS B N 1 ATOM 2302 C CA . LYS B 2 119 ? -18.137 -15.812 15.583 1.00 79.82 ? 119 LYS B CA 119 LYS B CA 1 ATOM 2303 C C . LYS B 2 119 ? -17.272 -17.067 15.505 1.00 79.82 ? 119 LYS B C 119 LYS B C 1 ATOM 2304 O O . LYS B 2 119 ? -17.121 -17.786 16.494 1.00 79.82 ? 119 LYS B O 119 LYS B O 1 ATOM 2305 C CB . LYS B 2 119 ? -19.592 -16.194 15.860 1.00 79.82 ? 119 LYS B CB 119 LYS B CB 1 ATOM 2306 C CG . LYS B 2 119 ? -20.488 -15.013 16.201 1.00 79.82 ? 119 LYS B CG 119 LYS B CG 1 ATOM 2307 C CD . LYS B 2 119 ? -21.916 -15.459 16.488 1.00 79.82 ? 119 LYS B CD 119 LYS B CD 1 ATOM 2308 C CE . LYS B 2 119 ? -22.827 -14.273 16.773 1.00 79.82 ? 119 LYS B CE 119 LYS B CE 1 ATOM 2309 N NZ . LYS B 2 119 ? -24.232 -14.705 17.038 1.00 79.82 ? 119 LYS B NZ 119 LYS B NZ 1 ATOM 2310 N N . GLY B 2 120 ? -16.438 -17.167 14.513 1.00 71.76 ? 120 GLY B N 120 GLY B N 1 ATOM 2311 C CA . GLY B 2 120 ? -15.651 -18.383 14.386 1.00 71.76 ? 120 GLY B CA 120 GLY B CA 1 ATOM 2312 C C . GLY B 2 120 ? -14.421 -18.393 15.273 1.00 71.76 ? 120 GLY B C 120 GLY B C 1 ATOM 2313 O O . GLY B 2 120 ? -13.681 -17.409 15.329 1.00 71.76 ? 120 GLY B O 120 GLY B O 1 ATOM 2314 N N . LYS B 2 121 ? -14.305 -19.300 16.272 1.00 62.24 ? 121 LYS B N 121 LYS B N 1 ATOM 2315 C CA . LYS B 2 121 ? -13.271 -19.426 17.295 1.00 62.24 ? 121 LYS B CA 121 LYS B CA 1 ATOM 2316 C C . LYS B 2 121 ? -11.907 -19.698 16.667 1.00 62.24 ? 121 LYS B C 121 LYS B C 1 ATOM 2317 O O . LYS B 2 121 ? -10.882 -19.230 17.168 1.00 62.24 ? 121 LYS B O 121 LYS B O 1 ATOM 2318 C CB . LYS B 2 121 ? -13.624 -20.539 18.282 1.00 62.24 ? 121 LYS B CB 121 LYS B CB 1 ATOM 2319 C CG . LYS B 2 121 ? -14.748 -20.180 19.243 1.00 62.24 ? 121 LYS B CG 121 LYS B CG 1 ATOM 2320 C CD . LYS B 2 121 ? -14.972 -21.277 20.276 1.00 62.24 ? 121 LYS B CD 121 LYS B CD 1 ATOM 2321 C CE . LYS B 2 121 ? -16.138 -20.947 21.199 1.00 62.24 ? 121 LYS B CE 121 LYS B CE 1 ATOM 2322 N NZ . LYS B 2 121 ? -16.359 -22.018 22.216 1.00 62.24 ? 121 LYS B NZ 121 LYS B NZ 1 ATOM 2323 N N . ASP B 2 122 ? -11.855 -20.288 15.449 1.00 66.96 ? 122 ASP B N 122 ASP B N 1 ATOM 2324 C CA . ASP B 2 122 ? -10.593 -20.693 14.838 1.00 66.96 ? 122 ASP B CA 122 ASP B CA 1 ATOM 2325 C C . ASP B 2 122 ? -10.219 -19.765 13.684 1.00 66.96 ? 122 ASP B C 122 ASP B C 1 ATOM 2326 O O . ASP B 2 122 ? -9.430 -20.136 12.812 1.00 66.96 ? 122 ASP B O 122 ASP B O 1 ATOM 2327 C CB . ASP B 2 122 ? -10.674 -22.139 14.344 1.00 66.96 ? 122 ASP B CB 122 ASP B CB 1 ATOM 2328 C CG . ASP B 2 122 ? -10.590 -23.155 15.470 1.00 66.96 ? 122 ASP B CG 122 ASP B CG 1 ATOM 2329 O OD1 . ASP B 2 122 ? -10.140 -22.800 16.580 1.00 66.96 ? 122 ASP B OD1 122 ASP B OD1 1 ATOM 2330 O OD2 . ASP B 2 122 ? -10.975 -24.323 15.243 1.00 66.96 ? 122 ASP B OD2 122 ASP B OD2 1 ATOM 2331 N N . SER B 2 123 ? -10.640 -18.518 13.870 1.00 73.19 ? 123 SER B N 123 SER B N 1 ATOM 2332 C CA . SER B 2 123 ? -10.411 -17.642 12.725 1.00 73.19 ? 123 SER B CA 123 SER B CA 1 ATOM 2333 C C . SER B 2 123 ? -8.991 -17.088 12.728 1.00 73.19 ? 123 SER B C 123 SER B C 1 ATOM 2334 O O . SER B 2 123 ? -8.441 -16.780 13.788 1.00 73.19 ? 123 SER B O 123 SER B O 1 ATOM 2335 C CB . SER B 2 123 ? -11.417 -16.490 12.723 1.00 73.19 ? 123 SER B CB 123 SER B CB 1 ATOM 2336 O OG . SER B 2 123 ? -11.046 -15.496 13.663 1.00 73.19 ? 123 SER B OG 123 SER B OG 1 ATOM 2337 N N . THR B 2 124 ? -8.230 -17.246 11.707 1.00 83.05 ? 124 THR B N 124 THR B N 1 ATOM 2338 C CA . THR B 2 124 ? -6.898 -16.703 11.462 1.00 83.05 ? 124 THR B CA 124 THR B CA 1 ATOM 2339 C C . THR B 2 124 ? -6.914 -15.179 11.536 1.00 83.05 ? 124 THR B C 124 THR B C 1 ATOM 2340 O O . THR B 2 124 ? -5.858 -14.543 11.574 1.00 83.05 ? 124 THR B O 124 THR B O 1 ATOM 2341 C CB . THR B 2 124 ? -6.358 -17.147 10.090 1.00 83.05 ? 124 THR B CB 124 THR B CB 1 ATOM 2342 O OG1 . THR B 2 124 ? -7.294 -16.775 9.071 1.00 83.05 ? 124 THR B OG1 124 THR B OG1 1 ATOM 2343 C CG2 . THR B 2 124 ? -6.147 -18.657 10.044 1.00 83.05 ? 124 THR B CG2 124 THR B CG2 1 ATOM 2344 N N . PHE B 2 125 ? -8.184 -14.575 11.685 1.00 89.05 ? 125 PHE B N 125 PHE B N 1 ATOM 2345 C CA . PHE B 2 125 ? -8.337 -13.125 11.642 1.00 89.05 ? 125 PHE B CA 125 PHE B CA 1 ATOM 2346 C C . PHE B 2 125 ? -8.689 -12.577 13.019 1.00 89.05 ? 125 PHE B C 125 PHE B C 1 ATOM 2347 O O . PHE B 2 125 ? -9.336 -11.534 13.131 1.00 89.05 ? 125 PHE B O 125 PHE B O 1 ATOM 2348 C CB . PHE B 2 125 ? -9.413 -12.727 10.627 1.00 89.05 ? 125 PHE B CB 125 PHE B CB 1 ATOM 2349 C CG . PHE B 2 125 ? -9.138 -13.210 9.229 1.00 89.05 ? 125 PHE B CG 125 PHE B CG 1 ATOM 2350 C CD1 . PHE B 2 125 ? -8.148 -12.616 8.456 1.00 89.05 ? 125 PHE B CD1 125 PHE B CD1 1 ATOM 2351 C CD2 . PHE B 2 125 ? -9.869 -14.259 8.687 1.00 89.05 ? 125 PHE B CD2 125 PHE B CD2 1 ATOM 2352 C CE1 . PHE B 2 125 ? -7.890 -13.060 7.161 1.00 89.05 ? 125 PHE B CE1 125 PHE B CE1 1 ATOM 2353 C CE2 . PHE B 2 125 ? -9.618 -14.709 7.394 1.00 89.05 ? 125 PHE B CE2 125 PHE B CE2 1 ATOM 2354 C CZ . PHE B 2 125 ? -8.629 -14.108 6.632 1.00 89.05 ? 125 PHE B CZ 125 PHE B CZ 1 ATOM 2355 N N . ALA B 2 126 ? -8.401 -13.305 14.063 1.00 89.32 ? 126 ALA B N 126 ALA B N 1 ATOM 2356 C CA . ALA B 2 126 ? -8.800 -12.985 15.432 1.00 89.32 ? 126 ALA B CA 126 ALA B CA 1 ATOM 2357 C C . ALA B 2 126 ? -8.348 -11.580 15.820 1.00 89.32 ? 126 ALA B C 126 ALA B C 1 ATOM 2358 O O . ALA B 2 126 ? -9.119 -10.811 16.400 1.00 89.32 ? 126 ALA B O 126 ALA B O 1 ATOM 2359 C CB . ALA B 2 126 ? -8.230 -14.012 16.406 1.00 89.32 ? 126 ALA B CB 126 ALA B CB 1 ATOM 2360 N N . SER B 2 127 ? -7.107 -11.180 15.486 1.00 92.26 ? 127 SER B N 127 SER B N 1 ATOM 2361 C CA . SER B 2 127 ? -6.564 -9.880 15.867 1.00 92.26 ? 127 SER B CA 127 SER B CA 1 ATOM 2362 C C . SER B 2 127 ? -7.293 -8.746 15.153 1.00 92.26 ? 127 SER B C 127 SER B C 1 ATOM 2363 O O . SER B 2 127 ? -7.581 -7.710 15.756 1.00 92.26 ? 127 SER B O 127 SER B O 1 ATOM 2364 C CB . SER B 2 127 ? -5.068 -9.811 15.554 1.00 92.26 ? 127 SER B CB 127 SER B CB 1 ATOM 2365 O OG . SER B 2 127 ? -4.346 -10.738 16.346 1.00 92.26 ? 127 SER B OG 127 SER B OG 1 ATOM 2366 N N . SER B 2 128 ? -7.581 -8.977 13.934 1.00 91.75 ? 128 SER B N 128 SER B N 1 ATOM 2367 C CA . SER B 2 128 ? -8.284 -7.971 13.144 1.00 91.75 ? 128 SER B CA 128 SER B CA 1 ATOM 2368 C C . SER B 2 128 ? -9.719 -7.792 13.628 1.00 91.75 ? 128 SER B C 128 SER B C 1 ATOM 2369 O O . SER B 2 128 ? -10.209 -6.665 13.730 1.00 91.75 ? 128 SER B O 128 SER B O 1 ATOM 2370 C CB . SER B 2 128 ? -8.281 -8.354 11.663 1.00 91.75 ? 128 SER B CB 128 SER B CB 1 ATOM 2371 O OG . SER B 2 128 ? -6.955 -8.437 11.168 1.00 91.75 ? 128 SER B OG 128 SER B OG 1 ATOM 2372 N N . VAL B 2 129 ? -10.384 -8.875 14.020 1.00 91.15 ? 129 VAL B N 129 VAL B N 1 ATOM 2373 C CA . VAL B 2 129 ? -11.786 -8.869 14.423 1.00 91.15 ? 129 VAL B CA 129 VAL B CA 1 ATOM 2374 C C . VAL B 2 129 ? -11.923 -8.247 15.811 1.00 91.15 ? 129 VAL B C 129 VAL B C 1 ATOM 2375 O O . VAL B 2 129 ? -12.781 -7.390 16.033 1.00 91.15 ? 129 VAL B O 129 VAL B O 1 ATOM 2376 C CB . VAL B 2 129 ? -12.385 -10.294 14.416 1.00 91.15 ? 129 VAL B CB 129 VAL B CB 1 ATOM 2377 C CG1 . VAL B 2 129 ? -13.793 -10.291 15.008 1.00 91.15 ? 129 VAL B CG1 129 VAL B CG1 1 ATOM 2378 C CG2 . VAL B 2 129 ? -12.398 -10.859 12.997 1.00 91.15 ? 129 VAL B CG2 129 VAL B CG2 1 ATOM 2379 N N . THR B 2 130 ? -11.069 -8.642 16.751 1.00 90.66 ? 130 THR B N 130 THR B N 1 ATOM 2380 C CA . THR B 2 130 ? -11.144 -8.124 18.113 1.00 90.66 ? 130 THR B CA 130 THR B CA 1 ATOM 2381 C C . THR B 2 130 ? -10.571 -6.712 18.187 1.00 90.66 ? 130 THR B C 130 THR B C 1 ATOM 2382 O O . THR B 2 130 ? -10.960 -5.923 19.050 1.00 90.66 ? 130 THR B O 130 THR B O 1 ATOM 2383 C CB . THR B 2 130 ? -10.394 -9.038 19.100 1.00 90.66 ? 130 THR B CB 130 THR B CB 1 ATOM 2384 O OG1 . THR B 2 130 ? -9.016 -9.117 18.716 1.00 90.66 ? 130 THR B OG1 130 THR B OG1 1 ATOM 2385 C CG2 . THR B 2 130 ? -10.989 -10.442 19.110 1.00 90.66 ? 130 THR B CG2 130 THR B CG2 1 ATOM 2386 N N . GLY B 2 131 ? -9.711 -6.392 17.259 1.00 90.38 ? 131 GLY B N 131 GLY B N 1 ATOM 2387 C CA . GLY B 2 131 ? -9.050 -5.096 17.264 1.00 90.38 ? 131 GLY B CA 131 GLY B CA 1 ATOM 2388 C C . GLY B 2 131 ? -7.882 -5.026 18.229 1.00 90.38 ? 131 GLY B C 131 GLY B C 1 ATOM 2389 O O . GLY B 2 131 ? -7.318 -3.953 18.452 1.00 90.38 ? 131 GLY B O 131 GLY B O 1 ATOM 2390 N N . THR B 2 132 ? -7.559 -6.148 18.854 1.00 92.74 ? 132 THR B N 132 THR B N 1 ATOM 2391 C CA . THR B 2 132 ? -6.434 -6.238 19.779 1.00 92.74 ? 132 THR B CA 132 THR B CA 1 ATOM 2392 C C . THR B 2 132 ? -5.266 -6.982 19.138 1.00 92.74 ? 132 THR B C 132 THR B C 1 ATOM 2393 O O . THR B 2 132 ? -5.452 -8.042 18.537 1.00 92.74 ? 132 THR B O 132 THR B O 1 ATOM 2394 C CB . THR B 2 132 ? -6.841 -6.944 21.085 1.00 92.74 ? 132 THR B CB 132 THR B CB 1 ATOM 2395 O OG1 . THR B 2 132 ? -7.360 -8.244 20.778 1.00 92.74 ? 132 THR B OG1 132 THR B OG1 1 ATOM 2396 C CG2 . THR B 2 132 ? -7.907 -6.149 21.832 1.00 92.74 ? 132 THR B CG2 132 THR B CG2 1 ATOM 2397 N N . LEU B 2 133 ? -4.063 -6.405 19.268 1.00 94.00 ? 133 LEU B N 133 LEU B N 1 ATOM 2398 C CA . LEU B 2 133 ? -2.874 -6.968 18.638 1.00 94.00 ? 133 LEU B CA 133 LEU B CA 1 ATOM 2399 C C . LEU B 2 133 ? -2.254 -8.050 19.516 1.00 94.00 ? 133 LEU B C 133 LEU B C 1 ATOM 2400 O O . LEU B 2 133 ? -2.174 -7.894 20.737 1.00 94.00 ? 133 LEU B O 133 LEU B O 1 ATOM 2401 C CB . LEU B 2 133 ? -1.845 -5.870 18.358 1.00 94.00 ? 133 LEU B CB 133 LEU B CB 1 ATOM 2402 C CG . LEU B 2 133 ? -2.332 -4.680 17.529 1.00 94.00 ? 133 LEU B CG 133 LEU B CG 1 ATOM 2403 C CD1 . LEU B 2 133 ? -1.258 -3.599 17.473 1.00 94.00 ? 133 LEU B CD1 133 LEU B CD1 1 ATOM 2404 C CD2 . LEU B 2 133 ? -2.721 -5.129 16.125 1.00 94.00 ? 133 LEU B CD2 133 LEU B CD2 1 ATOM 2405 N N . ARG B 2 134 ? -1.812 -9.172 18.883 1.00 93.23 ? 134 ARG B N 134 ARG B N 1 ATOM 2406 C CA . ARG B 2 134 ? -1.210 -10.304 19.578 1.00 93.23 ? 134 ARG B CA 134 ARG B CA 1 ATOM 2407 C C . ARG B 2 134 ? 0.265 -10.447 19.218 1.00 93.23 ? 134 ARG B C 134 ARG B C 1 ATOM 2408 O O . ARG B 2 134 ? 0.696 -9.995 18.155 1.00 93.23 ? 134 ARG B O 134 ARG B O 1 ATOM 2409 C CB . ARG B 2 134 ? -1.957 -11.598 19.249 1.00 93.23 ? 134 ARG B CB 134 ARG B CB 1 ATOM 2410 C CG . ARG B 2 134 ? -3.411 -11.600 19.694 1.00 93.23 ? 134 ARG B CG 134 ARG B CG 1 ATOM 2411 C CD . ARG B 2 134 ? -4.098 -12.919 19.372 1.00 93.23 ? 134 ARG B CD 134 ARG B CD 1 ATOM 2412 N NE . ARG B 2 134 ? -4.272 -13.100 17.934 1.00 93.23 ? 134 ARG B NE 134 ARG B NE 1 ATOM 2413 C CZ . ARG B 2 134 ? -4.917 -14.117 17.370 1.00 93.23 ? 134 ARG B CZ 134 ARG B CZ 1 ATOM 2414 N NH1 . ARG B 2 134 ? -5.466 -15.069 18.116 1.00 93.23 ? 134 ARG B NH1 134 ARG B NH1 1 ATOM 2415 N NH2 . ARG B 2 134 ? -5.016 -14.183 16.050 1.00 93.23 ? 134 ARG B NH2 134 ARG B NH2 1 ATOM 2416 N N . PRO B 2 135 ? 0.920 -11.061 20.141 1.00 91.79 ? 135 PRO B N 135 PRO B N 1 ATOM 2417 C CA . PRO B 2 135 ? 2.339 -11.287 19.853 1.00 91.79 ? 135 PRO B CA 135 PRO B CA 1 ATOM 2418 C C . PRO B 2 135 ? 2.560 -12.084 18.569 1.00 91.79 ? 135 PRO B C 135 PRO B C 1 ATOM 2419 O O . PRO B 2 135 ? 1.879 -13.085 18.334 1.00 91.79 ? 135 PRO B O 135 PRO B O 1 ATOM 2420 C CB . PRO B 2 135 ? 2.826 -12.072 21.074 1.00 91.79 ? 135 PRO B CB 135 PRO B CB 1 ATOM 2421 C CG . PRO B 2 135 ? 1.848 -11.742 22.155 1.00 91.79 ? 135 PRO B CG 135 PRO B CG 1 ATOM 2422 C CD . PRO B 2 135 ? 0.502 -11.519 21.529 1.00 91.79 ? 135 PRO B CD 135 PRO B CD 1 ATOM 2423 N N . GLY B 2 136 ? 3.441 -11.663 17.706 1.00 92.39 ? 136 GLY B N 136 GLY B N 1 ATOM 2424 C CA . GLY B 2 136 ? 3.767 -12.304 16.442 1.00 92.39 ? 136 GLY B CA 136 GLY B CA 1 ATOM 2425 C C . GLY B 2 136 ? 3.037 -11.696 15.259 1.00 92.39 ? 136 GLY B C 136 GLY B C 1 ATOM 2426 O O . GLY B 2 136 ? 3.315 -12.039 14.108 1.00 92.39 ? 136 GLY B O 136 GLY B O 1 ATOM 2427 N N . ASP B 2 137 ? 2.123 -10.796 15.517 1.00 95.21 ? 137 ASP B N 137 ASP B N 1 ATOM 2428 C CA . ASP B 2 137 ? 1.348 -10.147 14.464 1.00 95.21 ? 137 ASP B CA 137 ASP B CA 1 ATOM 2429 C C . ASP B 2 137 ? 2.220 -9.199 13.645 1.00 95.21 ? 137 ASP B C 137 ASP B C 1 ATOM 2430 O O . ASP B 2 137 ? 3.064 -8.490 14.197 1.00 95.21 ? 137 ASP B O 137 ASP B O 1 ATOM 2431 C CB . ASP B 2 137 ? 0.162 -9.386 15.062 1.00 95.21 ? 137 ASP B CB 137 ASP B CB 1 ATOM 2432 C CG . ASP B 2 137 ? -0.971 -10.300 15.495 1.00 95.21 ? 137 ASP B CG 137 ASP B CG 1 ATOM 2433 O OD1 . ASP B 2 137 ? -0.926 -11.512 15.194 1.00 95.21 ? 137 ASP B OD1 137 ASP B OD1 1 ATOM 2434 O OD2 . ASP B 2 137 ? -1.919 -9.802 16.140 1.00 95.21 ? 137 ASP B OD2 137 ASP B OD2 1 ATOM 2435 N N . LEU B 2 138 ? 2.045 -9.274 12.369 1.00 96.16 ? 138 LEU B N 138 LEU B N 1 ATOM 2436 C CA . LEU B 2 138 ? 2.591 -8.253 11.481 1.00 96.16 ? 138 LEU B CA 138 LEU B CA 1 ATOM 2437 C C . LEU B 2 138 ? 1.617 -7.091 11.325 1.00 96.16 ? 138 LEU B C 138 LEU B C 1 ATOM 2438 O O . LEU B 2 138 ? 0.516 -7.264 10.797 1.00 96.16 ? 138 LEU B O 138 LEU B O 1 ATOM 2439 C CB . LEU B 2 138 ? 2.914 -8.853 10.110 1.00 96.16 ? 138 LEU B CB 138 LEU B CB 1 ATOM 2440 C CG . LEU B 2 138 ? 3.936 -9.990 10.090 1.00 96.16 ? 138 LEU B CG 138 LEU B CG 1 ATOM 2441 C CD1 . LEU B 2 138 ? 4.163 -10.474 8.662 1.00 96.16 ? 138 LEU B CD1 138 LEU B CD1 1 ATOM 2442 C CD2 . LEU B 2 138 ? 5.248 -9.542 10.724 1.00 96.16 ? 138 LEU B CD2 138 LEU B CD2 1 ATOM 2443 N N . VAL B 2 139 ? 2.036 -5.952 11.822 1.00 96.44 ? 139 VAL B N 139 VAL B N 1 ATOM 2444 C CA . VAL B 2 139 ? 1.173 -4.776 11.810 1.00 96.44 ? 139 VAL B CA 139 VAL B CA 1 ATOM 2445 C C . VAL B 2 139 ? 1.653 -3.794 10.743 1.00 96.44 ? 139 VAL B C 139 VAL B C 1 ATOM 2446 O O . VAL B 2 139 ? 2.743 -3.229 10.855 1.00 96.44 ? 139 VAL B O 139 VAL B O 1 ATOM 2447 C CB . VAL B 2 139 ? 1.136 -4.085 13.191 1.00 96.44 ? 139 VAL B CB 139 VAL B CB 1 ATOM 2448 C CG1 . VAL B 2 139 ? 0.225 -2.859 13.157 1.00 96.44 ? 139 VAL B CG1 139 VAL B CG1 1 ATOM 2449 C CG2 . VAL B 2 139 ? 0.674 -5.067 14.266 1.00 96.44 ? 139 VAL B CG2 139 VAL B CG2 1 ATOM 2450 N N . LYS B 2 140 ? 0.849 -3.632 9.683 1.00 97.05 ? 140 LYS B N 140 LYS B N 1 ATOM 2451 C CA . LYS B 2 140 ? 1.145 -2.686 8.612 1.00 97.05 ? 140 LYS B CA 140 LYS B CA 1 ATOM 2452 C C . LYS B 2 140 ? 0.409 -1.366 8.825 1.00 97.05 ? 140 LYS B C 140 LYS B C 1 ATOM 2453 O O . LYS B 2 140 ? -0.822 -1.319 8.765 1.00 97.05 ? 140 LYS B O 140 LYS B O 1 ATOM 2454 C CB . LYS B 2 140 ? 0.773 -3.279 7.252 1.00 97.05 ? 140 LYS B CB 140 LYS B CB 1 ATOM 2455 C CG . LYS B 2 140 ? 1.463 -4.600 6.944 1.00 97.05 ? 140 LYS B CG 140 LYS B CG 1 ATOM 2456 C CD . LYS B 2 140 ? 0.880 -5.258 5.700 1.00 97.05 ? 140 LYS B CD 140 LYS B CD 1 ATOM 2457 C CE . LYS B 2 140 ? -0.547 -5.734 5.934 1.00 97.05 ? 140 LYS B CE 140 LYS B CE 1 ATOM 2458 N NZ . LYS B 2 140 ? -0.591 -7.170 6.343 1.00 97.05 ? 140 LYS B NZ 140 LYS B NZ 1 ATOM 2459 N N . ILE B 2 141 ? 1.180 -0.345 9.088 1.00 96.84 ? 141 ILE B N 141 ILE B N 1 ATOM 2460 C CA . ILE B 2 141 ? 0.619 0.983 9.310 1.00 96.84 ? 141 ILE B CA 141 ILE B CA 1 ATOM 2461 C C . ILE B 2 141 ? 0.729 1.810 8.031 1.00 96.84 ? 141 ILE B C 141 ILE B C 1 ATOM 2462 O O . ILE B 2 141 ? 1.832 2.054 7.535 1.00 96.84 ? 141 ILE B O 141 ILE B O 1 ATOM 2463 C CB . ILE B 2 141 ? 1.326 1.707 10.478 1.00 96.84 ? 141 ILE B CB 141 ILE B CB 1 ATOM 2464 C CG1 . ILE B 2 141 ? 1.290 0.841 11.743 1.00 96.84 ? 141 ILE B CG1 141 ILE B CG1 1 ATOM 2465 C CG2 . ILE B 2 141 ? 0.686 3.074 10.732 1.00 96.84 ? 141 ILE B CG2 141 ILE B CG2 1 ATOM 2466 C CD1 . ILE B 2 141 ? 2.230 1.313 12.843 1.00 96.84 ? 141 ILE B CD1 141 ILE B CD1 1 ATOM 2467 N N . THR B 2 142 ? -0.443 2.247 7.531 1.00 96.06 ? 142 THR B N 142 THR B N 1 ATOM 2468 C CA . THR B 2 142 ? -0.468 3.039 6.306 1.00 96.06 ? 142 THR B CA 142 THR B CA 1 ATOM 2469 C C . THR B 2 142 ? -1.148 4.384 6.545 1.00 96.06 ? 142 THR B C 142 THR B C 1 ATOM 2470 O O . THR B 2 142 ? -2.247 4.440 7.102 1.00 96.06 ? 142 THR B O 142 THR B O 1 ATOM 2471 C CB . THR B 2 142 ? -1.191 2.290 5.172 1.00 96.06 ? 142 THR B CB 142 THR B CB 1 ATOM 2472 O OG1 . THR B 2 142 ? -0.560 1.019 4.968 1.00 96.06 ? 142 THR B OG1 142 THR B OG1 1 ATOM 2473 C CG2 . THR B 2 142 ? -1.141 3.083 3.870 1.00 96.06 ? 142 THR B CG2 142 THR B CG2 1 ATOM 2474 N N . LEU B 2 143 ? -0.489 5.396 6.186 1.00 95.19 ? 143 LEU B N 143 LEU B N 1 ATOM 2475 C CA . LEU B 2 143 ? -1.069 6.731 6.281 1.00 95.19 ? 143 LEU B CA 143 LEU B CA 1 ATOM 2476 C C . LEU B 2 143 ? -0.452 7.666 5.246 1.00 95.19 ? 143 LEU B C 143 LEU B C 1 ATOM 2477 O O . LEU B 2 143 ? 0.623 7.385 4.712 1.00 95.19 ? 143 LEU B O 143 LEU B O 1 ATOM 2478 C CB . LEU B 2 143 ? -0.869 7.305 7.686 1.00 95.19 ? 143 LEU B CB 143 LEU B CB 1 ATOM 2479 C CG . LEU B 2 143 ? 0.576 7.427 8.170 1.00 95.19 ? 143 LEU B CG 143 LEU B CG 1 ATOM 2480 C CD1 . LEU B 2 143 ? 1.184 8.744 7.697 1.00 95.19 ? 143 LEU B CD1 143 LEU B CD1 1 ATOM 2481 C CD2 . LEU B 2 143 ? 0.644 7.316 9.689 1.00 95.19 ? 143 LEU B CD2 143 LEU B CD2 1 ATOM 2482 N N . GLY B 2 144 ? -1.224 8.787 4.924 1.00 93.98 ? 144 GLY B N 144 GLY B N 1 ATOM 2483 C CA . GLY B 2 144 ? -0.768 9.738 3.923 1.00 93.98 ? 144 GLY B CA 144 GLY B CA 1 ATOM 2484 C C . GLY B 2 144 ? -1.291 11.143 4.154 1.00 93.98 ? 144 GLY B C 144 GLY B C 1 ATOM 2485 O O . GLY B 2 144 ? -2.402 11.323 4.656 1.00 93.98 ? 144 GLY B O 144 GLY B O 1 ATOM 2486 N N . VAL B 2 145 ? -0.470 12.116 3.736 1.00 93.89 ? 145 VAL B N 145 VAL B N 1 ATOM 2487 C CA . VAL B 2 145 ? -0.825 13.523 3.885 1.00 93.89 ? 145 VAL B CA 145 VAL B CA 1 ATOM 2488 C C . VAL B 2 145 ? -0.585 14.259 2.569 1.00 93.89 ? 145 VAL B C 145 VAL B C 1 ATOM 2489 O O . VAL B 2 145 ? 0.306 13.892 1.799 1.00 93.89 ? 145 VAL B O 145 VAL B O 1 ATOM 2490 C CB . VAL B 2 145 ? -0.025 14.193 5.025 1.00 93.89 ? 145 VAL B CB 145 VAL B CB 1 ATOM 2491 C CG1 . VAL B 2 145 ? -0.357 15.681 5.115 1.00 93.89 ? 145 VAL B CG1 145 VAL B CG1 1 ATOM 2492 C CG2 . VAL B 2 145 ? -0.307 13.498 6.355 1.00 93.89 ? 145 VAL B CG2 145 VAL B CG2 1 ATOM 2493 N N . HIS B 2 146 ? -1.409 15.214 2.384 1.00 91.73 ? 146 HIS B N 146 HIS B N 1 ATOM 2494 C CA . HIS B 2 146 ? -1.185 16.023 1.191 1.00 91.73 ? 146 HIS B CA 146 HIS B CA 1 ATOM 2495 C C . HIS B 2 146 ? -1.202 17.511 1.523 1.00 91.73 ? 146 HIS B C 146 HIS B C 1 ATOM 2496 O O . HIS B 2 146 ? -1.921 17.942 2.427 1.00 91.73 ? 146 HIS B O 146 HIS B O 1 ATOM 2497 C CB . HIS B 2 146 ? -2.239 15.711 0.127 1.00 91.73 ? 146 HIS B CB 146 HIS B CB 1 ATOM 2498 C CG . HIS B 2 146 ? -3.574 16.324 0.406 1.00 91.73 ? 146 HIS B CG 146 HIS B CG 1 ATOM 2499 N ND1 . HIS B 2 146 ? -3.960 17.538 -0.118 1.00 91.73 ? 146 HIS B ND1 146 HIS B ND1 1 ATOM 2500 C CD2 . HIS B 2 146 ? -4.614 15.886 1.154 1.00 91.73 ? 146 HIS B CD2 146 HIS B CD2 1 ATOM 2501 C CE1 . HIS B 2 146 ? -5.183 17.822 0.298 1.00 91.73 ? 146 HIS B CE1 146 HIS B CE1 1 ATOM 2502 N NE2 . HIS B 2 146 ? -5.603 16.836 1.071 1.00 91.73 ? 146 HIS B NE2 146 HIS B NE2 1 ATOM 2503 N N . ILE B 2 147 ? -0.366 18.244 0.835 1.00 90.76 ? 147 ILE B N 147 ILE B N 1 ATOM 2504 C CA . ILE B 2 147 ? -0.334 19.702 0.868 1.00 90.76 ? 147 ILE B CA 147 ILE B CA 1 ATOM 2505 C C . ILE B 2 147 ? -0.549 20.255 -0.539 1.00 90.76 ? 147 ILE B C 147 ILE B C 1 ATOM 2506 O O . ILE B 2 147 ? 0.274 20.036 -1.431 1.00 90.76 ? 147 ILE B O 147 ILE B O 1 ATOM 2507 C CB . ILE B 2 147 ? 0.997 20.225 1.453 1.00 90.76 ? 147 ILE B CB 147 ILE B CB 1 ATOM 2508 C CG1 . ILE B 2 147 ? 1.228 19.649 2.854 1.00 90.76 ? 147 ILE B CG1 147 ILE B CG1 1 ATOM 2509 C CG2 . ILE B 2 147 ? 1.009 21.756 1.481 1.00 90.76 ? 147 ILE B CG2 147 ILE B CG2 1 ATOM 2510 C CD1 . ILE B 2 147 ? 0.220 20.122 3.892 1.00 90.76 ? 147 ILE B CD1 147 ILE B CD1 1 ATOM 2511 N N . ASP B 2 148 ? -1.630 20.831 -0.710 1.00 87.09 ? 148 ASP B N 148 ASP B N 1 ATOM 2512 C CA . ASP B 2 148 ? -1.972 21.413 -2.004 1.00 87.09 ? 148 ASP B CA 148 ASP B CA 1 ATOM 2513 C C . ASP B 2 148 ? -2.013 20.343 -3.093 1.00 87.09 ? 148 ASP B C 148 ASP B C 1 ATOM 2514 O O . ASP B 2 148 ? -1.600 20.589 -4.228 1.00 87.09 ? 148 ASP B O 148 ASP B O 1 ATOM 2515 C CB . ASP B 2 148 ? -0.972 22.508 -2.381 1.00 87.09 ? 148 ASP B CB 148 ASP B CB 1 ATOM 2516 C CG . ASP B 2 148 ? -1.483 23.425 -3.479 1.00 87.09 ? 148 ASP B CG 148 ASP B CG 1 ATOM 2517 O OD1 . ASP B 2 148 ? -2.708 23.460 -3.723 1.00 87.09 ? 148 ASP B OD1 148 ASP B OD1 1 ATOM 2518 O OD2 . ASP B 2 148 ? -0.652 24.116 -4.107 1.00 87.09 ? 148 ASP B OD2 148 ASP B OD2 1 ATOM 2519 N N . GLY B 2 149 ? -2.259 19.139 -2.731 1.00 86.01 ? 149 GLY B N 149 GLY B N 1 ATOM 2520 C CA . GLY B 2 149 ? -2.373 18.070 -3.710 1.00 86.01 ? 149 GLY B CA 149 GLY B CA 1 ATOM 2521 C C . GLY B 2 149 ? -1.109 17.240 -3.837 1.00 86.01 ? 149 GLY B C 149 GLY B C 1 ATOM 2522 O O . GLY B 2 149 ? -1.116 16.182 -4.470 1.00 86.01 ? 149 GLY B O 149 GLY B O 1 ATOM 2523 N N . TYR B 2 150 ? 0.039 17.743 -3.278 1.00 89.37 ? 150 TYR B N 150 TYR B N 1 ATOM 2524 C CA . TYR B 2 150 ? 1.282 16.981 -3.252 1.00 89.37 ? 150 TYR B CA 150 TYR B CA 1 ATOM 2525 C C . TYR B 2 150 ? 1.290 15.990 -2.094 1.00 89.37 ? 150 TYR B C 150 TYR B C 1 ATOM 2526 O O . TYR B 2 150 ? 1.336 16.389 -0.928 1.00 89.37 ? 150 TYR B O 150 TYR B O 1 ATOM 2527 C CB . TYR B 2 150 ? 2.487 17.920 -3.143 1.00 89.37 ? 150 TYR B CB 150 TYR B CB 1 ATOM 2528 C CG . TYR B 2 150 ? 2.591 18.908 -4.280 1.00 89.37 ? 150 TYR B CG 150 TYR B CG 1 ATOM 2529 C CD1 . TYR B 2 150 ? 3.151 18.538 -5.501 1.00 89.37 ? 150 TYR B CD1 150 TYR B CD1 1 ATOM 2530 C CD2 . TYR B 2 150 ? 2.130 20.212 -4.135 1.00 89.37 ? 150 TYR B CD2 150 TYR B CD2 1 ATOM 2531 C CE1 . TYR B 2 150 ? 3.250 19.446 -6.550 1.00 89.37 ? 150 TYR B CE1 150 TYR B CE1 1 ATOM 2532 C CE2 . TYR B 2 150 ? 2.225 21.128 -5.178 1.00 89.37 ? 150 TYR B CE2 150 TYR B CE2 1 ATOM 2533 C CZ . TYR B 2 150 ? 2.785 20.736 -6.380 1.00 89.37 ? 150 TYR B CZ 150 TYR B CZ 1 ATOM 2534 O OH . TYR B 2 150 ? 2.881 21.638 -7.416 1.00 89.37 ? 150 TYR B OH 150 TYR B OH 1 ATOM 2535 N N . THR B 2 151 ? 1.243 14.760 -2.477 1.00 89.95 ? 151 THR B N 151 THR B N 1 ATOM 2536 C CA . THR B 2 151 ? 0.920 13.718 -1.509 1.00 89.95 ? 151 THR B CA 151 THR B CA 1 ATOM 2537 C C . THR B 2 151 ? 2.174 12.949 -1.103 1.00 89.95 ? 151 THR B C 151 THR B C 1 ATOM 2538 O O . THR B 2 151 ? 3.080 12.755 -1.917 1.00 89.95 ? 151 THR B O 151 THR B O 1 ATOM 2539 C CB . THR B 2 151 ? -0.127 12.738 -2.070 1.00 89.95 ? 151 THR B CB 151 THR B CB 1 ATOM 2540 O OG1 . THR B 2 151 ? 0.373 12.155 -3.280 1.00 89.95 ? 151 THR B OG1 151 THR B OG1 1 ATOM 2541 C CG2 . THR B 2 151 ? -1.442 13.451 -2.368 1.00 89.95 ? 151 THR B CG2 151 THR B CG2 1 ATOM 2542 N N . SER B 2 152 ? 2.270 12.669 0.131 1.00 92.63 ? 152 SER B N 152 SER B N 1 ATOM 2543 C CA . SER B 2 152 ? 3.270 11.776 0.707 1.00 92.63 ? 152 SER B CA 152 SER B CA 1 ATOM 2544 C C . SER B 2 152 ? 2.614 10.633 1.474 1.00 92.63 ? 152 SER B C 152 SER B C 1 ATOM 2545 O O . SER B 2 152 ? 1.851 10.867 2.414 1.00 92.63 ? 152 SER B O 152 SER B O 1 ATOM 2546 C CB . SER B 2 152 ? 4.211 12.549 1.632 1.00 92.63 ? 152 SER B CB 152 SER B CB 1 ATOM 2547 O OG . SER B 2 152 ? 4.950 13.515 0.905 1.00 92.63 ? 152 SER B OG 152 SER B OG 1 ATOM 2548 N N . GLU B 2 153 ? 2.980 9.458 1.048 1.00 93.35 ? 153 GLU B N 153 GLU B N 1 ATOM 2549 C CA . GLU B 2 153 ? 2.398 8.250 1.625 1.00 93.35 ? 153 GLU B CA 153 GLU B CA 1 ATOM 2550 C C . GLU B 2 153 ? 3.473 7.355 2.233 1.00 93.35 ? 153 GLU B C 153 GLU B C 1 ATOM 2551 O O . GLU B 2 153 ? 4.568 7.228 1.681 1.00 93.35 ? 153 GLU B O 153 GLU B O 1 ATOM 2552 C CB . GLU B 2 153 ? 1.606 7.477 0.568 1.00 93.35 ? 153 GLU B CB 153 GLU B CB 1 ATOM 2553 C CG . GLU B 2 153 ? 1.048 6.151 1.064 1.00 93.35 ? 153 GLU B CG 153 GLU B CG 1 ATOM 2554 C CD . GLU B 2 153 ? 0.305 5.373 -0.009 1.00 93.35 ? 153 GLU B CD 153 GLU B CD 1 ATOM 2555 O OE1 . GLU B 2 153 ? -0.108 4.220 0.252 1.00 93.35 ? 153 GLU B OE1 153 GLU B OE1 1 ATOM 2556 O OE2 . GLU B 2 153 ? 0.134 5.920 -1.122 1.00 93.35 ? 153 GLU B OE2 153 GLU B OE2 1 ATOM 2557 N N . VAL B 2 154 ? 3.103 6.692 3.384 1.00 95.02 ? 154 VAL B N 154 VAL B N 1 ATOM 2558 C CA . VAL B 2 154 ? 4.059 5.793 4.022 1.00 95.02 ? 154 VAL B CA 154 VAL B CA 1 ATOM 2559 C C . VAL B 2 154 ? 3.336 4.550 4.535 1.00 95.02 ? 154 VAL B C 154 VAL B C 1 ATOM 2560 O O . VAL B 2 154 ? 2.199 4.635 5.006 1.00 95.02 ? 154 VAL B O 154 VAL B O 1 ATOM 2561 C CB . VAL B 2 154 ? 4.808 6.490 5.180 1.00 95.02 ? 154 VAL B CB 154 VAL B CB 1 ATOM 2562 C CG1 . VAL B 2 154 ? 3.829 6.943 6.262 1.00 95.02 ? 154 VAL B CG1 154 VAL B CG1 1 ATOM 2563 C CG2 . VAL B 2 154 ? 5.865 5.558 5.768 1.00 95.02 ? 154 VAL B CG2 154 VAL B CG2 1 ATOM 2564 N N . SER B 2 155 ? 3.918 3.421 4.316 1.00 95.55 ? 155 SER B N 155 SER B N 1 ATOM 2565 C CA . SER B 2 155 ? 3.495 2.165 4.928 1.00 95.55 ? 155 SER B CA 155 SER B CA 1 ATOM 2566 C C . SER B 2 155 ? 4.682 1.408 5.514 1.00 95.55 ? 155 SER B C 155 SER B C 1 ATOM 2567 O O . SER B 2 155 ? 5.696 1.216 4.841 1.00 95.55 ? 155 SER B O 155 SER B O 1 ATOM 2568 C CB . SER B 2 155 ? 2.774 1.286 3.905 1.00 95.55 ? 155 SER B CB 155 SER B CB 1 ATOM 2569 O OG . SER B 2 155 ? 2.296 0.098 4.511 1.00 95.55 ? 155 SER B OG 155 SER B OG 1 ATOM 2570 N N . HIS B 2 156 ? 4.529 1.090 6.769 1.00 96.39 ? 156 HIS B N 156 HIS B N 1 ATOM 2571 C CA . HIS B 2 156 ? 5.606 0.398 7.467 1.00 96.39 ? 156 HIS B CA 156 HIS B CA 1 ATOM 2572 C C . HIS B 2 156 ? 5.074 -0.795 8.255 1.00 96.39 ? 156 HIS B C 156 HIS B C 1 ATOM 2573 O O . HIS B 2 156 ? 4.076 -0.678 8.970 1.00 96.39 ? 156 HIS B O 156 HIS B O 1 ATOM 2574 C CB . HIS B 2 156 ? 6.342 1.359 8.403 1.00 96.39 ? 156 HIS B CB 156 HIS B CB 1 ATOM 2575 C CG . HIS B 2 156 ? 7.458 0.718 9.165 1.00 96.39 ? 156 HIS B CG 156 HIS B CG 1 ATOM 2576 N ND1 . HIS B 2 156 ? 8.548 0.146 8.546 1.00 96.39 ? 156 HIS B ND1 156 HIS B ND1 1 ATOM 2577 C CD2 . HIS B 2 156 ? 7.651 0.562 10.496 1.00 96.39 ? 156 HIS B CD2 156 HIS B CD2 1 ATOM 2578 C CE1 . HIS B 2 156 ? 9.366 -0.336 9.467 1.00 96.39 ? 156 HIS B CE1 156 HIS B CE1 1 ATOM 2579 N NE2 . HIS B 2 156 ? 8.845 -0.097 10.658 1.00 96.39 ? 156 HIS B NE2 156 HIS B NE2 1 ATOM 2580 N N . THR B 2 157 ? 5.823 -1.892 8.058 1.00 96.38 ? 157 THR B N 157 THR B N 1 ATOM 2581 C CA . THR B 2 157 ? 5.449 -3.111 8.767 1.00 96.38 ? 157 THR B CA 157 THR B CA 1 ATOM 2582 C C . THR B 2 157 ? 6.167 -3.197 10.111 1.00 96.38 ? 157 THR B C 157 THR B C 1 ATOM 2583 O O . THR B 2 157 ? 7.390 -3.056 10.178 1.00 96.38 ? 157 THR B O 157 THR B O 1 ATOM 2584 C CB . THR B 2 157 ? 5.767 -4.364 7.931 1.00 96.38 ? 157 THR B CB 157 THR B CB 1 ATOM 2585 O OG1 . THR B 2 157 ? 5.028 -4.313 6.704 1.00 96.38 ? 157 THR B OG1 157 THR B OG1 1 ATOM 2586 C CG2 . THR B 2 157 ? 5.394 -5.637 8.683 1.00 96.38 ? 157 THR B CG2 157 THR B CG2 1 ATOM 2587 N N . MET B 2 158 ? 5.375 -3.378 11.217 1.00 94.83 ? 158 MET B N 158 MET B N 1 ATOM 2588 C CA . MET B 2 158 ? 5.873 -3.521 12.582 1.00 94.83 ? 158 MET B CA 158 MET B CA 1 ATOM 2589 C C . MET B 2 158 ? 5.476 -4.872 13.168 1.00 94.83 ? 158 MET B C 158 MET B C 1 ATOM 2590 O O . MET B 2 158 ? 4.396 -5.387 12.873 1.00 94.83 ? 158 MET B O 158 MET B O 1 ATOM 2591 C CB . MET B 2 158 ? 5.347 -2.391 13.468 1.00 94.83 ? 158 MET B CB 158 MET B CB 1 ATOM 2592 C CG . MET B 2 158 ? 5.887 -2.424 14.889 1.00 94.83 ? 158 MET B CG 158 MET B CG 1 ATOM 2593 S SD . MET B 2 158 ? 5.246 -1.047 15.917 1.00 94.83 ? 158 MET B SD 158 MET B SD 1 ATOM 2594 C CE . MET B 2 158 ? 5.365 -1.796 17.566 1.00 94.83 ? 158 MET B CE 158 MET B CE 1 ATOM 2595 N N . VAL B 2 159 ? 6.359 -5.415 14.050 1.00 95.16 ? 159 VAL B N 159 VAL B N 1 ATOM 2596 C CA . VAL B 2 159 ? 6.094 -6.708 14.673 1.00 95.16 ? 159 VAL B CA 159 VAL B CA 1 ATOM 2597 C C . VAL B 2 159 ? 5.736 -6.508 16.144 1.00 95.16 ? 159 VAL B C 159 VAL B C 1 ATOM 2598 O O . VAL B 2 159 ? 6.388 -5.734 16.849 1.00 95.16 ? 159 VAL B O 159 VAL B O 1 ATOM 2599 C CB . VAL B 2 159 ? 7.305 -7.659 14.544 1.00 95.16 ? 159 VAL B CB 159 VAL B CB 1 ATOM 2600 C CG1 . VAL B 2 159 ? 7.022 -8.990 15.238 1.00 95.16 ? 159 VAL B CG1 159 VAL B CG1 1 ATOM 2601 C CG2 . VAL B 2 159 ? 7.653 -7.882 13.074 1.00 95.16 ? 159 VAL B CG2 159 VAL B CG2 1 ATOM 2602 N N . ILE B 2 160 ? 4.717 -7.225 16.575 1.00 94.76 ? 160 ILE B N 160 ILE B N 1 ATOM 2603 C CA . ILE B 2 160 ? 4.360 -7.230 17.990 1.00 94.76 ? 160 ILE B CA 160 ILE B CA 1 ATOM 2604 C C . ILE B 2 160 ? 5.089 -8.367 18.702 1.00 94.76 ? 160 ILE B C 160 ILE B C 1 ATOM 2605 O O . ILE B 2 160 ? 4.865 -9.541 18.401 1.00 94.76 ? 160 ILE B O 160 ILE B O 1 ATOM 2606 C CB . ILE B 2 160 ? 2.833 -7.366 18.187 1.00 94.76 ? 160 ILE B CB 160 ILE B CB 1 ATOM 2607 C CG1 . ILE B 2 160 ? 2.096 -6.251 17.436 1.00 94.76 ? 160 ILE B CG1 160 ILE B CG1 1 ATOM 2608 C CG2 . ILE B 2 160 ? 2.477 -7.352 19.676 1.00 94.76 ? 160 ILE B CG2 160 ILE B CG2 1 ATOM 2609 C CD1 . ILE B 2 160 ? 2.470 -4.847 17.891 1.00 94.76 ? 160 ILE B CD1 160 ILE B CD1 1 ATOM 2610 N N . TYR B 2 161 ? 5.931 -7.974 19.679 1.00 92.93 ? 161 TYR B N 161 TYR B N 1 ATOM 2611 C CA . TYR B 2 161 ? 6.754 -8.949 20.384 1.00 92.93 ? 161 TYR B CA 161 TYR B CA 1 ATOM 2612 C C . TYR B 2 161 ? 6.159 -9.282 21.746 1.00 92.93 ? 161 TYR B C 161 TYR B C 1 ATOM 2613 O O . TYR B 2 161 ? 5.498 -8.444 22.364 1.00 92.93 ? 161 TYR B O 161 TYR B O 1 ATOM 2614 C CB . TYR B 2 161 ? 8.183 -8.425 20.553 1.00 92.93 ? 161 TYR B CB 161 TYR B CB 1 ATOM 2615 C CG . TYR B 2 161 ? 8.930 -8.266 19.250 1.00 92.93 ? 161 TYR B CG 161 TYR B CG 1 ATOM 2616 C CD1 . TYR B 2 161 ? 9.448 -9.374 18.583 1.00 92.93 ? 161 TYR B CD1 161 TYR B CD1 1 ATOM 2617 C CD2 . TYR B 2 161 ? 9.119 -7.010 18.686 1.00 92.93 ? 161 TYR B CD2 161 TYR B CD2 1 ATOM 2618 C CE1 . TYR B 2 161 ? 10.138 -9.232 17.383 1.00 92.93 ? 161 TYR B CE1 161 TYR B CE1 1 ATOM 2619 C CE2 . TYR B 2 161 ? 9.808 -6.856 17.487 1.00 92.93 ? 161 TYR B CE2 161 TYR B CE2 1 ATOM 2620 C CZ . TYR B 2 161 ? 10.312 -7.972 16.844 1.00 92.93 ? 161 TYR B CZ 161 TYR B CZ 1 ATOM 2621 O OH . TYR B 2 161 ? 10.995 -7.826 15.657 1.00 92.93 ? 161 TYR B OH 161 TYR B OH 1 ATOM 2622 N N . PRO B 2 162 ? 6.395 -10.491 22.106 1.00 89.12 ? 162 PRO B N 162 PRO B N 1 ATOM 2623 C CA . PRO B 2 162 ? 6.040 -10.794 23.494 1.00 89.12 ? 162 PRO B CA 162 PRO B CA 1 ATOM 2624 C C . PRO B 2 162 ? 6.938 -10.080 24.502 1.00 89.12 ? 162 PRO B C 162 PRO B C 1 ATOM 2625 O O . PRO B 2 162 ? 8.111 -9.826 24.218 1.00 89.12 ? 162 PRO B O 162 PRO B O 1 ATOM 2626 C CB . PRO B 2 162 ? 6.221 -12.312 23.581 1.00 89.12 ? 162 PRO B CB 162 PRO B CB 1 ATOM 2627 C CG . PRO B 2 162 ? 7.238 -12.636 22.534 1.00 89.12 ? 162 PRO B CG 162 PRO B CG 1 ATOM 2628 C CD . PRO B 2 162 ? 7.125 -11.623 21.431 1.00 89.12 ? 162 PRO B CD 162 PRO B CD 1 ATOM 2629 N N . VAL B 2 163 ? 6.314 -9.611 25.573 1.00 83.28 ? 163 VAL B N 163 VAL B N 1 ATOM 2630 C CA . VAL B 2 163 ? 7.052 -8.871 26.592 1.00 83.28 ? 163 VAL B CA 163 VAL B CA 1 ATOM 2631 C C . VAL B 2 163 ? 7.337 -9.778 27.786 1.00 83.28 ? 163 VAL B C 163 VAL B C 1 ATOM 2632 O O . VAL B 2 163 ? 6.437 -10.459 28.285 1.00 83.28 ? 163 VAL B O 163 VAL B O 1 ATOM 2633 C CB . VAL B 2 163 ? 6.281 -7.613 27.050 1.00 83.28 ? 163 VAL B CB 163 VAL B CB 1 ATOM 2634 C CG1 . VAL B 2 163 ? 7.080 -6.841 28.098 1.00 83.28 ? 163 VAL B CG1 163 VAL B CG1 1 ATOM 2635 C CG2 . VAL B 2 163 ? 5.961 -6.719 25.853 1.00 83.28 ? 163 VAL B CG2 163 VAL B CG2 1 ATOM 2636 N N . ASP B 2 164 ? 8.671 -9.925 28.056 1.00 80.32 ? 164 ASP B N 164 ASP B N 1 ATOM 2637 C CA . ASP B 2 164 ? 9.065 -10.637 29.268 1.00 80.32 ? 164 ASP B CA 164 ASP B CA 1 ATOM 2638 C C . ASP B 2 164 ? 8.855 -9.770 30.508 1.00 80.32 ? 164 ASP B C 164 ASP B C 1 ATOM 2639 O O . ASP B 2 164 ? 9.510 -8.738 30.667 1.00 80.32 ? 164 ASP B O 164 ASP B O 1 ATOM 2640 C CB . ASP B 2 164 ? 10.526 -11.082 29.179 1.00 80.32 ? 164 ASP B CB 164 ASP B CB 1 ATOM 2641 C CG . ASP B 2 164 ? 10.885 -12.147 30.200 1.00 80.32 ? 164 ASP B CG 164 ASP B CG 1 ATOM 2642 O OD1 . ASP B 2 164 ? 10.062 -12.436 31.095 1.00 80.32 ? 164 ASP B OD1 164 ASP B OD1 1 ATOM 2643 O OD2 . ASP B 2 164 ? 12.003 -12.700 30.110 1.00 80.32 ? 164 ASP B OD2 164 ASP B OD2 1 ATOM 2644 N N . GLU B 2 165 ? 7.868 -10.082 31.313 1.00 76.92 ? 165 GLU B N 165 GLU B N 1 ATOM 2645 C CA . GLU B 2 165 ? 7.553 -9.299 32.504 1.00 76.92 ? 165 GLU B CA 165 GLU B CA 1 ATOM 2646 C C . GLU B 2 165 ? 8.637 -9.450 33.567 1.00 76.92 ? 165 GLU B C 165 GLU B C 1 ATOM 2647 O O . GLU B 2 165 ? 8.669 -8.695 34.540 1.00 76.92 ? 165 GLU B O 165 GLU B O 1 ATOM 2648 C CB . GLU B 2 165 ? 6.194 -9.713 33.075 1.00 76.92 ? 165 GLU B CB 165 GLU B CB 1 ATOM 2649 C CG . GLU B 2 165 ? 5.016 -9.358 32.179 1.00 76.92 ? 165 GLU B CG 165 GLU B CG 1 ATOM 2650 C CD . GLU B 2 165 ? 3.674 -9.765 32.765 1.00 76.92 ? 165 GLU B CD 165 GLU B CD 1 ATOM 2651 O OE1 . GLU B 2 165 ? 2.630 -9.522 32.117 1.00 76.92 ? 165 GLU B OE1 165 GLU B OE1 1 ATOM 2652 O OE2 . GLU B 2 165 ? 3.665 -10.332 33.880 1.00 76.92 ? 165 GLU B OE2 165 GLU B OE2 1 ATOM 2653 N N . THR B 2 166 ? 9.599 -10.309 33.441 1.00 78.41 ? 166 THR B N 166 THR B N 1 ATOM 2654 C CA . THR B 2 166 ? 10.613 -10.579 34.453 1.00 78.41 ? 166 THR B CA 166 THR B CA 1 ATOM 2655 C C . THR B 2 166 ? 11.735 -9.546 34.384 1.00 78.41 ? 166 THR B C 166 THR B C 1 ATOM 2656 O O . THR B 2 166 ? 12.381 -9.255 35.393 1.00 78.41 ? 166 THR B O 166 THR B O 1 ATOM 2657 C CB . THR B 2 166 ? 11.203 -11.992 34.290 1.00 78.41 ? 166 THR B CB 166 THR B CB 1 ATOM 2658 O OG1 . THR B 2 166 ? 11.753 -12.125 32.974 1.00 78.41 ? 166 THR B OG1 166 THR B OG1 1 ATOM 2659 C CG2 . THR B 2 166 ? 10.133 -13.061 34.492 1.00 78.41 ? 166 THR B CG2 166 THR B CG2 1 ATOM 2660 N N . LYS B 2 167 ? 11.923 -8.846 33.287 1.00 75.15 ? 167 LYS B N 167 LYS B N 1 ATOM 2661 C CA . LYS B 2 167 ? 12.976 -7.847 33.129 1.00 75.15 ? 167 LYS B CA 167 LYS B CA 1 ATOM 2662 C C . LYS B 2 167 ? 12.473 -6.455 33.499 1.00 75.15 ? 167 LYS B C 167 LYS B C 1 ATOM 2663 O O . LYS B 2 167 ? 11.293 -6.147 33.318 1.00 75.15 ? 167 LYS B O 167 LYS B O 1 ATOM 2664 C CB . LYS B 2 167 ? 13.507 -7.849 31.695 1.00 75.15 ? 167 LYS B CB 167 LYS B CB 1 ATOM 2665 C CG . LYS B 2 167 ? 14.295 -9.098 31.328 1.00 75.15 ? 167 LYS B CG 167 LYS B CG 1 ATOM 2666 C CD . LYS B 2 167 ? 14.898 -8.988 29.934 1.00 75.15 ? 167 LYS B CD 167 LYS B CD 1 ATOM 2667 C CE . LYS B 2 167 ? 15.653 -10.254 29.549 1.00 75.15 ? 167 LYS B CE 167 LYS B CE 1 ATOM 2668 N NZ . LYS B 2 167 ? 16.230 -10.159 28.175 1.00 75.15 ? 167 LYS B NZ 167 LYS B NZ 1 ATOM 2669 N N . PRO B 2 168 ? 13.340 -5.690 34.221 1.00 76.11 ? 168 PRO B N 168 PRO B N 1 ATOM 2670 C CA . PRO B 2 168 ? 12.965 -4.337 34.636 1.00 76.11 ? 168 PRO B CA 168 PRO B CA 1 ATOM 2671 C C . PRO B 2 168 ? 12.615 -3.433 33.456 1.00 76.11 ? 168 PRO B C 168 PRO B C 1 ATOM 2672 O O . PRO B 2 168 ? 11.682 -2.630 33.543 1.00 76.11 ? 168 PRO B O 168 PRO B O 1 ATOM 2673 C CB . PRO B 2 168 ? 14.215 -3.830 35.360 1.00 76.11 ? 168 PRO B CB 168 PRO B CB 1 ATOM 2674 C CG . PRO B 2 168 ? 15.310 -4.746 34.917 1.00 76.11 ? 168 PRO B CG 168 PRO B CG 1 ATOM 2675 C CD . PRO B 2 168 ? 14.694 -6.029 34.436 1.00 76.11 ? 168 PRO B CD 168 PRO B CD 1 ATOM 2676 N N . ILE B 2 169 ? 13.320 -3.679 32.316 1.00 80.56 ? 169 ILE B N 169 ILE B N 1 ATOM 2677 C CA . ILE B 2 169 ? 13.075 -2.899 31.108 1.00 80.56 ? 169 ILE B CA 169 ILE B CA 1 ATOM 2678 C C . ILE B 2 169 ? 12.532 -3.808 30.008 1.00 80.56 ? 169 ILE B C 169 ILE B C 1 ATOM 2679 O O . ILE B 2 169 ? 13.185 -4.778 29.617 1.00 80.56 ? 169 ILE B O 169 ILE B O 1 ATOM 2680 C CB . ILE B 2 169 ? 14.358 -2.183 30.627 1.00 80.56 ? 169 ILE B CB 169 ILE B CB 1 ATOM 2681 C CG1 . ILE B 2 169 ? 14.914 -1.283 31.736 1.00 80.56 ? 169 ILE B CG1 169 ILE B CG1 1 ATOM 2682 C CG2 . ILE B 2 169 ? 14.082 -1.378 29.354 1.00 80.56 ? 169 ILE B CG2 169 ILE B CG2 1 ATOM 2683 C CD1 . ILE B 2 169 ? 16.343 -0.815 31.494 1.00 80.56 ? 169 ILE B CD1 169 ILE B CD1 1 ATOM 2684 N N . PRO B 2 170 ? 11.237 -3.583 29.701 1.00 80.89 ? 170 PRO B N 170 PRO B N 1 ATOM 2685 C CA . PRO B 2 170 ? 10.638 -4.461 28.693 1.00 80.89 ? 170 PRO B CA 170 PRO B CA 1 ATOM 2686 C C . PRO B 2 170 ? 11.453 -4.520 27.403 1.00 80.89 ? 170 PRO B C 170 PRO B C 1 ATOM 2687 O O . PRO B 2 170 ? 11.813 -3.479 26.848 1.00 80.89 ? 170 PRO B O 170 PRO B O 1 ATOM 2688 C CB . PRO B 2 170 ? 9.267 -3.828 28.444 1.00 80.89 ? 170 PRO B CB 170 PRO B CB 1 ATOM 2689 C CG . PRO B 2 170 ? 9.410 -2.413 28.903 1.00 80.89 ? 170 PRO B CG 170 PRO B CG 1 ATOM 2690 C CD . PRO B 2 170 ? 10.535 -2.346 29.896 1.00 80.89 ? 170 PRO B CD 170 PRO B CD 1 ATOM 2691 N N . GLN B 2 171 ? 11.981 -5.665 27.103 1.00 83.80 ? 171 GLN B N 171 GLN B N 1 ATOM 2692 C CA . GLN B 2 171 ? 12.683 -5.930 25.852 1.00 83.80 ? 171 GLN B CA 171 GLN B CA 1 ATOM 2693 C C . GLN B 2 171 ? 11.987 -7.028 25.052 1.00 83.80 ? 171 GLN B C 171 GLN B C 1 ATOM 2694 O O . GLN B 2 171 ? 11.319 -7.891 25.625 1.00 83.80 ? 171 GLN B O 171 GLN B O 1 ATOM 2695 C CB . GLN B 2 171 ? 14.137 -6.320 26.124 1.00 83.80 ? 171 GLN B CB 171 GLN B CB 1 ATOM 2696 C CG . GLN B 2 171 ? 15.000 -5.168 26.620 1.00 83.80 ? 171 GLN B CG 171 GLN B CG 1 ATOM 2697 C CD . GLN B 2 171 ? 16.454 -5.562 26.807 1.00 83.80 ? 171 GLN B CD 171 GLN B CD 1 ATOM 2698 O OE1 . GLN B 2 171 ? 16.835 -6.712 26.567 1.00 83.80 ? 171 GLN B OE1 171 GLN B OE1 1 ATOM 2699 N NE2 . GLN B 2 171 ? 17.275 -4.610 27.236 1.00 83.80 ? 171 GLN B NE2 171 GLN B NE2 1 ATOM 2700 N N . PRO B 2 172 ? 12.066 -6.936 23.741 1.00 84.43 ? 172 PRO B N 172 PRO B N 1 ATOM 2701 C CA . PRO B 2 172 ? 11.447 -7.990 22.933 1.00 84.43 ? 172 PRO B CA 172 PRO B CA 1 ATOM 2702 C C . PRO B 2 172 ? 12.095 -9.356 23.149 1.00 84.43 ? 172 PRO B C 172 PRO B C 1 ATOM 2703 O O . PRO B 2 172 ? 13.309 -9.442 23.354 1.00 84.43 ? 172 PRO B O 172 PRO B O 1 ATOM 2704 C CB . PRO B 2 172 ? 11.661 -7.505 21.497 1.00 84.43 ? 172 PRO B CB 172 PRO B CB 1 ATOM 2705 C CG . PRO B 2 172 ? 12.831 -6.579 21.577 1.00 84.43 ? 172 PRO B CG 172 PRO B CG 1 ATOM 2706 C CD . PRO B 2 172 ? 12.896 -6.011 22.965 1.00 84.43 ? 172 PRO B CD 172 PRO B CD 1 ATOM 2707 N N . THR B 2 173 ? 11.293 -10.445 23.326 1.00 84.05 ? 173 THR B N 173 THR B N 1 ATOM 2708 C CA . THR B 2 173 ? 11.730 -11.832 23.437 1.00 84.05 ? 173 THR B CA 173 THR B CA 1 ATOM 2709 C C . THR B 2 173 ? 12.002 -12.425 22.057 1.00 84.05 ? 173 THR B C 173 THR B C 1 ATOM 2710 O O . THR B 2 173 ? 11.125 -12.423 21.191 1.00 84.05 ? 173 THR B O 173 THR B O 1 ATOM 2711 C CB . THR B 2 173 ? 10.683 -12.691 24.170 1.00 84.05 ? 173 THR B CB 173 THR B CB 1 ATOM 2712 O OG1 . THR B 2 173 ? 9.497 -11.914 24.377 1.00 84.05 ? 173 THR B OG1 173 THR B OG1 1 ATOM 2713 C CG2 . THR B 2 173 ? 11.209 -13.164 25.522 1.00 84.05 ? 173 THR B CG2 173 THR B CG2 1 ATOM 2714 N N . GLY B 2 174 ? 13.253 -12.196 21.474 1.00 76.03 ? 174 GLY B N 174 GLY B N 1 ATOM 2715 C CA . GLY B 2 174 ? 13.854 -12.757 20.274 1.00 76.03 ? 174 GLY B CA 174 GLY B CA 1 ATOM 2716 C C . GLY B 2 174 ? 13.365 -12.097 18.998 1.00 76.03 ? 174 GLY B C 174 GLY B C 1 ATOM 2717 O O . GLY B 2 174 ? 12.501 -11.219 19.039 1.00 76.03 ? 174 GLY B O 174 GLY B O 1 ATOM 2718 N N . PRO B 2 175 ? 14.125 -12.458 18.028 1.00 90.52 ? 175 PRO B N 175 PRO B N 1 ATOM 2719 C CA . PRO B 2 175 ? 13.608 -11.967 16.749 1.00 90.52 ? 175 PRO B CA 175 PRO B CA 1 ATOM 2720 C C . PRO B 2 175 ? 12.434 -12.795 16.230 1.00 90.52 ? 175 PRO B C 175 PRO B C 1 ATOM 2721 O O . PRO B 2 175 ? 12.242 -13.936 16.657 1.00 90.52 ? 175 PRO B O 175 PRO B O 1 ATOM 2722 C CB . PRO B 2 175 ? 14.814 -12.083 15.813 1.00 90.52 ? 175 PRO B CB 175 PRO B CB 1 ATOM 2723 C CG . PRO B 2 175 ? 15.616 -13.218 16.363 1.00 90.52 ? 175 PRO B CG 175 PRO B CG 1 ATOM 2724 C CD . PRO B 2 175 ? 15.463 -13.230 17.857 1.00 90.52 ? 175 PRO B CD 175 PRO B CD 1 ATOM 2725 N N . LEU B 2 176 ? 11.617 -12.209 15.439 1.00 93.37 ? 176 LEU B N 176 LEU B N 1 ATOM 2726 C CA . LEU B 2 176 ? 10.562 -12.935 14.741 1.00 93.37 ? 176 LEU B CA 176 LEU B CA 1 ATOM 2727 C C . LEU B 2 176 ? 11.152 -13.997 13.819 1.00 93.37 ? 176 LEU B C 176 LEU B C 1 ATOM 2728 O O . LEU B 2 176 ? 12.083 -13.719 13.060 1.00 93.37 ? 176 LEU B O 176 LEU B O 1 ATOM 2729 C CB . LEU B 2 176 ? 9.690 -11.969 13.934 1.00 93.37 ? 176 LEU B CB 176 LEU B CB 1 ATOM 2730 C CG . LEU B 2 176 ? 8.502 -12.586 13.194 1.00 93.37 ? 176 LEU B CG 176 LEU B CG 1 ATOM 2731 C CD1 . LEU B 2 176 ? 7.421 -13.007 14.183 1.00 93.37 ? 176 LEU B CD1 176 LEU B CD1 1 ATOM 2732 C CD2 . LEU B 2 176 ? 7.944 -11.605 12.168 1.00 93.37 ? 176 LEU B CD2 176 LEU B CD2 1 ATOM 2733 N N . LEU B 2 177 ? 10.694 -15.175 13.956 1.00 93.17 ? 177 LEU B N 177 LEU B N 1 ATOM 2734 C CA . LEU B 2 177 ? 11.169 -16.284 13.137 1.00 93.17 ? 177 LEU B CA 177 LEU B CA 1 ATOM 2735 C C . LEU B 2 177 ? 10.056 -16.811 12.237 1.00 93.17 ? 177 LEU B C 177 LEU B C 1 ATOM 2736 O O . LEU B 2 177 ? 8.885 -16.480 12.433 1.00 93.17 ? 177 LEU B O 177 LEU B O 1 ATOM 2737 C CB . LEU B 2 177 ? 11.704 -17.414 14.021 1.00 93.17 ? 177 LEU B CB 177 LEU B CB 1 ATOM 2738 C CG . LEU B 2 177 ? 12.827 -17.042 14.991 1.00 93.17 ? 177 LEU B CG 177 LEU B CG 1 ATOM 2739 C CD1 . LEU B 2 177 ? 13.045 -18.161 16.004 1.00 93.17 ? 177 LEU B CD1 177 LEU B CD1 1 ATOM 2740 C CD2 . LEU B 2 177 ? 14.114 -16.744 14.230 1.00 93.17 ? 177 LEU B CD2 177 LEU B CD2 1 ATOM 2741 N N . GLY B 2 178 ? 10.398 -17.563 11.152 1.00 91.60 ? 178 GLY B N 178 GLY B N 1 ATOM 2742 C CA . GLY B 2 178 ? 9.419 -18.243 10.319 1.00 91.60 ? 178 GLY B CA 178 GLY B CA 1 ATOM 2743 C C . GLY B 2 178 ? 9.100 -17.493 9.040 1.00 91.60 ? 178 GLY B C 178 GLY B C 1 ATOM 2744 O O . GLY B 2 178 ? 9.889 -16.659 8.590 1.00 91.60 ? 178 GLY B O 178 GLY B O 1 ATOM 2745 N N . GLY B 2 179 ? 7.949 -17.895 8.397 1.00 92.49 ? 179 GLY B N 179 GLY B N 1 ATOM 2746 C CA . GLY B 2 179 ? 7.530 -17.344 7.118 1.00 92.49 ? 179 GLY B CA 179 GLY B CA 1 ATOM 2747 C C . GLY B 2 179 ? 7.268 -15.851 7.169 1.00 92.49 ? 179 GLY B C 179 GLY B C 1 ATOM 2748 O O . GLY B 2 179 ? 7.590 -15.126 6.225 1.00 92.49 ? 179 GLY B O 179 GLY B O 1 ATOM 2749 N N . LYS B 2 180 ? 6.791 -15.355 8.300 1.00 95.66 ? 180 LYS B N 180 LYS B N 1 ATOM 2750 C CA . LYS B 2 180 ? 6.523 -13.927 8.449 1.00 95.66 ? 180 LYS B CA 180 LYS B CA 1 ATOM 2751 C C . LYS B 2 180 ? 7.819 -13.121 8.439 1.00 95.66 ? 180 LYS B C 180 LYS B C 1 ATOM 2752 O O . LYS B 2 180 ? 7.867 -12.019 7.890 1.00 95.66 ? 180 LYS B O 180 LYS B O 1 ATOM 2753 C CB . LYS B 2 180 ? 5.748 -13.658 9.739 1.00 95.66 ? 180 LYS B CB 180 LYS B CB 1 ATOM 2754 C CG . LYS B 2 180 ? 4.319 -14.179 9.723 1.00 95.66 ? 180 LYS B CG 180 LYS B CG 1 ATOM 2755 C CD . LYS B 2 180 ? 3.575 -13.812 11.001 1.00 95.66 ? 180 LYS B CD 180 LYS B CD 1 ATOM 2756 C CE . LYS B 2 180 ? 2.142 -14.326 10.982 1.00 95.66 ? 180 LYS B CE 180 LYS B CE 1 ATOM 2757 N NZ . LYS B 2 180 ? 1.415 -13.986 12.242 1.00 95.66 ? 180 LYS B NZ 180 LYS B NZ 1 ATOM 2758 N N . ALA B 2 181 ? 8.862 -13.716 9.042 1.00 95.65 ? 181 ALA B N 181 ALA B N 1 ATOM 2759 C CA . ALA B 2 181 ? 10.169 -13.066 9.059 1.00 95.65 ? 181 ALA B CA 181 ALA B CA 1 ATOM 2760 C C . ALA B 2 181 ? 10.747 -12.959 7.650 1.00 95.65 ? 181 ALA B C 181 ALA B C 1 ATOM 2761 O O . ALA B 2 181 ? 11.359 -11.947 7.299 1.00 95.65 ? 181 ALA B O 181 ALA B O 1 ATOM 2762 C CB . ALA B 2 181 ? 11.131 -13.828 9.968 1.00 95.65 ? 181 ALA B CB 181 ALA B CB 1 ATOM 2763 N N . ASP B 2 182 ? 10.477 -13.998 6.830 1.00 95.39 ? 182 ASP B N 182 ASP B N 1 ATOM 2764 C CA . ASP B 2 182 ? 10.942 -13.999 5.446 1.00 95.39 ? 182 ASP B CA 182 ASP B CA 1 ATOM 2765 C C . ASP B 2 182 ? 10.302 -12.862 4.651 1.00 95.39 ? 182 ASP B C 182 ASP B C 1 ATOM 2766 O O . ASP B 2 182 ? 10.977 -12.186 3.872 1.00 95.39 ? 182 ASP B O 182 ASP B O 1 ATOM 2767 C CB . ASP B 2 182 ? 10.640 -15.342 4.779 1.00 95.39 ? 182 ASP B CB 182 ASP B CB 1 ATOM 2768 C CG . ASP B 2 182 ? 11.362 -16.506 5.435 1.00 95.39 ? 182 ASP B CG 182 ASP B CG 1 ATOM 2769 O OD1 . ASP B 2 182 ? 12.432 -16.293 6.046 1.00 95.39 ? 182 ASP B OD1 182 ASP B OD1 1 ATOM 2770 O OD2 . ASP B 2 182 ? 10.858 -17.646 5.338 1.00 95.39 ? 182 ASP B OD2 182 ASP B OD2 1 ATOM 2771 N N . ALA B 2 183 ? 9.010 -12.668 4.837 1.00 96.55 ? 183 ALA B N 183 ALA B N 1 ATOM 2772 C CA . ALA B 2 183 ? 8.270 -11.632 4.122 1.00 96.55 ? 183 ALA B CA 183 ALA B CA 1 ATOM 2773 C C . ALA B 2 183 ? 8.764 -10.240 4.507 1.00 96.55 ? 183 ALA B C 183 ALA B C 1 ATOM 2774 O O . ALA B 2 183 ? 8.952 -9.380 3.644 1.00 96.55 ? 183 ALA B O 183 ALA B O 1 ATOM 2775 C CB . ALA B 2 183 ? 6.774 -11.758 4.400 1.00 96.55 ? 183 ALA B CB 183 ALA B CB 1 ATOM 2776 N N . VAL B 2 184 ? 9.050 -10.046 5.826 1.00 96.76 ? 184 VAL B N 184 VAL B N 1 ATOM 2777 C CA . VAL B 2 184 ? 9.508 -8.753 6.324 1.00 96.76 ? 184 VAL B CA 184 VAL B CA 1 ATOM 2778 C C . VAL B 2 184 ? 10.903 -8.454 5.778 1.00 96.76 ? 184 VAL B C 184 VAL B C 1 ATOM 2779 O O . VAL B 2 184 ? 11.172 -7.339 5.323 1.00 96.76 ? 184 VAL B O 184 VAL B O 1 ATOM 2780 C CB . VAL B 2 184 ? 9.520 -8.712 7.868 1.00 96.76 ? 184 VAL B CB 184 VAL B CB 1 ATOM 2781 C CG1 . VAL B 2 184 ? 10.161 -7.419 8.369 1.00 96.76 ? 184 VAL B CG1 184 VAL B CG1 1 ATOM 2782 C CG2 . VAL B 2 184 ? 8.101 -8.855 8.416 1.00 96.76 ? 184 VAL B CG2 184 VAL B CG2 1 ATOM 2783 N N . ALA B 2 185 ? 11.736 -9.456 5.795 1.00 95.95 ? 185 ALA B N 185 ALA B N 1 ATOM 2784 C CA . ALA B 2 185 ? 13.097 -9.293 5.292 1.00 95.95 ? 185 ALA B CA 185 ALA B CA 1 ATOM 2785 C C . ALA B 2 185 ? 13.095 -8.950 3.805 1.00 95.95 ? 185 ALA B C 185 ALA B C 1 ATOM 2786 O O . ALA B 2 185 ? 13.766 -8.008 3.378 1.00 95.95 ? 185 ALA B O 185 ALA B O 1 ATOM 2787 C CB . ALA B 2 185 ? 13.912 -10.560 5.541 1.00 95.95 ? 185 ALA B CB 185 ALA B CB 1 ATOM 2788 N N . ALA B 2 186 ? 12.317 -9.691 3.075 1.00 96.63 ? 186 ALA B N 186 ALA B N 1 ATOM 2789 C CA . ALA B 2 186 ? 12.244 -9.494 1.629 1.00 96.63 ? 186 ALA B CA 186 ALA B CA 1 ATOM 2790 C C . ALA B 2 186 ? 11.698 -8.110 1.291 1.00 96.63 ? 186 ALA B C 186 ALA B C 1 ATOM 2791 O O . ALA B 2 186 ? 12.240 -7.416 0.427 1.00 96.63 ? 186 ALA B O 186 ALA B O 1 ATOM 2792 C CB . ALA B 2 186 ? 11.379 -10.576 0.987 1.00 96.63 ? 186 ALA B CB 186 ALA B CB 1 ATOM 2793 N N . ALA B 2 187 ? 10.620 -7.714 1.959 1.00 96.81 ? 187 ALA B N 187 ALA B N 1 ATOM 2794 C CA . ALA B 2 187 ? 9.988 -6.424 1.700 1.00 96.81 ? 187 ALA B CA 187 ALA B CA 1 ATOM 2795 C C . ALA B 2 187 ? 10.945 -5.274 1.998 1.00 96.81 ? 187 ALA B C 187 ALA B C 1 ATOM 2796 O O . ALA B 2 187 ? 11.066 -4.337 1.205 1.00 96.81 ? 187 ALA B O 187 ALA B O 1 ATOM 2797 C CB . ALA B 2 187 ? 8.714 -6.280 2.529 1.00 96.81 ? 187 ALA B CB 187 ALA B CB 1 ATOM 2798 N N . HIS B 2 188 ? 11.656 -5.362 3.112 1.00 95.80 ? 188 HIS B N 188 HIS B N 1 ATOM 2799 C CA . HIS B 2 188 ? 12.570 -4.307 3.533 1.00 95.80 ? 188 HIS B CA 188 HIS B CA 1 ATOM 2800 C C . HIS B 2 188 ? 13.764 -4.202 2.589 1.00 95.80 ? 188 HIS B C 188 HIS B C 1 ATOM 2801 O O . HIS B 2 188 ? 14.132 -3.104 2.166 1.00 95.80 ? 188 HIS B O 188 HIS B O 1 ATOM 2802 C CB . HIS B 2 188 ? 13.053 -4.555 4.963 1.00 95.80 ? 188 HIS B CB 188 HIS B CB 1 ATOM 2803 C CG . HIS B 2 188 ? 13.983 -3.501 5.474 1.00 95.80 ? 188 HIS B CG 188 HIS B CG 1 ATOM 2804 N ND1 . HIS B 2 188 ? 15.353 -3.603 5.365 1.00 95.80 ? 188 HIS B ND1 188 HIS B ND1 1 ATOM 2805 C CD2 . HIS B 2 188 ? 13.738 -2.323 6.094 1.00 95.80 ? 188 HIS B CD2 188 HIS B CD2 1 ATOM 2806 C CE1 . HIS B 2 188 ? 15.912 -2.530 5.899 1.00 95.80 ? 188 HIS B CE1 188 HIS B CE1 1 ATOM 2807 N NE2 . HIS B 2 188 ? 14.954 -1.737 6.349 1.00 95.80 ? 188 HIS B NE2 188 HIS B NE2 1 ATOM 2808 N N . ILE B 2 189 ? 14.407 -5.332 2.276 1.00 96.16 ? 189 ILE B N 189 ILE B N 1 ATOM 2809 C CA . ILE B 2 189 ? 15.584 -5.357 1.414 1.00 96.16 ? 189 ILE B CA 189 ILE B CA 1 ATOM 2810 C C . ILE B 2 189 ? 15.210 -4.866 0.017 1.00 96.16 ? 189 ILE B C 189 ILE B C 1 ATOM 2811 O O . ILE B 2 189 ? 15.949 -4.089 -0.593 1.00 96.16 ? 189 ILE B O 189 ILE B O 1 ATOM 2812 C CB . ILE B 2 189 ? 16.199 -6.772 1.338 1.00 96.16 ? 189 ILE B CB 189 ILE B CB 1 ATOM 2813 C CG1 . ILE B 2 189 ? 16.738 -7.194 2.709 1.00 96.16 ? 189 ILE B CG1 189 ILE B CG1 1 ATOM 2814 C CG2 . ILE B 2 189 ? 17.301 -6.826 0.276 1.00 96.16 ? 189 ILE B CG2 189 ILE B CG2 1 ATOM 2815 C CD1 . ILE B 2 189 ? 17.190 -8.647 2.776 1.00 96.16 ? 189 ILE B CD1 189 ILE B CD1 1 ATOM 2816 N N . ALA B 2 190 ? 14.061 -5.310 -0.444 1.00 97.16 ? 190 ALA B N 190 ALA B N 1 ATOM 2817 C CA . ALA B 2 190 ? 13.590 -4.891 -1.761 1.00 97.16 ? 190 ALA B CA 190 ALA B CA 1 ATOM 2818 C C . ALA B 2 190 ? 13.358 -3.384 -1.808 1.00 97.16 ? 190 ALA B C 190 ALA B C 1 ATOM 2819 O O . ALA B 2 190 ? 13.749 -2.718 -2.770 1.00 97.16 ? 190 ALA B O 190 ALA B O 1 ATOM 2820 C CB . ALA B 2 190 ? 12.308 -5.635 -2.129 1.00 97.16 ? 190 ALA B CB 190 ALA B CB 1 ATOM 2821 N N . MET B 2 191 ? 12.777 -2.867 -0.763 1.00 96.46 ? 191 MET B N 191 MET B N 1 ATOM 2822 C CA . MET B 2 191 ? 12.489 -1.438 -0.692 1.00 96.46 ? 191 MET B CA 191 MET B CA 1 ATOM 2823 C C . MET B 2 191 ? 13.778 -0.622 -0.690 1.00 96.46 ? 191 MET B C 191 MET B C 1 ATOM 2824 O O . MET B 2 191 ? 13.914 0.334 -1.455 1.00 96.46 ? 191 MET B O 191 MET B O 1 ATOM 2825 C CB . MET B 2 191 ? 11.665 -1.116 0.556 1.00 96.46 ? 191 MET B CB 191 MET B CB 1 ATOM 2826 C CG . MET B 2 191 ? 11.312 0.356 0.694 1.00 96.46 ? 191 MET B CG 191 MET B CG 1 ATOM 2827 S SD . MET B 2 191 ? 10.237 0.953 -0.668 1.00 96.46 ? 191 MET B SD 191 MET B SD 1 ATOM 2828 C CE . MET B 2 191 ? 10.645 2.720 -0.647 1.00 96.46 ? 191 MET B CE 191 MET B CE 1 ATOM 2829 N N . GLU B 2 192 ? 14.765 -0.990 0.095 1.00 95.63 ? 192 GLU B N 192 GLU B N 1 ATOM 2830 C CA . GLU B 2 192 ? 16.030 -0.270 0.207 1.00 95.63 ? 192 GLU B CA 192 GLU B CA 1 ATOM 2831 C C . GLU B 2 192 ? 16.827 -0.347 -1.092 1.00 95.63 ? 192 GLU B C 192 GLU B C 1 ATOM 2832 O O . GLU B 2 192 ? 17.476 0.623 -1.487 1.00 95.63 ? 192 GLU B O 192 GLU B O 1 ATOM 2833 C CB . GLU B 2 192 ? 16.862 -0.821 1.368 1.00 95.63 ? 192 GLU B CB 192 GLU B CB 1 ATOM 2834 C CG . GLU B 2 192 ? 16.301 -0.484 2.741 1.00 95.63 ? 192 GLU B CG 192 GLU B CG 1 ATOM 2835 C CD . GLU B 2 192 ? 16.183 1.012 2.990 1.00 95.63 ? 192 GLU B CD 192 GLU B CD 1 ATOM 2836 O OE1 . GLU B 2 192 ? 15.183 1.448 3.604 1.00 95.63 ? 192 GLU B OE1 192 GLU B OE1 1 ATOM 2837 O OE2 . GLU B 2 192 ? 17.098 1.753 2.568 1.00 95.63 ? 192 GLU B OE2 192 GLU B OE2 1 ATOM 2838 N N . THR B 2 193 ? 16.721 -1.465 -1.709 1.00 96.43 ? 193 THR B N 193 THR B N 1 ATOM 2839 C CA . THR B 2 193 ? 17.444 -1.662 -2.961 1.00 96.43 ? 193 THR B CA 193 THR B CA 1 ATOM 2840 C C . THR B 2 193 ? 16.840 -0.811 -4.074 1.00 96.43 ? 193 THR B C 193 THR B C 1 ATOM 2841 O O . THR B 2 193 ? 17.567 -0.192 -4.854 1.00 96.43 ? 193 THR B O 193 THR B O 1 ATOM 2842 C CB . THR B 2 193 ? 17.440 -3.143 -3.382 1.00 96.43 ? 193 THR B CB 193 THR B CB 1 ATOM 2843 O OG1 . THR B 2 193 ? 17.958 -3.940 -2.310 1.00 96.43 ? 193 THR B OG1 193 THR B OG1 1 ATOM 2844 C CG2 . THR B 2 193 ? 18.297 -3.364 -4.624 1.00 96.43 ? 193 THR B CG2 193 THR B CG2 1 ATOM 2845 N N . VAL B 2 194 ? 15.525 -0.779 -4.148 1.00 97.07 ? 194 VAL B N 194 VAL B N 1 ATOM 2846 C CA . VAL B 2 194 ? 14.844 -0.011 -5.185 1.00 97.07 ? 194 VAL B CA 194 VAL B CA 1 ATOM 2847 C C . VAL B 2 194 ? 15.100 1.480 -4.976 1.00 97.07 ? 194 VAL B C 194 VAL B C 1 ATOM 2848 O O . VAL B 2 194 ? 15.331 2.218 -5.937 1.00 97.07 ? 194 VAL B O 194 VAL B O 1 ATOM 2849 C CB . VAL B 2 194 ? 13.325 -0.294 -5.195 1.00 97.07 ? 194 VAL B CB 194 VAL B CB 1 ATOM 2850 C CG1 . VAL B 2 194 ? 12.600 0.682 -6.120 1.00 97.07 ? 194 VAL B CG1 194 VAL B CG1 1 ATOM 2851 C CG2 . VAL B 2 194 ? 13.055 -1.737 -5.617 1.00 97.07 ? 194 VAL B CG2 194 VAL B CG2 1 ATOM 2852 N N . VAL B 2 195 ? 15.109 1.934 -3.713 1.00 96.32 ? 195 VAL B N 195 VAL B N 1 ATOM 2853 C CA . VAL B 2 195 ? 15.404 3.329 -3.404 1.00 96.32 ? 195 VAL B CA 195 VAL B CA 1 ATOM 2854 C C . VAL B 2 195 ? 16.815 3.675 -3.873 1.00 96.32 ? 195 VAL B C 195 VAL B C 1 ATOM 2855 O O . VAL B 2 195 ? 17.026 4.703 -4.522 1.00 96.32 ? 195 VAL B O 195 VAL B O 1 ATOM 2856 C CB . VAL B 2 195 ? 15.257 3.620 -1.894 1.00 96.32 ? 195 VAL B CB 195 VAL B CB 1 ATOM 2857 C CG1 . VAL B 2 195 ? 15.821 4.998 -1.552 1.00 96.32 ? 195 VAL B CG1 195 VAL B CG1 1 ATOM 2858 C CG2 . VAL B 2 195 ? 13.793 3.518 -1.471 1.00 96.32 ? 195 VAL B CG2 195 VAL B CG2 1 ATOM 2859 N N . ALA B 2 196 ? 17.723 2.802 -3.597 1.00 95.63 ? 196 ALA B N 196 ALA B N 1 ATOM 2860 C CA . ALA B 2 196 ? 19.109 3.013 -4.005 1.00 95.63 ? 196 ALA B CA 196 ALA B CA 1 ATOM 2861 C C . ALA B 2 196 ? 19.243 2.985 -5.525 1.00 95.63 ? 196 ALA B C 196 ALA B C 1 ATOM 2862 O O . ALA B 2 196 ? 19.985 3.782 -6.104 1.00 95.63 ? 196 ALA B O 196 ALA B O 1 ATOM 2863 C CB . ALA B 2 196 ? 20.015 1.958 -3.376 1.00 95.63 ? 196 ALA B CB 196 ALA B CB 1 ATOM 2864 N N . LEU B 2 197 ? 18.515 2.065 -6.092 1.00 95.30 ? 197 LEU B N 197 LEU B N 1 ATOM 2865 C CA . LEU B 2 197 ? 18.529 1.940 -7.545 1.00 95.30 ? 197 LEU B CA 197 LEU B CA 1 ATOM 2866 C C . LEU B 2 197 ? 18.014 3.214 -8.205 1.00 95.30 ? 197 LEU B C 197 LEU B C 1 ATOM 2867 O O . LEU B 2 197 ? 18.606 3.700 -9.172 1.00 95.30 ? 197 LEU B O 197 LEU B O 1 ATOM 2868 C CB . LEU B 2 197 ? 17.681 0.744 -7.988 1.00 95.30 ? 197 LEU B CB 197 LEU B CB 1 ATOM 2869 C CG . LEU B 2 197 ? 17.617 0.479 -9.493 1.00 95.30 ? 197 LEU B CG 197 LEU B CG 1 ATOM 2870 C CD1 . LEU B 2 197 ? 18.993 0.089 -10.022 1.00 95.30 ? 197 LEU B CD1 197 LEU B CD1 1 ATOM 2871 C CD2 . LEU B 2 197 ? 16.592 -0.607 -9.802 1.00 95.30 ? 197 LEU B CD2 197 LEU B CD2 1 ATOM 2872 N N . LEU B 2 198 ? 16.933 3.779 -7.675 1.00 95.17 ? 198 LEU B N 198 LEU B N 1 ATOM 2873 C CA . LEU B 2 198 ? 16.355 4.998 -8.230 1.00 95.17 ? 198 LEU B CA 198 LEU B CA 1 ATOM 2874 C C . LEU B 2 198 ? 17.308 6.177 -8.062 1.00 95.17 ? 198 LEU B C 198 LEU B C 1 ATOM 2875 O O . LEU B 2 198 ? 17.330 7.086 -8.894 1.00 95.17 ? 198 LEU B O 198 LEU B O 1 ATOM 2876 C CB . LEU B 2 198 ? 15.015 5.310 -7.559 1.00 95.17 ? 198 LEU B CB 198 LEU B CB 1 ATOM 2877 C CG . LEU B 2 198 ? 13.848 4.388 -7.915 1.00 95.17 ? 198 LEU B CG 198 LEU B CG 1 ATOM 2878 C CD1 . LEU B 2 198 ? 12.593 4.803 -7.155 1.00 95.17 ? 198 LEU B CD1 198 LEU B CD1 1 ATOM 2879 C CD2 . LEU B 2 198 ? 13.596 4.400 -9.419 1.00 95.17 ? 198 LEU B CD2 198 LEU B CD2 1 ATOM 2880 N N . ALA B 2 199 ? 18.071 6.161 -7.020 1.00 94.08 ? 199 ALA B N 199 ALA B N 1 ATOM 2881 C CA . ALA B 2 199 ? 19.085 7.190 -6.804 1.00 94.08 ? 199 ALA B CA 199 ALA B CA 1 ATOM 2882 C C . ALA B 2 199 ? 20.147 7.152 -7.900 1.00 94.08 ? 199 ALA B C 199 ALA B C 1 ATOM 2883 O O . ALA B 2 199 ? 20.715 8.187 -8.258 1.00 94.08 ? 199 ALA B O 199 ALA B O 1 ATOM 2884 C CB . ALA B 2 199 ? 19.734 7.018 -5.433 1.00 94.08 ? 199 ALA B CB 199 ALA B CB 1 ATOM 2885 N N . CYS B 2 200 ? 20.396 5.977 -8.425 1.00 93.37 ? 200 CYS B N 200 CYS B N 1 ATOM 2886 C CA . CYS B 2 200 ? 21.384 5.802 -9.484 1.00 93.37 ? 200 CYS B CA 200 CYS B CA 1 ATOM 2887 C C . CYS B 2 200 ? 20.906 6.434 -10.785 1.00 93.37 ? 200 CYS B C 200 CYS B C 1 ATOM 2888 O O . CYS B 2 200 ? 21.706 6.687 -11.688 1.00 93.37 ? 200 CYS B O 200 CYS B O 1 ATOM 2889 C CB . CYS B 2 200 ? 21.676 4.318 -9.704 1.00 93.37 ? 200 CYS B CB 200 CYS B CB 1 ATOM 2890 S SG . CYS B 2 200 ? 22.639 3.561 -8.377 1.00 93.37 ? 200 CYS B SG 200 CYS B SG 1 ATOM 2891 N N . ALA B 2 201 ? 19.598 6.674 -10.828 1.00 92.58 ? 201 ALA B N 201 ALA B N 1 ATOM 2892 C CA . ALA B 2 201 ? 19.064 7.359 -12.002 1.00 92.58 ? 201 ALA B CA 201 ALA B CA 1 ATOM 2893 C C . ALA B 2 201 ? 19.586 8.790 -12.087 1.00 92.58 ? 201 ALA B C 201 ALA B C 1 ATOM 2894 O O . ALA B 2 201 ? 19.690 9.356 -13.178 1.00 92.58 ? 201 ALA B O 201 ALA B O 1 ATOM 2895 C CB . ALA B 2 201 ? 17.538 7.353 -11.973 1.00 92.58 ? 201 ALA B CB 201 ALA B CB 1 ATOM 2896 N N . LEU B 2 202 ? 19.968 9.397 -10.979 1.00 92.24 ? 202 LEU B N 202 LEU B N 1 ATOM 2897 C CA . LEU B 2 202 ? 20.511 10.750 -10.914 1.00 92.24 ? 202 LEU B CA 202 LEU B CA 1 ATOM 2898 C C . LEU B 2 202 ? 21.988 10.761 -11.294 1.00 92.24 ? 202 LEU B C 202 LEU B C 1 ATOM 2899 O O . LEU B 2 202 ? 22.478 11.736 -11.869 1.00 92.24 ? 202 LEU B O 202 LEU B O 1 ATOM 2900 C CB . LEU B 2 202 ? 20.329 11.333 -9.510 1.00 92.24 ? 202 LEU B CB 202 LEU B CB 1 ATOM 2901 C CG . LEU B 2 202 ? 18.888 11.547 -9.046 1.00 92.24 ? 202 LEU B CG 202 LEU B CG 1 ATOM 2902 C CD1 . LEU B 2 202 ? 18.853 11.872 -7.557 1.00 92.24 ? 202 LEU B CD1 202 LEU B CD1 1 ATOM 2903 C CD2 . LEU B 2 202 ? 18.223 12.654 -9.857 1.00 92.24 ? 202 LEU B CD2 202 LEU B CD2 1 ATOM 2904 N N . THR B 2 203 ? 22.675 9.654 -10.992 1.00 89.85 ? 203 THR B N 203 THR B N 1 ATOM 2905 C CA . THR B 2 203 ? 24.092 9.487 -11.295 1.00 89.85 ? 203 THR B CA 203 THR B CA 1 ATOM 2906 C C . THR B 2 203 ? 24.348 8.135 -11.955 1.00 89.85 ? 203 THR B C 203 THR B C 1 ATOM 2907 O O . THR B 2 203 ? 24.781 7.189 -11.295 1.00 89.85 ? 203 THR B O 203 THR B O 1 ATOM 2908 C CB . THR B 2 203 ? 24.953 9.613 -10.025 1.00 89.85 ? 203 THR B CB 203 THR B CB 1 ATOM 2909 O OG1 . THR B 2 203 ? 24.471 8.696 -9.035 1.00 89.85 ? 203 THR B OG1 203 THR B OG1 1 ATOM 2910 C CG2 . THR B 2 203 ? 24.897 11.028 -9.460 1.00 89.85 ? 203 THR B CG2 203 THR B CG2 1 ATOM 2911 N N . PRO B 2 204 ? 24.022 8.046 -13.216 1.00 87.82 ? 204 PRO B N 204 PRO B N 1 ATOM 2912 C CA . PRO B 2 204 ? 24.107 6.768 -13.927 1.00 87.82 ? 204 PRO B CA 204 PRO B CA 1 ATOM 2913 C C . PRO B 2 204 ? 25.514 6.174 -13.907 1.00 87.82 ? 204 PRO B C 204 PRO B C 1 ATOM 2914 O O . PRO B 2 204 ? 25.679 4.963 -14.073 1.00 87.82 ? 204 PRO B O 204 PRO B O 1 ATOM 2915 C CB . PRO B 2 204 ? 23.687 7.130 -15.354 1.00 87.82 ? 204 PRO B CB 204 PRO B CB 1 ATOM 2916 C CG . PRO B 2 204 ? 23.911 8.604 -15.456 1.00 87.82 ? 204 PRO B CG 204 PRO B CG 1 ATOM 2917 C CD . PRO B 2 204 ? 23.723 9.210 -14.095 1.00 87.82 ? 204 PRO B CD 204 PRO B CD 1 ATOM 2918 N N . GLU B 2 205 ? 26.567 6.974 -13.626 1.00 89.19 ? 205 GLU B N 205 GLU B N 1 ATOM 2919 C CA . GLU B 2 205 ? 27.951 6.513 -13.578 1.00 89.19 ? 205 GLU B CA 205 GLU B CA 1 ATOM 2920 C C . GLU B 2 205 ? 28.171 5.549 -12.415 1.00 89.19 ? 205 GLU B C 205 GLU B C 1 ATOM 2921 O O . GLU B 2 205 ? 29.061 4.698 -12.467 1.00 89.19 ? 205 GLU B O 205 GLU B O 1 ATOM 2922 C CB . GLU B 2 205 ? 28.910 7.700 -13.466 1.00 89.19 ? 205 GLU B CB 205 GLU B CB 1 ATOM 2923 C CG . GLU B 2 205 ? 28.850 8.653 -14.650 1.00 89.19 ? 205 GLU B CG 205 GLU B CG 1 ATOM 2924 C CD . GLU B 2 205 ? 29.744 9.872 -14.486 1.00 89.19 ? 205 GLU B CD 205 GLU B CD 1 ATOM 2925 O OE1 . GLU B 2 205 ? 29.823 10.698 -15.424 1.00 89.19 ? 205 GLU B OE1 205 GLU B OE1 1 ATOM 2926 O OE2 . GLU B 2 205 ? 30.372 10.002 -13.411 1.00 89.19 ? 205 GLU B OE2 205 GLU B OE2 1 ATOM 2927 N N . LYS B 2 206 ? 27.341 5.658 -11.458 1.00 89.75 ? 206 LYS B N 206 LYS B N 1 ATOM 2928 C CA . LYS B 2 206 ? 27.514 4.873 -10.239 1.00 89.75 ? 206 LYS B CA 206 LYS B CA 1 ATOM 2929 C C . LYS B 2 206 ? 26.715 3.574 -10.304 1.00 89.75 ? 206 LYS B C 206 LYS B C 1 ATOM 2930 O O . LYS B 2 206 ? 26.728 2.784 -9.358 1.00 89.75 ? 206 LYS B O 206 LYS B O 1 ATOM 2931 C CB . LYS B 2 206 ? 27.095 5.686 -9.013 1.00 89.75 ? 206 LYS B CB 206 LYS B CB 1 ATOM 2932 C CG . LYS B 2 206 ? 27.893 6.966 -8.817 1.00 89.75 ? 206 LYS B CG 206 LYS B CG 1 ATOM 2933 C CD . LYS B 2 206 ? 29.257 6.685 -8.199 1.00 89.75 ? 206 LYS B CD 206 LYS B CD 1 ATOM 2934 C CE . LYS B 2 206 ? 30.053 7.967 -7.993 1.00 89.75 ? 206 LYS B CE 206 LYS B CE 1 ATOM 2935 N NZ . LYS B 2 206 ? 31.417 7.690 -7.451 1.00 89.75 ? 206 LYS B NZ 206 LYS B NZ 1 ATOM 2936 N N . LEU B 2 207 ? 25.996 3.377 -11.349 1.00 90.79 ? 207 LEU B N 207 LEU B N 1 ATOM 2937 C CA . LEU B 2 207 ? 25.233 2.148 -11.534 1.00 90.79 ? 207 LEU B CA 207 LEU B CA 1 ATOM 2938 C C . LEU B 2 207 ? 26.163 0.951 -11.704 1.00 90.79 ? 207 LEU B C 207 LEU B C 1 ATOM 2939 O O . LEU B 2 207 ? 27.040 0.959 -12.571 1.00 90.79 ? 207 LEU B O 207 LEU B O 1 ATOM 2940 C CB . LEU B 2 207 ? 24.310 2.268 -12.749 1.00 90.79 ? 207 LEU B CB 207 LEU B CB 1 ATOM 2941 C CG . LEU B 2 207 ? 23.381 1.082 -13.015 1.00 90.79 ? 207 LEU B CG 207 LEU B CG 1 ATOM 2942 C CD1 . LEU B 2 207 ? 22.363 0.943 -11.887 1.00 90.79 ? 207 LEU B CD1 207 LEU B CD1 1 ATOM 2943 C CD2 . LEU B 2 207 ? 22.679 1.243 -14.359 1.00 90.79 ? 207 LEU B CD2 207 LEU B CD2 1 ATOM 2944 N N . PRO B 2 208 ? 26.029 -0.030 -10.804 1.00 90.29 ? 208 PRO B N 208 PRO B N 1 ATOM 2945 C CA . PRO B 2 208 ? 26.879 -1.216 -10.936 1.00 90.29 ? 208 PRO B CA 208 PRO B CA 1 ATOM 2946 C C . PRO B 2 208 ? 26.782 -1.860 -12.317 1.00 90.29 ? 208 PRO B C 208 PRO B C 1 ATOM 2947 O O . PRO B 2 208 ? 25.693 -1.937 -12.891 1.00 90.29 ? 208 PRO B O 208 PRO B O 1 ATOM 2948 C CB . PRO B 2 208 ? 26.341 -2.157 -9.855 1.00 90.29 ? 208 PRO B CB 208 PRO B CB 1 ATOM 2949 C CG . PRO B 2 208 ? 25.690 -1.257 -8.855 1.00 90.29 ? 208 PRO B CG 208 PRO B CG 1 ATOM 2950 C CD . PRO B 2 208 ? 25.103 -0.081 -9.581 1.00 90.29 ? 208 PRO B CD 208 PRO B CD 1 ATOM 2951 N N . ALA B 2 209 ? 27.851 -2.304 -12.818 1.00 88.73 ? 209 ALA B N 209 ALA B N 1 ATOM 2952 C CA . ALA B 2 209 ? 27.951 -2.895 -14.150 1.00 88.73 ? 209 ALA B CA 209 ALA B CA 1 ATOM 2953 C C . ALA B 2 209 ? 27.108 -4.163 -14.252 1.00 88.73 ? 209 ALA B C 209 ALA B C 1 ATOM 2954 O O . ALA B 2 209 ? 26.587 -4.485 -15.322 1.00 88.73 ? 209 ALA B O 209 ALA B O 1 ATOM 2955 C CB . ALA B 2 209 ? 29.408 -3.199 -14.489 1.00 88.73 ? 209 ALA B CB 209 ALA B CB 1 ATOM 2956 N N . SER B 2 210 ? 26.959 -4.817 -13.110 1.00 87.33 ? 210 SER B N 210 SER B N 1 ATOM 2957 C CA . SER B 2 210 ? 26.200 -6.063 -13.064 1.00 87.33 ? 210 SER B CA 210 SER B CA 1 ATOM 2958 C C . SER B 2 210 ? 24.720 -5.820 -13.341 1.00 87.33 ? 210 SER B C 210 SER B C 1 ATOM 2959 O O . SER B 2 210 ? 24.016 -6.716 -13.808 1.00 87.33 ? 210 SER B O 210 SER B O 1 ATOM 2960 C CB . SER B 2 210 ? 26.368 -6.742 -11.704 1.00 87.33 ? 210 SER B CB 210 SER B CB 1 ATOM 2961 O OG . SER B 2 210 ? 25.978 -5.872 -10.655 1.00 87.33 ? 210 SER B OG 210 SER B OG 1 ATOM 2962 N N . LEU B 2 211 ? 24.300 -4.567 -13.108 1.00 85.83 ? 211 LEU B N 211 LEU B N 1 ATOM 2963 C CA . LEU B 2 211 ? 22.890 -4.219 -13.249 1.00 85.83 ? 211 LEU B CA 211 LEU B CA 1 ATOM 2964 C C . LEU B 2 211 ? 22.645 -3.461 -14.550 1.00 85.83 ? 211 LEU B C 211 LEU B C 1 ATOM 2965 O O . LEU B 2 211 ? 21.533 -3.477 -15.082 1.00 85.83 ? 211 LEU B O 211 LEU B O 1 ATOM 2966 C CB . LEU B 2 211 ? 22.423 -3.377 -12.059 1.00 85.83 ? 211 LEU B CB 211 LEU B CB 1 ATOM 2967 C CG . LEU B 2 211 ? 22.410 -4.075 -10.698 1.00 85.83 ? 211 LEU B CG 211 LEU B CG 1 ATOM 2968 C CD1 . LEU B 2 211 ? 22.077 -3.078 -9.594 1.00 85.83 ? 211 LEU B CD1 211 LEU B CD1 1 ATOM 2969 C CD2 . LEU B 2 211 ? 21.416 -5.231 -10.700 1.00 85.83 ? 211 LEU B CD2 211 LEU B CD2 1 ATOM 2970 N N . GLY B 2 212 ? 23.658 -2.716 -15.035 1.00 69.27 ? 212 GLY B N 212 GLY B N 1 ATOM 2971 C CA . GLY B 2 212 ? 23.623 -1.717 -16.090 1.00 69.27 ? 212 GLY B CA 212 GLY B CA 1 ATOM 2972 C C . GLY B 2 212 ? 23.731 -2.314 -17.481 1.00 69.27 ? 212 GLY B C 212 GLY B C 1 ATOM 2973 O O . GLY B 2 212 ? 23.553 -1.612 -18.479 1.00 69.27 ? 212 GLY B O 212 GLY B O 1 ATOM 2974 N N . GLY B 2 213 ? 23.142 -3.554 -17.697 1.00 67.33 ? 213 GLY B N 213 GLY B N 1 ATOM 2975 C CA . GLY B 2 213 ? 23.192 -4.123 -19.034 1.00 67.33 ? 213 GLY B CA 213 GLY B CA 1 ATOM 2976 C C . GLY B 2 213 ? 23.615 -3.123 -20.093 1.00 67.33 ? 213 GLY B C 213 GLY B C 1 ATOM 2977 O O . GLY B 2 213 ? 24.565 -2.362 -19.892 1.00 67.33 ? 213 GLY B O 213 GLY B O 1 ATOM 2978 N N . THR B 2 214 ? 22.993 -3.117 -21.415 1.00 59.72 ? 214 THR B N 214 THR B N 1 ATOM 2979 C CA . THR B 2 214 ? 23.239 -2.330 -22.619 1.00 59.72 ? 214 THR B CA 214 THR B CA 1 ATOM 2980 C C . THR B 2 214 ? 22.700 -0.912 -22.457 1.00 59.72 ? 214 THR B C 214 THR B C 1 ATOM 2981 O O . THR B 2 214 ? 23.234 0.032 -23.043 1.00 59.72 ? 214 THR B O 214 THR B O 1 ATOM 2982 C CB . THR B 2 214 ? 22.599 -2.987 -23.856 1.00 59.72 ? 214 THR B CB 214 THR B CB 1 ATOM 2983 O OG1 . THR B 2 214 ? 21.405 -3.673 -23.462 1.00 59.72 ? 214 THR B OG1 214 THR B OG1 1 ATOM 2984 C CG2 . THR B 2 214 ? 23.554 -3.984 -24.505 1.00 59.72 ? 214 THR B CG2 214 THR B CG2 1 ATOM 2985 N N . SER B 2 215 ? 21.776 -0.703 -21.542 1.00 63.23 ? 215 SER B N 215 SER B N 1 ATOM 2986 C CA . SER B 2 215 ? 21.132 0.592 -21.347 1.00 63.23 ? 215 SER B CA 215 SER B CA 1 ATOM 2987 C C . SER B 2 215 ? 21.659 1.288 -20.096 1.00 63.23 ? 215 SER B C 215 SER B C 1 ATOM 2988 O O . SER B 2 215 ? 21.928 0.638 -19.084 1.00 63.23 ? 215 SER B O 215 SER B O 1 ATOM 2989 C CB . SER B 2 215 ? 19.615 0.428 -21.248 1.00 63.23 ? 215 SER B CB 215 SER B CB 1 ATOM 2990 O OG . SER B 2 215 ? 19.267 -0.371 -20.131 1.00 63.23 ? 215 SER B OG 215 SER B OG 1 ATOM 2991 N N . SER B 2 216 ? 22.344 2.416 -20.229 1.00 70.44 ? 216 SER B N 216 SER B N 1 ATOM 2992 C CA . SER B 2 216 ? 22.911 3.247 -19.173 1.00 70.44 ? 216 SER B CA 216 SER B CA 1 ATOM 2993 C C . SER B 2 216 ? 21.820 3.827 -18.280 1.00 70.44 ? 216 SER B C 216 SER B C 1 ATOM 2994 O O . SER B 2 216 ? 22.113 4.485 -17.279 1.00 70.44 ? 216 SER B O 216 SER B O 1 ATOM 2995 C CB . SER B 2 216 ? 23.748 4.379 -19.771 1.00 70.44 ? 216 SER B CB 216 SER B CB 1 ATOM 2996 O OG . SER B 2 216 ? 22.931 5.273 -20.507 1.00 70.44 ? 216 SER B OG 216 SER B OG 1 ATOM 2997 N N . GLY B 2 217 ? 20.586 3.350 -18.331 1.00 82.36 ? 217 GLY B N 217 GLY B N 1 ATOM 2998 C CA . GLY B 2 217 ? 19.559 3.942 -17.489 1.00 82.36 ? 217 GLY B CA 217 GLY B CA 1 ATOM 2999 C C . GLY B 2 217 ? 18.774 2.916 -16.694 1.00 82.36 ? 217 GLY B C 217 GLY B C 1 ATOM 3000 O O . GLY B 2 217 ? 18.953 1.711 -16.878 1.00 82.36 ? 217 GLY B O 217 GLY B O 1 ATOM 3001 N N . ILE B 2 218 ? 18.152 3.448 -15.666 1.00 91.32 ? 218 ILE B N 218 ILE B N 1 ATOM 3002 C CA . ILE B 2 218 ? 17.296 2.618 -14.825 1.00 91.32 ? 218 ILE B CA 218 ILE B CA 1 ATOM 3003 C C . ILE B 2 218 ? 15.945 2.414 -15.506 1.00 91.32 ? 218 ILE B C 218 ILE B C 1 ATOM 3004 O O . ILE B 2 218 ? 15.186 3.368 -15.692 1.00 91.32 ? 218 ILE B O 218 ILE B O 1 ATOM 3005 C CB . ILE B 2 218 ? 17.102 3.243 -13.425 1.00 91.32 ? 218 ILE B CB 218 ILE B CB 1 ATOM 3006 C CG1 . ILE B 2 218 ? 18.459 3.474 -12.750 1.00 91.32 ? 218 ILE B CG1 218 ILE B CG1 1 ATOM 3007 C CG2 . ILE B 2 218 ? 16.202 2.357 -12.558 1.00 91.32 ? 218 ILE B CG2 218 ILE B CG2 1 ATOM 3008 C CD1 . ILE B 2 218 ? 19.266 2.202 -12.533 1.00 91.32 ? 218 ILE B CD1 218 ILE B CD1 1 ATOM 3009 N N . THR B 2 219 ? 15.666 1.179 -15.908 1.00 92.08 ? 219 THR B N 219 THR B N 1 ATOM 3010 C CA . THR B 2 219 ? 14.424 0.862 -16.605 1.00 92.08 ? 219 THR B CA 219 THR B CA 1 ATOM 3011 C C . THR B 2 219 ? 13.454 0.135 -15.679 1.00 92.08 ? 219 THR B C 219 THR B C 1 ATOM 3012 O O . THR B 2 219 ? 13.848 -0.348 -14.615 1.00 92.08 ? 219 THR B O 219 THR B O 1 ATOM 3013 C CB . THR B 2 219 ? 14.689 0.002 -17.854 1.00 92.08 ? 219 THR B CB 219 THR B CB 1 ATOM 3014 O OG1 . THR B 2 219 ? 15.292 -1.235 -17.456 1.00 92.08 ? 219 THR B OG1 219 THR B OG1 1 ATOM 3015 C CG2 . THR B 2 219 ? 15.619 0.717 -18.828 1.00 92.08 ? 219 THR B CG2 219 THR B CG2 1 ATOM 3016 N N . GLY B 2 220 ? 12.155 0.205 -15.982 1.00 92.12 ? 220 GLY B N 220 GLY B N 1 ATOM 3017 C CA . GLY B 2 220 ? 11.138 -0.533 -15.252 1.00 92.12 ? 220 GLY B CA 220 GLY B CA 1 ATOM 3018 C C . GLY B 2 220 ? 11.400 -2.027 -15.208 1.00 92.12 ? 220 GLY B C 220 GLY B C 1 ATOM 3019 O O . GLY B 2 220 ? 11.136 -2.679 -14.196 1.00 92.12 ? 220 GLY B O 220 GLY B O 1 ATOM 3020 N N . GLN B 2 221 ? 11.971 -2.567 -16.247 1.00 91.93 ? 221 GLN B N 221 GLN B N 1 ATOM 3021 C CA . GLN B 2 221 ? 12.299 -3.988 -16.312 1.00 91.93 ? 221 GLN B CA 221 GLN B CA 1 ATOM 3022 C C . GLN B 2 221 ? 13.338 -4.361 -15.259 1.00 91.93 ? 221 GLN B C 221 GLN B C 1 ATOM 3023 O O . GLN B 2 221 ? 13.251 -5.425 -14.643 1.00 91.93 ? 221 GLN B O 221 GLN B O 1 ATOM 3024 C CB . GLN B 2 221 ? 12.807 -4.359 -17.706 1.00 91.93 ? 221 GLN B CB 221 GLN B CB 1 ATOM 3025 C CG . GLN B 2 221 ? 11.722 -4.366 -18.774 1.00 91.93 ? 221 GLN B CG 221 GLN B CG 1 ATOM 3026 C CD . GLN B 2 221 ? 12.264 -4.664 -20.160 1.00 91.93 ? 221 GLN B CD 221 GLN B CD 1 ATOM 3027 O OE1 . GLN B 2 221 ? 13.480 -4.743 -20.361 1.00 91.93 ? 221 GLN B OE1 221 GLN B OE1 1 ATOM 3028 N NE2 . GLN B 2 221 ? 11.367 -4.830 -21.125 1.00 91.93 ? 221 GLN B NE2 221 GLN B NE2 1 ATOM 3029 N N . LEU B 2 222 ? 14.320 -3.457 -15.163 1.00 93.57 ? 222 LEU B N 222 LEU B N 1 ATOM 3030 C CA . LEU B 2 222 ? 15.361 -3.675 -14.165 1.00 93.57 ? 222 LEU B CA 222 LEU B CA 1 ATOM 3031 C C . LEU B 2 222 ? 14.776 -3.666 -12.757 1.00 93.57 ? 222 LEU B C 222 LEU B C 1 ATOM 3032 O O . LEU B 2 222 ? 15.128 -4.509 -11.928 1.00 93.57 ? 222 LEU B O 222 LEU B O 1 ATOM 3033 C CB . LEU B 2 222 ? 16.450 -2.605 -14.284 1.00 93.57 ? 222 LEU B CB 222 LEU B CB 1 ATOM 3034 C CG . LEU B 2 222 ? 17.627 -2.725 -13.314 1.00 93.57 ? 222 LEU B CG 222 LEU B CG 1 ATOM 3035 C CD1 . LEU B 2 222 ? 18.313 -4.077 -13.477 1.00 93.57 ? 222 LEU B CD1 222 LEU B CD1 1 ATOM 3036 C CD2 . LEU B 2 222 ? 18.618 -1.587 -13.533 1.00 93.57 ? 222 LEU B CD2 222 LEU B CD2 1 ATOM 3037 N N . ILE B 2 223 ? 13.876 -2.756 -12.486 1.00 95.63 ? 223 ILE B N 223 ILE B N 1 ATOM 3038 C CA . ILE B 2 223 ? 13.217 -2.661 -11.188 1.00 95.63 ? 223 ILE B CA 223 ILE B CA 1 ATOM 3039 C C . ILE B 2 223 ? 12.474 -3.961 -10.890 1.00 95.63 ? 223 ILE B C 223 ILE B C 1 ATOM 3040 O O . ILE B 2 223 ? 12.596 -4.517 -9.796 1.00 95.63 ? 223 ILE B O 223 ILE B O 1 ATOM 3041 C CB . ILE B 2 223 ? 12.243 -1.463 -11.136 1.00 95.63 ? 223 ILE B CB 223 ILE B CB 1 ATOM 3042 C CG1 . ILE B 2 223 ? 13.010 -0.144 -11.280 1.00 95.63 ? 223 ILE B CG1 223 ILE B CG1 1 ATOM 3043 C CG2 . ILE B 2 223 ? 11.430 -1.484 -9.838 1.00 95.63 ? 223 ILE B CG2 223 ILE B CG2 1 ATOM 3044 C CD1 . ILE B 2 223 ? 12.117 1.077 -11.447 1.00 95.63 ? 223 ILE B CD1 223 ILE B CD1 1 ATOM 3045 N N . ARG B 2 224 ? 11.705 -4.464 -11.812 1.00 95.09 ? 224 ARG B N 224 ARG B N 1 ATOM 3046 C CA . ARG B 2 224 ? 10.953 -5.703 -11.647 1.00 95.09 ? 224 ARG B CA 224 ARG B CA 1 ATOM 3047 C C . ARG B 2 224 ? 11.888 -6.881 -11.392 1.00 95.09 ? 224 ARG B C 224 ARG B C 1 ATOM 3048 O O . ARG B 2 224 ? 11.647 -7.688 -10.492 1.00 95.09 ? 224 ARG B O 224 ARG B O 1 ATOM 3049 C CB . ARG B 2 224 ? 10.089 -5.977 -12.880 1.00 95.09 ? 224 ARG B CB 224 ARG B CB 1 ATOM 3050 C CG . ARG B 2 224 ? 9.189 -7.194 -12.743 1.00 95.09 ? 224 ARG B CG 224 ARG B CG 1 ATOM 3051 C CD . ARG B 2 224 ? 8.287 -7.368 -13.958 1.00 95.09 ? 224 ARG B CD 224 ARG B CD 1 ATOM 3052 N NE . ARG B 2 224 ? 7.403 -6.220 -14.141 1.00 95.09 ? 224 ARG B NE 224 ARG B NE 1 ATOM 3053 C CZ . ARG B 2 224 ? 6.291 -6.001 -13.446 1.00 95.09 ? 224 ARG B CZ 224 ARG B CZ 1 ATOM 3054 N NH1 . ARG B 2 224 ? 5.902 -6.851 -12.502 1.00 95.09 ? 224 ARG B NH1 224 ARG B NH1 1 ATOM 3055 N NH2 . ARG B 2 224 ? 5.561 -4.924 -13.695 1.00 95.09 ? 224 ARG B NH2 224 ARG B NH2 1 ATOM 3056 N N . THR B 2 225 ? 12.952 -6.982 -12.200 1.00 94.14 ? 225 THR B N 225 THR B N 1 ATOM 3057 C CA . THR B 2 225 ? 13.894 -8.092 -12.102 1.00 94.14 ? 225 THR B CA 225 THR B CA 1 ATOM 3058 C C . THR B 2 225 ? 14.525 -8.145 -10.714 1.00 94.14 ? 225 THR B C 225 THR B C 1 ATOM 3059 O O . THR B 2 225 ? 14.675 -9.224 -10.136 1.00 94.14 ? 225 THR B O 225 THR B O 1 ATOM 3060 C CB . THR B 2 225 ? 15.001 -7.981 -13.168 1.00 94.14 ? 225 THR B CB 225 THR B CB 1 ATOM 3061 O OG1 . THR B 2 225 ? 14.403 -7.985 -14.471 1.00 94.14 ? 225 THR B OG1 225 THR B OG1 1 ATOM 3062 C CG2 . THR B 2 225 ? 15.980 -9.145 -13.067 1.00 94.14 ? 225 THR B CG2 225 THR B CG2 1 ATOM 3063 N N . ILE B 2 226 ? 14.904 -7.011 -10.209 1.00 95.56 ? 226 ILE B N 226 ILE B N 1 ATOM 3064 C CA . ILE B 2 226 ? 15.550 -6.927 -8.904 1.00 95.56 ? 226 ILE B CA 226 ILE B CA 1 ATOM 3065 C C . ILE B 2 226 ? 14.578 -7.381 -7.817 1.00 95.56 ? 226 ILE B C 226 ILE B C 1 ATOM 3066 O O . ILE B 2 226 ? 14.920 -8.220 -6.980 1.00 95.56 ? 226 ILE B O 226 ILE B O 1 ATOM 3067 C CB . ILE B 2 226 ? 16.051 -5.495 -8.611 1.00 95.56 ? 226 ILE B CB 226 ILE B CB 1 ATOM 3068 C CG1 . ILE B 2 226 ? 17.257 -5.160 -9.496 1.00 95.56 ? 226 ILE B CG1 226 ILE B CG1 1 ATOM 3069 C CG2 . ILE B 2 226 ? 16.398 -5.337 -7.128 1.00 95.56 ? 226 ILE B CG2 226 ILE B CG2 1 ATOM 3070 C CD1 . ILE B 2 226 ? 17.721 -3.714 -9.388 1.00 95.56 ? 226 ILE B CD1 226 ILE B CD1 1 ATOM 3071 N N . VAL B 2 227 ? 13.381 -6.846 -7.846 1.00 97.10 ? 227 VAL B N 227 VAL B N 1 ATOM 3072 C CA . VAL B 2 227 ? 12.388 -7.171 -6.827 1.00 97.10 ? 227 VAL B CA 227 VAL B CA 1 ATOM 3073 C C . VAL B 2 227 ? 12.027 -8.652 -6.910 1.00 97.10 ? 227 VAL B C 227 VAL B C 1 ATOM 3074 O O . VAL B 2 227 ? 11.946 -9.337 -5.888 1.00 97.10 ? 227 VAL B O 227 VAL B O 1 ATOM 3075 C CB . VAL B 2 227 ? 11.117 -6.304 -6.975 1.00 97.10 ? 227 VAL B CB 227 VAL B CB 1 ATOM 3076 C CG1 . VAL B 2 227 ? 10.031 -6.767 -6.006 1.00 97.10 ? 227 VAL B CG1 227 VAL B CG1 1 ATOM 3077 C CG2 . VAL B 2 227 ? 11.448 -4.830 -6.747 1.00 97.10 ? 227 VAL B CG2 227 VAL B CG2 1 ATOM 3078 N N . ASP B 2 228 ? 11.830 -9.185 -8.130 1.00 95.40 ? 228 ASP B N 228 ASP B N 1 ATOM 3079 C CA . ASP B 2 228 ? 11.479 -10.587 -8.333 1.00 95.40 ? 228 ASP B CA 228 ASP B CA 1 ATOM 3080 C C . ASP B 2 228 ? 12.599 -11.509 -7.854 1.00 95.40 ? 228 ASP B C 228 ASP B C 1 ATOM 3081 O O . ASP B 2 228 ? 12.336 -12.577 -7.297 1.00 95.40 ? 228 ASP B O 228 ASP B O 1 ATOM 3082 C CB . ASP B 2 228 ? 11.171 -10.856 -9.807 1.00 95.40 ? 228 ASP B CB 228 ASP B CB 1 ATOM 3083 C CG . ASP B 2 228 ? 9.830 -10.294 -10.245 1.00 95.40 ? 228 ASP B CG 228 ASP B CG 1 ATOM 3084 O OD1 . ASP B 2 228 ? 9.030 -9.880 -9.378 1.00 95.40 ? 228 ASP B OD1 228 ASP B OD1 1 ATOM 3085 O OD2 . ASP B 2 228 ? 9.569 -10.267 -11.467 1.00 95.40 ? 228 ASP B OD2 228 ASP B OD2 1 ATOM 3086 N N . THR B 2 229 ? 13.828 -11.081 -8.065 1.00 94.72 ? 229 THR B N 229 THR B N 1 ATOM 3087 C CA . THR B 2 229 ? 14.975 -11.874 -7.637 1.00 94.72 ? 229 THR B CA 229 THR B CA 1 ATOM 3088 C C . THR B 2 229 ? 15.053 -11.935 -6.115 1.00 94.72 ? 229 THR B C 229 THR B C 1 ATOM 3089 O O . THR B 2 229 ? 15.319 -12.994 -5.543 1.00 94.72 ? 229 THR B O 229 THR B O 1 ATOM 3090 C CB . THR B 2 229 ? 16.290 -11.304 -8.199 1.00 94.72 ? 229 THR B CB 229 THR B CB 1 ATOM 3091 O OG1 . THR B 2 229 ? 16.217 -11.270 -9.630 1.00 94.72 ? 229 THR B OG1 229 THR B OG1 1 ATOM 3092 C CG2 . THR B 2 229 ? 17.483 -12.159 -7.783 1.00 94.72 ? 229 THR B CG2 229 THR B CG2 1 ATOM 3093 N N . ILE B 2 230 ? 14.807 -10.876 -5.443 1.00 96.25 ? 230 ILE B N 230 ILE B N 1 ATOM 3094 C CA . ILE B 2 230 ? 14.811 -10.827 -3.985 1.00 96.25 ? 230 ILE B CA 230 ILE B CA 1 ATOM 3095 C C . ILE B 2 230 ? 13.681 -11.696 -3.437 1.00 96.25 ? 230 ILE B C 230 ILE B C 1 ATOM 3096 O O . ILE B 2 230 ? 13.880 -12.458 -2.488 1.00 96.25 ? 230 ILE B O 230 ILE B O 1 ATOM 3097 C CB . ILE B 2 230 ? 14.672 -9.378 -3.468 1.00 96.25 ? 230 ILE B CB 230 ILE B CB 1 ATOM 3098 C CG1 . ILE B 2 230 ? 15.916 -8.560 -3.832 1.00 96.25 ? 230 ILE B CG1 230 ILE B CG1 1 ATOM 3099 C CG2 . ILE B 2 230 ? 14.432 -9.366 -1.955 1.00 96.25 ? 230 ILE B CG2 230 ILE B CG2 1 ATOM 3100 C CD1 . ILE B 2 230 ? 15.790 -7.073 -3.528 1.00 96.25 ? 230 ILE B CD1 230 ILE B CD1 1 ATOM 3101 N N . ALA B 2 231 ? 12.492 -11.555 -4.047 1.00 95.62 ? 231 ALA B N 231 ALA B N 1 ATOM 3102 C CA . ALA B 2 231 ? 11.348 -12.358 -3.622 1.00 95.62 ? 231 ALA B CA 231 ALA B CA 1 ATOM 3103 C C . ALA B 2 231 ? 11.647 -13.849 -3.747 1.00 95.62 ? 231 ALA B C 231 ALA B C 1 ATOM 3104 O O . ALA B 2 231 ? 11.348 -14.627 -2.838 1.00 95.62 ? 231 ALA B O 231 ALA B O 1 ATOM 3105 C CB . ALA B 2 231 ? 10.111 -11.996 -4.440 1.00 95.62 ? 231 ALA B CB 231 ALA B CB 1 ATOM 3106 N N . ARG B 2 232 ? 12.303 -14.240 -4.824 1.00 93.10 ? 232 ARG B N 232 ARG B N 1 ATOM 3107 C CA . ARG B 2 232 ? 12.648 -15.636 -5.072 1.00 93.10 ? 232 ARG B CA 232 ARG B CA 1 ATOM 3108 C C . ARG B 2 232 ? 13.685 -16.131 -4.069 1.00 93.10 ? 232 ARG B C 232 ARG B C 1 ATOM 3109 O O . ARG B 2 232 ? 13.595 -17.259 -3.581 1.00 93.10 ? 232 ARG B O 232 ARG B O 1 ATOM 3110 C CB . ARG B 2 232 ? 13.171 -15.815 -6.499 1.00 93.10 ? 232 ARG B CB 232 ARG B CB 1 ATOM 3111 C CG . ARG B 2 232 ? 13.338 -17.268 -6.916 1.00 93.10 ? 232 ARG B CG 232 ARG B CG 1 ATOM 3112 C CD . ARG B 2 232 ? 13.929 -17.389 -8.313 1.00 93.10 ? 232 ARG B CD 232 ARG B CD 1 ATOM 3113 N NE . ARG B 2 232 ? 13.125 -16.676 -9.302 1.00 93.10 ? 232 ARG B NE 232 ARG B NE 1 ATOM 3114 C CZ . ARG B 2 232 ? 13.522 -15.591 -9.962 1.00 93.10 ? 232 ARG B CZ 232 ARG B CZ 1 ATOM 3115 N NH1 . ARG B 2 232 ? 14.726 -15.071 -9.750 1.00 93.10 ? 232 ARG B NH1 232 ARG B NH1 1 ATOM 3116 N NH2 . ARG B 2 232 ? 12.710 -15.021 -10.840 1.00 93.10 ? 232 ARG B NH2 232 ARG B NH2 1 ATOM 3117 N N . SER B 2 233 ? 14.601 -15.313 -3.710 1.00 92.86 ? 233 SER B N 233 SER B N 1 ATOM 3118 C CA . SER B 2 233 ? 15.680 -15.679 -2.799 1.00 92.86 ? 233 SER B CA 233 SER B CA 1 ATOM 3119 C C . SER B 2 233 ? 15.152 -15.938 -1.392 1.00 92.86 ? 233 SER B C 233 SER B C 1 ATOM 3120 O O . SER B 2 233 ? 15.686 -16.781 -0.668 1.00 92.86 ? 233 SER B O 233 SER B O 1 ATOM 3121 C CB . SER B 2 233 ? 16.744 -14.581 -2.759 1.00 92.86 ? 233 SER B CB 233 SER B CB 1 ATOM 3122 O OG . SER B 2 233 ? 17.362 -14.433 -4.026 1.00 92.86 ? 233 SER B OG 233 SER B OG 1 ATOM 3123 N N . TYR B 2 234 ? 14.110 -15.315 -1.015 1.00 93.49 ? 234 TYR B N 234 TYR B N 1 ATOM 3124 C CA . TYR B 2 234 ? 13.542 -15.450 0.322 1.00 93.49 ? 234 TYR B CA 234 TYR B CA 1 ATOM 3125 C C . TYR B 2 234 ? 12.301 -16.334 0.301 1.00 93.49 ? 234 TYR B C 234 TYR B C 1 ATOM 3126 O O . TYR B 2 234 ? 11.547 -16.380 1.275 1.00 93.49 ? 234 TYR B O 234 TYR B O 1 ATOM 3127 C CB . TYR B 2 234 ? 13.193 -14.074 0.899 1.00 93.49 ? 234 TYR B CB 234 TYR B CB 1 ATOM 3128 C CG . TYR B 2 234 ? 14.391 -13.307 1.405 1.00 93.49 ? 234 TYR B CG 234 TYR B CG 1 ATOM 3129 C CD1 . TYR B 2 234 ? 14.831 -13.452 2.719 1.00 93.49 ? 234 TYR B CD1 234 TYR B CD1 1 ATOM 3130 C CD2 . TYR B 2 234 ? 15.083 -12.435 0.571 1.00 93.49 ? 234 TYR B CD2 234 TYR B CD2 1 ATOM 3131 C CE1 . TYR B 2 234 ? 15.933 -12.745 3.190 1.00 93.49 ? 234 TYR B CE1 234 TYR B CE1 1 ATOM 3132 C CE2 . TYR B 2 234 ? 16.186 -11.723 1.032 1.00 93.49 ? 234 TYR B CE2 234 TYR B CE2 1 ATOM 3133 C CZ . TYR B 2 234 ? 16.603 -11.885 2.340 1.00 93.49 ? 234 TYR B CZ 234 TYR B CZ 1 ATOM 3134 O OH . TYR B 2 234 ? 17.694 -11.183 2.801 1.00 93.49 ? 234 TYR B OH 234 TYR B OH 1 ATOM 3135 N N . ASN B 2 235 ? 12.082 -17.023 -0.801 1.00 92.86 ? 235 ASN B N 235 ASN B N 1 ATOM 3136 C CA . ASN B 2 235 ? 10.926 -17.898 -0.966 1.00 92.86 ? 235 ASN B CA 235 ASN B CA 1 ATOM 3137 C C . ASN B 2 235 ? 9.619 -17.158 -0.698 1.00 92.86 ? 235 ASN B C 235 ASN B C 1 ATOM 3138 O O . ASN B 2 235 ? 8.757 -17.655 0.029 1.00 92.86 ? 235 ASN B O 235 ASN B O 1 ATOM 3139 C CB . ASN B 2 235 ? 11.042 -19.119 -0.052 1.00 92.86 ? 235 ASN B CB 235 ASN B CB 1 ATOM 3140 C CG . ASN B 2 235 ? 10.049 -20.210 -0.404 1.00 92.86 ? 235 ASN B CG 235 ASN B CG 1 ATOM 3141 O OD1 . ASN B 2 235 ? 9.652 -20.353 -1.563 1.00 92.86 ? 235 ASN B OD1 235 ASN B OD1 1 ATOM 3142 N ND2 . ASN B 2 235 ? 9.643 -20.986 0.593 1.00 92.86 ? 235 ASN B ND2 235 ASN B ND2 1 ATOM 3143 N N . CYS B 2 236 ? 9.529 -16.003 -1.280 1.00 95.13 ? 236 CYS B N 236 CYS B N 1 ATOM 3144 C CA . CYS B 2 236 ? 8.350 -15.152 -1.164 1.00 95.13 ? 236 CYS B CA 236 CYS B CA 1 ATOM 3145 C C . CYS B 2 236 ? 7.777 -14.824 -2.537 1.00 95.13 ? 236 CYS B C 236 CYS B C 1 ATOM 3146 O O . CYS B 2 236 ? 8.451 -14.998 -3.554 1.00 95.13 ? 236 CYS B O 236 CYS B O 1 ATOM 3147 C CB . CYS B 2 236 ? 8.692 -13.860 -0.422 1.00 95.13 ? 236 CYS B CB 236 CYS B CB 1 ATOM 3148 S SG . CYS B 2 236 ? 9.159 -14.113 1.304 1.00 95.13 ? 236 CYS B SG 236 CYS B SG 1 ATOM 3149 N N . GLY B 2 237 ? 6.510 -14.501 -2.543 1.00 94.77 ? 237 GLY B N 237 GLY B N 1 ATOM 3150 C CA . GLY B 2 237 ? 5.866 -13.954 -3.726 1.00 94.77 ? 237 GLY B CA 237 GLY B CA 1 ATOM 3151 C C . GLY B 2 237 ? 5.484 -12.494 -3.576 1.00 94.77 ? 237 GLY B C 237 GLY B C 1 ATOM 3152 O O . GLY B 2 237 ? 5.121 -12.050 -2.485 1.00 94.77 ? 237 GLY B O 237 GLY B O 1 ATOM 3153 N N . VAL B 2 238 ? 5.635 -11.759 -4.707 1.00 97.10 ? 238 VAL B N 238 VAL B N 1 ATOM 3154 C CA . VAL B 2 238 ? 5.186 -10.371 -4.706 1.00 97.10 ? 238 VAL B CA 238 VAL B CA 1 ATOM 3155 C C . VAL B 2 238 ? 3.664 -10.319 -4.812 1.00 97.10 ? 238 VAL B C 238 VAL B C 1 ATOM 3156 O O . VAL B 2 238 ? 3.079 -10.908 -5.725 1.00 97.10 ? 238 VAL B O 238 VAL B O 1 ATOM 3157 C CB . VAL B 2 238 ? 5.828 -9.566 -5.858 1.00 97.10 ? 238 VAL B CB 238 VAL B CB 1 ATOM 3158 C CG1 . VAL B 2 238 ? 5.437 -8.092 -5.770 1.00 97.10 ? 238 VAL B CG1 238 VAL B CG1 1 ATOM 3159 C CG2 . VAL B 2 238 ? 7.348 -9.720 -5.834 1.00 97.10 ? 238 VAL B CG2 238 VAL B CG2 1 ATOM 3160 N N . VAL B 2 239 ? 3.038 -9.697 -3.893 1.00 96.73 ? 239 VAL B N 239 VAL B N 1 ATOM 3161 C CA . VAL B 2 239 ? 1.582 -9.636 -3.819 1.00 96.73 ? 239 VAL B CA 239 VAL B CA 1 ATOM 3162 C C . VAL B 2 239 ? 1.051 -8.676 -4.881 1.00 96.73 ? 239 VAL B C 239 VAL B C 1 ATOM 3163 O O . VAL B 2 239 ? 1.603 -7.590 -5.077 1.00 96.73 ? 239 VAL B O 239 VAL B O 1 ATOM 3164 C CB . VAL B 2 239 ? 1.103 -9.199 -2.417 1.00 96.73 ? 239 VAL B CB 239 VAL B CB 1 ATOM 3165 C CG1 . VAL B 2 239 ? -0.421 -9.104 -2.373 1.00 96.73 ? 239 VAL B CG1 239 VAL B CG1 1 ATOM 3166 C CG2 . VAL B 2 239 ? 1.611 -10.170 -1.353 1.00 96.73 ? 239 VAL B CG2 239 VAL B CG2 1 ATOM 3167 N N . PRO B 2 240 ? -0.021 -9.122 -5.581 1.00 94.16 ? 240 PRO B N 240 PRO B N 1 ATOM 3168 C CA . PRO B 2 240 ? -0.654 -8.191 -6.518 1.00 94.16 ? 240 PRO B CA 240 PRO B CA 1 ATOM 3169 C C . PRO B 2 240 ? -1.083 -6.885 -5.852 1.00 94.16 ? 240 PRO B C 240 PRO B C 1 ATOM 3170 O O . PRO B 2 240 ? -1.578 -6.897 -4.722 1.00 94.16 ? 240 PRO B O 240 PRO B O 1 ATOM 3171 C CB . PRO B 2 240 ? -1.870 -8.971 -7.023 1.00 94.16 ? 240 PRO B CB 240 PRO B CB 1 ATOM 3172 C CG . PRO B 2 240 ? -1.510 -10.408 -6.829 1.00 94.16 ? 240 PRO B CG 240 PRO B CG 1 ATOM 3173 C CD . PRO B 2 240 ? -0.679 -10.528 -5.584 1.00 94.16 ? 240 PRO B CD 240 PRO B CD 1 ATOM 3174 N N . GLY B 2 241 ? -0.787 -5.782 -6.453 1.00 89.76 ? 241 GLY B N 241 GLY B N 1 ATOM 3175 C CA . GLY B 2 241 ? -1.026 -4.463 -5.889 1.00 89.76 ? 241 GLY B CA 241 GLY B CA 1 ATOM 3176 C C . GLY B 2 241 ? 0.250 -3.697 -5.601 1.00 89.76 ? 241 GLY B C 241 GLY B C 1 ATOM 3177 O O . GLY B 2 241 ? 0.217 -2.485 -5.380 1.00 89.76 ? 241 GLY B O 241 GLY B O 1 ATOM 3178 N N . SER B 2 242 ? 1.381 -4.509 -5.576 1.00 95.54 ? 242 SER B N 242 SER B N 1 ATOM 3179 C CA . SER B 2 242 ? 2.685 -3.868 -5.451 1.00 95.54 ? 242 SER B CA 242 SER B CA 1 ATOM 3180 C C . SER B 2 242 ? 2.996 -3.004 -6.669 1.00 95.54 ? 242 SER B C 242 SER B C 1 ATOM 3181 O O . SER B 2 242 ? 2.687 -3.384 -7.801 1.00 95.54 ? 242 SER B O 242 SER B O 1 ATOM 3182 C CB . SER B 2 242 ? 3.783 -4.916 -5.266 1.00 95.54 ? 242 SER B CB 242 SER B CB 1 ATOM 3183 O OG . SER B 2 242 ? 3.573 -5.660 -4.078 1.00 95.54 ? 242 SER B OG 242 SER B OG 1 ATOM 3184 N N . ARG B 2 243 ? 3.625 -1.860 -6.371 1.00 94.06 ? 243 ARG B N 243 ARG B N 1 ATOM 3185 C CA . ARG B 2 243 ? 3.877 -0.982 -7.509 1.00 94.06 ? 243 ARG B CA 243 ARG B CA 1 ATOM 3186 C C . ARG B 2 243 ? 4.988 0.014 -7.197 1.00 94.06 ? 243 ARG B C 243 ARG B C 1 ATOM 3187 O O . ARG B 2 243 ? 5.222 0.347 -6.033 1.00 94.06 ? 243 ARG B O 243 ARG B O 1 ATOM 3188 C CB . ARG B 2 243 ? 2.601 -0.236 -7.906 1.00 94.06 ? 243 ARG B CB 243 ARG B CB 1 ATOM 3189 C CG . ARG B 2 243 ? 2.051 0.668 -6.814 1.00 94.06 ? 243 ARG B CG 243 ARG B CG 1 ATOM 3190 C CD . ARG B 2 243 ? 0.705 1.264 -7.200 1.00 94.06 ? 243 ARG B CD 243 ARG B CD 1 ATOM 3191 N NE . ARG B 2 243 ? 0.162 2.104 -6.136 1.00 94.06 ? 243 ARG B NE 243 ARG B NE 1 ATOM 3192 C CZ . ARG B 2 243 ? -1.013 2.725 -6.185 1.00 94.06 ? 243 ARG B CZ 243 ARG B CZ 1 ATOM 3193 N NH1 . ARG B 2 243 ? -1.796 2.612 -7.252 1.00 94.06 ? 243 ARG B NH1 243 ARG B NH1 1 ATOM 3194 N NH2 . ARG B 2 243 ? -1.410 3.464 -5.159 1.00 94.06 ? 243 ARG B NH2 243 ARG B NH2 1 ATOM 3195 N N . VAL B 2 244 ? 5.739 0.339 -8.220 1.00 94.95 ? 244 VAL B N 244 VAL B N 1 ATOM 3196 C CA . VAL B 2 244 ? 6.657 1.470 -8.286 1.00 94.95 ? 244 VAL B CA 244 VAL B CA 1 ATOM 3197 C C . VAL B 2 244 ? 6.219 2.427 -9.393 1.00 94.95 ? 244 VAL B C 244 VAL B C 1 ATOM 3198 O O . VAL B 2 244 ? 6.303 2.096 -10.577 1.00 94.95 ? 244 VAL B O 244 VAL B O 1 ATOM 3199 C CB . VAL B 2 244 ? 8.112 1.008 -8.526 1.00 94.95 ? 244 VAL B CB 244 VAL B CB 1 ATOM 3200 C CG1 . VAL B 2 244 ? 9.063 2.203 -8.540 1.00 94.95 ? 244 VAL B CG1 244 VAL B CG1 1 ATOM 3201 C CG2 . VAL B 2 244 ? 8.532 -0.002 -7.460 1.00 94.95 ? 244 VAL B CG2 244 VAL B CG2 1 ATOM 3202 N N . ARG B 2 245 ? 5.797 3.551 -8.910 1.00 90.46 ? 245 ARG B N 245 ARG B N 1 ATOM 3203 C CA . ARG B 2 245 ? 5.190 4.395 -9.934 1.00 90.46 ? 245 ARG B CA 245 ARG B CA 1 ATOM 3204 C C . ARG B 2 245 ? 5.505 5.867 -9.689 1.00 90.46 ? 245 ARG B C 245 ARG B C 1 ATOM 3205 O O . ARG B 2 245 ? 5.758 6.272 -8.553 1.00 90.46 ? 245 ARG B O 245 ARG B O 1 ATOM 3206 C CB . ARG B 2 245 ? 3.675 4.184 -9.977 1.00 90.46 ? 245 ARG B CB 245 ARG B CB 1 ATOM 3207 C CG . ARG B 2 245 ? 2.936 4.786 -8.792 1.00 90.46 ? 245 ARG B CG 245 ARG B CG 1 ATOM 3208 C CD . ARG B 2 245 ? 1.426 4.670 -8.952 1.00 90.46 ? 245 ARG B CD 245 ARG B CD 1 ATOM 3209 N NE . ARG B 2 245 ? 0.716 5.472 -7.959 1.00 90.46 ? 245 ARG B NE 245 ARG B NE 1 ATOM 3210 C CZ . ARG B 2 245 ? -0.352 6.222 -8.215 1.00 90.46 ? 245 ARG B CZ 245 ARG B CZ 1 ATOM 3211 N NH1 . ARG B 2 245 ? -0.857 6.287 -9.441 1.00 90.46 ? 245 ARG B NH1 245 ARG B NH1 1 ATOM 3212 N NH2 . ARG B 2 245 ? -0.921 6.912 -7.237 1.00 90.46 ? 245 ARG B NH2 245 ARG B NH2 1 ATOM 3213 N N . ARG B 2 246 ? 5.358 6.588 -10.740 1.00 90.15 ? 246 ARG B N 246 ARG B N 1 ATOM 3214 C CA . ARG B 2 246 ? 5.539 8.036 -10.704 1.00 90.15 ? 246 ARG B CA 246 ARG B CA 1 ATOM 3215 C C . ARG B 2 246 ? 4.276 8.733 -10.209 1.00 90.15 ? 246 ARG B C 246 ARG B C 1 ATOM 3216 O O . ARG B 2 246 ? 3.169 8.402 -10.639 1.00 90.15 ? 246 ARG B O 246 ARG B O 1 ATOM 3217 C CB . ARG B 2 246 ? 5.922 8.565 -12.088 1.00 90.15 ? 246 ARG B CB 246 ARG B CB 1 ATOM 3218 C CG . ARG B 2 246 ? 6.205 10.059 -12.119 1.00 90.15 ? 246 ARG B CG 246 ARG B CG 1 ATOM 3219 C CD . ARG B 2 246 ? 6.475 10.552 -13.534 1.00 90.15 ? 246 ARG B CD 246 ARG B CD 1 ATOM 3220 N NE . ARG B 2 246 ? 5.248 10.627 -14.322 1.00 90.15 ? 246 ARG B NE 246 ARG B NE 1 ATOM 3221 C CZ . ARG B 2 246 ? 5.194 10.946 -15.612 1.00 90.15 ? 246 ARG B CZ 246 ARG B CZ 1 ATOM 3222 N NH1 . ARG B 2 246 ? 6.302 11.228 -16.288 1.00 90.15 ? 246 ARG B NH1 246 ARG B NH1 1 ATOM 3223 N NH2 . ARG B 2 246 ? 4.023 10.984 -16.231 1.00 90.15 ? 246 ARG B NH2 246 ARG B NH2 1 ATOM 3224 N N . ILE B 2 247 ? 4.534 9.688 -9.202 1.00 85.54 ? 247 ILE B N 247 ILE B N 1 ATOM 3225 C CA . ILE B 2 247 ? 3.421 10.437 -8.628 1.00 85.54 ? 247 ILE B CA 247 ILE B CA 1 ATOM 3226 C C . ILE B 2 247 ? 3.309 11.798 -9.312 1.00 85.54 ? 247 ILE B C 247 ILE B C 1 ATOM 3227 O O . ILE B 2 247 ? 4.292 12.537 -9.403 1.00 85.54 ? 247 ILE B O 247 ILE B O 1 ATOM 3228 C CB . ILE B 2 247 ? 3.587 10.616 -7.103 1.00 85.54 ? 247 ILE B CB 247 ILE B CB 1 ATOM 3229 C CG1 . ILE B 2 247 ? 3.645 9.251 -6.408 1.00 85.54 ? 247 ILE B CG1 247 ILE B CG1 1 ATOM 3230 C CG2 . ILE B 2 247 ? 2.453 11.473 -6.533 1.00 85.54 ? 247 ILE B CG2 247 ILE B CG2 1 ATOM 3231 C CD1 . ILE B 2 247 ? 4.013 9.322 -4.932 1.00 85.54 ? 247 ILE B CD1 247 ILE B CD1 1 ATOM 3232 N N . ARG B 2 248 ? 2.132 12.087 -9.828 1.00 78.82 ? 248 ARG B N 248 ARG B N 1 ATOM 3233 C CA . ARG B 2 248 ? 1.823 13.413 -10.354 1.00 78.82 ? 248 ARG B CA 248 ARG B CA 1 ATOM 3234 C C . ARG B 2 248 ? 0.825 14.139 -9.458 1.00 78.82 ? 248 ARG B C 248 ARG B C 1 ATOM 3235 O O . ARG B 2 248 ? 0.066 13.504 -8.723 1.00 78.82 ? 248 ARG B O 248 ARG B O 1 ATOM 3236 C CB . ARG B 2 248 ? 1.270 13.311 -11.778 1.00 78.82 ? 248 ARG B CB 248 ARG B CB 1 ATOM 3237 C CG . ARG B 2 248 ? 2.277 12.796 -12.794 1.00 78.82 ? 248 ARG B CG 248 ARG B CG 1 ATOM 3238 C CD . ARG B 2 248 ? 1.694 12.765 -14.200 1.00 78.82 ? 248 ARG B CD 248 ARG B CD 1 ATOM 3239 N NE . ARG B 2 248 ? 2.673 12.303 -15.179 1.00 78.82 ? 248 ARG B NE 248 ARG B NE 1 ATOM 3240 C CZ . ARG B 2 248 ? 2.425 12.125 -16.474 1.00 78.82 ? 248 ARG B CZ 248 ARG B CZ 1 ATOM 3241 N NH1 . ARG B 2 248 ? 1.217 12.366 -16.972 1.00 78.82 ? 248 ARG B NH1 248 ARG B NH1 1 ATOM 3242 N NH2 . ARG B 2 248 ? 3.390 11.701 -17.277 1.00 78.82 ? 248 ARG B NH2 248 ARG B NH2 1 ATOM 3243 N N . ARG B 2 249 ? 0.901 15.397 -9.427 1.00 71.23 ? 249 ARG B N 249 ARG B N 1 ATOM 3244 C CA . ARG B 2 249 ? -0.077 16.168 -8.666 1.00 71.23 ? 249 ARG B CA 249 ARG B CA 1 ATOM 3245 C C . ARG B 2 249 ? -1.498 15.844 -9.113 1.00 71.23 ? 249 ARG B C 249 ARG B C 1 ATOM 3246 O O . ARG B 2 249 ? -1.751 15.649 -10.304 1.00 71.23 ? 249 ARG B O 249 ARG B O 1 ATOM 3247 C CB . ARG B 2 249 ? 0.189 17.668 -8.814 1.00 71.23 ? 249 ARG B CB 249 ARG B CB 1 ATOM 3248 C CG . ARG B 2 249 ? -0.708 18.541 -7.950 1.00 71.23 ? 249 ARG B CG 249 ARG B CG 1 ATOM 3249 C CD . ARG B 2 249 ? -0.393 20.020 -8.124 1.00 71.23 ? 249 ARG B CD 249 ARG B CD 1 ATOM 3250 N NE . ARG B 2 249 ? -1.313 20.860 -7.363 1.00 71.23 ? 249 ARG B NE 249 ARG B NE 1 ATOM 3251 C CZ . ARG B 2 249 ? -1.752 22.053 -7.756 1.00 71.23 ? 249 ARG B CZ 249 ARG B CZ 1 ATOM 3252 N NH1 . ARG B 2 249 ? -1.360 22.571 -8.914 1.00 71.23 ? 249 ARG B NH1 249 ARG B NH1 1 ATOM 3253 N NH2 . ARG B 2 249 ? -2.588 22.733 -6.985 1.00 71.23 ? 249 ARG B NH2 249 ARG B NH2 1 ATOM 3254 N N . PHE B 2 250 ? -2.424 15.678 -8.162 1.00 60.67 ? 250 PHE B N 250 PHE B N 1 ATOM 3255 C CA . PHE B 2 250 ? -3.872 15.552 -8.278 1.00 60.67 ? 250 PHE B CA 250 PHE B CA 1 ATOM 3256 C C . PHE B 2 250 ? -4.278 14.091 -8.429 1.00 60.67 ? 250 PHE B C 250 PHE B C 1 ATOM 3257 O O . PHE B 2 250 ? -5.380 13.704 -8.035 1.00 60.67 ? 250 PHE B O 250 PHE B O 1 ATOM 3258 C CB . PHE B 2 250 ? -4.390 16.366 -9.468 1.00 60.67 ? 250 PHE B CB 250 PHE B CB 1 ATOM 3259 C CG . PHE B 2 250 ? -4.436 17.849 -9.215 1.00 60.67 ? 250 PHE B CG 250 PHE B CG 1 ATOM 3260 C CD1 . PHE B 2 250 ? -5.352 18.387 -8.319 1.00 60.67 ? 250 PHE B CD1 250 PHE B CD1 1 ATOM 3261 C CD2 . PHE B 2 250 ? -3.563 18.705 -9.873 1.00 60.67 ? 250 PHE B CD2 250 PHE B CD2 1 ATOM 3262 C CE1 . PHE B 2 250 ? -5.397 19.759 -8.083 1.00 60.67 ? 250 PHE B CE1 250 PHE B CE1 1 ATOM 3263 C CE2 . PHE B 2 250 ? -3.602 20.077 -9.642 1.00 60.67 ? 250 PHE B CE2 250 PHE B CE2 1 ATOM 3264 C CZ . PHE B 2 250 ? -4.520 20.602 -8.748 1.00 60.67 ? 250 PHE B CZ 250 PHE B CZ 1 ATOM 3265 N N . LEU B 2 251 ? -3.211 13.239 -8.912 1.00 57.72 ? 251 LEU B N 251 LEU B N 1 ATOM 3266 C CA . LEU B 2 251 ? -3.570 11.839 -9.110 1.00 57.72 ? 251 LEU B CA 251 LEU B CA 1 ATOM 3267 C C . LEU B 2 251 ? -3.163 10.997 -7.905 1.00 57.72 ? 251 LEU B C 251 LEU B C 1 ATOM 3268 O O . LEU B 2 251 ? -3.629 9.866 -7.747 1.00 57.72 ? 251 LEU B O 251 LEU B O 1 ATOM 3269 C CB . LEU B 2 251 ? -2.910 11.290 -10.378 1.00 57.72 ? 251 LEU B CB 251 LEU B CB 1 ATOM 3270 C CG . LEU B 2 251 ? -3.435 11.836 -11.706 1.00 57.72 ? 251 LEU B CG 251 LEU B CG 1 ATOM 3271 C CD1 . LEU B 2 251 ? -2.546 11.376 -12.857 1.00 57.72 ? 251 LEU B CD1 251 LEU B CD1 1 ATOM 3272 C CD2 . LEU B 2 251 ? -4.878 11.397 -11.932 1.00 57.72 ? 251 LEU B CD2 251 LEU B CD2 1 ATOM 3273 N N . ALA B 2 252 ? -2.322 11.581 -7.013 1.00 50.33 ? 252 ALA B N 252 ALA B N 1 ATOM 3274 C CA . ALA B 2 252 ? -1.798 10.845 -5.865 1.00 50.33 ? 252 ALA B CA 252 ALA B CA 1 ATOM 3275 C C . ALA B 2 252 ? -2.859 10.696 -4.779 1.00 50.33 ? 252 ALA B C 252 ALA B C 1 ATOM 3276 O O . ALA B 2 252 ? -3.484 11.679 -4.373 1.00 50.33 ? 252 ALA B O 252 ALA B O 1 ATOM 3277 C CB . ALA B 2 252 ? -0.562 11.544 -5.305 1.00 50.33 ? 252 ALA B CB 252 ALA B CB 1 ATOM 3278 N N . GLY B 2 253 ? -3.778 9.808 -4.795 1.00 50.10 ? 253 GLY B N 253 GLY B N 1 ATOM 3279 C CA . GLY B 2 253 ? -4.631 9.588 -3.638 1.00 50.10 ? 253 GLY B CA 253 GLY B CA 1 ATOM 3280 C C . GLY B 2 253 ? -6.109 9.739 -3.949 1.00 50.10 ? 253 GLY B C 253 GLY B C 1 ATOM 3281 O O . GLY B 2 253 ? -6.960 9.383 -3.131 1.00 50.10 ? 253 GLY B O 253 GLY B O 1 ATOM 3282 N N . GLN B 2 254 ? -6.503 10.281 -5.165 1.00 57.74 ? 254 GLN B N 254 GLN B N 1 ATOM 3283 C CA . GLN B 2 254 ? -7.799 10.820 -5.561 1.00 57.74 ? 254 GLN B CA 254 GLN B CA 1 ATOM 3284 C C . GLN B 2 254 ? -8.660 9.750 -6.226 1.00 57.74 ? 254 GLN B C 254 GLN B C 1 ATOM 3285 O O . GLN B 2 254 ? -9.844 9.613 -5.909 1.00 57.74 ? 254 GLN B O 254 GLN B O 1 ATOM 3286 C CB . GLN B 2 254 ? -7.620 12.011 -6.504 1.00 57.74 ? 254 GLN B CB 254 GLN B CB 1 ATOM 3287 C CG . GLN B 2 254 ? -6.968 13.221 -5.849 1.00 57.74 ? 254 GLN B CG 254 GLN B CG 1 ATOM 3288 C CD . GLN B 2 254 ? -6.777 14.378 -6.812 1.00 57.74 ? 254 GLN B CD 254 GLN B CD 1 ATOM 3289 O OE1 . GLN B 2 254 ? -7.280 14.353 -7.940 1.00 57.74 ? 254 GLN B OE1 254 GLN B OE1 1 ATOM 3290 N NE2 . GLN B 2 254 ? -6.049 15.400 -6.375 1.00 57.74 ? 254 GLN B NE2 254 GLN B NE2 1 ATOM 3291 N N . ASN B 2 255 ? -7.979 8.536 -6.876 1.00 50.05 ? 255 ASN B N 255 ASN B N 1 ATOM 3292 C CA . ASN B 2 255 ? -8.756 7.730 -7.812 1.00 50.05 ? 255 ASN B CA 255 ASN B CA 1 ATOM 3293 C C . ASN B 2 255 ? -7.874 6.737 -8.564 1.00 50.05 ? 255 ASN B C 255 ASN B C 1 ATOM 3294 O O . ASN B 2 255 ? -7.934 6.653 -9.792 1.00 50.05 ? 255 ASN B O 255 ASN B O 1 ATOM 3295 C CB . ASN B 2 255 ? -9.506 8.628 -8.799 1.00 50.05 ? 255 ASN B CB 255 ASN B CB 1 ATOM 3296 C CG . ASN B 2 255 ? -10.734 9.272 -8.186 1.00 50.05 ? 255 ASN B CG 255 ASN B CG 1 ATOM 3297 O OD1 . ASN B 2 255 ? -11.255 8.801 -7.171 1.00 50.05 ? 255 ASN B OD1 255 ASN B OD1 1 ATOM 3298 N ND2 . ASN B 2 255 ? -11.204 10.353 -8.796 1.00 50.05 ? 255 ASN B ND2 255 ASN B ND2 1 ATOM 3299 N N . GLU B 2 256 ? -6.701 6.474 -7.939 1.00 54.44 ? 256 GLU B N 256 GLU B N 1 ATOM 3300 C CA . GLU B 2 256 ? -5.937 5.484 -8.692 1.00 54.44 ? 256 GLU B CA 256 GLU B CA 1 ATOM 3301 C C . GLU B 2 256 ? -6.787 4.257 -9.010 1.00 54.44 ? 256 GLU B C 256 GLU B C 1 ATOM 3302 O O . GLU B 2 256 ? -7.409 3.678 -8.116 1.00 54.44 ? 256 GLU B O 256 GLU B O 1 ATOM 3303 C CB . GLU B 2 256 ? -4.683 5.069 -7.918 1.00 54.44 ? 256 GLU B CB 256 GLU B CB 1 ATOM 3304 C CG . GLU B 2 256 ? -3.576 6.113 -7.938 1.00 54.44 ? 256 GLU B CG 256 GLU B CG 1 ATOM 3305 C CD . GLU B 2 256 ? -2.325 5.674 -7.192 1.00 54.44 ? 256 GLU B CD 256 GLU B CD 1 ATOM 3306 O OE1 . GLU B 2 256 ? -1.351 6.458 -7.127 1.00 54.44 ? 256 GLU B OE1 256 GLU B OE1 1 ATOM 3307 O OE2 . GLU B 2 256 ? -2.319 4.537 -6.670 1.00 54.44 ? 256 GLU B OE2 256 GLU B OE2 1 ATOM 3308 N N . GLY B 2 257 ? -7.408 4.275 -10.155 1.00 49.03 ? 257 GLY B N 257 GLY B N 1 ATOM 3309 C CA . GLY B 2 257 ? -8.222 3.176 -10.649 1.00 49.03 ? 257 GLY B CA 257 GLY B CA 1 ATOM 3310 C C . GLY B 2 257 ? -9.537 3.633 -11.253 1.00 49.03 ? 257 GLY B C 257 GLY B C 1 ATOM 3311 O O . GLY B 2 257 ? -10.157 2.902 -12.028 1.00 49.03 ? 257 GLY B O 257 GLY B O 1 ATOM 3312 N N . ILE B 2 258 ? -9.877 4.920 -10.813 1.00 55.70 ? 258 ILE B N 258 ILE B N 1 ATOM 3313 C CA . ILE B 2 258 ? -11.135 5.434 -11.346 1.00 55.70 ? 258 ILE B CA 258 ILE B CA 1 ATOM 3314 C C . ILE B 2 258 ? -10.868 6.234 -12.618 1.00 55.70 ? 258 ILE B C 258 ILE B C 1 ATOM 3315 O O . ILE B 2 258 ? -11.569 6.072 -13.620 1.00 55.70 ? 258 ILE B O 258 ILE B O 1 ATOM 3316 C CB . ILE B 2 258 ? -11.873 6.308 -10.307 1.00 55.70 ? 258 ILE B CB 258 ILE B CB 1 ATOM 3317 C CG1 . ILE B 2 258 ? -12.241 5.476 -9.073 1.00 55.70 ? 258 ILE B CG1 258 ILE B CG1 1 ATOM 3318 C CG2 . ILE B 2 258 ? -13.118 6.948 -10.928 1.00 55.70 ? 258 ILE B CG2 258 ILE B CG2 1 ATOM 3319 C CD1 . ILE B 2 258 ? -12.786 6.298 -7.913 1.00 55.70 ? 258 ILE B CD1 258 ILE B CD1 1 ATOM 3320 N N . VAL B 2 259 ? -9.675 6.994 -12.551 1.00 59.62 ? 259 VAL B N 259 VAL B N 1 ATOM 3321 C CA . VAL B 2 259 ? -9.285 7.795 -13.706 1.00 59.62 ? 259 VAL B CA 259 VAL B CA 1 ATOM 3322 C C . VAL B 2 259 ? -7.990 7.246 -14.302 1.00 59.62 ? 259 VAL B C 259 VAL B C 1 ATOM 3323 O O . VAL B 2 259 ? -7.018 7.012 -13.581 1.00 59.62 ? 259 VAL B O 259 VAL B O 1 ATOM 3324 C CB . VAL B 2 259 ? -9.110 9.284 -13.332 1.00 59.62 ? 259 VAL B CB 259 VAL B CB 1 ATOM 3325 C CG1 . VAL B 2 259 ? -8.688 10.101 -14.551 1.00 59.62 ? 259 VAL B CG1 259 VAL B CG1 1 ATOM 3326 C CG2 . VAL B 2 259 ? -10.401 9.838 -12.733 1.00 59.62 ? 259 VAL B CG2 259 VAL B CG2 1 ATOM 3327 N N . ALA B 2 260 ? -8.026 6.772 -15.527 1.00 60.67 ? 260 ALA B N 260 ALA B N 1 ATOM 3328 C CA . ALA B 2 260 ? -6.861 6.259 -16.242 1.00 60.67 ? 260 ALA B CA 260 ALA B CA 1 ATOM 3329 C C . ALA B 2 260 ? -5.924 7.394 -16.648 1.00 60.67 ? 260 ALA B C 260 ALA B C 1 ATOM 3330 O O . ALA B 2 260 ? -6.361 8.392 -17.225 1.00 60.67 ? 260 ALA B O 260 ALA B O 1 ATOM 3331 C CB . ALA B 2 260 ? -7.297 5.468 -17.473 1.00 60.67 ? 260 ALA B CB 260 ALA B CB 1 ATOM 3332 N N . GLU B 2 261 ? -4.722 7.392 -16.119 1.00 68.52 ? 261 GLU B N 261 GLU B N 1 ATOM 3333 C CA . GLU B 2 261 ? -3.683 8.367 -16.434 1.00 68.52 ? 261 GLU B CA 261 GLU B CA 1 ATOM 3334 C C . GLU B 2 261 ? -3.168 8.185 -17.859 1.00 68.52 ? 261 GLU B C 261 GLU B C 1 ATOM 3335 O O . GLU B 2 261 ? -2.938 7.057 -18.301 1.00 68.52 ? 261 GLU B O 261 GLU B O 1 ATOM 3336 C CB . GLU B 2 261 ? -2.525 8.260 -15.438 1.00 68.52 ? 261 GLU B CB 261 GLU B CB 1 ATOM 3337 C CG . GLU B 2 261 ? -2.912 8.596 -14.006 1.00 68.52 ? 261 GLU B CG 261 GLU B CG 1 ATOM 3338 C CD . GLU B 2 261 ? -1.757 8.464 -13.025 1.00 68.52 ? 261 GLU B CD 261 GLU B CD 1 ATOM 3339 O OE1 . GLU B 2 261 ? -1.948 8.747 -11.821 1.00 68.52 ? 261 GLU B OE1 261 GLU B OE1 1 ATOM 3340 O OE2 . GLU B 2 261 ? -0.652 8.075 -13.466 1.00 68.52 ? 261 GLU B OE2 261 GLU B OE2 1 ATOM 3341 N N . ARG B 2 262 ? -3.111 9.392 -18.551 1.00 70.62 ? 262 ARG B N 262 ARG B N 1 ATOM 3342 C CA . ARG B 2 262 ? -2.453 9.422 -19.853 1.00 70.62 ? 262 ARG B CA 262 ARG B CA 1 ATOM 3343 C C . ARG B 2 262 ? -0.936 9.369 -19.701 1.00 70.62 ? 262 ARG B C 262 ARG B C 1 ATOM 3344 O O . ARG B 2 262 ? -0.370 10.041 -18.836 1.00 70.62 ? 262 ARG B O 262 ARG B O 1 ATOM 3345 C CB . ARG B 2 262 ? -2.858 10.675 -20.632 1.00 70.62 ? 262 ARG B CB 262 ARG B CB 1 ATOM 3346 C CG . ARG B 2 262 ? -4.283 10.637 -21.162 1.00 70.62 ? 262 ARG B CG 262 ARG B CG 1 ATOM 3347 C CD . ARG B 2 262 ? -4.582 11.827 -22.063 1.00 70.62 ? 262 ARG B CD 262 ARG B CD 1 ATOM 3348 N NE . ARG B 2 262 ? -5.944 11.779 -22.586 1.00 70.62 ? 262 ARG B NE 262 ARG B NE 1 ATOM 3349 C CZ . ARG B 2 262 ? -6.470 12.676 -23.414 1.00 70.62 ? 262 ARG B CZ 262 ARG B CZ 1 ATOM 3350 N NH1 . ARG B 2 262 ? -5.755 13.715 -23.832 1.00 70.62 ? 262 ARG B NH1 262 ARG B NH1 1 ATOM 3351 N NH2 . ARG B 2 262 ? -7.721 12.535 -23.828 1.00 70.62 ? 262 ARG B NH2 262 ARG B NH2 1 ATOM 3352 N N . GLU B 2 263 ? -0.286 8.181 -19.876 1.00 75.34 ? 263 GLU B N 263 GLU B N 1 ATOM 3353 C CA . GLU B 2 263 ? 1.156 7.963 -19.812 1.00 75.34 ? 263 GLU B CA 263 GLU B CA 1 ATOM 3354 C C . GLU B 2 263 ? 1.569 7.399 -18.455 1.00 75.34 ? 263 GLU B C 263 GLU B C 1 ATOM 3355 O O . GLU B 2 263 ? 2.258 8.068 -17.682 1.00 75.34 ? 263 GLU B O 263 GLU B O 1 ATOM 3356 C CB . GLU B 2 263 ? 1.910 9.265 -20.091 1.00 75.34 ? 263 GLU B CB 263 GLU B CB 1 ATOM 3357 C CG . GLU B 2 263 ? 3.385 9.066 -20.407 1.00 75.34 ? 263 GLU B CG 263 GLU B CG 1 ATOM 3358 C CD . GLU B 2 263 ? 4.109 10.363 -20.733 1.00 75.34 ? 263 GLU B CD 263 GLU B CD 1 ATOM 3359 O OE1 . GLU B 2 263 ? 5.338 10.328 -20.973 1.00 75.34 ? 263 GLU B OE1 263 GLU B OE1 1 ATOM 3360 O OE2 . GLU B 2 263 ? 3.443 11.422 -20.749 1.00 75.34 ? 263 GLU B OE2 263 GLU B OE2 1 ATOM 3361 N N . TYR B 2 264 ? 1.075 6.352 -18.185 1.00 82.59 ? 264 TYR B N 264 TYR B N 1 ATOM 3362 C CA . TYR B 2 264 ? 1.408 5.660 -16.944 1.00 82.59 ? 264 TYR B CA 264 TYR B CA 1 ATOM 3363 C C . TYR B 2 264 ? 2.866 5.217 -16.940 1.00 82.59 ? 264 TYR B C 264 TYR B C 1 ATOM 3364 O O . TYR B 2 264 ? 3.307 4.504 -17.844 1.00 82.59 ? 264 TYR B O 264 TYR B O 1 ATOM 3365 C CB . TYR B 2 264 ? 0.493 4.448 -16.743 1.00 82.59 ? 264 TYR B CB 264 TYR B CB 1 ATOM 3366 C CG . TYR B 2 264 ? 0.708 3.737 -15.429 1.00 82.59 ? 264 TYR B CG 264 TYR B CG 1 ATOM 3367 C CD1 . TYR B 2 264 ? 1.677 2.744 -15.303 1.00 82.59 ? 264 TYR B CD1 264 TYR B CD1 1 ATOM 3368 C CD2 . TYR B 2 264 ? -0.057 4.055 -14.312 1.00 82.59 ? 264 TYR B CD2 264 TYR B CD2 1 ATOM 3369 C CE1 . TYR B 2 264 ? 1.878 2.084 -14.095 1.00 82.59 ? 264 TYR B CE1 264 TYR B CE1 1 ATOM 3370 C CE2 . TYR B 2 264 ? 0.135 3.402 -13.099 1.00 82.59 ? 264 TYR B CE2 264 TYR B CE2 1 ATOM 3371 C CZ . TYR B 2 264 ? 1.104 2.420 -13.000 1.00 82.59 ? 264 TYR B CZ 264 TYR B CZ 1 ATOM 3372 O OH . TYR B 2 264 ? 1.298 1.771 -11.802 1.00 82.59 ? 264 TYR B OH 264 TYR B OH 1 ATOM 3373 N N . LYS B 2 265 ? 3.651 5.827 -16.047 1.00 87.82 ? 265 LYS B N 265 LYS B N 1 ATOM 3374 C CA . LYS B 2 265 ? 5.041 5.420 -15.861 1.00 87.82 ? 265 LYS B CA 265 LYS B CA 1 ATOM 3375 C C . LYS B 2 265 ? 5.227 4.685 -14.537 1.00 87.82 ? 265 LYS B C 265 LYS B C 1 ATOM 3376 O O . LYS B 2 265 ? 5.266 5.310 -13.475 1.00 87.82 ? 265 LYS B O 265 LYS B O 1 ATOM 3377 C CB . LYS B 2 265 ? 5.969 6.634 -15.922 1.00 87.82 ? 265 LYS B CB 265 LYS B CB 1 ATOM 3378 C CG . LYS B 2 265 ? 7.446 6.280 -16.012 1.00 87.82 ? 265 LYS B CG 265 LYS B CG 1 ATOM 3379 C CD . LYS B 2 265 ? 8.307 7.521 -16.209 1.00 87.82 ? 265 LYS B CD 265 LYS B CD 1 ATOM 3380 C CE . LYS B 2 265 ? 9.788 7.172 -16.270 1.00 87.82 ? 265 LYS B CE 265 LYS B CE 1 ATOM 3381 N NZ . LYS B 2 265 ? 10.634 8.382 -16.492 1.00 87.82 ? 265 LYS B NZ 265 LYS B NZ 1 ATOM 3382 N N . GLY B 2 266 ? 5.369 3.357 -14.610 1.00 89.64 ? 266 GLY B N 266 GLY B N 1 ATOM 3383 C CA . GLY B 2 266 ? 5.556 2.607 -13.378 1.00 89.64 ? 266 GLY B CA 266 GLY B CA 1 ATOM 3384 C C . GLY B 2 266 ? 5.481 1.105 -13.576 1.00 89.64 ? 266 GLY B C 266 GLY B C 1 ATOM 3385 O O . GLY B 2 266 ? 5.005 0.634 -14.611 1.00 89.64 ? 266 GLY B O 266 GLY B O 1 ATOM 3386 N N . VAL B 2 267 ? 6.066 0.444 -12.611 1.00 93.27 ? 267 VAL B N 267 VAL B N 1 ATOM 3387 C CA . VAL B 2 267 ? 6.038 -1.015 -12.581 1.00 93.27 ? 267 VAL B CA 267 VAL B CA 1 ATOM 3388 C C . VAL B 2 267 ? 4.956 -1.491 -11.615 1.00 93.27 ? 267 VAL B C 267 VAL B C 1 ATOM 3389 O O . VAL B 2 267 ? 4.892 -1.035 -10.471 1.00 93.27 ? 267 VAL B O 267 VAL B O 1 ATOM 3390 C CB . VAL B 2 267 ? 7.409 -1.601 -12.177 1.00 93.27 ? 267 VAL B CB 267 VAL B CB 1 ATOM 3391 C CG1 . VAL B 2 267 ? 7.368 -3.128 -12.190 1.00 93.27 ? 267 VAL B CG1 267 VAL B CG1 1 ATOM 3392 C CG2 . VAL B 2 267 ? 8.505 -1.085 -13.107 1.00 93.27 ? 267 VAL B CG2 267 VAL B CG2 1 ATOM 3393 N N . VAL B 2 268 ? 4.103 -2.411 -12.128 1.00 92.39 ? 268 VAL B N 268 VAL B N 1 ATOM 3394 C CA . VAL B 2 268 ? 3.037 -2.946 -11.287 1.00 92.39 ? 268 VAL B CA 268 VAL B CA 1 ATOM 3395 C C . VAL B 2 268 ? 3.084 -4.472 -11.301 1.00 92.39 ? 268 VAL B C 268 VAL B C 1 ATOM 3396 O O . VAL B 2 268 ? 3.475 -5.078 -12.302 1.00 92.39 ? 268 VAL B O 268 VAL B O 1 ATOM 3397 C CB . VAL B 2 268 ? 1.648 -2.452 -11.749 1.00 92.39 ? 268 VAL B CB 268 VAL B CB 1 ATOM 3398 C CG1 . VAL B 2 268 ? 0.544 -3.053 -10.880 1.00 92.39 ? 268 VAL B CG1 268 VAL B CG1 1 ATOM 3399 C CG2 . VAL B 2 268 ? 1.586 -0.926 -11.716 1.00 92.39 ? 268 VAL B CG2 268 VAL B CG2 1 ATOM 3400 N N . TRP B 2 269 ? 2.710 -5.022 -10.128 1.00 94.61 ? 269 TRP B N 269 TRP B N 1 ATOM 3401 C CA . TRP B 2 269 ? 2.621 -6.474 -10.018 1.00 94.61 ? 269 TRP B CA 269 TRP B CA 1 ATOM 3402 C C . TRP B 2 269 ? 1.166 -6.927 -9.954 1.00 94.61 ? 269 TRP B C 269 TRP B C 1 ATOM 3403 O O . TRP B 2 269 ? 0.416 -6.504 -9.071 1.00 94.61 ? 269 TRP B O 269 TRP B O 1 ATOM 3404 C CB . TRP B 2 269 ? 3.377 -6.969 -8.782 1.00 94.61 ? 269 TRP B CB 269 TRP B CB 1 ATOM 3405 C CG . TRP B 2 269 ? 4.869 -6.920 -8.921 1.00 94.61 ? 269 TRP B CG 269 TRP B CG 1 ATOM 3406 C CD1 . TRP B 2 269 ? 5.693 -7.934 -9.324 1.00 94.61 ? 269 TRP B CD1 269 TRP B CD1 1 ATOM 3407 C CD2 . TRP B 2 269 ? 5.716 -5.799 -8.652 1.00 94.61 ? 269 TRP B CD2 269 TRP B CD2 1 ATOM 3408 N NE1 . TRP B 2 269 ? 7.001 -7.510 -9.323 1.00 94.61 ? 269 TRP B NE1 269 TRP B NE1 1 ATOM 3409 C CE2 . TRP B 2 269 ? 7.043 -6.204 -8.915 1.00 94.61 ? 269 TRP B CE2 269 TRP B CE2 1 ATOM 3410 C CE3 . TRP B 2 269 ? 5.481 -4.488 -8.215 1.00 94.61 ? 269 TRP B CE3 269 TRP B CE3 1 ATOM 3411 C CZ2 . TRP B 2 269 ? 8.133 -5.345 -8.754 1.00 94.61 ? 269 TRP B CZ2 269 TRP B CZ2 1 ATOM 3412 C CZ3 . TRP B 2 269 ? 6.567 -3.634 -8.056 1.00 94.61 ? 269 TRP B CZ3 269 TRP B CZ3 1 ATOM 3413 C CH2 . TRP B 2 269 ? 7.875 -4.068 -8.326 1.00 94.61 ? 269 TRP B CH2 269 TRP B CH2 1 ATOM 3414 N N . THR B 2 270 ? 0.763 -7.704 -10.948 1.00 92.07 ? 270 THR B N 270 THR B N 1 ATOM 3415 C CA . THR B 2 270 ? -0.580 -8.270 -11.012 1.00 92.07 ? 270 THR B CA 270 THR B CA 1 ATOM 3416 C C . THR B 2 270 ? -0.521 -9.780 -11.224 1.00 92.07 ? 270 THR B C 270 THR B C 1 ATOM 3417 O O . THR B 2 270 ? 0.565 -10.358 -11.306 1.00 92.07 ? 270 THR B O 270 THR B O 1 ATOM 3418 C CB . THR B 2 270 ? -1.406 -7.623 -12.139 1.00 92.07 ? 270 THR B CB 270 THR B CB 1 ATOM 3419 O OG1 . THR B 2 270 ? -0.788 -7.908 -13.401 1.00 92.07 ? 270 THR B OG1 270 THR B OG1 1 ATOM 3420 C CG2 . THR B 2 270 ? -1.492 -6.111 -11.959 1.00 92.07 ? 270 THR B CG2 270 THR B CG2 1 ATOM 3421 N N . GLU B 2 271 ? -1.665 -10.371 -11.166 1.00 92.69 ? 271 GLU B N 271 GLU B N 1 ATOM 3422 C CA . GLU B 2 271 ? -1.755 -11.807 -11.411 1.00 92.69 ? 271 GLU B CA 271 GLU B CA 1 ATOM 3423 C C . GLU B 2 271 ? -1.264 -12.160 -12.813 1.00 92.69 ? 271 GLU B C 271 GLU B C 1 ATOM 3424 O O . GLU B 2 271 ? -0.669 -13.220 -13.019 1.00 92.69 ? 271 GLU B O 271 GLU B O 1 ATOM 3425 C CB . GLU B 2 271 ? -3.192 -12.297 -11.219 1.00 92.69 ? 271 GLU B CB 271 GLU B CB 1 ATOM 3426 C CG . GLU B 2 271 ? -3.683 -12.215 -9.781 1.00 92.69 ? 271 GLU B CG 271 GLU B CG 1 ATOM 3427 C CD . GLU B 2 271 ? -4.307 -10.873 -9.435 1.00 92.69 ? 271 GLU B CD 271 GLU B CD 1 ATOM 3428 O OE1 . GLU B 2 271 ? -4.967 -10.764 -8.376 1.00 92.69 ? 271 GLU B OE1 271 GLU B OE1 1 ATOM 3429 O OE2 . GLU B 2 271 ? -4.136 -9.921 -10.230 1.00 92.69 ? 271 GLU B OE2 271 GLU B OE2 1 ATOM 3430 N N . SER B 2 272 ? -1.483 -11.306 -13.750 1.00 90.45 ? 272 SER B N 272 SER B N 1 ATOM 3431 C CA . SER B 2 272 ? -1.074 -11.523 -15.134 1.00 90.45 ? 272 SER B CA 272 SER B CA 1 ATOM 3432 C C . SER B 2 272 ? 0.438 -11.691 -15.244 1.00 90.45 ? 272 SER B C 272 SER B C 1 ATOM 3433 O O . SER B 2 272 ? 0.923 -12.471 -16.065 1.00 90.45 ? 272 SER B O 272 SER B O 1 ATOM 3434 C CB . SER B 2 272 ? -1.532 -10.362 -16.018 1.00 90.45 ? 272 SER B CB 272 SER B CB 1 ATOM 3435 O OG . SER B 2 272 ? -0.921 -9.150 -15.612 1.00 90.45 ? 272 SER B OG 272 SER B OG 1 ATOM 3436 N N . HIS B 2 273 ? 1.144 -10.996 -14.448 1.00 91.59 ? 273 HIS B N 273 HIS B N 1 ATOM 3437 C CA . HIS B 2 273 ? 2.600 -11.073 -14.467 1.00 91.59 ? 273 HIS B CA 273 HIS B CA 1 ATOM 3438 C C . HIS B 2 273 ? 3.089 -12.402 -13.899 1.00 91.59 ? 273 HIS B C 273 HIS B C 1 ATOM 3439 O O . HIS B 2 273 ? 4.111 -12.932 -14.340 1.00 91.59 ? 273 HIS B O 273 HIS B O 1 ATOM 3440 C CB . HIS B 2 273 ? 3.208 -9.911 -13.680 1.00 91.59 ? 273 HIS B CB 273 HIS B CB 1 ATOM 3441 C CG . HIS B 2 273 ? 2.924 -8.569 -14.277 1.00 91.59 ? 273 HIS B CG 273 HIS B CG 1 ATOM 3442 N ND1 . HIS B 2 273 ? 1.928 -7.741 -13.805 1.00 91.59 ? 273 HIS B ND1 273 HIS B ND1 1 ATOM 3443 C CD2 . HIS B 2 273 ? 3.509 -7.912 -15.305 1.00 91.59 ? 273 HIS B CD2 273 HIS B CD2 1 ATOM 3444 C CE1 . HIS B 2 273 ? 1.913 -6.629 -14.522 1.00 91.59 ? 273 HIS B CE1 273 HIS B CE1 1 ATOM 3445 N NE2 . HIS B 2 273 ? 2.862 -6.708 -15.439 1.00 91.59 ? 273 HIS B NE2 273 HIS B NE2 1 ATOM 3446 N N . GLN B 2 274 ? 2.436 -12.876 -12.909 1.00 92.33 ? 274 GLN B N 274 GLN B N 1 ATOM 3447 C CA . GLN B 2 274 ? 2.759 -14.201 -12.390 1.00 92.33 ? 274 GLN B CA 274 GLN B CA 1 ATOM 3448 C C . GLN B 2 274 ? 2.543 -15.276 -13.452 1.00 92.33 ? 274 GLN B C 274 GLN B C 1 ATOM 3449 O O . GLN B 2 274 ? 3.328 -16.221 -13.554 1.00 92.33 ? 274 GLN B O 274 GLN B O 1 ATOM 3450 C CB . GLN B 2 274 ? 1.919 -14.512 -11.150 1.00 92.33 ? 274 GLN B CB 274 GLN B CB 1 ATOM 3451 C CG . GLN B 2 274 ? 2.253 -13.640 -9.947 1.00 92.33 ? 274 GLN B CG 274 GLN B CG 1 ATOM 3452 C CD . GLN B 2 274 ? 1.467 -14.024 -8.708 1.00 92.33 ? 274 GLN B CD 274 GLN B CD 1 ATOM 3453 O OE1 . GLN B 2 274 ? 1.605 -15.136 -8.189 1.00 92.33 ? 274 GLN B OE1 274 GLN B OE1 1 ATOM 3454 N NE2 . GLN B 2 274 ? 0.636 -13.107 -8.224 1.00 92.33 ? 274 GLN B NE2 274 GLN B NE2 1 ATOM 3455 N N . GLU B 2 275 ? 1.467 -15.088 -14.243 1.00 90.81 ? 275 GLU B N 275 GLU B N 1 ATOM 3456 C CA . GLU B 2 275 ? 1.204 -15.991 -15.360 1.00 90.81 ? 275 GLU B CA 275 GLU B CA 1 ATOM 3457 C C . GLU B 2 275 ? 2.310 -15.910 -16.408 1.00 90.81 ? 275 GLU B C 275 GLU B C 1 ATOM 3458 O O . GLU B 2 275 ? 2.810 -16.937 -16.871 1.00 90.81 ? 275 GLU B O 275 GLU B O 1 ATOM 3459 C CB . GLU B 2 275 ? -0.151 -15.676 -15.999 1.00 90.81 ? 275 GLU B CB 275 GLU B CB 1 ATOM 3460 C CG . GLU B 2 275 ? -0.506 -16.585 -17.167 1.00 90.81 ? 275 GLU B CG 275 GLU B CG 1 ATOM 3461 C CD . GLU B 2 275 ? -1.804 -16.197 -17.856 1.00 90.81 ? 275 GLU B CD 275 GLU B CD 1 ATOM 3462 O OE1 . GLU B 2 275 ? -2.487 -17.087 -18.411 1.00 90.81 ? 275 GLU B OE1 275 GLU B OE1 1 ATOM 3463 O OE2 . GLU B 2 275 ? -2.141 -14.992 -17.842 1.00 90.81 ? 275 GLU B OE2 275 GLU B OE2 1 ATOM 3464 N N . ALA B 2 276 ? 2.691 -14.696 -16.694 1.00 89.30 ? 276 ALA B N 276 ALA B N 1 ATOM 3465 C CA . ALA B 2 276 ? 3.745 -14.473 -17.680 1.00 89.30 ? 276 ALA B CA 276 ALA B CA 1 ATOM 3466 C C . ALA B 2 276 ? 5.068 -15.074 -17.215 1.00 89.30 ? 276 ALA B C 276 ALA B C 1 ATOM 3467 O O . ALA B 2 276 ? 5.815 -15.640 -18.016 1.00 89.30 ? 276 ALA B O 276 ALA B O 1 ATOM 3468 C CB . ALA B 2 276 ? 3.909 -12.981 -17.955 1.00 89.30 ? 276 ALA B CB 276 ALA B CB 1 ATOM 3469 N N . ASP B 2 277 ? 5.344 -14.886 -15.954 1.00 89.30 ? 277 ASP B N 277 ASP B N 1 ATOM 3470 C CA . ASP B 2 277 ? 6.570 -15.435 -15.384 1.00 89.30 ? 277 ASP B CA 277 ASP B CA 1 ATOM 3471 C C . ASP B 2 277 ? 6.581 -16.959 -15.469 1.00 89.30 ? 277 ASP B C 277 ASP B C 1 ATOM 3472 O O . ASP B 2 277 ? 7.608 -17.561 -15.788 1.00 89.30 ? 277 ASP B O 277 ASP B O 1 ATOM 3473 C CB . ASP B 2 277 ? 6.732 -14.988 -13.929 1.00 89.30 ? 277 ASP B CB 277 ASP B CB 1 ATOM 3474 C CG . ASP B 2 277 ? 8.105 -15.303 -13.362 1.00 89.30 ? 277 ASP B CG 277 ASP B CG 1 ATOM 3475 O OD1 . ASP B 2 277 ? 9.096 -15.295 -14.124 1.00 89.30 ? 277 ASP B OD1 277 ASP B OD1 1 ATOM 3476 O OD2 . ASP B 2 277 ? 8.197 -15.564 -12.143 1.00 89.30 ? 277 ASP B OD2 277 ASP B OD2 1 ATOM 3477 N N . LEU B 2 278 ? 5.487 -17.569 -15.205 1.00 86.56 ? 278 LEU B N 278 LEU B N 1 ATOM 3478 C CA . LEU B 2 278 ? 5.373 -19.021 -15.290 1.00 86.56 ? 278 LEU B CA 278 LEU B CA 1 ATOM 3479 C C . LEU B 2 278 ? 5.561 -19.498 -16.727 1.00 86.56 ? 278 LEU B C 278 LEU B C 1 ATOM 3480 O O . LEU B 2 278 ? 6.240 -20.499 -16.969 1.00 86.56 ? 278 LEU B O 278 LEU B O 1 ATOM 3481 C CB . LEU B 2 278 ? 4.014 -19.484 -14.760 1.00 86.56 ? 278 LEU B CB 278 LEU B CB 1 ATOM 3482 C CG . LEU B 2 278 ? 3.812 -20.996 -14.641 1.00 86.56 ? 278 LEU B CG 278 LEU B CG 1 ATOM 3483 C CD1 . LEU B 2 278 ? 4.803 -21.585 -13.642 1.00 86.56 ? 278 LEU B CD1 278 LEU B CD1 1 ATOM 3484 C CD2 . LEU B 2 278 ? 2.378 -21.313 -14.230 1.00 86.56 ? 278 LEU B CD2 278 LEU B CD2 1 ATOM 3485 N N . LEU B 2 279 ? 5.070 -18.789 -17.640 1.00 85.78 ? 279 LEU B N 279 LEU B N 1 ATOM 3486 C CA . LEU B 2 279 ? 5.163 -19.135 -19.054 1.00 85.78 ? 279 LEU B CA 279 LEU B CA 1 ATOM 3487 C C . LEU B 2 279 ? 6.592 -18.971 -19.560 1.00 85.78 ? 279 LEU B C 279 LEU B C 1 ATOM 3488 O O . LEU B 2 279 ? 7.033 -19.715 -20.439 1.00 85.78 ? 279 LEU B O 279 LEU B O 1 ATOM 3489 C CB . LEU B 2 279 ? 4.213 -18.266 -19.882 1.00 85.78 ? 279 LEU B CB 279 LEU B CB 1 ATOM 3490 C CG . LEU B 2 279 ? 2.726 -18.611 -19.790 1.00 85.78 ? 279 LEU B CG 279 LEU B CG 1 ATOM 3491 C CD1 . LEU B 2 279 ? 1.890 -17.543 -20.488 1.00 85.78 ? 279 LEU B CD1 279 LEU B CD1 1 ATOM 3492 C CD2 . LEU B 2 279 ? 2.457 -19.986 -20.393 1.00 85.78 ? 279 LEU B CD2 279 LEU B CD2 1 ATOM 3493 N N . SER B 2 280 ? 7.262 -17.970 -19.017 1.00 84.14 ? 280 SER B N 280 SER B N 1 ATOM 3494 C CA . SER B 2 280 ? 8.633 -17.710 -19.444 1.00 84.14 ? 280 SER B CA 280 SER B CA 1 ATOM 3495 C C . SER B 2 280 ? 9.562 -18.852 -19.044 1.00 84.14 ? 280 SER B C 280 SER B C 1 ATOM 3496 O O . SER B 2 280 ? 10.622 -19.037 -19.646 1.00 84.14 ? 280 SER B O 280 SER B O 1 ATOM 3497 C CB . SER B 2 280 ? 9.142 -16.397 -18.848 1.00 84.14 ? 280 SER B CB 280 SER B CB 1 ATOM 3498 O OG . SER B 2 280 ? 9.274 -16.501 -17.441 1.00 84.14 ? 280 SER B OG 280 SER B OG 1 ATOM 3499 N N . ASN B 2 281 ? 9.158 -19.584 -18.090 1.00 79.83 ? 281 ASN B N 281 ASN B N 1 ATOM 3500 C CA . ASN B 2 281 ? 9.951 -20.721 -17.636 1.00 79.83 ? 281 ASN B CA 281 ASN B CA 1 ATOM 3501 C C . ASN B 2 281 ? 9.776 -21.928 -18.553 1.00 79.83 ? 281 ASN B C 281 ASN B C 1 ATOM 3502 O O . ASN B 2 281 ? 10.531 -22.898 -18.461 1.00 79.83 ? 281 ASN B O 281 ASN B O 1 ATOM 3503 C CB . ASN B 2 281 ? 9.586 -21.090 -16.196 1.00 79.83 ? 281 ASN B CB 281 ASN B CB 1 ATOM 3504 C CG . ASN B 2 281 ? 10.042 -20.049 -15.193 1.00 79.83 ? 281 ASN B CG 281 ASN B CG 1 ATOM 3505 O OD1 . ASN B 2 281 ? 10.911 -19.225 -15.487 1.00 79.83 ? 281 ASN B OD1 281 ASN B OD1 1 ATOM 3506 N ND2 . ASN B 2 281 ? 9.458 -20.079 -14.001 1.00 79.83 ? 281 ASN B ND2 281 ASN B ND2 1 ATOM 3507 N N . THR B 2 282 ? 8.849 -21.750 -19.473 1.00 74.11 ? 282 THR B N 282 THR B N 1 ATOM 3508 C CA . THR B 2 282 ? 8.617 -22.818 -20.439 1.00 74.11 ? 282 THR B CA 282 THR B CA 1 ATOM 3509 C C . THR B 2 282 ? 9.490 -22.627 -21.676 1.00 74.11 ? 282 THR B C 282 THR B C 1 ATOM 3510 O O . THR B 2 282 ? 9.854 -21.500 -22.018 1.00 74.11 ? 282 THR B O 282 THR B O 1 ATOM 3511 C CB . THR B 2 282 ? 7.137 -22.881 -20.858 1.00 74.11 ? 282 THR B CB 282 THR B CB 1 ATOM 3512 O OG1 . THR B 2 282 ? 6.315 -22.911 -19.684 1.00 74.11 ? 282 THR B OG1 282 THR B OG1 1 ATOM 3513 C CG2 . THR B 2 282 ? 6.854 -24.124 -21.695 1.00 74.11 ? 282 THR B CG2 282 THR B CG2 1 ATOM 3514 N N . ASP B 2 283 ? 10.123 -23.615 -22.218 1.00 65.06 ? 283 ASP B N 283 ASP B N 1 ATOM 3515 C CA . ASP B 2 283 ? 10.964 -23.619 -23.411 1.00 65.06 ? 283 ASP B CA 283 ASP B CA 1 ATOM 3516 C C . ASP B 2 283 ? 10.148 -23.286 -24.658 1.00 65.06 ? 283 ASP B C 283 ASP B C 1 ATOM 3517 O O . ASP B 2 283 ? 10.706 -23.128 -25.747 1.00 65.06 ? 283 ASP B O 283 ASP B O 1 ATOM 3518 C CB . ASP B 2 283 ? 11.652 -24.975 -23.578 1.00 65.06 ? 283 ASP B CB 283 ASP B CB 1 ATOM 3519 C CG . ASP B 2 283 ? 12.714 -25.235 -22.525 1.00 65.06 ? 283 ASP B CG 283 ASP B CG 1 ATOM 3520 O OD1 . ASP B 2 283 ? 13.316 -24.266 -22.014 1.00 65.06 ? 283 ASP B OD1 283 ASP B OD1 1 ATOM 3521 O OD2 . ASP B 2 283 ? 12.953 -26.420 -22.205 1.00 65.06 ? 283 ASP B OD2 283 ASP B OD2 1 ATOM 3522 N N . ALA B 2 284 ? 8.862 -23.014 -24.492 1.00 57.45 ? 284 ALA B N 284 ALA B N 1 ATOM 3523 C CA . ALA B 2 284 ? 8.024 -22.853 -25.678 1.00 57.45 ? 284 ALA B CA 284 ALA B CA 1 ATOM 3524 C C . ALA B 2 284 ? 8.140 -21.440 -26.243 1.00 57.45 ? 284 ALA B C 284 ALA B C 1 ATOM 3525 O O . ALA B 2 284 ? 7.686 -20.477 -25.621 1.00 57.45 ? 284 ALA B O 284 ALA B O 1 ATOM 3526 C CB . ALA B 2 284 ? 6.568 -23.173 -25.348 1.00 57.45 ? 284 ALA B CB 284 ALA B CB 1 ATOM 3527 N N . LYS B 2 285 ? 9.234 -21.018 -26.771 1.00 54.68 ? 285 LYS B N 285 LYS B N 1 ATOM 3528 C CA . LYS B 2 285 ? 9.542 -19.749 -27.423 1.00 54.68 ? 285 LYS B CA 285 LYS B CA 1 ATOM 3529 C C . LYS B 2 285 ? 8.401 -19.308 -28.335 1.00 54.68 ? 285 LYS B C 285 LYS B C 1 ATOM 3530 O O . LYS B 2 285 ? 8.158 -18.110 -28.500 1.00 54.68 ? 285 LYS B O 285 LYS B O 1 ATOM 3531 C CB . LYS B 2 285 ? 10.840 -19.859 -28.225 1.00 54.68 ? 285 LYS B CB 285 LYS B CB 1 ATOM 3532 C CG . LYS B 2 285 ? 12.100 -19.817 -27.372 1.00 54.68 ? 285 LYS B CG 285 LYS B CG 1 ATOM 3533 C CD . LYS B 2 285 ? 13.357 -19.822 -28.231 1.00 54.68 ? 285 LYS B CD 285 LYS B CD 1 ATOM 3534 C CE . LYS B 2 285 ? 14.618 -19.857 -27.378 1.00 54.68 ? 285 LYS B CE 285 LYS B CE 1 ATOM 3535 N NZ . LYS B 2 285 ? 15.854 -19.816 -28.215 1.00 54.68 ? 285 LYS B NZ 285 LYS B NZ 1 ATOM 3536 N N . ASP B 2 286 ? 7.406 -20.312 -28.685 1.00 49.50 ? 286 ASP B N 286 ASP B N 1 ATOM 3537 C CA . ASP B 2 286 ? 6.423 -19.997 -29.718 1.00 49.50 ? 286 ASP B CA 286 ASP B CA 1 ATOM 3538 C C . ASP B 2 286 ? 5.144 -19.432 -29.105 1.00 49.50 ? 286 ASP B C 286 ASP B C 1 ATOM 3539 O O . ASP B 2 286 ? 4.420 -18.674 -29.754 1.00 49.50 ? 286 ASP B O 286 ASP B O 1 ATOM 3540 C CB . ASP B 2 286 ? 6.102 -21.241 -30.550 1.00 49.50 ? 286 ASP B CB 286 ASP B CB 1 ATOM 3541 C CG . ASP B 2 286 ? 7.117 -21.497 -31.649 1.00 49.50 ? 286 ASP B CG 286 ASP B CG 1 ATOM 3542 O OD1 . ASP B 2 286 ? 7.884 -20.574 -31.999 1.00 49.50 ? 286 ASP B OD1 286 ASP B OD1 1 ATOM 3543 O OD2 . ASP B 2 286 ? 7.150 -22.632 -32.172 1.00 49.50 ? 286 ASP B OD2 286 ASP B OD2 1 ATOM 3544 N N . LEU B 2 287 ? 4.995 -19.470 -27.784 1.00 49.96 ? 287 LEU B N 287 LEU B N 1 ATOM 3545 C CA . LEU B 2 287 ? 3.752 -19.010 -27.173 1.00 49.96 ? 287 LEU B CA 287 LEU B CA 1 ATOM 3546 C C . LEU B 2 287 ? 3.841 -17.533 -26.804 1.00 49.96 ? 287 LEU B C 287 LEU B C 1 ATOM 3547 O O . LEU B 2 287 ? 2.818 -16.856 -26.685 1.00 49.96 ? 287 LEU B O 287 LEU B O 1 ATOM 3548 C CB . LEU B 2 287 ? 3.427 -19.840 -25.929 1.00 49.96 ? 287 LEU B CB 287 LEU B CB 1 ATOM 3549 C CG . LEU B 2 287 ? 2.827 -21.225 -26.175 1.00 49.96 ? 287 LEU B CG 287 LEU B CG 1 ATOM 3550 C CD1 . LEU B 2 287 ? 3.246 -22.189 -25.070 1.00 49.96 ? 287 LEU B CD1 287 LEU B CD1 1 ATOM 3551 C CD2 . LEU B 2 287 ? 1.307 -21.140 -26.269 1.00 49.96 ? 287 LEU B CD2 287 LEU B CD2 1 ATOM 3552 N N . THR B 2 288 ? 5.146 -16.974 -26.762 1.00 47.12 ? 288 THR B N 288 THR B N 1 ATOM 3553 C CA . THR B 2 288 ? 5.390 -15.580 -26.410 1.00 47.12 ? 288 THR B CA 288 THR B CA 1 ATOM 3554 C C . THR B 2 288 ? 4.963 -14.652 -27.544 1.00 47.12 ? 288 THR B C 288 THR B C 1 ATOM 3555 O O . THR B 2 288 ? 4.717 -13.465 -27.322 1.00 47.12 ? 288 THR B O 288 THR B O 1 ATOM 3556 C CB . THR B 2 288 ? 6.875 -15.339 -26.078 1.00 47.12 ? 288 THR B CB 288 THR B CB 1 ATOM 3557 O OG1 . THR B 2 288 ? 7.686 -15.863 -27.137 1.00 47.12 ? 288 THR B OG1 288 THR B OG1 1 ATOM 3558 C CG2 . THR B 2 288 ? 7.264 -16.020 -24.770 1.00 47.12 ? 288 THR B CG2 288 THR B CG2 1 ATOM 3559 N N . VAL B 2 289 ? 4.461 -15.280 -28.759 1.00 41.85 ? 289 VAL B N 289 VAL B N 1 ATOM 3560 C CA . VAL B 2 289 ? 4.147 -14.458 -29.923 1.00 41.85 ? 289 VAL B CA 289 VAL B CA 1 ATOM 3561 C C . VAL B 2 289 ? 2.676 -14.051 -29.887 1.00 41.85 ? 289 VAL B C 289 VAL B C 1 ATOM 3562 O O . VAL B 2 289 ? 2.263 -13.128 -30.593 1.00 41.85 ? 289 VAL B O 289 VAL B O 1 ATOM 3563 C CB . VAL B 2 289 ? 4.464 -15.197 -31.242 1.00 41.85 ? 289 VAL B CB 289 VAL B CB 1 ATOM 3564 C CG1 . VAL B 2 289 ? 4.078 -14.341 -32.447 1.00 41.85 ? 289 VAL B CG1 289 VAL B CG1 1 ATOM 3565 C CG2 . VAL B 2 289 ? 5.944 -15.571 -31.301 1.00 41.85 ? 289 VAL B CG2 289 VAL B CG2 1 ATOM 3566 N N . VAL B 2 290 ? 1.965 -14.349 -28.799 1.00 39.87 ? 290 VAL B N 290 VAL B N 1 ATOM 3567 C CA . VAL B 2 290 ? 0.680 -13.660 -28.866 1.00 39.87 ? 290 VAL B CA 290 VAL B CA 1 ATOM 3568 C C . VAL B 2 290 ? 0.771 -12.323 -28.135 1.00 39.87 ? 290 VAL B C 290 VAL B C 1 ATOM 3569 O O . VAL B 2 290 ? 0.803 -12.283 -26.903 1.00 39.87 ? 290 VAL B O 290 VAL B O 1 ATOM 3570 C CB . VAL B 2 290 ? -0.457 -14.519 -28.267 1.00 39.87 ? 290 VAL B CB 290 VAL B CB 1 ATOM 3571 C CG1 . VAL B 2 290 ? -1.790 -13.777 -28.340 1.00 39.87 ? 290 VAL B CG1 290 VAL B CG1 1 ATOM 3572 C CG2 . VAL B 2 290 ? -0.549 -15.861 -28.991 1.00 39.87 ? 290 VAL B CG2 290 VAL B CG2 1 ATOM 3573 N N . ASP B 2 291 ? 2.033 -11.697 -28.074 1.00 41.37 ? 291 ASP B N 291 ASP B N 1 ATOM 3574 C CA . ASP B 2 291 ? 2.262 -10.280 -27.810 1.00 41.37 ? 291 ASP B CA 291 ASP B CA 1 ATOM 3575 C C . ASP B 2 291 ? 1.167 -9.420 -28.437 1.00 41.37 ? 291 ASP B C 291 ASP B C 1 ATOM 3576 O O . ASP B 2 291 ? 0.861 -9.563 -29.622 1.00 41.37 ? 291 ASP B O 291 ASP B O 1 ATOM 3577 C CB . ASP B 2 291 ? 3.634 -9.852 -28.337 1.00 41.37 ? 291 ASP B CB 291 ASP B CB 1 ATOM 3578 C CG . ASP B 2 291 ? 4.513 -9.232 -27.266 1.00 41.37 ? 291 ASP B CG 291 ASP B CG 1 ATOM 3579 O OD1 . ASP B 2 291 ? 4.034 -9.020 -26.131 1.00 41.37 ? 291 ASP B OD1 291 ASP B OD1 1 ATOM 3580 O OD2 . ASP B 2 291 ? 5.695 -8.951 -27.560 1.00 41.37 ? 291 ASP B OD2 291 ASP B OD2 1 ATOM 3581 N N . ARG B 2 292 ? -0.096 -9.344 -28.005 1.00 41.39 ? 292 ARG B N 292 ARG B N 1 ATOM 3582 C CA . ARG B 2 292 ? -0.809 -8.107 -28.306 1.00 41.39 ? 292 ARG B CA 292 ARG B CA 1 ATOM 3583 C C . ARG B 2 292 ? 0.137 -7.053 -28.871 1.00 41.39 ? 292 ARG B C 292 ARG B C 1 ATOM 3584 O O . ARG B 2 292 ? 1.207 -6.807 -28.311 1.00 41.39 ? 292 ARG B O 292 ARG B O 1 ATOM 3585 C CB . ARG B 2 292 ? -1.506 -7.569 -27.054 1.00 41.39 ? 292 ARG B CB 292 ARG B CB 1 ATOM 3586 C CG . ARG B 2 292 ? -2.760 -8.336 -26.669 1.00 41.39 ? 292 ARG B CG 292 ARG B CG 1 ATOM 3587 C CD . ARG B 2 292 ? -3.517 -7.650 -25.540 1.00 41.39 ? 292 ARG B CD 292 ARG B CD 1 ATOM 3588 N NE . ARG B 2 292 ? -4.745 -8.365 -25.202 1.00 41.39 ? 292 ARG B NE 292 ARG B NE 1 ATOM 3589 C CZ . ARG B 2 292 ? -5.637 -7.955 -24.305 1.00 41.39 ? 292 ARG B CZ 292 ARG B CZ 1 ATOM 3590 N NH1 . ARG B 2 292 ? -5.455 -6.823 -23.635 1.00 41.39 ? 292 ARG B NH1 292 ARG B NH1 1 ATOM 3591 N NH2 . ARG B 2 292 ? -6.721 -8.683 -24.075 1.00 41.39 ? 292 ARG B NH2 292 ARG B NH2 1 ATOM 3592 N N . GLY B 2 293 ? 0.643 -7.221 -30.115 1.00 37.77 ? 293 GLY B N 293 GLY B N 1 ATOM 3593 C CA . GLY B 2 293 ? 0.698 -6.103 -31.044 1.00 37.77 ? 293 GLY B CA 293 GLY B CA 1 ATOM 3594 C C . GLY B 2 293 ? 1.965 -5.279 -30.911 1.00 37.77 ? 293 GLY B C 293 GLY B C 1 ATOM 3595 O O . GLY B 2 293 ? 2.406 -4.984 -29.798 1.00 37.77 ? 293 GLY B O 293 GLY B O 1 ATOM 3596 N N . GLN B 2 294 ? 3.106 -5.684 -31.311 1.00 34.33 ? 294 GLN B N 294 GLN B N 1 ATOM 3597 C CA . GLN B 2 294 ? 3.859 -4.757 -32.150 1.00 34.33 ? 294 GLN B CA 294 GLN B CA 1 ATOM 3598 C C . GLN B 2 294 ? 3.648 -3.314 -31.701 1.00 34.33 ? 294 GLN B C 294 GLN B C 1 ATOM 3599 O O . GLN B 2 294 ? 2.521 -2.815 -31.704 1.00 34.33 ? 294 GLN B O 294 GLN B O 1 ATOM 3600 C CB . GLN B 2 294 ? 3.459 -4.914 -33.618 1.00 34.33 ? 294 GLN B CB 294 GLN B CB 1 ATOM 3601 C CG . GLN B 2 294 ? 4.284 -5.948 -34.373 1.00 34.33 ? 294 GLN B CG 294 GLN B CG 1 ATOM 3602 C CD . GLN B 2 294 ? 3.902 -6.048 -35.837 1.00 34.33 ? 294 GLN B CD 294 GLN B CD 1 ATOM 3603 O OE1 . GLN B 2 294 ? 3.075 -5.274 -36.331 1.00 34.33 ? 294 GLN B OE1 294 GLN B OE1 1 ATOM 3604 N NE2 . GLN B 2 294 ? 4.500 -7.001 -36.543 1.00 34.33 ? 294 GLN B NE2 294 GLN B NE2 1 ATOM 3605 N N . SER B 2 295 ? 3.923 -2.993 -30.413 1.00 39.68 ? 295 SER B N 295 SER B N 1 ATOM 3606 C CA . SER B 2 295 ? 4.344 -1.627 -30.119 1.00 39.68 ? 295 SER B CA 295 SER B CA 1 ATOM 3607 C C . SER B 2 295 ? 4.743 -0.886 -31.391 1.00 39.68 ? 295 SER B C 295 SER B C 1 ATOM 3608 O O . SER B 2 295 ? 5.580 -1.366 -32.159 1.00 39.68 ? 295 SER B O 295 SER B O 1 ATOM 3609 C CB . SER B 2 295 ? 5.512 -1.627 -29.132 1.00 39.68 ? 295 SER B CB 295 SER B CB 1 ATOM 3610 O OG . SER B 2 295 ? 6.639 -2.284 -29.686 1.00 39.68 ? 295 SER B OG 295 SER B OG 1 ATOM 3611 N N . THR B 2 296 ? 3.929 -0.865 -32.444 1.00 35.39 ? 296 THR B N 296 THR B N 1 ATOM 3612 C CA . THR B 2 296 ? 4.262 0.298 -33.259 1.00 35.39 ? 296 THR B CA 296 THR B CA 1 ATOM 3613 C C . THR B 2 296 ? 5.128 1.279 -32.475 1.00 35.39 ? 296 THR B C 296 THR B C 1 ATOM 3614 O O . THR B 2 296 ? 4.915 1.483 -31.277 1.00 35.39 ? 296 THR B O 296 THR B O 1 ATOM 3615 C CB . THR B 2 296 ? 2.993 1.013 -33.757 1.00 35.39 ? 296 THR B CB 296 THR B CB 1 ATOM 3616 O OG1 . THR B 2 296 ? 2.095 1.202 -32.656 1.00 35.39 ? 296 THR B OG1 296 THR B OG1 1 ATOM 3617 C CG2 . THR B 2 296 ? 2.289 0.198 -34.837 1.00 35.39 ? 296 THR B CG2 296 THR B CG2 1 ATOM 3618 N N . PRO B 2 297 ? 6.497 1.359 -32.748 1.00 41.30 ? 297 PRO B N 297 PRO B N 1 ATOM 3619 C CA . PRO B 2 297 ? 7.306 2.434 -32.170 1.00 41.30 ? 297 PRO B CA 297 PRO B CA 1 ATOM 3620 C C . PRO B 2 297 ? 6.594 3.785 -32.191 1.00 41.30 ? 297 PRO B C 297 PRO B C 1 ATOM 3621 O O . PRO B 2 297 ? 7.245 4.831 -32.145 1.00 41.30 ? 297 PRO B O 297 PRO B O 1 ATOM 3622 C CB . PRO B 2 297 ? 8.549 2.459 -33.062 1.00 41.30 ? 297 PRO B CB 297 PRO B CB 1 ATOM 3623 C CG . PRO B 2 297 ? 8.119 1.803 -34.334 1.00 41.30 ? 297 PRO B CG 297 PRO B CG 1 ATOM 3624 C CD . PRO B 2 297 ? 6.691 1.364 -34.186 1.00 41.30 ? 297 PRO B CD 297 PRO B CD 1 ATOM 3625 N N . PHE B 2 298 ? 5.157 3.797 -32.273 1.00 38.82 ? 298 PHE B N 298 PHE B N 1 ATOM 3626 C CA . PHE B 2 298 ? 4.635 5.140 -32.054 1.00 38.82 ? 298 PHE B CA 298 PHE B CA 1 ATOM 3627 C C . PHE B 2 298 ? 4.469 5.421 -30.565 1.00 38.82 ? 298 PHE B C 298 PHE B C 1 ATOM 3628 O O . PHE B 2 298 ? 4.032 4.551 -29.809 1.00 38.82 ? 298 PHE B O 298 PHE B O 1 ATOM 3629 C CB . PHE B 2 298 ? 3.296 5.322 -32.775 1.00 38.82 ? 298 PHE B CB 298 PHE B CB 1 ATOM 3630 C CG . PHE B 2 298 ? 3.422 5.446 -34.269 1.00 38.82 ? 298 PHE B CG 298 PHE B CG 1 ATOM 3631 C CD1 . PHE B 2 298 ? 3.862 6.630 -34.848 1.00 38.82 ? 298 PHE B CD1 298 PHE B CD1 1 ATOM 3632 C CD2 . PHE B 2 298 ? 3.101 4.376 -35.095 1.00 38.82 ? 298 PHE B CD2 298 PHE B CD2 1 ATOM 3633 C CE1 . PHE B 2 298 ? 3.981 6.746 -36.231 1.00 38.82 ? 298 PHE B CE1 298 PHE B CE1 1 ATOM 3634 C CE2 . PHE B 2 298 ? 3.217 4.486 -36.478 1.00 38.82 ? 298 PHE B CE2 298 PHE B CE2 1 ATOM 3635 C CZ . PHE B 2 298 ? 3.656 5.672 -37.044 1.00 38.82 ? 298 PHE B CZ 298 PHE B CZ 1 ATOM 3636 N N . THR B 2 299 ? 5.507 5.620 -29.753 1.00 43.15 ? 299 THR B N 299 THR B N 1 ATOM 3637 C CA . THR B 2 299 ? 5.443 6.269 -28.448 1.00 43.15 ? 299 THR B CA 299 THR B CA 1 ATOM 3638 C C . THR B 2 299 ? 3.994 6.497 -28.028 1.00 43.15 ? 299 THR B C 299 THR B C 1 ATOM 3639 O O . THR B 2 299 ? 3.310 7.360 -28.581 1.00 43.15 ? 299 THR B O 299 THR B O 1 ATOM 3640 C CB . THR B 2 299 ? 6.196 7.613 -28.456 1.00 43.15 ? 299 THR B CB 299 THR B CB 1 ATOM 3641 O OG1 . THR B 2 299 ? 6.019 8.246 -29.729 1.00 43.15 ? 299 THR B OG1 299 THR B OG1 1 ATOM 3642 C CG2 . THR B 2 299 ? 7.686 7.410 -28.204 1.00 43.15 ? 299 THR B CG2 299 THR B CG2 1 ATOM 3643 N N . ASN B 2 300 ? 2.983 5.480 -28.267 1.00 45.73 ? 300 ASN B N 300 ASN B N 1 ATOM 3644 C CA . ASN B 2 300 ? 1.585 5.703 -27.915 1.00 45.73 ? 300 ASN B CA 300 ASN B CA 1 ATOM 3645 C C . ASN B 2 300 ? 1.405 5.859 -26.407 1.00 45.73 ? 300 ASN B C 300 ASN B C 1 ATOM 3646 O O . ASN B 2 300 ? 1.949 5.075 -25.628 1.00 45.73 ? 300 ASN B O 300 ASN B O 1 ATOM 3647 C CB . ASN B 2 300 ? 0.711 4.561 -28.438 1.00 45.73 ? 300 ASN B CB 300 ASN B CB 1 ATOM 3648 C CG . ASN B 2 300 ? 0.323 4.742 -29.892 1.00 45.73 ? 300 ASN B CG 300 ASN B CG 1 ATOM 3649 O OD1 . ASN B 2 300 ? 0.371 5.853 -30.426 1.00 45.73 ? 300 ASN B OD1 300 ASN B OD1 1 ATOM 3650 N ND2 . ASN B 2 300 ? -0.065 3.651 -30.543 1.00 45.73 ? 300 ASN B ND2 300 ASN B ND2 1 ATOM 3651 N N . VAL B 2 301 ? 1.736 6.961 -25.805 1.00 55.87 ? 301 VAL B N 301 VAL B N 1 ATOM 3652 C CA . VAL B 2 301 ? 1.182 7.404 -24.530 1.00 55.87 ? 301 VAL B CA 301 VAL B CA 1 ATOM 3653 C C . VAL B 2 301 ? 0.031 6.488 -24.121 1.00 55.87 ? 301 VAL B C 301 VAL B C 1 ATOM 3654 O O . VAL B 2 301 ? -1.009 6.455 -24.782 1.00 55.87 ? 301 VAL B O 301 VAL B O 1 ATOM 3655 C CB . VAL B 2 301 ? 0.699 8.869 -24.600 1.00 55.87 ? 301 VAL B CB 301 VAL B CB 1 ATOM 3656 C CG1 . VAL B 2 301 ? 0.190 9.335 -23.237 1.00 55.87 ? 301 VAL B CG1 301 VAL B CG1 1 ATOM 3657 C CG2 . VAL B 2 301 ? 1.823 9.779 -25.093 1.00 55.87 ? 301 VAL B CG2 301 VAL B CG2 1 ATOM 3658 N N . SER B 2 302 ? 0.359 5.244 -23.761 1.00 67.73 ? 302 SER B N 302 SER B N 1 ATOM 3659 C CA . SER B 2 302 ? -0.684 4.315 -23.339 1.00 67.73 ? 302 SER B CA 302 SER B CA 1 ATOM 3660 C C . SER B 2 302 ? -0.947 4.423 -21.840 1.00 67.73 ? 302 SER B C 302 SER B C 1 ATOM 3661 O O . SER B 2 302 ? -0.052 4.780 -21.072 1.00 67.73 ? 302 SER B O 302 SER B O 1 ATOM 3662 C CB . SER B 2 302 ? -0.300 2.879 -23.695 1.00 67.73 ? 302 SER B CB 302 SER B CB 1 ATOM 3663 O OG . SER B 2 302 ? -1.193 1.955 -23.097 1.00 67.73 ? 302 SER B OG 302 SER B OG 1 ATOM 3664 N N . ALA B 2 303 ? -2.150 4.380 -21.448 1.00 73.30 ? 303 ALA B N 303 ALA B N 1 ATOM 3665 C CA . ALA B 2 303 ? -2.646 4.353 -20.075 1.00 73.30 ? 303 ALA B CA 303 ALA B CA 1 ATOM 3666 C C . ALA B 2 303 ? -2.379 3.000 -19.422 1.00 73.30 ? 303 ALA B C 303 ALA B C 1 ATOM 3667 O O . ALA B 2 303 ? -2.508 2.855 -18.204 1.00 73.30 ? 303 ALA B O 303 ALA B O 1 ATOM 3668 C CB . ALA B 2 303 ? -4.139 4.671 -20.042 1.00 73.30 ? 303 ALA B CB 303 ALA B CB 1 ATOM 3669 N N . ILE B 2 304 ? -1.851 2.049 -20.367 1.00 80.01 ? 304 ILE B N 304 ILE B N 1 ATOM 3670 C CA . ILE B 2 304 ? -1.593 0.709 -19.850 1.00 80.01 ? 304 ILE B CA 304 ILE B CA 1 ATOM 3671 C C . ILE B 2 304 ? -0.191 0.649 -19.247 1.00 80.01 ? 304 ILE B C 304 ILE B C 1 ATOM 3672 O O . ILE B 2 304 ? 0.790 1.003 -19.905 1.00 80.01 ? 304 ILE B O 304 ILE B O 1 ATOM 3673 C CB . ILE B 2 304 ? -1.748 -0.362 -20.954 1.00 80.01 ? 304 ILE B CB 304 ILE B CB 1 ATOM 3674 C CG1 . ILE B 2 304 ? -3.158 -0.310 -21.554 1.00 80.01 ? 304 ILE B CG1 304 ILE B CG1 1 ATOM 3675 C CG2 . ILE B 2 304 ? -1.439 -1.756 -20.400 1.00 80.01 ? 304 ILE B CG2 304 ILE B CG2 1 ATOM 3676 C CD1 . ILE B 2 304 ? -3.332 -1.168 -22.799 1.00 80.01 ? 304 ILE B CD1 304 ILE B CD1 1 ATOM 3677 N N . PRO B 2 305 ? -0.108 0.243 -17.996 1.00 81.10 ? 305 PRO B N 305 PRO B N 1 ATOM 3678 C CA . PRO B 2 305 ? 1.200 0.147 -17.345 1.00 81.10 ? 305 PRO B CA 305 PRO B CA 1 ATOM 3679 C C . PRO B 2 305 ? 2.162 -0.777 -18.088 1.00 81.10 ? 305 PRO B C 305 PRO B C 1 ATOM 3680 O O . PRO B 2 305 ? 1.797 -1.902 -18.439 1.00 81.10 ? 305 PRO B O 305 PRO B O 1 ATOM 3681 C CB . PRO B 2 305 ? 0.864 -0.414 -15.961 1.00 81.10 ? 305 PRO B CB 305 PRO B CB 1 ATOM 3682 C CG . PRO B 2 305 ? -0.598 -0.154 -15.788 1.00 81.10 ? 305 PRO B CG 305 PRO B CG 1 ATOM 3683 C CD . PRO B 2 305 ? -1.235 -0.089 -17.146 1.00 81.10 ? 305 PRO B CD 305 PRO B CD 1 ATOM 3684 N N . SER B 2 306 ? 3.251 -0.227 -18.552 1.00 83.88 ? 306 SER B N 306 SER B N 1 ATOM 3685 C CA . SER B 2 306 ? 4.310 -0.998 -19.194 1.00 83.88 ? 306 SER B CA 306 SER B CA 1 ATOM 3686 C C . SER B 2 306 ? 5.653 -0.770 -18.509 1.00 83.88 ? 306 SER B C 306 SER B C 1 ATOM 3687 O O . SER B 2 306 ? 5.895 0.300 -17.946 1.00 83.88 ? 306 SER B O 306 SER B O 1 ATOM 3688 C CB . SER B 2 306 ? 4.416 -0.634 -20.675 1.00 83.88 ? 306 SER B CB 306 SER B CB 1 ATOM 3689 O OG . SER B 2 306 ? 5.525 -1.283 -21.274 1.00 83.88 ? 306 SER B OG 306 SER B OG 1 ATOM 3690 N N . ASP B 2 307 ? 6.455 -1.859 -18.534 1.00 87.41 ? 307 ASP B N 307 ASP B N 1 ATOM 3691 C CA . ASP B 2 307 ? 7.777 -1.773 -17.921 1.00 87.41 ? 307 ASP B CA 307 ASP B CA 1 ATOM 3692 C C . ASP B 2 307 ? 8.749 -1.008 -18.817 1.00 87.41 ? 307 ASP B C 307 ASP B C 1 ATOM 3693 O O . ASP B 2 307 ? 9.891 -0.755 -18.428 1.00 87.41 ? 307 ASP B O 307 ASP B O 1 ATOM 3694 C CB . ASP B 2 307 ? 8.323 -3.171 -17.625 1.00 87.41 ? 307 ASP B CB 307 ASP B CB 1 ATOM 3695 C CG . ASP B 2 307 ? 7.545 -3.894 -16.540 1.00 87.41 ? 307 ASP B CG 307 ASP B CG 1 ATOM 3696 O OD1 . ASP B 2 307 ? 6.680 -3.269 -15.889 1.00 87.41 ? 307 ASP B OD1 307 ASP B OD1 1 ATOM 3697 O OD2 . ASP B 2 307 ? 7.800 -5.100 -16.333 1.00 87.41 ? 307 ASP B OD2 307 ASP B OD2 1 ATOM 3698 N N . ASP B 2 308 ? 8.308 -0.566 -19.984 1.00 86.51 ? 308 ASP B N 308 ASP B N 1 ATOM 3699 C CA . ASP B 2 308 ? 9.175 0.074 -20.969 1.00 86.51 ? 308 ASP B CA 308 ASP B CA 1 ATOM 3700 C C . ASP B 2 308 ? 9.273 1.577 -20.720 1.00 86.51 ? 308 ASP B C 308 ASP B C 1 ATOM 3701 O O . ASP B 2 308 ? 8.602 2.367 -21.387 1.00 86.51 ? 308 ASP B O 308 ASP B O 1 ATOM 3702 C CB . ASP B 2 308 ? 8.665 -0.192 -22.387 1.00 86.51 ? 308 ASP B CB 308 ASP B CB 1 ATOM 3703 C CG . ASP B 2 308 ? 9.670 0.189 -23.460 1.00 86.51 ? 308 ASP B CG 308 ASP B CG 1 ATOM 3704 O OD1 . ASP B 2 308 ? 10.841 0.470 -23.126 1.00 86.51 ? 308 ASP B OD1 308 ASP B OD1 1 ATOM 3705 O OD2 . ASP B 2 308 ? 9.286 0.210 -24.649 1.00 86.51 ? 308 ASP B OD2 308 ASP B OD2 1 ATOM 3706 N N . PHE B 2 309 ? 9.950 1.934 -19.617 1.00 89.22 ? 309 PHE B N 309 PHE B N 1 ATOM 3707 C CA . PHE B 2 309 ? 10.192 3.341 -19.320 1.00 89.22 ? 309 PHE B CA 309 PHE B CA 1 ATOM 3708 C C . PHE B 2 309 ? 11.532 3.524 -18.619 1.00 89.22 ? 309 PHE B C 309 PHE B C 1 ATOM 3709 O O . PHE B 2 309 ? 12.106 2.562 -18.105 1.00 89.22 ? 309 PHE B O 309 PHE B O 1 ATOM 3710 C CB . PHE B 2 309 ? 9.064 3.910 -18.454 1.00 89.22 ? 309 PHE B CB 309 PHE B CB 1 ATOM 3711 C CG . PHE B 2 309 ? 9.043 3.367 -17.051 1.00 89.22 ? 309 PHE B CG 309 PHE B CG 1 ATOM 3712 C CD1 . PHE B 2 309 ? 8.308 2.228 -16.742 1.00 89.22 ? 309 PHE B CD1 309 PHE B CD1 1 ATOM 3713 C CD2 . PHE B 2 309 ? 9.759 3.995 -16.040 1.00 89.22 ? 309 PHE B CD2 309 PHE B CD2 1 ATOM 3714 C CE1 . PHE B 2 309 ? 8.287 1.723 -15.444 1.00 89.22 ? 309 PHE B CE1 309 PHE B CE1 1 ATOM 3715 C CE2 . PHE B 2 309 ? 9.743 3.496 -14.740 1.00 89.22 ? 309 PHE B CE2 309 PHE B CE2 1 ATOM 3716 C CZ . PHE B 2 309 ? 9.006 2.361 -14.444 1.00 89.22 ? 309 PHE B CZ 309 PHE B CZ 1 ATOM 3717 N N . VAL B 2 310 ? 12.048 4.735 -18.739 1.00 90.58 ? 310 VAL B N 310 VAL B N 1 ATOM 3718 C CA . VAL B 2 310 ? 13.305 5.065 -18.076 1.00 90.58 ? 310 VAL B CA 310 VAL B CA 1 ATOM 3719 C C . VAL B 2 310 ? 13.060 6.117 -16.998 1.00 90.58 ? 310 VAL B C 310 VAL B C 1 ATOM 3720 O O . VAL B 2 310 ? 12.300 7.066 -17.208 1.00 90.58 ? 310 VAL B O 310 VAL B O 1 ATOM 3721 C CB . VAL B 2 310 ? 14.363 5.570 -19.083 1.00 90.58 ? 310 VAL B CB 310 VAL B CB 1 ATOM 3722 C CG1 . VAL B 2 310 ? 15.657 5.947 -18.364 1.00 90.58 ? 310 VAL B CG1 310 VAL B CG1 1 ATOM 3723 C CG2 . VAL B 2 310 ? 14.630 4.511 -20.151 1.00 90.58 ? 310 VAL B CG2 310 VAL B CG2 1 ATOM 3724 N N . VAL B 2 311 ? 13.626 5.894 -15.872 1.00 92.27 ? 311 VAL B N 311 VAL B N 1 ATOM 3725 C CA . VAL B 2 311 ? 13.492 6.813 -14.747 1.00 92.27 ? 311 VAL B CA 311 VAL B CA 1 ATOM 3726 C C . VAL B 2 311 ? 14.306 8.077 -15.012 1.00 92.27 ? 311 VAL B C 311 VAL B C 1 ATOM 3727 O O . VAL B 2 311 ? 15.496 8.003 -15.327 1.00 92.27 ? 311 VAL B O 311 VAL B O 1 ATOM 3728 C CB . VAL B 2 311 ? 13.942 6.157 -13.422 1.00 92.27 ? 311 VAL B CB 311 VAL B CB 1 ATOM 3729 C CG1 . VAL B 2 311 ? 13.804 7.139 -12.260 1.00 92.27 ? 311 VAL B CG1 311 VAL B CG1 1 ATOM 3730 C CG2 . VAL B 2 311 ? 13.134 4.889 -13.153 1.00 92.27 ? 311 VAL B CG2 311 VAL B CG2 1 ATOM 3731 N N . GLN B 2 312 ? 13.609 9.226 -14.890 1.00 90.75 ? 312 GLN B N 312 GLN B N 1 ATOM 3732 C CA . GLN B 2 312 ? 14.249 10.509 -15.160 1.00 90.75 ? 312 GLN B CA 312 GLN B CA 1 ATOM 3733 C C . GLN B 2 312 ? 14.364 11.345 -13.889 1.00 90.75 ? 312 GLN B C 312 GLN B C 1 ATOM 3734 O O . GLN B 2 312 ? 13.605 11.146 -12.938 1.00 90.75 ? 312 GLN B O 312 GLN B O 1 ATOM 3735 C CB . GLN B 2 312 ? 13.474 11.282 -16.229 1.00 90.75 ? 312 GLN B CB 312 GLN B CB 1 ATOM 3736 C CG . GLN B 2 312 ? 13.477 10.612 -17.596 1.00 90.75 ? 312 GLN B CG 312 GLN B CG 1 ATOM 3737 C CD . GLN B 2 312 ? 12.679 11.384 -18.630 1.00 90.75 ? 312 GLN B CD 312 GLN B CD 1 ATOM 3738 O OE1 . GLN B 2 312 ? 12.005 12.367 -18.305 1.00 90.75 ? 312 GLN B OE1 312 GLN B OE1 1 ATOM 3739 N NE2 . GLN B 2 312 ? 12.747 10.944 -19.882 1.00 90.75 ? 312 GLN B NE2 312 GLN B NE2 1 ATOM 3740 N N . SER B 2 313 ? 15.321 12.271 -13.989 1.00 89.40 ? 313 SER B N 313 SER B N 1 ATOM 3741 C CA . SER B 2 313 ? 15.483 13.192 -12.868 1.00 89.40 ? 313 SER B CA 313 SER B CA 1 ATOM 3742 C C . SER B 2 313 ? 14.326 14.182 -12.795 1.00 89.40 ? 313 SER B C 313 SER B C 1 ATOM 3743 O O . SER B 2 313 ? 13.649 14.428 -13.795 1.00 89.40 ? 313 SER B O 313 SER B O 1 ATOM 3744 C CB . SER B 2 313 ? 16.807 13.949 -12.983 1.00 89.40 ? 313 SER B CB 313 SER B CB 1 ATOM 3745 O OG . SER B 2 313 ? 16.837 14.733 -14.164 1.00 89.40 ? 313 SER B OG 313 SER B OG 1 ATOM 3746 N N . GLY B 2 314 ? 13.966 14.696 -11.570 1.00 89.11 ? 314 GLY B N 314 GLY B N 1 ATOM 3747 C CA . GLY B 2 314 ? 12.902 15.661 -11.343 1.00 89.11 ? 314 GLY B CA 314 GLY B CA 1 ATOM 3748 C C . GLY B 2 314 ? 11.542 15.017 -11.154 1.00 89.11 ? 314 GLY B C 314 GLY B C 1 ATOM 3749 O O . GLY B 2 314 ? 10.518 15.705 -11.155 1.00 89.11 ? 314 GLY B O 314 GLY B O 1 ATOM 3750 N N . GLU B 2 315 ? 11.540 13.675 -11.061 1.00 91.06 ? 315 GLU B N 315 GLU B N 1 ATOM 3751 C CA . GLU B 2 315 ? 10.297 12.931 -10.886 1.00 91.06 ? 315 GLU B CA 315 GLU B CA 1 ATOM 3752 C C . GLU B 2 315 ? 10.131 12.464 -9.443 1.00 91.06 ? 315 GLU B C 315 GLU B C 1 ATOM 3753 O O . GLU B 2 315 ? 11.114 12.326 -8.712 1.00 91.06 ? 315 GLU B O 315 GLU B O 1 ATOM 3754 C CB . GLU B 2 315 ? 10.250 11.731 -11.836 1.00 91.06 ? 315 GLU B CB 315 GLU B CB 1 ATOM 3755 C CG . GLU B 2 315 ? 10.281 12.111 -13.309 1.00 91.06 ? 315 GLU B CG 315 GLU B CG 1 ATOM 3756 C CD . GLU B 2 315 ? 10.389 10.911 -14.236 1.00 91.06 ? 315 GLU B CD 315 GLU B CD 1 ATOM 3757 O OE1 . GLU B 2 315 ? 10.123 11.056 -15.451 1.00 91.06 ? 315 GLU B OE1 315 GLU B OE1 1 ATOM 3758 O OE2 . GLU B 2 315 ? 10.742 9.816 -13.743 1.00 91.06 ? 315 GLU B OE2 315 GLU B OE2 1 ATOM 3759 N N . VAL B 2 316 ? 8.910 12.293 -9.076 1.00 92.77 ? 316 VAL B N 316 VAL B N 1 ATOM 3760 C CA . VAL B 2 316 ? 8.562 11.760 -7.763 1.00 92.77 ? 316 VAL B CA 316 VAL B CA 1 ATOM 3761 C C . VAL B 2 316 ? 7.974 10.359 -7.914 1.00 92.77 ? 316 VAL B C 316 VAL B C 1 ATOM 3762 O O . VAL B 2 316 ? 7.106 10.131 -8.761 1.00 92.77 ? 316 VAL B O 316 VAL B O 1 ATOM 3763 C CB . VAL B 2 316 ? 7.566 12.680 -7.022 1.00 92.77 ? 316 VAL B CB 316 VAL B CB 1 ATOM 3764 C CG1 . VAL B 2 316 ? 7.295 12.157 -5.613 1.00 92.77 ? 316 VAL B CG1 316 VAL B CG1 1 ATOM 3765 C CG2 . VAL B 2 316 ? 8.098 14.111 -6.972 1.00 92.77 ? 316 VAL B CG2 316 VAL B CG2 1 ATOM 3766 N N . TYR B 2 317 ? 8.425 9.430 -7.072 1.00 94.63 ? 317 TYR B N 317 TYR B N 1 ATOM 3767 C CA . TYR B 2 317 ? 7.987 8.043 -7.181 1.00 94.63 ? 317 TYR B CA 317 TYR B CA 1 ATOM 3768 C C . TYR B 2 317 ? 7.410 7.548 -5.861 1.00 94.63 ? 317 TYR B C 317 TYR B C 1 ATOM 3769 O O . TYR B 2 317 ? 7.877 7.936 -4.787 1.00 94.63 ? 317 TYR B O 317 TYR B O 1 ATOM 3770 C CB . TYR B 2 317 ? 9.149 7.144 -7.613 1.00 94.63 ? 317 TYR B CB 317 TYR B CB 1 ATOM 3771 C CG . TYR B 2 317 ? 9.432 7.187 -9.095 1.00 94.63 ? 317 TYR B CG 317 TYR B CG 1 ATOM 3772 C CD1 . TYR B 2 317 ? 8.901 6.226 -9.953 1.00 94.63 ? 317 TYR B CD1 317 TYR B CD1 1 ATOM 3773 C CD2 . TYR B 2 317 ? 10.231 8.186 -9.639 1.00 94.63 ? 317 TYR B CD2 317 TYR B CD2 1 ATOM 3774 C CE1 . TYR B 2 317 ? 9.161 6.261 -11.319 1.00 94.63 ? 317 TYR B CE1 317 TYR B CE1 1 ATOM 3775 C CE2 . TYR B 2 317 ? 10.498 8.230 -11.004 1.00 94.63 ? 317 TYR B CE2 317 TYR B CE2 1 ATOM 3776 C CZ . TYR B 2 317 ? 9.959 7.265 -11.835 1.00 94.63 ? 317 TYR B CZ 317 TYR B CZ 1 ATOM 3777 O OH . TYR B 2 317 ? 10.219 7.304 -13.186 1.00 94.63 ? 317 TYR B OH 317 TYR B OH 1 ATOM 3778 N N . LEU B 2 318 ? 6.380 6.750 -5.969 1.00 94.72 ? 318 LEU B N 318 LEU B N 1 ATOM 3779 C CA . LEU B 2 318 ? 5.841 5.961 -4.866 1.00 94.72 ? 318 LEU B CA 318 LEU B CA 1 ATOM 3780 C C . LEU B 2 318 ? 6.268 4.502 -4.983 1.00 94.72 ? 318 LEU B C 318 LEU B C 1 ATOM 3781 O O . LEU B 2 318 ? 5.972 3.842 -5.982 1.00 94.72 ? 318 LEU B O 318 LEU B O 1 ATOM 3782 C CB . LEU B 2 318 ? 4.313 6.057 -4.834 1.00 94.72 ? 318 LEU B CB 318 LEU B CB 1 ATOM 3783 C CG . LEU B 2 318 ? 3.603 5.209 -3.778 1.00 94.72 ? 318 LEU B CG 318 LEU B CG 1 ATOM 3784 C CD1 . LEU B 2 318 ? 3.832 5.792 -2.388 1.00 94.72 ? 318 LEU B CD1 318 LEU B CD1 1 ATOM 3785 C CD2 . LEU B 2 318 ? 2.112 5.112 -4.085 1.00 94.72 ? 318 LEU B CD2 318 LEU B CD2 1 ATOM 3786 N N . ILE B 2 319 ? 6.993 4.081 -4.066 1.00 96.77 ? 319 ILE B N 319 ILE B N 1 ATOM 3787 C CA . ILE B 2 319 ? 7.416 2.686 -4.008 1.00 96.77 ? 319 ILE B CA 319 ILE B CA 1 ATOM 3788 C C . ILE B 2 319 ? 6.563 1.931 -2.990 1.00 96.77 ? 319 ILE B C 319 ILE B C 1 ATOM 3789 O O . ILE B 2 319 ? 6.703 2.133 -1.782 1.00 96.77 ? 319 ILE B O 319 ILE B O 1 ATOM 3790 C CB . ILE B 2 319 ? 8.913 2.563 -3.649 1.00 96.77 ? 319 ILE B CB 319 ILE B CB 1 ATOM 3791 C CG1 . ILE B 2 319 ? 9.760 3.437 -4.581 1.00 96.77 ? 319 ILE B CG1 319 ILE B CG1 1 ATOM 3792 C CG2 . ILE B 2 319 ? 9.365 1.101 -3.709 1.00 96.77 ? 319 ILE B CG2 319 ILE B CG2 1 ATOM 3793 C CD1 . ILE B 2 319 ? 11.193 3.638 -4.110 1.00 96.77 ? 319 ILE B CD1 319 ILE B CD1 1 ATOM 3794 N N . ASP B 2 320 ? 5.746 1.033 -3.419 1.00 96.14 ? 320 ASP B N 320 ASP B N 1 ATOM 3795 C CA . ASP B 2 320 ? 4.858 0.224 -2.589 1.00 96.14 ? 320 ASP B CA 320 ASP B CA 1 ATOM 3796 C C . ASP B 2 320 ? 5.044 -1.264 -2.875 1.00 96.14 ? 320 ASP B C 320 ASP B C 1 ATOM 3797 O O . ASP B 2 320 ? 4.539 -1.778 -3.875 1.00 96.14 ? 320 ASP B O 320 ASP B O 1 ATOM 3798 C CB . ASP B 2 320 ? 3.399 0.625 -2.816 1.00 96.14 ? 320 ASP B CB 320 ASP B CB 1 ATOM 3799 C CG . ASP B 2 320 ? 2.446 -0.019 -1.824 1.00 96.14 ? 320 ASP B CG 320 ASP B CG 1 ATOM 3800 O OD1 . ASP B 2 320 ? 2.904 -0.779 -0.943 1.00 96.14 ? 320 ASP B OD1 320 ASP B OD1 1 ATOM 3801 O OD2 . ASP B 2 320 ? 1.226 0.233 -1.926 1.00 96.14 ? 320 ASP B OD2 320 ASP B OD2 1 ATOM 3802 N N . LEU B 2 321 ? 5.711 -1.885 -1.962 1.00 97.99 ? 321 LEU B N 321 LEU B N 1 ATOM 3803 C CA . LEU B 2 321 ? 6.044 -3.289 -2.176 1.00 97.99 ? 321 LEU B CA 321 LEU B CA 1 ATOM 3804 C C . LEU B 2 321 ? 5.445 -4.163 -1.078 1.00 97.99 ? 321 LEU B C 321 LEU B C 1 ATOM 3805 O O . LEU B 2 321 ? 5.670 -3.917 0.109 1.00 97.99 ? 321 LEU B O 321 LEU B O 1 ATOM 3806 C CB . LEU B 2 321 ? 7.562 -3.479 -2.224 1.00 97.99 ? 321 LEU B CB 321 LEU B CB 1 ATOM 3807 C CG . LEU B 2 321 ? 8.301 -2.746 -3.345 1.00 97.99 ? 321 LEU B CG 321 LEU B CG 1 ATOM 3808 C CD1 . LEU B 2 321 ? 9.806 -2.957 -3.213 1.00 97.99 ? 321 LEU B CD1 321 LEU B CD1 1 ATOM 3809 C CD2 . LEU B 2 321 ? 7.808 -3.218 -4.709 1.00 97.99 ? 321 LEU B CD2 321 LEU B CD2 1 ATOM 3810 N N . LYS B 2 322 ? 4.686 -5.155 -1.516 1.00 97.76 ? 322 LYS B N 322 LYS B N 1 ATOM 3811 C CA . LYS B 2 322 ? 4.095 -6.148 -0.623 1.00 97.76 ? 322 LYS B CA 322 LYS B CA 1 ATOM 3812 C C . LYS B 2 322 ? 4.646 -7.542 -0.908 1.00 97.76 ? 322 LYS B C 322 LYS B C 1 ATOM 3813 O O . LYS B 2 322 ? 4.662 -7.985 -2.058 1.00 97.76 ? 322 LYS B O 322 LYS B O 1 ATOM 3814 C CB . LYS B 2 322 ? 2.572 -6.149 -0.755 1.00 97.76 ? 322 LYS B CB 322 LYS B CB 1 ATOM 3815 C CG . LYS B 2 322 ? 1.927 -4.793 -0.506 1.00 97.76 ? 322 LYS B CG 322 LYS B CG 1 ATOM 3816 C CD . LYS B 2 322 ? 0.434 -4.821 -0.806 1.00 97.76 ? 322 LYS B CD 322 LYS B CD 1 ATOM 3817 C CE . LYS B 2 322 ? -0.189 -3.438 -0.675 1.00 97.76 ? 322 LYS B CE 322 LYS B CE 1 ATOM 3818 N NZ . LYS B 2 322 ? -1.645 -3.452 -1.009 1.00 97.76 ? 322 LYS B NZ 322 LYS B NZ 1 ATOM 3819 N N . MET B 2 323 ? 5.092 -8.169 0.202 1.00 97.79 ? 323 MET B N 323 MET B N 1 ATOM 3820 C CA . MET B 2 323 ? 5.669 -9.503 0.066 1.00 97.79 ? 323 MET B CA 323 MET B CA 1 ATOM 3821 C C . MET B 2 323 ? 4.951 -10.502 0.967 1.00 97.79 ? 323 MET B C 323 MET B C 1 ATOM 3822 O O . MET B 2 323 ? 4.532 -10.156 2.073 1.00 97.79 ? 323 MET B O 323 MET B O 1 ATOM 3823 C CB . MET B 2 323 ? 7.163 -9.479 0.398 1.00 97.79 ? 323 MET B CB 323 MET B CB 1 ATOM 3824 C CG . MET B 2 323 ? 7.972 -8.546 -0.488 1.00 97.79 ? 323 MET B CG 323 MET B CG 1 ATOM 3825 S SD . MET B 2 323 ? 8.202 -9.210 -2.183 1.00 97.79 ? 323 MET B SD 323 MET B SD 1 ATOM 3826 C CE . MET B 2 323 ? 9.336 -7.967 -2.862 1.00 97.79 ? 323 MET B CE 323 MET B CE 1 ATOM 3827 N N . ALA B 2 324 ? 4.724 -11.695 0.380 1.00 97.01 ? 324 ALA B N 324 ALA B N 1 ATOM 3828 C CA . ALA B 2 324 ? 4.084 -12.758 1.151 1.00 97.01 ? 324 ALA B CA 324 ALA B CA 1 ATOM 3829 C C . ALA B 2 324 ? 4.947 -14.016 1.173 1.00 97.01 ? 324 ALA B C 324 ALA B C 1 ATOM 3830 O O . ALA B 2 324 ? 5.501 -14.414 0.145 1.00 97.01 ? 324 ALA B O 324 ALA B O 1 ATOM 3831 C CB . ALA B 2 324 ? 2.704 -13.073 0.579 1.00 97.01 ? 324 ALA B CB 324 ALA B CB 1 ATOM 3832 N N . SER B 2 325 ? 5.017 -14.639 2.320 1.00 94.30 ? 325 SER B N 325 SER B N 1 ATOM 3833 C CA . SER B 2 325 ? 5.822 -15.845 2.482 1.00 94.30 ? 325 SER B CA 325 SER B CA 1 ATOM 3834 C C . SER B 2 325 ? 5.125 -17.060 1.880 1.00 94.30 ? 325 SER B C 325 SER B C 1 ATOM 3835 O O . SER B 2 325 ? 3.916 -17.236 2.048 1.00 94.30 ? 325 SER B O 325 SER B O 1 ATOM 3836 C CB . SER B 2 325 ? 6.118 -16.098 3.961 1.00 94.30 ? 325 SER B CB 325 SER B CB 1 ATOM 3837 O OG . SER B 2 325 ? 6.825 -17.314 4.132 1.00 94.30 ? 325 SER B OG 325 SER B OG 1 ATOM 3838 N N . LEU B 2 326 ? 5.929 -17.899 1.216 1.00 93.05 ? 326 LEU B N 326 LEU B N 1 ATOM 3839 C CA . LEU B 2 326 ? 5.419 -19.127 0.616 1.00 93.05 ? 326 LEU B CA 326 LEU B CA 1 ATOM 3840 C C . LEU B 2 326 ? 5.910 -20.351 1.381 1.00 93.05 ? 326 LEU B C 326 LEU B C 1 ATOM 3841 O O . LEU B 2 326 ? 5.933 -21.459 0.839 1.00 93.05 ? 326 LEU B O 326 LEU B O 1 ATOM 3842 C CB . LEU B 2 326 ? 5.844 -19.222 -0.852 1.00 93.05 ? 326 LEU B CB 326 LEU B CB 1 ATOM 3843 C CG . LEU B 2 326 ? 5.390 -18.083 -1.765 1.00 93.05 ? 326 LEU B CG 326 LEU B CG 1 ATOM 3844 C CD1 . LEU B 2 326 ? 5.980 -18.255 -3.161 1.00 93.05 ? 326 LEU B CD1 326 LEU B CD1 1 ATOM 3845 C CD2 . LEU B 2 326 ? 3.868 -18.021 -1.827 1.00 93.05 ? 326 LEU B CD2 326 LEU B CD2 1 ATOM 3846 N N . GLU B 2 327 ? 6.290 -20.162 2.603 1.00 90.76 ? 327 GLU B N 327 GLU B N 1 ATOM 3847 C CA . GLU B 2 327 ? 6.868 -21.220 3.427 1.00 90.76 ? 327 GLU B CA 327 GLU B CA 1 ATOM 3848 C C . GLU B 2 327 ? 5.910 -22.401 3.559 1.00 90.76 ? 327 GLU B C 327 GLU B C 1 ATOM 3849 O O . GLU B 2 327 ? 6.324 -23.557 3.450 1.00 90.76 ? 327 GLU B O 327 GLU B O 1 ATOM 3850 C CB . GLU B 2 327 ? 7.234 -20.683 4.813 1.00 90.76 ? 327 GLU B CB 327 GLU B CB 1 ATOM 3851 C CG . GLU B 2 327 ? 7.889 -21.716 5.719 1.00 90.76 ? 327 GLU B CG 327 GLU B CG 1 ATOM 3852 C CD . GLU B 2 327 ? 8.261 -21.165 7.086 1.00 90.76 ? 327 GLU B CD 327 GLU B CD 1 ATOM 3853 O OE1 . GLU B 2 327 ? 8.734 -21.942 7.946 1.00 90.76 ? 327 GLU B OE1 327 GLU B OE1 1 ATOM 3854 O OE2 . GLU B 2 327 ? 8.076 -19.946 7.300 1.00 90.76 ? 327 GLU B OE2 327 GLU B OE2 1 ATOM 3855 N N . HIS B 2 328 ? 4.622 -22.159 3.750 1.00 87.79 ? 328 HIS B N 328 HIS B N 1 ATOM 3856 C CA . HIS B 2 328 ? 3.647 -23.209 4.022 1.00 87.79 ? 328 HIS B CA 328 HIS B CA 1 ATOM 3857 C C . HIS B 2 328 ? 2.971 -23.680 2.738 1.00 87.79 ? 328 HIS B C 328 HIS B C 1 ATOM 3858 O O . HIS B 2 328 ? 1.995 -24.431 2.785 1.00 87.79 ? 328 HIS B O 328 HIS B O 1 ATOM 3859 C CB . HIS B 2 328 ? 2.595 -22.719 5.019 1.00 87.79 ? 328 HIS B CB 328 HIS B CB 1 ATOM 3860 C CG . HIS B 2 328 ? 3.168 -22.289 6.332 1.00 87.79 ? 328 HIS B CG 328 HIS B CG 1 ATOM 3861 N ND1 . HIS B 2 328 ? 3.859 -23.148 7.160 1.00 87.79 ? 328 HIS B ND1 328 HIS B ND1 1 ATOM 3862 C CD2 . HIS B 2 328 ? 3.154 -21.089 6.959 1.00 87.79 ? 328 HIS B CD2 328 HIS B CD2 1 ATOM 3863 C CE1 . HIS B 2 328 ? 4.245 -22.493 8.241 1.00 87.79 ? 328 HIS B CE1 328 HIS B CE1 1 ATOM 3864 N NE2 . HIS B 2 328 ? 3.830 -21.241 8.144 1.00 87.79 ? 328 HIS B NE2 328 HIS B NE2 1 ATOM 3865 N N . CYS B 2 329 ? 3.528 -23.258 1.608 1.00 88.18 ? 329 CYS B N 329 CYS B N 1 ATOM 3866 C CA . CYS B 2 329 ? 2.990 -23.683 0.320 1.00 88.18 ? 329 CYS B CA 329 CYS B CA 1 ATOM 3867 C C . CYS B 2 329 ? 3.824 -24.811 -0.274 1.00 88.18 ? 329 CYS B C 329 CYS B C 1 ATOM 3868 O O . CYS B 2 329 ? 5.024 -24.649 -0.502 1.00 88.18 ? 329 CYS B O 329 CYS B O 1 ATOM 3869 C CB . CYS B 2 329 ? 2.941 -22.506 -0.654 1.00 88.18 ? 329 CYS B CB 329 CYS B CB 1 ATOM 3870 S SG . CYS B 2 329 ? 2.005 -21.089 -0.038 1.00 88.18 ? 329 CYS B SG 329 CYS B SG 1 ATOM 3871 N N . THR B 2 330 ? 3.272 -25.975 -0.484 1.00 82.95 ? 330 THR B N 330 THR B N 1 ATOM 3872 C CA . THR B 2 330 ? 3.994 -27.175 -0.893 1.00 82.95 ? 330 THR B CA 330 THR B CA 1 ATOM 3873 C C . THR B 2 330 ? 4.159 -27.216 -2.409 1.00 82.95 ? 330 THR B C 330 THR B C 1 ATOM 3874 O O . THR B 2 330 ? 5.163 -27.721 -2.916 1.00 82.95 ? 330 THR B O 330 THR B O 1 ATOM 3875 C CB . THR B 2 330 ? 3.274 -28.450 -0.417 1.00 82.95 ? 330 THR B CB 330 THR B CB 1 ATOM 3876 O OG1 . THR B 2 330 ? 1.914 -28.419 -0.866 1.00 82.95 ? 330 THR B OG1 330 THR B OG1 1 ATOM 3877 C CG2 . THR B 2 330 ? 3.293 -28.558 1.104 1.00 82.95 ? 330 THR B CG2 330 THR B CG2 1 ATOM 3878 N N . LYS B 2 331 ? 3.236 -26.553 -3.116 1.00 84.53 ? 331 LYS B N 331 LYS B N 1 ATOM 3879 C CA . LYS B 2 331 ? 3.221 -26.580 -4.575 1.00 84.53 ? 331 LYS B CA 331 LYS B CA 1 ATOM 3880 C C . LYS B 2 331 ? 3.367 -25.175 -5.153 1.00 84.53 ? 331 LYS B C 331 LYS B C 1 ATOM 3881 O O . LYS B 2 331 ? 3.319 -24.187 -4.416 1.00 84.53 ? 331 LYS B O 331 LYS B O 1 ATOM 3882 C CB . LYS B 2 331 ? 1.933 -27.226 -5.088 1.00 84.53 ? 331 LYS B CB 331 LYS B CB 1 ATOM 3883 C CG . LYS B 2 331 ? 1.737 -28.664 -4.630 1.00 84.53 ? 331 LYS B CG 331 LYS B CG 1 ATOM 3884 C CD . LYS B 2 331 ? 0.425 -29.241 -5.145 1.00 84.53 ? 331 LYS B CD 331 LYS B CD 1 ATOM 3885 C CE . LYS B 2 331 ? 0.213 -30.669 -4.662 1.00 84.53 ? 331 LYS B CE 331 LYS B CE 1 ATOM 3886 N NZ . LYS B 2 331 ? -1.076 -31.236 -5.158 1.00 84.53 ? 331 LYS B NZ 331 LYS B NZ 1 ATOM 3887 N N . LYS B 2 332 ? 3.639 -25.195 -6.443 1.00 86.86 ? 332 LYS B N 332 LYS B N 1 ATOM 3888 C CA . LYS B 2 332 ? 3.639 -23.914 -7.143 1.00 86.86 ? 332 LYS B CA 332 LYS B CA 1 ATOM 3889 C C . LYS B 2 332 ? 2.218 -23.386 -7.322 1.00 86.86 ? 332 LYS B C 332 LYS B C 1 ATOM 3890 O O . LYS B 2 332 ? 1.313 -24.137 -7.693 1.00 86.86 ? 332 LYS B O 332 LYS B O 1 ATOM 3891 C CB . LYS B 2 332 ? 4.323 -24.046 -8.504 1.00 86.86 ? 332 LYS B CB 332 LYS B CB 1 ATOM 3892 C CG . LYS B 2 332 ? 4.697 -22.715 -9.140 1.00 86.86 ? 332 LYS B CG 332 LYS B CG 1 ATOM 3893 C CD . LYS B 2 332 ? 5.564 -22.911 -10.377 1.00 86.86 ? 332 LYS B CD 332 LYS B CD 1 ATOM 3894 C CE . LYS B 2 332 ? 5.913 -21.581 -11.033 1.00 86.86 ? 332 LYS B CE 332 LYS B CE 1 ATOM 3895 N NZ . LYS B 2 332 ? 6.837 -21.761 -12.192 1.00 86.86 ? 332 LYS B NZ 332 LYS B NZ 1 ATOM 3896 N N . GLY B 2 333 ? 2.067 -22.156 -6.966 1.00 90.76 ? 333 GLY B N 333 GLY B N 1 ATOM 3897 C CA . GLY B 2 333 ? 0.723 -21.608 -7.053 1.00 90.76 ? 333 GLY B CA 333 GLY B CA 1 ATOM 3898 C C . GLY B 2 333 ? 0.703 -20.112 -7.307 1.00 90.76 ? 333 GLY B C 333 GLY B C 1 ATOM 3899 O O . GLY B 2 333 ? 1.756 -19.491 -7.468 1.00 90.76 ? 333 GLY B O 333 GLY B O 1 ATOM 3900 N N . LEU B 2 334 ? -0.482 -19.612 -7.411 1.00 94.09 ? 334 LEU B N 334 LEU B N 1 ATOM 3901 C CA . LEU B 2 334 ? -0.749 -18.209 -7.708 1.00 94.09 ? 334 LEU B CA 334 LEU B CA 1 ATOM 3902 C C . LEU B 2 334 ? -1.062 -17.433 -6.433 1.00 94.09 ? 334 LEU B C 334 LEU B C 1 ATOM 3903 O O . LEU B 2 334 ? -1.895 -17.860 -5.630 1.00 94.09 ? 334 LEU B O 334 LEU B O 1 ATOM 3904 C CB . LEU B 2 334 ? -1.912 -18.081 -8.695 1.00 94.09 ? 334 LEU B CB 334 LEU B CB 1 ATOM 3905 C CG . LEU B 2 334 ? -2.354 -16.659 -9.043 1.00 94.09 ? 334 LEU B CG 334 LEU B CG 1 ATOM 3906 C CD1 . LEU B 2 334 ? -1.345 -16.005 -9.981 1.00 94.09 ? 334 LEU B CD1 334 LEU B CD1 1 ATOM 3907 C CD2 . LEU B 2 334 ? -3.745 -16.668 -9.668 1.00 94.09 ? 334 LEU B CD2 334 LEU B CD2 1 ATOM 3908 N N . VAL B 2 335 ? -0.312 -16.392 -6.195 1.00 95.32 ? 335 VAL B N 335 VAL B N 1 ATOM 3909 C CA . VAL B 2 335 ? -0.646 -15.451 -5.131 1.00 95.32 ? 335 VAL B CA 335 VAL B CA 1 ATOM 3910 C C . VAL B 2 335 ? -1.650 -14.422 -5.648 1.00 95.32 ? 335 VAL B C 335 VAL B C 1 ATOM 3911 O O . VAL B 2 335 ? -1.377 -13.712 -6.618 1.00 95.32 ? 335 VAL B O 335 VAL B O 1 ATOM 3912 C CB . VAL B 2 335 ? 0.612 -14.740 -4.585 1.00 95.32 ? 335 VAL B CB 335 VAL B CB 1 ATOM 3913 C CG1 . VAL B 2 335 ? 0.237 -13.745 -3.489 1.00 95.32 ? 335 VAL B CG1 335 VAL B CG1 1 ATOM 3914 C CG2 . VAL B 2 335 ? 1.617 -15.764 -4.061 1.00 95.32 ? 335 VAL B CG2 335 VAL B CG2 1 ATOM 3915 N N . THR B 2 336 ? -2.837 -14.380 -5.042 1.00 94.26 ? 336 THR B N 336 THR B N 1 ATOM 3916 C CA . THR B 2 336 ? -3.892 -13.482 -5.498 1.00 94.26 ? 336 THR B CA 336 THR B CA 1 ATOM 3917 C C . THR B 2 336 ? -4.570 -12.799 -4.314 1.00 94.26 ? 336 THR B C 336 THR B C 1 ATOM 3918 O O . THR B 2 336 ? -4.291 -13.126 -3.158 1.00 94.26 ? 336 THR B O 336 THR B O 1 ATOM 3919 C CB . THR B 2 336 ? -4.945 -14.234 -6.332 1.00 94.26 ? 336 THR B CB 336 THR B CB 1 ATOM 3920 O OG1 . THR B 2 336 ? -5.853 -13.288 -6.910 1.00 94.26 ? 336 THR B OG1 336 THR B OG1 1 ATOM 3921 C CG2 . THR B 2 336 ? -5.732 -15.215 -5.469 1.00 94.26 ? 336 THR B CG2 336 THR B CG2 1 ATOM 3922 N N . LEU B 2 337 ? -5.406 -11.748 -4.615 1.00 93.09 ? 337 LEU B N 337 LEU B N 1 ATOM 3923 C CA . LEU B 2 337 ? -6.116 -10.981 -3.598 1.00 93.09 ? 337 LEU B CA 337 LEU B CA 1 ATOM 3924 C C . LEU B 2 337 ? -7.611 -11.279 -3.637 1.00 93.09 ? 337 LEU B C 337 LEU B C 1 ATOM 3925 O O . LEU B 2 337 ? -8.224 -11.262 -4.707 1.00 93.09 ? 337 LEU B O 337 LEU B O 1 ATOM 3926 C CB . LEU B 2 337 ? -5.878 -9.481 -3.794 1.00 93.09 ? 337 LEU B CB 337 LEU B CB 1 ATOM 3927 C CG . LEU B 2 337 ? -4.428 -9.005 -3.686 1.00 93.09 ? 337 LEU B CG 337 LEU B CG 1 ATOM 3928 C CD1 . LEU B 2 337 ? -4.314 -7.550 -4.127 1.00 93.09 ? 337 LEU B CD1 337 LEU B CD1 1 ATOM 3929 C CD2 . LEU B 2 337 ? -3.912 -9.180 -2.261 1.00 93.09 ? 337 LEU B CD2 337 LEU B CD2 1 ATOM 3930 N N . GLU B 2 338 ? -8.087 -11.655 -2.486 1.00 91.75 ? 338 GLU B N 338 GLU B N 1 ATOM 3931 C CA . GLU B 2 338 ? -9.525 -11.853 -2.330 1.00 91.75 ? 338 GLU B CA 338 GLU B CA 1 ATOM 3932 C C . GLU B 2 338 ? -10.183 -10.640 -1.680 1.00 91.75 ? 338 GLU B C 338 GLU B C 1 ATOM 3933 O O . GLU B 2 338 ? -9.718 -10.154 -0.647 1.00 91.75 ? 338 GLU B O 338 GLU B O 1 ATOM 3934 C CB . GLU B 2 338 ? -9.808 -13.111 -1.504 1.00 91.75 ? 338 GLU B CB 338 GLU B CB 1 ATOM 3935 C CG . GLU B 2 338 ? -11.289 -13.397 -1.306 1.00 91.75 ? 338 GLU B CG 338 GLU B CG 1 ATOM 3936 C CD . GLU B 2 338 ? -11.555 -14.554 -0.357 1.00 91.75 ? 338 GLU B CD 338 GLU B CD 1 ATOM 3937 O OE1 . GLU B 2 338 ? -12.740 -14.865 -0.096 1.00 91.75 ? 338 GLU B OE1 338 GLU B OE1 1 ATOM 3938 O OE2 . GLU B 2 338 ? -10.572 -15.154 0.130 1.00 91.75 ? 338 GLU B OE2 338 GLU B OE2 1 ATOM 3939 N N . THR B 2 339 ? -11.275 -10.150 -2.314 1.00 90.60 ? 339 THR B N 339 THR B N 1 ATOM 3940 C CA . THR B 2 339 ? -12.032 -9.044 -1.740 1.00 90.60 ? 339 THR B CA 339 THR B CA 1 ATOM 3941 C C . THR B 2 339 ? -13.004 -9.547 -0.677 1.00 90.60 ? 339 THR B C 339 THR B C 1 ATOM 3942 O O . THR B 2 339 ? -13.772 -10.480 -0.922 1.00 90.60 ? 339 THR B O 339 THR B O 1 ATOM 3943 C CB . THR B 2 339 ? -12.808 -8.274 -2.825 1.00 90.60 ? 339 THR B CB 339 THR B CB 1 ATOM 3944 O OG1 . THR B 2 339 ? -11.889 -7.813 -3.824 1.00 90.60 ? 339 THR B OG1 339 THR B OG1 1 ATOM 3945 C CG2 . THR B 2 339 ? -13.541 -7.075 -2.232 1.00 90.60 ? 339 THR B CG2 339 THR B CG2 1 ATOM 3946 N N . VAL B 2 340 ? -12.944 -8.940 0.512 1.00 89.70 ? 340 VAL B N 340 VAL B N 1 ATOM 3947 C CA . VAL B 2 340 ? -13.763 -9.355 1.647 1.00 89.70 ? 340 VAL B CA 340 VAL B CA 1 ATOM 3948 C C . VAL B 2 340 ? -15.208 -8.913 1.431 1.00 89.70 ? 340 VAL B C 340 VAL B C 1 ATOM 3949 O O . VAL B 2 340 ? -15.462 -7.777 1.023 1.00 89.70 ? 340 VAL B O 340 VAL B O 1 ATOM 3950 C CB . VAL B 2 340 ? -13.223 -8.781 2.976 1.00 89.70 ? 340 VAL B CB 340 VAL B CB 1 ATOM 3951 C CG1 . VAL B 2 340 ? -14.158 -9.126 4.133 1.00 89.70 ? 340 VAL B CG1 340 VAL B CG1 1 ATOM 3952 C CG2 . VAL B 2 340 ? -11.814 -9.305 3.249 1.00 89.70 ? 340 VAL B CG2 340 VAL B CG2 1 ATOM 3953 N N . ASP B 2 341 ? -16.077 -9.814 1.733 1.00 85.24 ? 341 ASP B N 341 ASP B N 1 ATOM 3954 C CA . ASP B 2 341 ? -17.503 -9.527 1.616 1.00 85.24 ? 341 ASP B CA 341 ASP B CA 1 ATOM 3955 C C . ASP B 2 341 ? -17.982 -8.645 2.767 1.00 85.24 ? 341 ASP B C 341 ASP B C 1 ATOM 3956 O O . ASP B 2 341 ? -17.494 -8.764 3.892 1.00 85.24 ? 341 ASP B O 341 ASP B O 1 ATOM 3957 C CB . ASP B 2 341 ? -18.311 -10.826 1.577 1.00 85.24 ? 341 ASP B CB 341 ASP B CB 1 ATOM 3958 C CG . ASP B 2 341 ? -18.095 -11.620 0.301 1.00 85.24 ? 341 ASP B CG 341 ASP B CG 1 ATOM 3959 O OD1 . ASP B 2 341 ? -17.703 -11.028 -0.727 1.00 85.24 ? 341 ASP B OD1 341 ASP B OD1 1 ATOM 3960 O OD2 . ASP B 2 341 ? -18.322 -12.849 0.324 1.00 85.24 ? 341 ASP B OD2 341 ASP B OD2 1 ATOM 3961 N N . SER B 2 342 ? -18.987 -7.722 2.420 1.00 82.68 ? 342 SER B N 342 SER B N 1 ATOM 3962 C CA . SER B 2 342 ? -19.512 -6.781 3.404 1.00 82.68 ? 342 SER B CA 342 SER B CA 1 ATOM 3963 C C . SER B 2 342 ? -20.776 -7.321 4.065 1.00 82.68 ? 342 SER B C 342 SER B C 1 ATOM 3964 O O . SER B 2 342 ? -21.151 -6.877 5.152 1.00 82.68 ? 342 SER B O 342 SER B O 1 ATOM 3965 C CB . SER B 2 342 ? -19.806 -5.430 2.750 1.00 82.68 ? 342 SER B CB 342 SER B CB 1 ATOM 3966 O OG . SER B 2 342 ? -20.683 -5.585 1.647 1.00 82.68 ? 342 SER B OG 342 SER B OG 1 ATOM 3967 N N . TYR B 2 343 ? -21.429 -8.293 3.503 1.00 79.29 ? 343 TYR B N 343 TYR B N 1 ATOM 3968 C CA . TYR B 2 343 ? -22.724 -8.758 3.987 1.00 79.29 ? 343 TYR B CA 343 TYR B CA 1 ATOM 3969 C C . TYR B 2 343 ? -22.630 -10.186 4.511 1.00 79.29 ? 343 TYR B C 343 TYR B C 1 ATOM 3970 O O . TYR B 2 343 ? -21.926 -11.020 3.936 1.00 79.29 ? 343 TYR B O 343 TYR B O 1 ATOM 3971 C CB . TYR B 2 343 ? -23.774 -8.678 2.875 1.00 79.29 ? 343 TYR B CB 343 TYR B CB 1 ATOM 3972 C CG . TYR B 2 343 ? -23.994 -7.282 2.346 1.00 79.29 ? 343 TYR B CG 343 TYR B CG 1 ATOM 3973 C CD1 . TYR B 2 343 ? -24.787 -6.370 3.039 1.00 79.29 ? 343 TYR B CD1 343 TYR B CD1 1 ATOM 3974 C CD2 . TYR B 2 343 ? -23.409 -6.871 1.153 1.00 79.29 ? 343 TYR B CD2 343 TYR B CD2 1 ATOM 3975 C CE1 . TYR B 2 343 ? -24.994 -5.083 2.555 1.00 79.29 ? 343 TYR B CE1 343 TYR B CE1 1 ATOM 3976 C CE2 . TYR B 2 343 ? -23.609 -5.586 0.659 1.00 79.29 ? 343 TYR B CE2 343 TYR B CE2 1 ATOM 3977 C CZ . TYR B 2 343 ? -24.401 -4.700 1.366 1.00 79.29 ? 343 TYR B CZ 343 TYR B CZ 1 ATOM 3978 O OH . TYR B 2 343 ? -24.602 -3.427 0.882 1.00 79.29 ? 343 TYR B OH 343 TYR B OH 1 ATOM 3979 N N . THR B 2 344 ? -23.325 -10.330 5.635 1.00 67.47 ? 344 THR B N 344 THR B N 1 ATOM 3980 C CA . THR B 2 344 ? -23.461 -11.643 6.255 1.00 67.47 ? 344 THR B CA 344 THR B CA 1 ATOM 3981 C C . THR B 2 344 ? -24.469 -12.499 5.492 1.00 67.47 ? 344 THR B C 344 THR B C 1 ATOM 3982 O O . THR B 2 344 ? -25.417 -11.975 4.905 1.00 67.47 ? 344 THR B O 344 THR B O 1 ATOM 3983 C CB . THR B 2 344 ? -23.895 -11.524 7.727 1.00 67.47 ? 344 THR B CB 344 THR B CB 1 ATOM 3984 O OG1 . THR B 2 344 ? -25.207 -10.952 7.788 1.00 67.47 ? 344 THR B OG1 344 THR B OG1 1 ATOM 3985 C CG2 . THR B 2 344 ? -22.932 -10.642 8.515 1.00 67.47 ? 344 THR B CG2 344 THR B CG2 1 ATOM 3986 N N . GLY B 2 345 ? -24.101 -13.808 5.115 1.00 61.45 ? 345 GLY B N 345 GLY B N 1 ATOM 3987 C CA . GLY B 2 345 ? -25.053 -14.736 4.526 1.00 61.45 ? 345 GLY B CA 345 GLY B CA 1 ATOM 3988 C C . GLY B 2 345 ? -24.711 -15.116 3.098 1.00 61.45 ? 345 GLY B C 345 GLY B C 1 ATOM 3989 O O . GLY B 2 345 ? -25.314 -16.030 2.531 1.00 61.45 ? 345 GLY B O 345 GLY B O 1 ATOM 3990 N N . LYS B 2 346 ? -23.850 -14.201 2.517 1.00 61.80 ? 346 LYS B N 346 LYS B N 1 ATOM 3991 C CA . LYS B 2 346 ? -23.490 -14.481 1.130 1.00 61.80 ? 346 LYS B CA 346 LYS B CA 1 ATOM 3992 C C . LYS B 2 346 ? -22.468 -15.611 1.045 1.00 61.80 ? 346 LYS B C 346 LYS B C 1 ATOM 3993 O O . LYS B 2 346 ? -22.455 -16.372 0.075 1.00 61.80 ? 346 LYS B O 346 LYS B O 1 ATOM 3994 C CB . LYS B 2 346 ? -22.940 -13.225 0.454 1.00 61.80 ? 346 LYS B CB 346 LYS B CB 1 ATOM 3995 C CG . LYS B 2 346 ? -23.981 -12.138 0.225 1.00 61.80 ? 346 LYS B CG 346 LYS B CG 1 ATOM 3996 C CD . LYS B 2 346 ? -23.409 -10.975 -0.574 1.00 61.80 ? 346 LYS B CD 346 LYS B CD 1 ATOM 3997 C CE . LYS B 2 346 ? -24.445 -9.880 -0.789 1.00 61.80 ? 346 LYS B CE 346 LYS B CE 1 ATOM 3998 N NZ . LYS B 2 346 ? -23.890 -8.740 -1.579 1.00 61.80 ? 346 LYS B NZ 346 LYS B NZ 1 ATOM 3999 N N . SER B 2 347 ? -21.870 -15.917 2.170 1.00 57.84 ? 347 SER B N 347 SER B N 1 ATOM 4000 C CA . SER B 2 347 ? -20.829 -16.939 2.131 1.00 57.84 ? 347 SER B CA 347 SER B CA 1 ATOM 4001 C C . SER B 2 347 ? -20.919 -17.868 3.337 1.00 57.84 ? 347 SER B C 347 SER B C 1 ATOM 4002 O O . SER B 2 347 ? -21.120 -17.411 4.465 1.00 57.84 ? 347 SER B O 347 SER B O 1 ATOM 4003 C CB . SER B 2 347 ? -19.444 -16.293 2.077 1.00 57.84 ? 347 SER B CB 347 SER B CB 1 ATOM 4004 O OG . SER B 2 347 ? -18.426 -17.277 2.136 1.00 57.84 ? 347 SER B OG 347 SER B OG 1 ATOM 4005 N N . HIS B 2 348 ? -21.174 -19.179 3.147 1.00 59.38 ? 348 HIS B N 348 HIS B N 1 ATOM 4006 C CA . HIS B 2 348 ? -21.412 -20.248 4.110 1.00 59.38 ? 348 HIS B CA 348 HIS B CA 1 ATOM 4007 C C . HIS B 2 348 ? -20.100 -20.859 4.591 1.00 59.38 ? 348 HIS B C 348 HIS B C 1 ATOM 4008 O O . HIS B 2 348 ? -20.104 -21.840 5.338 1.00 59.38 ? 348 HIS B O 348 HIS B O 1 ATOM 4009 C CB . HIS B 2 348 ? -22.302 -21.331 3.499 1.00 59.38 ? 348 HIS B CB 348 HIS B CB 1 ATOM 4010 C CG . HIS B 2 348 ? -23.647 -20.833 3.072 1.00 59.38 ? 348 HIS B CG 348 HIS B CG 1 ATOM 4011 N ND1 . HIS B 2 348 ? -24.606 -20.420 3.970 1.00 59.38 ? 348 HIS B ND1 348 HIS B ND1 1 ATOM 4012 C CD2 . HIS B 2 348 ? -24.188 -20.681 1.841 1.00 59.38 ? 348 HIS B CD2 348 HIS B CD2 1 ATOM 4013 C CE1 . HIS B 2 348 ? -25.684 -20.034 3.308 1.00 59.38 ? 348 HIS B CE1 348 HIS B CE1 1 ATOM 4014 N NE2 . HIS B 2 348 ? -25.456 -20.182 2.014 1.00 59.38 ? 348 HIS B NE2 348 HIS B NE2 1 ATOM 4015 N N . LYS B 2 349 ? -18.892 -20.164 4.442 1.00 66.73 ? 349 LYS B N 349 LYS B N 1 ATOM 4016 C CA . LYS B 2 349 ? -17.686 -20.891 4.828 1.00 66.73 ? 349 LYS B CA 349 LYS B CA 1 ATOM 4017 C C . LYS B 2 349 ? -17.206 -20.462 6.212 1.00 66.73 ? 349 LYS B C 349 LYS B C 1 ATOM 4018 O O . LYS B 2 349 ? -17.245 -19.277 6.549 1.00 66.73 ? 349 LYS B O 349 LYS B O 1 ATOM 4019 C CB . LYS B 2 349 ? -16.576 -20.675 3.798 1.00 66.73 ? 349 LYS B CB 349 LYS B CB 1 ATOM 4020 C CG . LYS B 2 349 ? -16.749 -21.487 2.523 1.00 66.73 ? 349 LYS B CG 349 LYS B CG 1 ATOM 4021 C CD . LYS B 2 349 ? -15.520 -21.391 1.628 1.00 66.73 ? 349 LYS B CD 349 LYS B CD 1 ATOM 4022 C CE . LYS B 2 349 ? -15.715 -22.154 0.325 1.00 66.73 ? 349 LYS B CE 349 LYS B CE 1 ATOM 4023 N NZ . LYS B 2 349 ? -14.498 -22.096 -0.538 1.00 66.73 ? 349 LYS B NZ 349 LYS B NZ 1 ATOM 4024 N N . ALA B 2 350 ? -16.843 -21.507 6.999 1.00 65.78 ? 350 ALA B N 350 ALA B N 1 ATOM 4025 C CA . ALA B 2 350 ? -16.225 -21.384 8.317 1.00 65.78 ? 350 ALA B CA 350 ALA B CA 1 ATOM 4026 C C . ALA B 2 350 ? -14.830 -20.774 8.214 1.00 65.78 ? 350 ALA B C 350 ALA B C 1 ATOM 4027 O O . ALA B 2 350 ? -14.052 -21.134 7.327 1.00 65.78 ? 350 ALA B O 350 ALA B O 1 ATOM 4028 C CB . ALA B 2 350 ? -16.156 -22.747 9.001 1.00 65.78 ? 350 ALA B CB 350 ALA B CB 1 ATOM 4029 N N . GLY B 2 351 ? -14.623 -19.474 8.631 1.00 70.29 ? 351 GLY B N 351 GLY B N 1 ATOM 4030 C CA . GLY B 2 351 ? -13.305 -18.866 8.719 1.00 70.29 ? 351 GLY B CA 351 GLY B CA 1 ATOM 4031 C C . GLY B 2 351 ? -13.145 -17.656 7.817 1.00 70.29 ? 351 GLY B C 351 GLY B C 1 ATOM 4032 O O . GLY B 2 351 ? -12.049 -17.103 7.701 1.00 70.29 ? 351 GLY B O 351 GLY B O 1 ATOM 4033 N N . GLU B 2 352 ? -14.227 -17.269 7.073 1.00 80.71 ? 352 GLU B N 352 GLU B N 1 ATOM 4034 C CA . GLU B 2 352 ? -14.171 -16.085 6.220 1.00 80.71 ? 352 GLU B CA 352 GLU B CA 1 ATOM 4035 C C . GLU B 2 352 ? -14.404 -14.812 7.027 1.00 80.71 ? 352 GLU B C 352 GLU B C 1 ATOM 4036 O O . GLU B 2 352 ? -15.191 -14.807 7.976 1.00 80.71 ? 352 GLU B O 352 GLU B O 1 ATOM 4037 C CB . GLU B 2 352 ? -15.199 -16.188 5.091 1.00 80.71 ? 352 GLU B CB 352 GLU B CB 1 ATOM 4038 C CG . GLU B 2 352 ? -15.028 -15.135 4.005 1.00 80.71 ? 352 GLU B CG 352 GLU B CG 1 ATOM 4039 C CD . GLU B 2 352 ? -16.019 -15.284 2.863 1.00 80.71 ? 352 GLU B CD 352 GLU B CD 1 ATOM 4040 O OE1 . GLU B 2 352 ? -15.985 -14.462 1.918 1.00 80.71 ? 352 GLU B OE1 352 GLU B OE1 1 ATOM 4041 O OE2 . GLU B 2 352 ? -16.838 -16.229 2.912 1.00 80.71 ? 352 GLU B OE2 352 GLU B OE2 1 ATOM 4042 N N . LEU B 2 353 ? -13.670 -13.862 6.648 1.00 87.45 ? 353 LEU B N 353 LEU B N 1 ATOM 4043 C CA . LEU B 2 353 ? -13.774 -12.567 7.311 1.00 87.45 ? 353 LEU B CA 353 LEU B CA 1 ATOM 4044 C C . LEU B 2 353 ? -14.901 -11.736 6.707 1.00 87.45 ? 353 LEU B C 353 LEU B C 1 ATOM 4045 O O . LEU B 2 353 ? -14.988 -11.595 5.485 1.00 87.45 ? 353 LEU B O 353 LEU B O 1 ATOM 4046 C CB . LEU B 2 353 ? -12.451 -11.804 7.209 1.00 87.45 ? 353 LEU B CB 353 LEU B CB 1 ATOM 4047 C CG . LEU B 2 353 ? -12.430 -10.399 7.814 1.00 87.45 ? 353 LEU B CG 353 LEU B CG 1 ATOM 4048 C CD1 . LEU B 2 353 ? -12.502 -10.475 9.335 1.00 87.45 ? 353 LEU B CD1 353 LEU B CD1 1 ATOM 4049 C CD2 . LEU B 2 353 ? -11.181 -9.644 7.370 1.00 87.45 ? 353 LEU B CD2 353 LEU B CD2 1 ATOM 4050 N N . ILE B 2 354 ? -15.825 -11.375 7.523 1.00 89.30 ? 354 ILE B N 354 ILE B N 1 ATOM 4051 C CA . ILE B 2 354 ? -16.893 -10.464 7.126 1.00 89.30 ? 354 ILE B CA 354 ILE B CA 1 ATOM 4052 C C . ILE B 2 354 ? -16.649 -9.086 7.736 1.00 89.30 ? 354 ILE B C 354 ILE B C 1 ATOM 4053 O O . ILE B 2 354 ? -16.545 -8.950 8.957 1.00 89.30 ? 354 ILE B O 354 ILE B O 1 ATOM 4054 C CB . ILE B 2 354 ? -18.279 -11.000 7.551 1.00 89.30 ? 354 ILE B CB 354 ILE B CB 1 ATOM 4055 C CG1 . ILE B 2 354 ? -18.523 -12.388 6.946 1.00 89.30 ? 354 ILE B CG1 354 ILE B CG1 1 ATOM 4056 C CG2 . ILE B 2 354 ? -19.385 -10.022 7.143 1.00 89.30 ? 354 ILE B CG2 354 ILE B CG2 1 ATOM 4057 C CD1 . ILE B 2 354 ? -19.741 -13.105 7.513 1.00 89.30 ? 354 ILE B CD1 354 ILE B CD1 1 ATOM 4058 N N . ALA B 2 355 ? -16.443 -8.172 6.801 1.00 90.39 ? 355 ALA B N 355 ALA B N 1 ATOM 4059 C CA . ALA B 2 355 ? -16.194 -6.810 7.265 1.00 90.39 ? 355 ALA B CA 355 ALA B CA 1 ATOM 4060 C C . ALA B 2 355 ? -16.606 -5.787 6.210 1.00 90.39 ? 355 ALA B C 355 ALA B C 1 ATOM 4061 O O . ALA B 2 355 ? -16.539 -6.063 5.010 1.00 90.39 ? 355 ALA B O 355 ALA B O 1 ATOM 4062 C CB . ALA B 2 355 ? -14.721 -6.632 7.627 1.00 90.39 ? 355 ALA B CB 355 ALA B CB 1 ATOM 4063 N N . ARG B 2 356 ? -17.029 -4.732 6.702 1.00 89.15 ? 356 ARG B N 356 ARG B N 1 ATOM 4064 C CA . ARG B 2 356 ? -17.375 -3.640 5.798 1.00 89.15 ? 356 ARG B CA 356 ARG B CA 1 ATOM 4065 C C . ARG B 2 356 ? -16.192 -2.698 5.600 1.00 89.15 ? 356 ARG B C 356 ARG B C 1 ATOM 4066 O O . ARG B 2 356 ? -15.416 -2.464 6.529 1.00 89.15 ? 356 ARG B O 356 ARG B O 1 ATOM 4067 C CB . ARG B 2 356 ? -18.581 -2.863 6.329 1.00 89.15 ? 356 ARG B CB 356 ARG B CB 1 ATOM 4068 C CG . ARG B 2 356 ? -19.841 -3.702 6.470 1.00 89.15 ? 356 ARG B CG 356 ARG B CG 1 ATOM 4069 C CD . ARG B 2 356 ? -21.012 -2.878 6.989 1.00 89.15 ? 356 ARG B CD 356 ARG B CD 1 ATOM 4070 N NE . ARG B 2 356 ? -20.825 -2.496 8.385 1.00 89.15 ? 356 ARG B NE 356 ARG B NE 1 ATOM 4071 C CZ . ARG B 2 356 ? -21.682 -1.764 9.092 1.00 89.15 ? 356 ARG B CZ 356 ARG B CZ 1 ATOM 4072 N NH1 . ARG B 2 356 ? -22.807 -1.320 8.544 1.00 89.15 ? 356 ARG B NH1 356 ARG B NH1 1 ATOM 4073 N NH2 . ARG B 2 356 ? -21.413 -1.475 10.357 1.00 89.15 ? 356 ARG B NH2 356 ARG B NH2 1 ATOM 4074 N N . PRO B 2 357 ? -16.053 -2.121 4.419 1.00 89.70 ? 357 PRO B N 357 PRO B N 1 ATOM 4075 C CA . PRO B 2 357 ? -14.979 -1.154 4.180 1.00 89.70 ? 357 PRO B CA 357 PRO B CA 1 ATOM 4076 C C . PRO B 2 357 ? -15.220 0.181 4.881 1.00 89.70 ? 357 PRO B C 357 PRO B C 1 ATOM 4077 O O . PRO B 2 357 ? -16.367 0.615 5.011 1.00 89.70 ? 357 PRO B O 357 PRO B O 1 ATOM 4078 C CB . PRO B 2 357 ? -14.990 -0.983 2.659 1.00 89.70 ? 357 PRO B CB 357 PRO B CB 1 ATOM 4079 C CG . PRO B 2 357 ? -15.774 -2.148 2.149 1.00 89.70 ? 357 PRO B CG 357 PRO B CG 1 ATOM 4080 C CD . PRO B 2 357 ? -16.692 -2.620 3.240 1.00 89.70 ? 357 PRO B CD 357 PRO B CD 1 ATOM 4081 N N . GLY B 2 358 ? -14.178 0.825 5.417 1.00 88.87 ? 358 GLY B N 358 GLY B N 1 ATOM 4082 C CA . GLY B 2 358 ? -14.312 2.046 6.195 1.00 88.87 ? 358 GLY B CA 358 GLY B CA 1 ATOM 4083 C C . GLY B 2 358 ? -13.842 3.282 5.452 1.00 88.87 ? 358 GLY B C 358 GLY B C 1 ATOM 4084 O O . GLY B 2 358 ? -14.142 4.408 5.855 1.00 88.87 ? 358 GLY B O 358 GLY B O 1 ATOM 4085 N N . ALA B 2 359 ? -13.241 3.142 4.376 1.00 90.65 ? 359 ALA B N 359 ALA B N 1 ATOM 4086 C CA . ALA B 2 359 ? -12.754 4.276 3.595 1.00 90.65 ? 359 ALA B CA 359 ALA B CA 1 ATOM 4087 C C . ALA B 2 359 ? -13.569 4.451 2.316 1.00 90.65 ? 359 ALA B C 359 ALA B C 1 ATOM 4088 O O . ALA B 2 359 ? -13.898 3.472 1.643 1.00 90.65 ? 359 ALA B O 359 ALA B O 1 ATOM 4089 C CB . ALA B 2 359 ? -11.276 4.096 3.259 1.00 90.65 ? 359 ALA B CB 359 ALA B CB 1 ATOM 4090 N N . TYR B 2 360 ? -13.860 5.765 2.033 1.00 90.55 ? 360 TYR B N 360 TYR B N 1 ATOM 4091 C CA . TYR B 2 360 ? -14.713 6.091 0.896 1.00 90.55 ? 360 TYR B CA 360 TYR B CA 1 ATOM 4092 C C . TYR B 2 360 ? -14.058 7.140 0.005 1.00 90.55 ? 360 TYR B C 360 TYR B C 1 ATOM 4093 O O . TYR B 2 360 ? -13.319 8.000 0.489 1.00 90.55 ? 360 TYR B O 360 TYR B O 1 ATOM 4094 C CB . TYR B 2 360 ? -16.079 6.592 1.374 1.00 90.55 ? 360 TYR B CB 360 TYR B CB 1 ATOM 4095 C CG . TYR B 2 360 ? -16.795 5.625 2.286 1.00 90.55 ? 360 TYR B CG 360 TYR B CG 1 ATOM 4096 C CD1 . TYR B 2 360 ? -17.615 4.625 1.767 1.00 90.55 ? 360 TYR B CD1 360 TYR B CD1 1 ATOM 4097 C CD2 . TYR B 2 360 ? -16.655 5.709 3.667 1.00 90.55 ? 360 TYR B CD2 360 TYR B CD2 1 ATOM 4098 C CE1 . TYR B 2 360 ? -18.278 3.733 2.603 1.00 90.55 ? 360 TYR B CE1 360 TYR B CE1 1 ATOM 4099 C CE2 . TYR B 2 360 ? -17.313 4.823 4.512 1.00 90.55 ? 360 TYR B CE2 360 TYR B CE2 1 ATOM 4100 C CZ . TYR B 2 360 ? -18.121 3.839 3.972 1.00 90.55 ? 360 TYR B CZ 360 TYR B CZ 1 ATOM 4101 O OH . TYR B 2 360 ? -18.775 2.959 4.804 1.00 90.55 ? 360 TYR B OH 360 TYR B OH 1 ATOM 4102 N N . VAL B 2 361 ? -14.357 6.938 -1.257 1.00 87.61 ? 361 VAL B N 361 VAL B N 1 ATOM 4103 C CA . VAL B 2 361 ? -13.886 7.912 -2.236 1.00 87.61 ? 361 VAL B CA 361 VAL B CA 1 ATOM 4104 C C . VAL B 2 361 ? -15.073 8.491 -3.002 1.00 87.61 ? 361 VAL B C 361 VAL B C 1 ATOM 4105 O O . VAL B 2 361 ? -15.858 7.749 -3.596 1.00 87.61 ? 361 VAL B O 361 VAL B O 1 ATOM 4106 C CB . VAL B 2 361 ? -12.873 7.284 -3.220 1.00 87.61 ? 361 VAL B CB 361 VAL B CB 1 ATOM 4107 C CG1 . VAL B 2 361 ? -12.397 8.318 -4.238 1.00 87.61 ? 361 VAL B CG1 361 VAL B CG1 1 ATOM 4108 C CG2 . VAL B 2 361 ? -11.687 6.694 -2.459 1.00 87.61 ? 361 VAL B CG2 361 VAL B CG2 1 ATOM 4109 N N . ARG B 2 362 ? -15.088 9.912 -3.023 1.00 87.10 ? 362 ARG B N 362 ARG B N 1 ATOM 4110 C CA . ARG B 2 362 ? -16.183 10.583 -3.716 1.00 87.10 ? 362 ARG B CA 362 ARG B CA 1 ATOM 4111 C C . ARG B 2 362 ? -15.999 10.513 -5.228 1.00 87.10 ? 362 ARG B C 362 ARG B C 1 ATOM 4112 O O . ARG B 2 362 ? -14.929 10.841 -5.744 1.00 87.10 ? 362 ARG B O 362 ARG B O 1 ATOM 4113 C CB . ARG B 2 362 ? -16.289 12.042 -3.268 1.00 87.10 ? 362 ARG B CB 362 ARG B CB 1 ATOM 4114 C CG . ARG B 2 362 ? -17.364 12.833 -3.996 1.00 87.10 ? 362 ARG B CG 362 ARG B CG 1 ATOM 4115 C CD . ARG B 2 362 ? -18.759 12.313 -3.679 1.00 87.10 ? 362 ARG B CD 362 ARG B CD 1 ATOM 4116 N NE . ARG B 2 362 ? -19.787 13.044 -4.414 1.00 87.10 ? 362 ARG B NE 362 ARG B NE 1 ATOM 4117 C CZ . ARG B 2 362 ? -20.231 12.716 -5.625 1.00 87.10 ? 362 ARG B CZ 362 ARG B CZ 1 ATOM 4118 N NH1 . ARG B 2 362 ? -19.743 11.659 -6.263 1.00 87.10 ? 362 ARG B NH1 362 ARG B NH1 1 ATOM 4119 N NH2 . ARG B 2 362 ? -21.170 13.452 -6.202 1.00 87.10 ? 362 ARG B NH2 362 ARG B NH2 1 ATOM 4120 N N . ASP B 2 363 ? -16.990 9.977 -5.840 1.00 81.30 ? 363 ASP B N 363 ASP B N 1 ATOM 4121 C CA . ASP B 2 363 ? -17.021 10.001 -7.299 1.00 81.30 ? 363 ASP B CA 363 ASP B CA 1 ATOM 4122 C C . ASP B 2 363 ? -17.738 11.248 -7.813 1.00 81.30 ? 363 ASP B C 363 ASP B C 1 ATOM 4123 O O . ASP B 2 363 ? -18.960 11.359 -7.698 1.00 81.30 ? 363 ASP B O 363 ASP B O 1 ATOM 4124 C CB . ASP B 2 363 ? -17.699 8.743 -7.844 1.00 81.30 ? 363 ASP B CB 363 ASP B CB 1 ATOM 4125 C CG . ASP B 2 363 ? -17.485 8.551 -9.335 1.00 81.30 ? 363 ASP B CG 363 ASP B CG 1 ATOM 4126 O OD1 . ASP B 2 363 ? -16.956 9.469 -9.998 1.00 81.30 ? 363 ASP B OD1 363 ASP B OD1 1 ATOM 4127 O OD2 . ASP B 2 363 ? -17.851 7.473 -9.852 1.00 81.30 ? 363 ASP B OD2 363 ASP B OD2 1 ATOM 4128 N N . PHE B 2 364 ? -16.985 12.229 -8.448 1.00 76.82 ? 364 PHE B N 364 PHE B N 1 ATOM 4129 C CA . PHE B 2 364 ? -17.522 13.525 -8.845 1.00 76.82 ? 364 PHE B CA 364 PHE B CA 1 ATOM 4130 C C . PHE B 2 364 ? -18.174 13.442 -10.220 1.00 76.82 ? 364 PHE B C 364 PHE B C 1 ATOM 4131 O O . PHE B 2 364 ? -18.806 14.399 -10.672 1.00 76.82 ? 364 PHE B O 364 PHE B O 1 ATOM 4132 C CB . PHE B 2 364 ? -16.418 14.587 -8.850 1.00 76.82 ? 364 PHE B CB 364 PHE B CB 1 ATOM 4133 C CG . PHE B 2 364 ? -15.932 14.964 -7.477 1.00 76.82 ? 364 PHE B CG 364 PHE B CG 1 ATOM 4134 C CD1 . PHE B 2 364 ? -16.576 15.954 -6.744 1.00 76.82 ? 364 PHE B CD1 364 PHE B CD1 1 ATOM 4135 C CD2 . PHE B 2 364 ? -14.831 14.328 -6.918 1.00 76.82 ? 364 PHE B CD2 364 PHE B CD2 1 ATOM 4136 C CE1 . PHE B 2 364 ? -16.128 16.305 -5.473 1.00 76.82 ? 364 PHE B CE1 364 PHE B CE1 1 ATOM 4137 C CE2 . PHE B 2 364 ? -14.378 14.673 -5.648 1.00 76.82 ? 364 PHE B CE2 364 PHE B CE2 1 ATOM 4138 C CZ . PHE B 2 364 ? -15.028 15.663 -4.927 1.00 76.82 ? 364 PHE B CZ 364 PHE B CZ 1 ATOM 4139 N N . ALA B 2 365 ? -18.139 12.235 -10.766 1.00 72.04 ? 365 ALA B N 365 ALA B N 1 ATOM 4140 C CA . ALA B 2 365 ? -18.678 12.057 -12.112 1.00 72.04 ? 365 ALA B CA 365 ALA B CA 1 ATOM 4141 C C . ALA B 2 365 ? -20.167 11.728 -12.067 1.00 72.04 ? 365 ALA B C 365 ALA B C 1 ATOM 4142 O O . ALA B 2 365 ? -20.885 11.935 -13.048 1.00 72.04 ? 365 ALA B O 365 ALA B O 1 ATOM 4143 C CB . ALA B 2 365 ? -17.916 10.958 -12.849 1.00 72.04 ? 365 ALA B CB 365 ALA B CB 1 ATOM 4144 N N . GLN B 2 366 ? -20.679 11.391 -10.983 1.00 74.69 ? 366 GLN B N 366 GLN B N 1 ATOM 4145 C CA . GLN B 2 366 ? -22.063 10.940 -10.872 1.00 74.69 ? 366 GLN B CA 366 GLN B CA 1 ATOM 4146 C C . GLN B 2 366 ? -22.890 11.907 -10.031 1.00 74.69 ? 366 GLN B C 366 GLN B C 1 ATOM 4147 O O . GLN B 2 366 ? -22.406 12.440 -9.030 1.00 74.69 ? 366 GLN B O 366 GLN B O 1 ATOM 4148 C CB . GLN B 2 366 ? -22.123 9.535 -10.269 1.00 74.69 ? 366 GLN B CB 366 GLN B CB 1 ATOM 4149 C CG . GLN B 2 366 ? -21.546 8.453 -11.171 1.00 74.69 ? 366 GLN B CG 366 GLN B CG 1 ATOM 4150 C CD . GLN B 2 366 ? -21.770 7.055 -10.627 1.00 74.69 ? 366 GLN B CD 366 GLN B CD 1 ATOM 4151 O OE1 . GLN B 2 366 ? -22.330 6.879 -9.540 1.00 74.69 ? 366 GLN B OE1 366 GLN B OE1 1 ATOM 4152 N NE2 . GLN B 2 366 ? -21.333 6.049 -11.378 1.00 74.69 ? 366 GLN B NE2 366 GLN B NE2 1 ATOM 4153 N N . THR B 2 367 ? -23.991 12.357 -10.569 1.00 77.53 ? 367 THR B N 367 THR B N 1 ATOM 4154 C CA . THR B 2 367 ? -24.920 13.184 -9.807 1.00 77.53 ? 367 THR B CA 367 THR B CA 1 ATOM 4155 C C . THR B 2 367 ? -26.270 12.487 -9.662 1.00 77.53 ? 367 THR B C 367 THR B C 1 ATOM 4156 O O . THR B 2 367 ? -26.721 11.799 -10.580 1.00 77.53 ? 367 THR B O 367 THR B O 1 ATOM 4157 C CB . THR B 2 367 ? -25.117 14.559 -10.471 1.00 77.53 ? 367 THR B CB 367 THR B CB 1 ATOM 4158 O OG1 . THR B 2 367 ? -25.616 14.374 -11.801 1.00 77.53 ? 367 THR B OG1 367 THR B OG1 1 ATOM 4159 C CG2 . THR B 2 367 ? -23.804 15.332 -10.535 1.00 77.53 ? 367 THR B CG2 367 THR B CG2 1 ATOM 4160 N N . HIS B 2 368 ? -26.647 12.421 -8.469 1.00 83.04 ? 368 HIS B N 368 HIS B N 1 ATOM 4161 C CA . HIS B 2 368 ? -27.926 11.780 -8.185 1.00 83.04 ? 368 HIS B CA 368 HIS B CA 1 ATOM 4162 C C . HIS B 2 368 ? -28.712 12.561 -7.137 1.00 83.04 ? 368 HIS B C 368 HIS B C 1 ATOM 4163 O O . HIS B 2 368 ? -28.124 13.216 -6.273 1.00 83.04 ? 368 HIS B O 368 HIS B O 1 ATOM 4164 C CB . HIS B 2 368 ? -27.711 10.340 -7.715 1.00 83.04 ? 368 HIS B CB 368 HIS B CB 1 ATOM 4165 C CG . HIS B 2 368 ? -28.947 9.500 -7.773 1.00 83.04 ? 368 HIS B CG 368 HIS B CG 1 ATOM 4166 N ND1 . HIS B 2 368 ? -29.869 9.461 -6.749 1.00 83.04 ? 368 HIS B ND1 368 HIS B ND1 1 ATOM 4167 C CD2 . HIS B 2 368 ? -29.413 8.668 -8.734 1.00 83.04 ? 368 HIS B CD2 368 HIS B CD2 1 ATOM 4168 C CE1 . HIS B 2 368 ? -30.851 8.639 -7.080 1.00 83.04 ? 368 HIS B CE1 368 HIS B CE1 1 ATOM 4169 N NE2 . HIS B 2 368 ? -30.598 8.145 -8.280 1.00 83.04 ? 368 HIS B NE2 368 HIS B NE2 1 ATOM 4170 N N . ILE B 2 369 ? -30.045 12.539 -7.345 1.00 85.34 ? 369 ILE B N 369 ILE B N 1 ATOM 4171 C CA . ILE B 2 369 ? -30.927 13.118 -6.337 1.00 85.34 ? 369 ILE B CA 369 ILE B CA 1 ATOM 4172 C C . ILE B 2 369 ? -31.190 12.097 -5.233 1.00 85.34 ? 369 ILE B C 369 ILE B C 1 ATOM 4173 O O . ILE B 2 369 ? -31.769 11.037 -5.484 1.00 85.34 ? 369 ILE B O 369 ILE B O 1 ATOM 4174 C CB . ILE B 2 369 ? -32.260 13.592 -6.959 1.00 85.34 ? 369 ILE B CB 369 ILE B CB 1 ATOM 4175 C CG1 . ILE B 2 369 ? -32.001 14.651 -8.036 1.00 85.34 ? 369 ILE B CG1 369 ILE B CG1 1 ATOM 4176 C CG2 . ILE B 2 369 ? -33.199 14.131 -5.876 1.00 85.34 ? 369 ILE B CG2 369 ILE B CG2 1 ATOM 4177 C CD1 . ILE B 2 369 ? -33.232 15.016 -8.854 1.00 85.34 ? 369 ILE B CD1 369 ILE B CD1 1 ATOM 4178 N N . LEU B 2 370 ? -30.657 12.399 -4.062 1.00 89.47 ? 370 LEU B N 370 LEU B N 1 ATOM 4179 C CA . LEU B 2 370 ? -30.762 11.494 -2.922 1.00 89.47 ? 370 LEU B CA 370 LEU B CA 1 ATOM 4180 C C . LEU B 2 370 ? -32.114 11.642 -2.233 1.00 89.47 ? 370 LEU B C 370 LEU B C 1 ATOM 4181 O O . LEU B 2 370 ? -32.657 12.746 -2.153 1.00 89.47 ? 370 LEU B O 370 LEU B O 1 ATOM 4182 C CB . LEU B 2 370 ? -29.634 11.759 -1.922 1.00 89.47 ? 370 LEU B CB 370 LEU B CB 1 ATOM 4183 C CG . LEU B 2 370 ? -28.207 11.613 -2.453 1.00 89.47 ? 370 LEU B CG 370 LEU B CG 1 ATOM 4184 C CD1 . LEU B 2 370 ? -27.201 12.088 -1.410 1.00 89.47 ? 370 LEU B CD1 370 LEU B CD1 1 ATOM 4185 C CD2 . LEU B 2 370 ? -27.930 10.167 -2.851 1.00 89.47 ? 370 LEU B CD2 370 LEU B CD2 1 ATOM 4186 N N . LYS B 2 371 ? -32.762 10.556 -1.712 1.00 91.50 ? 371 LYS B N 371 LYS B N 1 ATOM 4187 C CA . LYS B 2 371 ? -34.093 10.505 -1.114 1.00 91.50 ? 371 LYS B CA 371 LYS B CA 1 ATOM 4188 C C . LYS B 2 371 ? -34.044 10.865 0.368 1.00 91.50 ? 371 LYS B C 371 LYS B C 1 ATOM 4189 O O . LYS B 2 371 ? -34.941 11.539 0.879 1.00 91.50 ? 371 LYS B O 371 LYS B O 1 ATOM 4190 C CB . LYS B 2 371 ? -34.710 9.118 -1.296 1.00 91.50 ? 371 LYS B CB 371 LYS B CB 1 ATOM 4191 C CG . LYS B 2 371 ? -35.010 8.759 -2.744 1.00 91.50 ? 371 LYS B CG 371 LYS B CG 1 ATOM 4192 C CD . LYS B 2 371 ? -35.689 7.400 -2.854 1.00 91.50 ? 371 LYS B CD 371 LYS B CD 1 ATOM 4193 C CE . LYS B 2 371 ? -35.974 7.032 -4.304 1.00 91.50 ? 371 LYS B CE 371 LYS B CE 1 ATOM 4194 N NZ . LYS B 2 371 ? -36.610 5.686 -4.420 1.00 91.50 ? 371 LYS B NZ 371 LYS B NZ 1 ATOM 4195 N N . LEU B 2 372 ? -33.012 10.450 1.076 1.00 91.44 ? 372 LEU B N 372 LEU B N 1 ATOM 4196 C CA . LEU B 2 372 ? -32.882 10.656 2.515 1.00 91.44 ? 372 LEU B CA 372 LEU B CA 1 ATOM 4197 C C . LEU B 2 372 ? -32.248 12.010 2.814 1.00 91.44 ? 372 LEU B C 372 LEU B C 1 ATOM 4198 O O . LEU B 2 372 ? -31.279 12.405 2.162 1.00 91.44 ? 372 LEU B O 372 LEU B O 1 ATOM 4199 C CB . LEU B 2 372 ? -32.047 9.538 3.144 1.00 91.44 ? 372 LEU B CB 372 LEU B CB 1 ATOM 4200 C CG . LEU B 2 372 ? -32.622 8.124 3.043 1.00 91.44 ? 372 LEU B CG 372 LEU B CG 1 ATOM 4201 C CD1 . LEU B 2 372 ? -31.622 7.106 3.583 1.00 91.44 ? 372 LEU B CD1 372 LEU B CD1 1 ATOM 4202 C CD2 . LEU B 2 372 ? -33.946 8.030 3.794 1.00 91.44 ? 372 LEU B CD2 372 LEU B CD2 1 ATOM 4203 N N . LYS B 2 373 ? -32.897 12.766 3.770 1.00 92.18 ? 373 LYS B N 373 LYS B N 1 ATOM 4204 C CA . LYS B 2 373 ? -32.352 14.052 4.195 1.00 92.18 ? 373 LYS B CA 373 LYS B CA 1 ATOM 4205 C C . LYS B 2 373 ? -30.937 13.895 4.744 1.00 92.18 ? 373 LYS B C 373 LYS B C 1 ATOM 4206 O O . LYS B 2 373 ? -30.061 14.715 4.461 1.00 92.18 ? 373 LYS B O 373 LYS B O 1 ATOM 4207 C CB . LYS B 2 373 ? -33.254 14.697 5.248 1.00 92.18 ? 373 LYS B CB 373 LYS B CB 1 ATOM 4208 C CG . LYS B 2 373 ? -32.867 16.124 5.605 1.00 92.18 ? 373 LYS B CG 373 LYS B CG 1 ATOM 4209 C CD . LYS B 2 373 ? -33.827 16.726 6.623 1.00 92.18 ? 373 LYS B CD 373 LYS B CD 1 ATOM 4210 C CE . LYS B 2 373 ? -33.388 18.119 7.053 1.00 92.18 ? 373 LYS B CE 373 LYS B CE 1 ATOM 4211 N NZ . LYS B 2 373 ? -34.314 18.704 8.067 1.00 92.18 ? 373 LYS B NZ 373 LYS B NZ 1 ATOM 4212 N N . THR B 2 374 ? -30.715 12.803 5.497 1.00 91.98 ? 374 THR B N 374 THR B N 1 ATOM 4213 C CA . THR B 2 374 ? -29.411 12.542 6.097 1.00 91.98 ? 374 THR B CA 374 THR B CA 1 ATOM 4214 C C . THR B 2 374 ? -28.352 12.332 5.019 1.00 91.98 ? 374 THR B C 374 THR B C 1 ATOM 4215 O O . THR B 2 374 ? -27.210 12.771 5.169 1.00 91.98 ? 374 THR B O 374 THR B O 1 ATOM 4216 C CB . THR B 2 374 ? -29.458 11.312 7.022 1.00 91.98 ? 374 THR B CB 374 THR B CB 1 ATOM 4217 O OG1 . THR B 2 374 ? -29.993 10.197 6.299 1.00 91.98 ? 374 THR B OG1 374 THR B OG1 1 ATOM 4218 C CG2 . THR B 2 374 ? -30.330 11.576 8.245 1.00 91.98 ? 374 THR B CG2 374 THR B CG2 1 ATOM 4219 N N . SER B 2 375 ? -28.711 11.655 3.951 1.00 93.62 ? 375 SER B N 375 SER B N 1 ATOM 4220 C CA . SER B 2 375 ? -27.801 11.400 2.839 1.00 93.62 ? 375 SER B CA 375 SER B CA 1 ATOM 4221 C C . SER B 2 375 ? -27.420 12.695 2.129 1.00 93.62 ? 375 SER B C 375 SER B C 1 ATOM 4222 O O . SER B 2 375 ? -26.258 12.891 1.765 1.00 93.62 ? 375 SER B O 375 SER B O 1 ATOM 4223 C CB . SER B 2 375 ? -28.433 10.428 1.841 1.00 93.62 ? 375 SER B CB 375 SER B CB 1 ATOM 4224 O OG . SER B 2 375 ? -28.690 9.176 2.453 1.00 93.62 ? 375 SER B OG 375 SER B OG 1 ATOM 4225 N N . ARG B 2 376 ? -28.439 13.608 1.951 1.00 92.98 ? 376 ARG B N 376 ARG B N 1 ATOM 4226 C CA . ARG B 2 376 ? -28.175 14.899 1.326 1.00 92.98 ? 376 ARG B CA 376 ARG B CA 1 ATOM 4227 C C . ARG B 2 376 ? -27.205 15.725 2.163 1.00 92.98 ? 376 ARG B C 376 ARG B C 1 ATOM 4228 O O . ARG B 2 376 ? -26.282 16.341 1.626 1.00 92.98 ? 376 ARG B O 376 ARG B O 1 ATOM 4229 C CB . ARG B 2 376 ? -29.479 15.674 1.119 1.00 92.98 ? 376 ARG B CB 376 ARG B CB 1 ATOM 4230 C CG . ARG B 2 376 ? -30.403 15.058 0.080 1.00 92.98 ? 376 ARG B CG 376 ARG B CG 1 ATOM 4231 C CD . ARG B 2 376 ? -31.542 15.998 -0.289 1.00 92.98 ? 376 ARG B CD 376 ARG B CD 1 ATOM 4232 N NE . ARG B 2 376 ? -32.383 16.304 0.865 1.00 92.98 ? 376 ARG B NE 376 ARG B NE 1 ATOM 4233 C CZ . ARG B 2 376 ? -33.419 15.571 1.264 1.00 92.98 ? 376 ARG B CZ 376 ARG B CZ 1 ATOM 4234 N NH1 . ARG B 2 376 ? -33.764 14.470 0.607 1.00 92.98 ? 376 ARG B NH1 376 ARG B NH1 1 ATOM 4235 N NH2 . ARG B 2 376 ? -34.116 15.942 2.329 1.00 92.98 ? 376 ARG B NH2 376 ARG B NH2 1 ATOM 4236 N N . GLN B 2 377 ? -27.446 15.719 3.481 1.00 92.68 ? 377 GLN B N 377 GLN B N 1 ATOM 4237 C CA . GLN B 2 377 ? -26.576 16.450 4.397 1.00 92.68 ? 377 GLN B CA 377 GLN B CA 1 ATOM 4238 C C . GLN B 2 377 ? -25.163 15.872 4.393 1.00 92.68 ? 377 GLN B C 377 GLN B C 1 ATOM 4239 O O . GLN B 2 377 ? -24.182 16.618 4.376 1.00 92.68 ? 377 GLN B O 377 GLN B O 1 ATOM 4240 C CB . GLN B 2 377 ? -27.148 16.427 5.815 1.00 92.68 ? 377 GLN B CB 377 GLN B CB 1 ATOM 4241 C CG . GLN B 2 377 ? -28.405 17.269 5.985 1.00 92.68 ? 377 GLN B CG 377 GLN B CG 1 ATOM 4242 C CD . GLN B 2 377 ? -28.985 17.182 7.384 1.00 92.68 ? 377 GLN B CD 377 GLN B CD 1 ATOM 4243 O OE1 . GLN B 2 377 ? -28.548 16.367 8.203 1.00 92.68 ? 377 GLN B OE1 377 GLN B OE1 1 ATOM 4244 N NE2 . GLN B 2 377 ? -29.975 18.021 7.669 1.00 92.68 ? 377 GLN B NE2 377 GLN B NE2 1 ATOM 4245 N N . LEU B 2 378 ? -25.145 14.554 4.449 1.00 93.60 ? 378 LEU B N 378 LEU B N 1 ATOM 4246 C CA . LEU B 2 378 ? -23.860 13.863 4.451 1.00 93.60 ? 378 LEU B CA 378 LEU B CA 1 ATOM 4247 C C . LEU B 2 378 ? -23.096 14.132 3.159 1.00 93.60 ? 378 LEU B C 378 LEU B C 1 ATOM 4248 O O . LEU B 2 378 ? -21.885 14.360 3.185 1.00 93.60 ? 378 LEU B O 378 LEU B O 1 ATOM 4249 C CB . LEU B 2 378 ? -24.062 12.356 4.634 1.00 93.60 ? 378 LEU B CB 378 LEU B CB 1 ATOM 4250 C CG . LEU B 2 378 ? -22.793 11.517 4.792 1.00 93.60 ? 378 LEU B CG 378 LEU B CG 1 ATOM 4251 C CD1 . LEU B 2 378 ? -22.009 11.966 6.020 1.00 93.60 ? 378 LEU B CD1 378 LEU B CD1 1 ATOM 4252 C CD2 . LEU B 2 378 ? -23.141 10.035 4.886 1.00 93.60 ? 378 LEU B CD2 378 LEU B CD2 1 ATOM 4253 N N . LEU B 2 379 ? -23.740 14.067 2.041 1.00 92.12 ? 379 LEU B N 379 LEU B N 1 ATOM 4254 C CA . LEU B 2 379 ? -23.115 14.326 0.749 1.00 92.12 ? 379 LEU B CA 379 LEU B CA 1 ATOM 4255 C C . LEU B 2 379 ? -22.528 15.732 0.701 1.00 92.12 ? 379 LEU B C 379 LEU B C 1 ATOM 4256 O O . LEU B 2 379 ? -21.443 15.938 0.151 1.00 92.12 ? 379 LEU B O 379 LEU B O 1 ATOM 4257 C CB . LEU B 2 379 ? -24.131 14.146 -0.383 1.00 92.12 ? 379 LEU B CB 379 LEU B CB 1 ATOM 4258 C CG . LEU B 2 379 ? -23.593 14.295 -1.807 1.00 92.12 ? 379 LEU B CG 379 LEU B CG 1 ATOM 4259 C CD1 . LEU B 2 379 ? -22.503 13.261 -2.072 1.00 92.12 ? 379 LEU B CD1 379 LEU B CD1 1 ATOM 4260 C CD2 . LEU B 2 379 ? -24.722 14.161 -2.822 1.00 92.12 ? 379 LEU B CD2 379 LEU B CD2 1 ATOM 4261 N N . THR B 2 380 ? -23.312 16.718 1.264 1.00 91.78 ? 380 THR B N 380 THR B N 1 ATOM 4262 C CA . THR B 2 380 ? -22.809 18.087 1.318 1.00 91.78 ? 380 THR B CA 380 THR B CA 1 ATOM 4263 C C . THR B 2 380 ? -21.503 18.153 2.104 1.00 91.78 ? 380 THR B C 380 THR B C 1 ATOM 4264 O O . THR B 2 380 ? -20.565 18.845 1.702 1.00 91.78 ? 380 THR B O 380 THR B O 1 ATOM 4265 C CB . THR B 2 380 ? -23.842 19.037 1.952 1.00 91.78 ? 380 THR B CB 380 THR B CB 1 ATOM 4266 O OG1 . THR B 2 380 ? -25.054 18.995 1.187 1.00 91.78 ? 380 THR B OG1 380 THR B OG1 1 ATOM 4267 C CG2 . THR B 2 380 ? -23.324 20.471 1.983 1.00 91.78 ? 380 THR B CG2 380 THR B CG2 1 ATOM 4268 N N . LYS B 2 381 ? -21.438 17.415 3.198 1.00 92.53 ? 381 LYS B N 381 LYS B N 1 ATOM 4269 C CA . LYS B 2 381 ? -20.226 17.373 4.010 1.00 92.53 ? 381 LYS B CA 381 LYS B CA 1 ATOM 4270 C C . LYS B 2 381 ? -19.078 16.714 3.251 1.00 92.53 ? 381 LYS B C 381 LYS B C 1 ATOM 4271 O O . LYS B 2 381 ? -17.933 17.164 3.334 1.00 92.53 ? 381 LYS B O 381 LYS B O 1 ATOM 4272 C CB . LYS B 2 381 ? -20.484 16.627 5.320 1.00 92.53 ? 381 LYS B CB 381 LYS B CB 1 ATOM 4273 C CG . LYS B 2 381 ? -21.361 17.387 6.304 1.00 92.53 ? 381 LYS B CG 381 LYS B CG 1 ATOM 4274 C CD . LYS B 2 381 ? -21.497 16.641 7.625 1.00 92.53 ? 381 LYS B CD 381 LYS B CD 1 ATOM 4275 C CE . LYS B 2 381 ? -22.377 17.400 8.609 1.00 92.53 ? 381 LYS B CE 381 LYS B CE 1 ATOM 4276 N NZ . LYS B 2 381 ? -22.545 16.654 9.892 1.00 92.53 ? 381 LYS B NZ 381 LYS B NZ 1 ATOM 4277 N N . ILE B 2 382 ? -19.377 15.687 2.518 1.00 91.62 ? 382 ILE B N 382 ILE B N 1 ATOM 4278 C CA . ILE B 2 382 ? -18.387 14.956 1.734 1.00 91.62 ? 382 ILE B CA 382 ILE B CA 1 ATOM 4279 C C . ILE B 2 382 ? -17.846 15.853 0.623 1.00 91.62 ? 382 ILE B C 382 ILE B C 1 ATOM 4280 O O . ILE B 2 382 ? -16.642 15.864 0.356 1.00 91.62 ? 382 ILE B O 382 ILE B O 1 ATOM 4281 C CB . ILE B 2 382 ? -18.983 13.662 1.136 1.00 91.62 ? 382 ILE B CB 382 ILE B CB 1 ATOM 4282 C CG1 . ILE B 2 382 ? -19.329 12.669 2.251 1.00 91.62 ? 382 ILE B CG1 382 ILE B CG1 1 ATOM 4283 C CG2 . ILE B 2 382 ? -18.015 13.038 0.127 1.00 91.62 ? 382 ILE B CG2 382 ILE B CG2 1 ATOM 4284 C CD1 . ILE B 2 382 ? -20.131 11.464 1.780 1.00 91.62 ? 382 ILE B CD1 382 ILE B CD1 1 ATOM 4285 N N . ASP B 2 383 ? -18.817 16.634 0.025 1.00 87.86 ? 383 ASP B N 383 ASP B N 1 ATOM 4286 C CA . ASP B 2 383 ? -18.444 17.520 -1.074 1.00 87.86 ? 383 ASP B CA 383 ASP B CA 1 ATOM 4287 C C . ASP B 2 383 ? -17.445 18.578 -0.613 1.00 87.86 ? 383 ASP B C 383 ASP B C 1 ATOM 4288 O O . ASP B 2 383 ? -16.589 19.011 -1.387 1.00 87.86 ? 383 ASP B O 383 ASP B O 1 ATOM 4289 C CB . ASP B 2 383 ? -19.685 18.191 -1.667 1.00 87.86 ? 383 ASP B CB 383 ASP B CB 1 ATOM 4290 C CG . ASP B 2 383 ? -20.463 17.280 -2.601 1.00 87.86 ? 383 ASP B CG 383 ASP B CG 1 ATOM 4291 O OD1 . ASP B 2 383 ? -19.908 16.258 -3.058 1.00 87.86 ? 383 ASP B OD1 383 ASP B OD1 1 ATOM 4292 O OD2 . ASP B 2 383 ? -21.641 17.589 -2.883 1.00 87.86 ? 383 ASP B OD2 383 ASP B OD2 1 ATOM 4293 N N . LYS B 2 384 ? -17.580 18.844 0.635 1.00 86.51 ? 384 LYS B N 384 LYS B N 1 ATOM 4294 C CA . LYS B 2 384 ? -16.677 19.854 1.181 1.00 86.51 ? 384 LYS B CA 384 LYS B CA 1 ATOM 4295 C C . LYS B 2 384 ? -15.289 19.272 1.432 1.00 86.51 ? 384 LYS B C 384 LYS B C 1 ATOM 4296 O O . LYS B 2 384 ? -14.304 20.010 1.502 1.00 86.51 ? 384 LYS B O 384 LYS B O 1 ATOM 4297 C CB . LYS B 2 384 ? -17.244 20.436 2.477 1.00 86.51 ? 384 LYS B CB 384 LYS B CB 1 ATOM 4298 C CG . LYS B 2 384 ? -18.470 21.314 2.277 1.00 86.51 ? 384 LYS B CG 384 LYS B CG 1 ATOM 4299 C CD . LYS B 2 384 ? -18.966 21.890 3.597 1.00 86.51 ? 384 LYS B CD 384 LYS B CD 1 ATOM 4300 C CE . LYS B 2 384 ? -20.216 22.738 3.404 1.00 86.51 ? 384 LYS B CE 384 LYS B CE 1 ATOM 4301 N NZ . LYS B 2 384 ? -20.740 23.257 4.703 1.00 86.51 ? 384 LYS B NZ 384 LYS B NZ 1 ATOM 4302 N N . GLN B 2 385 ? -15.384 17.911 1.432 1.00 81.01 ? 385 GLN B N 385 GLN B N 1 ATOM 4303 C CA . GLN B 2 385 ? -14.103 17.234 1.606 1.00 81.01 ? 385 GLN B CA 385 GLN B CA 1 ATOM 4304 C C . GLN B 2 385 ? -13.412 17.011 0.264 1.00 81.01 ? 385 GLN B C 385 GLN B C 1 ATOM 4305 O O . GLN B 2 385 ? -14.040 17.124 -0.790 1.00 81.01 ? 385 GLN B O 385 GLN B O 1 ATOM 4306 C CB . GLN B 2 385 ? -14.296 15.898 2.325 1.00 81.01 ? 385 GLN B CB 385 GLN B CB 1 ATOM 4307 C CG . GLN B 2 385 ? -14.747 16.038 3.773 1.00 81.01 ? 385 GLN B CG 385 GLN B CG 1 ATOM 4308 C CD . GLN B 2 385 ? -13.652 16.566 4.680 1.00 81.01 ? 385 GLN B CD 385 GLN B CD 1 ATOM 4309 O OE1 . GLN B 2 385 ? -12.461 16.360 4.423 1.00 81.01 ? 385 GLN B OE1 385 GLN B OE1 1 ATOM 4310 N NE2 . GLN B 2 385 ? -14.045 17.250 5.749 1.00 81.01 ? 385 GLN B NE2 385 GLN B NE2 1 ATOM 4311 N N . GLY B 2 386 ? -12.210 17.159 0.237 1.00 76.31 ? 386 GLY B N 386 GLY B N 1 ATOM 4312 C CA . GLY B 2 386 ? -11.395 17.005 -0.957 1.00 76.31 ? 386 GLY B CA 386 GLY B CA 1 ATOM 4313 C C . GLY B 2 386 ? -11.629 15.689 -1.674 1.00 76.31 ? 386 GLY B C 386 GLY B C 1 ATOM 4314 O O . GLY B 2 386 ? -12.636 15.018 -1.439 1.00 76.31 ? 386 GLY B O 386 GLY B O 1 ATOM 4315 N N . VAL B 2 387 ? -10.995 15.376 -2.631 1.00 81.23 ? 387 VAL B N 387 VAL B N 1 ATOM 4316 C CA . VAL B 2 387 ? -11.146 14.234 -3.527 1.00 81.23 ? 387 VAL B CA 387 VAL B CA 1 ATOM 4317 C C . VAL B 2 387 ? -10.415 13.024 -2.950 1.00 81.23 ? 387 VAL B C 387 VAL B C 1 ATOM 4318 O O . VAL B 2 387 ? -10.353 11.968 -3.583 1.00 81.23 ? 387 VAL B O 387 VAL B O 1 ATOM 4319 C CB . VAL B 2 387 ? -10.617 14.550 -4.944 1.00 81.23 ? 387 VAL B CB 387 VAL B CB 1 ATOM 4320 C CG1 . VAL B 2 387 ? -11.478 15.618 -5.616 1.00 81.23 ? 387 VAL B CG1 387 VAL B CG1 1 ATOM 4321 C CG2 . VAL B 2 387 ? -9.158 14.998 -4.880 1.00 81.23 ? 387 VAL B CG2 387 VAL B CG2 1 ATOM 4322 N N . TYR B 2 388 ? -9.857 13.152 -1.791 1.00 87.51 ? 388 TYR B N 388 TYR B N 1 ATOM 4323 C CA . TYR B 2 388 ? -9.092 12.091 -1.147 1.00 87.51 ? 388 TYR B CA 388 TYR B CA 1 ATOM 4324 C C . TYR B 2 388 ? -10.003 11.174 -0.340 1.00 87.51 ? 388 TYR B C 388 TYR B C 1 ATOM 4325 O O . TYR B 2 388 ? -11.123 11.553 0.011 1.00 87.51 ? 388 TYR B O 388 TYR B O 1 ATOM 4326 C CB . TYR B 2 388 ? -8.010 12.683 -0.238 1.00 87.51 ? 388 TYR B CB 388 TYR B CB 1 ATOM 4327 C CG . TYR B 2 388 ? -6.909 13.392 -0.987 1.00 87.51 ? 388 TYR B CG 388 TYR B CG 1 ATOM 4328 C CD1 . TYR B 2 388 ? -5.873 12.676 -1.583 1.00 87.51 ? 388 TYR B CD1 388 TYR B CD1 1 ATOM 4329 C CD2 . TYR B 2 388 ? -6.900 14.778 -1.100 1.00 87.51 ? 388 TYR B CD2 388 TYR B CD2 1 ATOM 4330 C CE1 . TYR B 2 388 ? -4.854 13.325 -2.273 1.00 87.51 ? 388 TYR B CE1 388 TYR B CE1 1 ATOM 4331 C CE2 . TYR B 2 388 ? -5.886 15.437 -1.788 1.00 87.51 ? 388 TYR B CE2 388 TYR B CE2 1 ATOM 4332 C CZ . TYR B 2 388 ? -4.870 14.703 -2.370 1.00 87.51 ? 388 TYR B CZ 388 TYR B CZ 1 ATOM 4333 O OH . TYR B 2 388 ? -3.864 15.351 -3.052 1.00 87.51 ? 388 TYR B OH 388 TYR B OH 1 ATOM 4334 N N . PRO B 2 389 ? -9.566 9.970 -0.180 1.00 89.72 ? 389 PRO B N 389 PRO B N 1 ATOM 4335 C CA . PRO B 2 389 ? -10.355 9.050 0.642 1.00 89.72 ? 389 PRO B CA 389 PRO B CA 1 ATOM 4336 C C . PRO B 2 389 ? -10.576 9.569 2.061 1.00 89.72 ? 389 PRO B C 389 PRO B C 1 ATOM 4337 O O . PRO B 2 389 ? -9.704 10.240 2.620 1.00 89.72 ? 389 PRO B O 389 PRO B O 1 ATOM 4338 C CB . PRO B 2 389 ? -9.509 7.774 0.653 1.00 89.72 ? 389 PRO B CB 389 PRO B CB 1 ATOM 4339 C CG . PRO B 2 389 ? -8.629 7.888 -0.549 1.00 89.72 ? 389 PRO B CG 389 PRO B CG 1 ATOM 4340 C CD . PRO B 2 389 ? -8.360 9.343 -0.807 1.00 89.72 ? 389 PRO B CD 389 PRO B CD 1 ATOM 4341 N N . PHE B 2 390 ? -11.741 9.286 2.512 1.00 91.97 ? 390 PHE B N 390 PHE B N 1 ATOM 4342 C CA . PHE B 2 390 ? -12.059 9.755 3.855 1.00 91.97 ? 390 PHE B CA 390 PHE B CA 1 ATOM 4343 C C . PHE B 2 390 ? -12.789 8.676 4.646 1.00 91.97 ? 390 PHE B C 390 PHE B C 1 ATOM 4344 O O . PHE B 2 390 ? -13.377 7.763 4.064 1.00 91.97 ? 390 PHE B O 390 PHE B O 1 ATOM 4345 C CB . PHE B 2 390 ? -12.908 11.028 3.795 1.00 91.97 ? 390 PHE B CB 390 PHE B CB 1 ATOM 4346 C CG . PHE B 2 390 ? -14.272 10.820 3.194 1.00 91.97 ? 390 PHE B CG 390 PHE B CG 1 ATOM 4347 C CD1 . PHE B 2 390 ? -14.471 10.945 1.825 1.00 91.97 ? 390 PHE B CD1 390 PHE B CD1 1 ATOM 4348 C CD2 . PHE B 2 390 ? -15.357 10.499 4.000 1.00 91.97 ? 390 PHE B CD2 390 PHE B CD2 1 ATOM 4349 C CE1 . PHE B 2 390 ? -15.732 10.752 1.266 1.00 91.97 ? 390 PHE B CE1 390 PHE B CE1 1 ATOM 4350 C CE2 . PHE B 2 390 ? -16.621 10.305 3.449 1.00 91.97 ? 390 PHE B CE2 390 PHE B CE2 1 ATOM 4351 C CZ . PHE B 2 390 ? -16.806 10.433 2.082 1.00 91.97 ? 390 PHE B CZ 390 PHE B CZ 1 ATOM 4352 N N . LYS B 2 391 ? -12.667 8.767 6.032 1.00 94.22 ? 391 LYS B N 391 LYS B N 1 ATOM 4353 C CA . LYS B 2 391 ? -13.469 7.965 6.951 1.00 94.22 ? 391 LYS B CA 391 LYS B CA 1 ATOM 4354 C C . LYS B 2 391 ? -14.689 8.742 7.438 1.00 94.22 ? 391 LYS B C 391 LYS B C 1 ATOM 4355 O O . LYS B 2 391 ? -14.678 9.975 7.461 1.00 94.22 ? 391 LYS B O 391 LYS B O 1 ATOM 4356 C CB . LYS B 2 391 ? -12.626 7.512 8.144 1.00 94.22 ? 391 LYS B CB 391 LYS B CB 1 ATOM 4357 C CG . LYS B 2 391 ? -11.534 6.515 7.787 1.00 94.22 ? 391 LYS B CG 391 LYS B CG 1 ATOM 4358 C CD . LYS B 2 391 ? -10.792 6.030 9.026 1.00 94.22 ? 391 LYS B CD 391 LYS B CD 1 ATOM 4359 C CE . LYS B 2 391 ? -9.694 5.038 8.670 1.00 94.22 ? 391 LYS B CE 391 LYS B CE 1 ATOM 4360 N NZ . LYS B 2 391 ? -8.852 4.694 9.854 1.00 94.22 ? 391 LYS B NZ 391 LYS B NZ 1 ATOM 4361 N N . LEU B 2 392 ? -15.721 8.072 7.737 1.00 93.78 ? 392 LEU B N 392 LEU B N 1 ATOM 4362 C CA . LEU B 2 392 ? -16.945 8.721 8.193 1.00 93.78 ? 392 LEU B CA 392 LEU B CA 1 ATOM 4363 C C . LEU B 2 392 ? -16.688 9.543 9.452 1.00 93.78 ? 392 LEU B C 392 LEU B C 1 ATOM 4364 O O . LEU B 2 392 ? -17.307 10.591 9.651 1.00 93.78 ? 392 LEU B O 392 LEU B O 1 ATOM 4365 C CB . LEU B 2 392 ? -18.035 7.680 8.464 1.00 93.78 ? 392 LEU B CB 392 LEU B CB 1 ATOM 4366 C CG . LEU B 2 392 ? -18.590 6.947 7.242 1.00 93.78 ? 392 LEU B CG 392 LEU B CG 1 ATOM 4367 C CD1 . LEU B 2 392 ? -19.605 5.893 7.671 1.00 93.78 ? 392 LEU B CD1 392 LEU B CD1 1 ATOM 4368 C CD2 . LEU B 2 392 ? -19.218 7.935 6.264 1.00 93.78 ? 392 LEU B CD2 392 LEU B CD2 1 ATOM 4369 N N . SER B 2 393 ? -15.750 9.069 10.198 1.00 93.48 ? 393 SER B N 393 SER B N 1 ATOM 4370 C CA . SER B 2 393 ? -15.430 9.779 11.433 1.00 93.48 ? 393 SER B CA 393 SER B CA 1 ATOM 4371 C C . SER B 2 393 ? -14.914 11.184 11.145 1.00 93.48 ? 393 SER B C 393 SER B C 1 ATOM 4372 O O . SER B 2 393 ? -15.113 12.101 11.945 1.00 93.48 ? 393 SER B O 393 SER B O 1 ATOM 4373 C CB . SER B 2 393 ? -14.393 9.002 12.244 1.00 93.48 ? 393 SER B CB 393 SER B CB 1 ATOM 4374 O OG . SER B 2 393 ? -13.246 8.723 11.460 1.00 93.48 ? 393 SER B OG 393 SER B OG 1 ATOM 4375 N N . HIS B 2 394 ? -14.304 11.382 10.021 1.00 93.23 ? 394 HIS B N 394 HIS B N 1 ATOM 4376 C CA . HIS B 2 394 ? -13.733 12.670 9.641 1.00 93.23 ? 394 HIS B CA 394 HIS B CA 1 ATOM 4377 C C . HIS B 2 394 ? -14.826 13.698 9.367 1.00 93.23 ? 394 HIS B C 394 HIS B C 1 ATOM 4378 O O . HIS B 2 394 ? -14.575 14.904 9.414 1.00 93.23 ? 394 HIS B O 394 HIS B O 1 ATOM 4379 C CB . HIS B 2 394 ? -12.837 12.516 8.410 1.00 93.23 ? 394 HIS B CB 394 HIS B CB 1 ATOM 4380 C CG . HIS B 2 394 ? -11.691 11.577 8.616 1.00 93.23 ? 394 HIS B CG 394 HIS B CG 1 ATOM 4381 N ND1 . HIS B 2 394 ? -10.858 11.184 7.592 1.00 93.23 ? 394 HIS B ND1 394 HIS B ND1 1 ATOM 4382 C CD2 . HIS B 2 394 ? -11.240 10.956 9.732 1.00 93.23 ? 394 HIS B CD2 394 HIS B CD2 1 ATOM 4383 C CE1 . HIS B 2 394 ? -9.941 10.359 8.069 1.00 93.23 ? 394 HIS B CE1 394 HIS B CE1 1 ATOM 4384 N NE2 . HIS B 2 394 ? -10.151 10.204 9.366 1.00 93.23 ? 394 HIS B NE2 394 HIS B NE2 1 ATOM 4385 N N . LEU B 2 395 ? -16.018 13.248 9.136 1.00 92.48 ? 395 LEU B N 395 LEU B N 1 ATOM 4386 C CA . LEU B 2 395 ? -17.110 14.130 8.743 1.00 92.48 ? 395 LEU B CA 395 LEU B CA 1 ATOM 4387 C C . LEU B 2 395 ? -17.867 14.638 9.966 1.00 92.48 ? 395 LEU B C 395 LEU B C 1 ATOM 4388 O O . LEU B 2 395 ? -18.655 15.581 9.867 1.00 92.48 ? 395 LEU B O 395 LEU B O 1 ATOM 4389 C CB . LEU B 2 395 ? -18.072 13.405 7.798 1.00 92.48 ? 395 LEU B CB 395 LEU B CB 1 ATOM 4390 C CG . LEU B 2 395 ? -17.474 12.882 6.491 1.00 92.48 ? 395 LEU B CG 395 LEU B CG 1 ATOM 4391 C CD1 . LEU B 2 395 ? -18.503 12.052 5.732 1.00 92.48 ? 395 LEU B CD1 395 LEU B CD1 1 ATOM 4392 C CD2 . LEU B 2 395 ? -16.972 14.038 5.632 1.00 92.48 ? 395 LEU B CD2 395 LEU B CD2 1 ATOM 4393 N N . SER B 2 396 ? -17.553 14.066 11.028 1.00 92.37 ? 396 SER B N 396 SER B N 1 ATOM 4394 C CA . SER B 2 396 ? -18.252 14.451 12.250 1.00 92.37 ? 396 SER B CA 396 SER B CA 1 ATOM 4395 C C . SER B 2 396 ? -17.768 15.804 12.760 1.00 92.37 ? 396 SER B C 396 SER B C 1 ATOM 4396 O O . SER B 2 396 ? -16.594 16.147 12.609 1.00 92.37 ? 396 SER B O 396 SER B O 1 ATOM 4397 C CB . SER B 2 396 ? -18.061 13.390 13.334 1.00 92.37 ? 396 SER B CB 396 SER B CB 1 ATOM 4398 O OG . SER B 2 396 ? -18.598 13.831 14.569 1.00 92.37 ? 396 SER B OG 396 SER B OG 1 ATOM 4399 N N . SER B 2 397 ? -18.615 16.540 13.339 1.00 89.46 ? 397 SER B N 397 SER B N 1 ATOM 4400 C CA . SER B 2 397 ? -18.269 17.837 13.910 1.00 89.46 ? 397 SER B CA 397 SER B CA 1 ATOM 4401 C C . SER B 2 397 ? -17.398 17.680 15.152 1.00 89.46 ? 397 SER B C 397 SER B C 1 ATOM 4402 O O . SER B 2 397 ? -16.731 18.628 15.572 1.00 89.46 ? 397 SER B O 397 SER B O 1 ATOM 4403 C CB . SER B 2 397 ? -19.534 18.622 14.261 1.00 89.46 ? 397 SER B CB 397 SER B CB 1 ATOM 4404 O OG . SER B 2 397 ? -20.354 17.884 15.150 1.00 89.46 ? 397 SER B OG 397 SER B OG 1 ATOM 4405 N N . ASN B 2 398 ? -17.385 16.505 15.721 1.00 88.37 ? 398 ASN B N 398 ASN B N 1 ATOM 4406 C CA . ASN B 2 398 ? -16.616 16.224 16.928 1.00 88.37 ? 398 ASN B CA 398 ASN B CA 1 ATOM 4407 C C . ASN B 2 398 ? -15.181 15.821 16.598 1.00 88.37 ? 398 ASN B C 398 ASN B C 1 ATOM 4408 O O . ASN B 2 398 ? -14.379 15.570 17.500 1.00 88.37 ? 398 ASN B O 398 ASN B O 1 ATOM 4409 C CB . ASN B 2 398 ? -17.297 15.132 17.756 1.00 88.37 ? 398 ASN B CB 398 ASN B CB 1 ATOM 4410 C CG . ASN B 2 398 ? -18.655 15.557 18.279 1.00 88.37 ? 398 ASN B CG 398 ASN B CG 1 ATOM 4411 O OD1 . ASN B 2 398 ? -18.821 16.674 18.775 1.00 88.37 ? 398 ASN B OD1 398 ASN B OD1 1 ATOM 4412 N ND2 . ASN B 2 398 ? -19.637 14.669 18.169 1.00 88.37 ? 398 ASN B ND2 398 ASN B ND2 1 ATOM 4413 N N . PHE B 2 399 ? -14.827 15.670 15.354 1.00 88.57 ? 399 PHE B N 399 PHE B N 1 ATOM 4414 C CA . PHE B 2 399 ? -13.490 15.409 14.835 1.00 88.57 ? 399 PHE B CA 399 PHE B CA 1 ATOM 4415 C C . PHE B 2 399 ? -12.867 16.683 14.278 1.00 88.57 ? 399 PHE B C 399 PHE B C 1 ATOM 4416 O O . PHE B 2 399 ? -13.524 17.439 13.558 1.00 88.57 ? 399 PHE B O 399 PHE B O 1 ATOM 4417 C CB . PHE B 2 399 ? -13.536 14.329 13.749 1.00 88.57 ? 399 PHE B CB 399 PHE B CB 1 ATOM 4418 C CG . PHE B 2 399 ? -12.184 13.967 13.196 1.00 88.57 ? 399 PHE B CG 399 PHE B CG 1 ATOM 4419 C CD1 . PHE B 2 399 ? -11.689 14.601 12.062 1.00 88.57 ? 399 PHE B CD1 399 PHE B CD1 1 ATOM 4420 C CD2 . PHE B 2 399 ? -11.407 12.994 13.810 1.00 88.57 ? 399 PHE B CD2 399 PHE B CD2 1 ATOM 4421 C CE1 . PHE B 2 399 ? -10.438 14.268 11.548 1.00 88.57 ? 399 PHE B CE1 399 PHE B CE1 1 ATOM 4422 C CE2 . PHE B 2 399 ? -10.156 12.656 13.302 1.00 88.57 ? 399 PHE B CE2 399 PHE B CE2 1 ATOM 4423 C CZ . PHE B 2 399 ? -9.674 13.294 12.170 1.00 88.57 ? 399 PHE B CZ 399 PHE B CZ 1 ATOM 4424 N N . PRO B 2 400 ? -11.480 16.830 14.780 1.00 86.10 ? 400 PRO B N 400 PRO B N 1 ATOM 4425 C CA . PRO B 2 400 ? -10.407 16.043 15.393 1.00 86.10 ? 400 PRO B CA 400 PRO B CA 1 ATOM 4426 C C . PRO B 2 400 ? -10.454 16.069 16.919 1.00 86.10 ? 400 PRO B C 400 PRO B C 1 ATOM 4427 O O . PRO B 2 400 ? -11.083 16.952 17.506 1.00 86.10 ? 400 PRO B O 400 PRO B O 1 ATOM 4428 C CB . PRO B 2 400 ? -9.135 16.719 14.875 1.00 86.10 ? 400 PRO B CB 400 PRO B CB 1 ATOM 4429 C CG . PRO B 2 400 ? -9.523 18.144 14.650 1.00 86.10 ? 400 PRO B CG 400 PRO B CG 1 ATOM 4430 C CD . PRO B 2 400 ? -10.978 18.190 14.281 1.00 86.10 ? 400 PRO B CD 400 PRO B CD 1 ATOM 4431 N N . PHE B 2 401 ? -9.830 15.030 17.598 1.00 79.19 ? 401 PHE B N 401 PHE B N 1 ATOM 4432 C CA . PHE B 2 401 ? -9.780 14.891 19.049 1.00 79.19 ? 401 PHE B CA 401 PHE B CA 1 ATOM 4433 C C . PHE B 2 401 ? -8.491 15.482 19.606 1.00 79.19 ? 401 PHE B C 401 PHE B C 1 ATOM 4434 O O . PHE B 2 401 ? -7.420 15.313 19.020 1.00 79.19 ? 401 PHE B O 401 PHE B O 1 ATOM 4435 C CB . PHE B 2 401 ? -9.900 13.418 19.453 1.00 79.19 ? 401 PHE B CB 401 PHE B CB 1 ATOM 4436 C CG . PHE B 2 401 ? -11.198 12.779 19.041 1.00 79.19 ? 401 PHE B CG 401 PHE B CG 1 ATOM 4437 C CD1 . PHE B 2 401 ? -12.330 12.894 19.839 1.00 79.19 ? 401 PHE B CD1 401 PHE B CD1 1 ATOM 4438 C CD2 . PHE B 2 401 ? -11.287 12.062 17.855 1.00 79.19 ? 401 PHE B CD2 401 PHE B CD2 1 ATOM 4439 C CE1 . PHE B 2 401 ? -13.533 12.303 19.461 1.00 79.19 ? 401 PHE B CE1 401 PHE B CE1 1 ATOM 4440 C CE2 . PHE B 2 401 ? -12.486 11.469 17.470 1.00 79.19 ? 401 PHE B CE2 401 PHE B CE2 1 ATOM 4441 C CZ . PHE B 2 401 ? -13.608 11.590 18.274 1.00 79.19 ? 401 PHE B CZ 401 PHE B CZ 1 ATOM 4442 N N . VAL B 2 402 ? -8.601 16.311 20.598 1.00 69.81 ? 402 VAL B N 402 VAL B N 1 ATOM 4443 C CA . VAL B 2 402 ? -7.396 16.834 21.235 1.00 69.81 ? 402 VAL B CA 402 VAL B CA 1 ATOM 4444 C C . VAL B 2 402 ? -7.019 15.957 22.427 1.00 69.81 ? 402 VAL B C 402 VAL B C 1 ATOM 4445 O O . VAL B 2 402 ? -5.847 15.625 22.615 1.00 69.81 ? 402 VAL B O 402 VAL B O 1 ATOM 4446 C CB . VAL B 2 402 ? -7.584 18.299 21.689 1.00 69.81 ? 402 VAL B CB 402 VAL B CB 1 ATOM 4447 C CG1 . VAL B 2 402 ? -6.320 18.819 22.371 1.00 69.81 ? 402 VAL B CG1 402 VAL B CG1 1 ATOM 4448 C CG2 . VAL B 2 402 ? -7.956 19.182 20.500 1.00 69.81 ? 402 VAL B CG2 402 VAL B CG2 1 ATOM 4449 N N . HIS B 2 403 ? -8.068 15.382 23.154 1.00 68.84 ? 403 HIS B N 403 HIS B N 1 ATOM 4450 C CA . HIS B 2 403 ? -7.874 14.524 24.318 1.00 68.84 ? 403 HIS B CA 403 HIS B CA 1 ATOM 4451 C C . HIS B 2 403 ? -8.776 13.295 24.252 1.00 68.84 ? 403 HIS B C 403 HIS B C 1 ATOM 4452 O O . HIS B 2 403 ? -9.799 13.307 23.564 1.00 68.84 ? 403 HIS B O 403 HIS B O 1 ATOM 4453 C CB . HIS B 2 403 ? -8.140 15.302 25.608 1.00 68.84 ? 403 HIS B CB 403 HIS B CB 1 ATOM 4454 C CG . HIS B 2 403 ? -7.246 16.487 25.788 1.00 68.84 ? 403 HIS B CG 403 HIS B CG 1 ATOM 4455 N ND1 . HIS B 2 403 ? -5.874 16.382 25.851 1.00 68.84 ? 403 HIS B ND1 403 HIS B ND1 1 ATOM 4456 C CD2 . HIS B 2 403 ? -7.532 17.805 25.915 1.00 68.84 ? 403 HIS B CD2 403 HIS B CD2 1 ATOM 4457 C CE1 . HIS B 2 403 ? -5.352 17.587 26.011 1.00 68.84 ? 403 HIS B CE1 403 HIS B CE1 1 ATOM 4458 N NE2 . HIS B 2 403 ? -6.337 18.468 26.053 1.00 68.84 ? 403 HIS B NE2 403 HIS B NE2 1 ATOM 4459 N N . GLU B 2 404 ? -8.184 12.107 24.795 1.00 70.57 ? 404 GLU B N 404 GLU B N 1 ATOM 4460 C CA . GLU B 2 404 ? -8.943 10.864 24.891 1.00 70.57 ? 404 GLU B CA 404 GLU B CA 1 ATOM 4461 C C . GLU B 2 404 ? -10.140 11.020 25.825 1.00 70.57 ? 404 GLU B C 404 GLU B C 1 ATOM 4462 O O . GLU B 2 404 ? -10.047 10.721 27.018 1.00 70.57 ? 404 GLU B O 404 GLU B O 1 ATOM 4463 C CB . GLU B 2 404 ? -8.046 9.721 25.372 1.00 70.57 ? 404 GLU B CB 404 GLU B CB 1 ATOM 4464 C CG . GLU B 2 404 ? -7.018 9.272 24.344 1.00 70.57 ? 404 GLU B CG 404 GLU B CG 1 ATOM 4465 C CD . GLU B 2 404 ? -6.135 8.136 24.835 1.00 70.57 ? 404 GLU B CD 404 GLU B CD 1 ATOM 4466 O OE1 . GLU B 2 404 ? -5.241 7.692 24.080 1.00 70.57 ? 404 GLU B OE1 404 GLU B OE1 1 ATOM 4467 O OE2 . GLU B 2 404 ? -6.340 7.685 25.984 1.00 70.57 ? 404 GLU B OE2 404 GLU B OE2 1 ATOM 4468 N N . ASN B 2 405 ? -11.118 11.923 25.465 1.00 78.66 ? 405 ASN B N 405 ASN B N 1 ATOM 4469 C CA . ASN B 2 405 ? -12.311 12.059 26.295 1.00 78.66 ? 405 ASN B CA 405 ASN B CA 1 ATOM 4470 C C . ASN B 2 405 ? -13.404 11.083 25.868 1.00 78.66 ? 405 ASN B C 405 ASN B C 1 ATOM 4471 O O . ASN B 2 405 ? -13.758 11.016 24.690 1.00 78.66 ? 405 ASN B O 405 ASN B O 1 ATOM 4472 C CB . ASN B 2 405 ? -12.836 13.495 26.250 1.00 78.66 ? 405 ASN B CB 405 ASN B CB 1 ATOM 4473 C CG . ASN B 2 405 ? -12.013 14.444 27.098 1.00 78.66 ? 405 ASN B CG 405 ASN B CG 1 ATOM 4474 O OD1 . ASN B 2 405 ? -11.131 14.019 27.849 1.00 78.66 ? 405 ASN B OD1 405 ASN B OD1 1 ATOM 4475 N ND2 . ASN B 2 405 ? -12.293 15.737 26.985 1.00 78.66 ? 405 ASN B ND2 405 ASN B ND2 1 ATOM 4476 N N . GLU B 2 406 ? -13.797 10.204 26.763 1.00 83.02 ? 406 GLU B N 406 GLU B N 1 ATOM 4477 C CA . GLU B 2 406 ? -14.814 9.177 26.553 1.00 83.02 ? 406 GLU B CA 406 GLU B CA 1 ATOM 4478 C C . GLU B 2 406 ? -16.125 9.790 26.069 1.00 83.02 ? 406 GLU B C 406 GLU B C 1 ATOM 4479 O O . GLU B 2 406 ? -16.832 9.192 25.255 1.00 83.02 ? 406 GLU B O 406 GLU B O 1 ATOM 4480 C CB . GLU B 2 406 ? -15.048 8.382 27.840 1.00 83.02 ? 406 GLU B CB 406 GLU B CB 1 ATOM 4481 C CG . GLU B 2 406 ? -15.886 7.127 27.643 1.00 83.02 ? 406 GLU B CG 406 GLU B CG 1 ATOM 4482 C CD . GLU B 2 406 ? -15.216 6.091 26.754 1.00 83.02 ? 406 GLU B CD 406 GLU B CD 1 ATOM 4483 O OE1 . GLU B 2 406 ? -15.924 5.222 26.195 1.00 83.02 ? 406 GLU B OE1 406 GLU B OE1 1 ATOM 4484 O OE2 . GLU B 2 406 ? -13.974 6.149 26.615 1.00 83.02 ? 406 GLU B OE2 406 GLU B OE2 1 ATOM 4485 N N . GLU B 2 407 ? -16.490 10.951 26.493 1.00 86.80 ? 407 GLU B N 407 GLU B N 1 ATOM 4486 C CA . GLU B 2 407 ? -17.730 11.611 26.099 1.00 86.80 ? 407 GLU B CA 407 GLU B CA 1 ATOM 4487 C C . GLU B 2 407 ? -17.711 11.984 24.619 1.00 86.80 ? 407 GLU B C 407 GLU B C 1 ATOM 4488 O O . GLU B 2 407 ? -18.706 11.799 23.914 1.00 86.80 ? 407 GLU B O 407 GLU B O 1 ATOM 4489 C CB . GLU B 2 407 ? -17.970 12.859 26.953 1.00 86.80 ? 407 GLU B CB 407 GLU B CB 1 ATOM 4490 C CG . GLU B 2 407 ? -18.315 12.555 28.403 1.00 86.80 ? 407 GLU B CG 407 GLU B CG 1 ATOM 4491 C CD . GLU B 2 407 ? -18.542 13.804 29.241 1.00 86.80 ? 407 GLU B CD 407 GLU B CD 1 ATOM 4492 O OE1 . GLU B 2 407 ? -18.801 13.678 30.459 1.00 86.80 ? 407 GLU B OE1 407 GLU B OE1 1 ATOM 4493 O OE2 . GLU B 2 407 ? -18.460 14.916 28.674 1.00 86.80 ? 407 GLU B OE2 407 GLU B OE2 1 ATOM 4494 N N . GLU B 2 408 ? -16.581 12.492 24.183 1.00 86.96 ? 408 GLU B N 408 GLU B N 1 ATOM 4495 C CA . GLU B 2 408 ? -16.421 12.863 22.780 1.00 86.96 ? 408 GLU B CA 408 GLU B CA 1 ATOM 4496 C C . GLU B 2 408 ? -16.497 11.637 21.874 1.00 86.96 ? 408 GLU B C 408 GLU B C 1 ATOM 4497 O O . GLU B 2 408 ? -17.085 11.694 20.792 1.00 86.96 ? 408 GLU B O 408 GLU B O 1 ATOM 4498 C CB . GLU B 2 408 ? -15.095 13.596 22.564 1.00 86.96 ? 408 GLU B CB 408 GLU B CB 1 ATOM 4499 C CG . GLU B 2 408 ? -15.064 14.998 23.154 1.00 86.96 ? 408 GLU B CG 408 GLU B CG 1 ATOM 4500 C CD . GLU B 2 408 ? -13.731 15.702 22.959 1.00 86.96 ? 408 GLU B CD 408 GLU B CD 1 ATOM 4501 O OE1 . GLU B 2 408 ? -13.590 16.867 23.395 1.00 86.96 ? 408 GLU B OE1 408 GLU B OE1 1 ATOM 4502 O OE2 . GLU B 2 408 ? -12.819 15.083 22.366 1.00 86.96 ? 408 GLU B OE2 408 GLU B OE2 1 ATOM 4503 N N . LEU B 2 409 ? -15.972 10.560 22.437 1.00 86.96 ? 409 LEU B N 409 LEU B N 1 ATOM 4504 C CA . LEU B 2 409 ? -15.984 9.308 21.689 1.00 86.96 ? 409 LEU B CA 409 LEU B CA 1 ATOM 4505 C C . LEU B 2 409 ? -17.405 8.772 21.550 1.00 86.96 ? 409 LEU B C 409 LEU B C 1 ATOM 4506 O O . LEU B 2 409 ? -17.789 8.290 20.482 1.00 86.96 ? 409 LEU B O 409 LEU B O 1 ATOM 4507 C CB . LEU B 2 409 ? -15.098 8.265 22.376 1.00 86.96 ? 409 LEU B CB 409 LEU B CB 1 ATOM 4508 C CG . LEU B 2 409 ? -14.832 6.980 21.590 1.00 86.96 ? 409 LEU B CG 409 LEU B CG 1 ATOM 4509 C CD1 . LEU B 2 409 ? -14.018 7.283 20.337 1.00 86.96 ? 409 LEU B CD1 409 LEU B CD1 1 ATOM 4510 C CD2 . LEU B 2 409 ? -14.115 5.957 22.466 1.00 86.96 ? 409 LEU B CD2 409 LEU B CD2 1 ATOM 4511 N N . GLN B 2 410 ? -18.187 8.897 22.564 1.00 89.68 ? 410 GLN B N 410 GLN B N 1 ATOM 4512 C CA . GLN B 2 410 ? -19.573 8.443 22.533 1.00 89.68 ? 410 GLN B CA 410 GLN B CA 1 ATOM 4513 C C . GLN B 2 410 ? -20.408 9.290 21.576 1.00 89.68 ? 410 GLN B C 410 GLN B C 1 ATOM 4514 O O . GLN B 2 410 ? -21.268 8.766 20.865 1.00 89.68 ? 410 GLN B O 410 GLN B O 1 ATOM 4515 C CB . GLN B 2 410 ? -20.183 8.481 23.935 1.00 89.68 ? 410 GLN B CB 410 GLN B CB 1 ATOM 4516 C CG . GLN B 2 410 ? -19.645 7.405 24.869 1.00 89.68 ? 410 GLN B CG 410 GLN B CG 1 ATOM 4517 C CD . GLN B 2 410 ? -19.895 6.000 24.351 1.00 89.68 ? 410 GLN B CD 410 GLN B CD 1 ATOM 4518 O OE1 . GLN B 2 410 ? -20.840 5.763 23.593 1.00 89.68 ? 410 GLN B OE1 410 GLN B OE1 1 ATOM 4519 N NE2 . GLN B 2 410 ? -19.050 5.060 24.758 1.00 89.68 ? 410 GLN B NE2 410 GLN B NE2 1 ATOM 4520 N N . SER B 2 411 ? -20.170 10.550 21.556 1.00 91.13 ? 411 SER B N 411 SER B N 1 ATOM 4521 C CA . SER B 2 411 ? -20.863 11.440 20.630 1.00 91.13 ? 411 SER B CA 411 SER B CA 1 ATOM 4522 C C . SER B 2 411 ? -20.525 11.103 19.182 1.00 91.13 ? 411 SER B C 411 SER B C 1 ATOM 4523 O O . SER B 2 411 ? -21.397 11.135 18.311 1.00 91.13 ? 411 SER B O 411 SER B O 1 ATOM 4524 C CB . SER B 2 411 ? -20.505 12.898 20.919 1.00 91.13 ? 411 SER B CB 411 SER B CB 1 ATOM 4525 O OG . SER B 2 411 ? -19.121 13.126 20.717 1.00 91.13 ? 411 SER B OG 411 SER B OG 1 ATOM 4526 N N . LEU B 2 412 ? -19.306 10.828 18.993 1.00 92.03 ? 412 LEU B N 412 LEU B N 1 ATOM 4527 C CA . LEU B 2 412 ? -18.872 10.430 17.658 1.00 92.03 ? 412 LEU B CA 412 LEU B CA 1 ATOM 4528 C C . LEU B 2 412 ? -19.545 9.129 17.232 1.00 92.03 ? 412 LEU B C 412 LEU B C 1 ATOM 4529 O O . LEU B 2 412 ? -20.002 9.006 16.093 1.00 92.03 ? 412 LEU B O 412 LEU B O 1 ATOM 4530 C CB . LEU B 2 412 ? -17.350 10.267 17.616 1.00 92.03 ? 412 LEU B CB 412 LEU B CB 1 ATOM 4531 C CG . LEU B 2 412 ? -16.745 9.900 16.260 1.00 92.03 ? 412 LEU B CG 412 LEU B CG 1 ATOM 4532 C CD1 . LEU B 2 412 ? -16.887 11.063 15.284 1.00 92.03 ? 412 LEU B CD1 412 LEU B CD1 1 ATOM 4533 C CD2 . LEU B 2 412 ? -15.281 9.503 16.417 1.00 92.03 ? 412 LEU B CD2 412 LEU B CD2 1 ATOM 4534 N N . LYS B 2 413 ? -19.655 8.182 18.123 1.00 92.18 ? 413 LYS B N 413 LYS B N 1 ATOM 4535 C CA . LYS B 2 413 ? -20.316 6.909 17.847 1.00 92.18 ? 413 LYS B CA 413 LYS B CA 1 ATOM 4536 C C . LYS B 2 413 ? -21.772 7.122 17.444 1.00 92.18 ? 413 LYS B C 413 LYS B C 1 ATOM 4537 O O . LYS B 2 413 ? -22.275 6.456 16.537 1.00 92.18 ? 413 LYS B O 413 LYS B O 1 ATOM 4538 C CB . LYS B 2 413 ? -20.238 5.989 19.066 1.00 92.18 ? 413 LYS B CB 413 LYS B CB 1 ATOM 4539 C CG . LYS B 2 413 ? -18.870 5.358 19.279 1.00 92.18 ? 413 LYS B CG 413 LYS B CG 1 ATOM 4540 C CD . LYS B 2 413 ? -18.881 4.381 20.448 1.00 92.18 ? 413 LYS B CD 413 LYS B CD 1 ATOM 4541 C CE . LYS B 2 413 ? -17.507 3.767 20.677 1.00 92.18 ? 413 LYS B CE 413 LYS B CE 1 ATOM 4542 N NZ . LYS B 2 413 ? -17.507 2.826 21.837 1.00 92.18 ? 413 LYS B NZ 413 LYS B NZ 1 ATOM 4543 N N . LYS B 2 414 ? -22.397 8.049 18.073 1.00 92.11 ? 414 LYS B N 414 LYS B N 1 ATOM 4544 C CA . LYS B 2 414 ? -23.787 8.364 17.759 1.00 92.11 ? 414 LYS B CA 414 LYS B CA 1 ATOM 4545 C C . LYS B 2 414 ? -23.912 8.973 16.366 1.00 92.11 ? 414 LYS B C 414 LYS B C 1 ATOM 4546 O O . LYS B 2 414 ? -24.819 8.622 15.608 1.00 92.11 ? 414 LYS B O 414 LYS B O 1 ATOM 4547 C CB . LYS B 2 414 ? -24.371 9.318 18.802 1.00 92.11 ? 414 LYS B CB 414 LYS B CB 1 ATOM 4548 C CG . LYS B 2 414 ? -25.864 9.567 18.648 1.00 92.11 ? 414 LYS B CG 414 LYS B CG 1 ATOM 4549 C CD . LYS B 2 414 ? -26.391 10.498 19.732 1.00 92.11 ? 414 LYS B CD 414 LYS B CD 1 ATOM 4550 C CE . LYS B 2 414 ? -27.861 10.831 19.518 1.00 92.11 ? 414 LYS B CE 414 LYS B CE 1 ATOM 4551 N NZ . LYS B 2 414 ? -28.384 11.740 20.582 1.00 92.11 ? 414 LYS B NZ 414 LYS B NZ 1 ATOM 4552 N N . ASP B 2 415 ? -22.997 9.852 16.024 1.00 92.63 ? 415 ASP B N 415 ASP B N 1 ATOM 4553 C CA . ASP B 2 415 ? -22.993 10.479 14.706 1.00 92.63 ? 415 ASP B CA 415 ASP B CA 1 ATOM 4554 C C . ASP B 2 415 ? -22.749 9.447 13.607 1.00 92.63 ? 415 ASP B C 415 ASP B C 1 ATOM 4555 O O . ASP B 2 415 ? -23.358 9.517 12.537 1.00 92.63 ? 415 ASP B O 415 ASP B O 1 ATOM 4556 C CB . ASP B 2 415 ? -21.931 11.579 14.638 1.00 92.63 ? 415 ASP B CB 415 ASP B CB 1 ATOM 4557 C CG . ASP B 2 415 ? -22.287 12.799 15.471 1.00 92.63 ? 415 ASP B CG 415 ASP B CG 1 ATOM 4558 O OD1 . ASP B 2 415 ? -23.457 12.931 15.889 1.00 92.63 ? 415 ASP B OD1 415 ASP B OD1 1 ATOM 4559 O OD2 . ASP B 2 415 ? -21.390 13.636 15.707 1.00 92.63 ? 415 ASP B OD2 415 ASP B OD2 1 ATOM 4560 N N . LEU B 2 416 ? -21.922 8.488 13.907 1.00 93.12 ? 416 LEU B N 416 LEU B N 1 ATOM 4561 C CA . LEU B 2 416 ? -21.522 7.486 12.924 1.00 93.12 ? 416 LEU B CA 416 LEU B CA 1 ATOM 4562 C C . LEU B 2 416 ? -22.704 6.606 12.534 1.00 93.12 ? 416 LEU B C 416 LEU B C 1 ATOM 4563 O O . LEU B 2 416 ? -22.811 6.178 11.382 1.00 93.12 ? 416 LEU B O 416 LEU B O 1 ATOM 4564 C CB . LEU B 2 416 ? -20.385 6.620 13.474 1.00 93.12 ? 416 LEU B CB 416 LEU B CB 1 ATOM 4565 C CG . LEU B 2 416 ? -19.006 7.276 13.543 1.00 93.12 ? 416 LEU B CG 416 LEU B CG 1 ATOM 4566 C CD1 . LEU B 2 416 ? -17.995 6.321 14.169 1.00 93.12 ? 416 LEU B CD1 416 LEU B CD1 1 ATOM 4567 C CD2 . LEU B 2 416 ? -18.550 7.712 12.155 1.00 93.12 ? 416 LEU B CD2 416 LEU B CD2 1 ATOM 4568 N N . LYS B 2 417 ? -23.620 6.343 13.443 1.00 91.89 ? 417 LYS B N 417 LYS B N 1 ATOM 4569 C CA . LYS B 2 417 ? -24.795 5.527 13.152 1.00 91.89 ? 417 LYS B CA 417 LYS B CA 1 ATOM 4570 C C . LYS B 2 417 ? -25.669 6.182 12.086 1.00 91.89 ? 417 LYS B C 417 LYS B C 1 ATOM 4571 O O . LYS B 2 417 ? -26.108 5.521 11.143 1.00 91.89 ? 417 LYS B O 417 LYS B O 1 ATOM 4572 C CB . LYS B 2 417 ? -25.610 5.285 14.423 1.00 91.89 ? 417 LYS B CB 417 LYS B CB 1 ATOM 4573 C CG . LYS B 2 417 ? -24.948 4.338 15.412 1.00 91.89 ? 417 LYS B CG 417 LYS B CG 1 ATOM 4574 C CD . LYS B 2 417 ? -25.837 4.083 16.623 1.00 91.89 ? 417 LYS B CD 417 LYS B CD 1 ATOM 4575 C CE . LYS B 2 417 ? -25.149 3.187 17.644 1.00 91.89 ? 417 LYS B CE 417 LYS B CE 1 ATOM 4576 N NZ . LYS B 2 417 ? -26.002 2.966 18.850 1.00 91.89 ? 417 LYS B NZ 417 LYS B NZ 1 ATOM 4577 N N . SER B 2 418 ? -25.834 7.502 12.240 1.00 91.83 ? 418 SER B N 418 SER B N 1 ATOM 4578 C CA . SER B 2 418 ? -26.624 8.257 11.273 1.00 91.83 ? 418 SER B CA 418 SER B CA 1 ATOM 4579 C C . SER B 2 418 ? -25.897 8.377 9.938 1.00 91.83 ? 418 SER B C 418 SER B C 1 ATOM 4580 O O . SER B 2 418 ? -26.509 8.239 8.877 1.00 91.83 ? 418 SER B O 418 SER B O 1 ATOM 4581 C CB . SER B 2 418 ? -26.947 9.650 11.814 1.00 91.83 ? 418 SER B CB 418 SER B CB 1 ATOM 4582 O OG . SER B 2 418 ? -27.677 10.403 10.861 1.00 91.83 ? 418 SER B OG 418 SER B OG 1 ATOM 4583 N N . PHE B 2 419 ? -24.618 8.603 9.964 1.00 94.05 ? 419 PHE B N 419 PHE B N 1 ATOM 4584 C CA . PHE B 2 419 ? -23.813 8.731 8.755 1.00 94.05 ? 419 PHE B CA 419 PHE B CA 1 ATOM 4585 C C . PHE B 2 419 ? -23.833 7.437 7.950 1.00 94.05 ? 419 PHE B C 419 PHE B C 1 ATOM 4586 O O . PHE B 2 419 ? -23.860 7.467 6.718 1.00 94.05 ? 419 PHE B O 419 PHE B O 1 ATOM 4587 C CB . PHE B 2 419 ? -22.370 9.108 9.106 1.00 94.05 ? 419 PHE B CB 419 PHE B CB 1 ATOM 4588 C CG . PHE B 2 419 ? -22.219 10.510 9.631 1.00 94.05 ? 419 PHE B CG 419 PHE B CG 1 ATOM 4589 C CD1 . PHE B 2 419 ? -23.240 11.439 9.475 1.00 94.05 ? 419 PHE B CD1 419 PHE B CD1 1 ATOM 4590 C CD2 . PHE B 2 419 ? -21.056 10.899 10.282 1.00 94.05 ? 419 PHE B CD2 419 PHE B CD2 1 ATOM 4591 C CE1 . PHE B 2 419 ? -23.104 12.738 9.959 1.00 94.05 ? 419 PHE B CE1 419 PHE B CE1 1 ATOM 4592 C CE2 . PHE B 2 419 ? -20.912 12.195 10.769 1.00 94.05 ? 419 PHE B CE2 419 PHE B CE2 1 ATOM 4593 C CZ . PHE B 2 419 ? -21.936 13.113 10.606 1.00 94.05 ? 419 PHE B CZ 419 PHE B CZ 1 ATOM 4594 N N . ARG B 2 420 ? -23.962 6.405 8.596 1.00 91.23 ? 420 ARG B N 420 ARG B N 1 ATOM 4595 C CA . ARG B 2 420 ? -23.948 5.108 7.928 1.00 91.23 ? 420 ARG B CA 420 ARG B CA 1 ATOM 4596 C C . ARG B 2 420 ? -25.206 4.911 7.088 1.00 91.23 ? 420 ARG B C 420 ARG B C 1 ATOM 4597 O O . ARG B 2 420 ? -25.141 4.374 5.980 1.00 91.23 ? 420 ARG B O 420 ARG B O 1 ATOM 4598 C CB . ARG B 2 420 ? -23.820 3.977 8.951 1.00 91.23 ? 420 ARG B CB 420 ARG B CB 1 ATOM 4599 C CG . ARG B 2 420 ? -22.401 3.753 9.448 1.00 91.23 ? 420 ARG B CG 420 ARG B CG 1 ATOM 4600 C CD . ARG B 2 420 ? -21.579 2.938 8.459 1.00 91.23 ? 420 ARG B CD 420 ARG B CD 1 ATOM 4601 N NE . ARG B 2 420 ? -20.236 2.670 8.965 1.00 91.23 ? 420 ARG B NE 420 ARG B NE 1 ATOM 4602 C CZ . ARG B 2 420 ? -19.327 1.924 8.345 1.00 91.23 ? 420 ARG B CZ 420 ARG B CZ 1 ATOM 4603 N NH1 . ARG B 2 420 ? -19.600 1.352 7.178 1.00 91.23 ? 420 ARG B NH1 420 ARG B NH1 1 ATOM 4604 N NH2 . ARG B 2 420 ? -18.135 1.746 8.896 1.00 91.23 ? 420 ARG B NH2 420 ARG B NH2 1 ATOM 4605 N N . LEU B 2 421 ? -26.220 5.213 7.710 1.00 91.47 ? 421 LEU B N 421 LEU B N 1 ATOM 4606 C CA . LEU B 2 421 ? -27.482 5.128 6.982 1.00 91.47 ? 421 LEU B CA 421 LEU B CA 1 ATOM 4607 C C . LEU B 2 421 ? -27.443 5.991 5.725 1.00 91.47 ? 421 LEU B C 421 LEU B C 1 ATOM 4608 O O . LEU B 2 421 ? -27.851 5.547 4.650 1.00 91.47 ? 421 LEU B O 421 LEU B O 1 ATOM 4609 C CB . LEU B 2 421 ? -28.647 5.559 7.876 1.00 91.47 ? 421 LEU B CB 421 LEU B CB 1 ATOM 4610 C CG . LEU B 2 421 ? -30.041 5.499 7.249 1.00 91.47 ? 421 LEU B CG 421 LEU B CG 1 ATOM 4611 C CD1 . LEU B 2 421 ? -30.406 4.058 6.906 1.00 91.47 ? 421 LEU B CD1 421 LEU B CD1 1 ATOM 4612 C CD2 . LEU B 2 421 ? -31.076 6.109 8.187 1.00 91.47 ? 421 LEU B CD2 421 LEU B CD2 1 ATOM 4613 N N . GLY B 2 422 ? -26.911 7.144 5.867 1.00 92.56 ? 422 GLY B N 422 GLY B N 1 ATOM 4614 C CA . GLY B 2 422 ? -26.782 8.034 4.724 1.00 92.56 ? 422 GLY B CA 422 GLY B CA 1 ATOM 4615 C C . GLY B 2 422 ? -25.790 7.537 3.690 1.00 92.56 ? 422 GLY B C 422 GLY B C 1 ATOM 4616 O O . GLY B 2 422 ? -26.034 7.643 2.486 1.00 92.56 ? 422 GLY B O 422 GLY B O 1 ATOM 4617 N N . MET B 2 423 ? -24.717 6.982 4.190 1.00 93.52 ? 423 MET B N 423 MET B N 1 ATOM 4618 C CA . MET B 2 423 ? -23.662 6.472 3.318 1.00 93.52 ? 423 MET B CA 423 MET B CA 1 ATOM 4619 C C . MET B 2 423 ? -24.162 5.292 2.492 1.00 93.52 ? 423 MET B C 423 MET B C 1 ATOM 4620 O O . MET B 2 423 ? -23.700 5.074 1.371 1.00 93.52 ? 423 MET B O 423 MET B O 1 ATOM 4621 C CB . MET B 2 423 ? -22.440 6.056 4.138 1.00 93.52 ? 423 MET B CB 423 MET B CB 1 ATOM 4622 C CG . MET B 2 423 ? -21.210 5.756 3.297 1.00 93.52 ? 423 MET B CG 423 MET B CG 1 ATOM 4623 S SD . MET B 2 423 ? -20.694 7.187 2.270 1.00 93.52 ? 423 MET B SD 423 MET B SD 1 ATOM 4624 C CE . MET B 2 423 ? -19.876 8.205 3.529 1.00 93.52 ? 423 MET B CE 423 MET B CE 1 ATOM 4625 N N . SER B 2 424 ? -25.064 4.480 2.996 1.00 91.54 ? 424 SER B N 424 SER B N 1 ATOM 4626 C CA . SER B 2 424 ? -25.617 3.338 2.276 1.00 91.54 ? 424 SER B CA 424 SER B CA 1 ATOM 4627 C C . SER B 2 424 ? -26.309 3.777 0.990 1.00 91.54 ? 424 SER B C 424 SER B C 1 ATOM 4628 O O . SER B 2 424 ? -26.144 3.147 -0.057 1.00 91.54 ? 424 SER B O 424 SER B O 1 ATOM 4629 C CB . SER B 2 424 ? -26.603 2.573 3.160 1.00 91.54 ? 424 SER B CB 424 SER B CB 1 ATOM 4630 O OG . SER B 2 424 ? -27.159 1.473 2.458 1.00 91.54 ? 424 SER B OG 424 SER B OG 1 ATOM 4631 N N . GLU B 2 425 ? -27.022 4.893 1.072 1.00 92.90 ? 425 GLU B N 425 GLU B N 1 ATOM 4632 C CA . GLU B 2 425 ? -27.694 5.437 -0.104 1.00 92.90 ? 425 GLU B CA 425 GLU B CA 1 ATOM 4633 C C . GLU B 2 425 ? -26.692 6.048 -1.079 1.00 92.90 ? 425 GLU B C 425 GLU B C 1 ATOM 4634 O O . GLU B 2 425 ? -26.801 5.854 -2.292 1.00 92.90 ? 425 GLU B O 425 GLU B O 1 ATOM 4635 C CB . GLU B 2 425 ? -28.734 6.484 0.307 1.00 92.90 ? 425 GLU B CB 425 GLU B CB 1 ATOM 4636 C CG . GLU B 2 425 ? -29.620 6.952 -0.838 1.00 92.90 ? 425 GLU B CG 425 GLU B CG 1 ATOM 4637 C CD . GLU B 2 425 ? -30.674 7.959 -0.407 1.00 92.90 ? 425 GLU B CD 425 GLU B CD 1 ATOM 4638 O OE1 . GLU B 2 425 ? -31.532 8.333 -1.239 1.00 92.90 ? 425 GLU B OE1 425 GLU B OE1 1 ATOM 4639 O OE2 . GLU B 2 425 ? -30.641 8.379 0.771 1.00 92.90 ? 425 GLU B OE2 425 GLU B OE2 1 ATOM 4640 N N . ILE B 2 426 ? -25.727 6.718 -0.526 1.00 92.32 ? 426 ILE B N 426 ILE B N 1 ATOM 4641 C CA . ILE B 2 426 ? -24.712 7.382 -1.337 1.00 92.32 ? 426 ILE B CA 426 ILE B CA 1 ATOM 4642 C C . ILE B 2 426 ? -23.893 6.339 -2.094 1.00 92.32 ? 426 ILE B C 426 ILE B C 1 ATOM 4643 O O . ILE B 2 426 ? -23.633 6.493 -3.290 1.00 92.32 ? 426 ILE B O 426 ILE B O 1 ATOM 4644 C CB . ILE B 2 426 ? -23.787 8.266 -0.472 1.00 92.32 ? 426 ILE B CB 426 ILE B CB 1 ATOM 4645 C CG1 . ILE B 2 426 ? -24.564 9.461 0.092 1.00 92.32 ? 426 ILE B CG1 426 ILE B CG1 1 ATOM 4646 C CG2 . ILE B 2 426 ? -22.574 8.734 -1.283 1.00 92.32 ? 426 ILE B CG2 426 ILE B CG2 1 ATOM 4647 C CD1 . ILE B 2 426 ? -23.780 10.288 1.102 1.00 92.32 ? 426 ILE B CD1 426 ILE B CD1 1 ATOM 4648 N N . SER B 2 427 ? -23.499 5.293 -1.403 1.00 91.11 ? 427 SER B N 427 SER B N 1 ATOM 4649 C CA . SER B 2 427 ? -22.711 4.232 -2.021 1.00 91.11 ? 427 SER B CA 427 SER B CA 1 ATOM 4650 C C . SER B 2 427 ? -23.539 3.443 -3.030 1.00 91.11 ? 427 SER B C 427 SER B C 1 ATOM 4651 O O . SER B 2 427 ? -23.030 3.041 -4.078 1.00 91.11 ? 427 SER B O 427 SER B O 1 ATOM 4652 C CB . SER B 2 427 ? -22.155 3.286 -0.954 1.00 91.11 ? 427 SER B CB 427 SER B CB 1 ATOM 4653 O OG . SER B 2 427 ? -23.208 2.657 -0.243 1.00 91.11 ? 427 SER B OG 427 SER B OG 1 ATOM 4654 N N . ASN B 2 428 ? -24.814 3.184 -2.790 1.00 89.68 ? 428 ASN B N 428 ASN B N 1 ATOM 4655 C CA . ASN B 2 428 ? -25.707 2.455 -3.684 1.00 89.68 ? 428 ASN B CA 428 ASN B CA 1 ATOM 4656 C C . ASN B 2 428 ? -25.945 3.218 -4.984 1.00 89.68 ? 428 ASN B C 428 ASN B C 1 ATOM 4657 O O . ASN B 2 428 ? -26.184 2.613 -6.030 1.00 89.68 ? 428 ASN B O 428 ASN B O 1 ATOM 4658 C CB . ASN B 2 428 ? -27.039 2.160 -2.990 1.00 89.68 ? 428 ASN B CB 428 ASN B CB 1 ATOM 4659 C CG . ASN B 2 428 ? -26.923 1.069 -1.945 1.00 89.68 ? 428 ASN B CG 428 ASN B CG 1 ATOM 4660 O OD1 . ASN B 2 428 ? -25.966 0.290 -1.945 1.00 89.68 ? 428 ASN B OD1 428 ASN B OD1 1 ATOM 4661 N ND2 . ASN B 2 428 ? -27.897 1.004 -1.045 1.00 89.68 ? 428 ASN B ND2 428 ASN B ND2 1 ATOM 4662 N N . ASN B 2 429 ? -25.835 4.510 -4.860 1.00 89.91 ? 429 ASN B N 429 ASN B N 1 ATOM 4663 C CA . ASN B 2 429 ? -26.018 5.341 -6.045 1.00 89.91 ? 429 ASN B CA 429 ASN B CA 1 ATOM 4664 C C . ASN B 2 429 ? -24.685 5.663 -6.715 1.00 89.91 ? 429 ASN B C 429 ASN B C 1 ATOM 4665 O O . ASN B 2 429 ? -24.611 6.554 -7.563 1.00 89.91 ? 429 ASN B O 429 ASN B O 1 ATOM 4666 C CB . ASN B 2 429 ? -26.759 6.631 -5.688 1.00 89.91 ? 429 ASN B CB 429 ASN B CB 1 ATOM 4667 C CG . ASN B 2 429 ? -28.218 6.393 -5.353 1.00 89.91 ? 429 ASN B CG 429 ASN B CG 1 ATOM 4668 O OD1 . ASN B 2 429 ? -28.894 5.590 -6.002 1.00 89.91 ? 429 ASN B OD1 429 ASN B OD1 1 ATOM 4669 N ND2 . ASN B 2 429 ? -28.714 7.088 -4.336 1.00 89.91 ? 429 ASN B ND2 429 ASN B ND2 1 ATOM 4670 N N . TYR B 2 430 ? -23.542 5.055 -6.204 1.00 87.27 ? 430 TYR B N 430 TYR B N 1 ATOM 4671 C CA . TYR B 2 430 ? -22.211 5.111 -6.797 1.00 87.27 ? 430 TYR B CA 430 TYR B CA 1 ATOM 4672 C C . TYR B 2 430 ? -21.646 6.525 -6.738 1.00 87.27 ? 430 TYR B C 430 TYR B C 1 ATOM 4673 O O . TYR B 2 430 ? -20.942 6.958 -7.653 1.00 87.27 ? 430 TYR B O 430 TYR B O 1 ATOM 4674 C CB . TYR B 2 430 ? -22.247 4.624 -8.248 1.00 87.27 ? 430 TYR B CB 430 TYR B CB 1 ATOM 4675 C CG . TYR B 2 430 ? -22.662 3.180 -8.394 1.00 87.27 ? 430 TYR B CG 430 TYR B CG 1 ATOM 4676 C CD1 . TYR B 2 430 ? -21.761 2.147 -8.145 1.00 87.27 ? 430 TYR B CD1 430 TYR B CD1 1 ATOM 4677 C CD2 . TYR B 2 430 ? -23.956 2.846 -8.781 1.00 87.27 ? 430 TYR B CD2 430 TYR B CD2 1 ATOM 4678 C CE1 . TYR B 2 430 ? -22.139 0.815 -8.280 1.00 87.27 ? 430 TYR B CE1 430 TYR B CE1 1 ATOM 4679 C CE2 . TYR B 2 430 ? -24.345 1.517 -8.918 1.00 87.27 ? 430 TYR B CE2 430 TYR B CE2 1 ATOM 4680 C CZ . TYR B 2 430 ? -23.431 0.511 -8.666 1.00 87.27 ? 430 TYR B CZ 430 TYR B CZ 1 ATOM 4681 O OH . TYR B 2 430 ? -23.811 -0.806 -8.801 1.00 87.27 ? 430 TYR B OH 430 TYR B OH 1 ATOM 4682 N N . LEU B 2 431 ? -22.239 7.347 -5.774 1.00 89.54 ? 431 LEU B N 431 LEU B N 1 ATOM 4683 C CA . LEU B 2 431 ? -21.669 8.671 -5.553 1.00 89.54 ? 431 LEU B CA 431 LEU B CA 1 ATOM 4684 C C . LEU B 2 431 ? -20.326 8.571 -4.837 1.00 89.54 ? 431 LEU B C 431 LEU B C 1 ATOM 4685 O O . LEU B 2 431 ? -19.470 9.446 -4.989 1.00 89.54 ? 431 LEU B O 431 LEU B O 1 ATOM 4686 C CB . LEU B 2 431 ? -22.631 9.540 -4.739 1.00 89.54 ? 431 LEU B CB 431 LEU B CB 1 ATOM 4687 C CG . LEU B 2 431 ? -23.994 9.821 -5.374 1.00 89.54 ? 431 LEU B CG 431 LEU B CG 1 ATOM 4688 C CD1 . LEU B 2 431 ? -24.894 10.562 -4.392 1.00 89.54 ? 431 LEU B CD1 431 LEU B CD1 1 ATOM 4689 C CD2 . LEU B 2 431 ? -23.829 10.619 -6.663 1.00 89.54 ? 431 LEU B CD2 431 LEU B CD2 1 ATOM 4690 N N . CYS B 2 432 ? -20.239 7.602 -4.048 1.00 88.82 ? 432 CYS B N 432 CYS B N 1 ATOM 4691 C CA . CYS B 2 432 ? -18.993 7.257 -3.372 1.00 88.82 ? 432 CYS B CA 432 CYS B CA 1 ATOM 4692 C C . CYS B 2 432 ? -18.614 5.804 -3.634 1.00 88.82 ? 432 CYS B C 432 CYS B C 1 ATOM 4693 O O . CYS B 2 432 ? -19.487 4.942 -3.752 1.00 88.82 ? 432 CYS B O 432 CYS B O 1 ATOM 4694 C CB . CYS B 2 432 ? -19.115 7.498 -1.867 1.00 88.82 ? 432 CYS B CB 432 CYS B CB 1 ATOM 4695 S SG . CYS B 2 432 ? -19.330 9.235 -1.424 1.00 88.82 ? 432 CYS B SG 432 CYS B SG 1 ATOM 4696 N N . VAL B 2 433 ? -17.334 5.599 -3.768 1.00 87.15 ? 433 VAL B N 433 VAL B N 1 ATOM 4697 C CA . VAL B 2 433 ? -16.809 4.253 -3.975 1.00 87.15 ? 433 VAL B CA 433 VAL B CA 1 ATOM 4698 C C . VAL B 2 433 ? -16.069 3.788 -2.723 1.00 87.15 ? 433 VAL B C 433 VAL B C 1 ATOM 4699 O O . VAL B 2 433 ? -15.274 4.537 -2.150 1.00 87.15 ? 433 VAL B O 433 VAL B O 1 ATOM 4700 C CB . VAL B 2 433 ? -15.872 4.192 -5.202 1.00 87.15 ? 433 VAL B CB 433 VAL B CB 1 ATOM 4701 C CG1 . VAL B 2 433 ? -15.318 2.781 -5.389 1.00 87.15 ? 433 VAL B CG1 433 VAL B CG1 1 ATOM 4702 C CG2 . VAL B 2 433 ? -16.608 4.652 -6.459 1.00 87.15 ? 433 VAL B CG2 433 VAL B CG2 1 ATOM 4703 N N . GLU B 2 434 ? -16.396 2.525 -2.350 1.00 88.17 ? 434 GLU B N 434 GLU B N 1 ATOM 4704 C CA . GLU B 2 434 ? -15.750 1.956 -1.170 1.00 88.17 ? 434 GLU B CA 434 GLU B CA 1 ATOM 4705 C C . GLU B 2 434 ? -14.400 1.339 -1.523 1.00 88.17 ? 434 GLU B C 434 GLU B C 1 ATOM 4706 O O . GLU B 2 434 ? -14.272 0.653 -2.539 1.00 88.17 ? 434 GLU B O 434 GLU B O 1 ATOM 4707 C CB . GLU B 2 434 ? -16.653 0.906 -0.517 1.00 88.17 ? 434 GLU B CB 434 GLU B CB 1 ATOM 4708 C CG . GLU B 2 434 ? -18.008 1.446 -0.081 1.00 88.17 ? 434 GLU B CG 434 GLU B CG 1 ATOM 4709 C CD . GLU B 2 434 ? -18.953 0.364 0.416 1.00 88.17 ? 434 GLU B CD 434 GLU B CD 1 ATOM 4710 O OE1 . GLU B 2 434 ? -20.092 0.691 0.821 1.00 88.17 ? 434 GLU B OE1 434 GLU B OE1 1 ATOM 4711 O OE2 . GLU B 2 434 ? -18.551 -0.821 0.402 1.00 88.17 ? 434 GLU B OE2 434 GLU B OE2 1 ATOM 4712 N N . SER B 2 435 ? -13.429 1.677 -0.681 1.00 88.70 ? 435 SER B N 435 SER B N 1 ATOM 4713 C CA . SER B 2 435 ? -12.151 0.983 -0.799 1.00 88.70 ? 435 SER B CA 435 SER B CA 1 ATOM 4714 C C . SER B 2 435 ? -12.234 -0.429 -0.229 1.00 88.70 ? 435 SER B C 435 SER B C 1 ATOM 4715 O O . SER B 2 435 ? -12.447 -0.607 0.972 1.00 88.70 ? 435 SER B O 435 SER B O 1 ATOM 4716 C CB . SER B 2 435 ? -11.048 1.766 -0.086 1.00 88.70 ? 435 SER B CB 435 SER B CB 1 ATOM 4717 O OG . SER B 2 435 ? -9.796 1.120 -0.235 1.00 88.70 ? 435 SER B OG 435 SER B OG 1 ATOM 4718 N N . PRO B 2 436 ? -12.104 -1.424 -1.135 1.00 89.27 ? 436 PRO B N 436 PRO B N 1 ATOM 4719 C CA . PRO B 2 436 ? -12.301 -2.807 -0.694 1.00 89.27 ? 436 PRO B CA 436 PRO B CA 1 ATOM 4720 C C . PRO B 2 436 ? -11.176 -3.303 0.212 1.00 89.27 ? 436 PRO B C 436 PRO B C 1 ATOM 4721 O O . PRO B 2 436 ? -10.035 -2.852 0.089 1.00 89.27 ? 436 PRO B O 436 PRO B O 1 ATOM 4722 C CB . PRO B 2 436 ? -12.332 -3.595 -2.006 1.00 89.27 ? 436 PRO B CB 436 PRO B CB 1 ATOM 4723 C CG . PRO B 2 436 ? -11.480 -2.805 -2.946 1.00 89.27 ? 436 PRO B CG 436 PRO B CG 1 ATOM 4724 C CD . PRO B 2 436 ? -11.660 -1.345 -2.642 1.00 89.27 ? 436 PRO B CD 436 PRO B CD 1 ATOM 4725 N N . ILE B 2 437 ? -11.593 -4.228 1.180 1.00 92.39 ? 437 ILE B N 437 ILE B N 1 ATOM 4726 C CA . ILE B 2 437 ? -10.623 -4.953 1.995 1.00 92.39 ? 437 ILE B CA 437 ILE B CA 1 ATOM 4727 C C . ILE B 2 437 ? -10.131 -6.184 1.238 1.00 92.39 ? 437 ILE B C 437 ILE B C 1 ATOM 4728 O O . ILE B 2 437 ? -10.934 -6.984 0.752 1.00 92.39 ? 437 ILE B O 437 ILE B O 1 ATOM 4729 C CB . ILE B 2 437 ? -11.225 -5.366 3.357 1.00 92.39 ? 437 ILE B CB 437 ILE B CB 1 ATOM 4730 C CG1 . ILE B 2 437 ? -11.756 -4.135 4.101 1.00 92.39 ? 437 ILE B CG1 437 ILE B CG1 1 ATOM 4731 C CG2 . ILE B 2 437 ? -10.189 -6.112 4.201 1.00 92.39 ? 437 ILE B CG2 437 ILE B CG2 1 ATOM 4732 C CD1 . ILE B 2 437 ? -12.624 -4.468 5.307 1.00 92.39 ? 437 ILE B CD1 437 ILE B CD1 1 ATOM 4733 N N . GLN B 2 438 ? -8.795 -6.283 1.118 1.00 93.05 ? 438 GLN B N 438 GLN B N 1 ATOM 4734 C CA . GLN B 2 438 ? -8.236 -7.371 0.323 1.00 93.05 ? 438 GLN B CA 438 GLN B CA 1 ATOM 4735 C C . GLN B 2 438 ? -7.375 -8.294 1.181 1.00 93.05 ? 438 GLN B C 438 GLN B C 1 ATOM 4736 O O . GLN B 2 438 ? -6.600 -7.827 2.018 1.00 93.05 ? 438 GLN B O 438 GLN B O 1 ATOM 4737 C CB . GLN B 2 438 ? -7.413 -6.819 -0.842 1.00 93.05 ? 438 GLN B CB 438 GLN B CB 1 ATOM 4738 C CG . GLN B 2 438 ? -8.226 -5.999 -1.835 1.00 93.05 ? 438 GLN B CG 438 GLN B CG 1 ATOM 4739 C CD . GLN B 2 438 ? -7.373 -5.393 -2.933 1.00 93.05 ? 438 GLN B CD 438 GLN B CD 1 ATOM 4740 O OE1 . GLN B 2 438 ? -6.199 -5.073 -2.720 1.00 93.05 ? 438 GLN B OE1 438 GLN B OE1 1 ATOM 4741 N NE2 . GLN B 2 438 ? -7.957 -5.229 -4.115 1.00 93.05 ? 438 GLN B NE2 438 GLN B NE2 1 ATOM 4742 N N . ILE B 2 439 ? -7.621 -9.584 0.950 1.00 94.25 ? 439 ILE B N 439 ILE B N 1 ATOM 4743 C CA . ILE B 2 439 ? -6.861 -10.613 1.652 1.00 94.25 ? 439 ILE B CA 439 ILE B CA 1 ATOM 4744 C C . ILE B 2 439 ? -5.993 -11.381 0.658 1.00 94.25 ? 439 ILE B C 439 ILE B C 1 ATOM 4745 O O . ILE B 2 439 ? -6.458 -11.758 -0.421 1.00 94.25 ? 439 ILE B O 439 ILE B O 1 ATOM 4746 C CB . ILE B 2 439 ? -7.793 -11.584 2.411 1.00 94.25 ? 439 ILE B CB 439 ILE B CB 1 ATOM 4747 C CG1 . ILE B 2 439 ? -8.652 -10.817 3.423 1.00 94.25 ? 439 ILE B CG1 439 ILE B CG1 1 ATOM 4748 C CG2 . ILE B 2 439 ? -6.980 -12.682 3.104 1.00 94.25 ? 439 ILE B CG2 439 ILE B CG2 1 ATOM 4749 C CD1 . ILE B 2 439 ? -9.764 -11.649 4.047 1.00 94.25 ? 439 ILE B CD1 439 ILE B CD1 1 ATOM 4750 N N . ALA B 2 440 ? -4.757 -11.577 1.074 1.00 95.01 ? 440 ALA B N 440 ALA B N 1 ATOM 4751 C CA . ALA B 2 440 ? -3.832 -12.319 0.220 1.00 95.01 ? 440 ALA B CA 440 ALA B CA 1 ATOM 4752 C C . ALA B 2 440 ? -4.066 -13.822 0.337 1.00 95.01 ? 440 ALA B C 440 ALA B C 1 ATOM 4753 O O . ALA B 2 440 ? -4.054 -14.375 1.439 1.00 95.01 ? 440 ALA B O 440 ALA B O 1 ATOM 4754 C CB . ALA B 2 440 ? -2.388 -11.979 0.578 1.00 95.01 ? 440 ALA B CB 440 ALA B CB 1 ATOM 4755 N N . ARG B 2 441 ? -4.291 -14.468 -0.852 1.00 94.07 ? 441 ARG B N 441 ARG B N 1 ATOM 4756 C CA . ARG B 2 441 ? -4.539 -15.905 -0.904 1.00 94.07 ? 441 ARG B CA 441 ARG B CA 1 ATOM 4757 C C . ARG B 2 441 ? -3.601 -16.586 -1.894 1.00 94.07 ? 441 ARG B C 441 ARG B C 1 ATOM 4758 O O . ARG B 2 441 ? -3.146 -15.964 -2.856 1.00 94.07 ? 441 ARG B O 441 ARG B O 1 ATOM 4759 C CB . ARG B 2 441 ? -5.994 -16.187 -1.282 1.00 94.07 ? 441 ARG B CB 441 ARG B CB 1 ATOM 4760 C CG . ARG B 2 441 ? -6.999 -15.768 -0.220 1.00 94.07 ? 441 ARG B CG 441 ARG B CG 1 ATOM 4761 C CD . ARG B 2 441 ? -7.140 -16.823 0.869 1.00 94.07 ? 441 ARG B CD 441 ARG B CD 1 ATOM 4762 N NE . ARG B 2 441 ? -8.275 -16.544 1.745 1.00 94.07 ? 441 ARG B NE 441 ARG B NE 1 ATOM 4763 C CZ . ARG B 2 441 ? -8.701 -17.350 2.714 1.00 94.07 ? 441 ARG B CZ 441 ARG B CZ 1 ATOM 4764 N NH1 . ARG B 2 441 ? -8.091 -18.506 2.951 1.00 94.07 ? 441 ARG B NH1 441 ARG B NH1 1 ATOM 4765 N NH2 . ARG B 2 441 ? -9.744 -16.998 3.451 1.00 94.07 ? 441 ARG B NH2 441 ARG B NH2 1 ATOM 4766 N N . TRP B 2 442 ? -3.305 -17.780 -1.535 1.00 94.66 ? 442 TRP B N 442 TRP B N 1 ATOM 4767 C CA . TRP B 2 442 ? -2.525 -18.634 -2.424 1.00 94.66 ? 442 TRP B CA 442 TRP B CA 1 ATOM 4768 C C . TRP B 2 442 ? -3.401 -19.714 -3.049 1.00 94.66 ? 442 TRP B C 442 TRP B C 1 ATOM 4769 O O . TRP B 2 442 ? -4.155 -20.393 -2.348 1.00 94.66 ? 442 TRP B O 442 TRP B O 1 ATOM 4770 C CB . TRP B 2 442 ? -1.360 -19.278 -1.667 1.00 94.66 ? 442 TRP B CB 442 TRP B CB 1 ATOM 4771 C CG . TRP B 2 442 ? -0.522 -20.196 -2.505 1.00 94.66 ? 442 TRP B CG 442 TRP B CG 1 ATOM 4772 C CD1 . TRP B 2 442 ? 0.542 -19.852 -3.291 1.00 94.66 ? 442 TRP B CD1 442 TRP B CD1 1 ATOM 4773 C CD2 . TRP B 2 442 ? -0.683 -21.611 -2.643 1.00 94.66 ? 442 TRP B CD2 442 TRP B CD2 1 ATOM 4774 N NE1 . TRP B 2 442 ? 1.054 -20.969 -3.910 1.00 94.66 ? 442 TRP B NE1 442 TRP B NE1 1 ATOM 4775 C CE2 . TRP B 2 442 ? 0.321 -22.061 -3.530 1.00 94.66 ? 442 TRP B CE2 442 TRP B CE2 1 ATOM 4776 C CE3 . TRP B 2 442 ? -1.578 -22.543 -2.103 1.00 94.66 ? 442 TRP B CE3 442 TRP B CE3 1 ATOM 4777 C CZ2 . TRP B 2 442 ? 0.453 -23.405 -3.888 1.00 94.66 ? 442 TRP B CZ2 442 TRP B CZ2 1 ATOM 4778 C CZ3 . TRP B 2 442 ? -1.445 -23.880 -2.460 1.00 94.66 ? 442 TRP B CZ3 442 TRP B CZ3 1 ATOM 4779 C CH2 . TRP B 2 442 ? -0.436 -24.296 -3.345 1.00 94.66 ? 442 TRP B CH2 442 TRP B CH2 1 ATOM 4780 N N . VAL B 2 443 ? -3.326 -19.865 -4.425 1.00 93.75 ? 443 VAL B N 443 VAL B N 1 ATOM 4781 C CA . VAL B 2 443 ? -4.075 -20.880 -5.159 1.00 93.75 ? 443 VAL B CA 443 VAL B CA 1 ATOM 4782 C C . VAL B 2 443 ? -3.120 -21.714 -6.010 1.00 93.75 ? 443 VAL B C 443 VAL B C 1 ATOM 4783 O O . VAL B 2 443 ? -2.345 -21.169 -6.800 1.00 93.75 ? 443 VAL B O 443 VAL B O 1 ATOM 4784 C CB . VAL B 2 443 ? -5.167 -20.246 -6.050 1.00 93.75 ? 443 VAL B CB 443 VAL B CB 1 ATOM 4785 C CG1 . VAL B 2 443 ? -5.974 -21.327 -6.767 1.00 93.75 ? 443 VAL B CG1 443 VAL B CG1 1 ATOM 4786 C CG2 . VAL B 2 443 ? -6.085 -19.355 -5.216 1.00 93.75 ? 443 VAL B CG2 443 VAL B CG2 1 ATOM 4787 N N . PRO B 2 444 ? -3.212 -22.961 -5.871 1.00 92.16 ? 444 PRO B N 444 PRO B N 1 ATOM 4788 C CA . PRO B 2 444 ? -2.344 -23.813 -6.688 1.00 92.16 ? 444 PRO B CA 444 PRO B CA 1 ATOM 4789 C C . PRO B 2 444 ? -2.665 -23.725 -8.178 1.00 92.16 ? 444 PRO B C 444 PRO B C 1 ATOM 4790 O O . PRO B 2 444 ? -3.837 -23.689 -8.560 1.00 92.16 ? 444 PRO B O 444 PRO B O 1 ATOM 4791 C CB . PRO B 2 444 ? -2.624 -25.219 -6.151 1.00 92.16 ? 444 PRO B CB 444 PRO B CB 1 ATOM 4792 C CG . PRO B 2 444 ? -3.247 -24.999 -4.810 1.00 92.16 ? 444 PRO B CG 444 PRO B CG 1 ATOM 4793 C CD . PRO B 2 444 ? -3.941 -23.667 -4.819 1.00 92.16 ? 444 PRO B CD 444 PRO B CD 1 ATOM 4794 N N . TRP B 2 445 ? -1.609 -23.772 -8.978 1.00 91.39 ? 445 TRP B N 445 TRP B N 1 ATOM 4795 C CA . TRP B 2 445 ? -1.756 -23.666 -10.425 1.00 91.39 ? 445 TRP B CA 445 TRP B CA 1 ATOM 4796 C C . TRP B 2 445 ? -2.500 -24.872 -10.987 1.00 91.39 ? 445 TRP B C 445 TRP B C 1 ATOM 4797 O O . TRP B 2 445 ? -3.193 -24.765 -12.001 1.00 91.39 ? 445 TRP B O 445 TRP B O 1 ATOM 4798 C CB . TRP B 2 445 ? -0.386 -23.537 -11.098 1.00 91.39 ? 445 TRP B CB 445 TRP B CB 1 ATOM 4799 C CG . TRP B 2 445 ? 0.174 -22.147 -11.078 1.00 91.39 ? 445 TRP B CG 445 TRP B CG 1 ATOM 4800 C CD1 . TRP B 2 445 ? 1.284 -21.714 -10.408 1.00 91.39 ? 445 TRP B CD1 445 TRP B CD1 1 ATOM 4801 C CD2 . TRP B 2 445 ? -0.355 -21.004 -11.758 1.00 91.39 ? 445 TRP B CD2 445 TRP B CD2 1 ATOM 4802 N NE1 . TRP B 2 445 ? 1.478 -20.371 -10.630 1.00 91.39 ? 445 TRP B NE1 445 TRP B NE1 1 ATOM 4803 C CE2 . TRP B 2 445 ? 0.487 -19.911 -11.455 1.00 91.39 ? 445 TRP B CE2 445 TRP B CE2 1 ATOM 4804 C CE3 . TRP B 2 445 ? -1.459 -20.798 -12.596 1.00 91.39 ? 445 TRP B CE3 445 TRP B CE3 1 ATOM 4805 C CZ2 . TRP B 2 445 ? 0.258 -18.629 -11.961 1.00 91.39 ? 445 TRP B CZ2 445 TRP B CZ2 1 ATOM 4806 C CZ3 . TRP B 2 445 ? -1.685 -19.522 -13.099 1.00 91.39 ? 445 TRP B CZ3 445 TRP B CZ3 1 ATOM 4807 C CH2 . TRP B 2 445 ? -0.829 -18.455 -12.778 1.00 91.39 ? 445 TRP B CH2 445 TRP B CH2 1 ATOM 4808 N N . ASP B 2 446 ? -2.402 -26.001 -10.374 1.00 90.04 ? 446 ASP B N 446 ASP B N 1 ATOM 4809 C CA . ASP B 2 446 ? -3.063 -27.225 -10.815 1.00 90.04 ? 446 ASP B CA 446 ASP B CA 1 ATOM 4810 C C . ASP B 2 446 ? -4.574 -27.027 -10.918 1.00 90.04 ? 446 ASP B C 446 ASP B C 1 ATOM 4811 O O . ASP B 2 446 ? -5.194 -27.438 -11.901 1.00 90.04 ? 446 ASP B O 446 ASP B O 1 ATOM 4812 C CB . ASP B 2 446 ? -2.748 -28.380 -9.862 1.00 90.04 ? 446 ASP B CB 446 ASP B CB 1 ATOM 4813 C CG . ASP B 2 446 ? -1.294 -28.816 -9.919 1.00 90.04 ? 446 ASP B CG 446 ASP B CG 1 ATOM 4814 O OD1 . ASP B 2 446 ? -0.604 -28.508 -10.914 1.00 90.04 ? 446 ASP B OD1 446 ASP B OD1 1 ATOM 4815 O OD2 . ASP B 2 446 ? -0.836 -29.476 -8.961 1.00 90.04 ? 446 ASP B OD2 446 ASP B OD2 1 ATOM 4816 N N . HIS B 2 447 ? -5.116 -26.392 -10.030 1.00 88.63 ? 447 HIS B N 447 HIS B N 1 ATOM 4817 C CA . HIS B 2 447 ? -6.556 -26.162 -9.996 1.00 88.63 ? 447 HIS B CA 447 HIS B CA 1 ATOM 4818 C C . HIS B 2 447 ? -6.971 -25.114 -11.023 1.00 88.63 ? 447 HIS B C 447 HIS B C 1 ATOM 4819 O O . HIS B 2 447 ? -8.039 -25.223 -11.630 1.00 88.63 ? 447 HIS B O 447 HIS B O 1 ATOM 4820 C CB . HIS B 2 447 ? -6.997 -25.729 -8.597 1.00 88.63 ? 447 HIS B CB 447 HIS B CB 1 ATOM 4821 C CG . HIS B 2 447 ? -6.989 -26.839 -7.594 1.00 88.63 ? 447 HIS B CG 447 HIS B CG 1 ATOM 4822 N ND1 . HIS B 2 447 ? -8.041 -27.717 -7.450 1.00 88.63 ? 447 HIS B ND1 447 HIS B ND1 1 ATOM 4823 C CD2 . HIS B 2 447 ? -6.055 -27.213 -6.689 1.00 88.63 ? 447 HIS B CD2 447 HIS B CD2 1 ATOM 4824 C CE1 . HIS B 2 447 ? -7.753 -28.586 -6.495 1.00 88.63 ? 447 HIS B CE1 447 HIS B CE1 1 ATOM 4825 N NE2 . HIS B 2 447 ? -6.553 -28.302 -6.017 1.00 88.63 ? 447 HIS B NE2 447 HIS B NE2 1 ATOM 4826 N N . ILE B 2 448 ? -6.135 -24.163 -11.169 1.00 90.05 ? 448 ILE B N 448 ILE B N 1 ATOM 4827 C CA . ILE B 2 448 ? -6.423 -23.105 -12.130 1.00 90.05 ? 448 ILE B CA 448 ILE B CA 1 ATOM 4828 C C . ILE B 2 448 ? -6.395 -23.673 -13.547 1.00 90.05 ? 448 ILE B C 448 ILE B C 1 ATOM 4829 O O . ILE B 2 448 ? -7.265 -23.363 -14.364 1.00 90.05 ? 448 ILE B O 448 ILE B O 1 ATOM 4830 C CB . ILE B 2 448 ? -5.419 -21.937 -12.002 1.00 90.05 ? 448 ILE B CB 448 ILE B CB 1 ATOM 4831 C CG1 . ILE B 2 448 ? -5.532 -21.286 -10.618 1.00 90.05 ? 448 ILE B CG1 448 ILE B CG1 1 ATOM 4832 C CG2 . ILE B 2 448 ? -5.645 -20.906 -13.112 1.00 90.05 ? 448 ILE B CG2 448 ILE B CG2 1 ATOM 4833 C CD1 . ILE B 2 448 ? -4.446 -20.259 -10.327 1.00 90.05 ? 448 ILE B CD1 448 ILE B CD1 1 ATOM 4834 N N . LEU B 2 449 ? -5.469 -24.509 -13.821 1.00 87.88 ? 449 LEU B N 449 LEU B N 1 ATOM 4835 C CA . LEU B 2 449 ? -5.282 -25.072 -15.154 1.00 87.88 ? 449 LEU B CA 449 LEU B CA 1 ATOM 4836 C C . LEU B 2 449 ? -6.401 -26.050 -15.494 1.00 87.88 ? 449 LEU B C 449 LEU B C 1 ATOM 4837 O O . LEU B 2 449 ? -6.755 -26.214 -16.663 1.00 87.88 ? 449 LEU B O 449 LEU B O 1 ATOM 4838 C CB . LEU B 2 449 ? -3.926 -25.775 -15.254 1.00 87.88 ? 449 LEU B CB 449 LEU B CB 1 ATOM 4839 C CG . LEU B 2 449 ? -2.690 -24.875 -15.210 1.00 87.88 ? 449 LEU B CG 449 LEU B CG 1 ATOM 4840 C CD1 . LEU B 2 449 ? -1.421 -25.719 -15.163 1.00 87.88 ? 449 LEU B CD1 449 LEU B CD1 1 ATOM 4841 C CD2 . LEU B 2 449 ? -2.670 -23.935 -16.411 1.00 87.88 ? 449 LEU B CD2 449 LEU B CD2 1 ATOM 4842 N N . LYS B 2 450 ? -7.000 -26.656 -14.491 1.00 87.92 ? 450 LYS B N 450 LYS B N 1 ATOM 4843 C CA . LYS B 2 450 ? -8.078 -27.619 -14.697 1.00 87.92 ? 450 LYS B CA 450 LYS B CA 1 ATOM 4844 C C . LYS B 2 450 ? -9.421 -26.913 -14.861 1.00 87.92 ? 450 LYS B C 450 LYS B C 1 ATOM 4845 O O . LYS B 2 450 ? -10.384 -27.506 -15.352 1.00 87.92 ? 450 LYS B O 450 LYS B O 1 ATOM 4846 C CB . LYS B 2 450 ? -8.145 -28.608 -13.533 1.00 87.92 ? 450 LYS B CB 450 LYS B CB 1 ATOM 4847 C CG . LYS B 2 450 ? -7.002 -29.612 -13.507 1.00 87.92 ? 450 LYS B CG 450 LYS B CG 1 ATOM 4848 C CD . LYS B 2 450 ? -7.114 -30.556 -12.317 1.00 87.92 ? 450 LYS B CD 450 LYS B CD 1 ATOM 4849 C CE . LYS B 2 450 ? -5.919 -31.497 -12.235 1.00 87.92 ? 450 LYS B CE 450 LYS B CE 1 ATOM 4850 N NZ . LYS B 2 450 ? -5.986 -32.373 -11.027 1.00 87.92 ? 450 LYS B NZ 450 LYS B NZ 1 ATOM 4851 N N . ALA B 2 451 ? -9.375 -25.631 -14.526 1.00 83.29 ? 451 ALA B N 451 ALA B N 1 ATOM 4852 C CA . ALA B 2 451 ? -10.618 -24.868 -14.602 1.00 83.29 ? 451 ALA B CA 451 ALA B CA 1 ATOM 4853 C C . ALA B 2 451 ? -10.925 -24.460 -16.041 1.00 83.29 ? 451 ALA B C 451 ALA B C 1 ATOM 4854 O O . ALA B 2 451 ? -10.015 -24.144 -16.810 1.00 83.29 ? 451 ALA B O 451 ALA B O 1 ATOM 4855 C CB . ALA B 2 451 ? -10.540 -23.633 -13.708 1.00 83.29 ? 451 ALA B CB 451 ALA B CB 1 ATOM 4856 N N . THR B 2 452 ? -12.098 -24.845 -16.495 1.00 70.54 ? 452 THR B N 452 THR B N 1 ATOM 4857 C CA . THR B 2 452 ? -12.557 -24.531 -17.843 1.00 70.54 ? 452 THR B CA 452 THR B CA 1 ATOM 4858 C C . THR B 2 452 ? -13.362 -23.235 -17.853 1.00 70.54 ? 452 THR B C 452 THR B C 1 ATOM 4859 O O . THR B 2 452 ? -14.238 -23.036 -17.009 1.00 70.54 ? 452 THR B O 452 THR B O 1 ATOM 4860 C CB . THR B 2 452 ? -13.412 -25.673 -18.423 1.00 70.54 ? 452 THR B CB 452 THR B CB 1 ATOM 4861 O OG1 . THR B 2 452 ? -14.507 -25.939 -17.538 1.00 70.54 ? 452 THR B OG1 452 THR B OG1 1 ATOM 4862 C CG2 . THR B 2 452 ? -12.588 -26.946 -18.591 1.00 70.54 ? 452 THR B CG2 452 THR B CG2 1 ATOM 4863 N N . ASN B 2 453 ? -12.786 -22.207 -18.678 1.00 73.43 ? 453 ASN B N 453 ASN B N 1 ATOM 4864 C CA . ASN B 2 453 ? -13.557 -20.986 -18.886 1.00 73.43 ? 453 ASN B CA 453 ASN B CA 1 ATOM 4865 C C . ASN B 2 453 ? -13.418 -20.472 -20.316 1.00 73.43 ? 453 ASN B C 453 ASN B C 1 ATOM 4866 O O . ASN B 2 453 ? -12.632 -19.559 -20.578 1.00 73.43 ? 453 ASN B O 453 ASN B O 1 ATOM 4867 C CB . ASN B 2 453 ? -13.132 -19.906 -17.890 1.00 73.43 ? 453 ASN B CB 453 ASN B CB 1 ATOM 4868 C CG . ASN B 2 453 ? -14.117 -18.756 -17.818 1.00 73.43 ? 453 ASN B CG 453 ASN B CG 1 ATOM 4869 O OD1 . ASN B 2 453 ? -15.162 -18.776 -18.474 1.00 73.43 ? 453 ASN B OD1 453 ASN B OD1 1 ATOM 4870 N ND2 . ASN B 2 453 ? -13.792 -17.745 -17.020 1.00 73.43 ? 453 ASN B ND2 453 ASN B ND2 1 ATOM 4871 N N . PRO B 2 454 ? -14.165 -21.071 -21.180 1.00 68.68 ? 454 PRO B N 454 PRO B N 1 ATOM 4872 C CA . PRO B 2 454 ? -14.050 -20.699 -22.593 1.00 68.68 ? 454 PRO B CA 454 PRO B CA 1 ATOM 4873 C C . PRO B 2 454 ? -14.457 -19.251 -22.857 1.00 68.68 ? 454 PRO B C 454 PRO B C 1 ATOM 4874 O O . PRO B 2 454 ? -13.873 -18.589 -23.719 1.00 68.68 ? 454 PRO B O 454 PRO B O 1 ATOM 4875 C CB . PRO B 2 454 ? -15.004 -21.671 -23.291 1.00 68.68 ? 454 PRO B CB 454 PRO B CB 1 ATOM 4876 C CG . PRO B 2 454 ? -15.866 -22.214 -22.197 1.00 68.68 ? 454 PRO B CG 454 PRO B CG 1 ATOM 4877 C CD . PRO B 2 454 ? -15.169 -21.990 -20.886 1.00 68.68 ? 454 PRO B CD 454 PRO B CD 1 ATOM 4878 N N . ASN B 2 455 ? -15.344 -18.610 -21.993 1.00 71.58 ? 455 ASN B N 455 ASN B N 1 ATOM 4879 C CA . ASN B 2 455 ? -15.852 -17.260 -22.212 1.00 71.58 ? 455 ASN B CA 455 ASN B CA 1 ATOM 4880 C C . ASN B 2 455 ? -15.220 -16.260 -21.247 1.00 71.58 ? 455 ASN B C 455 ASN B C 1 ATOM 4881 O O . ASN B 2 455 ? -15.755 -15.169 -21.039 1.00 71.58 ? 455 ASN B O 455 ASN B O 1 ATOM 4882 C CB . ASN B 2 455 ? -17.376 -17.232 -22.082 1.00 71.58 ? 455 ASN B CB 455 ASN B CB 1 ATOM 4883 C CG . ASN B 2 455 ? -18.069 -18.041 -23.161 1.00 71.58 ? 455 ASN B CG 455 ASN B CG 1 ATOM 4884 O OD1 . ASN B 2 455 ? -17.502 -18.290 -24.228 1.00 71.58 ? 455 ASN B OD1 455 ASN B OD1 1 ATOM 4885 N ND2 . ASN B 2 455 ? -19.301 -18.457 -22.891 1.00 71.58 ? 455 ASN B ND2 455 ASN B ND2 1 ATOM 4886 N N . GLY B 2 456 ? -14.188 -16.626 -20.597 1.00 67.61 ? 456 GLY B N 456 GLY B N 1 ATOM 4887 C CA . GLY B 2 456 ? -13.603 -15.815 -19.542 1.00 67.61 ? 456 GLY B CA 456 GLY B CA 1 ATOM 4888 C C . GLY B 2 456 ? -13.111 -14.465 -20.030 1.00 67.61 ? 456 GLY B C 456 GLY B C 1 ATOM 4889 O O . GLY B 2 456 ? -13.233 -13.462 -19.324 1.00 67.61 ? 456 GLY B O 456 GLY B O 1 ATOM 4890 N N . ASN B 2 457 ? -12.688 -14.415 -21.313 1.00 68.16 ? 457 ASN B N 457 ASN B N 1 ATOM 4891 C CA . ASN B 2 457 ? -12.175 -13.165 -21.863 1.00 68.16 ? 457 ASN B CA 457 ASN B CA 1 ATOM 4892 C C . ASN B 2 457 ? -13.287 -12.137 -22.051 1.00 68.16 ? 457 ASN B C 457 ASN B C 1 ATOM 4893 O O . ASN B 2 457 ? -13.027 -10.933 -22.084 1.00 68.16 ? 457 ASN B O 457 ASN B O 1 ATOM 4894 C CB . ASN B 2 457 ? -11.455 -13.417 -23.190 1.00 68.16 ? 457 ASN B CB 457 ASN B CB 1 ATOM 4895 C CG . ASN B 2 457 ? -10.148 -14.164 -23.012 1.00 68.16 ? 457 ASN B CG 457 ASN B CG 1 ATOM 4896 O OD1 . ASN B 2 457 ? -9.638 -14.290 -21.895 1.00 68.16 ? 457 ASN B OD1 457 ASN B OD1 1 ATOM 4897 N ND2 . ASN B 2 457 ? -9.596 -14.665 -24.111 1.00 68.16 ? 457 ASN B ND2 457 ASN B ND2 1 ATOM 4898 N N . LEU B 2 458 ? -14.576 -12.688 -22.062 1.00 68.99 ? 458 LEU B N 458 LEU B N 1 ATOM 4899 C CA . LEU B 2 458 ? -15.707 -11.796 -22.291 1.00 68.99 ? 458 LEU B CA 458 LEU B CA 1 ATOM 4900 C C . LEU B 2 458 ? -16.275 -11.288 -20.970 1.00 68.99 ? 458 LEU B C 458 LEU B C 1 ATOM 4901 O O . LEU B 2 458 ? -17.055 -10.332 -20.951 1.00 68.99 ? 458 LEU B O 458 LEU B O 1 ATOM 4902 C CB . LEU B 2 458 ? -16.801 -12.512 -23.088 1.00 68.99 ? 458 LEU B CB 458 LEU B CB 1 ATOM 4903 C CG . LEU B 2 458 ? -16.452 -12.894 -24.527 1.00 68.99 ? 458 LEU B CG 458 LEU B CG 1 ATOM 4904 C CD1 . LEU B 2 458 ? -17.353 -14.025 -25.009 1.00 68.99 ? 458 LEU B CD1 458 LEU B CD1 1 ATOM 4905 C CD2 . LEU B 2 458 ? -16.569 -11.682 -25.445 1.00 68.99 ? 458 LEU B CD2 458 LEU B CD2 1 ATOM 4906 N N . SER B 2 459 ? -15.902 -12.001 -19.906 1.00 62.95 ? 459 SER B N 459 SER B N 1 ATOM 4907 C CA . SER B 2 459 ? -16.520 -11.720 -18.614 1.00 62.95 ? 459 SER B CA 459 SER B CA 1 ATOM 4908 C C . SER B 2 459 ? -15.704 -10.705 -17.820 1.00 62.95 ? 459 SER B C 459 SER B C 1 ATOM 4909 O O . SER B 2 459 ? -14.518 -10.921 -17.559 1.00 62.95 ? 459 SER B O 459 SER B O 1 ATOM 4910 C CB . SER B 2 459 ? -16.676 -13.007 -17.803 1.00 62.95 ? 459 SER B CB 459 SER B CB 1 ATOM 4911 O OG . SER B 2 459 ? -15.419 -13.626 -17.595 1.00 62.95 ? 459 SER B OG 459 SER B OG 1 ATOM 4912 N N . TYR B 2 460 ? -15.869 -9.425 -18.192 1.00 67.26 ? 460 TYR B N 460 TYR B N 1 ATOM 4913 C CA . TYR B 2 460 ? -15.210 -8.365 -17.436 1.00 67.26 ? 460 TYR B CA 460 TYR B CA 1 ATOM 4914 C C . TYR B 2 460 ? -16.088 -7.891 -16.284 1.00 67.26 ? 460 TYR B C 460 TYR B C 1 ATOM 4915 O O . TYR B 2 460 ? -17.308 -7.783 -16.428 1.00 67.26 ? 460 TYR B O 460 TYR B O 1 ATOM 4916 C CB . TYR B 2 460 ? -14.868 -7.185 -18.351 1.00 67.26 ? 460 TYR B CB 460 TYR B CB 1 ATOM 4917 C CG . TYR B 2 460 ? -14.495 -5.927 -17.605 1.00 67.26 ? 460 TYR B CG 460 TYR B CG 1 ATOM 4918 C CD1 . TYR B 2 460 ? -15.439 -4.932 -17.361 1.00 67.26 ? 460 TYR B CD1 460 TYR B CD1 1 ATOM 4919 C CD2 . TYR B 2 460 ? -13.198 -5.730 -17.144 1.00 67.26 ? 460 TYR B CD2 460 TYR B CD2 1 ATOM 4920 C CE1 . TYR B 2 460 ? -15.099 -3.771 -16.675 1.00 67.26 ? 460 TYR B CE1 460 TYR B CE1 1 ATOM 4921 C CE2 . TYR B 2 460 ? -12.847 -4.572 -16.457 1.00 67.26 ? 460 TYR B CE2 460 TYR B CE2 1 ATOM 4922 C CZ . TYR B 2 460 ? -13.803 -3.600 -16.228 1.00 67.26 ? 460 TYR B CZ 460 TYR B CZ 1 ATOM 4923 O OH . TYR B 2 460 ? -13.461 -2.452 -15.549 1.00 67.26 ? 460 TYR B OH 460 TYR B OH 1 ATOM 4924 N N . ASP B 2 461 ? -15.523 -8.001 -15.069 1.00 64.15 ? 461 ASP B N 461 ASP B N 1 ATOM 4925 C CA . ASP B 2 461 ? -16.197 -7.443 -13.900 1.00 64.15 ? 461 ASP B CA 461 ASP B CA 1 ATOM 4926 C C . ASP B 2 461 ? -16.084 -5.921 -13.875 1.00 64.15 ? 461 ASP B C 461 ASP B C 1 ATOM 4927 O O . ASP B 2 461 ? -15.030 -5.377 -13.538 1.00 64.15 ? 461 ASP B O 461 ASP B O 1 ATOM 4928 C CB . ASP B 2 461 ? -15.619 -8.035 -12.613 1.00 64.15 ? 461 ASP B CB 461 ASP B CB 1 ATOM 4929 C CG . ASP B 2 461 ? -16.412 -7.652 -11.376 1.00 64.15 ? 461 ASP B CG 461 ASP B CG 1 ATOM 4930 O OD1 . ASP B 2 461 ? -17.441 -6.954 -11.502 1.00 64.15 ? 461 ASP B OD1 461 ASP B OD1 1 ATOM 4931 O OD2 . ASP B 2 461 ? -16.002 -8.051 -10.264 1.00 64.15 ? 461 ASP B OD2 461 ASP B OD2 1 ATOM 4932 N N . ALA B 2 462 ? -17.069 -5.230 -14.395 1.00 60.15 ? 462 ALA B N 462 ALA B N 1 ATOM 4933 C CA . ALA B 2 462 ? -17.122 -3.770 -14.426 1.00 60.15 ? 462 ALA B CA 462 ALA B CA 1 ATOM 4934 C C . ALA B 2 462 ? -17.150 -3.192 -13.015 1.00 60.15 ? 462 ALA B C 462 ALA B C 1 ATOM 4935 O O . ALA B 2 462 ? -16.854 -2.012 -12.814 1.00 60.15 ? 462 ALA B O 462 ALA B O 1 ATOM 4936 C CB . ALA B 2 462 ? -18.340 -3.299 -15.216 1.00 60.15 ? 462 ALA B CB 462 ALA B CB 1 ATOM 4937 N N . THR B 2 463 ? -17.449 -4.082 -12.038 1.00 59.71 ? 463 THR B N 463 THR B N 1 ATOM 4938 C CA . THR B 2 463 ? -17.671 -3.560 -10.694 1.00 59.71 ? 463 THR B CA 463 THR B CA 1 ATOM 4939 C C . THR B 2 463 ? -16.355 -3.462 -9.928 1.00 59.71 ? 463 THR B C 463 THR B C 1 ATOM 4940 O O . THR B 2 463 ? -16.297 -2.848 -8.860 1.00 59.71 ? 463 THR B O 463 THR B O 1 ATOM 4941 C CB . THR B 2 463 ? -18.661 -4.441 -9.910 1.00 59.71 ? 463 THR B CB 463 THR B CB 1 ATOM 4942 O OG1 . THR B 2 463 ? -18.161 -5.783 -9.859 1.00 59.71 ? 463 THR B OG1 463 THR B OG1 1 ATOM 4943 C CG2 . THR B 2 463 ? -20.035 -4.447 -10.572 1.00 59.71 ? 463 THR B CG2 463 THR B CG2 1 ATOM 4944 N N . SER B 2 464 ? -15.299 -4.104 -10.377 1.00 63.24 ? 464 SER B N 464 SER B N 1 ATOM 4945 C CA . SER B 2 464 ? -14.029 -4.022 -9.662 1.00 63.24 ? 464 SER B CA 464 SER B CA 1 ATOM 4946 C C . SER B 2 464 ? -13.445 -2.615 -9.734 1.00 63.24 ? 464 SER B C 464 SER B C 1 ATOM 4947 O O . SER B 2 464 ? -13.237 -2.079 -10.825 1.00 63.24 ? 464 SER B O 464 SER B O 1 ATOM 4948 C CB . SER B 2 464 ? -13.028 -5.029 -10.229 1.00 63.24 ? 464 SER B CB 464 SER B CB 1 ATOM 4949 O OG . SER B 2 464 ? -12.570 -4.619 -11.506 1.00 63.24 ? 464 SER B OG 464 SER B OG 1 ATOM 4950 N N . THR B 2 465 ? -13.670 -1.742 -8.835 1.00 55.19 ? 465 THR B N 465 THR B N 1 ATOM 4951 C CA . THR B 2 465 ? -13.579 -0.297 -8.651 1.00 55.19 ? 465 THR B CA 465 THR B CA 1 ATOM 4952 C C . THR B 2 465 ? -12.122 0.153 -8.617 1.00 55.19 ? 465 THR B C 465 THR B C 1 ATOM 4953 O O . THR B 2 465 ? -11.799 1.261 -9.052 1.00 55.19 ? 465 THR B O 465 THR B O 1 ATOM 4954 C CB . THR B 2 465 ? -14.286 0.146 -7.356 1.00 55.19 ? 465 THR B CB 465 THR B CB 1 ATOM 4955 O OG1 . THR B 2 465 ? -13.883 -0.712 -6.281 1.00 55.19 ? 465 THR B OG1 465 THR B OG1 1 ATOM 4956 C CG2 . THR B 2 465 ? -15.802 0.076 -7.506 1.00 55.19 ? 465 THR B CG2 465 THR B CG2 1 ATOM 4957 N N . LEU B 2 466 ? -11.141 -0.840 -9.011 1.00 62.90 ? 466 LEU B N 466 LEU B N 1 ATOM 4958 C CA . LEU B 2 466 ? -9.798 -0.284 -8.887 1.00 62.90 ? 466 LEU B CA 466 LEU B CA 1 ATOM 4959 C C . LEU B 2 466 ? -8.811 -1.049 -9.762 1.00 62.90 ? 466 LEU B C 466 LEU B C 1 ATOM 4960 O O . LEU B 2 466 ? -7.612 -1.076 -9.475 1.00 62.90 ? 466 LEU B O 466 LEU B O 1 ATOM 4961 C CB . LEU B 2 466 ? -9.337 -0.318 -7.428 1.00 62.90 ? 466 LEU B CB 466 LEU B CB 1 ATOM 4962 C CG . LEU B 2 466 ? -10.092 0.591 -6.457 1.00 62.90 ? 466 LEU B CG 466 LEU B CG 1 ATOM 4963 C CD1 . LEU B 2 466 ? -9.690 0.281 -5.019 1.00 62.90 ? 466 LEU B CD1 466 LEU B CD1 1 ATOM 4964 C CD2 . LEU B 2 466 ? -9.834 2.057 -6.785 1.00 62.90 ? 466 LEU B CD2 466 LEU B CD2 1 ATOM 4965 N N . THR B 2 467 ? -9.307 -1.473 -10.926 1.00 70.03 ? 467 THR B N 467 THR B N 1 ATOM 4966 C CA . THR B 2 467 ? -8.384 -2.192 -11.797 1.00 70.03 ? 467 THR B CA 467 THR B CA 1 ATOM 4967 C C . THR B 2 467 ? -7.766 -1.249 -12.825 1.00 70.03 ? 467 THR B C 467 THR B C 1 ATOM 4968 O O . THR B 2 467 ? -8.431 -0.335 -13.317 1.00 70.03 ? 467 THR B O 467 THR B O 1 ATOM 4969 C CB . THR B 2 467 ? -9.089 -3.354 -12.521 1.00 70.03 ? 467 THR B CB 467 THR B CB 1 ATOM 4970 O OG1 . THR B 2 467 ? -10.266 -2.860 -13.173 1.00 70.03 ? 467 THR B OG1 467 THR B OG1 1 ATOM 4971 C CG2 . THR B 2 467 ? -9.488 -4.452 -11.541 1.00 70.03 ? 467 THR B CG2 467 THR B CG2 1 ATOM 4972 N N . LEU B 2 468 ? -6.479 -1.367 -13.014 1.00 75.49 ? 468 LEU B N 468 LEU B N 1 ATOM 4973 C CA . LEU B 2 468 ? -5.755 -0.595 -14.018 1.00 75.49 ? 468 LEU B CA 468 LEU B CA 1 ATOM 4974 C C . LEU B 2 468 ? -6.121 -1.055 -15.425 1.00 75.49 ? 468 LEU B C 468 LEU B C 1 ATOM 4975 O O . LEU B 2 468 ? -6.472 -2.219 -15.631 1.00 75.49 ? 468 LEU B O 468 LEU B O 1 ATOM 4976 C CB . LEU B 2 468 ? -4.244 -0.721 -13.804 1.00 75.49 ? 468 LEU B CB 468 LEU B CB 1 ATOM 4977 C CG . LEU B 2 468 ? -3.681 -0.065 -12.542 1.00 75.49 ? 468 LEU B CG 468 LEU B CG 1 ATOM 4978 C CD1 . LEU B 2 468 ? -2.260 -0.551 -12.281 1.00 75.49 ? 468 LEU B CD1 468 LEU B CD1 1 ATOM 4979 C CD2 . LEU B 2 468 ? -3.717 1.455 -12.668 1.00 75.49 ? 468 LEU B CD2 468 LEU B CD2 1 ATOM 4980 N N . PRO B 2 469 ? -6.181 -0.071 -16.261 1.00 75.62 ? 469 PRO B N 469 PRO B N 1 ATOM 4981 C CA . PRO B 2 469 ? -6.479 -0.432 -17.649 1.00 75.62 ? 469 PRO B CA 469 PRO B CA 1 ATOM 4982 C C . PRO B 2 469 ? -5.521 -1.484 -18.204 1.00 75.62 ? 469 PRO B C 469 PRO B C 1 ATOM 4983 O O . PRO B 2 469 ? -4.318 -1.432 -17.935 1.00 75.62 ? 469 PRO B O 469 PRO B O 1 ATOM 4984 C CB . PRO B 2 469 ? -6.326 0.894 -18.399 1.00 75.62 ? 469 PRO B CB 469 PRO B CB 1 ATOM 4985 C CG . PRO B 2 469 ? -6.451 1.945 -17.344 1.00 75.62 ? 469 PRO B CG 469 PRO B CG 1 ATOM 4986 C CD . PRO B 2 469 ? -5.988 1.368 -16.038 1.00 75.62 ? 469 PRO B CD 469 PRO B CD 1 ATOM 4987 N N . GLY B 2 470 ? -6.005 -2.546 -18.835 1.00 77.37 ? 470 GLY B N 470 GLY B N 1 ATOM 4988 C CA . GLY B 2 470 ? -5.222 -3.621 -19.423 1.00 77.37 ? 470 GLY B CA 470 GLY B CA 1 ATOM 4989 C C . GLY B 2 470 ? -5.082 -4.825 -18.511 1.00 77.37 ? 470 GLY B C 470 GLY B C 1 ATOM 4990 O O . GLY B 2 470 ? -4.668 -5.900 -18.951 1.00 77.37 ? 470 GLY B O 470 GLY B O 1 ATOM 4991 N N . HIS B 2 471 ? -5.402 -4.649 -17.316 1.00 81.25 ? 471 HIS B N 471 HIS B N 1 ATOM 4992 C CA . HIS B 2 471 ? -5.256 -5.728 -16.345 1.00 81.25 ? 471 HIS B CA 471 HIS B CA 1 ATOM 4993 C C . HIS B 2 471 ? -6.599 -6.097 -15.726 1.00 81.25 ? 471 HIS B C 471 HIS B C 1 ATOM 4994 O O . HIS B 2 471 ? -6.668 -6.446 -14.545 1.00 81.25 ? 471 HIS B O 471 HIS B O 1 ATOM 4995 C CB . HIS B 2 471 ? -4.264 -5.333 -15.250 1.00 81.25 ? 471 HIS B CB 471 HIS B CB 1 ATOM 4996 C CG . HIS B 2 471 ? -2.875 -5.101 -15.755 1.00 81.25 ? 471 HIS B CG 471 HIS B CG 1 ATOM 4997 N ND1 . HIS B 2 471 ? -2.072 -6.120 -16.219 1.00 81.25 ? 471 HIS B ND1 471 HIS B ND1 1 ATOM 4998 C CD2 . HIS B 2 471 ? -2.149 -3.964 -15.869 1.00 81.25 ? 471 HIS B CD2 471 HIS B CD2 1 ATOM 4999 C CE1 . HIS B 2 471 ? -0.908 -5.618 -16.597 1.00 81.25 ? 471 HIS B CE1 471 HIS B CE1 1 ATOM 5000 N NE2 . HIS B 2 471 ? -0.929 -4.312 -16.396 1.00 81.25 ? 471 HIS B NE2 471 HIS B NE2 1 ATOM 5001 N N . GLU B 2 472 ? -7.678 -5.960 -16.505 1.00 80.56 ? 472 GLU B N 472 GLU B N 1 ATOM 5002 C CA . GLU B 2 472 ? -9.028 -6.236 -16.025 1.00 80.56 ? 472 GLU B CA 472 GLU B CA 1 ATOM 5003 C C . GLU B 2 472 ? -9.238 -7.730 -15.796 1.00 80.56 ? 472 GLU B C 472 GLU B C 1 ATOM 5004 O O . GLU B 2 472 ? -9.937 -8.128 -14.861 1.00 80.56 ? 472 GLU B O 472 GLU B O 1 ATOM 5005 C CB . GLU B 2 472 ? -10.069 -5.704 -17.014 1.00 80.56 ? 472 GLU B CB 472 GLU B CB 1 ATOM 5006 C CG . GLU B 2 472 ? -10.046 -4.191 -17.177 1.00 80.56 ? 472 GLU B CG 472 GLU B CG 1 ATOM 5007 C CD . GLU B 2 472 ? -10.974 -3.692 -18.273 1.00 80.56 ? 472 GLU B CD 472 GLU B CD 1 ATOM 5008 O OE1 . GLU B 2 472 ? -11.048 -2.461 -18.491 1.00 80.56 ? 472 GLU B OE1 472 GLU B OE1 1 ATOM 5009 O OE2 . GLU B 2 472 ? -11.633 -4.538 -18.918 1.00 80.56 ? 472 GLU B OE2 472 GLU B OE2 1 ATOM 5010 N N . LEU B 2 473 ? -8.602 -8.459 -16.723 1.00 84.93 ? 473 LEU B N 473 LEU B N 1 ATOM 5011 C CA . LEU B 2 473 ? -8.620 -9.907 -16.545 1.00 84.93 ? 473 LEU B CA 473 LEU B CA 1 ATOM 5012 C C . LEU B 2 473 ? -7.386 -10.375 -15.781 1.00 84.93 ? 473 LEU B C 473 LEU B C 1 ATOM 5013 O O . LEU B 2 473 ? -6.256 -10.164 -16.228 1.00 84.93 ? 473 LEU B O 473 LEU B O 1 ATOM 5014 C CB . LEU B 2 473 ? -8.694 -10.613 -17.901 1.00 84.93 ? 473 LEU B CB 473 LEU B CB 1 ATOM 5015 C CG . LEU B 2 473 ? -8.997 -12.112 -17.869 1.00 84.93 ? 473 LEU B CG 473 LEU B CG 1 ATOM 5016 C CD1 . LEU B 2 473 ? -10.402 -12.357 -17.331 1.00 84.93 ? 473 LEU B CD1 473 LEU B CD1 1 ATOM 5017 C CD2 . LEU B 2 473 ? -8.836 -12.720 -19.258 1.00 84.93 ? 473 LEU B CD2 473 LEU B CD2 1 ATOM 5018 N N . PRO B 2 474 ? -7.631 -11.047 -14.573 1.00 87.06 ? 474 PRO B N 474 PRO B N 1 ATOM 5019 C CA . PRO B 2 474 ? -6.491 -11.467 -13.756 1.00 87.06 ? 474 PRO B CA 474 PRO B CA 1 ATOM 5020 C C . PRO B 2 474 ? -5.515 -12.361 -14.519 1.00 87.06 ? 474 PRO B C 474 PRO B C 1 ATOM 5021 O O . PRO B 2 474 ? -4.299 -12.185 -14.413 1.00 87.06 ? 474 PRO B O 474 PRO B O 1 ATOM 5022 C CB . PRO B 2 474 ? -7.146 -12.233 -12.603 1.00 87.06 ? 474 PRO B CB 474 PRO B CB 1 ATOM 5023 C CG . PRO B 2 474 ? -8.535 -11.687 -12.522 1.00 87.06 ? 474 PRO B CG 474 PRO B CG 1 ATOM 5024 C CD . PRO B 2 474 ? -8.956 -11.249 -13.895 1.00 87.06 ? 474 PRO B CD 474 PRO B CD 1 ATOM 5025 N N . LEU B 2 475 ? -5.999 -13.366 -15.265 1.00 88.23 ? 475 LEU B N 475 LEU B N 1 ATOM 5026 C CA . LEU B 2 475 ? -5.173 -14.277 -16.050 1.00 88.23 ? 475 LEU B CA 475 LEU B CA 1 ATOM 5027 C C . LEU B 2 475 ? -5.610 -14.285 -17.511 1.00 88.23 ? 475 LEU B C 475 LEU B C 1 ATOM 5028 O O . LEU B 2 475 ? -6.352 -15.173 -17.936 1.00 88.23 ? 475 LEU B O 475 LEU B O 1 ATOM 5029 C CB . LEU B 2 475 ? -5.243 -15.694 -15.476 1.00 88.23 ? 475 LEU B CB 475 LEU B CB 1 ATOM 5030 C CG . LEU B 2 475 ? -4.785 -15.863 -14.026 1.00 88.23 ? 475 LEU B CG 475 LEU B CG 1 ATOM 5031 C CD1 . LEU B 2 475 ? -5.123 -17.262 -13.523 1.00 88.23 ? 475 LEU B CD1 475 LEU B CD1 1 ATOM 5032 C CD2 . LEU B 2 475 ? -3.290 -15.590 -13.903 1.00 88.23 ? 475 LEU B CD2 475 LEU B CD2 1 ATOM 5033 N N . PRO B 2 476 ? -5.187 -13.306 -18.282 1.00 83.90 ? 476 PRO B N 476 PRO B N 1 ATOM 5034 C CA . PRO B 2 476 ? -5.641 -13.100 -19.659 1.00 83.90 ? 476 PRO B CA 476 PRO B CA 1 ATOM 5035 C C . PRO B 2 476 ? -5.285 -14.266 -20.578 1.00 83.90 ? 476 PRO B C 476 PRO B C 1 ATOM 5036 O O . PRO B 2 476 ? -6.072 -14.627 -21.457 1.00 83.90 ? 476 PRO B O 476 PRO B O 1 ATOM 5037 C CB . PRO B 2 476 ? -4.909 -11.826 -20.086 1.00 83.90 ? 476 PRO B CB 476 PRO B CB 1 ATOM 5038 C CG . PRO B 2 476 ? -3.759 -11.710 -19.137 1.00 83.90 ? 476 PRO B CG 476 PRO B CG 1 ATOM 5039 C CD . PRO B 2 476 ? -4.148 -12.351 -17.836 1.00 83.90 ? 476 PRO B CD 476 PRO B CD 1 ATOM 5040 N N . LYS B 2 477 ? -4.075 -14.888 -20.401 1.00 84.17 ? 477 LYS B N 477 LYS B N 1 ATOM 5041 C CA . LYS B 2 477 ? -3.638 -15.968 -21.282 1.00 84.17 ? 477 LYS B CA 477 LYS B CA 1 ATOM 5042 C C . LYS B 2 477 ? -4.451 -17.236 -21.042 1.00 84.17 ? 477 LYS B C 477 LYS B C 1 ATOM 5043 O O . LYS B 2 477 ? -4.694 -18.010 -21.971 1.00 84.17 ? 477 LYS B O 477 LYS B O 1 ATOM 5044 C CB . LYS B 2 477 ? -2.149 -16.255 -21.082 1.00 84.17 ? 477 LYS B CB 477 LYS B CB 1 ATOM 5045 C CG . LYS B 2 477 ? -1.246 -15.063 -21.363 1.00 84.17 ? 477 LYS B CG 477 LYS B CG 1 ATOM 5046 C CD . LYS B 2 477 ? -1.286 -14.666 -22.833 1.00 84.17 ? 477 LYS B CD 477 LYS B CD 1 ATOM 5047 C CE . LYS B 2 477 ? -0.319 -13.528 -23.133 1.00 84.17 ? 477 LYS B CE 477 LYS B CE 1 ATOM 5048 N NZ . LYS B 2 477 ? -0.461 -13.036 -24.536 1.00 84.17 ? 477 LYS B NZ 477 LYS B NZ 1 ATOM 5049 N N . LEU B 2 478 ? -4.905 -17.416 -19.835 1.00 84.89 ? 478 LEU B N 478 LEU B N 1 ATOM 5050 C CA . LEU B 2 478 ? -5.732 -18.565 -19.482 1.00 84.89 ? 478 LEU B CA 478 LEU B CA 1 ATOM 5051 C C . LEU B 2 478 ? -7.214 -18.224 -19.596 1.00 84.89 ? 478 LEU B C 478 LEU B C 1 ATOM 5052 O O . LEU B 2 478 ? -8.064 -19.117 -19.579 1.00 84.89 ? 478 LEU B O 478 LEU B O 1 ATOM 5053 C CB . LEU B 2 478 ? -5.413 -19.040 -18.062 1.00 84.89 ? 478 LEU B CB 478 LEU B CB 1 ATOM 5054 C CG . LEU B 2 478 ? -4.058 -19.721 -17.863 1.00 84.89 ? 478 LEU B CG 478 LEU B CG 1 ATOM 5055 C CD1 . LEU B 2 478 ? -3.781 -19.925 -16.377 1.00 84.89 ? 478 LEU B CD1 478 LEU B CD1 1 ATOM 5056 C CD2 . LEU B 2 478 ? -4.013 -21.050 -18.608 1.00 84.89 ? 478 LEU B CD2 478 LEU B CD2 1 ATOM 5057 N N . GLY B 2 479 ? -7.589 -16.911 -19.781 1.00 80.90 ? 479 GLY B N 479 GLY B N 1 ATOM 5058 C CA . GLY B 2 479 ? -8.964 -16.453 -19.901 1.00 80.90 ? 479 GLY B CA 479 GLY B CA 1 ATOM 5059 C C . GLY B 2 479 ? -9.749 -16.575 -18.609 1.00 80.90 ? 479 GLY B C 479 GLY B C 1 ATOM 5060 O O . GLY B 2 479 ? -10.966 -16.768 -18.631 1.00 80.90 ? 479 GLY B O 479 GLY B O 1 ATOM 5061 N N . VAL B 2 480 ? -9.056 -16.571 -17.445 1.00 86.61 ? 480 VAL B N 480 VAL B N 1 ATOM 5062 C CA . VAL B 2 480 ? -9.712 -16.685 -16.147 1.00 86.61 ? 480 VAL B CA 480 VAL B CA 1 ATOM 5063 C C . VAL B 2 480 ? -10.150 -15.303 -15.666 1.00 86.61 ? 480 VAL B C 480 VAL B C 1 ATOM 5064 O O . VAL B 2 480 ? -9.325 -14.396 -15.530 1.00 86.61 ? 480 VAL B O 480 VAL B O 1 ATOM 5065 C CB . VAL B 2 480 ? -8.787 -17.345 -15.100 1.00 86.61 ? 480 VAL B CB 480 VAL B CB 1 ATOM 5066 C CG1 . VAL B 2 480 ? -9.465 -17.389 -13.732 1.00 86.61 ? 480 VAL B CG1 480 VAL B CG1 1 ATOM 5067 C CG2 . VAL B 2 480 ? -8.391 -18.750 -15.549 1.00 86.61 ? 480 VAL B CG2 480 VAL B CG2 1 ATOM 5068 N N . SER B 2 481 ? -11.473 -15.155 -15.470 1.00 86.13 ? 481 SER B N 481 SER B N 1 ATOM 5069 C CA . SER B 2 481 ? -12.043 -13.898 -14.994 1.00 86.13 ? 481 SER B CA 481 SER B CA 1 ATOM 5070 C C . SER B 2 481 ? -11.916 -13.772 -13.479 1.00 86.13 ? 481 SER B C 481 SER B C 1 ATOM 5071 O O . SER B 2 481 ? -11.556 -14.735 -12.799 1.00 86.13 ? 481 SER B O 481 SER B O 1 ATOM 5072 C CB . SER B 2 481 ? -13.512 -13.786 -15.402 1.00 86.13 ? 481 SER B CB 481 SER B CB 1 ATOM 5073 O OG . SER B 2 481 ? -14.290 -14.779 -14.756 1.00 86.13 ? 481 SER B OG 481 SER B OG 1 ATOM 5074 N N . ALA B 2 482 ? -12.090 -12.547 -12.907 1.00 85.89 ? 482 ALA B N 482 ALA B N 1 ATOM 5075 C CA . ALA B 2 482 ? -12.027 -12.271 -11.474 1.00 85.89 ? 482 ALA B CA 482 ALA B CA 1 ATOM 5076 C C . ALA B 2 482 ? -13.044 -13.112 -10.708 1.00 85.89 ? 482 ALA B C 482 ALA B C 1 ATOM 5077 O O . ALA B 2 482 ? -12.746 -13.626 -9.627 1.00 85.89 ? 482 ALA B O 482 ALA B O 1 ATOM 5078 C CB . ALA B 2 482 ? -12.261 -10.786 -11.208 1.00 85.89 ? 482 ALA B CB 482 ALA B CB 1 ATOM 5079 N N . ILE B 2 483 ? -14.254 -13.285 -11.332 1.00 85.83 ? 483 ILE B N 483 ILE B N 1 ATOM 5080 C CA . ILE B 2 483 ? -15.330 -14.044 -10.704 1.00 85.83 ? 483 ILE B CA 483 ILE B CA 1 ATOM 5081 C C . ILE B 2 483 ? -14.939 -15.517 -10.616 1.00 85.83 ? 483 ILE B C 483 ILE B C 1 ATOM 5082 O O . ILE B 2 483 ? -15.170 -16.167 -9.594 1.00 85.83 ? 483 ILE B O 483 ILE B O 1 ATOM 5083 C CB . ILE B 2 483 ? -16.658 -13.887 -11.477 1.00 85.83 ? 483 ILE B CB 483 ILE B CB 1 ATOM 5084 C CG1 . ILE B 2 483 ? -17.146 -12.435 -11.411 1.00 85.83 ? 483 ILE B CG1 483 ILE B CG1 1 ATOM 5085 C CG2 . ILE B 2 483 ? -17.719 -14.846 -10.928 1.00 85.83 ? 483 ILE B CG2 483 ILE B CG2 1 ATOM 5086 C CD1 . ILE B 2 483 ? -18.284 -12.120 -12.373 1.00 85.83 ? 483 ILE B CD1 483 ILE B CD1 1 ATOM 5087 N N . LYS B 2 484 ? -14.408 -15.978 -11.632 1.00 87.64 ? 484 LYS B N 484 LYS B N 1 ATOM 5088 C CA . LYS B 2 484 ? -13.977 -17.373 -11.649 1.00 87.64 ? 484 LYS B CA 484 LYS B CA 1 ATOM 5089 C C . LYS B 2 484 ? -12.844 -17.610 -10.654 1.00 87.64 ? 484 LYS B C 484 LYS B C 1 ATOM 5090 O O . LYS B 2 484 ? -12.805 -18.645 -9.985 1.00 87.64 ? 484 LYS B O 484 LYS B O 1 ATOM 5091 C CB . LYS B 2 484 ? -13.534 -17.782 -13.054 1.00 87.64 ? 484 LYS B CB 484 LYS B CB 1 ATOM 5092 C CG . LYS B 2 484 ? -13.169 -19.253 -13.185 1.00 87.64 ? 484 LYS B CG 484 LYS B CG 1 ATOM 5093 C CD . LYS B 2 484 ? -14.386 -20.150 -12.999 1.00 87.64 ? 484 LYS B CD 484 LYS B CD 1 ATOM 5094 C CE . LYS B 2 484 ? -14.039 -21.617 -13.214 1.00 87.64 ? 484 LYS B CE 484 LYS B CE 1 ATOM 5095 N NZ . LYS B 2 484 ? -15.222 -22.503 -12.998 1.00 87.64 ? 484 LYS B NZ 484 LYS B NZ 1 ATOM 5096 N N . LEU B 2 485 ? -11.890 -16.738 -10.699 1.00 88.53 ? 485 LEU B N 485 LEU B N 1 ATOM 5097 C CA . LEU B 2 485 ? -10.789 -16.850 -9.748 1.00 88.53 ? 485 LEU B CA 485 LEU B CA 1 ATOM 5098 C C . LEU B 2 485 ? -11.308 -16.847 -8.314 1.00 88.53 ? 485 LEU B C 485 LEU B C 1 ATOM 5099 O O . LEU B 2 485 ? -10.817 -17.600 -7.470 1.00 88.53 ? 485 LEU B O 485 LEU B O 1 ATOM 5100 C CB . LEU B 2 485 ? -9.792 -15.704 -9.945 1.00 88.53 ? 485 LEU B CB 485 LEU B CB 1 ATOM 5101 C CG . LEU B 2 485 ? -8.478 -15.809 -9.170 1.00 88.53 ? 485 LEU B CG 485 LEU B CG 1 ATOM 5102 C CD1 . LEU B 2 485 ? -7.715 -17.062 -9.588 1.00 88.53 ? 485 LEU B CD1 485 LEU B CD1 1 ATOM 5103 C CD2 . LEU B 2 485 ? -7.628 -14.562 -9.388 1.00 88.53 ? 485 LEU B CD2 485 LEU B CD2 1 ATOM 5104 N N . LYS B 2 486 ? -12.303 -16.012 -8.076 1.00 88.50 ? 486 LYS B N 486 LYS B N 1 ATOM 5105 C CA . LYS B 2 486 ? -12.955 -15.995 -6.769 1.00 88.50 ? 486 LYS B CA 486 LYS B CA 1 ATOM 5106 C C . LYS B 2 486 ? -13.594 -17.345 -6.457 1.00 88.50 ? 486 LYS B C 486 LYS B C 1 ATOM 5107 O O . LYS B 2 486 ? -13.474 -17.851 -5.339 1.00 88.50 ? 486 LYS B O 486 LYS B O 1 ATOM 5108 C CB . LYS B 2 486 ? -14.010 -14.889 -6.710 1.00 88.50 ? 486 LYS B CB 486 LYS B CB 1 ATOM 5109 C CG . LYS B 2 486 ? -14.640 -14.709 -5.336 1.00 88.50 ? 486 LYS B CG 486 LYS B CG 1 ATOM 5110 C CD . LYS B 2 486 ? -15.635 -13.555 -5.326 1.00 88.50 ? 486 LYS B CD 486 LYS B CD 1 ATOM 5111 C CE . LYS B 2 486 ? -16.304 -13.406 -3.966 1.00 88.50 ? 486 LYS B CE 486 LYS B CE 1 ATOM 5112 N NZ . LYS B 2 486 ? -17.285 -12.280 -3.952 1.00 88.50 ? 486 LYS B NZ 486 LYS B NZ 1 ATOM 5113 N N . SER B 2 487 ? -14.252 -17.896 -7.443 1.00 88.22 ? 487 SER B N 487 SER B N 1 ATOM 5114 C CA . SER B 2 487 ? -14.881 -19.204 -7.291 1.00 88.22 ? 487 SER B CA 487 SER B CA 1 ATOM 5115 C C . SER B 2 487 ? -13.843 -20.287 -7.012 1.00 88.22 ? 487 SER B C 487 SER B C 1 ATOM 5116 O O . SER B 2 487 ? -14.061 -21.161 -6.171 1.00 88.22 ? 487 SER B O 487 SER B O 1 ATOM 5117 C CB . SER B 2 487 ? -15.680 -19.563 -8.544 1.00 88.22 ? 487 SER B CB 487 SER B CB 1 ATOM 5118 O OG . SER B 2 487 ? -16.236 -20.862 -8.431 1.00 88.22 ? 487 SER B OG 487 SER B OG 1 ATOM 5119 N N . LEU B 2 488 ? -12.733 -20.241 -7.667 1.00 88.85 ? 488 LEU B N 488 LEU B N 1 ATOM 5120 C CA . LEU B 2 488 ? -11.666 -21.221 -7.498 1.00 88.85 ? 488 LEU B CA 488 LEU B CA 1 ATOM 5121 C C . LEU B 2 488 ? -11.058 -21.127 -6.103 1.00 88.85 ? 488 LEU B C 488 LEU B C 1 ATOM 5122 O O . LEU B 2 488 ? -10.742 -22.149 -5.488 1.00 88.85 ? 488 LEU B O 488 LEU B O 1 ATOM 5123 C CB . LEU B 2 488 ? -10.578 -21.017 -8.556 1.00 88.85 ? 488 LEU B CB 488 LEU B CB 1 ATOM 5124 C CG . LEU B 2 488 ? -10.914 -21.488 -9.972 1.00 88.85 ? 488 LEU B CG 488 LEU B CG 1 ATOM 5125 C CD1 . LEU B 2 488 ? -9.858 -20.998 -10.958 1.00 88.85 ? 488 LEU B CD1 488 LEU B CD1 1 ATOM 5126 C CD2 . LEU B 2 488 ? -11.029 -23.008 -10.017 1.00 88.85 ? 488 LEU B CD2 488 LEU B CD2 1 ATOM 5127 N N . MET B 2 489 ? -10.898 -19.922 -5.663 1.00 89.33 ? 489 MET B N 489 MET B N 1 ATOM 5128 C CA . MET B 2 489 ? -10.346 -19.708 -4.328 1.00 89.33 ? 489 MET B CA 489 MET B CA 1 ATOM 5129 C C . MET B 2 489 ? -11.270 -20.280 -3.258 1.00 89.33 ? 489 MET B C 489 MET B C 1 ATOM 5130 O O . MET B 2 489 ? -10.806 -20.869 -2.281 1.00 89.33 ? 489 MET B O 489 MET B O 1 ATOM 5131 C CB . MET B 2 489 ? -10.112 -18.217 -4.075 1.00 89.33 ? 489 MET B CB 489 MET B CB 1 ATOM 5132 C CG . MET B 2 489 ? -8.965 -17.631 -4.881 1.00 89.33 ? 489 MET B CG 489 MET B CG 1 ATOM 5133 S SD . MET B 2 489 ? -8.613 -15.886 -4.437 1.00 89.33 ? 489 MET B SD 489 MET B SD 1 ATOM 5134 C CE . MET B 2 489 ? -10.118 -15.088 -5.063 1.00 89.33 ? 489 MET B CE 489 MET B CE 1 ATOM 5135 N N . ASN B 2 490 ? -12.565 -20.113 -3.574 1.00 84.81 ? 490 ASN B N 490 ASN B N 1 ATOM 5136 C CA . ASN B 2 490 ? -13.563 -20.575 -2.614 1.00 84.81 ? 490 ASN B CA 490 ASN B CA 1 ATOM 5137 C C . ASN B 2 490 ? -13.789 -22.080 -2.720 1.00 84.81 ? 490 ASN B C 490 ASN B C 1 ATOM 5138 O O . ASN B 2 490 ? -14.084 -22.739 -1.722 1.00 84.81 ? 490 ASN B O 490 ASN B O 1 ATOM 5139 C CB . ASN B 2 490 ? -14.882 -19.824 -2.809 1.00 84.81 ? 490 ASN B CB 490 ASN B CB 1 ATOM 5140 C CG . ASN B 2 490 ? -14.787 -18.364 -2.414 1.00 84.81 ? 490 ASN B CG 490 ASN B CG 1 ATOM 5141 O OD1 . ASN B 2 490 ? -13.911 -17.974 -1.637 1.00 84.81 ? 490 ASN B OD1 490 ASN B OD1 1 ATOM 5142 N ND2 . ASN B 2 490 ? -15.687 -17.546 -2.947 1.00 84.81 ? 490 ASN B ND2 490 ASN B ND2 1 ATOM 5143 N N . SER B 2 491 ? -13.624 -22.656 -3.818 1.00 84.32 ? 491 SER B N 491 SER B N 1 ATOM 5144 C CA . SER B 2 491 ? -13.942 -24.060 -4.056 1.00 84.32 ? 491 SER B CA 491 SER B CA 1 ATOM 5145 C C . SER B 2 491 ? -12.744 -24.957 -3.763 1.00 84.32 ? 491 SER B C 491 SER B C 1 ATOM 5146 O O . SER B 2 491 ? -12.909 -26.128 -3.415 1.00 84.32 ? 491 SER B O 491 SER B O 1 ATOM 5147 C CB . SER B 2 491 ? -14.403 -24.268 -5.500 1.00 84.32 ? 491 SER B CB 491 SER B CB 1 ATOM 5148 O OG . SER B 2 491 ? -13.379 -23.911 -6.411 1.00 84.32 ? 491 SER B OG 491 SER B OG 1 ATOM 5149 N N . THR B 2 492 ? -11.548 -24.374 -3.734 1.00 82.24 ? 492 THR B N 492 THR B N 1 ATOM 5150 C CA . THR B 2 492 ? -10.332 -25.159 -3.553 1.00 82.24 ? 492 THR B CA 492 THR B CA 1 ATOM 5151 C C . THR B 2 492 ? -9.969 -25.262 -2.075 1.00 82.24 ? 492 THR B C 492 THR B C 1 ATOM 5152 O O . THR B 2 492 ? -9.712 -24.248 -1.421 1.00 82.24 ? 492 THR B O 492 THR B O 1 ATOM 5153 C CB . THR B 2 492 ? -9.153 -24.550 -4.333 1.00 82.24 ? 492 THR B CB 492 THR B CB 1 ATOM 5154 O OG1 . THR B 2 492 ? -9.552 -24.320 -5.690 1.00 82.24 ? 492 THR B OG1 492 THR B OG1 1 ATOM 5155 C CG2 . THR B 2 492 ? -7.945 -25.482 -4.322 1.00 82.24 ? 492 THR B CG2 492 THR B CG2 1 ATOM 5156 N N . LYS B 2 493 ? -9.946 -26.408 -1.574 1.00 83.32 ? 493 LYS B N 493 LYS B N 1 ATOM 5157 C CA . LYS B 2 493 ? -9.639 -26.660 -0.169 1.00 83.32 ? 493 LYS B CA 493 LYS B CA 1 ATOM 5158 C C . LYS B 2 493 ? -8.171 -26.373 0.133 1.00 83.32 ? 493 LYS B C 493 LYS B C 1 ATOM 5159 O O . LYS B 2 493 ? -7.821 -26.024 1.262 1.00 83.32 ? 493 LYS B O 493 LYS B O 1 ATOM 5160 C CB . LYS B 2 493 ? -9.978 -28.104 0.204 1.00 83.32 ? 493 LYS B CB 493 LYS B CB 1 ATOM 5161 C CG . LYS B 2 493 ? -11.471 -28.391 0.271 1.00 83.32 ? 493 LYS B CG 493 LYS B CG 1 ATOM 5162 C CD . LYS B 2 493 ? -11.745 -29.816 0.735 1.00 83.32 ? 493 LYS B CD 493 LYS B CD 1 ATOM 5163 C CE . LYS B 2 493 ? -13.237 -30.122 0.753 1.00 83.32 ? 493 LYS B CE 493 LYS B CE 1 ATOM 5164 N NZ . LYS B 2 493 ? -13.510 -31.525 1.185 1.00 83.32 ? 493 LYS B NZ 493 LYS B NZ 1 ATOM 5165 N N . GLU B 2 494 ? -7.335 -26.352 -0.868 1.00 86.26 ? 494 GLU B N 494 GLU B N 1 ATOM 5166 C CA . GLU B 2 494 ? -5.896 -26.176 -0.701 1.00 86.26 ? 494 GLU B CA 494 GLU B CA 1 ATOM 5167 C C . GLU B 2 494 ? -5.519 -24.697 -0.687 1.00 86.26 ? 494 GLU B C 494 GLU B C 1 ATOM 5168 O O . GLU B 2 494 ? -4.356 -24.349 -0.473 1.00 86.26 ? 494 GLU B O 494 GLU B O 1 ATOM 5169 C CB . GLU B 2 494 ? -5.132 -26.903 -1.811 1.00 86.26 ? 494 GLU B CB 494 GLU B CB 1 ATOM 5170 C CG . GLU B 2 494 ? -5.233 -28.419 -1.734 1.00 86.26 ? 494 GLU B CG 494 GLU B CG 1 ATOM 5171 C CD . GLU B 2 494 ? -4.446 -29.129 -2.825 1.00 86.26 ? 494 GLU B CD 494 GLU B CD 1 ATOM 5172 O OE1 . GLU B 2 494 ? -4.616 -30.357 -2.995 1.00 86.26 ? 494 GLU B OE1 494 GLU B OE1 1 ATOM 5173 O OE2 . GLU B 2 494 ? -3.651 -28.450 -3.513 1.00 86.26 ? 494 GLU B OE2 494 GLU B OE2 1 ATOM 5174 N N . SER B 2 495 ? -6.498 -23.837 -0.922 1.00 89.02 ? 495 SER B N 495 SER B N 1 ATOM 5175 C CA . SER B 2 495 ? -6.224 -22.405 -0.872 1.00 89.02 ? 495 SER B CA 495 SER B CA 1 ATOM 5176 C C . SER B 2 495 ? -5.969 -21.940 0.558 1.00 89.02 ? 495 SER B C 495 SER B C 1 ATOM 5177 O O . SER B 2 495 ? -6.699 -22.314 1.477 1.00 89.02 ? 495 SER B O 495 SER B O 1 ATOM 5178 C CB . SER B 2 495 ? -7.388 -21.615 -1.473 1.00 89.02 ? 495 SER B CB 495 SER B CB 1 ATOM 5179 O OG . SER B 2 495 ? -7.170 -20.221 -1.344 1.00 89.02 ? 495 SER B OG 495 SER B OG 1 ATOM 5180 N N . ILE B 2 496 ? -4.841 -21.201 0.712 1.00 91.48 ? 496 ILE B N 496 ILE B N 1 ATOM 5181 C CA . ILE B 2 496 ? -4.484 -20.765 2.058 1.00 91.48 ? 496 ILE B CA 496 ILE B CA 1 ATOM 5182 C C . ILE B 2 496 ? -4.248 -19.257 2.066 1.00 91.48 ? 496 ILE B C 496 ILE B C 1 ATOM 5183 O O . ILE B 2 496 ? -3.874 -18.675 1.045 1.00 91.48 ? 496 ILE B O 496 ILE B O 1 ATOM 5184 C CB . ILE B 2 496 ? -3.232 -21.507 2.578 1.00 91.48 ? 496 ILE B CB 496 ILE B CB 1 ATOM 5185 C CG1 . ILE B 2 496 ? -2.032 -21.237 1.663 1.00 91.48 ? 496 ILE B CG1 496 ILE B CG1 1 ATOM 5186 C CG2 . ILE B 2 496 ? -3.505 -23.010 2.695 1.00 91.48 ? 496 ILE B CG2 496 ILE B CG2 1 ATOM 5187 C CD1 . ILE B 2 496 ? -0.699 -21.690 2.241 1.00 91.48 ? 496 ILE B CD1 496 ILE B CD1 1 ATOM 5188 N N . SER B 2 497 ? -4.492 -18.610 3.234 1.00 92.35 ? 497 SER B N 497 SER B N 1 ATOM 5189 C CA . SER B 2 497 ? -4.179 -17.198 3.429 1.00 92.35 ? 497 SER B CA 497 SER B CA 1 ATOM 5190 C C . SER B 2 497 ? -2.708 -17.001 3.780 1.00 92.35 ? 497 SER B C 497 SER B C 1 ATOM 5191 O O . SER B 2 497 ? -2.130 -17.797 4.523 1.00 92.35 ? 497 SER B O 497 SER B O 1 ATOM 5192 C CB . SER B 2 497 ? -5.059 -16.601 4.528 1.00 92.35 ? 497 SER B CB 497 SER B CB 1 ATOM 5193 O OG . SER B 2 497 ? -6.429 -16.686 4.177 1.00 92.35 ? 497 SER B OG 497 SER B OG 1 ATOM 5194 N N . LEU B 2 498 ? -2.125 -15.960 3.199 1.00 94.69 ? 498 LEU B N 498 LEU B N 1 ATOM 5195 C CA . LEU B 2 498 ? -0.698 -15.711 3.376 1.00 94.69 ? 498 LEU B CA 498 LEU B CA 1 ATOM 5196 C C . LEU B 2 498 ? -0.464 -14.422 4.157 1.00 94.69 ? 498 LEU B C 498 LEU B C 1 ATOM 5197 O O . LEU B 2 498 ? -1.118 -13.408 3.901 1.00 94.69 ? 498 LEU B O 498 LEU B O 1 ATOM 5198 C CB . LEU B 2 498 ? 0.005 -15.633 2.019 1.00 94.69 ? 498 LEU B CB 498 LEU B CB 1 ATOM 5199 C CG . LEU B 2 498 ? -0.070 -16.886 1.144 1.00 94.69 ? 498 LEU B CG 498 LEU B CG 1 ATOM 5200 C CD1 . LEU B 2 498 ? 0.446 -16.584 -0.259 1.00 94.69 ? 498 LEU B CD1 498 LEU B CD1 1 ATOM 5201 C CD2 . LEU B 2 498 ? 0.720 -18.027 1.776 1.00 94.69 ? 498 LEU B CD2 498 LEU B CD2 1 ATOM 5202 N N . PRO B 2 499 ? 0.486 -14.492 5.112 1.00 94.97 ? 499 PRO B N 499 PRO B N 1 ATOM 5203 C CA . PRO B 2 499 ? 0.875 -13.242 5.770 1.00 94.97 ? 499 PRO B CA 499 PRO B CA 1 ATOM 5204 C C . PRO B 2 499 ? 1.627 -12.295 4.838 1.00 94.97 ? 499 PRO B C 499 PRO B C 1 ATOM 5205 O O . PRO B 2 499 ? 2.488 -12.733 4.070 1.00 94.97 ? 499 PRO B O 499 PRO B O 1 ATOM 5206 C CB . PRO B 2 499 ? 1.775 -13.711 6.915 1.00 94.97 ? 499 PRO B CB 499 PRO B CB 1 ATOM 5207 C CG . PRO B 2 499 ? 2.355 -15.005 6.440 1.00 94.97 ? 499 PRO B CG 499 PRO B CG 1 ATOM 5208 C CD . PRO B 2 499 ? 1.340 -15.692 5.572 1.00 94.97 ? 499 PRO B CD 499 PRO B CD 1 ATOM 5209 N N . VAL B 2 500 ? 1.292 -11.014 4.934 1.00 96.74 ? 500 VAL B N 500 VAL B N 1 ATOM 5210 C CA . VAL B 2 500 ? 1.839 -10.035 4.001 1.00 96.74 ? 500 VAL B CA 500 VAL B CA 1 ATOM 5211 C C . VAL B 2 500 ? 2.636 -8.980 4.766 1.00 96.74 ? 500 VAL B C 500 VAL B C 1 ATOM 5212 O O . VAL B 2 500 ? 2.184 -8.481 5.799 1.00 96.74 ? 500 VAL B O 500 VAL B O 1 ATOM 5213 C CB . VAL B 2 500 ? 0.726 -9.361 3.167 1.00 96.74 ? 500 VAL B CB 500 VAL B CB 1 ATOM 5214 C CG1 . VAL B 2 500 ? 1.313 -8.295 2.244 1.00 96.74 ? 500 VAL B CG1 500 VAL B CG1 1 ATOM 5215 C CG2 . VAL B 2 500 ? -0.042 -10.407 2.361 1.00 96.74 ? 500 VAL B CG2 500 VAL B CG2 1 ATOM 5216 N N . ALA B 2 501 ? 3.774 -8.709 4.300 1.00 97.44 ? 501 ALA B N 501 ALA B N 1 ATOM 5217 C CA . ALA B 2 501 ? 4.567 -7.570 4.756 1.00 97.44 ? 501 ALA B CA 501 ALA B CA 1 ATOM 5218 C C . ALA B 2 501 ? 4.597 -6.466 3.702 1.00 97.44 ? 501 ALA B C 501 ALA B C 1 ATOM 5219 O O . ALA B 2 501 ? 4.748 -6.742 2.510 1.00 97.44 ? 501 ALA B O 501 ALA B O 1 ATOM 5220 C CB . ALA B 2 501 ? 5.987 -8.013 5.098 1.00 97.44 ? 501 ALA B CB 501 ALA B CB 1 ATOM 5221 N N . ARG B 2 502 ? 4.453 -5.222 4.153 1.00 96.84 ? 502 ARG B N 502 ARG B N 1 ATOM 5222 C CA . ARG B 2 502 ? 4.335 -4.113 3.213 1.00 96.84 ? 502 ARG B CA 502 ARG B CA 1 ATOM 5223 C C . ARG B 2 502 ? 5.275 -2.973 3.589 1.00 96.84 ? 502 ARG B C 502 ARG B C 1 ATOM 5224 O O . ARG B 2 502 ? 5.323 -2.558 4.749 1.00 96.84 ? 502 ARG B O 502 ARG B O 1 ATOM 5225 C CB . ARG B 2 502 ? 2.892 -3.606 3.158 1.00 96.84 ? 502 ARG B CB 502 ARG B CB 1 ATOM 5226 C CG . ARG B 2 502 ? 2.680 -2.452 2.191 1.00 96.84 ? 502 ARG B CG 502 ARG B CG 1 ATOM 5227 C CD . ARG B 2 502 ? 1.250 -1.934 2.235 1.00 96.84 ? 502 ARG B CD 502 ARG B CD 1 ATOM 5228 N NE . ARG B 2 502 ? 1.046 -0.833 1.298 1.00 96.84 ? 502 ARG B NE 502 ARG B NE 1 ATOM 5229 C CZ . ARG B 2 502 ? -0.000 -0.012 1.309 1.00 96.84 ? 502 ARG B CZ 502 ARG B CZ 1 ATOM 5230 N NH1 . ARG B 2 502 ? -0.962 -0.151 2.215 1.00 96.84 ? 502 ARG B NH1 502 ARG B NH1 1 ATOM 5231 N NH2 . ARG B 2 502 ? -0.086 0.957 0.409 1.00 96.84 ? 502 ARG B NH2 502 ARG B NH2 1 ATOM 5232 N N . GLU B 2 503 ? 6.014 -2.460 2.672 1.00 97.01 ? 503 GLU B N 503 GLU B N 1 ATOM 5233 C CA . GLU B 2 503 ? 6.822 -1.250 2.792 1.00 97.01 ? 503 GLU B CA 503 GLU B CA 1 ATOM 5234 C C . GLU B 2 503 ? 6.522 -0.271 1.660 1.00 97.01 ? 503 GLU B C 503 GLU B C 1 ATOM 5235 O O . GLU B 2 503 ? 6.545 -0.646 0.486 1.00 97.01 ? 503 GLU B O 503 GLU B O 1 ATOM 5236 C CB . GLU B 2 503 ? 8.313 -1.598 2.805 1.00 97.01 ? 503 GLU B CB 503 GLU B CB 1 ATOM 5237 C CG . GLU B 2 503 ? 8.740 -2.432 4.005 1.00 97.01 ? 503 GLU B CG 503 GLU B CG 1 ATOM 5238 C CD . GLU B 2 503 ? 8.739 -1.650 5.309 1.00 97.01 ? 503 GLU B CD 503 GLU B CD 1 ATOM 5239 O OE1 . GLU B 2 503 ? 8.824 -2.275 6.391 1.00 97.01 ? 503 GLU B OE1 503 GLU B OE1 1 ATOM 5240 O OE2 . GLU B 2 503 ? 8.652 -0.404 5.249 1.00 97.01 ? 503 GLU B OE2 503 GLU B OE2 1 ATOM 5241 N N . CYS B 2 504 ? 6.201 0.967 2.063 1.00 95.86 ? 504 CYS B N 504 CYS B N 1 ATOM 5242 C CA . CYS B 2 504 ? 5.859 2.008 1.099 1.00 95.86 ? 504 CYS B CA 504 CYS B CA 1 ATOM 5243 C C . CYS B 2 504 ? 6.593 3.306 1.414 1.00 95.86 ? 504 CYS B C 504 CYS B C 1 ATOM 5244 O O . CYS B 2 504 ? 6.551 3.788 2.548 1.00 95.86 ? 504 CYS B O 504 CYS B O 1 ATOM 5245 C CB . CYS B 2 504 ? 4.351 2.253 1.089 1.00 95.86 ? 504 CYS B CB 504 CYS B CB 1 ATOM 5246 S SG . CYS B 2 504 ? 3.839 3.596 -0.005 1.00 95.86 ? 504 CYS B SG 504 CYS B SG 1 ATOM 5247 N N . ASN B 2 505 ? 7.289 3.845 0.388 1.00 95.29 ? 505 ASN B N 505 ASN B N 1 ATOM 5248 C CA . ASN B 2 505 ? 8.019 5.101 0.517 1.00 95.29 ? 505 ASN B CA 505 ASN B CA 1 ATOM 5249 C C . ASN B 2 505 ? 7.734 6.039 -0.653 1.00 95.29 ? 505 ASN B C 505 ASN B C 1 ATOM 5250 O O . ASN B 2 505 ? 7.501 5.585 -1.775 1.00 95.29 ? 505 ASN B O 505 ASN B O 1 ATOM 5251 C CB . ASN B 2 505 ? 9.522 4.839 0.634 1.00 95.29 ? 505 ASN B CB 505 ASN B CB 1 ATOM 5252 C CG . ASN B 2 505 ? 9.880 4.030 1.865 1.00 95.29 ? 505 ASN B CG 505 ASN B CG 1 ATOM 5253 O OD1 . ASN B 2 505 ? 9.022 3.737 2.701 1.00 95.29 ? 505 ASN B OD1 505 ASN B OD1 1 ATOM 5254 N ND2 . ASN B 2 505 ? 11.150 3.662 1.984 1.00 95.29 ? 505 ASN B ND2 505 ASN B ND2 1 ATOM 5255 N N . THR B 2 506 ? 7.690 7.257 -0.294 1.00 95.28 ? 506 THR B N 506 THR B N 1 ATOM 5256 C CA . THR B 2 506 ? 7.639 8.284 -1.329 1.00 95.28 ? 506 THR B CA 506 THR B CA 1 ATOM 5257 C C . THR B 2 506 ? 8.984 8.996 -1.452 1.00 95.28 ? 506 THR B C 506 THR B C 1 ATOM 5258 O O . THR B 2 506 ? 9.507 9.520 -0.466 1.00 95.28 ? 506 THR B O 506 THR B O 1 ATOM 5259 C CB . THR B 2 506 ? 6.534 9.316 -1.038 1.00 95.28 ? 506 THR B CB 506 THR B CB 1 ATOM 5260 O OG1 . THR B 2 506 ? 5.291 8.632 -0.835 1.00 95.28 ? 506 THR B OG1 506 THR B OG1 1 ATOM 5261 C CG2 . THR B 2 506 ? 6.378 10.296 -2.196 1.00 95.28 ? 506 THR B CG2 506 THR B CG2 1 ATOM 5262 N N . ILE B 2 507 ? 9.479 9.007 -2.743 1.00 95.58 ? 507 ILE B N 507 ILE B N 1 ATOM 5263 C CA . ILE B 2 507 ? 10.803 9.591 -2.925 1.00 95.58 ? 507 ILE B CA 507 ILE B CA 1 ATOM 5264 C C . ILE B 2 507 ? 10.762 10.626 -4.047 1.00 95.58 ? 507 ILE B C 507 ILE B C 1 ATOM 5265 O O . ILE B 2 507 ? 9.907 10.555 -4.933 1.00 95.58 ? 507 ILE B O 507 ILE B O 1 ATOM 5266 C CB . ILE B 2 507 ? 11.861 8.507 -3.234 1.00 95.58 ? 507 ILE B CB 507 ILE B CB 1 ATOM 5267 C CG1 . ILE B 2 507 ? 11.516 7.782 -4.540 1.00 95.58 ? 507 ILE B CG1 507 ILE B CG1 1 ATOM 5268 C CG2 . ILE B 2 507 ? 11.975 7.517 -2.072 1.00 95.58 ? 507 ILE B CG2 507 ILE B CG2 1 ATOM 5269 C CD1 . ILE B 2 507 ? 12.652 6.936 -5.097 1.00 95.58 ? 507 ILE B CD1 507 ILE B CD1 1 ATOM 5270 N N . VAL B 2 508 ? 11.669 11.567 -3.901 1.00 95.08 ? 508 VAL B N 508 VAL B N 1 ATOM 5271 C CA . VAL B 2 508 ? 11.791 12.619 -4.906 1.00 95.08 ? 508 VAL B CA 508 VAL B CA 1 ATOM 5272 C C . VAL B 2 508 ? 13.200 12.610 -5.495 1.00 95.08 ? 508 VAL B C 508 VAL B C 1 ATOM 5273 O O . VAL B 2 508 ? 14.188 12.642 -4.757 1.00 95.08 ? 508 VAL B O 508 VAL B O 1 ATOM 5274 C CB . VAL B 2 508 ? 11.470 14.009 -4.314 1.00 95.08 ? 508 VAL B CB 508 VAL B CB 1 ATOM 5275 C CG1 . VAL B 2 508 ? 11.558 15.088 -5.392 1.00 95.08 ? 508 VAL B CG1 508 VAL B CG1 1 ATOM 5276 C CG2 . VAL B 2 508 ? 10.085 14.007 -3.669 1.00 95.08 ? 508 VAL B CG2 508 VAL B CG2 1 ATOM 5277 N N . LEU B 2 509 ? 13.272 12.568 -6.823 1.00 94.53 ? 509 LEU B N 509 LEU B N 1 ATOM 5278 C CA . LEU B 2 509 ? 14.550 12.641 -7.521 1.00 94.53 ? 509 LEU B CA 509 LEU B CA 1 ATOM 5279 C C . LEU B 2 509 ? 14.908 14.085 -7.854 1.00 94.53 ? 509 LEU B C 509 LEU B C 1 ATOM 5280 O O . LEU B 2 509 ? 14.429 14.635 -8.849 1.00 94.53 ? 509 LEU B O 509 LEU B O 1 ATOM 5281 C CB . LEU B 2 509 ? 14.509 11.805 -8.804 1.00 94.53 ? 509 LEU B CB 509 LEU B CB 1 ATOM 5282 C CG . LEU B 2 509 ? 14.184 10.320 -8.635 1.00 94.53 ? 509 LEU B CG 509 LEU B CG 1 ATOM 5283 C CD1 . LEU B 2 509 ? 13.969 9.666 -9.996 1.00 94.53 ? 509 LEU B CD1 509 LEU B CD1 1 ATOM 5284 C CD2 . LEU B 2 509 ? 15.296 9.613 -7.866 1.00 94.53 ? 509 LEU B CD2 509 LEU B CD2 1 ATOM 5285 N N . CYS B 2 510 ? 15.788 14.643 -7.021 1.00 93.16 ? 510 CYS B N 510 CYS B N 1 ATOM 5286 C CA . CYS B 2 510 ? 16.140 16.053 -7.143 1.00 93.16 ? 510 CYS B CA 510 CYS B CA 1 ATOM 5287 C C . CYS B 2 510 ? 17.359 16.236 -8.039 1.00 93.16 ? 510 CYS B C 510 CYS B C 1 ATOM 5288 O O . CYS B 2 510 ? 18.429 15.693 -7.757 1.00 93.16 ? 510 CYS B O 510 CYS B O 1 ATOM 5289 C CB . CYS B 2 510 ? 16.412 16.658 -5.766 1.00 93.16 ? 510 CYS B CB 510 CYS B CB 1 ATOM 5290 S SG . CYS B 2 510 ? 14.998 16.583 -4.645 1.00 93.16 ? 510 CYS B SG 510 CYS B SG 1 ATOM 5291 N N . ASP B 2 511 ? 17.098 16.973 -9.016 1.00 90.50 ? 511 ASP B N 511 ASP B N 1 ATOM 5292 C CA . ASP B 2 511 ? 18.217 17.321 -9.886 1.00 90.50 ? 511 ASP B CA 511 ASP B CA 1 ATOM 5293 C C . ASP B 2 511 ? 19.118 18.366 -9.230 1.00 90.50 ? 511 ASP B C 511 ASP B C 1 ATOM 5294 O O . ASP B 2 511 ? 18.788 18.898 -8.168 1.00 90.50 ? 511 ASP B O 511 ASP B O 1 ATOM 5295 C CB . ASP B 2 511 ? 17.710 17.836 -11.234 1.00 90.50 ? 511 ASP B CB 511 ASP B CB 1 ATOM 5296 C CG . ASP B 2 511 ? 18.804 17.928 -12.284 1.00 90.50 ? 511 ASP B CG 511 ASP B CG 1 ATOM 5297 O OD1 . ASP B 2 511 ? 19.957 17.540 -11.998 1.00 90.50 ? 511 ASP B OD1 511 ASP B OD1 1 ATOM 5298 O OD2 . ASP B 2 511 ? 18.510 18.396 -13.405 1.00 90.50 ? 511 ASP B OD2 511 ASP B OD2 1 ATOM 5299 N N . SER B 2 512 ? 20.228 18.716 -9.839 1.00 87.80 ? 512 SER B N 512 SER B N 1 ATOM 5300 C CA . SER B 2 512 ? 21.188 19.667 -9.289 1.00 87.80 ? 512 SER B CA 512 SER B CA 1 ATOM 5301 C C . SER B 2 512 ? 20.576 21.059 -9.160 1.00 87.80 ? 512 SER B C 512 SER B C 1 ATOM 5302 O O . SER B 2 512 ? 20.951 21.828 -8.273 1.00 87.80 ? 512 SER B O 512 SER B O 1 ATOM 5303 C CB . SER B 2 512 ? 22.441 19.731 -10.162 1.00 87.80 ? 512 SER B CB 512 SER B CB 1 ATOM 5304 O OG . SER B 2 512 ? 22.102 20.021 -11.508 1.00 87.80 ? 512 SER B OG 512 SER B OG 1 ATOM 5305 N N . SER B 2 513 ? 19.584 21.395 -9.894 1.00 85.41 ? 513 SER B N 513 SER B N 1 ATOM 5306 C CA . SER B 2 513 ? 18.967 22.718 -9.931 1.00 85.41 ? 513 SER B CA 513 SER B CA 1 ATOM 5307 C C . SER B 2 513 ? 18.054 22.935 -8.729 1.00 85.41 ? 513 SER B C 513 SER B C 1 ATOM 5308 O O . SER B 2 513 ? 17.885 24.065 -8.267 1.00 85.41 ? 513 SER B O 513 SER B O 1 ATOM 5309 C CB . SER B 2 513 ? 18.174 22.904 -11.225 1.00 85.41 ? 513 SER B CB 513 SER B CB 1 ATOM 5310 O OG . SER B 2 513 ? 17.107 21.974 -11.299 1.00 85.41 ? 513 SER B OG 513 SER B OG 1 ATOM 5311 N N . VAL B 2 514 ? 17.533 21.946 -8.196 1.00 84.11 ? 514 VAL B N 514 VAL B N 1 ATOM 5312 C CA . VAL B 2 514 ? 16.530 22.058 -7.142 1.00 84.11 ? 514 VAL B CA 514 VAL B CA 1 ATOM 5313 C C . VAL B 2 514 ? 17.151 21.691 -5.797 1.00 84.11 ? 514 VAL B C 514 VAL B C 1 ATOM 5314 O O . VAL B 2 514 ? 16.679 22.133 -4.747 1.00 84.11 ? 514 VAL B O 514 VAL B O 1 ATOM 5315 C CB . VAL B 2 514 ? 15.305 21.160 -7.427 1.00 84.11 ? 514 VAL B CB 514 VAL B CB 1 ATOM 5316 C CG1 . VAL B 2 514 ? 14.261 21.303 -6.320 1.00 84.11 ? 514 VAL B CG1 514 VAL B CG1 1 ATOM 5317 C CG2 . VAL B 2 514 ? 14.697 21.502 -8.786 1.00 84.11 ? 514 VAL B CG2 514 VAL B CG2 1 ATOM 5318 N N . SER B 2 515 ? 18.224 21.032 -5.866 1.00 80.73 ? 515 SER B N 515 SER B N 1 ATOM 5319 C CA . SER B 2 515 ? 18.854 20.555 -4.639 1.00 80.73 ? 515 SER B CA 515 SER B CA 1 ATOM 5320 C C . SER B 2 515 ? 19.530 21.695 -3.886 1.00 80.73 ? 515 SER B C 515 SER B C 1 ATOM 5321 O O . SER B 2 515 ? 19.986 22.665 -4.496 1.00 80.73 ? 515 SER B O 515 SER B O 1 ATOM 5322 C CB . SER B 2 515 ? 19.877 19.462 -4.952 1.00 80.73 ? 515 SER B CB 515 SER B CB 1 ATOM 5323 O OG . SER B 2 515 ? 20.640 19.143 -3.801 1.00 80.73 ? 515 SER B OG 515 SER B OG 1 ATOM 5324 N N . THR B 2 516 ? 19.503 21.672 -2.572 1.00 77.17 ? 516 THR B N 516 THR B N 1 ATOM 5325 C CA . THR B 2 516 ? 20.108 22.689 -1.718 1.00 77.17 ? 516 THR B CA 516 THR B CA 1 ATOM 5326 C C . THR B 2 516 ? 21.629 22.659 -1.835 1.00 77.17 ? 516 THR B C 516 THR B C 1 ATOM 5327 O O . THR B 2 516 ? 22.285 23.698 -1.736 1.00 77.17 ? 516 THR B O 516 THR B O 1 ATOM 5328 C CB . THR B 2 516 ? 19.699 22.496 -0.246 1.00 77.17 ? 516 THR B CB 516 THR B CB 1 ATOM 5329 O OG1 . THR B 2 516 ? 19.961 21.143 0.144 1.00 77.17 ? 516 THR B OG1 516 THR B OG1 1 ATOM 5330 C CG2 . THR B 2 516 ? 18.217 22.794 -0.042 1.00 77.17 ? 516 THR B CG2 516 THR B CG2 1 ATOM 5331 N N . THR B 2 517 ? 22.230 21.462 -2.155 1.00 80.09 ? 517 THR B N 517 THR B N 1 ATOM 5332 C CA . THR B 2 517 ? 23.675 21.266 -2.157 1.00 80.09 ? 517 THR B CA 517 THR B CA 1 ATOM 5333 C C . THR B 2 517 ? 24.232 21.369 -3.574 1.00 80.09 ? 517 THR B C 517 THR B C 1 ATOM 5334 O O . THR B 2 517 ? 25.419 21.123 -3.800 1.00 80.09 ? 517 THR B O 517 THR B O 1 ATOM 5335 C CB . THR B 2 517 ? 24.055 19.902 -1.552 1.00 80.09 ? 517 THR B CB 517 THR B CB 1 ATOM 5336 O OG1 . THR B 2 517 ? 23.381 18.862 -2.271 1.00 80.09 ? 517 THR B OG1 517 THR B OG1 1 ATOM 5337 C CG2 . THR B 2 517 ? 23.661 19.825 -0.080 1.00 80.09 ? 517 THR B CG2 517 THR B CG2 1 ATOM 5338 N N . ASP B 2 518 ? 23.498 21.792 -4.524 1.00 81.82 ? 518 ASP B N 518 ASP B N 1 ATOM 5339 C CA . ASP B 2 518 ? 23.923 21.899 -5.916 1.00 81.82 ? 518 ASP B CA 518 ASP B CA 1 ATOM 5340 C C . ASP B 2 518 ? 24.418 20.555 -6.445 1.00 81.82 ? 518 ASP B C 518 ASP B C 1 ATOM 5341 O O . ASP B 2 518 ? 25.200 20.505 -7.396 1.00 81.82 ? 518 ASP B O 518 ASP B O 1 ATOM 5342 C CB . ASP B 2 518 ? 25.019 22.957 -6.063 1.00 81.82 ? 518 ASP B CB 518 ASP B CB 1 ATOM 5343 C CG . ASP B 2 518 ? 24.501 24.375 -5.895 1.00 81.82 ? 518 ASP B CG 518 ASP B CG 1 ATOM 5344 O OD1 . ASP B 2 518 ? 23.310 24.627 -6.179 1.00 81.82 ? 518 ASP B OD1 518 ASP B OD1 1 ATOM 5345 O OD2 . ASP B 2 518 ? 25.291 25.248 -5.477 1.00 81.82 ? 518 ASP B OD2 518 ASP B OD2 1 ATOM 5346 N N . ARG B 2 519 ? 24.219 19.494 -5.754 1.00 87.36 ? 519 ARG B N 519 ARG B N 1 ATOM 5347 C CA . ARG B 2 519 ? 24.469 18.129 -6.207 1.00 87.36 ? 519 ARG B CA 519 ARG B CA 1 ATOM 5348 C C . ARG B 2 519 ? 23.171 17.332 -6.285 1.00 87.36 ? 519 ARG B C 519 ARG B C 1 ATOM 5349 O O . ARG B 2 519 ? 22.249 17.559 -5.499 1.00 87.36 ? 519 ARG B O 519 ARG B O 1 ATOM 5350 C CB . ARG B 2 519 ? 25.460 17.427 -5.276 1.00 87.36 ? 519 ARG B CB 519 ARG B CB 1 ATOM 5351 C CG . ARG B 2 519 ? 26.856 18.028 -5.297 1.00 87.36 ? 519 ARG B CG 519 ARG B CG 1 ATOM 5352 C CD . ARG B 2 519 ? 27.826 17.233 -4.434 1.00 87.36 ? 519 ARG B CD 519 ARG B CD 1 ATOM 5353 N NE . ARG B 2 519 ? 29.155 17.836 -4.420 1.00 87.36 ? 519 ARG B NE 519 ARG B NE 1 ATOM 5354 C CZ . ARG B 2 519 ? 30.188 17.377 -3.719 1.00 87.36 ? 519 ARG B CZ 519 ARG B CZ 1 ATOM 5355 N NH1 . ARG B 2 519 ? 30.065 16.297 -2.956 1.00 87.36 ? 519 ARG B NH1 519 ARG B NH1 1 ATOM 5356 N NH2 . ARG B 2 519 ? 31.354 18.004 -3.780 1.00 87.36 ? 519 ARG B NH2 519 ARG B NH2 1 ATOM 5357 N N . PRO B 2 520 ? 23.097 16.506 -7.366 1.00 90.18 ? 520 PRO B N 520 PRO B N 1 ATOM 5358 C CA . PRO B 2 520 ? 21.887 15.684 -7.447 1.00 90.18 ? 520 PRO B CA 520 PRO B CA 1 ATOM 5359 C C . PRO B 2 520 ? 21.719 14.762 -6.241 1.00 90.18 ? 520 PRO B C 520 PRO B C 1 ATOM 5360 O O . PRO B 2 520 ? 22.685 14.136 -5.799 1.00 90.18 ? 520 PRO B O 520 PRO B O 1 ATOM 5361 C CB . PRO B 2 520 ? 22.097 14.874 -8.729 1.00 90.18 ? 520 PRO B CB 520 PRO B CB 1 ATOM 5362 C CG . PRO B 2 520 ? 23.579 14.823 -8.911 1.00 90.18 ? 520 PRO B CG 520 PRO B CG 1 ATOM 5363 C CD . PRO B 2 520 ? 24.176 16.066 -8.316 1.00 90.18 ? 520 PRO B CD 520 PRO B CD 1 ATOM 5364 N N . GLU B 2 521 ? 20.565 14.798 -5.716 1.00 93.13 ? 521 GLU B N 521 GLU B N 1 ATOM 5365 C CA . GLU B 2 521 ? 20.299 13.970 -4.543 1.00 93.13 ? 521 GLU B CA 521 GLU B CA 1 ATOM 5366 C C . GLU B 2 521 ? 18.883 13.402 -4.579 1.00 93.13 ? 521 GLU B C 521 GLU B C 1 ATOM 5367 O O . GLU B 2 521 ? 17.993 13.978 -5.207 1.00 93.13 ? 521 GLU B O 521 GLU B O 1 ATOM 5368 C CB . GLU B 2 521 ? 20.511 14.774 -3.258 1.00 93.13 ? 521 GLU B CB 521 GLU B CB 1 ATOM 5369 C CG . GLU B 2 521 ? 19.517 15.912 -3.073 1.00 93.13 ? 521 GLU B CG 521 GLU B CG 1 ATOM 5370 C CD . GLU B 2 521 ? 19.769 16.730 -1.816 1.00 93.13 ? 521 GLU B CD 521 GLU B CD 1 ATOM 5371 O OE1 . GLU B 2 521 ? 18.942 17.612 -1.491 1.00 93.13 ? 521 GLU B OE1 521 GLU B OE1 1 ATOM 5372 O OE2 . GLU B 2 521 ? 20.801 16.487 -1.152 1.00 93.13 ? 521 GLU B OE2 521 GLU B OE2 1 ATOM 5373 N N . LEU B 2 522 ? 18.784 12.245 -3.998 1.00 94.76 ? 522 LEU B N 522 LEU B N 1 ATOM 5374 C CA . LEU B 2 522 ? 17.471 11.649 -3.775 1.00 94.76 ? 522 LEU B CA 522 LEU B CA 1 ATOM 5375 C C . LEU B 2 522 ? 16.936 12.013 -2.394 1.00 94.76 ? 522 LEU B C 522 LEU B C 1 ATOM 5376 O O . LEU B 2 522 ? 17.625 11.826 -1.388 1.00 94.76 ? 522 LEU B O 522 LEU B O 1 ATOM 5377 C CB . LEU B 2 522 ? 17.541 10.127 -3.924 1.00 94.76 ? 522 LEU B CB 522 LEU B CB 1 ATOM 5378 C CG . LEU B 2 522 ? 16.215 9.373 -3.810 1.00 94.76 ? 522 LEU B CG 522 LEU B CG 1 ATOM 5379 C CD1 . LEU B 2 522 ? 16.221 8.150 -4.720 1.00 94.76 ? 522 LEU B CD1 522 LEU B CD1 1 ATOM 5380 C CD2 . LEU B 2 522 ? 15.952 8.969 -2.364 1.00 94.76 ? 522 LEU B CD2 522 LEU B CD2 1 ATOM 5381 N N . LEU B 2 523 ? 15.794 12.647 -2.359 1.00 94.56 ? 523 LEU B N 523 LEU B N 1 ATOM 5382 C CA . LEU B 2 523 ? 15.137 13.002 -1.105 1.00 94.56 ? 523 LEU B CA 523 LEU B CA 1 ATOM 5383 C C . LEU B 2 523 ? 14.055 11.987 -0.752 1.00 94.56 ? 523 LEU B C 523 LEU B C 1 ATOM 5384 O O . LEU B 2 523 ? 13.061 11.857 -1.470 1.00 94.56 ? 523 LEU B O 523 LEU B O 1 ATOM 5385 C CB . LEU B 2 523 ? 14.528 14.403 -1.197 1.00 94.56 ? 523 LEU B CB 523 LEU B CB 1 ATOM 5386 C CG . LEU B 2 523 ? 13.806 14.912 0.052 1.00 94.56 ? 523 LEU B CG 523 LEU B CG 1 ATOM 5387 C CD1 . LEU B 2 523 ? 14.788 15.055 1.211 1.00 94.56 ? 523 LEU B CD1 523 LEU B CD1 1 ATOM 5388 C CD2 . LEU B 2 523 ? 13.112 16.239 -0.234 1.00 94.56 ? 523 LEU B CD2 523 LEU B CD2 1 ATOM 5389 N N . ARG B 2 524 ? 14.257 11.298 0.305 1.00 94.63 ? 524 ARG B N 524 ARG B N 1 ATOM 5390 C CA . ARG B 2 524 ? 13.255 10.380 0.838 1.00 94.63 ? 524 ARG B CA 524 ARG B CA 1 ATOM 5391 C C . ARG B 2 524 ? 12.252 11.116 1.719 1.00 94.63 ? 524 ARG B C 524 ARG B C 1 ATOM 5392 O O . ARG B 2 524 ? 12.557 11.458 2.864 1.00 94.63 ? 524 ARG B O 524 ARG B O 1 ATOM 5393 C CB . ARG B 2 524 ? 13.924 9.256 1.631 1.00 94.63 ? 524 ARG B CB 524 ARG B CB 1 ATOM 5394 C CG . ARG B 2 524 ? 13.021 8.061 1.888 1.00 94.63 ? 524 ARG B CG 524 ARG B CG 1 ATOM 5395 C CD . ARG B 2 524 ? 13.793 6.883 2.467 1.00 94.63 ? 524 ARG B CD 524 ARG B CD 1 ATOM 5396 N NE . ARG B 2 524 ? 12.918 5.748 2.743 1.00 94.63 ? 524 ARG B NE 524 ARG B NE 1 ATOM 5397 C CZ . ARG B 2 524 ? 13.328 4.570 3.204 1.00 94.63 ? 524 ARG B CZ 524 ARG B CZ 1 ATOM 5398 N NH1 . ARG B 2 524 ? 14.614 4.348 3.451 1.00 94.63 ? 524 ARG B NH1 524 ARG B NH1 1 ATOM 5399 N NH2 . ARG B 2 524 ? 12.445 3.605 3.421 1.00 94.63 ? 524 ARG B NH2 524 ARG B NH2 1 ATOM 5400 N N . LEU B 2 525 ? 11.039 11.321 1.175 1.00 94.08 ? 525 LEU B N 525 LEU B N 1 ATOM 5401 C CA . LEU B 2 525 ? 10.020 12.059 1.912 1.00 94.08 ? 525 LEU B CA 525 LEU B CA 1 ATOM 5402 C C . LEU B 2 525 ? 9.515 11.248 3.101 1.00 94.08 ? 525 LEU B C 525 LEU B C 1 ATOM 5403 O O . LEU B 2 525 ? 9.275 11.800 4.177 1.00 94.08 ? 525 LEU B O 525 LEU B O 1 ATOM 5404 C CB . LEU B 2 525 ? 8.850 12.422 0.993 1.00 94.08 ? 525 LEU B CB 525 LEU B CB 1 ATOM 5405 C CG . LEU B 2 525 ? 9.166 13.370 -0.164 1.00 94.08 ? 525 LEU B CG 525 LEU B CG 1 ATOM 5406 C CD1 . LEU B 2 525 ? 7.954 13.515 -1.077 1.00 94.08 ? 525 LEU B CD1 525 LEU B CD1 1 ATOM 5407 C CD2 . LEU B 2 525 ? 9.608 14.731 0.365 1.00 94.08 ? 525 LEU B CD2 525 LEU B CD2 1 ATOM 5408 N N . THR B 2 526 ? 9.206 10.018 2.820 1.00 93.32 ? 526 THR B N 526 THR B N 1 ATOM 5409 C CA . THR B 2 526 ? 8.726 9.113 3.857 1.00 93.32 ? 526 THR B CA 526 THR B CA 1 ATOM 5410 C C . THR B 2 526 ? 9.597 7.862 3.929 1.00 93.32 ? 526 THR B C 526 THR B C 1 ATOM 5411 O O . THR B 2 526 ? 10.238 7.488 2.945 1.00 93.32 ? 526 THR B O 526 THR B O 1 ATOM 5412 C CB . THR B 2 526 ? 7.261 8.707 3.610 1.00 93.32 ? 526 THR B CB 526 THR B CB 1 ATOM 5413 O OG1 . THR B 2 526 ? 7.156 8.072 2.330 1.00 93.32 ? 526 THR B OG1 526 THR B OG1 1 ATOM 5414 C CG2 . THR B 2 526 ? 6.341 9.923 3.638 1.00 93.32 ? 526 THR B CG2 526 THR B CG2 1 ATOM 5415 N N . GLY B 2 527 ? 9.631 7.328 5.098 1.00 87.77 ? 527 GLY B N 527 GLY B N 1 ATOM 5416 C CA . GLY B 2 527 ? 10.460 6.150 5.304 1.00 87.77 ? 527 GLY B CA 527 GLY B CA 1 ATOM 5417 C C . GLY B 2 527 ? 11.876 6.485 5.734 1.00 87.77 ? 527 GLY B C 527 GLY B C 1 ATOM 5418 O O . GLY B 2 527 ? 12.124 7.557 6.290 1.00 87.77 ? 527 GLY B O 527 GLY B O 1 ATOM 5419 N N . GLY B 2 528 ? 12.701 5.459 5.858 1.00 84.43 ? 528 GLY B N 528 GLY B N 1 ATOM 5420 C CA . GLY B 2 528 ? 14.099 5.658 6.207 1.00 84.43 ? 528 GLY B CA 528 GLY B CA 1 ATOM 5421 C C . GLY B 2 528 ? 14.487 4.998 7.517 1.00 84.43 ? 528 GLY B C 528 GLY B C 1 ATOM 5422 O O . GLY B 2 528 ? 13.682 4.288 8.123 1.00 84.43 ? 528 GLY B O 528 GLY B O 1 ATOM 5423 N N . SER B 2 529 ? 15.719 5.246 7.845 1.00 85.86 ? 529 SER B N 529 SER B N 1 ATOM 5424 C CA . SER B 2 529 ? 16.307 4.545 8.981 1.00 85.86 ? 529 SER B CA 529 SER B CA 1 ATOM 5425 C C . SER B 2 529 ? 15.870 5.168 10.303 1.00 85.86 ? 529 SER B C 529 SER B C 1 ATOM 5426 O O . SER B 2 529 ? 15.833 4.491 11.332 1.00 85.86 ? 529 SER B O 529 SER B O 1 ATOM 5427 C CB . SER B 2 529 ? 17.833 4.552 8.885 1.00 85.86 ? 529 SER B CB 529 SER B CB 1 ATOM 5428 O OG . SER B 2 529 ? 18.327 5.879 8.828 1.00 85.86 ? 529 SER B OG 529 SER B OG 1 ATOM 5429 N N . LYS B 2 530 ? 15.403 6.405 10.290 1.00 86.28 ? 530 LYS B N 530 LYS B N 1 ATOM 5430 C CA . LYS B 2 530 ? 15.060 7.103 11.526 1.00 86.28 ? 530 LYS B CA 530 LYS B CA 1 ATOM 5431 C C . LYS B 2 530 ? 13.620 6.812 11.940 1.00 86.28 ? 530 LYS B C 530 LYS B C 1 ATOM 5432 O O . LYS B 2 530 ? 13.324 6.686 13.130 1.00 86.28 ? 530 LYS B O 530 LYS B O 1 ATOM 5433 C CB . LYS B 2 530 ? 15.265 8.610 11.366 1.00 86.28 ? 530 LYS B CB 530 LYS B CB 1 ATOM 5434 C CG . LYS B 2 530 ? 16.721 9.023 11.208 1.00 86.28 ? 530 LYS B CG 530 LYS B CG 1 ATOM 5435 C CD . LYS B 2 530 ? 16.867 10.537 11.126 1.00 86.28 ? 530 LYS B CD 530 LYS B CD 1 ATOM 5436 C CE . LYS B 2 530 ? 18.316 10.949 10.902 1.00 86.28 ? 530 LYS B CE 530 LYS B CE 1 ATOM 5437 N NZ . LYS B 2 530 ? 18.453 12.427 10.740 1.00 86.28 ? 530 LYS B NZ 530 LYS B NZ 1 ATOM 5438 N N . THR B 2 531 ? 12.736 6.686 11.022 1.00 86.30 ? 531 THR B N 531 THR B N 1 ATOM 5439 C CA . THR B 2 531 ? 11.321 6.525 11.338 1.00 86.30 ? 531 THR B CA 531 THR B CA 1 ATOM 5440 C C . THR B 2 531 ? 10.868 5.092 11.076 1.00 86.30 ? 531 THR B C 531 THR B C 1 ATOM 5441 O O . THR B 2 531 ? 9.999 4.572 11.780 1.00 86.30 ? 531 THR B O 531 THR B O 1 ATOM 5442 C CB . THR B 2 531 ? 10.452 7.499 10.521 1.00 86.30 ? 531 THR B CB 531 THR B CB 1 ATOM 5443 O OG1 . THR B 2 531 ? 10.760 7.352 9.129 1.00 86.30 ? 531 THR B OG1 531 THR B OG1 1 ATOM 5444 C CG2 . THR B 2 531 ? 10.707 8.944 10.936 1.00 86.30 ? 531 THR B CG2 531 THR B CG2 1 ATOM 5445 N N . CYS B 2 532 ? 11.442 4.449 10.097 1.00 90.51 ? 532 CYS B N 532 CYS B N 1 ATOM 5446 C CA . CYS B 2 532 ? 10.997 3.121 9.690 1.00 90.51 ? 532 CYS B CA 532 CYS B CA 1 ATOM 5447 C C . CYS B 2 532 ? 12.122 2.102 9.827 1.00 90.51 ? 532 CYS B C 532 CYS B C 1 ATOM 5448 O O . CYS B 2 532 ? 12.575 1.534 8.831 1.00 90.51 ? 532 CYS B O 532 CYS B O 1 ATOM 5449 C CB . CYS B 2 532 ? 10.489 3.144 8.249 1.00 90.51 ? 532 CYS B CB 532 CYS B CB 1 ATOM 5450 S SG . CYS B 2 532 ? 9.074 4.236 7.992 1.00 90.51 ? 532 CYS B SG 532 CYS B SG 1 ATOM 5451 N N . GLN B 2 533 ? 12.572 1.842 11.055 1.00 90.69 ? 533 GLN B N 533 GLN B N 1 ATOM 5452 C CA . GLN B 2 533 ? 13.594 0.831 11.304 1.00 90.69 ? 533 GLN B CA 533 GLN B CA 1 ATOM 5453 C C . GLN B 2 533 ? 13.023 -0.576 11.157 1.00 90.69 ? 533 GLN B C 533 GLN B C 1 ATOM 5454 O O . GLN B 2 533 ? 11.871 -0.825 11.517 1.00 90.69 ? 533 GLN B O 533 GLN B O 1 ATOM 5455 C CB . GLN B 2 533 ? 14.198 1.010 12.698 1.00 90.69 ? 533 GLN B CB 533 GLN B CB 1 ATOM 5456 C CG . GLN B 2 533 ? 14.946 2.324 12.880 1.00 90.69 ? 533 GLN B CG 533 GLN B CG 1 ATOM 5457 C CD . GLN B 2 533 ? 15.520 2.484 14.275 1.00 90.69 ? 533 GLN B CD 533 GLN B CD 1 ATOM 5458 O OE1 . GLN B 2 533 ? 15.353 1.612 15.134 1.00 90.69 ? 533 GLN B OE1 533 GLN B OE1 1 ATOM 5459 N NE2 . GLN B 2 533 ? 16.200 3.601 14.513 1.00 90.69 ? 533 GLN B NE2 533 GLN B NE2 1 ATOM 5460 N N . PRO B 2 534 ? 13.804 -1.351 10.525 1.00 88.86 ? 534 PRO B N 534 PRO B N 1 ATOM 5461 C CA . PRO B 2 534 ? 13.296 -2.718 10.387 1.00 88.86 ? 534 PRO B CA 534 PRO B CA 1 ATOM 5462 C C . PRO B 2 534 ? 13.049 -3.394 11.734 1.00 88.86 ? 534 PRO B C 534 PRO B C 1 ATOM 5463 O O . PRO B 2 534 ? 13.758 -3.121 12.706 1.00 88.86 ? 534 PRO B O 534 PRO B O 1 ATOM 5464 C CB . PRO B 2 534 ? 14.409 -3.432 9.615 1.00 88.86 ? 534 PRO B CB 534 PRO B CB 1 ATOM 5465 C CG . PRO B 2 534 ? 15.653 -2.675 9.951 1.00 88.86 ? 534 PRO B CG 534 PRO B CG 1 ATOM 5466 C CD . PRO B 2 534 ? 15.293 -1.232 10.155 1.00 88.86 ? 534 PRO B CD 534 PRO B CD 1 ATOM 5467 N N . SER B 2 535 ? 12.022 -4.150 11.797 1.00 91.84 ? 535 SER B N 535 SER B N 1 ATOM 5468 C CA . SER B 2 535 ? 11.738 -4.945 12.988 1.00 91.84 ? 535 SER B CA 535 SER B CA 1 ATOM 5469 C C . SER B 2 535 ? 12.785 -6.035 13.188 1.00 91.84 ? 535 SER B C 535 SER B C 1 ATOM 5470 O O . SER B 2 535 ? 13.455 -6.442 12.237 1.00 91.84 ? 535 SER B O 535 SER B O 1 ATOM 5471 C CB . SER B 2 535 ? 10.347 -5.573 12.894 1.00 91.84 ? 535 SER B CB 535 SER B CB 1 ATOM 5472 O OG . SER B 2 535 ? 9.346 -4.572 12.834 1.00 91.84 ? 535 SER B OG 535 SER B OG 1 ATOM 5473 N N . TRP B 2 536 ? 13.033 -6.470 14.482 1.00 94.03 ? 536 TRP B N 536 TRP B N 1 ATOM 5474 C CA . TRP B 2 536 ? 13.985 -7.520 14.829 1.00 94.03 ? 536 TRP B CA 536 TRP B CA 1 ATOM 5475 C C . TRP B 2 536 ? 13.492 -8.882 14.350 1.00 94.03 ? 536 TRP B C 536 TRP B C 1 ATOM 5476 O O . TRP B 2 536 ? 12.601 -9.476 14.960 1.00 94.03 ? 536 TRP B O 536 TRP B O 1 ATOM 5477 C CB . TRP B 2 536 ? 14.223 -7.553 16.341 1.00 94.03 ? 536 TRP B CB 536 TRP B CB 1 ATOM 5478 C CG . TRP B 2 536 ? 15.340 -8.461 16.762 1.00 94.03 ? 536 TRP B CG 536 TRP B CG 1 ATOM 5479 C CD1 . TRP B 2 536 ? 16.452 -8.790 16.038 1.00 94.03 ? 536 TRP B CD1 536 TRP B CD1 1 ATOM 5480 C CD2 . TRP B 2 536 ? 15.449 -9.160 18.005 1.00 94.03 ? 536 TRP B CD2 536 TRP B CD2 1 ATOM 5481 N NE1 . TRP B 2 536 ? 17.247 -9.652 16.757 1.00 94.03 ? 536 TRP B NE1 536 TRP B NE1 1 ATOM 5482 C CE2 . TRP B 2 536 ? 16.655 -9.895 17.967 1.00 94.03 ? 536 TRP B CE2 536 TRP B CE2 1 ATOM 5483 C CE3 . TRP B 2 536 ? 14.644 -9.236 19.150 1.00 94.03 ? 536 TRP B CE3 536 TRP B CE3 1 ATOM 5484 C CZ2 . TRP B 2 536 ? 17.075 -10.697 19.031 1.00 94.03 ? 536 TRP B CZ2 536 TRP B CZ2 1 ATOM 5485 C CZ3 . TRP B 2 536 ? 15.064 -10.035 20.208 1.00 94.03 ? 536 TRP B CZ3 536 TRP B CZ3 1 ATOM 5486 C CH2 . TRP B 2 536 ? 16.268 -10.753 20.139 1.00 94.03 ? 536 TRP B CH2 536 TRP B CH2 1 ATOM 5487 N N . ILE B 2 537 ? 14.038 -9.313 13.158 1.00 94.80 ? 537 ILE B N 537 ILE B N 1 ATOM 5488 C CA . ILE B 2 537 ? 13.606 -10.574 12.566 1.00 94.80 ? 537 ILE B CA 537 ILE B CA 1 ATOM 5489 C C . ILE B 2 537 ? 14.825 -11.392 12.147 1.00 94.80 ? 537 ILE B C 537 ILE B C 1 ATOM 5490 O O . ILE B 2 537 ? 15.931 -10.857 12.035 1.00 94.80 ? 537 ILE B O 537 ILE B O 1 ATOM 5491 C CB . ILE B 2 537 ? 12.675 -10.340 11.354 1.00 94.80 ? 537 ILE B CB 537 ILE B CB 1 ATOM 5492 C CG1 . ILE B 2 537 ? 13.409 -9.554 10.262 1.00 94.80 ? 537 ILE B CG1 537 ILE B CG1 1 ATOM 5493 C CG2 . ILE B 2 537 ? 11.398 -9.616 11.787 1.00 94.80 ? 537 ILE B CG2 537 ILE B CG2 1 ATOM 5494 C CD1 . ILE B 2 537 ? 13.502 -10.284 8.929 1.00 94.80 ? 537 ILE B CD1 537 ILE B CD1 1 ATOM 5495 N N . HIS B 2 538 ? 14.606 -12.681 12.033 1.00 94.43 ? 538 HIS B N 538 HIS B N 1 ATOM 5496 C CA . HIS B 2 538 ? 15.610 -13.592 11.497 1.00 94.43 ? 538 HIS B CA 538 HIS B CA 1 ATOM 5497 C C . HIS B 2 538 ? 15.000 -14.540 10.469 1.00 94.43 ? 538 HIS B C 538 HIS B C 1 ATOM 5498 O O . HIS B 2 538 ? 14.132 -15.350 10.804 1.00 94.43 ? 538 HIS B O 538 HIS B O 1 ATOM 5499 C CB . HIS B 2 538 ? 16.265 -14.392 12.625 1.00 94.43 ? 538 HIS B CB 538 HIS B CB 1 ATOM 5500 C CG . HIS B 2 538 ? 17.357 -15.302 12.159 1.00 94.43 ? 538 HIS B CG 538 HIS B CG 1 ATOM 5501 N ND1 . HIS B 2 538 ? 18.599 -14.841 11.782 1.00 94.43 ? 538 HIS B ND1 538 HIS B ND1 1 ATOM 5502 C CD2 . HIS B 2 538 ? 17.390 -16.647 12.013 1.00 94.43 ? 538 HIS B CD2 538 HIS B CD2 1 ATOM 5503 C CE1 . HIS B 2 538 ? 19.352 -15.867 11.423 1.00 94.43 ? 538 HIS B CE1 538 HIS B CE1 1 ATOM 5504 N NE2 . HIS B 2 538 ? 18.642 -16.975 11.554 1.00 94.43 ? 538 HIS B NE2 538 HIS B NE2 1 ATOM 5505 N N . SER B 2 539 ? 15.455 -14.327 9.192 1.00 93.66 ? 539 SER B N 539 SER B N 1 ATOM 5506 C CA . SER B 2 539 ? 15.034 -15.216 8.114 1.00 93.66 ? 539 SER B CA 539 SER B CA 1 ATOM 5507 C C . SER B 2 539 ? 16.046 -16.335 7.892 1.00 93.66 ? 539 SER B C 539 SER B C 1 ATOM 5508 O O . SER B 2 539 ? 17.254 -16.120 8.014 1.00 93.66 ? 539 SER B O 539 SER B O 1 ATOM 5509 C CB . SER B 2 539 ? 14.839 -14.430 6.816 1.00 93.66 ? 539 SER B CB 539 SER B CB 1 ATOM 5510 O OG . SER B 2 539 ? 14.576 -15.305 5.733 1.00 93.66 ? 539 SER B OG 539 SER B OG 1 ATOM 5511 N N . GLN B 2 540 ? 15.561 -17.525 7.528 1.00 91.87 ? 540 GLN B N 540 GLN B N 1 ATOM 5512 C CA . GLN B 2 540 ? 16.435 -18.660 7.249 1.00 91.87 ? 540 GLN B CA 540 GLN B CA 1 ATOM 5513 C C . GLN B 2 540 ? 17.101 -18.518 5.883 1.00 91.87 ? 540 GLN B C 540 GLN B C 1 ATOM 5514 O O . GLN B 2 540 ? 18.062 -19.228 5.579 1.00 91.87 ? 540 GLN B O 540 GLN B O 1 ATOM 5515 C CB . GLN B 2 540 ? 15.651 -19.971 7.317 1.00 91.87 ? 540 GLN B CB 540 GLN B CB 1 ATOM 5516 C CG . GLN B 2 540 ? 15.101 -20.288 8.701 1.00 91.87 ? 540 GLN B CG 540 GLN B CG 1 ATOM 5517 C CD . GLN B 2 540 ? 14.218 -21.522 8.714 1.00 91.87 ? 540 GLN B CD 540 GLN B CD 1 ATOM 5518 O OE1 . GLN B 2 540 ? 14.091 -22.221 7.703 1.00 91.87 ? 540 GLN B OE1 540 GLN B OE1 1 ATOM 5519 N NE2 . GLN B 2 540 ? 13.601 -21.798 9.858 1.00 91.87 ? 540 GLN B NE2 540 GLN B NE2 1 ATOM 5520 N N . HIS B 2 541 ? 16.630 -17.497 5.120 1.00 91.65 ? 541 HIS B N 541 HIS B N 1 ATOM 5521 C CA . HIS B 2 541 ? 17.102 -17.358 3.746 1.00 91.65 ? 541 HIS B CA 541 HIS B CA 1 ATOM 5522 C C . HIS B 2 541 ? 18.083 -16.198 3.615 1.00 91.65 ? 541 HIS B C 541 HIS B C 1 ATOM 5523 O O . HIS B 2 541 ? 18.081 -15.281 4.440 1.00 91.65 ? 541 HIS B O 541 HIS B O 1 ATOM 5524 C CB . HIS B 2 541 ? 15.923 -17.159 2.792 1.00 91.65 ? 541 HIS B CB 541 HIS B CB 1 ATOM 5525 C CG . HIS B 2 541 ? 14.922 -18.270 2.835 1.00 91.65 ? 541 HIS B CG 541 HIS B CG 1 ATOM 5526 N ND1 . HIS B 2 541 ? 15.171 -19.516 2.301 1.00 91.65 ? 541 HIS B ND1 541 HIS B ND1 1 ATOM 5527 C CD2 . HIS B 2 541 ? 13.672 -18.321 3.350 1.00 91.65 ? 541 HIS B CD2 541 HIS B CD2 1 ATOM 5528 C CE1 . HIS B 2 541 ? 14.113 -20.287 2.487 1.00 91.65 ? 541 HIS B CE1 541 HIS B CE1 1 ATOM 5529 N NE2 . HIS B 2 541 ? 13.189 -19.586 3.121 1.00 91.65 ? 541 HIS B NE2 541 HIS B NE2 1 ATOM 5530 N N . GLU B 2 542 ? 18.937 -16.344 2.677 1.00 90.93 ? 542 GLU B N 542 GLU B N 1 ATOM 5531 C CA . GLU B 2 542 ? 19.902 -15.294 2.364 1.00 90.93 ? 542 GLU B CA 542 GLU B CA 1 ATOM 5532 C C . GLU B 2 542 ? 20.069 -15.129 0.857 1.00 90.93 ? 542 GLU B C 542 GLU B C 1 ATOM 5533 O O . GLU B 2 542 ? 19.759 -16.042 0.089 1.00 90.93 ? 542 GLU B O 542 GLU B O 1 ATOM 5534 C CB . GLU B 2 542 ? 21.254 -15.596 3.014 1.00 90.93 ? 542 GLU B CB 542 GLU B CB 1 ATOM 5535 C CG . GLU B 2 542 ? 21.962 -16.809 2.427 1.00 90.93 ? 542 GLU B CG 542 GLU B CG 1 ATOM 5536 C CD . GLU B 2 542 ? 23.315 -17.081 3.064 1.00 90.93 ? 542 GLU B CD 542 GLU B CD 1 ATOM 5537 O OE1 . GLU B 2 542 ? 24.003 -18.039 2.643 1.00 90.93 ? 542 GLU B OE1 542 GLU B OE1 1 ATOM 5538 O OE2 . GLU B 2 542 ? 23.690 -16.332 3.993 1.00 90.93 ? 542 GLU B OE2 542 GLU B OE2 1 ATOM 5539 N N . LEU B 2 543 ? 20.466 -13.953 0.451 1.00 89.74 ? 543 LEU B N 543 LEU B N 1 ATOM 5540 C CA . LEU B 2 543 ? 20.695 -13.680 -0.964 1.00 89.74 ? 543 LEU B CA 543 LEU B CA 1 ATOM 5541 C C . LEU B 2 543 ? 21.937 -14.409 -1.465 1.00 89.74 ? 543 LEU B C 543 LEU B C 1 ATOM 5542 O O . LEU B 2 543 ? 22.968 -14.425 -0.788 1.00 89.74 ? 543 LEU B O 543 LEU B O 1 ATOM 5543 C CB . LEU B 2 543 ? 20.842 -12.175 -1.203 1.00 89.74 ? 543 LEU B CB 543 LEU B CB 1 ATOM 5544 C CG . LEU B 2 543 ? 19.591 -11.326 -0.972 1.00 89.74 ? 543 LEU B CG 543 LEU B CG 1 ATOM 5545 C CD1 . LEU B 2 543 ? 19.951 -9.844 -0.956 1.00 89.74 ? 543 LEU B CD1 543 LEU B CD1 1 ATOM 5546 C CD2 . LEU B 2 543 ? 18.544 -11.615 -2.042 1.00 89.74 ? 543 LEU B CD2 543 LEU B CD2 1 ATOM 5547 N N . ASN B 2 544 ? 21.854 -15.096 -2.603 1.00 88.33 ? 544 ASN B N 544 ASN B N 1 ATOM 5548 C CA . ASN B 2 544 ? 22.966 -15.810 -3.220 1.00 88.33 ? 544 ASN B CA 544 ASN B CA 1 ATOM 5549 C C . ASN B 2 544 ? 23.986 -14.847 -3.822 1.00 88.33 ? 544 ASN B C 544 ASN B C 1 ATOM 5550 O O . ASN B 2 544 ? 23.700 -14.172 -4.812 1.00 88.33 ? 544 ASN B O 544 ASN B O 1 ATOM 5551 C CB . ASN B 2 544 ? 22.456 -16.778 -4.289 1.00 88.33 ? 544 ASN B CB 544 ASN B CB 1 ATOM 5552 C CG . ASN B 2 544 ? 23.561 -17.632 -4.880 1.00 88.33 ? 544 ASN B CG 544 ASN B CG 1 ATOM 5553 O OD1 . ASN B 2 544 ? 24.736 -17.469 -4.542 1.00 88.33 ? 544 ASN B OD1 544 ASN B OD1 1 ATOM 5554 N ND2 . ASN B 2 544 ? 23.192 -18.548 -5.767 1.00 88.33 ? 544 ASN B ND2 544 ASN B ND2 1 ATOM 5555 N N . PRO B 2 545 ? 25.154 -14.823 -3.262 1.00 86.96 ? 545 PRO B N 545 PRO B N 1 ATOM 5556 C CA . PRO B 2 545 ? 26.170 -13.877 -3.729 1.00 86.96 ? 545 PRO B CA 545 PRO B CA 1 ATOM 5557 C C . PRO B 2 545 ? 26.693 -14.214 -5.123 1.00 86.96 ? 545 PRO B C 545 PRO B C 1 ATOM 5558 O O . PRO B 2 545 ? 27.312 -13.369 -5.775 1.00 86.96 ? 545 PRO B O 545 PRO B O 1 ATOM 5559 C CB . PRO B 2 545 ? 27.280 -14.007 -2.683 1.00 86.96 ? 545 PRO B CB 545 PRO B CB 1 ATOM 5560 C CG . PRO B 2 545 ? 27.094 -15.369 -2.096 1.00 86.96 ? 545 PRO B CG 545 PRO B CG 1 ATOM 5561 C CD . PRO B 2 545 ? 25.633 -15.714 -2.145 1.00 86.96 ? 545 PRO B CD 545 PRO B CD 1 ATOM 5562 N N . GLN B 2 546 ? 26.402 -15.377 -5.634 1.00 87.80 ? 546 GLN B N 546 GLN B N 1 ATOM 5563 C CA . GLN B 2 546 ? 26.905 -15.800 -6.937 1.00 87.80 ? 546 GLN B CA 546 GLN B CA 1 ATOM 5564 C C . GLN B 2 546 ? 26.030 -15.263 -8.065 1.00 87.80 ? 546 GLN B C 546 GLN B C 1 ATOM 5565 O O . GLN B 2 546 ? 26.458 -15.213 -9.220 1.00 87.80 ? 546 GLN B O 546 GLN B O 1 ATOM 5566 C CB . GLN B 2 546 ? 26.984 -17.325 -7.013 1.00 87.80 ? 546 GLN B CB 546 GLN B CB 1 ATOM 5567 C CG . GLN B 2 546 ? 27.936 -17.944 -5.998 1.00 87.80 ? 546 GLN B CG 546 GLN B CG 1 ATOM 5568 C CD . GLN B 2 546 ? 29.346 -17.393 -6.104 1.00 87.80 ? 546 GLN B CD 546 GLN B CD 1 ATOM 5569 O OE1 . GLN B 2 546 ? 29.777 -16.958 -7.177 1.00 87.80 ? 546 GLN B OE1 546 GLN B OE1 1 ATOM 5570 N NE2 . GLN B 2 546 ? 30.074 -17.408 -4.993 1.00 87.80 ? 546 GLN B NE2 546 GLN B NE2 1 ATOM 5571 N N . ASP B 2 547 ? 24.858 -14.914 -7.769 1.00 89.23 ? 547 ASP B N 547 ASP B N 1 ATOM 5572 C CA . ASP B 2 547 ? 23.945 -14.314 -8.737 1.00 89.23 ? 547 ASP B CA 547 ASP B CA 1 ATOM 5573 C C . ASP B 2 547 ? 24.384 -12.897 -9.101 1.00 89.23 ? 547 ASP B C 547 ASP B C 1 ATOM 5574 O O . ASP B 2 547 ? 24.674 -12.086 -8.219 1.00 89.23 ? 547 ASP B O 547 ASP B O 1 ATOM 5575 C CB . ASP B 2 547 ? 22.516 -14.298 -8.191 1.00 89.23 ? 547 ASP B CB 547 ASP B CB 1 ATOM 5576 C CG . ASP B 2 547 ? 21.481 -13.959 -9.248 1.00 89.23 ? 547 ASP B CG 547 ASP B CG 1 ATOM 5577 O OD1 . ASP B 2 547 ? 21.853 -13.439 -10.322 1.00 89.23 ? 547 ASP B OD1 547 ASP B OD1 1 ATOM 5578 O OD2 . ASP B 2 547 ? 20.281 -14.211 -9.004 1.00 89.23 ? 547 ASP B OD2 547 ASP B OD2 1 ATOM 5579 N N . SER B 2 548 ? 24.510 -12.595 -10.423 1.00 91.17 ? 548 SER B N 548 SER B N 1 ATOM 5580 C CA . SER B 2 548 ? 24.998 -11.309 -10.909 1.00 91.17 ? 548 SER B CA 548 SER B CA 1 ATOM 5581 C C . SER B 2 548 ? 24.126 -10.162 -10.408 1.00 91.17 ? 548 SER B C 548 SER B C 1 ATOM 5582 O O . SER B 2 548 ? 24.639 -9.112 -10.015 1.00 91.17 ? 548 SER B O 548 SER B O 1 ATOM 5583 C CB . SER B 2 548 ? 25.044 -11.295 -12.437 1.00 91.17 ? 548 SER B CB 548 SER B CB 1 ATOM 5584 O OG . SER B 2 548 ? 23.742 -11.424 -12.981 1.00 91.17 ? 548 SER B OG 548 SER B OG 1 ATOM 5585 N N . ILE B 2 549 ? 22.822 -10.356 -10.413 1.00 93.12 ? 549 ILE B N 549 ILE B N 1 ATOM 5586 C CA . ILE B 2 549 ? 21.892 -9.321 -9.975 1.00 93.12 ? 549 ILE B CA 549 ILE B CA 1 ATOM 5587 C C . ILE B 2 549 ? 22.078 -9.059 -8.483 1.00 93.12 ? 549 ILE B C 549 ILE B C 1 ATOM 5588 O O . ILE B 2 549 ? 22.088 -7.906 -8.045 1.00 93.12 ? 549 ILE B O 549 ILE B O 1 ATOM 5589 C CB . ILE B 2 549 ? 20.428 -9.715 -10.273 1.00 93.12 ? 549 ILE B CB 549 ILE B CB 1 ATOM 5590 C CG1 . ILE B 2 549 ? 20.222 -9.907 -11.780 1.00 93.12 ? 549 ILE B CG1 549 ILE B CG1 1 ATOM 5591 C CG2 . ILE B 2 549 ? 19.463 -8.663 -9.718 1.00 93.12 ? 549 ILE B CG2 549 ILE B CG2 1 ATOM 5592 C CD1 . ILE B 2 549 ? 20.433 -8.642 -12.600 1.00 93.12 ? 549 ILE B CD1 549 ILE B CD1 1 ATOM 5593 N N . VAL B 2 550 ? 22.271 -10.115 -7.690 1.00 92.37 ? 550 VAL B N 550 VAL B N 1 ATOM 5594 C CA . VAL B 2 550 ? 22.438 -10.003 -6.245 1.00 92.37 ? 550 VAL B CA 550 VAL B CA 1 ATOM 5595 C C . VAL B 2 550 ? 23.743 -9.274 -5.931 1.00 92.37 ? 550 VAL B C 550 VAL B C 1 ATOM 5596 O O . VAL B 2 550 ? 23.803 -8.469 -4.998 1.00 92.37 ? 550 VAL B O 550 VAL B O 1 ATOM 5597 C CB . VAL B 2 550 ? 22.425 -11.389 -5.562 1.00 92.37 ? 550 VAL B CB 550 VAL B CB 1 ATOM 5598 C CG1 . VAL B 2 550 ? 22.767 -11.264 -4.079 1.00 92.37 ? 550 VAL B CG1 550 VAL B CG1 1 ATOM 5599 C CG2 . VAL B 2 550 ? 21.065 -12.060 -5.746 1.00 92.37 ? 550 VAL B CG2 550 VAL B CG2 1 ATOM 5600 N N . GLN B 2 551 ? 24.786 -9.539 -6.709 1.00 92.90 ? 551 GLN B N 551 GLN B N 1 ATOM 5601 C CA . GLN B 2 551 ? 26.040 -8.809 -6.552 1.00 92.90 ? 551 GLN B CA 551 GLN B CA 1 ATOM 5602 C C . GLN B 2 551 ? 25.829 -7.308 -6.729 1.00 92.90 ? 551 GLN B C 551 GLN B C 1 ATOM 5603 O O . GLN B 2 551 ? 26.400 -6.504 -5.989 1.00 92.90 ? 551 GLN B O 551 GLN B O 1 ATOM 5604 C CB . GLN B 2 551 ? 27.084 -9.313 -7.550 1.00 92.90 ? 551 GLN B CB 551 GLN B CB 1 ATOM 5605 C CG . GLN B 2 551 ? 27.602 -10.712 -7.243 1.00 92.90 ? 551 GLN B CG 551 GLN B CG 1 ATOM 5606 C CD . GLN B 2 551 ? 28.581 -11.217 -8.286 1.00 92.90 ? 551 GLN B CD 551 GLN B CD 1 ATOM 5607 O OE1 . GLN B 2 551 ? 28.793 -10.575 -9.320 1.00 92.90 ? 551 GLN B OE1 551 GLN B OE1 1 ATOM 5608 N NE2 . GLN B 2 551 ? 29.183 -12.372 -8.024 1.00 92.90 ? 551 GLN B NE2 551 GLN B NE2 1 ATOM 5609 N N . GLY B 2 552 ? 25.047 -7.015 -7.701 1.00 93.30 ? 552 GLY B N 552 GLY B N 1 ATOM 5610 C CA . GLY B 2 552 ? 24.697 -5.619 -7.911 1.00 93.30 ? 552 GLY B CA 552 GLY B CA 1 ATOM 5611 C C . GLY B 2 552 ? 23.945 -5.010 -6.742 1.00 93.30 ? 552 GLY B C 552 GLY B C 1 ATOM 5612 O O . GLY B 2 552 ? 24.185 -3.858 -6.376 1.00 93.30 ? 552 GLY B O 552 GLY B O 1 ATOM 5613 N N . ILE B 2 553 ? 23.097 -5.759 -6.127 1.00 94.18 ? 553 ILE B N 553 ILE B N 1 ATOM 5614 C CA . ILE B 2 553 ? 22.315 -5.318 -4.977 1.00 94.18 ? 553 ILE B CA 553 ILE B CA 1 ATOM 5615 C C . ILE B 2 553 ? 23.248 -4.983 -3.816 1.00 94.18 ? 553 ILE B C 553 ILE B C 1 ATOM 5616 O O . ILE B 2 553 ? 23.088 -3.949 -3.162 1.00 94.18 ? 553 ILE B O 553 ILE B O 1 ATOM 5617 C CB . ILE B 2 553 ? 21.288 -6.390 -4.547 1.00 94.18 ? 553 ILE B CB 553 ILE B CB 1 ATOM 5618 C CG1 . ILE B 2 553 ? 20.227 -6.581 -5.636 1.00 94.18 ? 553 ILE B CG1 553 ILE B CG1 1 ATOM 5619 C CG2 . ILE B 2 553 ? 20.641 -6.013 -3.211 1.00 94.18 ? 553 ILE B CG2 553 ILE B CG2 1 ATOM 5620 C CD1 . ILE B 2 553 ? 19.278 -7.744 -5.380 1.00 94.18 ? 553 ILE B CD1 553 ILE B CD1 1 ATOM 5621 N N . PHE B 2 554 ? 24.193 -5.827 -3.554 1.00 94.43 ? 554 PHE B N 554 PHE B N 1 ATOM 5622 C CA . PHE B 2 554 ? 25.157 -5.596 -2.485 1.00 94.43 ? 554 PHE B CA 554 PHE B CA 1 ATOM 5623 C C . PHE B 2 554 ? 25.992 -4.353 -2.768 1.00 94.43 ? 554 PHE B C 554 PHE B C 1 ATOM 5624 O O . PHE B 2 554 ? 26.298 -3.583 -1.856 1.00 94.43 ? 554 PHE B O 554 PHE B O 1 ATOM 5625 C CB . PHE B 2 554 ? 26.071 -6.813 -2.311 1.00 94.43 ? 554 PHE B CB 554 PHE B CB 1 ATOM 5626 C CG . PHE B 2 554 ? 25.413 -7.971 -1.610 1.00 94.43 ? 554 PHE B CG 554 PHE B CG 1 ATOM 5627 C CD1 . PHE B 2 554 ? 24.789 -7.793 -0.381 1.00 94.43 ? 554 PHE B CD1 554 PHE B CD1 1 ATOM 5628 C CD2 . PHE B 2 554 ? 25.419 -9.237 -2.180 1.00 94.43 ? 554 PHE B CD2 554 PHE B CD2 1 ATOM 5629 C CE1 . PHE B 2 554 ? 24.179 -8.863 0.270 1.00 94.43 ? 554 PHE B CE1 554 PHE B CE1 1 ATOM 5630 C CE2 . PHE B 2 554 ? 24.812 -10.311 -1.535 1.00 94.43 ? 554 PHE B CE2 554 PHE B CE2 1 ATOM 5631 C CZ . PHE B 2 554 ? 24.193 -10.122 -0.310 1.00 94.43 ? 554 PHE B CZ 554 PHE B CZ 1 ATOM 5632 N N . GLN B 2 555 ? 26.368 -4.151 -4.029 1.00 93.78 ? 555 GLN B N 555 GLN B N 1 ATOM 5633 C CA . GLN B 2 555 ? 27.122 -2.965 -4.423 1.00 93.78 ? 555 GLN B CA 555 GLN B CA 1 ATOM 5634 C C . GLN B 2 555 ? 26.300 -1.696 -4.214 1.00 93.78 ? 555 GLN B C 555 GLN B C 1 ATOM 5635 O O . GLN B 2 555 ? 26.828 -0.674 -3.772 1.00 93.78 ? 555 GLN B O 555 GLN B O 1 ATOM 5636 C CB . GLN B 2 555 ? 27.563 -3.070 -5.884 1.00 93.78 ? 555 GLN B CB 555 GLN B CB 1 ATOM 5637 C CG . GLN B 2 555 ? 28.642 -4.116 -6.127 1.00 93.78 ? 555 GLN B CG 555 GLN B CG 1 ATOM 5638 C CD . GLN B 2 555 ? 29.036 -4.225 -7.588 1.00 93.78 ? 555 GLN B CD 555 GLN B CD 1 ATOM 5639 O OE1 . GLN B 2 555 ? 28.668 -3.379 -8.408 1.00 93.78 ? 555 GLN B OE1 555 GLN B OE1 1 ATOM 5640 N NE2 . GLN B 2 555 ? 29.786 -5.269 -7.923 1.00 93.78 ? 555 GLN B NE2 555 GLN B NE2 1 ATOM 5641 N N . LEU B 2 556 ? 25.027 -1.778 -4.556 1.00 93.95 ? 556 LEU B N 556 LEU B N 1 ATOM 5642 C CA . LEU B 2 556 ? 24.139 -0.640 -4.346 1.00 93.95 ? 556 LEU B CA 556 LEU B CA 1 ATOM 5643 C C . LEU B 2 556 ? 24.030 -0.300 -2.864 1.00 93.95 ? 556 LEU B C 556 LEU B C 1 ATOM 5644 O O . LEU B 2 556 ? 24.014 0.875 -2.491 1.00 93.95 ? 556 LEU B O 556 LEU B O 1 ATOM 5645 C CB . LEU B 2 556 ? 22.749 -0.932 -4.918 1.00 93.95 ? 556 LEU B CB 556 LEU B CB 1 ATOM 5646 C CG . LEU B 2 556 ? 22.612 -0.855 -6.440 1.00 93.95 ? 556 LEU B CG 556 LEU B CG 1 ATOM 5647 C CD1 . LEU B 2 556 ? 21.227 -1.323 -6.872 1.00 93.95 ? 556 LEU B CD1 556 LEU B CD1 1 ATOM 5648 C CD2 . LEU B 2 556 ? 22.879 0.565 -6.929 1.00 93.95 ? 556 LEU B CD2 556 LEU B CD2 1 ATOM 5649 N N . ALA B 2 557 ? 23.940 -1.297 -2.087 1.00 92.91 ? 557 ALA B N 557 ALA B N 1 ATOM 5650 C CA . ALA B 2 557 ? 23.859 -1.103 -0.641 1.00 92.91 ? 557 ALA B CA 557 ALA B CA 1 ATOM 5651 C C . ALA B 2 557 ? 25.097 -0.385 -0.113 1.00 92.91 ? 557 ALA B C 557 ALA B C 1 ATOM 5652 O O . ALA B 2 557 ? 24.993 0.504 0.735 1.00 92.91 ? 557 ALA B O 557 ALA B O 1 ATOM 5653 C CB . ALA B 2 557 ? 23.683 -2.444 0.067 1.00 92.91 ? 557 ALA B CB 557 ALA B CB 1 ATOM 5654 N N . THR B 2 558 ? 26.256 -0.774 -0.601 1.00 93.85 ? 558 THR B N 558 THR B N 1 ATOM 5655 C CA . THR B 2 558 ? 27.510 -0.147 -0.197 1.00 93.85 ? 558 THR B CA 558 THR B CA 1 ATOM 5656 C C . THR B 2 558 ? 27.555 1.311 -0.645 1.00 93.85 ? 558 THR B C 558 THR B C 1 ATOM 5657 O O . THR B 2 558 ? 28.017 2.180 0.097 1.00 93.85 ? 558 THR B O 558 THR B O 1 ATOM 5658 C CB . THR B 2 558 ? 28.723 -0.902 -0.772 1.00 93.85 ? 558 THR B CB 558 THR B CB 1 ATOM 5659 O OG1 . THR B 2 558 ? 28.656 -2.276 -0.373 1.00 93.85 ? 558 THR B OG1 558 THR B OG1 1 ATOM 5660 C CG2 . THR B 2 558 ? 30.032 -0.302 -0.270 1.00 93.85 ? 558 THR B CG2 558 THR B CG2 1 ATOM 5661 N N . LEU B 2 559 ? 27.022 1.557 -1.827 1.00 93.43 ? 559 LEU B N 559 LEU B N 1 ATOM 5662 C CA . LEU B 2 559 ? 27.001 2.909 -2.375 1.00 93.43 ? 559 LEU B CA 559 LEU B CA 1 ATOM 5663 C C . LEU B 2 559 ? 26.055 3.803 -1.581 1.00 93.43 ? 559 LEU B C 559 LEU B C 1 ATOM 5664 O O . LEU B 2 559 ? 26.312 4.998 -1.420 1.00 93.43 ? 559 LEU B O 559 LEU B O 1 ATOM 5665 C CB . LEU B 2 559 ? 26.582 2.883 -3.848 1.00 93.43 ? 559 LEU B CB 559 LEU B CB 1 ATOM 5666 C CG . LEU B 2 559 ? 27.626 2.368 -4.841 1.00 93.43 ? 559 LEU B CG 559 LEU B CG 1 ATOM 5667 C CD1 . LEU B 2 559 ? 27.019 2.255 -6.235 1.00 93.43 ? 559 LEU B CD1 559 LEU B CD1 1 ATOM 5668 C CD2 . LEU B 2 559 ? 28.847 3.281 -4.855 1.00 93.43 ? 559 LEU B CD2 559 LEU B CD2 1 ATOM 5669 N N . ALA B 2 560 ? 24.995 3.261 -1.133 1.00 91.93 ? 560 ALA B N 560 ALA B N 1 ATOM 5670 C CA . ALA B 2 560 ? 24.004 4.014 -0.369 1.00 91.93 ? 560 ALA B CA 560 ALA B CA 1 ATOM 5671 C C . ALA B 2 560 ? 24.568 4.454 0.979 1.00 91.93 ? 560 ALA B C 560 ALA B C 1 ATOM 5672 O O . ALA B 2 560 ? 24.206 5.515 1.494 1.00 91.93 ? 560 ALA B O 560 ALA B O 1 ATOM 5673 C CB . ALA B 2 560 ? 22.742 3.178 -0.167 1.00 91.93 ? 560 ALA B CB 560 ALA B CB 1 ATOM 5674 N N . LYS B 2 561 ? 25.480 3.720 1.543 1.00 89.52 ? 561 LYS B N 561 LYS B N 1 ATOM 5675 C CA . LYS B 2 561 ? 26.062 3.999 2.852 1.00 89.52 ? 561 LYS B CA 561 LYS B CA 1 ATOM 5676 C C . LYS B 2 561 ? 27.226 4.979 2.739 1.00 89.52 ? 561 LYS B C 561 LYS B C 1 ATOM 5677 O O . LYS B 2 561 ? 27.560 5.669 3.704 1.00 89.52 ? 561 LYS B O 561 LYS B O 1 ATOM 5678 C CB . LYS B 2 561 ? 26.529 2.705 3.520 1.00 89.52 ? 561 LYS B CB 561 LYS B CB 1 ATOM 5679 C CG . LYS B 2 561 ? 25.395 1.785 3.947 1.00 89.52 ? 561 LYS B CG 561 LYS B CG 1 ATOM 5680 C CD . LYS B 2 561 ? 25.922 0.522 4.617 1.00 89.52 ? 561 LYS B CD 561 LYS B CD 1 ATOM 5681 C CE . LYS B 2 561 ? 24.791 -0.423 4.998 1.00 89.52 ? 561 LYS B CE 561 LYS B CE 1 ATOM 5682 N NZ . LYS B 2 561 ? 25.305 -1.676 5.628 1.00 89.52 ? 561 LYS B NZ 561 LYS B NZ 1 ATOM 5683 N N . ASP B 2 562 ? 27.770 5.022 1.562 1.00 88.94 ? 562 ASP B N 562 ASP B N 1 ATOM 5684 C CA . ASP B 2 562 ? 28.929 5.878 1.329 1.00 88.94 ? 562 ASP B CA 562 ASP B CA 1 ATOM 5685 C C . ASP B 2 562 ? 28.506 7.331 1.121 1.00 88.94 ? 562 ASP B C 562 ASP B C 1 ATOM 5686 O O . ASP B 2 562 ? 27.920 7.670 0.090 1.00 88.94 ? 562 ASP B O 562 ASP B O 1 ATOM 5687 C CB . ASP B 2 562 ? 29.728 5.384 0.122 1.00 88.94 ? 562 ASP B CB 562 ASP B CB 1 ATOM 5688 C CG . ASP B 2 562 ? 31.079 6.064 -0.014 1.00 88.94 ? 562 ASP B CG 562 ASP B CG 1 ATOM 5689 O OD1 . ASP B 2 562 ? 31.344 7.045 0.713 1.00 88.94 ? 562 ASP B OD1 562 ASP B OD1 1 ATOM 5690 O OD2 . ASP B 2 562 ? 31.885 5.616 -0.858 1.00 88.94 ? 562 ASP B OD2 562 ASP B OD2 1 ATOM 5691 N N . LYS B 2 563 ? 28.771 8.299 2.043 1.00 84.64 ? 563 LYS B N 563 LYS B N 1 ATOM 5692 C CA . LYS B 2 563 ? 28.349 9.696 2.040 1.00 84.64 ? 563 LYS B CA 563 LYS B CA 1 ATOM 5693 C C . LYS B 2 563 ? 29.239 10.537 1.130 1.00 84.64 ? 563 LYS B C 563 LYS B C 1 ATOM 5694 O O . LYS B 2 563 ? 28.775 11.499 0.515 1.00 84.64 ? 563 LYS B O 563 LYS B O 1 ATOM 5695 C CB . LYS B 2 563 ? 28.365 10.265 3.460 1.00 84.64 ? 563 LYS B CB 563 LYS B CB 1 ATOM 5696 C CG . LYS B 2 563 ? 27.285 9.695 4.367 1.00 84.64 ? 563 LYS B CG 563 LYS B CG 1 ATOM 5697 C CD . LYS B 2 563 ? 27.288 10.371 5.732 1.00 84.64 ? 563 LYS B CD 563 LYS B CD 1 ATOM 5698 C CE . LYS B 2 563 ? 26.230 9.777 6.653 1.00 84.64 ? 563 LYS B CE 563 LYS B CE 1 ATOM 5699 N NZ . LYS B 2 563 ? 26.225 10.441 7.991 1.00 84.64 ? 563 LYS B NZ 563 LYS B NZ 1 ATOM 5700 N N . ARG B 2 564 ? 30.481 10.136 0.981 1.00 84.07 ? 564 ARG B N 564 ARG B N 1 ATOM 5701 C CA . ARG B 2 564 ? 31.448 10.955 0.256 1.00 84.07 ? 564 ARG B CA 564 ARG B CA 1 ATOM 5702 C C . ARG B 2 564 ? 31.392 10.672 -1.241 1.00 84.07 ? 564 ARG B C 564 ARG B C 1 ATOM 5703 O O . ARG B 2 564 ? 31.331 11.599 -2.052 1.00 84.07 ? 564 ARG B O 564 ARG B O 1 ATOM 5704 C CB . ARG B 2 564 ? 32.863 10.710 0.783 1.00 84.07 ? 564 ARG B CB 564 ARG B CB 1 ATOM 5705 C CG . ARG B 2 564 ? 33.873 11.760 0.347 1.00 84.07 ? 564 ARG B CG 564 ARG B CG 1 ATOM 5706 C CD . ARG B 2 564 ? 35.153 11.686 1.168 1.00 84.07 ? 564 ARG B CD 564 ARG B CD 1 ATOM 5707 N NE . ARG B 2 564 ? 36.112 12.710 0.764 1.00 84.07 ? 564 ARG B NE 564 ARG B NE 1 ATOM 5708 C CZ . ARG B 2 564 ? 37.433 12.596 0.871 1.00 84.07 ? 564 ARG B CZ 564 ARG B CZ 1 ATOM 5709 N NH1 . ARG B 2 564 ? 37.980 11.495 1.375 1.00 84.07 ? 564 ARG B NH1 564 ARG B NH1 1 ATOM 5710 N NH2 . ARG B 2 564 ? 38.214 13.589 0.473 1.00 84.07 ? 564 ARG B NH2 564 ARG B NH2 1 ATOM 5711 N N . PHE B 2 565 ? 31.387 9.372 -1.675 1.00 84.76 ? 565 PHE B N 565 PHE B N 1 ATOM 5712 C CA . PHE B 2 565 ? 31.479 9.028 -3.089 1.00 84.76 ? 565 PHE B CA 565 PHE B CA 1 ATOM 5713 C C . PHE B 2 565 ? 30.261 8.225 -3.531 1.00 84.76 ? 565 PHE B C 565 PHE B C 1 ATOM 5714 O O . PHE B 2 565 ? 30.147 7.854 -4.702 1.00 84.76 ? 565 PHE B O 565 PHE B O 1 ATOM 5715 C CB . PHE B 2 565 ? 32.760 8.237 -3.370 1.00 84.76 ? 565 PHE B CB 565 PHE B CB 1 ATOM 5716 C CG . PHE B 2 565 ? 34.022 8.993 -3.051 1.00 84.76 ? 565 PHE B CG 565 PHE B CG 1 ATOM 5717 C CD1 . PHE B 2 565 ? 34.444 10.041 -3.859 1.00 84.76 ? 565 PHE B CD1 565 PHE B CD1 1 ATOM 5718 C CD2 . PHE B 2 565 ? 34.786 8.654 -1.942 1.00 84.76 ? 565 PHE B CD2 565 PHE B CD2 1 ATOM 5719 C CE1 . PHE B 2 565 ? 35.612 10.742 -3.566 1.00 84.76 ? 565 PHE B CE1 565 PHE B CE1 1 ATOM 5720 C CE2 . PHE B 2 565 ? 35.954 9.350 -1.643 1.00 84.76 ? 565 PHE B CE2 565 PHE B CE2 1 ATOM 5721 C CZ . PHE B 2 565 ? 36.366 10.393 -2.457 1.00 84.76 ? 565 PHE B CZ 565 PHE B CZ 1 ATOM 5722 N N . GLY B 2 566 ? 29.469 7.994 -2.570 1.00 88.86 ? 566 GLY B N 566 GLY B N 1 ATOM 5723 C CA . GLY B 2 566 ? 28.325 7.153 -2.885 1.00 88.86 ? 566 GLY B CA 566 GLY B CA 1 ATOM 5724 C C . GLY B 2 566 ? 27.106 7.944 -3.322 1.00 88.86 ? 566 GLY B C 566 GLY B C 1 ATOM 5725 O O . GLY B 2 566 ? 27.233 9.059 -3.830 1.00 88.86 ? 566 GLY B O 566 GLY B O 1 ATOM 5726 N N . LEU B 2 567 ? 25.945 7.273 -3.275 1.00 91.23 ? 567 LEU B N 567 LEU B N 1 ATOM 5727 C CA . LEU B 2 567 ? 24.664 7.883 -3.612 1.00 91.23 ? 567 LEU B CA 567 LEU B CA 1 ATOM 5728 C C . LEU B 2 567 ? 24.220 8.853 -2.521 1.00 91.23 ? 567 LEU B C 567 LEU B C 1 ATOM 5729 O O . LEU B 2 567 ? 24.299 8.534 -1.332 1.00 91.23 ? 567 LEU B O 567 LEU B O 1 ATOM 5730 C CB . LEU B 2 567 ? 23.595 6.807 -3.820 1.00 91.23 ? 567 LEU B CB 567 LEU B CB 1 ATOM 5731 C CG . LEU B 2 567 ? 23.869 5.785 -4.924 1.00 91.23 ? 567 LEU B CG 567 LEU B CG 1 ATOM 5732 C CD1 . LEU B 2 567 ? 22.882 4.626 -4.831 1.00 91.23 ? 567 LEU B CD1 567 LEU B CD1 1 ATOM 5733 C CD2 . LEU B 2 567 ? 23.795 6.447 -6.296 1.00 91.23 ? 567 LEU B CD2 567 LEU B CD2 1 ATOM 5734 N N . LEU B 2 568 ? 23.900 10.049 -2.916 1.00 92.53 ? 568 LEU B N 568 LEU B N 1 ATOM 5735 C CA . LEU B 2 568 ? 23.440 11.047 -1.957 1.00 92.53 ? 568 LEU B CA 568 LEU B CA 1 ATOM 5736 C C . LEU B 2 568 ? 21.958 10.861 -1.647 1.00 92.53 ? 568 LEU B C 568 LEU B C 1 ATOM 5737 O O . LEU B 2 568 ? 21.101 11.209 -2.461 1.00 92.53 ? 568 LEU B O 568 LEU B O 1 ATOM 5738 C CB . LEU B 2 568 ? 23.687 12.460 -2.492 1.00 92.53 ? 568 LEU B CB 568 LEU B CB 1 ATOM 5739 C CG . LEU B 2 568 ? 25.149 12.861 -2.698 1.00 92.53 ? 568 LEU B CG 568 LEU B CG 1 ATOM 5740 C CD1 . LEU B 2 568 ? 25.234 14.214 -3.397 1.00 92.53 ? 568 LEU B CD1 568 LEU B CD1 1 ATOM 5741 C CD2 . LEU B 2 568 ? 25.887 12.895 -1.363 1.00 92.53 ? 568 LEU B CD2 568 LEU B CD2 1 ATOM 5742 N N . LEU B 2 569 ? 21.646 10.254 -0.499 1.00 92.42 ? 569 LEU B N 569 LEU B N 1 ATOM 5743 C CA . LEU B 2 569 ? 20.283 10.013 -0.041 1.00 92.42 ? 569 LEU B CA 569 LEU B CA 1 ATOM 5744 C C . LEU B 2 569 ? 19.970 10.849 1.196 1.00 92.42 ? 569 LEU B C 569 LEU B C 1 ATOM 5745 O O . LEU B 2 569 ? 20.653 10.735 2.216 1.00 92.42 ? 569 LEU B O 569 LEU B O 1 ATOM 5746 C CB . LEU B 2 569 ? 20.074 8.528 0.267 1.00 92.42 ? 569 LEU B CB 569 LEU B CB 1 ATOM 5747 C CG . LEU B 2 569 ? 20.296 7.558 -0.895 1.00 92.42 ? 569 LEU B CG 569 LEU B CG 1 ATOM 5748 C CD1 . LEU B 2 569 ? 20.398 6.127 -0.377 1.00 92.42 ? 569 LEU B CD1 569 LEU B CD1 1 ATOM 5749 C CD2 . LEU B 2 569 ? 19.174 7.683 -1.919 1.00 92.42 ? 569 LEU B CD2 569 LEU B CD2 1 ATOM 5750 N N . LYS B 2 570 ? 19.021 11.711 1.025 1.00 92.09 ? 570 LYS B N 570 LYS B N 1 ATOM 5751 C CA . LYS B 2 570 ? 18.563 12.521 2.149 1.00 92.09 ? 570 LYS B CA 570 LYS B CA 1 ATOM 5752 C C . LYS B 2 570 ? 17.177 12.082 2.614 1.00 92.09 ? 570 LYS B C 570 LYS B C 1 ATOM 5753 O O . LYS B 2 570 ? 16.335 11.700 1.799 1.00 92.09 ? 570 LYS B O 570 LYS B O 1 ATOM 5754 C CB . LYS B 2 570 ? 18.543 14.003 1.771 1.00 92.09 ? 570 LYS B CB 570 LYS B CB 1 ATOM 5755 C CG . LYS B 2 570 ? 19.925 14.625 1.633 1.00 92.09 ? 570 LYS B CG 570 LYS B CG 1 ATOM 5756 C CD . LYS B 2 570 ? 19.849 16.143 1.542 1.00 92.09 ? 570 LYS B CD 570 LYS B CD 1 ATOM 5757 C CE . LYS B 2 570 ? 21.235 16.773 1.500 1.00 92.09 ? 570 LYS B CE 570 LYS B CE 1 ATOM 5758 N NZ . LYS B 2 570 ? 21.164 18.261 1.404 1.00 92.09 ? 570 LYS B NZ 570 LYS B NZ 1 ATOM 5759 N N . GLU B 2 571 ? 17.001 12.110 3.892 1.00 92.25 ? 571 GLU B N 571 GLU B N 1 ATOM 5760 C CA . GLU B 2 571 ? 15.718 11.710 4.463 1.00 92.25 ? 571 GLU B CA 571 GLU B CA 1 ATOM 5761 C C . GLU B 2 571 ? 15.061 12.868 5.210 1.00 92.25 ? 571 GLU B C 571 GLU B C 1 ATOM 5762 O O . GLU B 2 571 ? 15.739 13.634 5.897 1.00 92.25 ? 571 GLU B O 571 GLU B O 1 ATOM 5763 C CB . GLU B 2 571 ? 15.897 10.514 5.401 1.00 92.25 ? 571 GLU B CB 571 GLU B CB 1 ATOM 5764 C CG . GLU B 2 571 ? 16.504 9.291 4.729 1.00 92.25 ? 571 GLU B CG 571 GLU B CG 1 ATOM 5765 C CD . GLU B 2 571 ? 16.847 8.178 5.707 1.00 92.25 ? 571 GLU B CD 571 GLU B CD 1 ATOM 5766 O OE1 . GLU B 2 571 ? 17.373 7.128 5.271 1.00 92.25 ? 571 GLU B OE1 571 GLU B OE1 1 ATOM 5767 O OE2 . GLU B 2 571 ? 16.587 8.356 6.918 1.00 92.25 ? 571 GLU B OE2 571 GLU B OE2 1 ATOM 5768 N N . THR B 2 572 ? 13.764 13.039 4.995 1.00 91.97 ? 572 THR B N 572 THR B N 1 ATOM 5769 C CA . THR B 2 572 ? 12.995 14.026 5.745 1.00 91.97 ? 572 THR B CA 572 THR B CA 1 ATOM 5770 C C . THR B 2 572 ? 12.792 13.570 7.187 1.00 91.97 ? 572 THR B C 572 THR B C 1 ATOM 5771 O O . THR B 2 572 ? 12.423 12.420 7.434 1.00 91.97 ? 572 THR B O 572 THR B O 1 ATOM 5772 C CB . THR B 2 572 ? 11.627 14.284 5.088 1.00 91.97 ? 572 THR B CB 572 THR B CB 1 ATOM 5773 O OG1 . THR B 2 572 ? 11.825 14.679 3.725 1.00 91.97 ? 572 THR B OG1 572 THR B OG1 1 ATOM 5774 C CG2 . THR B 2 572 ? 10.865 15.386 5.819 1.00 91.97 ? 572 THR B CG2 572 THR B CG2 1 ATOM 5775 N N . GLN B 2 573 ? 13.024 14.494 8.087 1.00 90.15 ? 573 GLN B N 573 GLN B N 1 ATOM 5776 C CA . GLN B 2 573 ? 12.932 14.177 9.508 1.00 90.15 ? 573 GLN B CA 573 GLN B CA 1 ATOM 5777 C C . GLN B 2 573 ? 11.575 14.583 10.077 1.00 90.15 ? 573 GLN B C 573 GLN B C 1 ATOM 5778 O O . GLN B 2 573 ? 10.943 15.518 9.581 1.00 90.15 ? 573 GLN B O 573 GLN B O 1 ATOM 5779 C CB . GLN B 2 573 ? 14.055 14.866 10.286 1.00 90.15 ? 573 GLN B CB 573 GLN B CB 1 ATOM 5780 C CG . GLN B 2 573 ? 15.452 14.460 9.838 1.00 90.15 ? 573 GLN B CG 573 GLN B CG 1 ATOM 5781 C CD . GLN B 2 573 ? 15.775 13.013 10.158 1.00 90.15 ? 573 GLN B CD 573 GLN B CD 1 ATOM 5782 O OE1 . GLN B 2 573 ? 15.255 12.447 11.125 1.00 90.15 ? 573 GLN B OE1 573 GLN B OE1 1 ATOM 5783 N NE2 . GLN B 2 573 ? 16.635 12.404 9.349 1.00 90.15 ? 573 GLN B NE2 573 GLN B NE2 1 ATOM 5784 N N . PRO B 2 574 ? 11.178 13.723 11.086 1.00 87.99 ? 574 PRO B N 574 PRO B N 1 ATOM 5785 C CA . PRO B 2 574 ? 9.933 14.124 11.745 1.00 87.99 ? 574 PRO B CA 574 PRO B CA 1 ATOM 5786 C C . PRO B 2 574 ? 10.040 15.483 12.433 1.00 87.99 ? 574 PRO B C 574 PRO B C 1 ATOM 5787 O O . PRO B 2 574 ? 11.146 15.945 12.725 1.00 87.99 ? 574 PRO B O 574 PRO B O 1 ATOM 5788 C CB . PRO B 2 574 ? 9.700 13.010 12.769 1.00 87.99 ? 574 PRO B CB 574 PRO B CB 1 ATOM 5789 C CG . PRO B 2 574 ? 10.603 11.899 12.336 1.00 87.99 ? 574 PRO B CG 574 PRO B CG 1 ATOM 5790 C CD . PRO B 2 574 ? 11.694 12.477 11.481 1.00 87.99 ? 574 PRO B CD 574 PRO B CD 1 ATOM 5791 N N . MET B 2 575 ? 8.968 16.157 12.637 1.00 85.79 ? 575 MET B N 575 MET B N 1 ATOM 5792 C CA . MET B 2 575 ? 8.919 17.462 13.289 1.00 85.79 ? 575 MET B CA 575 MET B CA 1 ATOM 5793 C C . MET B 2 575 ? 9.339 17.356 14.751 1.00 85.79 ? 575 MET B C 575 MET B C 1 ATOM 5794 O O . MET B 2 575 ? 9.006 16.382 15.428 1.00 85.79 ? 575 MET B O 575 MET B O 1 ATOM 5795 C CB . MET B 2 575 ? 7.516 18.062 13.190 1.00 85.79 ? 575 MET B CB 575 MET B CB 1 ATOM 5796 C CG . MET B 2 575 ? 7.057 18.315 11.763 1.00 85.79 ? 575 MET B CG 575 MET B CG 1 ATOM 5797 S SD . MET B 2 575 ? 5.330 18.931 11.679 1.00 85.79 ? 575 MET B SD 575 MET B SD 1 ATOM 5798 C CE . MET B 2 575 ? 5.571 20.636 12.249 1.00 85.79 ? 575 MET B CE 575 MET B CE 1 ATOM 5799 N N . LYS B 2 576 ? 10.194 18.233 15.186 1.00 79.55 ? 576 LYS B N 576 LYS B N 1 ATOM 5800 C CA . LYS B 2 576 ? 10.634 18.284 16.577 1.00 79.55 ? 576 LYS B CA 576 LYS B CA 1 ATOM 5801 C C . LYS B 2 576 ? 9.531 18.821 17.484 1.00 79.55 ? 576 LYS B C 576 LYS B C 1 ATOM 5802 O O . LYS B 2 576 ? 8.782 19.719 17.093 1.00 79.55 ? 576 LYS B O 576 LYS B O 1 ATOM 5803 C CB . LYS B 2 576 ? 11.890 19.146 16.712 1.00 79.55 ? 576 LYS B CB 576 LYS B CB 1 ATOM 5804 C CG . LYS B 2 576 ? 13.121 18.556 16.040 1.00 79.55 ? 576 LYS B CG 576 LYS B CG 1 ATOM 5805 C CD . LYS B 2 576 ? 14.357 19.412 16.286 1.00 79.55 ? 576 LYS B CD 576 LYS B CD 1 ATOM 5806 C CE . LYS B 2 576 ? 15.580 18.846 15.579 1.00 79.55 ? 576 LYS B CE 576 LYS B CE 1 ATOM 5807 N NZ . LYS B 2 576 ? 16.794 19.683 15.815 1.00 79.55 ? 576 LYS B NZ 576 LYS B NZ 1 ATOM 5808 N N . GLN B 2 577 ? 9.195 18.085 18.491 1.00 64.03 ? 577 GLN B N 577 GLN B N 1 ATOM 5809 C CA . GLN B 2 577 ? 8.248 18.558 19.496 1.00 64.03 ? 577 GLN B CA 577 GLN B CA 1 ATOM 5810 C C . GLN B 2 577 ? 8.790 19.782 20.229 1.00 64.03 ? 577 GLN B C 577 GLN B C 1 ATOM 5811 O O . GLN B 2 577 ? 9.955 19.806 20.631 1.00 64.03 ? 577 GLN B O 577 GLN B O 1 ATOM 5812 C CB . GLN B 2 577 ? 7.927 17.446 20.497 1.00 64.03 ? 577 GLN B CB 577 GLN B CB 1 ATOM 5813 C CG . GLN B 2 577 ? 6.958 16.400 19.963 1.00 64.03 ? 577 GLN B CG 577 GLN B CG 1 ATOM 5814 C CD . GLN B 2 577 ? 6.626 15.332 20.988 1.00 64.03 ? 577 GLN B CD 577 GLN B CD 1 ATOM 5815 O OE1 . GLN B 2 577 ? 7.382 15.106 21.937 1.00 64.03 ? 577 GLN B OE1 577 GLN B OE1 1 ATOM 5816 N NE2 . GLN B 2 577 ? 5.491 14.665 20.803 1.00 64.03 ? 577 GLN B NE2 577 GLN B NE2 1 ATOM 5817 N N . LYS B 2 578 ? 8.396 20.975 19.873 1.00 56.44 ? 578 LYS B N 578 LYS B N 1 ATOM 5818 C CA . LYS B 2 578 ? 8.781 22.121 20.692 1.00 56.44 ? 578 LYS B CA 578 LYS B CA 1 ATOM 5819 C C . LYS B 2 578 ? 8.542 21.842 22.173 1.00 56.44 ? 578 LYS B C 578 LYS B C 1 ATOM 5820 O O . LYS B 2 578 ? 7.463 21.387 22.559 1.00 56.44 ? 578 LYS B O 578 LYS B O 1 ATOM 5821 C CB . LYS B 2 578 ? 8.011 23.371 20.264 1.00 56.44 ? 578 LYS B CB 578 LYS B CB 1 ATOM 5822 C CG . LYS B 2 578 ? 8.635 24.110 19.089 1.00 56.44 ? 578 LYS B CG 578 LYS B CG 1 ATOM 5823 C CD . LYS B 2 578 ? 7.890 25.403 18.783 1.00 56.44 ? 578 LYS B CD 578 LYS B CD 1 ATOM 5824 C CE . LYS B 2 578 ? 8.447 26.089 17.543 1.00 56.44 ? 578 LYS B CE 578 LYS B CE 1 ATOM 5825 N NZ . LYS B 2 578 ? 7.713 27.352 17.233 1.00 56.44 ? 578 LYS B NZ 578 LYS B NZ 1 ATOM 5826 N N . SER B 2 579 ? 9.393 21.153 22.870 1.00 40.12 ? 579 SER B N 579 SER B N 1 ATOM 5827 C CA . SER B 2 579 ? 9.360 21.082 24.327 1.00 40.12 ? 579 SER B CA 579 SER B CA 1 ATOM 5828 C C . SER B 2 579 ? 8.844 22.384 24.932 1.00 40.12 ? 579 SER B C 579 SER B C 1 ATOM 5829 O O . SER B 2 579 ? 9.276 23.470 24.540 1.00 40.12 ? 579 SER B O 579 SER B O 1 ATOM 5830 C CB . SER B 2 579 ? 10.750 20.769 24.881 1.00 40.12 ? 579 SER B CB 579 SER B CB 1 ATOM 5831 O OG . SER B 2 579 ? 11.746 21.494 24.179 1.00 40.12 ? 579 SER B OG 579 SER B OG 1 ATOM 5832 N N . VAL B 2 580 ? 7.642 22.762 24.827 1.00 37.47 ? 580 VAL B N 580 VAL B N 1 ATOM 5833 C CA . VAL B 2 580 ? 7.200 23.832 25.715 1.00 37.47 ? 580 VAL B CA 580 VAL B CA 1 ATOM 5834 C C . VAL B 2 580 ? 8.081 23.865 26.962 1.00 37.47 ? 580 VAL B C 580 VAL B C 1 ATOM 5835 O O . VAL B 2 580 ? 8.182 22.871 27.685 1.00 37.47 ? 580 VAL B O 580 VAL B O 1 ATOM 5836 C CB . VAL B 2 580 ? 5.717 23.663 26.114 1.00 37.47 ? 580 VAL B CB 580 VAL B CB 1 ATOM 5837 C CG1 . VAL B 2 580 ? 5.282 24.779 27.062 1.00 37.47 ? 580 VAL B CG1 580 VAL B CG1 1 ATOM 5838 C CG2 . VAL B 2 580 ? 4.830 23.637 24.870 1.00 37.47 ? 580 VAL B CG2 580 VAL B CG2 1 ATOM 5839 N N . GLU B 2 581 ? 9.420 24.028 26.914 1.00 32.30 ? 581 GLU B N 581 GLU B N 1 ATOM 5840 C CA . GLU B 2 581 ? 10.177 24.544 28.050 1.00 32.30 ? 581 GLU B CA 581 GLU B CA 1 ATOM 5841 C C . GLU B 2 581 ? 9.272 25.298 29.021 1.00 32.30 ? 581 GLU B C 581 GLU B C 1 ATOM 5842 O O . GLU B 2 581 ? 8.566 26.227 28.624 1.00 32.30 ? 581 GLU B O 581 GLU B O 1 ATOM 5843 C CB . GLU B 2 581 ? 11.311 25.455 27.572 1.00 32.30 ? 581 GLU B CB 581 GLU B CB 1 ATOM 5844 C CG . GLU B 2 581 ? 12.555 24.704 27.122 1.00 32.30 ? 581 GLU B CG 581 GLU B CG 1 ATOM 5845 C CD . GLU B 2 581 ? 13.667 25.621 26.636 1.00 32.30 ? 581 GLU B CD 581 GLU B CD 1 ATOM 5846 O OE1 . GLU B 2 581 ? 14.741 25.115 26.239 1.00 32.30 ? 581 GLU B OE1 581 GLU B OE1 1 ATOM 5847 O OE2 . GLU B 2 581 ? 13.462 26.855 26.654 1.00 32.30 ? 581 GLU B OE2 581 GLU B OE2 1 ATOM 5848 N N . THR B 2 582 ? 8.339 24.677 29.711 1.00 32.02 ? 582 THR B N 582 THR B N 1 ATOM 5849 C CA . THR B 2 582 ? 7.923 25.247 30.987 1.00 32.02 ? 582 THR B CA 582 THR B CA 1 ATOM 5850 C C . THR B 2 582 ? 9.028 26.119 31.576 1.00 32.02 ? 582 THR B C 582 THR B C 1 ATOM 5851 O O . THR B 2 582 ? 10.145 25.647 31.800 1.00 32.02 ? 582 THR B O 582 THR B O 1 ATOM 5852 C CB . THR B 2 582 ? 7.543 24.146 31.994 1.00 32.02 ? 582 THR B CB 582 THR B CB 1 ATOM 5853 O OG1 . THR B 2 582 ? 8.103 22.899 31.564 1.00 32.02 ? 582 THR B OG1 582 THR B OG1 1 ATOM 5854 C CG2 . THR B 2 582 ? 6.029 23.998 32.103 1.00 32.02 ? 582 THR B CG2 582 THR B CG2 1 ATOM 5855 N N . SER B 2 583 ? 9.486 27.203 30.952 1.00 30.16 ? 583 SER B N 583 SER B N 1 ATOM 5856 C CA . SER B 2 583 ? 9.904 28.352 31.749 1.00 30.16 ? 583 SER B CA 583 SER B CA 1 ATOM 5857 C C . SER B 2 583 ? 9.143 28.415 33.069 1.00 30.16 ? 583 SER B C 583 SER B C 1 ATOM 5858 O O . SER B 2 583 ? 7.946 28.713 33.088 1.00 30.16 ? 583 SER B O 583 SER B O 1 ATOM 5859 C CB . SER B 2 583 ? 9.695 29.650 30.968 1.00 30.16 ? 583 SER B CB 583 SER B CB 1 ATOM 5860 O OG . SER B 2 583 ? 8.366 29.738 30.483 1.00 30.16 ? 583 SER B OG 583 SER B OG 1 ATOM 5861 N N . ASN B 2 584 ? 9.181 27.405 33.895 1.00 33.07 ? 584 ASN B N 584 ASN B N 1 ATOM 5862 C CA . ASN B 2 584 ? 9.015 27.772 35.297 1.00 33.07 ? 584 ASN B CA 584 ASN B CA 1 ATOM 5863 C C . ASN B 2 584 ? 10.355 28.082 35.959 1.00 33.07 ? 584 ASN B C 584 ASN B C 1 ATOM 5864 O O . ASN B 2 584 ? 11.134 27.172 36.247 1.00 33.07 ? 584 ASN B O 584 ASN B O 1 ATOM 5865 C CB . ASN B 2 584 ? 8.290 26.661 36.060 1.00 33.07 ? 584 ASN B CB 584 ASN B CB 1 ATOM 5866 C CG . ASN B 2 584 ? 6.782 26.757 35.938 1.00 33.07 ? 584 ASN B CG 584 ASN B CG 1 ATOM 5867 O OD1 . ASN B 2 584 ? 6.251 27.729 35.394 1.00 33.07 ? 584 ASN B OD1 584 ASN B OD1 1 ATOM 5868 N ND2 . ASN B 2 584 ? 6.081 25.749 36.443 1.00 33.07 ? 584 ASN B ND2 584 ASN B ND2 1 ATOM 5869 N N . GLY B 2 585 ? 11.257 28.965 35.481 1.00 28.72 ? 585 GLY B N 585 GLY B N 1 ATOM 5870 C CA . GLY B 2 585 ? 12.038 29.972 36.181 1.00 28.72 ? 585 GLY B CA 585 GLY B CA 1 ATOM 5871 C C . GLY B 2 585 ? 11.190 30.903 37.027 1.00 28.72 ? 585 GLY B C 585 GLY B C 1 ATOM 5872 O O . GLY B 2 585 ? 10.182 31.434 36.556 1.00 28.72 ? 585 GLY B O 585 GLY B O 1 ATOM 5873 N N . GLY B 2 586 ? 10.893 30.558 38.285 1.00 25.56 ? 586 GLY B N 586 GLY B N 1 ATOM 5874 C CA . GLY B 2 586 ? 11.171 31.478 39.377 1.00 25.56 ? 586 GLY B CA 586 GLY B CA 1 ATOM 5875 C C . GLY B 2 586 ? 9.916 32.067 39.994 1.00 25.56 ? 586 GLY B C 586 GLY B C 1 ATOM 5876 O O . GLY B 2 586 ? 8.998 32.472 39.279 1.00 25.56 ? 586 GLY B O 586 GLY B O 1 ATOM 5877 N N . VAL B 2 587 ? 9.530 31.634 41.163 1.00 26.58 ? 587 VAL B N 587 VAL B N 1 ATOM 5878 C CA . VAL B 2 587 ? 9.442 32.325 42.446 1.00 26.58 ? 587 VAL B CA 587 VAL B CA 1 ATOM 5879 C C . VAL B 2 587 ? 7.976 32.521 42.828 1.00 26.58 ? 587 VAL B C 587 VAL B C 1 ATOM 5880 O O . VAL B 2 587 ? 7.180 33.014 42.026 1.00 26.58 ? 587 VAL B O 587 VAL B O 1 ATOM 5881 C CB . VAL B 2 587 ? 10.169 33.688 42.407 1.00 26.58 ? 587 VAL B CB 587 VAL B CB 1 ATOM 5882 C CG1 . VAL B 2 587 ? 10.110 34.370 43.773 1.00 26.58 ? 587 VAL B CG1 587 VAL B CG1 1 ATOM 5883 C CG2 . VAL B 2 587 ? 11.618 33.506 41.960 1.00 26.58 ? 587 VAL B CG2 587 VAL B CG2 1 ATOM 5884 N N . GLU B 2 588 ? 7.573 31.823 43.898 1.00 24.93 ? 588 GLU B N 588 GLU B N 1 ATOM 5885 C CA . GLU B 2 588 ? 7.200 32.469 45.154 1.00 24.93 ? 588 GLU B CA 588 GLU B CA 1 ATOM 5886 C C . GLU B 2 588 ? 5.690 32.432 45.366 1.00 24.93 ? 588 GLU B C 588 GLU B C 1 ATOM 5887 O O . GLU B 2 588 ? 4.924 32.833 44.487 1.00 24.93 ? 588 GLU B O 588 GLU B O 1 ATOM 5888 C CB . GLU B 2 588 ? 7.701 33.915 45.184 1.00 24.93 ? 588 GLU B CB 588 GLU B CB 1 ATOM 5889 C CG . GLU B 2 588 ? 8.953 34.115 46.024 1.00 24.93 ? 588 GLU B CG 588 GLU B CG 1 ATOM 5890 C CD . GLU B 2 588 ? 9.400 35.567 46.100 1.00 24.93 ? 588 GLU B CD 588 GLU B CD 1 ATOM 5891 O OE1 . GLU B 2 588 ? 10.404 35.858 46.789 1.00 24.93 ? 588 GLU B OE1 588 GLU B OE1 1 ATOM 5892 O OE2 . GLU B 2 588 ? 8.740 36.420 45.466 1.00 24.93 ? 588 GLU B OE2 588 GLU B OE2 1 ATOM 5893 N N . GLU B 2 589 ? 5.279 31.610 46.420 1.00 27.65 ? 589 GLU B N 589 GLU B N 1 ATOM 5894 C CA . GLU B 2 589 ? 4.782 32.117 47.695 1.00 27.65 ? 589 GLU B CA 589 GLU B CA 1 ATOM 5895 C C . GLU B 2 589 ? 3.368 32.675 47.554 1.00 27.65 ? 589 GLU B C 589 GLU B C 1 ATOM 5896 O O . GLU B 2 589 ? 3.089 33.447 46.635 1.00 27.65 ? 589 GLU B O 589 GLU B O 1 ATOM 5897 C CB . GLU B 2 589 ? 5.719 33.194 48.248 1.00 27.65 ? 589 GLU B CB 589 GLU B CB 1 ATOM 5898 C CG . GLU B 2 589 ? 6.547 32.737 49.440 1.00 27.65 ? 589 GLU B CG 589 GLU B CG 1 ATOM 5899 C CD . GLU B 2 589 ? 7.455 33.823 49.992 1.00 27.65 ? 589 GLU B CD 589 GLU B CD 1 ATOM 5900 O OE1 . GLU B 2 589 ? 8.193 33.560 50.969 1.00 27.65 ? 589 GLU B OE1 589 GLU B OE1 1 ATOM 5901 O OE2 . GLU B 2 589 ? 7.429 34.948 49.444 1.00 27.65 ? 589 GLU B OE2 589 GLU B OE2 1 ATOM 5902 N N . THR B 2 590 ? 2.414 32.027 48.183 1.00 30.51 ? 590 THR B N 590 THR B N 1 ATOM 5903 C CA . THR B 2 590 ? 1.509 32.388 49.268 1.00 30.51 ? 590 THR B CA 590 THR B CA 1 ATOM 5904 C C . THR B 2 590 ? 0.142 32.788 48.722 1.00 30.51 ? 590 THR B C 590 THR B C 1 ATOM 5905 O O . THR B 2 590 ? 0.052 33.542 47.750 1.00 30.51 ? 590 THR B O 590 THR B O 1 ATOM 5906 C CB . THR B 2 590 ? 2.083 33.538 50.115 1.00 30.51 ? 590 THR B CB 590 THR B CB 1 ATOM 5907 O OG1 . THR B 2 590 ? 2.630 34.538 49.246 1.00 30.51 ? 590 THR B OG1 590 THR B OG1 1 ATOM 5908 C CG2 . THR B 2 590 ? 3.181 33.039 51.050 1.00 30.51 ? 590 THR B CG2 590 THR B CG2 1 ATOM 5909 N N . MET B 2 591 ? -0.868 31.987 48.826 1.00 27.24 ? 591 MET B N 591 MET B N 1 ATOM 5910 C CA . MET B 2 591 ? -2.155 32.571 49.193 1.00 27.24 ? 591 MET B CA 591 MET B CA 1 ATOM 5911 C C . MET B 2 591 ? -3.193 31.484 49.451 1.00 27.24 ? 591 MET B C 591 MET B C 1 ATOM 5912 O O . MET B 2 591 ? -3.337 30.556 48.653 1.00 27.24 ? 591 MET B O 591 MET B O 1 ATOM 5913 C CB . MET B 2 591 ? -2.650 33.516 48.097 1.00 27.24 ? 591 MET B CB 591 MET B CB 1 ATOM 5914 C CG . MET B 2 591 ? -3.148 34.854 48.620 1.00 27.24 ? 591 MET B CG 591 MET B CG 1 ATOM 5915 S SD . MET B 2 591 ? -3.749 35.953 47.279 1.00 27.24 ? 591 MET B SD 591 MET B SD 1 ATOM 5916 C CE . MET B 2 591 ? -4.540 37.256 48.263 1.00 27.24 ? 591 MET B CE 591 MET B CE 1 ATOM 5917 N N . LYS B 2 592 ? -3.482 31.171 50.763 1.00 26.06 ? 592 LYS B N 592 LYS B N 1 ATOM 5918 C CA . LYS B 2 592 ? -4.744 31.472 51.433 1.00 26.06 ? 592 LYS B CA 592 LYS B CA 1 ATOM 5919 C C . LYS B 2 592 ? -5.748 30.338 51.249 1.00 26.06 ? 592 LYS B C 592 LYS B C 1 ATOM 5920 O O . LYS B 2 592 ? -5.970 29.873 50.129 1.00 26.06 ? 592 LYS B O 592 LYS B O 1 ATOM 5921 C CB . LYS B 2 592 ? -5.332 32.783 50.907 1.00 26.06 ? 592 LYS B CB 592 LYS B CB 1 ATOM 5922 C CG . LYS B 2 592 ? -4.862 34.018 51.662 1.00 26.06 ? 592 LYS B CG 592 LYS B CG 1 ATOM 5923 C CD . LYS B 2 592 ? -5.618 35.264 51.219 1.00 26.06 ? 592 LYS B CD 592 LYS B CD 1 ATOM 5924 C CE . LYS B 2 592 ? -5.133 36.505 51.956 1.00 26.06 ? 592 LYS B CE 592 LYS B CE 1 ATOM 5925 N NZ . LYS B 2 592 ? -5.859 37.733 51.511 1.00 26.06 ? 592 LYS B NZ 592 LYS B NZ 1 ATOM 5926 N N . MET B 2 593 ? -5.942 29.543 52.285 1.00 35.02 ? 593 MET B N 593 MET B N 1 ATOM 5927 C CA . MET B 2 593 ? -7.032 28.980 53.076 1.00 35.02 ? 593 MET B CA 593 MET B CA 1 ATOM 5928 C C . MET B 2 593 ? -6.937 27.459 53.128 1.00 35.02 ? 593 MET B C 593 MET B C 1 ATOM 5929 O O . MET B 2 593 ? -6.739 26.809 52.099 1.00 35.02 ? 593 MET B O 593 MET B O 1 ATOM 5930 C CB . MET B 2 593 ? -8.386 29.399 52.501 1.00 35.02 ? 593 MET B CB 593 MET B CB 1 ATOM 5931 C CG . MET B 2 593 ? -8.867 30.756 52.991 1.00 35.02 ? 593 MET B CG 593 MET B CG 1 ATOM 5932 S SD . MET B 2 593 ? -10.696 30.897 52.987 1.00 35.02 ? 593 MET B SD 593 MET B SD 1 ATOM 5933 C CE . MET B 2 593 ? -10.879 32.671 52.656 1.00 35.02 ? 593 MET B CE 593 MET B CE 1 _database_2.database_id ModelArchive _database_2.database_code ma-bak-cepc-0634 _database_2.pdbx_DOI 10.5452/ma-bak-cepc-0634 _pdbx_database_status.entry_id ma-bak-cepc-0634 _pdbx_database_status.date_coordinates 2021-11-12:08:53 _pdbx_database_status.status_code REL loop_ _pdbx_contact_author.id _pdbx_contact_author.name_salutation _pdbx_contact_author.name_first _pdbx_contact_author.name_last _pdbx_contact_author.name_mi _pdbx_contact_author.email _pdbx_contact_author.address_1 _pdbx_contact_author.address_2 _pdbx_contact_author.address_3 29 . Qian Cong . qian.cong@utsouthwestern.edu 'University of Texas Southwestern Medical Center' . . 30 . David Baker . dabaker@uw.edu 'University of Washington' . . loop_ _entity_poly.entity_id _entity_poly.type _entity_poly.nstd_linkage _entity_poly.nstd_monomer _entity_poly.pdbx_seq_one_letter_code _entity_poly.pdbx_seq_one_letter_code_can _entity_poly.pdbx_strand_id _entity_poly.pdbx_target_identifier 1 "polypeptide(L)" no no ;MPSKNSINRPKLTSNLHHKVHSLNKKRAQRERAGLLKPARSSVNSKSGEIKSVALDLYFQNKKNESQNSTAVTLQNASSS PASITTRTLSKKRAKKIERNLKYATQRKLLVDASAKLEDEMDIDLDGGKKVKENEKKSSLTLVKEALWSVIDDTASQGLI IENGQGTTLGGPFFP ; ;MPSKNSINRPKLTSNLHHKVHSLNKKRAQRERAGLLKPARSSVNSKSGEIKSVALDLYFQNKKNESQNSTAVTLQNASSS PASITTRTLSKKRAKKIERNLKYATQRKLLVDASAKLEDEMDIDLDGGKKVKENEKKSSLTLVKEALWSVIDDTASQGLI IENGQGTTLGGPFFP ; A ? 2 "polypeptide(L)" no no ;MALAISHEDTQILLKDKNILQESVLNKYRTAGQIAQTALKYVTSLINDSYHSKTTQRQLTVPELCLLTDSFILTRLEQYY KNKVNERGIAIPTTIDIDQISGGWCPEIDDTQNLLNWNKGKDSTFASSVTGTLRPGDLVKITLGVHIDGYTSEVSHTMVI YPVDETKPIPQPTGPLLGGKADAVAAAHIAMETVVALLACALTPEKLPASLGGTSSGITGQLIRTIVDTIARSYNCGVVP GSRVRRIRRFLAGQNEGIVAEREYKGVVWTESHQEADLLSNTDAKDLTVVDRGQSTPFTNVSAIPSDDFVVQSGEVYLID LKMASLEHCTKKGLVTLETVDSYTGKSHKAGELIARPGAYVRDFAQTHILKLKTSRQLLTKIDKQGVYPFKLSHLSSNFP FVHENEEELQSLKKDLKSFRLGMSEISNNYLCVESPIQIARWVPWDHILKATNPNGNLSYDATSTLTLPGHELPLPKLGV SAIKLKSLMNSTKESISLPVARECNTIVLCDSSVSTTDRPELLRLTGGSKTCQPSWIHSQHELNPQDSIVQGIFQLATLA KDKRFGLLLKETQPMKQKSVETSNGGVEETMKM ; ;MALAISHEDTQILLKDKNILQESVLNKYRTAGQIAQTALKYVTSLINDSYHSKTTQRQLTVPELCLLTDSFILTRLEQYY KNKVNERGIAIPTTIDIDQISGGWCPEIDDTQNLLNWNKGKDSTFASSVTGTLRPGDLVKITLGVHIDGYTSEVSHTMVI YPVDETKPIPQPTGPLLGGKADAVAAAHIAMETVVALLACALTPEKLPASLGGTSSGITGQLIRTIVDTIARSYNCGVVP GSRVRRIRRFLAGQNEGIVAEREYKGVVWTESHQEADLLSNTDAKDLTVVDRGQSTPFTNVSAIPSDDFVVQSGEVYLID LKMASLEHCTKKGLVTLETVDSYTGKSHKAGELIARPGAYVRDFAQTHILKLKTSRQLLTKIDKQGVYPFKLSHLSSNFP FVHENEEELQSLKKDLKSFRLGMSEISNNYLCVESPIQIARWVPWDHILKATNPNGNLSYDATSTLTLPGHELPLPKLGV SAIKLKSLMNSTKESISLPVARECNTIVLCDSSVSTTDRPELLRLTGGSKTCQPSWIHSQHELNPQDSIVQGIFQLATLA KDKRFGLLLKETQPMKQKSVETSNGGVEETMKM ; B ? loop_ _ma_model_list.data_id _ma_model_list.model_group_id _ma_model_list.model_group_name _ma_model_list.model_id _ma_model_list.model_name _ma_model_list.model_type _ma_model_list.ordinal_id 1 1 "AlphaFold model" 1 "Model 3" "Ab initio model" 1 loop_ _audit_conform.dict_name _audit_conform.dict_version _audit_conform.dict_location mmcif_ma.dic 1.4.5 https://raw.githubusercontent.com/ihmwg/ModelCIF/ba728c4/archive/mmcif_ma-v1.4.5.dic loop_ _pdbx_audit_revision_history.ordinal _pdbx_audit_revision_history.data_content_type _pdbx_audit_revision_history.major_revision _pdbx_audit_revision_history.minor_revision _pdbx_audit_revision_history.revision_date 1 'Structure model' 1 0 2021-11-11 2 'Structure model' 1 1 2022-11-30 3 'Structure model' 1 2 2023-07-17 4 'Structure model' 1 3 2023-07-19 5 'Structure model' 1 4 2023-07-26 6 'Structure model' 1 5 2024-03-04 loop_ _pdbx_audit_revision_details.ordinal _pdbx_audit_revision_details.revision_ordinal _pdbx_audit_revision_details.data_content_type _pdbx_audit_revision_details.provider _pdbx_audit_revision_details.type _pdbx_audit_revision_details.description 1 1 'Structure model' repository 'Initial release' ? 2 2 'Structure model' repository Remediation 'Format fixes, new metadata' 3 5 'Structure model' repository Remediation 'Format compliance remediation' loop_ _pdbx_audit_revision_group.ordinal _pdbx_audit_revision_group.revision_ordinal _pdbx_audit_revision_group.data_content_type _pdbx_audit_revision_group.group 1 3 'Structure model' Other 2 4 'Structure model' Other 3 5 'Structure model' Other 4 5 'Structure model' 'Version format compliance' 5 6 'Structure model' 'Structure summary' loop_ _pdbx_audit_revision_category.ordinal _pdbx_audit_revision_category.revision_ordinal _pdbx_audit_revision_category.data_content_type _pdbx_audit_revision_category.category 1 3 'Structure model' ma_associated_archive_file_details 2 4 'Structure model' exptl 3 4 'Structure model' struct 4 5 'Structure model' ma_data 5 5 'Structure model' ma_target_entity 6 5 'Structure model' ma_associated_archive_file_details 7 5 'Structure model' audit_conform 8 6 'Structure model' struct loop_ _pdbx_audit_revision_item.ordinal _pdbx_audit_revision_item.revision_ordinal _pdbx_audit_revision_item.data_content_type _pdbx_audit_revision_item.item 1 3 'Structure model' '_ma_associated_archive_file_details.file_path' 2 4 'Structure model' '_exptl.entry_id' 3 4 'Structure model' '_exptl.method' 4 4 'Structure model' '_struct.pdbx_structure_determination_methodology' 5 5 'Structure model' '_ma_data.content_type' 6 5 'Structure model' '_ma_data.id' 7 5 'Structure model' '_ma_data.name' 8 5 'Structure model' '_ma_target_entity.data_id' 9 5 'Structure model' '_ma_associated_archive_file_details.data_id' 10 5 'Structure model' '_audit_conform.dict_location' 11 5 'Structure model' '_audit_conform.dict_name' 12 5 'Structure model' '_audit_conform.dict_version' 13 6 'Structure model' '_struct.pdbx_model_details'